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Overview

ID MAG01127
Name EH3_bin.91
Sample SMP0030
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family JACTUA01
Genus JAJRCM01
Species
Assembly information
Completeness (%) 75.31
Contamination (%) 0.42
GC content (%) 53.0
N50 (bp) 18,501
Genome size (bp) 1,050,714

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1171

Gene name Description KEGG GOs EC E-value Score Sequence
EH3_k127_1127541_0 Protein of unknown function (DUF460) K09150 - - 5.616e-231 732.0
EH3_k127_1127541_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 2.703e-199 623.0
EH3_k127_1127541_10 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 325.0
EH3_k127_1127541_11 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 316.0
EH3_k127_1127541_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 311.0
EH3_k127_1127541_13 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 288.0
EH3_k127_1127541_14 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 289.0
EH3_k127_1127541_15 FHA domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000017 273.0
EH3_k127_1127541_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 257.0
EH3_k127_1127541_17 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000000000000000000000000000000000000000000000003777 216.0
EH3_k127_1127541_18 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000001124 191.0
EH3_k127_1127541_19 PFAM ribosomal protein S8E K02995 - - 0.00000000000000000000000000000000000000000000000434 175.0
EH3_k127_1127541_2 Domain of unknown function DUF87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 504.0
EH3_k127_1127541_20 - - - - 0.000000000000000000000000000000000000000002408 162.0
EH3_k127_1127541_21 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000000000000000000000005573 146.0
EH3_k127_1127541_22 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.00000000000000000000000000000002158 129.0
EH3_k127_1127541_23 RNA-binding protein involved in rRNA processing K07569 - - 0.0000000000000000001358 92.0
EH3_k127_1127541_24 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.00000000000001832 76.0
EH3_k127_1127541_3 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 450.0
EH3_k127_1127541_4 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 397.0
EH3_k127_1127541_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 389.0
EH3_k127_1127541_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 375.0
EH3_k127_1127541_7 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 357.0
EH3_k127_1127541_8 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 346.0
EH3_k127_1127541_9 Rio2, N-terminal K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 338.0
EH3_k127_1132493_0 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 516.0
EH3_k127_1132493_1 sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 339.0
EH3_k127_1132493_2 aminotransferase class I and II K00812 - 2.6.1.1 0.0000009454 51.0
EH3_k127_1143204_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1283.0
EH3_k127_1143204_1 Transport of potassium into the cell K03549 - - 5.054e-261 816.0
EH3_k127_1143204_10 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 458.0
EH3_k127_1143204_11 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 445.0
EH3_k127_1143204_12 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 410.0
EH3_k127_1143204_13 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 391.0
EH3_k127_1143204_14 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 394.0
EH3_k127_1143204_15 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 356.0
EH3_k127_1143204_16 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 338.0
EH3_k127_1143204_17 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 316.0
EH3_k127_1143204_18 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 301.0
EH3_k127_1143204_19 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 295.0
EH3_k127_1143204_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.377e-235 736.0
EH3_k127_1143204_20 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 293.0
EH3_k127_1143204_21 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 277.0
EH3_k127_1143204_22 PFAM thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001619 259.0
EH3_k127_1143204_23 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000006142 255.0
EH3_k127_1143204_24 deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000009766 244.0
EH3_k127_1143204_25 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000000000000003711 227.0
EH3_k127_1143204_26 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000006294 224.0
EH3_k127_1143204_27 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000855 221.0
EH3_k127_1143204_28 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000007492 216.0
EH3_k127_1143204_29 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000002783 215.0
EH3_k127_1143204_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.718e-230 720.0
EH3_k127_1143204_30 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000001461 207.0
EH3_k127_1143204_31 PFAM regulatory protein, ArsR K07721 - - 0.0000000000000000000000000000000000000000000000000000005097 199.0
EH3_k127_1143204_32 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000006294 205.0
EH3_k127_1143204_33 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.000000000000000000000000000000000000000000000000001287 190.0
EH3_k127_1143204_34 binds to the 23S rRNA K02921 - - 0.000000000000000000000000000000000000000000141 160.0
EH3_k127_1143204_35 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000000000000000916 150.0
EH3_k127_1143204_36 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000009489 150.0
EH3_k127_1143204_37 PFAM response regulator receiver - - - 0.000000000000000000000000000000000008433 145.0
EH3_k127_1143204_38 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000000009123 138.0
EH3_k127_1143204_39 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.0000000000000000000000000000000001215 142.0
EH3_k127_1143204_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.331e-197 622.0
EH3_k127_1143204_40 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0000000000000000000000000000000001427 138.0
EH3_k127_1143204_41 Small multi-drug export protein - - - 0.0000000000000000000000000000000001449 141.0
EH3_k127_1143204_42 HEAT repeats - - - 0.0000000000000000000000001043 113.0
EH3_k127_1143204_43 ATP synthase subunit C K02124 - - 0.00000000000000000000001842 101.0
EH3_k127_1143204_44 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000000000000000002383 90.0
EH3_k127_1143204_45 PFAM Metallophosphoesterase - - - 0.0000000000000000001416 91.0
EH3_k127_1143204_46 TfoX N-terminal domain - - - 0.0000000000000001041 86.0
EH3_k127_1143204_47 metallopeptidase activity - - - 0.0000000000000001077 86.0
EH3_k127_1143204_48 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000002951 79.0
EH3_k127_1143204_49 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000003762 77.0
EH3_k127_1143204_5 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 610.0
EH3_k127_1143204_50 PBS lyase HEAT-like repeat - - - 0.0000000007154 66.0
EH3_k127_1143204_51 - - - - 0.000000002484 59.0
EH3_k127_1143204_52 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.000005226 55.0
EH3_k127_1143204_53 COG0464 ATPases of the AAA class K13525 - - 0.00001842 55.0
EH3_k127_1143204_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 567.0
EH3_k127_1143204_7 TGS domain protein K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 560.0
EH3_k127_1143204_8 TIGRFAM small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 529.0
EH3_k127_1143204_9 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 475.0
EH3_k127_1178726_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.76e-231 721.0
EH3_k127_1178726_1 TIGRFAM TraB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 477.0
EH3_k127_1178726_10 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000003346 166.0
EH3_k127_1178726_11 - - - - 0.0000000000000000000000000001561 121.0
EH3_k127_1178726_2 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 435.0
EH3_k127_1178726_3 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 419.0
EH3_k127_1178726_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000005458 264.0
EH3_k127_1178726_5 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003867 224.0
EH3_k127_1178726_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000003736 224.0
EH3_k127_1178726_7 PFAM Phosphatidylglycerophosphatase A - - - 0.0000000000000000000000000000000000000000000000000000000002266 211.0
EH3_k127_1178726_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000003467 201.0
EH3_k127_1178726_9 Belongs to the UPF0305 family - - - 0.0000000000000000000000000000000000000000000000000002852 190.0
EH3_k127_1221263_0 Protein-export membrane protein SecD K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 326.0
EH3_k127_1221263_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 286.0
EH3_k127_1221263_2 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000006871 135.0
EH3_k127_1221263_3 PFAM HhH-GPD family protein K07457 - - 0.0000000000005984 72.0
EH3_k127_1234194_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.637e-220 697.0
EH3_k127_1234194_1 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 1.999e-196 617.0
EH3_k127_1234194_10 CBS domain containing protein - - - 0.00000000000000000000000001139 113.0
EH3_k127_1234194_11 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000001696 107.0
EH3_k127_1234194_12 - - - - 0.000000000000000005051 90.0
EH3_k127_1234194_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00001304 49.0
EH3_k127_1234194_2 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 447.0
EH3_k127_1234194_3 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 434.0
EH3_k127_1234194_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 311.0
EH3_k127_1234194_5 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000000000000000000000281 190.0
EH3_k127_1234194_6 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000000000000000000000000004249 162.0
EH3_k127_1234194_7 - - - - 0.0000000000000000000000000000000005963 141.0
EH3_k127_1234194_8 - - - - 0.000000000000000000000000000002609 124.0
EH3_k127_1234194_9 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000007276 125.0
EH3_k127_1252612_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 548.0
EH3_k127_1252612_1 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 475.0
EH3_k127_1252612_2 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 435.0
EH3_k127_1252612_3 coenzyme F420-reducing hydrogenase, delta subunit K00442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002321 242.0
EH3_k127_1252612_4 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.0000000000000001817 79.0
EH3_k127_1259831_0 KH, type 1, domain K07041 - - 0.0 1134.0
EH3_k127_1259831_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000003061 196.0
EH3_k127_1259831_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000009304 100.0
EH3_k127_1260068_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 500.0
EH3_k127_1260068_1 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 340.0
EH3_k127_1260068_2 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000001476 231.0
EH3_k127_1291489_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 1.573e-228 717.0
EH3_k127_1291489_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 411.0
EH3_k127_1291489_10 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000000002154 88.0
EH3_k127_1291489_11 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000001196 85.0
EH3_k127_1291489_2 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 367.0
EH3_k127_1291489_3 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 306.0
EH3_k127_1291489_4 Domain of unknown function (DUF1917) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 289.0
EH3_k127_1291489_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000002117 243.0
EH3_k127_1291489_6 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000000000000000000000000000385 194.0
EH3_k127_1291489_7 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000000000000005597 117.0
EH3_k127_1291489_8 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000000000001203 115.0
EH3_k127_1291489_9 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000000000000000000001689 115.0
EH3_k127_1309456_0 PFAM ribonuclease II K01147 - 3.1.13.1 1.509e-203 644.0
EH3_k127_1309456_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 421.0
EH3_k127_1309456_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 343.0
EH3_k127_1309456_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 323.0
EH3_k127_1309456_4 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 303.0
EH3_k127_1309456_5 PFAM Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004568 248.0
EH3_k127_1309456_6 Flavodoxin - - - 0.000000000000000000000000000000000000000001208 162.0
EH3_k127_1309456_7 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000006398 156.0
EH3_k127_1309456_8 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000000000001559 137.0
EH3_k127_1309456_9 ABC-2 type transporter K01992 - - 0.000000002415 60.0
EH3_k127_131675_0 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 426.0
EH3_k127_131675_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000001826 235.0
EH3_k127_131675_2 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000000000000000005074 111.0
EH3_k127_1343495_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 465.0
EH3_k127_1343495_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 372.0
EH3_k127_1343495_2 Functions by promoting the formation of the first peptide bond K03263 - - 0.0000000000000000000000000000000000000000000000000000000005796 203.0
EH3_k127_1343495_3 Ribonuclease H K03469 - 3.1.26.4 0.000000000000000000000000000001275 125.0
EH3_k127_1343495_4 - - - - 0.00000000000000000000000000004841 118.0
EH3_k127_1343495_5 COG1881 Phospholipid-binding protein K06910 - - 0.00000000000000000003097 98.0
EH3_k127_1343495_6 COG1881 Phospholipid-binding protein K06910 - - 0.0000001623 53.0
EH3_k127_1343495_7 COG1881 Phospholipid-binding protein K06910 - - 0.000000578 54.0
EH3_k127_1413615_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0 1182.0
EH3_k127_1413615_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1107.0
EH3_k127_1413615_10 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 319.0
EH3_k127_1413615_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000009067 239.0
EH3_k127_1413615_12 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000002531 212.0
EH3_k127_1413615_13 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000003812 201.0
EH3_k127_1413615_14 N-4 methylation of cytosine K00571,K00590 - 2.1.1.113,2.1.1.72 0.00000000000000000000000000000000000000001166 154.0
EH3_k127_1413615_15 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000000000000000000002047 154.0
EH3_k127_1413615_16 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001725 114.0
EH3_k127_1413615_2 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 1.852e-275 863.0
EH3_k127_1413615_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 8.44e-218 684.0
EH3_k127_1413615_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.695e-199 629.0
EH3_k127_1413615_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.235e-196 625.0
EH3_k127_1413615_6 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 453.0
EH3_k127_1413615_7 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
EH3_k127_1413615_8 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 323.0
EH3_k127_1413615_9 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 322.0
EH3_k127_1553968_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 509.0
EH3_k127_1553968_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 360.0
EH3_k127_1553968_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000000000008005 212.0
EH3_k127_1553968_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000000000000000001111 211.0
EH3_k127_1553968_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000003351 201.0
EH3_k127_1553968_13 binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000000000000000000000006321 187.0
EH3_k127_1553968_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000000000004762 176.0
EH3_k127_1553968_15 PFAM sigma-70 region 4 domain protein K09714 - - 0.000000000000000000000000000000000000000000000003319 176.0
EH3_k127_1553968_16 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.0000000000000000000000000000000000000000000704 164.0
EH3_k127_1553968_17 PFAM Ribosomal protein K02912 - - 0.0000000000000000000000000000000000321 140.0
EH3_k127_1553968_18 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.000000000000000000000002036 102.0
EH3_k127_1553968_19 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000000023 106.0
EH3_k127_1553968_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 351.0
EH3_k127_1553968_20 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.00000000000000000000004649 103.0
EH3_k127_1553968_21 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000005169 93.0
EH3_k127_1553968_22 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.0000000006496 64.0
EH3_k127_1553968_3 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 347.0
EH3_k127_1553968_4 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 297.0
EH3_k127_1553968_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000001017 236.0
EH3_k127_1553968_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000000000000000001055 231.0
EH3_k127_1553968_7 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.000000000000000000000000000000000000000000000000000000000000000001187 228.0
EH3_k127_1553968_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000004522 225.0
EH3_k127_1553968_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000003241 218.0
EH3_k127_162220_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 1.973e-200 631.0
EH3_k127_162220_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 2.646e-200 634.0
EH3_k127_162220_2 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.458e-199 630.0
EH3_k127_162220_3 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 488.0
EH3_k127_162220_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 394.0
EH3_k127_162220_5 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 388.0
EH3_k127_162220_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 346.0
EH3_k127_162220_7 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.0000000000000000000000000000000004314 132.0
EH3_k127_20109_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 8.028e-319 981.0
EH3_k127_20109_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 1.243e-293 908.0
EH3_k127_20109_10 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00579 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 334.0
EH3_k127_20109_11 PFAM Methyl-coenzyme M reductase, protein D K03422 - - 0.0000000000000000000000000000000000000000000000000001955 189.0
EH3_k127_20109_12 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00578 - 2.1.1.86 0.0000000000000000000000000000000007154 132.0
EH3_k127_20109_13 Molybdopterin oxidoreductase K00201 - 1.2.7.12 0.0000000000000000002319 87.0
EH3_k127_20109_14 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.0000000000001187 70.0
EH3_k127_20109_15 TIGRFAM tetrahydromethanopterin S-methyltransferase, F subunit K00582 - 2.1.1.86 0.0000000000002213 73.0
EH3_k127_20109_16 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000006833 62.0
EH3_k127_20109_2 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 1.001e-214 673.0
EH3_k127_20109_3 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 560.0
EH3_k127_20109_4 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00581 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 536.0
EH3_k127_20109_5 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 420.0
EH3_k127_20109_6 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 389.0
EH3_k127_20109_7 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 382.0
EH3_k127_20109_8 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00580 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 361.0
EH3_k127_20109_9 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 349.0
EH3_k127_2250300_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.236e-297 919.0
EH3_k127_2250300_1 PFAM amine oxidase - - - 6.047e-196 619.0
EH3_k127_2250300_2 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 533.0
EH3_k127_2250300_3 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 379.0
EH3_k127_2250300_4 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 316.0
EH3_k127_2250300_5 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001255 254.0
EH3_k127_2250300_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 0.000000000000000000000000000000000000000000000006423 176.0
EH3_k127_2250300_7 protein possibly involved in aromatic compounds catabolism K02614 - - 0.00000000000000000000000153 108.0
EH3_k127_2250300_8 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.0000000000000005129 80.0
EH3_k127_225979_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1104.0
EH3_k127_225979_1 DEAD DEAH box helicase domain protein K10896 - - 3.52e-301 941.0
EH3_k127_225979_10 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 350.0
EH3_k127_225979_11 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 312.0
EH3_k127_225979_12 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 302.0
EH3_k127_225979_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 295.0
EH3_k127_225979_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 291.0
EH3_k127_225979_15 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 288.0
EH3_k127_225979_16 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
EH3_k127_225979_17 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008781 262.0
EH3_k127_225979_18 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003193 261.0
EH3_k127_225979_19 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000002218 255.0
EH3_k127_225979_2 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 5.329e-262 821.0
EH3_k127_225979_20 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000003603 211.0
EH3_k127_225979_21 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000003321 198.0
EH3_k127_225979_22 TfuA-like protein - - - 0.000000000000000000000000000000000000000000000121 177.0
EH3_k127_225979_23 hydrolase K04794 - 3.1.1.29 0.0000000000000000000000000000000000000000000004271 173.0
EH3_k127_225979_24 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000000000001751 168.0
EH3_k127_225979_25 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000000000000000007459 155.0
EH3_k127_225979_26 - - - - 0.0000000000000000000000000000000000000004829 151.0
EH3_k127_225979_27 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000000000000000000223 141.0
EH3_k127_225979_28 PFAM molybdopterin biosynthesis MoaE K03635,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.000000000000000000000000000000000009939 139.0
EH3_k127_225979_29 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.00000000000000000000001528 104.0
EH3_k127_225979_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.531e-221 705.0
EH3_k127_225979_30 PDGLE domain K02009 - - 0.0000000000000000000001131 109.0
EH3_k127_225979_31 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000001142 80.0
EH3_k127_225979_32 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000001953 73.0
EH3_k127_225979_4 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 610.0
EH3_k127_225979_5 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 549.0
EH3_k127_225979_6 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 504.0
EH3_k127_225979_7 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 454.0
EH3_k127_225979_8 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 446.0
EH3_k127_225979_9 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 429.0
EH3_k127_2260829_0 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 293.0
EH3_k127_2260829_1 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 291.0
EH3_k127_2260829_2 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001568 262.0
EH3_k127_2260829_3 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000004692 174.0
EH3_k127_2296_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 410.0
EH3_k127_2296_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 284.0
EH3_k127_2296_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000009896 220.0
EH3_k127_2296_3 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000002726 174.0
EH3_k127_2296_4 Helix-turn-helix domain protein K03627 - - 0.0000000000000000000000000000000000000000000003212 171.0
EH3_k127_2306732_0 acid binding OB-fold tRNA helicase-type K07463 - - 3.173e-279 871.0
EH3_k127_2306732_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 417.0
EH3_k127_2306732_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000003851 67.0
EH3_k127_2388780_0 Protein-export membrane protein SecD K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 320.0
EH3_k127_2388780_1 Involved in protein export K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 285.0
EH3_k127_2391425_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 541.0
EH3_k127_2391425_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 518.0
EH3_k127_2391425_2 Domain of unknown function (DUF1743) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 413.0
EH3_k127_2391425_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000331 289.0
EH3_k127_2391425_4 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.00000000000000000000000000000000000000000002867 164.0
EH3_k127_2391425_5 PFAM Radical SAM - - - 0.0000000003163 63.0
EH3_k127_2433557_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 2.391e-289 899.0
EH3_k127_2433557_1 DEAD DEAH box helicase domain protein K03725 - - 1.799e-283 885.0
EH3_k127_2433557_10 ribosomal protein S15 K02956 - - 0.0000000000000000000000000000000000000000000000000000000000000000001141 232.0
EH3_k127_2433557_11 - - - - 0.0000000000000006435 80.0
EH3_k127_2433557_2 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.148e-235 737.0
EH3_k127_2433557_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 553.0
EH3_k127_2433557_4 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 385.0
EH3_k127_2433557_5 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 389.0
EH3_k127_2433557_6 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 295.0
EH3_k127_2433557_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002298 282.0
EH3_k127_2433557_8 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001517 258.0
EH3_k127_2433557_9 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005724 243.0
EH3_k127_2482136_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 5.321e-271 844.0
EH3_k127_2482136_1 AAA-like domain K06915 - - 6.756e-226 711.0
EH3_k127_2482136_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 432.0
EH3_k127_2482136_11 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 420.0
EH3_k127_2482136_12 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 422.0
EH3_k127_2482136_13 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 410.0
EH3_k127_2482136_14 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 313.0
EH3_k127_2482136_15 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 298.0
EH3_k127_2482136_16 cytidyltransferase-related domain K00952 - 2.7.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001583 280.0
EH3_k127_2482136_17 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.0000000000000000000000000000000000000000000000000000000000000008704 222.0
EH3_k127_2482136_18 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000459 198.0
EH3_k127_2482136_19 COG1202 Superfamily II helicase, archaea-specific - - - 0.0000000000000000000000000000000000000000000000000000131 192.0
EH3_k127_2482136_2 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 9.393e-218 680.0
EH3_k127_2482136_20 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000004809 184.0
EH3_k127_2482136_21 - - - - 0.0000000000000000000000000000000000000000000006629 168.0
EH3_k127_2482136_22 - - - - 0.0000000000000000000000000000001009 130.0
EH3_k127_2482136_23 - - - - 0.00000000000000000000000001382 111.0
EH3_k127_2482136_24 - - - - 0.0000000000002768 75.0
EH3_k127_2482136_25 - K06868 - 2.5.1.73 0.0000001494 57.0
EH3_k127_2482136_3 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 591.0
EH3_k127_2482136_4 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 558.0
EH3_k127_2482136_5 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 546.0
EH3_k127_2482136_6 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 518.0
EH3_k127_2482136_7 MviN-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 442.0
EH3_k127_2482136_8 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 430.0
EH3_k127_2482136_9 PFAM formate nitrite transporter K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 426.0
EH3_k127_2623652_0 Glycosyl hydrolase family 57 K07405 - 3.2.1.1 2.553e-196 623.0
EH3_k127_2623652_1 Starch synthase catalytic domain - - - 1.544e-194 614.0
EH3_k127_2623652_10 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.000000000000000000000000000000000000000000000000000000000005563 213.0
EH3_k127_2623652_11 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.0000000000000000000000000000000000000000000000000004757 188.0
EH3_k127_2623652_12 PFAM Glycosyl transferase, group 1 K06338,K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000002923 190.0
EH3_k127_2623652_13 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000002981 155.0
EH3_k127_2623652_2 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 608.0
EH3_k127_2623652_3 methanogenesis marker protein 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 440.0
EH3_k127_2623652_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 384.0
EH3_k127_2623652_5 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 374.0
EH3_k127_2623652_6 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 347.0
EH3_k127_2623652_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
EH3_k127_2623652_8 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 293.0
EH3_k127_2623652_9 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
EH3_k127_297807_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 4.028e-264 827.0
EH3_k127_297807_1 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 343.0
EH3_k127_297807_2 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 299.0
EH3_k127_297807_3 PFAM Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000001148 172.0
EH3_k127_297807_4 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.00002263 52.0
EH3_k127_3111207_0 PFAM SufBD protein K07033 - - 8.018e-194 613.0
EH3_k127_3111207_1 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 295.0
EH3_k127_3111207_2 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001169 273.0
EH3_k127_3111207_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001597 264.0
EH3_k127_3345263_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 6.172e-217 677.0
EH3_k127_3345263_1 - K00960 - 2.7.7.6 0.000000000000000000004757 95.0
EH3_k127_340792_0 Heat shock 70 kDa protein K04043 - - 4.639e-294 914.0
EH3_k127_340792_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.059e-249 773.0
EH3_k127_340792_10 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 373.0
EH3_k127_340792_11 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 369.0
EH3_k127_340792_12 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 346.0
EH3_k127_340792_13 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 349.0
EH3_k127_340792_14 PFAM zinc iron permease K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 323.0
EH3_k127_340792_15 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 319.0
EH3_k127_340792_16 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 301.0
EH3_k127_340792_17 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 295.0
EH3_k127_340792_18 PFAM Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001902 292.0
EH3_k127_340792_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001469 271.0
EH3_k127_340792_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 5.489e-199 631.0
EH3_k127_340792_20 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000468 246.0
EH3_k127_340792_21 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000001524 241.0
EH3_k127_340792_22 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
EH3_k127_340792_23 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000002864 226.0
EH3_k127_340792_24 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000459 198.0
EH3_k127_340792_25 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000003942 190.0
EH3_k127_340792_26 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000003347 188.0
EH3_k127_340792_27 Flavodoxin domain - - - 0.000000000000000000000000000000000000000000000002286 177.0
EH3_k127_340792_28 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000005827 171.0
EH3_k127_340792_29 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000834 171.0
EH3_k127_340792_3 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 531.0
EH3_k127_340792_30 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000000001489 166.0
EH3_k127_340792_31 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000005019 163.0
EH3_k127_340792_32 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000008565 158.0
EH3_k127_340792_33 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000003095 138.0
EH3_k127_340792_34 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.0000000000000000000000000000008669 126.0
EH3_k127_340792_35 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000118 116.0
EH3_k127_340792_36 - - - - 0.00000000000000000000000004073 114.0
EH3_k127_340792_37 PHP domain protein - - - 0.000000000000000000000468 97.0
EH3_k127_340792_38 Protease prsW family - - - 0.00000000000000009652 91.0
EH3_k127_340792_39 - - - - 0.000000004814 60.0
EH3_k127_340792_4 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 510.0
EH3_k127_340792_40 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000007717 57.0
EH3_k127_340792_41 - - - - 0.0000006805 52.0
EH3_k127_340792_42 PBS lyase HEAT-like repeat - - - 0.00006357 53.0
EH3_k127_340792_43 - - - - 0.0001603 46.0
EH3_k127_340792_44 PHP domain protein - - - 0.0006911 42.0
EH3_k127_340792_5 Sodium hydrogen exchanger K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 476.0
EH3_k127_340792_6 Protein of unknown function (DUF1646) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 425.0
EH3_k127_340792_7 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 419.0
EH3_k127_340792_8 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 379.0
EH3_k127_340792_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 385.0
EH3_k127_3436647_0 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 453.0
EH3_k127_3436647_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 439.0
EH3_k127_3436647_10 - - - - 0.0001491 49.0
EH3_k127_3436647_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 429.0
EH3_k127_3436647_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 376.0
EH3_k127_3436647_4 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 357.0
EH3_k127_3436647_5 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 340.0
EH3_k127_3436647_6 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000002279 257.0
EH3_k127_3436647_7 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000003611 239.0
EH3_k127_3436647_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000001635 221.0
EH3_k127_3436647_9 structural constituent of ribosome K02962 - - 0.0000000000000001664 80.0
EH3_k127_3443506_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.131e-254 795.0
EH3_k127_3443506_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 2.174e-196 619.0
EH3_k127_3443506_10 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004031 249.0
EH3_k127_3443506_11 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000002803 231.0
EH3_k127_3443506_12 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000005425 196.0
EH3_k127_3443506_13 Thioredoxin - - - 0.00000000000000000000000000000000000000000004305 164.0
EH3_k127_3443506_14 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000509 147.0
EH3_k127_3443506_15 - K03686 - - 0.00000000000000000002527 91.0
EH3_k127_3443506_2 PFAM glutamate--cysteine ligase, GCS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 436.0
EH3_k127_3443506_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 424.0
EH3_k127_3443506_4 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 405.0
EH3_k127_3443506_5 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 331.0
EH3_k127_3443506_6 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 296.0
EH3_k127_3443506_7 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 296.0
EH3_k127_3443506_8 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 289.0
EH3_k127_3443506_9 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006205 265.0
EH3_k127_3459119_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 595.0
EH3_k127_3459119_1 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 586.0
EH3_k127_3459119_10 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000004699 154.0
EH3_k127_3459119_11 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000216 131.0
EH3_k127_3459119_12 - - - - 0.00000000000000000000000000007631 118.0
EH3_k127_3459119_2 PFAM glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 557.0
EH3_k127_3459119_3 Belongs to the glutamate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 447.0
EH3_k127_3459119_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 435.0
EH3_k127_3459119_5 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 364.0
EH3_k127_3459119_6 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 328.0
EH3_k127_3459119_7 PFAM Amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000008473 226.0
EH3_k127_3459119_8 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000004156 176.0
EH3_k127_3459119_9 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000005761 162.0
EH3_k127_3476934_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 574.0
EH3_k127_3476934_1 - - - - 0.00000000000000000182 91.0
EH3_k127_3725704_0 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 569.0
EH3_k127_3725704_1 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 426.0
EH3_k127_3725704_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 338.0
EH3_k127_3725704_3 Protein phosphatase 2C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000587 246.0
EH3_k127_3725704_4 COG0515 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000003348 176.0
EH3_k127_3725704_5 ABC 3 transport family K09816 - - 0.00000000000000000003988 92.0
EH3_k127_3725704_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000002295 79.0
EH3_k127_3747656_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 526.0
EH3_k127_3747656_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 413.0
EH3_k127_3747656_2 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 364.0
EH3_k127_388507_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 545.0
EH3_k127_388507_1 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
EH3_k127_388507_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004928 258.0
EH3_k127_388507_3 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001694 242.0
EH3_k127_388507_4 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.0000000000000000002648 95.0
EH3_k127_388507_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14107 - - 0.0000000000000007926 79.0
EH3_k127_388507_6 - K14100 - - 0.000000009053 58.0
EH3_k127_4371424_0 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 310.0
EH3_k127_4371424_1 PFAM PEGA domain - - - 0.000000000000000000000000000000000000000000005377 172.0
EH3_k127_4371424_2 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000008345 135.0
EH3_k127_4371424_3 PFAM PQ loop repeat K15383 - - 0.00000000000000000008989 91.0
EH3_k127_4371424_4 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000004013 89.0
EH3_k127_446705_0 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 507.0
EH3_k127_446705_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 505.0
EH3_k127_446705_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 391.0
EH3_k127_446705_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 294.0
EH3_k127_446705_4 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000002733 231.0
EH3_k127_446705_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000004438 193.0
EH3_k127_446705_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000827 181.0
EH3_k127_4479116_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 462.0
EH3_k127_4479116_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 370.0
EH3_k127_4479116_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 368.0
EH3_k127_4488411_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1260.0
EH3_k127_4488411_1 PFAM CBS domain - - - 8.571e-234 732.0
EH3_k127_4488411_10 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000000000000000000000000000005772 224.0
EH3_k127_4488411_11 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000000000000000000000000008761 221.0
EH3_k127_4488411_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000002 170.0
EH3_k127_4488411_13 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000001952 164.0
EH3_k127_4488411_14 Glutaredoxin - - - 0.0000000000000000000000000000001481 125.0
EH3_k127_4488411_15 zinc finger, SWIM - - - 0.000000000000000000000000000004869 122.0
EH3_k127_4488411_16 - - - - 0.000000000000000000000000002976 116.0
EH3_k127_4488411_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000008018 104.0
EH3_k127_4488411_18 - - - - 0.0000000000000004836 85.0
EH3_k127_4488411_19 - - - - 0.0000000000000308 79.0
EH3_k127_4488411_2 ATP-grasp domain K06913 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 425.0
EH3_k127_4488411_20 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000479 67.0
EH3_k127_4488411_21 - - - - 0.0000000002149 65.0
EH3_k127_4488411_3 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
EH3_k127_4488411_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002503 260.0
EH3_k127_4488411_5 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001635 252.0
EH3_k127_4488411_6 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000001595 233.0
EH3_k127_4488411_7 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000000000001011 231.0
EH3_k127_4488411_8 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000001297 233.0
EH3_k127_4488411_9 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000002714 234.0
EH3_k127_4573010_0 DNA polymerase beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 418.0
EH3_k127_4573010_1 PFAM amino acid-binding ACT domain protein K06862 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 318.0
EH3_k127_4573010_2 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 298.0
EH3_k127_4573010_3 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000000001701 241.0
EH3_k127_4573010_4 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000005857 236.0
EH3_k127_4573010_5 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000000000002962 146.0
EH3_k127_4685102_0 Belongs to the MCM family K10726 - - 2.115e-302 941.0
EH3_k127_4685102_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 499.0
EH3_k127_4685102_2 PFAM TatD-related deoxyribonuclease K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 376.0
EH3_k127_4685102_3 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008633 280.0
EH3_k127_4685102_4 pfam nmd3 K07562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007601 258.0
EH3_k127_4685102_5 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000001454 146.0
EH3_k127_4685102_6 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000001558 130.0
EH3_k127_4685102_7 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000008795 112.0
EH3_k127_4685102_8 DEAD DEAH box helicase domain protein K03724 - - 0.0000000000000000000000003091 107.0
EH3_k127_4717127_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 3.266e-244 760.0
EH3_k127_4717127_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 2.962e-219 690.0
EH3_k127_4717127_10 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 405.0
EH3_k127_4717127_11 PFAM Radical SAM domain protein K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 402.0
EH3_k127_4717127_12 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 398.0
EH3_k127_4717127_13 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 385.0
EH3_k127_4717127_14 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 368.0
EH3_k127_4717127_15 PFAM GTP-binding protein HSR1-related K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 366.0
EH3_k127_4717127_16 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 352.0
EH3_k127_4717127_17 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 338.0
EH3_k127_4717127_18 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 335.0
EH3_k127_4717127_19 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 317.0
EH3_k127_4717127_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.007e-219 689.0
EH3_k127_4717127_20 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 291.0
EH3_k127_4717127_21 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 281.0
EH3_k127_4717127_22 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 267.0
EH3_k127_4717127_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002066 262.0
EH3_k127_4717127_24 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000003059 252.0
EH3_k127_4717127_25 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 252.0
EH3_k127_4717127_26 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000001406 234.0
EH3_k127_4717127_27 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000115 228.0
EH3_k127_4717127_28 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000008761 217.0
EH3_k127_4717127_29 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000004732 208.0
EH3_k127_4717127_3 Helix-hairpin-helix domain K02347 - - 3.27e-200 639.0
EH3_k127_4717127_30 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000005535 190.0
EH3_k127_4717127_31 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000000000000000000000000000183 181.0
EH3_k127_4717127_32 Zn-ribbon containing protein K07163 - - 0.000000000000000000000000000000000000000000000001683 176.0
EH3_k127_4717127_33 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000000000000000000004262 166.0
EH3_k127_4717127_34 iron dependent repressor K03709,K04758 - - 0.000000000000000000000000000000008808 135.0
EH3_k127_4717127_35 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000000002023 126.0
EH3_k127_4717127_36 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000000002218 91.0
EH3_k127_4717127_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 560.0
EH3_k127_4717127_5 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 521.0
EH3_k127_4717127_6 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 481.0
EH3_k127_4717127_7 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005254 454.0
EH3_k127_4717127_8 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 447.0
EH3_k127_4717127_9 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 431.0
EH3_k127_4893405_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 1.119e-199 632.0
EH3_k127_4893405_1 PFAM alanine dehydrogenase PNT domain protein K00259,K00324 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1,1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 602.0
EH3_k127_4893405_2 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 607.0
EH3_k127_4893405_3 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000002796 225.0
EH3_k127_4893405_4 COG1246 N-acetylglutamate synthase and related acetyltransferases K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000855 221.0
EH3_k127_4893405_5 PFAM NAD(P) transhydrogenase, beta subunit K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000008148 200.0
EH3_k127_4893405_6 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000001242 169.0
EH3_k127_4893405_7 Transcriptional regulator - - - 0.000000000002051 69.0
EH3_k127_4957742_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.959e-244 758.0
EH3_k127_4957742_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 384.0
EH3_k127_4957742_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 325.0
EH3_k127_4957742_3 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 301.0
EH3_k127_4957742_4 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000009571 215.0
EH3_k127_4957742_5 adenyl ribonucleotide binding - - - 0.0000000000000000000000000000000000000000000001758 173.0
EH3_k127_4957755_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 386.0
EH3_k127_4957755_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 342.0
EH3_k127_4957755_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000003109 253.0
EH3_k127_4960924_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.414e-241 751.0
EH3_k127_4960924_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 520.0
EH3_k127_4960924_10 Protein of unknown function (DUF2953) - - - 0.0000000000008185 77.0
EH3_k127_4960924_11 PFAM Linocin_M18 bacteriocin protein - - - 0.0000000001173 63.0
EH3_k127_4960924_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 514.0
EH3_k127_4960924_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 433.0
EH3_k127_4960924_4 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 417.0
EH3_k127_4960924_5 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001283 247.0
EH3_k127_4960924_6 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
EH3_k127_4960924_7 NADPH-dependent FMN reductase - - - 0.00000000000000000000000001032 110.0
EH3_k127_4960924_8 chorismate mutase K04093 - 5.4.99.5 0.0000000000000000000000002458 109.0
EH3_k127_4960924_9 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000000044 106.0
EH3_k127_5061701_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 490.0
EH3_k127_5061701_1 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 318.0
EH3_k127_5061701_2 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 312.0
EH3_k127_5061701_3 Yip1 domain - - - 0.0000000000000000000000000000000000000000000001489 176.0
EH3_k127_5149401_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1691.0
EH3_k127_5149401_1 Uncharacterized protein conserved in archaea (DUF2114) - - - 4.523e-250 779.0
EH3_k127_5149401_10 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.00000000000000000000000000000000000000000000000001127 183.0
EH3_k127_5149401_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000641 179.0
EH3_k127_5149401_12 Uncharacterised protein family UPF0058 - - - 0.00000000000000000000000000000000000000004523 153.0
EH3_k127_5149401_13 - - - - 0.0000000000000000000000002328 107.0
EH3_k127_5149401_14 Belongs to the UPF0235 family K09131 - - 0.000000000000000006004 87.0
EH3_k127_5149401_2 PFAM Radical SAM domain protein K06937 - - 3.7e-243 758.0
EH3_k127_5149401_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.86e-198 623.0
EH3_k127_5149401_4 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 596.0
EH3_k127_5149401_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 509.0
EH3_k127_5149401_6 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 412.0
EH3_k127_5149401_7 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 390.0
EH3_k127_5149401_8 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 311.0
EH3_k127_5149401_9 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000000000003188 214.0
EH3_k127_5323110_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1021.0
EH3_k127_5323110_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.19e-316 975.0
EH3_k127_5323110_10 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.136e-215 677.0
EH3_k127_5323110_11 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 604.0
EH3_k127_5323110_12 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 581.0
EH3_k127_5323110_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 486.0
EH3_k127_5323110_14 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 467.0
EH3_k127_5323110_15 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 452.0
EH3_k127_5323110_16 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 451.0
EH3_k127_5323110_17 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 345.0
EH3_k127_5323110_18 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 349.0
EH3_k127_5323110_19 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 324.0
EH3_k127_5323110_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 4.413e-268 829.0
EH3_k127_5323110_20 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 331.0
EH3_k127_5323110_21 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 315.0
EH3_k127_5323110_22 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 310.0
EH3_k127_5323110_23 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002314 270.0
EH3_k127_5323110_24 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005744 268.0
EH3_k127_5323110_25 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001598 250.0
EH3_k127_5323110_26 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003677 248.0
EH3_k127_5323110_27 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000002333 228.0
EH3_k127_5323110_28 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000004348 211.0
EH3_k127_5323110_29 PFAM PUA domain containing protein K07575 - - 0.000000000000000000000000000000000000000000000000000000006721 202.0
EH3_k127_5323110_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.065e-246 790.0
EH3_k127_5323110_30 Pfam:DUF552 K09152 - - 0.000000000000000000000000000000000000000000000000000001188 194.0
EH3_k127_5323110_31 ZPR1-related zinc finger protein K06874 - - 0.00000000000000000000000000000000000000000000001166 179.0
EH3_k127_5323110_32 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000002946 171.0
EH3_k127_5323110_33 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000001107 172.0
EH3_k127_5323110_34 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000033 172.0
EH3_k127_5323110_35 - - - - 0.000000000000000000000000000000000000000000001264 169.0
EH3_k127_5323110_36 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000005891 166.0
EH3_k127_5323110_37 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000009692 162.0
EH3_k127_5323110_38 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000000000000000000008273 158.0
EH3_k127_5323110_39 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000000000003237 132.0
EH3_k127_5323110_4 PFAM chaperonin Cpn60 TCP-1 K22447 - - 2.795e-239 751.0
EH3_k127_5323110_40 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000004645 128.0
EH3_k127_5323110_41 Zinc-ribbon containing domain - - - 0.0000000000000000000000000000009335 122.0
EH3_k127_5323110_42 binds to the 23S rRNA K02922 - - 0.000000000000000000000000001677 111.0
EH3_k127_5323110_43 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000000000000003259 111.0
EH3_k127_5323110_44 Transglutaminase-like superfamily - - - 0.000000000000000000000003478 116.0
EH3_k127_5323110_45 - - - - 0.000000000000000000001979 93.0
EH3_k127_5323110_46 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000003336 101.0
EH3_k127_5323110_47 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000213 92.0
EH3_k127_5323110_48 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.0000000000000000006593 89.0
EH3_k127_5323110_49 PFAM Desulfoferrodoxin Dfx domain protein - - - 0.000000000000003514 76.0
EH3_k127_5323110_5 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 1.539e-236 747.0
EH3_k127_5323110_50 SigmaK-factor processing regulatory protein BofA - - - 0.00000000001978 67.0
EH3_k127_5323110_51 - - - - 0.00000003596 63.0
EH3_k127_5323110_52 - - - - 0.000001924 54.0
EH3_k127_5323110_53 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0001187 48.0
EH3_k127_5323110_6 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 9.02e-230 729.0
EH3_k127_5323110_7 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 1.804e-229 728.0
EH3_k127_5323110_8 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.165e-218 691.0
EH3_k127_5323110_9 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 1.563e-216 681.0
EH3_k127_5336205_0 Proton-conducting membrane transporter K05568 - - 1.324e-211 669.0
EH3_k127_5336205_1 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 3.422e-196 618.0
EH3_k127_5336205_10 - - - - 0.000000000000000000000000000000000000004547 151.0
EH3_k127_5336205_11 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000000000000000000000000000007491 140.0
EH3_k127_5336205_12 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000000001091 127.0
EH3_k127_5336205_13 Domain of unknown function (DUF4040) - - - 0.0000000000000000000002097 99.0
EH3_k127_5336205_14 Membrane bound hydrogenase - - - 0.0000000000000000000004137 98.0
EH3_k127_5336205_15 Multiple resistance and pH regulation protein F K05570 - - 0.00000000000000000003474 92.0
EH3_k127_5336205_16 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000002124 53.0
EH3_k127_5336205_2 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 8.301e-196 620.0
EH3_k127_5336205_3 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 381.0
EH3_k127_5336205_4 RNA methylase K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 353.0
EH3_k127_5336205_5 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000007906 244.0
EH3_k127_5336205_6 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000001042 223.0
EH3_k127_5336205_7 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.0000000000000000000000000000000000000000000000000000000000001352 216.0
EH3_k127_5336205_8 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.000000000000000000000000000000000000000000000000001484 185.0
EH3_k127_5336205_9 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.0000000000000000000000000000000000000000000000001835 181.0
EH3_k127_5567182_0 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 438.0
EH3_k127_5567182_1 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 435.0
EH3_k127_5567182_2 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000001103 173.0
EH3_k127_5567182_3 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000001853 158.0
EH3_k127_5578311_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 5.947e-208 665.0
EH3_k127_5578311_1 Rhodanese-like domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 520.0
EH3_k127_5578311_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000005366 158.0
EH3_k127_5578311_11 DNA polymerase activity K02319 - 2.7.7.7 0.0000000000000000000006469 102.0
EH3_k127_5578311_12 - - - - 0.0000001102 58.0
EH3_k127_5578311_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 454.0
EH3_k127_5578311_3 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 434.0
EH3_k127_5578311_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 440.0
EH3_k127_5578311_5 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 425.0
EH3_k127_5578311_6 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 417.0
EH3_k127_5578311_7 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 319.0
EH3_k127_5578311_8 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000365 287.0
EH3_k127_5578311_9 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001701 269.0
EH3_k127_5583724_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 529.0
EH3_k127_5583724_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 445.0
EH3_k127_5583724_2 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 279.0
EH3_k127_5583724_3 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000005447 211.0
EH3_k127_5583724_4 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000009273 180.0
EH3_k127_5583724_5 chorismate mutase K04093 - 5.4.99.5 0.00000000000000000000000003885 112.0
EH3_k127_5589199_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1750.0
EH3_k127_5589199_1 PFAM ABC transporter K00400 - - 1.021e-282 875.0
EH3_k127_5589199_10 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 395.0
EH3_k127_5589199_11 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 382.0
EH3_k127_5589199_12 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 384.0
EH3_k127_5589199_13 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 361.0
EH3_k127_5589199_14 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 357.0
EH3_k127_5589199_15 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 324.0
EH3_k127_5589199_16 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 317.0
EH3_k127_5589199_17 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008059 254.0
EH3_k127_5589199_18 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000001243 246.0
EH3_k127_5589199_19 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001798 232.0
EH3_k127_5589199_2 COG0464 ATPases of the AAA class K13525 - - 1.216e-271 857.0
EH3_k127_5589199_20 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000000000000000000000002441 189.0
EH3_k127_5589199_21 PAS domain - - - 0.0000000000000000000000000000000000000000000000002601 186.0
EH3_k127_5589199_22 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000001214 180.0
EH3_k127_5589199_23 Protein of unknown function (DUF432) K09149 - - 0.000000000000000000000000000000000000000001164 166.0
EH3_k127_5589199_24 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000006069 119.0
EH3_k127_5589199_25 - - - - 0.00000000000000000000003286 106.0
EH3_k127_5589199_26 HEAT repeat - - - 0.00000000000000000002284 98.0
EH3_k127_5589199_27 Histidine kinase-like ATPases - - - 0.000000006471 68.0
EH3_k127_5589199_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 8.149e-208 653.0
EH3_k127_5589199_4 TIGRFAM UbiD family - - - 5.247e-194 612.0
EH3_k127_5589199_5 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 601.0
EH3_k127_5589199_6 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 555.0
EH3_k127_5589199_7 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 537.0
EH3_k127_5589199_8 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 454.0
EH3_k127_5589199_9 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 402.0
EH3_k127_5590092_0 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 415.0
EH3_k127_5590092_1 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 388.0
EH3_k127_5590092_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 373.0
EH3_k127_5590092_3 - - - - 0.0000000000000000000000000000000000000000000000000000000004093 206.0
EH3_k127_5590092_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000005231 154.0
EH3_k127_5590092_5 - - - - 0.00000000000000000000002764 110.0
EH3_k127_5614571_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 484.0
EH3_k127_5614571_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 347.0
EH3_k127_5614571_2 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 301.0
EH3_k127_5614571_3 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000874 226.0
EH3_k127_5614571_4 Pas domain - - - 0.0000000000000000000000000000000000000000000000000000001448 211.0
EH3_k127_5614571_5 - - - - 0.0001621 46.0
EH3_k127_5621758_0 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 483.0
EH3_k127_5621758_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 447.0
EH3_k127_5621758_2 methanogen marker protein 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 287.0
EH3_k127_5621758_3 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000002794 248.0
EH3_k127_5621758_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000001852 119.0
EH3_k127_5621758_5 transcription factor (CBF NF-Y) - - - 0.00000000000000000000000000697 113.0
EH3_k127_5716254_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1313.0
EH3_k127_5716254_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.464e-305 947.0
EH3_k127_5716254_10 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 347.0
EH3_k127_5716254_11 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 345.0
EH3_k127_5716254_12 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 342.0
EH3_k127_5716254_13 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 341.0
EH3_k127_5716254_14 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 338.0
EH3_k127_5716254_15 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 325.0
EH3_k127_5716254_16 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000889 284.0
EH3_k127_5716254_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001865 286.0
EH3_k127_5716254_18 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000251 211.0
EH3_k127_5716254_19 PFAM TrkA-C domain K07228 - - 0.000000000000000000000000000000000000000000000000000000000006819 211.0
EH3_k127_5716254_2 PFAM PilT protein domain protein K06865 - - 9.191e-281 874.0
EH3_k127_5716254_20 - - - - 0.00000000000000000000000000000000000000000000000000000001682 199.0
EH3_k127_5716254_21 - - - - 0.000000000000000000000000000000000000000000000000000000112 210.0
EH3_k127_5716254_22 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000007837 188.0
EH3_k127_5716254_23 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000003666 183.0
EH3_k127_5716254_24 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000000000000000000000000000003412 177.0
EH3_k127_5716254_25 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000006665 183.0
EH3_k127_5716254_26 - - - - 0.000000000000000000000000000000000000000000000002286 183.0
EH3_k127_5716254_27 Roadblock LC7 K07131 - - 0.000000000000000000000000000000000000000000004417 165.0
EH3_k127_5716254_28 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000001098 164.0
EH3_k127_5716254_29 - - - - 0.000000000000000000000000000000000000000006191 161.0
EH3_k127_5716254_3 PFAM type II secretion system protein E K07332 - - 1.105e-280 884.0
EH3_k127_5716254_30 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000002193 158.0
EH3_k127_5716254_31 Protein of unknown function (DUF473) K09135 - - 0.00000000000000000000000000000000004891 138.0
EH3_k127_5716254_32 - K00960 - 2.7.7.6 0.00000000000000000000000000000005234 125.0
EH3_k127_5716254_33 - - - - 0.000000000000000000000000003406 113.0
EH3_k127_5716254_34 Protein of unknown function (DUF2769) - - - 0.00000000000000000000000002823 110.0
EH3_k127_5716254_35 PFAM response regulator receiver K11443 - - 0.00000000000000000000000007932 111.0
EH3_k127_5716254_36 - - - - 0.0000000000000000000001437 105.0
EH3_k127_5716254_37 PFAM peptidase U32 K08303 - - 0.0000000000000000000036 96.0
EH3_k127_5716254_38 E-Z type HEAT repeats - - - 0.000000000005925 70.0
EH3_k127_5716254_39 - - - - 0.00000003724 63.0
EH3_k127_5716254_4 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 459.0
EH3_k127_5716254_40 PFAM Radical SAM domain protein - - - 0.00006711 46.0
EH3_k127_5716254_5 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 428.0
EH3_k127_5716254_6 PFAM ABC transporter related K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 395.0
EH3_k127_5716254_7 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 402.0
EH3_k127_5716254_8 TIGRFAM cell division ATPase MinD K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
EH3_k127_5716254_9 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 371.0
EH3_k127_5756974_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 369.0
EH3_k127_5756974_1 - - - - 0.000000000000000000000000000000000000000006214 159.0
EH3_k127_5756974_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000003721 87.0
EH3_k127_5756974_3 Bacterial transcription activator, effector binding domain - - - 0.000000000000000000512 90.0
EH3_k127_5775728_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 2.801e-275 854.0
EH3_k127_5775728_1 PFAM dihydropteroate synthase, DHPS - - - 4.126e-200 634.0
EH3_k127_5775728_10 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.00000000000000000000000000000000000000000000000000008123 188.0
EH3_k127_5775728_11 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000003565 180.0
EH3_k127_5775728_12 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000004707 135.0
EH3_k127_5775728_13 Protein of unknown function (DUF2769) - - - 0.00000000000000000000003776 103.0
EH3_k127_5775728_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 583.0
EH3_k127_5775728_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 507.0
EH3_k127_5775728_4 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 433.0
EH3_k127_5775728_5 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 374.0
EH3_k127_5775728_6 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 348.0
EH3_k127_5775728_7 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 293.0
EH3_k127_5775728_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009079 279.0
EH3_k127_5775728_9 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000006465 204.0
EH3_k127_5842944_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 493.0
EH3_k127_5842944_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 404.0
EH3_k127_5842944_2 tRNAHis guanylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 299.0
EH3_k127_5842944_3 PFAM PRC-barrel domain - - - 0.00000000000000000000000000000009366 126.0
EH3_k127_6087846_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 3.616e-250 778.0
EH3_k127_6087846_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 539.0
EH3_k127_6087846_2 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 503.0
EH3_k127_6087846_3 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 294.0
EH3_k127_6087846_4 coenzyme F420-reducing hydrogenase, delta subunit K00442 - - 0.000000000000000000000000000000000000000000000000000000000000000000009657 238.0
EH3_k127_616871_0 PFAM Thiolase K00626 - 2.3.1.9 3.175e-208 651.0
EH3_k127_616871_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 583.0
EH3_k127_616871_10 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003823 269.0
EH3_k127_616871_11 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009293 249.0
EH3_k127_616871_12 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000000000000000779 221.0
EH3_k127_616871_13 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000186 213.0
EH3_k127_616871_14 Anaerobic ribonucleoside-triphosphate reductase - - - 0.000000000000000000000000000000000000000000000000000000001282 202.0
EH3_k127_616871_15 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000003228 154.0
EH3_k127_616871_16 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000003061 108.0
EH3_k127_616871_2 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 569.0
EH3_k127_616871_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 552.0
EH3_k127_616871_4 Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 400.0
EH3_k127_616871_5 Cysteine-rich small domain K08260 - 3.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 382.0
EH3_k127_616871_6 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 351.0
EH3_k127_616871_7 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 343.0
EH3_k127_616871_8 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
EH3_k127_616871_9 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 304.0
EH3_k127_6624904_0 Conserved region in glutamate synthase - - - 7.593e-290 895.0
EH3_k127_6624904_1 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 1.819e-229 720.0
EH3_k127_6624904_10 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009692 285.0
EH3_k127_6624904_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002312 278.0
EH3_k127_6624904_12 Ferritin-like domain K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000003624 215.0
EH3_k127_6624904_13 Belongs to the UPF0179 family K09730 - - 0.000000000000000000000000000000000000000000000000000000004689 203.0
EH3_k127_6624904_14 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000000000006846 169.0
EH3_k127_6624904_15 - - - - 0.0000000000000000000000000000000000000000001485 164.0
EH3_k127_6624904_16 Stage II sporulation protein M K06384 - - 0.000000000000000000000000000000000003416 144.0
EH3_k127_6624904_17 protein conserved in archaea K09723 - - 0.0000000000000000000000000000000000831 142.0
EH3_k127_6624904_18 PHP C-terminal domain protein - - - 0.000000000000000000000000000000017 130.0
EH3_k127_6624904_19 metal-binding protein - - - 0.00000000000000000000000006648 109.0
EH3_k127_6624904_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 2.969e-221 694.0
EH3_k127_6624904_20 PFAM Ribosomal protein S27E K02978 - - 0.000000000000000000000001448 103.0
EH3_k127_6624904_21 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000006027 73.0
EH3_k127_6624904_22 - - - - 0.00000003111 57.0
EH3_k127_6624904_3 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 618.0
EH3_k127_6624904_4 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 536.0
EH3_k127_6624904_5 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 476.0
EH3_k127_6624904_6 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 406.0
EH3_k127_6624904_7 Translation initiation factor 2 alpha subunit K03237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 357.0
EH3_k127_6624904_8 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 328.0
EH3_k127_6624904_9 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 296.0
EH3_k127_6663885_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1164.0
EH3_k127_6663885_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1124.0
EH3_k127_6663885_10 TIGRFAM F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 327.0
EH3_k127_6663885_11 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 308.0
EH3_k127_6663885_12 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001786 264.0
EH3_k127_6663885_13 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001044 251.0
EH3_k127_6663885_14 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000000000000000000000000003599 236.0
EH3_k127_6663885_15 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000003722 210.0
EH3_k127_6663885_16 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000008659 168.0
EH3_k127_6663885_18 - - - - 0.00000000000000000000000375 102.0
EH3_k127_6663885_19 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000433 98.0
EH3_k127_6663885_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 7.992e-215 674.0
EH3_k127_6663885_20 - - - - 0.000000000000000005592 89.0
EH3_k127_6663885_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 469.0
EH3_k127_6663885_4 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 465.0
EH3_k127_6663885_5 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 451.0
EH3_k127_6663885_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 417.0
EH3_k127_6663885_7 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 417.0
EH3_k127_6663885_8 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 396.0
EH3_k127_6663885_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 334.0
EH3_k127_6694720_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.403e-245 764.0
EH3_k127_6694720_1 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 334.0
EH3_k127_6694720_2 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000008514 251.0
EH3_k127_6694720_3 TIGRFAM ribosomal protein L30P K02907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003785 243.0
EH3_k127_6694720_4 Integral membrane protein DUF106 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005468 244.0
EH3_k127_6694720_5 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000005656 166.0
EH3_k127_6700856_0 PFAM Beta propeller domain K14475 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 609.0
EH3_k127_6700856_1 membrane K09167 - - 0.000000000000000000000000000000000000000000000009697 177.0
EH3_k127_6715588_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.185e-288 895.0
EH3_k127_6715588_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 1.073e-198 623.0
EH3_k127_6715588_2 B-block binding subunit of TFIIIC - - - 0.0000000000000000000000000000000000000000000004251 168.0
EH3_k127_6715588_3 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000000001682 125.0
EH3_k127_6715588_4 - - - - 0.000000000007302 70.0
EH3_k127_6715588_5 Hsp20/alpha crystallin family K13993 - - 0.00000000004511 70.0
EH3_k127_6747222_0 Domain of unknown function (DUF814) - - - 1.049e-203 652.0
EH3_k127_6747222_1 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 574.0
EH3_k127_6747222_10 RNase L inhibitor, RLI - - - 0.0000000000000000000000003884 108.0
EH3_k127_6747222_11 PFAM YHS domain - - - 0.00000000000009133 72.0
EH3_k127_6747222_12 - - - - 0.00000645 52.0
EH3_k127_6747222_2 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 471.0
EH3_k127_6747222_3 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 400.0
EH3_k127_6747222_4 PFAM metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 295.0
EH3_k127_6747222_5 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000001151 246.0
EH3_k127_6747222_6 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000008194 214.0
EH3_k127_6747222_7 in RNase L inhibitor, RLI K06174 - - 0.0000000000000000000000000000000000000000005575 161.0
EH3_k127_6747222_8 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000007361 160.0
EH3_k127_6747222_9 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.000000000000000000000000000000000005488 143.0
EH3_k127_6782328_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.783e-236 755.0
EH3_k127_6782328_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 408.0
EH3_k127_6782328_2 Protein of unknown function (DUF1648) - - - 0.000000000000000000000000000000000000000000000000000000000001503 218.0
EH3_k127_6782328_3 - - - - 0.000000000000001988 81.0
EH3_k127_6816781_0 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 364.0
EH3_k127_6816781_1 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000299 259.0
EH3_k127_6816781_2 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000007131 221.0
EH3_k127_6816781_3 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000000000000000001858 183.0
EH3_k127_6880143_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 425.0
EH3_k127_6880143_1 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 346.0
EH3_k127_6880143_10 transcription activator, effector binding - - - 0.000000000000000000000000000000000000000000007358 169.0
EH3_k127_6880143_11 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.0000000000000000000000000000000000000002504 155.0
EH3_k127_6880143_12 TIGRFAM C_GCAxxG_C_C family - - - 0.000000000000000000000000001576 117.0
EH3_k127_6880143_13 ABC-2 type transporter K01992 - - 0.0000000000000000001061 90.0
EH3_k127_6880143_15 - - - - 0.000000009442 61.0
EH3_k127_6880143_16 sister chromatid segregation - - - 0.0004807 51.0
EH3_k127_6880143_2 O-methyltransferase K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004286 265.0
EH3_k127_6880143_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002806 248.0
EH3_k127_6880143_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001817 238.0
EH3_k127_6880143_5 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000005562 225.0
EH3_k127_6880143_6 Uncharacterized protein conserved in archaea (DUF2121) - - - 0.00000000000000000000000000000000000000000000000000000025 200.0
EH3_k127_6880143_7 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000000000000000005804 180.0
EH3_k127_6880143_8 - - - - 0.00000000000000000000000000000000000000000000004896 175.0
EH3_k127_6880143_9 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000007339 171.0
EH3_k127_6899851_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1219.0
EH3_k127_6899851_1 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 6.017e-249 777.0
EH3_k127_6899851_10 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002918 253.0
EH3_k127_6899851_11 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000168 214.0
EH3_k127_6899851_12 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000001244 193.0
EH3_k127_6899851_13 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.00000000000000000000000000000000000000000000000000396 186.0
EH3_k127_6899851_14 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000001305 185.0
EH3_k127_6899851_15 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000003534 87.0
EH3_k127_6899851_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.762e-247 775.0
EH3_k127_6899851_3 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 3.17e-212 665.0
EH3_k127_6899851_4 DEAD DEAH box helicase K06877 - - 7.87e-205 649.0
EH3_k127_6899851_5 DNA methylase K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 443.0
EH3_k127_6899851_6 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 378.0
EH3_k127_6899851_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 333.0
EH3_k127_6899851_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003734 281.0
EH3_k127_6899851_9 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 249.0
EH3_k127_702660_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 4.878e-311 963.0
EH3_k127_702660_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.514e-295 915.0
EH3_k127_702660_2 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 340.0
EH3_k127_702660_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 312.0
EH3_k127_702660_4 Belongs to the dCTP deaminase family K01494,K09887 - 3.5.4.13,3.5.4.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 297.0
EH3_k127_702660_5 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000001285 218.0
EH3_k127_702660_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000004192 190.0
EH3_k127_702660_7 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.000000000000000001259 85.0
EH3_k127_702660_8 - - - - 0.000002242 55.0
EH3_k127_7159048_0 peptidyl-tyrosine sulfation - - - 3.151e-259 840.0
EH3_k127_7159048_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 5.162e-231 720.0
EH3_k127_7159048_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 2.118e-227 709.0
EH3_k127_7159048_3 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 602.0
EH3_k127_7159048_4 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 479.0
EH3_k127_7159048_5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 312.0
EH3_k127_7159048_6 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000002708 202.0
EH3_k127_7159048_7 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000000000005094 115.0
EH3_k127_7159048_8 PFAM Transcriptional regulator PadR-like family - - - 0.0000002256 63.0
EH3_k127_7414871_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1553.0
EH3_k127_7414871_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1211.0
EH3_k127_7414871_10 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 402.0
EH3_k127_7414871_11 TIGRFAM cell division ATPase MinD K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 382.0
EH3_k127_7414871_12 PFAM glutamate synthase alpha subunit domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 340.0
EH3_k127_7414871_13 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 335.0
EH3_k127_7414871_14 PHP C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 334.0
EH3_k127_7414871_15 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 310.0
EH3_k127_7414871_16 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 313.0
EH3_k127_7414871_17 transcription termination protein NusA K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000003344 233.0
EH3_k127_7414871_18 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000003805 226.0
EH3_k127_7414871_19 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000008463 162.0
EH3_k127_7414871_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0 1043.0
EH3_k127_7414871_20 protein N-acetylglucosaminyltransferase activity K12600 - - 0.000000000000000000000000000000000000000006594 166.0
EH3_k127_7414871_21 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.0000000000000000000000000000001242 126.0
EH3_k127_7414871_22 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000000000000000007633 124.0
EH3_k127_7414871_23 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000001263 122.0
EH3_k127_7414871_24 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.0000000000000000000002879 98.0
EH3_k127_7414871_25 Tetratricopeptide repeat K12600 - - 0.000000000000000004115 93.0
EH3_k127_7414871_26 - - - - 0.000000000000000004176 92.0
EH3_k127_7414871_27 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000008043 84.0
EH3_k127_7414871_28 Roadblock LC7 family protein K06945,K07131 - - 0.000000000004664 71.0
EH3_k127_7414871_29 - - - - 0.000000006403 64.0
EH3_k127_7414871_3 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 9.495e-300 923.0
EH3_k127_7414871_30 - - - - 0.000006097 50.0
EH3_k127_7414871_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 596.0
EH3_k127_7414871_5 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 578.0
EH3_k127_7414871_6 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 580.0
EH3_k127_7414871_7 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 512.0
EH3_k127_7414871_8 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 491.0
EH3_k127_7414871_9 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 413.0
EH3_k127_7749769_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 1.033e-259 818.0
EH3_k127_7749769_1 PFAM peptidase U32 K08303 - - 4.963e-204 666.0
EH3_k127_7749769_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 523.0
EH3_k127_7749769_3 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000001014 173.0
EH3_k127_7749769_4 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000004153 162.0
EH3_k127_7749769_5 Protein of unknown function, DUF255 K06888 - - 0.0000000000001622 74.0
EH3_k127_7921321_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0 1043.0
EH3_k127_7921321_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.478e-250 781.0
EH3_k127_7921321_10 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 539.0
EH3_k127_7921321_11 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 488.0
EH3_k127_7921321_12 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 466.0
EH3_k127_7921321_13 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 418.0
EH3_k127_7921321_14 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 413.0
EH3_k127_7921321_15 signal transduction protein with CBS domains K07744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 410.0
EH3_k127_7921321_16 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 401.0
EH3_k127_7921321_17 TIGRFAM small GTP-binding protein K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 396.0
EH3_k127_7921321_18 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 379.0
EH3_k127_7921321_19 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 363.0
EH3_k127_7921321_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 5.975e-223 703.0
EH3_k127_7921321_20 PFAM oxidoreductase nitrogenase, component 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 355.0
EH3_k127_7921321_21 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 339.0
EH3_k127_7921321_22 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 327.0
EH3_k127_7921321_23 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001507 284.0
EH3_k127_7921321_24 ABC-type tungstate transport system, periplasmic component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005316 281.0
EH3_k127_7921321_25 TIGRFAM formate dehydrogenase family accessory protein FdhD K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007067 274.0
EH3_k127_7921321_26 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000001398 244.0
EH3_k127_7921321_27 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000008757 228.0
EH3_k127_7921321_28 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000002946 228.0
EH3_k127_7921321_29 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000001401 210.0
EH3_k127_7921321_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.905e-194 609.0
EH3_k127_7921321_30 Domain of unknown function (DUF1890) - - - 0.000000000000000000000000000000000000000000000000003197 185.0
EH3_k127_7921321_31 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000005384 177.0
EH3_k127_7921321_32 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000001951 166.0
EH3_k127_7921321_33 - - - - 0.000000000000000000000000000000001421 133.0
EH3_k127_7921321_34 Domain of unknown function (DUF1894) - - - 0.0000000000000000000000000000004643 124.0
EH3_k127_7921321_35 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000002182 105.0
EH3_k127_7921321_36 Transcriptional regulator K07108 - - 0.0000000000000000000001128 101.0
EH3_k127_7921321_37 rubredoxin - - - 0.0000000000000000000002626 98.0
EH3_k127_7921321_38 - - - - 0.000000000000000000000728 101.0
EH3_k127_7921321_39 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000001635 91.0
EH3_k127_7921321_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 596.0
EH3_k127_7921321_40 PRC-barrel domain protein - - - 0.0000000000000000005264 89.0
EH3_k127_7921321_5 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 582.0
EH3_k127_7921321_6 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 578.0
EH3_k127_7921321_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 564.0
EH3_k127_7921321_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 557.0
EH3_k127_7921321_9 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 543.0
EH3_k127_7936326_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1065.0
EH3_k127_7936326_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 2.185e-244 769.0
EH3_k127_7936326_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 565.0
EH3_k127_7936326_3 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 408.0
EH3_k127_7936326_4 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 374.0
EH3_k127_7936326_5 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000003229 85.0
EH3_k127_7936326_6 - - - - 0.000000000000001731 79.0
EH3_k127_7993497_0 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000007832 194.0
EH3_k127_7993497_1 - - - - 0.000000000000000000000000000000003617 132.0
EH3_k127_7993497_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000008087 139.0
EH3_k127_7993497_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000001055 123.0
EH3_k127_7993497_4 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0002003 45.0
EH3_k127_8040098_0 KH, type 1, domain K07041 - - 0.0 1074.0
EH3_k127_8040098_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 1.748e-293 910.0
EH3_k127_8040098_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000009246 74.0
EH3_k127_8040098_11 Involved in protein export. The function of the beta subunit is - GO:0003674,GO:0005085,GO:0005086,GO:0005488,GO:0005515,GO:0008150,GO:0019899,GO:0051020,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000006237 72.0
EH3_k127_8040098_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 415.0
EH3_k127_8040098_3 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 384.0
EH3_k127_8040098_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 307.0
EH3_k127_8040098_5 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 314.0
EH3_k127_8040098_6 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 307.0
EH3_k127_8040098_7 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000001425 235.0
EH3_k127_8040098_8 COG0589 Universal stress protein UspA and related nucleotide-binding - - - 0.000000000000000000000000000000000000000000007506 168.0
EH3_k127_8040098_9 - - - - 0.000000000000000000000000000006971 122.0
EH3_k127_8057100_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1424.0
EH3_k127_8057100_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.11e-309 960.0
EH3_k127_8057100_10 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000009725 209.0
EH3_k127_8057100_11 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000001334 205.0
EH3_k127_8057100_12 Ferrous iron transport B domain protein K04759 - - 0.000000000000000000000000000000000000000000000000000004394 194.0
EH3_k127_8057100_13 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000007236 187.0
EH3_k127_8057100_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000003005 188.0
EH3_k127_8057100_15 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000001178 185.0
EH3_k127_8057100_16 AMP binding - - - 0.0000000000000000000000000000000000000000000008394 176.0
EH3_k127_8057100_17 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000001162 173.0
EH3_k127_8057100_18 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000001375 173.0
EH3_k127_8057100_19 ATP synthase subunit K K02124 - - 0.0000000000000000000000000000000000000000002896 163.0
EH3_k127_8057100_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.025e-247 776.0
EH3_k127_8057100_20 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000002553 164.0
EH3_k127_8057100_21 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000000000000004061 138.0
EH3_k127_8057100_22 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000003713 122.0
EH3_k127_8057100_23 ThiS family K03636 - - 0.0000000000000000000000000002161 117.0
EH3_k127_8057100_24 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000002965 116.0
EH3_k127_8057100_25 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000002892 103.0
EH3_k127_8057100_26 Ferredoxin K05337 - - 0.0000000000000000009461 89.0
EH3_k127_8057100_28 PFAM ABC-2 type transporter K01992 - - 0.00000000000000002497 86.0
EH3_k127_8057100_29 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000265 83.0
EH3_k127_8057100_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.555e-213 668.0
EH3_k127_8057100_30 - - - - 0.000000000000003758 82.0
EH3_k127_8057100_31 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.000000000003047 70.0
EH3_k127_8057100_32 PFAM ABC-2 type transporter K01992 - - 0.00000000001001 66.0
EH3_k127_8057100_33 PspC domain K03973 - - 0.0000000489 56.0
EH3_k127_8057100_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 599.0
EH3_k127_8057100_5 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 391.0
EH3_k127_8057100_6 V-type ATP synthase, subunit I K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 347.0
EH3_k127_8057100_7 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 310.0
EH3_k127_8057100_8 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 304.0
EH3_k127_8057100_9 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 324.0
EH3_k127_8112004_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.366e-224 704.0
EH3_k127_8112004_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 368.0
EH3_k127_8112004_10 Involved in protein export K03074 - - 0.0000000000001351 73.0
EH3_k127_8112004_2 PFAM ABC transporter K16786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000279 242.0
EH3_k127_8112004_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005794 230.0
EH3_k127_8112004_4 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.00000000000000000000000000000000000000000000000000000000005895 207.0
EH3_k127_8112004_5 PFAM BioY protein K03523 - - 0.000000000000000000000000000000000000000000000000004778 187.0
EH3_k127_8112004_6 PFAM ABC transporter related K02068,K03529,K06166,K16786,K16787 - 2.7.8.37 0.0000000000000000000000000000000000000009908 152.0
EH3_k127_8112004_7 Protein of unknown function (DUF2551) - - - 0.000000000000000000000000000000000009123 138.0
EH3_k127_8112004_8 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000000001116 134.0
EH3_k127_8112004_9 - - - - 0.0000000000000000002349 91.0
EH3_k127_8330508_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 5.988e-213 668.0
EH3_k127_8330508_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 526.0
EH3_k127_8330508_10 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000000000000000008375 196.0
EH3_k127_8330508_11 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000000000000000000001513 171.0
EH3_k127_8330508_12 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000000000000000000000000000000000638 155.0
EH3_k127_8330508_13 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000000000000000006646 147.0
EH3_k127_8330508_14 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000000000000000000007642 145.0
EH3_k127_8330508_15 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000000000000002469 134.0
EH3_k127_8330508_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000157 118.0
EH3_k127_8330508_17 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000005367 107.0
EH3_k127_8330508_18 PBS lyase HEAT-like repeat - - - 0.00000000000000000000004221 111.0
EH3_k127_8330508_19 CRS1_YhbY K07574 - - 0.0000000000000000000005069 97.0
EH3_k127_8330508_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 472.0
EH3_k127_8330508_20 structural constituent of ribosome K02924 - - 0.0000000000000000002417 89.0
EH3_k127_8330508_21 PFAM Ribosomal LX protein K02944 - - 0.000000000008388 69.0
EH3_k127_8330508_22 COG3364 Zn-ribbon containing protein K07163 - - 0.0003928 52.0
EH3_k127_8330508_3 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 435.0
EH3_k127_8330508_4 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 312.0
EH3_k127_8330508_5 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001309 274.0
EH3_k127_8330508_6 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003595 273.0
EH3_k127_8330508_7 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008208 271.0
EH3_k127_8330508_8 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000000000000000000000000000000000000000000000009749 261.0
EH3_k127_8330508_9 PFAM methyltransferase small K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000001175 209.0
EH3_k127_8661433_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.792e-296 927.0
EH3_k127_8661433_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.039e-290 907.0
EH3_k127_8661433_10 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 586.0
EH3_k127_8661433_11 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 556.0
EH3_k127_8661433_12 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 552.0
EH3_k127_8661433_13 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 542.0
EH3_k127_8661433_14 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 540.0
EH3_k127_8661433_15 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 526.0
EH3_k127_8661433_16 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 502.0
EH3_k127_8661433_17 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 500.0
EH3_k127_8661433_18 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 496.0
EH3_k127_8661433_19 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 481.0
EH3_k127_8661433_2 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 1.498e-276 869.0
EH3_k127_8661433_20 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 452.0
EH3_k127_8661433_21 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 421.0
EH3_k127_8661433_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 387.0
EH3_k127_8661433_23 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 368.0
EH3_k127_8661433_24 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 338.0
EH3_k127_8661433_25 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 321.0
EH3_k127_8661433_26 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 307.0
EH3_k127_8661433_27 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 308.0
EH3_k127_8661433_28 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001194 273.0
EH3_k127_8661433_29 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000899 261.0
EH3_k127_8661433_3 SMART Elongator protein 3 MiaB NifB - - - 1.333e-259 812.0
EH3_k127_8661433_30 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
EH3_k127_8661433_31 KH domain protein K06961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001148 256.0
EH3_k127_8661433_32 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001355 256.0
EH3_k127_8661433_33 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000018 251.0
EH3_k127_8661433_34 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000001527 244.0
EH3_k127_8661433_35 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000002279 236.0
EH3_k127_8661433_36 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000000000000000000000000000000000000000000000000000009965 229.0
EH3_k127_8661433_37 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000001663 222.0
EH3_k127_8661433_38 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.0000000000000000000000000000000000000000000000000000000000000004146 225.0
EH3_k127_8661433_39 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000000000000000000000000213 218.0
EH3_k127_8661433_4 Involved in regulation of DNA replication K10725 - - 9.056e-209 655.0
EH3_k127_8661433_40 PFAM Ribonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000004836 212.0
EH3_k127_8661433_41 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000005935 208.0
EH3_k127_8661433_42 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000002565 196.0
EH3_k127_8661433_43 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000001294 199.0
EH3_k127_8661433_44 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000001468 196.0
EH3_k127_8661433_45 SMART Excinuclease ABC, C subunit - - - 0.000000000000000000000000000000000000000000001596 168.0
EH3_k127_8661433_46 Peptidase family M23 - - - 0.000000000000000000000000000000000000001892 153.0
EH3_k127_8661433_47 Flavodoxin - - - 0.00000000000000000000000000000000000001708 149.0
EH3_k127_8661433_48 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000000000000000000000000000000006349 146.0
EH3_k127_8661433_49 nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000000000000001826 136.0
EH3_k127_8661433_5 PFAM aminotransferase class V - - - 5.186e-203 639.0
EH3_k127_8661433_50 Domain of unknown function (DUF1805) - - - 0.000000000000000000000000000007997 121.0
EH3_k127_8661433_51 protein conserved in archaea - - - 0.0000000000000000000000000001726 117.0
EH3_k127_8661433_52 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000000000000000000000003515 115.0
EH3_k127_8661433_53 nucleic acid binding OB-fold tRNA helicase-type - - - 0.00000000000000000000000000155 115.0
EH3_k127_8661433_54 - - - - 0.00000000000000000000002222 111.0
EH3_k127_8661433_55 - - - - 0.0000000000000000000003586 103.0
EH3_k127_8661433_56 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000000000001284 95.0
EH3_k127_8661433_57 transcriptional regulators K03724 - - 0.00000000000000000006381 91.0
EH3_k127_8661433_58 Belongs to the UPF0434 family - - - 0.0000000000000000002154 88.0
EH3_k127_8661433_59 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000001069 86.0
EH3_k127_8661433_6 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 9.53e-202 640.0
EH3_k127_8661433_60 COG0457 FOG TPR repeat - - - 0.00001405 51.0
EH3_k127_8661433_61 - - - - 0.0003797 46.0
EH3_k127_8661433_7 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 599.0
EH3_k127_8661433_8 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 589.0
EH3_k127_8661433_9 PFAM Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 584.0