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Overview

ID MAG01217
Name GDHHQS2_bin.30
Sample SMP0032
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Nitrososphaeria
Order Nitrososphaerales
Family Nitrososphaeraceae
Genus Nitrososphaera
Species Nitrososphaera sp035760305
Assembly information
Completeness (%) 73.47
Contamination (%) 0.45
GC content (%) 56.0
N50 (bp) 9,502
Genome size (bp) 1,211,986

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1304

Gene name Description KEGG GOs EC E-value Score Sequence
GDHHQS2_k127_1008854_0 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 502.0
GDHHQS2_k127_1008854_1 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 359.0
GDHHQS2_k127_1008854_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 326.0
GDHHQS2_k127_1008854_3 Transcriptional regulator K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003442 273.0
GDHHQS2_k127_1008854_4 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000000000000000000000000000000001201 213.0
GDHHQS2_k127_1008854_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000004466 177.0
GDHHQS2_k127_1008854_6 Belongs to the SUI1 family K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003863 124.0
GDHHQS2_k127_1015743_0 methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 480.0
GDHHQS2_k127_1015743_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 374.0
GDHHQS2_k127_1015743_2 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000005067 170.0
GDHHQS2_k127_1015743_5 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K00595,K02006,K02191 - 2.1.1.132,2.1.1.196 0.00000000000000000000000000000000000000002839 158.0
GDHHQS2_k127_1015743_7 - - - - 0.00000000000002307 75.0
GDHHQS2_k127_1015743_8 - - - - 0.00000000003795 72.0
GDHHQS2_k127_1015743_9 SpoU rRNA Methylase family - - - 0.0000000003963 63.0
GDHHQS2_k127_1068957_0 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 7.028e-301 932.0
GDHHQS2_k127_1068957_1 Peptidase dimerisation domain - - - 3.468e-241 751.0
GDHHQS2_k127_1068957_10 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000001312 129.0
GDHHQS2_k127_1068957_11 - - - - 0.0000000000000000000001932 101.0
GDHHQS2_k127_1068957_2 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 558.0
GDHHQS2_k127_1068957_3 TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 499.0
GDHHQS2_k127_1068957_4 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 396.0
GDHHQS2_k127_1068957_5 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 364.0
GDHHQS2_k127_1068957_6 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 352.0
GDHHQS2_k127_1068957_7 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000002571 234.0
GDHHQS2_k127_1068957_9 Succinyl-CoA ligase like flavodoxin domain K18593 - - 0.00000000000000000000000000000000000000001167 158.0
GDHHQS2_k127_108007_0 DNA polymerase K02319 - 2.7.7.7 8.487e-217 677.0
GDHHQS2_k127_108007_1 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 511.0
GDHHQS2_k127_108007_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.00000000000000077 77.0
GDHHQS2_k127_1115989_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 2.939e-309 957.0
GDHHQS2_k127_1115989_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 507.0
GDHHQS2_k127_1115989_2 PFAM NurA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 440.0
GDHHQS2_k127_112501_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 2.715e-253 787.0
GDHHQS2_k127_112501_1 Radical SAM K04069 - 1.97.1.4 1.163e-198 622.0
GDHHQS2_k127_112501_11 - - - - 0.00000000000000000000184 94.0
GDHHQS2_k127_112501_12 - - - - 0.000000000000000000007743 94.0
GDHHQS2_k127_112501_13 response regulator, receiver - - - 0.00000000000000000165 89.0
GDHHQS2_k127_112501_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 438.0
GDHHQS2_k127_112501_3 Archaeal ammonia monooxygenase subunit A (AmoA) K10944 - 1.14.18.3,1.14.99.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 434.0
GDHHQS2_k127_112501_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K05934 - 2.1.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 398.0
GDHHQS2_k127_112501_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 373.0
GDHHQS2_k127_112501_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 285.0
GDHHQS2_k127_112501_7 - - - - 0.000000000000000000000000000000000000000000000000009082 181.0
GDHHQS2_k127_112501_8 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.0000000000000000000000000000000000006088 142.0
GDHHQS2_k127_112501_9 RNA polymerase Rpb3/Rpb11 dimerisation domain K03056 - 2.7.7.6 0.0000000000000000000000000000000002519 133.0
GDHHQS2_k127_1148146_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 1.5e-322 998.0
GDHHQS2_k127_1148146_1 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 329.0
GDHHQS2_k127_1148146_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007225 281.0
GDHHQS2_k127_1148146_3 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000002163 195.0
GDHHQS2_k127_1148146_4 - - - - 0.00002283 49.0
GDHHQS2_k127_1193870_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 465.0
GDHHQS2_k127_1193870_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 406.0
GDHHQS2_k127_1193870_2 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 304.0
GDHHQS2_k127_1193870_3 Met-10+ like-protein K15429 - 2.1.1.228 0.00000000000000000000000000000003082 126.0
GDHHQS2_k127_1292498_0 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 552.0
GDHHQS2_k127_1292498_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000001205 231.0
GDHHQS2_k127_1292498_2 Heavy-metal-associated domain K01533 - 3.6.3.4 0.00000000000000000000000000000003741 126.0
GDHHQS2_k127_1292498_3 - - - - 0.0000000000000000000000000003745 115.0
GDHHQS2_k127_1304987_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 595.0
GDHHQS2_k127_1304987_1 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 510.0
GDHHQS2_k127_1304987_10 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000004168 60.0
GDHHQS2_k127_1304987_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 296.0
GDHHQS2_k127_1304987_3 ATP corrinoid adenosyltransferase K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 296.0
GDHHQS2_k127_1304987_4 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001253 224.0
GDHHQS2_k127_1304987_6 - - - - 0.000000000000000000000000000000003391 134.0
GDHHQS2_k127_1304987_7 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000000000000123 98.0
GDHHQS2_k127_1304987_8 glycosyl transferase, family 2 - - - 0.000000000000000001959 95.0
GDHHQS2_k127_1304987_9 Translation initiation factor 2, alpha subunit K03237 - - 0.00000000000004175 73.0
GDHHQS2_k127_1318785_0 DEAD DEAH box helicase K05592 - 3.6.4.13 6.594e-200 630.0
GDHHQS2_k127_1318785_1 factor TFIIB K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 552.0
GDHHQS2_k127_1318785_2 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 366.0
GDHHQS2_k127_1318785_3 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 317.0
GDHHQS2_k127_1318785_4 segregation and condensation protein K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 292.0
GDHHQS2_k127_1318785_5 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000000000000000000000000000000000008021 206.0
GDHHQS2_k127_1318785_7 - - - - 0.000000000000000000000000000000000000000000000133 172.0
GDHHQS2_k127_1318785_8 SRP19 protein K03105 - - 0.000000000000000000000000000000000000000000005177 164.0
GDHHQS2_k127_1318785_9 RNA-binding protein involved in rRNA processing K07569 - - 0.000000000000000000000000000001635 123.0
GDHHQS2_k127_1498021_0 Glycosyl transferase family group 2 - - - 4.627e-291 908.0
GDHHQS2_k127_1498021_1 PFAM regulatory protein, ArsR - - - 1.056e-280 873.0
GDHHQS2_k127_1498021_10 Binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001732 249.0
GDHHQS2_k127_1498021_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000035 236.0
GDHHQS2_k127_1498021_12 - - - - 0.000000000000000000000000000000000000000001209 157.0
GDHHQS2_k127_1498021_13 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000003874 139.0
GDHHQS2_k127_1498021_14 ribosomal protein K02912 - - 0.000000000000000000000000000005737 121.0
GDHHQS2_k127_1498021_15 IMP dehydrogenase activity - - - 0.00000000000000000235 85.0
GDHHQS2_k127_1498021_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.533e-198 626.0
GDHHQS2_k127_1498021_3 ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 529.0
GDHHQS2_k127_1498021_4 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 412.0
GDHHQS2_k127_1498021_5 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 383.0
GDHHQS2_k127_1498021_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 336.0
GDHHQS2_k127_1498021_7 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 326.0
GDHHQS2_k127_1498021_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 293.0
GDHHQS2_k127_1498021_9 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002813 275.0
GDHHQS2_k127_170958_0 synthetase (class II) K01880 - 6.1.1.14 5.852e-272 843.0
GDHHQS2_k127_170958_1 Major Facilitator Superfamily - - - 3.008e-219 689.0
GDHHQS2_k127_170958_10 - - - - 0.0000000000000000000000000000000000000000000001345 168.0
GDHHQS2_k127_170958_12 SnoaL-like domain - - - 0.00002496 49.0
GDHHQS2_k127_170958_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 1.849e-218 685.0
GDHHQS2_k127_170958_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 2.412e-217 681.0
GDHHQS2_k127_170958_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 607.0
GDHHQS2_k127_170958_5 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 357.0
GDHHQS2_k127_170958_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 295.0
GDHHQS2_k127_170958_8 PFAM Methyltransferase type K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007522 244.0
GDHHQS2_k127_1732928_0 COG0668 Small-conductance mechanosensitive channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 409.0
GDHHQS2_k127_1732928_1 PFAM UDP-N-acetylglucosamine 2-epimerase K01791 GO:0003674,GO:0003824,GO:0008761,GO:0016853,GO:0016854,GO:0016857 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000008169 259.0
GDHHQS2_k127_1732928_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000001938 225.0
GDHHQS2_k127_1732928_4 glycosyl transferase family 2 - - - 0.00000000000000000000006141 110.0
GDHHQS2_k127_1732928_5 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000004716 54.0
GDHHQS2_k127_1748817_0 cation diffusion facilitator family transporter - - - 1.259e-194 617.0
GDHHQS2_k127_1748817_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 477.0
GDHHQS2_k127_1748817_10 PFAM response regulator receiver - - - 0.00000000002564 69.0
GDHHQS2_k127_1748817_2 Translin family K07477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 314.0
GDHHQS2_k127_1748817_3 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 299.0
GDHHQS2_k127_1748817_4 Subtilase family K01342 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 293.0
GDHHQS2_k127_1748817_5 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 254.0
GDHHQS2_k127_1748817_6 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01115 - 3.1.4.4 0.0000000000000000000000000000000000001154 159.0
GDHHQS2_k127_1748817_7 - - - - 0.000000000000000000000000000001422 123.0
GDHHQS2_k127_1748817_8 - - - - 0.0000000000000000000002261 106.0
GDHHQS2_k127_1748817_9 response regulator, receiver K07668,K07669 - - 0.000000000000000000004181 98.0
GDHHQS2_k127_178254_0 fumarate reductase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.0 1020.0
GDHHQS2_k127_178254_1 HMGL-like K01649 - 2.3.3.13 7.193e-230 715.0
GDHHQS2_k127_178254_2 argininosuccinate lyase K01755 - 4.3.2.1 5.202e-201 636.0
GDHHQS2_k127_178254_3 Lysine biosynthesis K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 471.0
GDHHQS2_k127_178254_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 435.0
GDHHQS2_k127_178254_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006407 274.0
GDHHQS2_k127_178254_6 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000000000000000000000000008327 193.0
GDHHQS2_k127_178254_7 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000000000000000000000000000000000001219 168.0
GDHHQS2_k127_178254_9 lysine biosynthesis protein LysW K05826 - - 0.00000000000000000000000005556 107.0
GDHHQS2_k127_1805362_0 FeS assembly protein SufB K09014 - - 2.426e-294 904.0
GDHHQS2_k127_1805362_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 6.136e-247 765.0
GDHHQS2_k127_1805362_10 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000000000000003571 166.0
GDHHQS2_k127_1805362_11 of nitrite reductase and ring-hydroxylating K05710 - - 0.0000000000000000000000000000000000000000006232 158.0
GDHHQS2_k127_1805362_12 - - - - 0.00000000000000000000000000000000000001182 146.0
GDHHQS2_k127_1805362_13 mttA/Hcf106 family K03116 - - 0.0000000000000000000000000000000003096 134.0
GDHHQS2_k127_1805362_2 FeS assembly protein SufD K09014,K09015 - - 1.248e-233 730.0
GDHHQS2_k127_1805362_3 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 470.0
GDHHQS2_k127_1805362_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 405.0
GDHHQS2_k127_1805362_5 protein (ATP-grasp superfamily) K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 366.0
GDHHQS2_k127_1805362_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 359.0
GDHHQS2_k127_1805362_7 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 295.0
GDHHQS2_k127_1805362_8 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006471 259.0
GDHHQS2_k127_1805362_9 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000001182 221.0
GDHHQS2_k127_182992_0 Belongs to the RtcB family K14415 - 6.5.1.3 4.953e-274 848.0
GDHHQS2_k127_182992_1 adenylosuccinate lyase K01756 - 4.3.2.2 1.035e-232 727.0
GDHHQS2_k127_182992_2 D-glucuronyl C5-epimerase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 376.0
GDHHQS2_k127_182992_3 - - - - 0.00000000000000001106 83.0
GDHHQS2_k127_1891827_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.714e-293 904.0
GDHHQS2_k127_1891827_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 305.0
GDHHQS2_k127_1891827_2 Cytidylyltransferase-like K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001134 274.0
GDHHQS2_k127_1899526_0 Phosphate uptake regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 308.0
GDHHQS2_k127_1899526_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001449 250.0
GDHHQS2_k127_1899526_2 Patch-forming domain C2 of tRNA-guanine transglycosylase K07398 - - 0.0000000000000000000000000000000000000000000000000000000000000000003799 234.0
GDHHQS2_k127_1899526_3 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000000000000000000000000000004451 180.0
GDHHQS2_k127_1899526_4 H subunit K02107 - - 0.000000000000000000000000000000000001461 143.0
GDHHQS2_k127_1990871_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1313.0
GDHHQS2_k127_1990871_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) - - - 1.788e-211 660.0
GDHHQS2_k127_1990871_10 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000000000000000000000000000000000000002022 179.0
GDHHQS2_k127_1990871_11 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000000000000000000006825 126.0
GDHHQS2_k127_1990871_2 Radical SAM K18285 - 2.5.1.120 2.297e-209 653.0
GDHHQS2_k127_1990871_3 Nucleotidyltransferase domain K07076 - - 4.037e-204 648.0
GDHHQS2_k127_1990871_4 UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 505.0
GDHHQS2_k127_1990871_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 417.0
GDHHQS2_k127_1990871_6 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 407.0
GDHHQS2_k127_1990871_7 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008222 292.0
GDHHQS2_k127_1990871_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000356 262.0
GDHHQS2_k127_1990871_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001579 228.0
GDHHQS2_k127_2001050_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0 1135.0
GDHHQS2_k127_2001050_1 protein (ATP-grasp superfamily) K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 399.0
GDHHQS2_k127_2001050_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 331.0
GDHHQS2_k127_2001050_3 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
GDHHQS2_k127_2001050_4 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000009946 222.0
GDHHQS2_k127_2001050_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000001318 181.0
GDHHQS2_k127_2001050_6 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000003933 168.0
GDHHQS2_k127_2001050_7 Transcriptional regulator - - - 0.00000000000000003544 83.0
GDHHQS2_k127_2001050_9 - - - - 0.000007295 55.0
GDHHQS2_k127_205965_0 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641 - 2.3.3.10 2.526e-271 838.0
GDHHQS2_k127_205965_1 AhpC/TSA family - - - 2.798e-247 771.0
GDHHQS2_k127_205965_10 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000002818 143.0
GDHHQS2_k127_205965_12 - - - - 0.0000001252 58.0
GDHHQS2_k127_205965_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 495.0
GDHHQS2_k127_205965_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 428.0
GDHHQS2_k127_205965_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 379.0
GDHHQS2_k127_205965_5 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 376.0
GDHHQS2_k127_205965_7 - - - - 0.0000000000000000000000000000000000000000000000000000001744 196.0
GDHHQS2_k127_205965_9 Domain of unknown function (DUF2024) - - - 0.0000000000000000000000000000000000000000000005034 167.0
GDHHQS2_k127_2083912_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006407 240.0
GDHHQS2_k127_2083912_2 tRNA pseudouridine synthase K06176 - 5.4.99.27 0.000000000000000000000000000000004443 131.0
GDHHQS2_k127_2083912_3 - - - - 0.00000000000000000000000000000007135 136.0
GDHHQS2_k127_2083912_4 - - - - 0.0000000000000000000345 94.0
GDHHQS2_k127_2083912_5 Transcriptional regulator - - - 0.0000000000000000001901 91.0
GDHHQS2_k127_2083912_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000284 74.0
GDHHQS2_k127_2083912_7 - - - - 0.000000000006706 66.0
GDHHQS2_k127_2083912_8 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.000004514 51.0
GDHHQS2_k127_2085628_0 TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 417.0
GDHHQS2_k127_2085628_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000421 257.0
GDHHQS2_k127_2085628_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 244.0
GDHHQS2_k127_2085628_3 NADH ubiquinone oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000001061 212.0
GDHHQS2_k127_2085628_5 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000009833 120.0
GDHHQS2_k127_210510_0 hydroxymethylglutaryl-CoA reductase (NADPH) activity K00021 - 1.1.1.34 4.217e-210 663.0
GDHHQS2_k127_210510_1 UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 452.0
GDHHQS2_k127_210510_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 359.0
GDHHQS2_k127_210510_3 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000000000000000000000000001753 213.0
GDHHQS2_k127_21271_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 546.0
GDHHQS2_k127_21271_1 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 441.0
GDHHQS2_k127_21271_10 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000000000000000000000000000000005314 197.0
GDHHQS2_k127_21271_11 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000000000000000000000000000006927 192.0
GDHHQS2_k127_21271_12 ribosomal protein K02883 - - 0.000000000000000000000000000000000000000000000000001139 184.0
GDHHQS2_k127_21271_13 - - - - 0.0000000000000000000000000000000000000000003472 159.0
GDHHQS2_k127_21271_14 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000001086 158.0
GDHHQS2_k127_21271_15 Ribosomal L37ae protein family K02921 - - 0.00000000000000000000000000000000005605 134.0
GDHHQS2_k127_21271_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 434.0
GDHHQS2_k127_21271_3 DNA-directed RNA polymerase, alpha subunit 40 kD subunit K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 409.0
GDHHQS2_k127_21271_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 403.0
GDHHQS2_k127_21271_5 ERCC4 domain K10848 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 349.0
GDHHQS2_k127_21271_6 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 348.0
GDHHQS2_k127_21271_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 341.0
GDHHQS2_k127_21271_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001957 250.0
GDHHQS2_k127_21271_9 ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000202 204.0
GDHHQS2_k127_2163265_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 6.75e-237 736.0
GDHHQS2_k127_2163265_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 361.0
GDHHQS2_k127_2163265_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000008858 128.0
GDHHQS2_k127_2171028_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1366.0
GDHHQS2_k127_2171028_1 CBS domain K03498 - - 1.5e-281 878.0
GDHHQS2_k127_2171028_10 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 377.0
GDHHQS2_k127_2171028_11 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 366.0
GDHHQS2_k127_2171028_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 329.0
GDHHQS2_k127_2171028_13 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 323.0
GDHHQS2_k127_2171028_14 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 330.0
GDHHQS2_k127_2171028_15 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 319.0
GDHHQS2_k127_2171028_16 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 317.0
GDHHQS2_k127_2171028_17 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 309.0
GDHHQS2_k127_2171028_18 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
GDHHQS2_k127_2171028_19 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000002269 190.0
GDHHQS2_k127_2171028_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.033e-271 840.0
GDHHQS2_k127_2171028_20 - - - - 0.00000000000000000000000000000000000000000000001583 175.0
GDHHQS2_k127_2171028_21 membrane - - - 0.000000000000000000000000000000000000000000009422 172.0
GDHHQS2_k127_2171028_22 - - - - 0.000000000000000000000000000004649 122.0
GDHHQS2_k127_2171028_23 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000000000000009454 117.0
GDHHQS2_k127_2171028_26 - - - - 0.000000000000003962 90.0
GDHHQS2_k127_2171028_29 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000001474 57.0
GDHHQS2_k127_2171028_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01581,K01586,K13747 - 4.1.1.17,4.1.1.20,4.1.1.96 2.97e-255 790.0
GDHHQS2_k127_2171028_30 - - - - 0.000005984 53.0
GDHHQS2_k127_2171028_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 585.0
GDHHQS2_k127_2171028_5 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 467.0
GDHHQS2_k127_2171028_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 459.0
GDHHQS2_k127_2171028_8 flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 420.0
GDHHQS2_k127_2171028_9 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 417.0
GDHHQS2_k127_2188125_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 1.634e-248 771.0
GDHHQS2_k127_2188125_1 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 8.815e-203 639.0
GDHHQS2_k127_2188125_10 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.00000000000000000002516 94.0
GDHHQS2_k127_2188125_11 - - - - 0.00000000000000000002993 91.0
GDHHQS2_k127_2188125_12 - - - - 0.00000000000000005955 82.0
GDHHQS2_k127_2188125_13 COG NOG14600 non supervised orthologous group - - - 0.0000000000000002207 85.0
GDHHQS2_k127_2188125_16 Sulfotransferase family - - - 0.00000000005234 69.0
GDHHQS2_k127_2188125_2 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 499.0
GDHHQS2_k127_2188125_3 Tubulin/FtsZ family, GTPase domain K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 411.0
GDHHQS2_k127_2188125_4 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008488 253.0
GDHHQS2_k127_2188125_6 F5/8 type C domain - - - 0.000000000000000000000000000000000000000000000227 180.0
GDHHQS2_k127_2188125_7 Belongs to the ribosomal protein L31e family K02910 - - 0.000000000000000000000000000000000000000000001064 168.0
GDHHQS2_k127_2188125_9 Flavin reductase like domain - - - 0.00000000000000000000000005312 119.0
GDHHQS2_k127_2220263_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1872.0
GDHHQS2_k127_2220263_1 ThiF family K21029 - 2.7.7.80 5.094e-239 744.0
GDHHQS2_k127_2220263_10 small metal-binding protein - - - 0.00000000000001386 74.0
GDHHQS2_k127_2220263_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 6.117e-238 738.0
GDHHQS2_k127_2220263_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 1.45e-215 675.0
GDHHQS2_k127_2220263_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 411.0
GDHHQS2_k127_2220263_5 - - - - 0.00000000000000000000000000000000000000000000000000000000001069 211.0
GDHHQS2_k127_2220263_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000000000006225 205.0
GDHHQS2_k127_2220263_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000000000001786 196.0
GDHHQS2_k127_2220263_8 - - - - 0.00000000000000000000000000000000000000005113 155.0
GDHHQS2_k127_2220263_9 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000002935 134.0
GDHHQS2_k127_2249308_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1207.0
GDHHQS2_k127_2249308_1 restriction endonuclease K03546,K06915,K07448 - - 2.222e-259 809.0
GDHHQS2_k127_2249308_10 Transcriptional regulator - - - 0.000000000000007162 78.0
GDHHQS2_k127_2249308_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 555.0
GDHHQS2_k127_2249308_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 364.0
GDHHQS2_k127_2249308_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 366.0
GDHHQS2_k127_2249308_5 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000000000000000000000000000001333 267.0
GDHHQS2_k127_2249308_6 Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity K08096 - 3.5.4.29 0.00000000000000000000000000000000000000000000000000000000000000000000000009249 255.0
GDHHQS2_k127_2249308_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000001086 158.0
GDHHQS2_k127_2323469_0 Cytochrome b subunit of the bc complex K00412 - - 9.446e-275 852.0
GDHHQS2_k127_2323469_1 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 582.0
GDHHQS2_k127_2323469_2 diphthine synthase K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 515.0
GDHHQS2_k127_2323469_3 low-complexity proteins - - - 0.0000000000000000000000000000000000000000000000000000000000002743 216.0
GDHHQS2_k127_2323469_4 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00000000000000000000000000000000000000000000000001226 184.0
GDHHQS2_k127_2323469_5 - - - - 0.00000000000000000000000000000000000000000000002192 173.0
GDHHQS2_k127_2323469_6 COG0723 Rieske Fe-S protein K15878 - - 0.0000000003781 69.0
GDHHQS2_k127_2424664_0 DnaJ molecular chaperone homology domain K03686 - - 0.000000000000000000000000000000000000000000000000000001372 194.0
GDHHQS2_k127_2424664_1 - - - - 0.0000000000000000000000000000000000000000000000000000352 191.0
GDHHQS2_k127_2424664_2 ATP synthase (F/14-kDa) subunit K02122 - - 0.0000000000000000000000000000000000000000000001844 169.0
GDHHQS2_k127_2424664_3 Polyketide cyclase dehydrase - - - 0.0000000000000000000000000000000000000000004675 161.0
GDHHQS2_k127_2424664_5 carbon-nitrogen ligase activity, with glutamine as amido-N-donor - - - 0.000000000004794 68.0
GDHHQS2_k127_2424664_7 beta-galactosidase activity - - - 0.0002277 51.0
GDHHQS2_k127_2462692_0 NOSIC (NUC001) domain K14564 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 458.0
GDHHQS2_k127_2462692_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 454.0
GDHHQS2_k127_2462692_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003987 274.0
GDHHQS2_k127_2462692_3 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
GDHHQS2_k127_2597233_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000000000000000000000000005178 190.0
GDHHQS2_k127_2597233_1 LmbE homologs - - - 0.000000000000000000000000000000000000000000001879 173.0
GDHHQS2_k127_2597233_2 Hexapeptide repeat of succinyl-transferase K02536 - 2.3.1.191 0.00000000000000000000000000000000000000002272 165.0
GDHHQS2_k127_2597233_3 PFAM Glycosyl transferase family 2 K00752 - 2.4.1.212 0.0000002354 59.0
GDHHQS2_k127_2603240_0 Histone acetyltransferase K07739 - 2.3.1.48 2.907e-274 850.0
GDHHQS2_k127_2603240_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 573.0
GDHHQS2_k127_2603240_2 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000021 203.0
GDHHQS2_k127_2603240_3 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000001108 124.0
GDHHQS2_k127_2641609_0 FAD linked - - - 3.239e-214 677.0
GDHHQS2_k127_2641609_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 9.464e-200 626.0
GDHHQS2_k127_2641609_10 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000000000004961 107.0
GDHHQS2_k127_2641609_11 - - - - 0.0000000003843 68.0
GDHHQS2_k127_2641609_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 580.0
GDHHQS2_k127_2641609_3 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 395.0
GDHHQS2_k127_2641609_4 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 379.0
GDHHQS2_k127_2641609_5 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 355.0
GDHHQS2_k127_2641609_6 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003991 268.0
GDHHQS2_k127_2641609_7 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000001654 203.0
GDHHQS2_k127_2641609_8 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000000000000000000000000000000000002891 213.0
GDHHQS2_k127_2641609_9 - - - - 0.000000000000000000000000000000000000001343 148.0
GDHHQS2_k127_26744_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1134.0
GDHHQS2_k127_26744_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.931e-274 847.0
GDHHQS2_k127_26744_11 Transcriptional regulator - - - 0.000000001124 63.0
GDHHQS2_k127_26744_2 GTPase of unknown function C-terminal K06942 - - 2.842e-237 736.0
GDHHQS2_k127_26744_3 Mannosyl-3-phosphoglycerate synthase K05947 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.217 8.358e-210 657.0
GDHHQS2_k127_26744_4 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 464.0
GDHHQS2_k127_26744_5 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000004144 249.0
GDHHQS2_k127_26744_6 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000000000002376 205.0
GDHHQS2_k127_26744_7 - - - - 0.000000000000000000000000000000000000009116 147.0
GDHHQS2_k127_26744_8 - - - - 0.000000000000000000000000000000000005813 140.0
GDHHQS2_k127_271127_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1444.0
GDHHQS2_k127_271127_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1082.0
GDHHQS2_k127_271127_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00313 - - 0.0 1018.0
GDHHQS2_k127_271127_3 Electron transfer flavoprotein domain K03522 - - 4.175e-198 623.0
GDHHQS2_k127_271127_4 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 467.0
GDHHQS2_k127_271127_5 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 331.0
GDHHQS2_k127_271127_6 HD domain K00951,K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 302.0
GDHHQS2_k127_2746781_0 CBS domain K03498 - - 5.876e-219 698.0
GDHHQS2_k127_2746781_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 492.0
GDHHQS2_k127_2746781_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 342.0
GDHHQS2_k127_2746781_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 340.0
GDHHQS2_k127_2746781_5 Pfam:DUF385 - - - 0.00000000000000000000000000005398 121.0
GDHHQS2_k127_27536_0 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 554.0
GDHHQS2_k127_27536_1 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 404.0
GDHHQS2_k127_27536_10 - - - - 0.00000000000000000000000000000000000000006768 158.0
GDHHQS2_k127_27536_11 Transcriptional regulator - - - 0.00000000000000000000000000000000000001039 147.0
GDHHQS2_k127_27536_12 FUN14 family - - - 0.000000000000000000000000000000000667 133.0
GDHHQS2_k127_27536_13 response regulator, receiver - - - 0.00000000000000000000001024 104.0
GDHHQS2_k127_27536_17 - - - - 0.000000232 53.0
GDHHQS2_k127_27536_18 Transcriptional regulator - - - 0.0000008271 54.0
GDHHQS2_k127_27536_2 Required for chromosome condensation and partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 349.0
GDHHQS2_k127_27536_3 PFAM regulatory protein TetR K03577,K18939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 304.0
GDHHQS2_k127_27536_4 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 254.0
GDHHQS2_k127_27536_6 peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000003001 206.0
GDHHQS2_k127_27536_7 RNase H K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000002372 171.0
GDHHQS2_k127_27536_8 - - - - 0.0000000000000000000000000000000000000000007055 160.0
GDHHQS2_k127_275400_0 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 400.0
GDHHQS2_k127_275400_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 369.0
GDHHQS2_k127_275400_2 Domain of unknown function (DUF929) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 317.0
GDHHQS2_k127_275400_3 ribosomal protein K02866 - - 0.000000000000000000000000002222 112.0
GDHHQS2_k127_2792152_0 Enoyl-(Acyl carrier protein) reductase - - - 7.132e-302 934.0
GDHHQS2_k127_2792152_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 8.729e-285 890.0
GDHHQS2_k127_2792152_10 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 358.0
GDHHQS2_k127_2792152_11 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 342.0
GDHHQS2_k127_2792152_12 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 339.0
GDHHQS2_k127_2792152_13 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 310.0
GDHHQS2_k127_2792152_14 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 300.0
GDHHQS2_k127_2792152_15 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 254.0
GDHHQS2_k127_2792152_16 PUA domain K07575 - - 0.0000000000000000000000000000000000000000000000000000000000004569 214.0
GDHHQS2_k127_2792152_18 - - - - 0.000000000000000000000000000000000000000002366 159.0
GDHHQS2_k127_2792152_19 - - - - 0.0000000000000000000000000000000000004904 145.0
GDHHQS2_k127_2792152_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - 3.671e-266 827.0
GDHHQS2_k127_2792152_21 - - - - 0.000000000000001413 80.0
GDHHQS2_k127_2792152_22 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000001956 77.0
GDHHQS2_k127_2792152_23 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000009395 75.0
GDHHQS2_k127_2792152_24 - - - - 0.0000000000000959 74.0
GDHHQS2_k127_2792152_27 copper ion binding - - - 0.00000005622 61.0
GDHHQS2_k127_2792152_3 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 2.492e-225 705.0
GDHHQS2_k127_2792152_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 1.74e-201 634.0
GDHHQS2_k127_2792152_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 6.364e-198 619.0
GDHHQS2_k127_2792152_6 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 612.0
GDHHQS2_k127_2792152_7 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 577.0
GDHHQS2_k127_2792152_8 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 522.0
GDHHQS2_k127_2792152_9 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 378.0
GDHHQS2_k127_2802779_0 methylase K00590 - 2.1.1.113 4.528e-197 619.0
GDHHQS2_k127_2802779_1 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 536.0
GDHHQS2_k127_2802779_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 479.0
GDHHQS2_k127_2802779_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 443.0
GDHHQS2_k127_2802779_4 TIGRFAM phosphate ABC transporter K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 404.0
GDHHQS2_k127_2802779_5 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 359.0
GDHHQS2_k127_2845209_0 Peptidase family M3 K08602 - - 1.298e-294 913.0
GDHHQS2_k127_2845209_1 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 453.0
GDHHQS2_k127_2845209_2 Na -dependent transporter K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 368.0
GDHHQS2_k127_2845209_3 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000000000000003958 96.0
GDHHQS2_k127_2867470_0 Radical SAM K11781 - 2.5.1.77 1.684e-233 726.0
GDHHQS2_k127_2867470_1 Radical SAM K11780 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 586.0
GDHHQS2_k127_2867470_10 Transcriptional regulator - - - 0.0000000000000000000000000000000000001554 143.0
GDHHQS2_k127_2867470_12 Universal stress protein - - - 0.00000000000000000000000000000000008806 138.0
GDHHQS2_k127_2867470_13 - - - - 0.00000000000000000000000000007044 123.0
GDHHQS2_k127_2867470_15 Probable cobalt transporter subunit (CbtB) - - - 0.0000000000000000003202 88.0
GDHHQS2_k127_2867470_16 Iron-binding zinc finger CDGSH type K05710 - - 0.0000000000000000006816 87.0
GDHHQS2_k127_2867470_18 ligase activity K00666,K03892 - - 0.0007219 50.0
GDHHQS2_k127_2867470_2 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 563.0
GDHHQS2_k127_2867470_3 PFAM Alanine dehydrogenase PNT K00259,K00324 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1,1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 552.0
GDHHQS2_k127_2867470_4 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 501.0
GDHHQS2_k127_2867470_5 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 385.0
GDHHQS2_k127_2867470_6 Probable cobalt transporter subunit (CbtA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 298.0
GDHHQS2_k127_2867470_7 Domain of unknown function (DUF4443) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003261 276.0
GDHHQS2_k127_2867470_8 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000349 218.0
GDHHQS2_k127_2867470_9 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000004849 193.0
GDHHQS2_k127_2899436_0 DHHA1 domain K07463 - - 3.551e-251 784.0
GDHHQS2_k127_2899436_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 560.0
GDHHQS2_k127_2899436_2 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 537.0
GDHHQS2_k127_2899436_3 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007282 273.0
GDHHQS2_k127_2899436_4 ribosomal protein K02956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007732 239.0
GDHHQS2_k127_2899436_5 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000002916 182.0
GDHHQS2_k127_2899436_6 - - - - 0.000000000000000000000000000000000000000000855 158.0
GDHHQS2_k127_2899436_7 - - - - 0.0000000000000000000001391 101.0
GDHHQS2_k127_2899436_9 Bacterial PH domain - - - 0.0000003245 57.0
GDHHQS2_k127_2925892_0 TIGRFAM excinuclease ABC, C subunit K03703 - - 3.693e-243 763.0
GDHHQS2_k127_2925892_1 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 529.0
GDHHQS2_k127_2925892_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 470.0
GDHHQS2_k127_2931375_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 6.825e-274 848.0
GDHHQS2_k127_2931375_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665,K06883 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 492.0
GDHHQS2_k127_2931375_2 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000007772 206.0
GDHHQS2_k127_2931375_4 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000007144 161.0
GDHHQS2_k127_2931375_5 restriction endonuclease K03546,K06915,K07448 - - 0.0000000000000000000000000000000000000000434 152.0
GDHHQS2_k127_2931375_8 Lrp/AsnC ligand binding domain - - - 0.00000000000006231 74.0
GDHHQS2_k127_2931375_9 Archaeal Type IV pilin, N-terminal - - - 0.000009844 59.0
GDHHQS2_k127_2956415_0 Vinylacetyl-CoA Delta-isomerase K14534 - 4.2.1.120,5.3.3.3 4.554e-289 892.0
GDHHQS2_k127_2956415_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 602.0
GDHHQS2_k127_2956415_10 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000001104 194.0
GDHHQS2_k127_2956415_11 - - - - 0.000000000000000000000000000000000000000000000000007118 194.0
GDHHQS2_k127_2956415_2 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 557.0
GDHHQS2_k127_2956415_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 353.0
GDHHQS2_k127_2956415_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 337.0
GDHHQS2_k127_2956415_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004851 274.0
GDHHQS2_k127_2956415_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001696 252.0
GDHHQS2_k127_2956415_7 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000004321 242.0
GDHHQS2_k127_2956415_8 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000001047 228.0
GDHHQS2_k127_2956415_9 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
GDHHQS2_k127_2979181_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 2e-323 1006.0
GDHHQS2_k127_2979181_1 methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 552.0
GDHHQS2_k127_2979181_2 Cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 386.0
GDHHQS2_k127_2979181_3 COG1335 Amidases related to nicotinamidase K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 337.0
GDHHQS2_k127_2979181_6 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000001003 162.0
GDHHQS2_k127_2979181_7 - - - - 0.0000000000000002433 85.0
GDHHQS2_k127_2980375_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 6.482e-255 794.0
GDHHQS2_k127_2980375_10 ABC transporter K02041 - 3.6.3.28 0.00000000000000000000000000000000000000002849 161.0
GDHHQS2_k127_2980375_11 - - - - 0.000000000000000000000000000000000000000276 150.0
GDHHQS2_k127_2980375_2 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 413.0
GDHHQS2_k127_2980375_3 PFAM Like-Sm ribonucleoprotein, core - - - 0.00000000000000000000000000000000000000000000000000000000000000000005793 233.0
GDHHQS2_k127_2980375_4 NADH ubiquinone oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000009257 218.0
GDHHQS2_k127_2980375_5 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000003678 213.0
GDHHQS2_k127_2980375_6 - - - - 0.000000000000000000000000000000000000000000000000000000000007702 212.0
GDHHQS2_k127_2980375_7 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000003236 194.0
GDHHQS2_k127_2980375_8 phosphonate ABC transporter, inner membrane subunit K02042 - - 0.000000000000000000000000000000000000000000000005028 181.0
GDHHQS2_k127_2980375_9 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000006456 170.0
GDHHQS2_k127_3018098_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.992e-249 775.0
GDHHQS2_k127_3018098_1 Cysteine desulfurase K04487 - 2.8.1.7 1.208e-195 615.0
GDHHQS2_k127_3018098_10 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000004024 243.0
GDHHQS2_k127_3018098_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006259 224.0
GDHHQS2_k127_3018098_12 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000002515 181.0
GDHHQS2_k127_3018098_13 membrane - - - 0.00000000000000000000000000000000000000000000001585 173.0
GDHHQS2_k127_3018098_14 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000007964 152.0
GDHHQS2_k127_3018098_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 571.0
GDHHQS2_k127_3018098_3 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 530.0
GDHHQS2_k127_3018098_4 tRNA methyl transferase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 422.0
GDHHQS2_k127_3018098_5 Belongs to the universal ribosomal protein uS5 family K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 374.0
GDHHQS2_k127_3018098_6 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 361.0
GDHHQS2_k127_3018098_7 biotin carboxyl carrier K00627,K01571,K15037,K18605 - 2.3.1.12,4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 301.0
GDHHQS2_k127_3018098_8 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 301.0
GDHHQS2_k127_3018098_9 ribosomal protein K02907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001614 258.0
GDHHQS2_k127_301878_0 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 567.0
GDHHQS2_k127_301878_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 562.0
GDHHQS2_k127_301878_2 Domain of unknown function (DUF1802) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005614 279.0
GDHHQS2_k127_301878_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001071 258.0
GDHHQS2_k127_301878_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008326 249.0
GDHHQS2_k127_301878_6 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000005289 161.0
GDHHQS2_k127_301878_7 - - - - 0.0000000000000000000000000000000000002756 148.0
GDHHQS2_k127_301878_8 Chlorite dismutase - - - 0.00000000000000000000007796 98.0
GDHHQS2_k127_3120311_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1415.0
GDHHQS2_k127_3120311_1 Protein tyrosine kinase - - - 0.0001261 53.0
GDHHQS2_k127_3182544_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 0.0 1824.0
GDHHQS2_k127_3182544_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.067e-280 878.0
GDHHQS2_k127_3182544_11 - - - - 0.000000000000000000000000007592 111.0
GDHHQS2_k127_3182544_13 COG1522 Transcriptional regulators - - - 0.0000000000000001699 81.0
GDHHQS2_k127_3182544_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 5.864e-276 861.0
GDHHQS2_k127_3182544_3 AAA domain (Cdc48 subfamily) - - - 4.145e-228 710.0
GDHHQS2_k127_3182544_4 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 572.0
GDHHQS2_k127_3182544_5 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 466.0
GDHHQS2_k127_3182544_6 Phosphoglycolate phosphatase K22223 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055 411.0
GDHHQS2_k127_3182544_7 conserved protein implicated in secretion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 294.0
GDHHQS2_k127_3182544_8 - - - - 0.00000000000000000000000000000000000000000000000000001792 192.0
GDHHQS2_k127_3182544_9 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000007589 154.0
GDHHQS2_k127_3184837_0 Large family of predicted nucleotide-binding domains K06865 - - 3.349e-316 976.0
GDHHQS2_k127_3184837_1 Protein of unknown function (DUF1512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 552.0
GDHHQS2_k127_3184837_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 467.0
GDHHQS2_k127_3184837_3 Peptidase M10A and M12B matrixin and adamalysin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000831 280.0
GDHHQS2_k127_3184837_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000005183 194.0
GDHHQS2_k127_3184837_5 iron dependent repressor - - - 0.000000000000000000000000000000000000000415 149.0
GDHHQS2_k127_3184837_6 metalloendopeptidase activity - - - 0.0000000000000000000005317 97.0
GDHHQS2_k127_3184872_0 Ammonium Transporter K03320 - - 2.394e-231 724.0
GDHHQS2_k127_3184872_1 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 598.0
GDHHQS2_k127_3184872_13 - K06193 - - 0.00000002047 56.0
GDHHQS2_k127_3184872_2 Sodium hydrogen exchanger K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 541.0
GDHHQS2_k127_3184872_3 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 407.0
GDHHQS2_k127_3184872_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 398.0
GDHHQS2_k127_3184872_5 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 381.0
GDHHQS2_k127_3184872_6 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000003367 227.0
GDHHQS2_k127_3184872_7 Ribonuclease K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000165 164.0
GDHHQS2_k127_3184872_8 COG2002 Regulators of stationary sporulation gene expression - - - 0.000000000000000000000000000000000000000008597 155.0
GDHHQS2_k127_3235869_0 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 570.0
GDHHQS2_k127_3235869_1 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 559.0
GDHHQS2_k127_3235869_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 557.0
GDHHQS2_k127_3235869_3 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 550.0
GDHHQS2_k127_3235869_4 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 471.0
GDHHQS2_k127_3235869_5 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 408.0
GDHHQS2_k127_3235869_7 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000008634 140.0
GDHHQS2_k127_3235869_8 - - - - 0.0000000000000000000000001425 109.0
GDHHQS2_k127_3298509_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 442.0
GDHHQS2_k127_3298509_1 ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 327.0
GDHHQS2_k127_3298509_2 Cytidylyltransferase-like K02201 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000007523 216.0
GDHHQS2_k127_3298509_3 - - - - 0.000000000000000000000000000000000000000000000000000000004536 200.0
GDHHQS2_k127_3298509_4 - - - - 0.00000000000000000000000000000000000547 138.0
GDHHQS2_k127_3336973_0 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 358.0
GDHHQS2_k127_3336973_1 PFAM Cupin 2, conserved barrel domain protein K11312 - - 0.000000000000000000000000000000000000000000000000000005706 192.0
GDHHQS2_k127_3336973_2 ribosomal protein K02962 - - 0.000000000000000000000000002276 112.0
GDHHQS2_k127_3336973_3 transcription factor (CBF NF-Y) - - - 0.000000000000000000000001393 110.0
GDHHQS2_k127_3336973_4 - - - - 0.0000000000000474 75.0
GDHHQS2_k127_3361820_0 LOR SDH bifunctional - - - 3.575e-225 704.0
GDHHQS2_k127_3361820_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 548.0
GDHHQS2_k127_3361820_10 response regulator, receiver - - - 0.00000000000000000001761 95.0
GDHHQS2_k127_3361820_11 zinc finger - - - 0.0000000000000009001 77.0
GDHHQS2_k127_3361820_2 methanogenesis marker protein 1 K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 447.0
GDHHQS2_k127_3361820_3 PFAM TfuA domain protein, core - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 319.0
GDHHQS2_k127_3361820_4 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 320.0
GDHHQS2_k127_3361820_5 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 283.0
GDHHQS2_k127_3361820_6 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000001215 214.0
GDHHQS2_k127_3361820_7 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000005708 206.0
GDHHQS2_k127_3361820_8 - - - - 0.000000000000000000000000000000000000000000000000002104 183.0
GDHHQS2_k127_3715940_0 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 3.22e-222 689.0
GDHHQS2_k127_3715940_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 6.198e-216 683.0
GDHHQS2_k127_3715940_2 Tyrosine--tRNA ligase K01866 - 6.1.1.1 3.333e-195 612.0
GDHHQS2_k127_3715940_3 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 489.0
GDHHQS2_k127_3715940_4 Lysine biosynthesis K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 486.0
GDHHQS2_k127_3715940_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000001132 214.0
GDHHQS2_k127_3715940_6 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000005339 155.0
GDHHQS2_k127_3715940_7 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000001887 156.0
GDHHQS2_k127_3715940_8 lysine biosynthesis protein LysW K05826 - - 0.000000000000000000000001205 105.0
GDHHQS2_k127_3715940_9 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000001872 88.0
GDHHQS2_k127_3725500_0 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 583.0
GDHHQS2_k127_3725500_1 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000137 267.0
GDHHQS2_k127_3725500_2 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000000000000000000007694 140.0
GDHHQS2_k127_3725500_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000000000000000000000001313 132.0
GDHHQS2_k127_3733456_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 3.69e-281 869.0
GDHHQS2_k127_3733456_1 phosphohydrolase (DHH superfamily) K07097 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 496.0
GDHHQS2_k127_3733456_10 - - - - 0.000000000000000000000000000000000000000000000002629 177.0
GDHHQS2_k127_3733456_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000000000000000000000009215 107.0
GDHHQS2_k127_3733456_12 Zinc finger, C2H2 type - - - 0.00000000000000000000001696 105.0
GDHHQS2_k127_3733456_13 Transcriptional regulator - - - 0.0000000000000009668 79.0
GDHHQS2_k127_3733456_2 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 462.0
GDHHQS2_k127_3733456_3 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 396.0
GDHHQS2_k127_3733456_4 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091,K01838,K07025 - 3.1.3.18,5.4.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000002073 247.0
GDHHQS2_k127_3733456_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000001056 205.0
GDHHQS2_k127_3733456_6 - - - - 0.000000000000000000000000000000000000000000000000000000002357 202.0
GDHHQS2_k127_3733456_8 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000006146 185.0
GDHHQS2_k127_3733456_9 Pyruvate phosphate dikinase K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000002285 180.0
GDHHQS2_k127_3770656_0 Sulfite reductase K00392 - 1.8.7.1 0.0 1036.0
GDHHQS2_k127_3770656_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 437.0
GDHHQS2_k127_3770656_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 304.0
GDHHQS2_k127_3770656_3 Belongs to the UPF0201 family K09736 - - 0.0000000000000000000000000000000000000000000000000000000000001481 213.0
GDHHQS2_k127_3797974_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 488.0
GDHHQS2_k127_3797974_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 367.0
GDHHQS2_k127_3797974_2 xylanase chitin deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000002297 192.0
GDHHQS2_k127_3797974_3 RNA binding K07581 - - 0.00000000000000000000000000000000000000000000003448 173.0
GDHHQS2_k127_3797974_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000001142 83.0
GDHHQS2_k127_3797974_6 cyclase dehydrase - - - 0.00000001641 62.0
GDHHQS2_k127_3820237_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.0 1038.0
GDHHQS2_k127_3820237_1 Winged helix-turn-helix - - - 0.0000000000000000000000000000000000343 136.0
GDHHQS2_k127_3820237_2 - - - - 0.000000000000000000000000001618 112.0
GDHHQS2_k127_3820237_3 - - - - 0.00000000000001935 74.0
GDHHQS2_k127_3858572_0 Subtilase family - - - 0.0 1651.0
GDHHQS2_k127_3858572_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0 1001.0
GDHHQS2_k127_3858572_10 Binds to the 23S rRNA K02896 - - 0.00000000000000000000000000000000005439 134.0
GDHHQS2_k127_3858572_11 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000000002023 126.0
GDHHQS2_k127_3858572_12 PFAM TCP-1 cpn60 chaperonin family K22447 - - 0.000000000000000000000000000007774 119.0
GDHHQS2_k127_3858572_13 Major Facilitator Superfamily - - - 0.000000000000000007414 96.0
GDHHQS2_k127_3858572_14 zinc finger - - - 0.00000000000000001024 83.0
GDHHQS2_k127_3858572_2 Belongs to the phosphohexose mutase family K15778 - 5.4.2.2,5.4.2.8 2.198e-224 704.0
GDHHQS2_k127_3858572_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 457.0
GDHHQS2_k127_3858572_4 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 444.0
GDHHQS2_k127_3858572_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 284.0
GDHHQS2_k127_3858572_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000003127 239.0
GDHHQS2_k127_3858572_7 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000000000000000000001098 228.0
GDHHQS2_k127_3858572_8 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000004526 214.0
GDHHQS2_k127_3858572_9 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000156 138.0
GDHHQS2_k127_388815_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 7.283e-295 913.0
GDHHQS2_k127_388815_1 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 353.0
GDHHQS2_k127_388815_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014 - - 0.0000000000000000000000000000000000000000000000062 176.0
GDHHQS2_k127_388815_3 O-methyltransferase - - - 0.0000000000000000000000000000000000000000003264 160.0
GDHHQS2_k127_388815_4 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000007591 163.0
GDHHQS2_k127_388815_6 S25 ribosomal protein K02975 - - 0.0000000000000000000000000000001885 126.0
GDHHQS2_k127_3905105_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 4.541e-293 904.0
GDHHQS2_k127_3905105_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 396.0
GDHHQS2_k127_3905105_10 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000008809 74.0
GDHHQS2_k127_3905105_2 protein conserved in archaea K09723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000198 254.0
GDHHQS2_k127_3905105_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000051 233.0
GDHHQS2_k127_3905105_4 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.000000000000000000000000000000000000000000003612 164.0
GDHHQS2_k127_3905105_7 - - - - 0.00000000000000000000000000000000000000338 146.0
GDHHQS2_k127_3905105_9 - - - - 0.00000000000000000000000002072 111.0
GDHHQS2_k127_3956302_0 Belongs to the MCM family K10726 - - 0.0 1206.0
GDHHQS2_k127_3956302_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0 1088.0
GDHHQS2_k127_3956302_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 603.0
GDHHQS2_k127_3956302_3 Replication factor C K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 503.0
GDHHQS2_k127_3956302_4 GINS complex protein K09723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002333 269.0
GDHHQS2_k127_3956302_5 Belongs to the class-I aminoacyl-tRNA synthetase family - - - 0.000000000000000000000000000000000000000000753 158.0
GDHHQS2_k127_397652_0 DNA polymerase IV (family X) K02347 - - 2.515e-270 841.0
GDHHQS2_k127_397652_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 384.0
GDHHQS2_k127_4021449_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.399e-304 944.0
GDHHQS2_k127_4021449_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 1.891e-235 736.0
GDHHQS2_k127_4021449_10 - - - - 0.0000000000000000000000000000000000000000000000000001537 190.0
GDHHQS2_k127_4021449_11 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000361 178.0
GDHHQS2_k127_4021449_12 Transcriptional regulator K07731 - - 0.000000000000000000000000000000000003863 143.0
GDHHQS2_k127_4021449_13 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02259 - - 0.000000000000000000000000000003446 125.0
GDHHQS2_k127_4021449_14 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000000000000000006286 111.0
GDHHQS2_k127_4021449_2 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 582.0
GDHHQS2_k127_4021449_3 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 374.0
GDHHQS2_k127_4021449_4 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 372.0
GDHHQS2_k127_4021449_5 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 336.0
GDHHQS2_k127_4021449_6 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 288.0
GDHHQS2_k127_4021449_7 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000627 280.0
GDHHQS2_k127_4021449_8 Uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007039 269.0
GDHHQS2_k127_4021449_9 - - - - 0.00000000000000000000000000000000000000000000000000000000391 203.0
GDHHQS2_k127_4029507_0 Radical SAM - - - 0.0 1077.0
GDHHQS2_k127_4029507_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 2.853e-299 931.0
GDHHQS2_k127_4029507_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 1.517e-202 634.0
GDHHQS2_k127_4029507_3 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K17723,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.1,1.3.1.14,1.3.5.2,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 597.0
GDHHQS2_k127_4029507_5 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000004884 149.0
GDHHQS2_k127_4029507_6 Sugar efflux transporter for intercellular exchange K15383 - - 0.00000000000000000000000000006955 119.0
GDHHQS2_k127_4029507_7 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000001505 109.0
GDHHQS2_k127_4042159_0 Predicted membrane protein (DUF2070) K08979 - - 5.671e-206 655.0
GDHHQS2_k127_4042159_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016427,GO:0016428,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 454.0
GDHHQS2_k127_4042159_10 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.000000000000000000000000007283 113.0
GDHHQS2_k127_4042159_11 Circadian clock protein KaiC - - - 0.000000000000000000000004226 109.0
GDHHQS2_k127_4042159_12 response regulator, receiver - - - 0.000000000000000000001561 99.0
GDHHQS2_k127_4042159_13 Sec61beta family - - - 0.00000000000000000001786 91.0
GDHHQS2_k127_4042159_2 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 365.0
GDHHQS2_k127_4042159_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 328.0
GDHHQS2_k127_4042159_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001689 290.0
GDHHQS2_k127_4042159_5 - - - - 0.000000000000000000000000000000000000000000000000000000000001055 216.0
GDHHQS2_k127_4042159_6 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000000000121 203.0
GDHHQS2_k127_4042159_7 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000000001775 192.0
GDHHQS2_k127_4042159_8 Protein involved in ribosomal biogenesis, contains PUA domain K07565 - - 0.00000000000000000000000000000000000000000000000000007509 192.0
GDHHQS2_k127_4069468_0 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 413.0
GDHHQS2_k127_4069468_1 cytochrome-c peroxidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 309.0
GDHHQS2_k127_4069468_2 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000177 251.0
GDHHQS2_k127_4069468_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000001201 147.0
GDHHQS2_k127_4069468_4 - - - - 0.000000000000000000000002577 109.0
GDHHQS2_k127_4089970_0 inner membrane component K02034 - - 9.952e-234 728.0
GDHHQS2_k127_4089970_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001713 225.0
GDHHQS2_k127_4089970_2 Functions by promoting the formation of the first peptide bond K03263 - - 0.00000000000000000000000000000000000000000000000000000000000000002028 226.0
GDHHQS2_k127_4093446_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 466.0
GDHHQS2_k127_4093446_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 346.0
GDHHQS2_k127_4093760_0 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 494.0
GDHHQS2_k127_4093760_1 Galactose oxidase, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 428.0
GDHHQS2_k127_4093760_2 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 400.0
GDHHQS2_k127_4093760_3 PFAM ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 387.0
GDHHQS2_k127_4093760_4 Periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 385.0
GDHHQS2_k127_4093760_5 Ribbon-helix-helix protein, copG family K07722 - - 0.000000000000000000000000000000000000000000000000000853 185.0
GDHHQS2_k127_4093760_6 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000000000000000000007536 176.0
GDHHQS2_k127_4093760_7 RNA-binding protein contains TRAM domain - - - 0.0000000000000000000000000001024 117.0
GDHHQS2_k127_4093760_8 DNA-binding transcription factor activity - - - 0.000000000000000000000005603 103.0
GDHHQS2_k127_4133772_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K01953,K06927 - 6.3.1.14,6.3.5.4 7.917e-232 729.0
GDHHQS2_k127_4133772_1 Mannosyl-3-phosphoglycerate synthase K05947 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 467.0
GDHHQS2_k127_4133772_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 373.0
GDHHQS2_k127_4133772_3 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000209 275.0
GDHHQS2_k127_4133772_4 Domain of unknown function (DUF1297) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000009617 248.0
GDHHQS2_k127_4133772_5 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000003044 233.0
GDHHQS2_k127_4133772_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000001157 231.0
GDHHQS2_k127_4133772_7 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000000000000000000003303 216.0
GDHHQS2_k127_4133772_9 metallopeptidase activity - - - 0.000000000003915 73.0
GDHHQS2_k127_4219187_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 305.0
GDHHQS2_k127_4219187_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000019 145.0
GDHHQS2_k127_4219187_3 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000003887 116.0
GDHHQS2_k127_424008_0 Protein of unknown function, DUF255 K06888 - - 0.0 1129.0
GDHHQS2_k127_424008_1 Pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 334.0
GDHHQS2_k127_424008_11 Domain of unknown function (DUF2024) - - - 0.000000000000172 70.0
GDHHQS2_k127_424008_14 - - - - 0.0009687 42.0
GDHHQS2_k127_424008_2 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000000000000000004194 217.0
GDHHQS2_k127_424008_3 - - - - 0.000000000000000000000000000000000000000001903 159.0
GDHHQS2_k127_424008_5 Transcriptional regulator - - - 0.000000000000000000000000000002858 121.0
GDHHQS2_k127_424008_7 - - - - 0.000000000000000000000001011 104.0
GDHHQS2_k127_4425054_0 Belongs to the UPF0284 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 452.0
GDHHQS2_k127_4425054_1 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 347.0
GDHHQS2_k127_4425054_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 333.0
GDHHQS2_k127_4425054_3 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000002088 252.0
GDHHQS2_k127_4425054_4 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000852 254.0
GDHHQS2_k127_4425054_5 - - - - 0.000000000000000000000000000000000000000000000000002803 183.0
GDHHQS2_k127_4425054_6 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000003174 174.0
GDHHQS2_k127_4425054_9 Transcriptional regulator - - - 0.000000000000000000002762 96.0
GDHHQS2_k127_4491996_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 6.416e-282 871.0
GDHHQS2_k127_4491996_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.319e-273 843.0
GDHHQS2_k127_4491996_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 376.0
GDHHQS2_k127_4491996_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000001067 223.0
GDHHQS2_k127_4491996_4 ATP synthase subunit C K02124 - - 0.000000000000000000000000000426 116.0
GDHHQS2_k127_45604_0 major facilitator superfamily K08153,K08221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 417.0
GDHHQS2_k127_45604_1 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 359.0
GDHHQS2_k127_45604_2 DEAD DEAH box helicase K06877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 314.0
GDHHQS2_k127_45604_3 - - - - 0.000000000000000000000000000000000000000003355 159.0
GDHHQS2_k127_4579613_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 542.0
GDHHQS2_k127_4579613_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 422.0
GDHHQS2_k127_4579613_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000004624 239.0
GDHHQS2_k127_4581669_0 Zn-dependent protease with chaperone function K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 365.0
GDHHQS2_k127_4581669_1 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 243.0
GDHHQS2_k127_4581669_2 - - - - 0.00000000000000000000000000000000000001203 154.0
GDHHQS2_k127_4581669_3 - - - - 0.0000000000000000000000000000000004346 136.0
GDHHQS2_k127_4581669_4 HxlR-like helix-turn-helix - - - 0.0000000000000000000000004903 109.0
GDHHQS2_k127_459644_0 Belongs to the GARS family K01945 - 6.3.4.13 1.932e-212 666.0
GDHHQS2_k127_459644_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 445.0
GDHHQS2_k127_459644_2 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 346.0
GDHHQS2_k127_459644_3 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000004462 169.0
GDHHQS2_k127_459644_4 - - - - 0.000000000000000000000000000000000000009401 151.0
GDHHQS2_k127_459644_5 General stress protein K06884 - - 0.000000000000000749 84.0
GDHHQS2_k127_459941_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 7.396e-296 915.0
GDHHQS2_k127_459941_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 604.0
GDHHQS2_k127_459941_2 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 559.0
GDHHQS2_k127_459941_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 504.0
GDHHQS2_k127_459941_4 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 475.0
GDHHQS2_k127_459941_5 Amino acid kinase family K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 368.0
GDHHQS2_k127_4622462_0 Succinyl-CoA ligase like flavodoxin domain K18593 - - 0.0 1180.0
GDHHQS2_k127_4622462_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 499.0
GDHHQS2_k127_4622462_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 397.0
GDHHQS2_k127_4622462_3 Zinc finger domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 319.0
GDHHQS2_k127_4633529_0 Sodium:solute symporter family - - - 1.194e-243 760.0
GDHHQS2_k127_4633529_1 Belongs to the arginase family K01480 - 3.5.3.11 1.182e-239 741.0
GDHHQS2_k127_4633529_12 Methyltransferase domain - - - 0.00000000009536 72.0
GDHHQS2_k127_4633529_13 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000004574 61.0
GDHHQS2_k127_4633529_2 Deoxyhypusine synthase K00809 - 2.5.1.46 2.228e-206 644.0
GDHHQS2_k127_4633529_3 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 539.0
GDHHQS2_k127_4633529_4 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 468.0
GDHHQS2_k127_4633529_5 TIGRFAM ParB RepB Spo0J family partition protein K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 372.0
GDHHQS2_k127_4633529_6 Translation initiation factor 2, alpha subunit K03237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 355.0
GDHHQS2_k127_4633529_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000000000000003893 230.0
GDHHQS2_k127_4633529_9 - - - - 0.00000000000000000000000000000000000000000001163 166.0
GDHHQS2_k127_4668971_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 1.078e-213 674.0
GDHHQS2_k127_4668971_1 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 291.0
GDHHQS2_k127_4668971_2 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000000000000000000000000000000000000000000001088 229.0
GDHHQS2_k127_4687225_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 1.064e-235 736.0
GDHHQS2_k127_4687225_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 475.0
GDHHQS2_k127_4687225_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 338.0
GDHHQS2_k127_4728277_0 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 355.0
GDHHQS2_k127_4728277_1 - - - - 0.000000000000000000000000000000000000000000000003754 175.0
GDHHQS2_k127_4728277_2 - - - - 0.000000000000000000000000000000000106 142.0
GDHHQS2_k127_4728277_3 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000003378 113.0
GDHHQS2_k127_4728277_4 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000001039 107.0
GDHHQS2_k127_4728277_5 Putative antitoxin - - - 0.0000000000000001035 85.0
GDHHQS2_k127_4745327_0 Peptidase family M1 domain K01256,K13722 - 3.4.11.2 0.0 1219.0
GDHHQS2_k127_4745327_1 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 345.0
GDHHQS2_k127_4745327_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 347.0
GDHHQS2_k127_4745327_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 348.0
GDHHQS2_k127_4745327_4 DNA polymerase IV (family X) K02347 - - 0.0000000000000000000000000000000000000001512 153.0
GDHHQS2_k127_4748273_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 8.485e-270 842.0
GDHHQS2_k127_4748273_1 Belongs to the complex I 49 kDa subunit family K00333 - 1.6.5.3 1.28e-236 733.0
GDHHQS2_k127_4748273_10 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 333.0
GDHHQS2_k127_4748273_11 4Fe-4S binding domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 323.0
GDHHQS2_k127_4748273_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 319.0
GDHHQS2_k127_4748273_13 NADH ubiquinone oxidoreductase 27 kD subunit K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 275.0
GDHHQS2_k127_4748273_14 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005499 244.0
GDHHQS2_k127_4748273_15 AhpC/TSA antioxidant enzyme K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000001242 245.0
GDHHQS2_k127_4748273_16 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000009974 214.0
GDHHQS2_k127_4748273_17 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000002936 207.0
GDHHQS2_k127_4748273_18 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340 - 1.6.5.3 0.000000000000000000000000000000000000000001352 158.0
GDHHQS2_k127_4748273_19 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000000000000000004999 151.0
GDHHQS2_k127_4748273_2 modulator of DNA gyrase K03568 - - 2.379e-225 705.0
GDHHQS2_k127_4748273_20 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00000000002364 71.0
GDHHQS2_k127_4748273_21 Transcriptional regulator - - - 0.00000000148 63.0
GDHHQS2_k127_4748273_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.657e-220 689.0
GDHHQS2_k127_4748273_4 NADH dehydrogenase K00337 - 1.6.5.3 2.134e-213 668.0
GDHHQS2_k127_4748273_5 geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 2.482e-205 644.0
GDHHQS2_k127_4748273_6 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 580.0
GDHHQS2_k127_4748273_7 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 576.0
GDHHQS2_k127_4748273_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 385.0
GDHHQS2_k127_4748273_9 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 331.0
GDHHQS2_k127_4766169_0 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 7.579e-201 629.0
GDHHQS2_k127_4766169_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 507.0
GDHHQS2_k127_4766169_2 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 469.0
GDHHQS2_k127_4766169_3 Lrp/AsnC ligand binding domain K03718 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 279.0
GDHHQS2_k127_4766169_4 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 - 2.1.1.260 0.00000000000000000000000000000000000000000000000000000000004882 213.0
GDHHQS2_k127_4766169_5 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000007081 75.0
GDHHQS2_k127_4772732_0 von Willebrand factor (vWF) type A domain - - - 2.613e-280 872.0
GDHHQS2_k127_4772732_1 ATPase family associated with various cellular activities (AAA) K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 467.0
GDHHQS2_k127_4772732_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000001182 220.0
GDHHQS2_k127_4795281_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 361.0
GDHHQS2_k127_4795281_1 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 354.0
GDHHQS2_k127_4795281_2 RNA methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 323.0
GDHHQS2_k127_4795281_3 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001608 271.0
GDHHQS2_k127_4795281_4 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000000000000002506 129.0
GDHHQS2_k127_4874691_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.733e-293 905.0
GDHHQS2_k127_4874691_1 PFAM TCP-1 cpn60 chaperonin family K22447 - - 1.948e-271 839.0
GDHHQS2_k127_4874691_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 316.0
GDHHQS2_k127_4874691_11 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009981 280.0
GDHHQS2_k127_4874691_12 Chlorophyllase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001606 282.0
GDHHQS2_k127_4874691_13 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002214 255.0
GDHHQS2_k127_4874691_14 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000009754 237.0
GDHHQS2_k127_4874691_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006654 228.0
GDHHQS2_k127_4874691_17 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000002787 195.0
GDHHQS2_k127_4874691_18 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000000000008187 188.0
GDHHQS2_k127_4874691_19 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000113 197.0
GDHHQS2_k127_4874691_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 3.345e-197 617.0
GDHHQS2_k127_4874691_21 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000006263 173.0
GDHHQS2_k127_4874691_22 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000001366 156.0
GDHHQS2_k127_4874691_26 Transcriptional regulator - - - 0.00000000000000000000001102 104.0
GDHHQS2_k127_4874691_27 YHS domain - - - 0.0000000000000000000003027 103.0
GDHHQS2_k127_4874691_29 Pfam:Pyridox_oxidase K07006 - - 0.0000003328 58.0
GDHHQS2_k127_4874691_3 ABC-type transport system, involved in lipoprotein release, permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 4.186e-194 612.0
GDHHQS2_k127_4874691_4 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 550.0
GDHHQS2_k127_4874691_5 LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 481.0
GDHHQS2_k127_4874691_6 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 423.0
GDHHQS2_k127_4874691_7 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 383.0
GDHHQS2_k127_4874691_8 PFAM Ammonia monooxygenase methane monooxygenase, subunit C K10946 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 376.0
GDHHQS2_k127_4874691_9 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 348.0
GDHHQS2_k127_4890013_0 RNA-metabolising metallo-beta-lactamase K07041 - - 7.189e-312 964.0
GDHHQS2_k127_4890013_1 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 1.221e-250 784.0
GDHHQS2_k127_4890013_10 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004629 250.0
GDHHQS2_k127_4890013_12 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000000000000001905 145.0
GDHHQS2_k127_4890013_13 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000119 135.0
GDHHQS2_k127_4890013_14 - - - - 0.0000000000000000000000000000003045 123.0
GDHHQS2_k127_4890013_15 RNA-binding protein contains TRAM domain - - - 0.00000000000000000000001713 108.0
GDHHQS2_k127_4890013_16 Transcriptional regulator - - - 0.000000000000000006937 85.0
GDHHQS2_k127_4890013_17 divalent heavy-metal cations transporter - - - 0.000000000000000562 82.0
GDHHQS2_k127_4890013_18 - - - - 0.00000000000004776 72.0
GDHHQS2_k127_4890013_19 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000002244 76.0
GDHHQS2_k127_4890013_2 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 577.0
GDHHQS2_k127_4890013_20 Pfam:DUF552 K09152 - - 0.00000004816 58.0
GDHHQS2_k127_4890013_3 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 548.0
GDHHQS2_k127_4890013_4 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 519.0
GDHHQS2_k127_4890013_5 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 488.0
GDHHQS2_k127_4890013_6 elongation factor Tu - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 476.0
GDHHQS2_k127_4890013_7 serine-type endopeptidase activity K00505,K01342,K02035 - 1.14.18.1,3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 469.0
GDHHQS2_k127_4890013_8 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 389.0
GDHHQS2_k127_4890013_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 342.0
GDHHQS2_k127_4909430_0 Chorismate mutase type II K00812 - 2.6.1.1 5.068e-205 647.0
GDHHQS2_k127_4909430_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.495e-194 611.0
GDHHQS2_k127_4909430_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 578.0
GDHHQS2_k127_4909430_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000007658 61.0
GDHHQS2_k127_4964007_0 Formyl transferase K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 471.0
GDHHQS2_k127_4964007_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 299.0
GDHHQS2_k127_4964007_2 - - - - 0.0000000000000000000000000000000000000000000000000000002828 199.0
GDHHQS2_k127_4964007_4 snRNP Sm proteins K04796 - - 0.000000000000000000000000000000000000001978 148.0
GDHHQS2_k127_4964007_5 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000008284 160.0
GDHHQS2_k127_4964007_6 Binds to the 23S rRNA K02922 - - 0.00000000000000000000000001484 108.0
GDHHQS2_k127_4964007_7 Transcriptional regulator - - - 0.0000000000003313 73.0
GDHHQS2_k127_5015991_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.4e-256 792.0
GDHHQS2_k127_5015991_1 3-isopropylmalate dehydratase, small subunit K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 315.0
GDHHQS2_k127_5015991_11 ChaB K06197 - - 0.00000000002571 67.0
GDHHQS2_k127_5015991_2 F420-0:Gamma-glutamyl ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 320.0
GDHHQS2_k127_5015991_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008385 262.0
GDHHQS2_k127_5015991_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003054 246.0
GDHHQS2_k127_5015991_5 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000378 251.0
GDHHQS2_k127_5015991_6 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000001245 192.0
GDHHQS2_k127_5015991_7 Winged helix-turn-helix - - - 0.00000000000000000000000000000001705 132.0
GDHHQS2_k127_5015991_8 endonuclease K00986 - 2.7.7.49 0.00000000000000000000000000000002954 128.0
GDHHQS2_k127_5048410_0 ABC1 family - - - 1.737e-256 800.0
GDHHQS2_k127_5048410_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 373.0
GDHHQS2_k127_5048410_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000001638 213.0
GDHHQS2_k127_5048410_3 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000000000004543 175.0
GDHHQS2_k127_5048410_4 protein conserved in archaea - - - 0.00000000000000000000000000000000003481 141.0
GDHHQS2_k127_5048410_5 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000000000000000000000001637 115.0
GDHHQS2_k127_5048410_6 thymidylate kinase K00943 - 2.7.4.9 0.0000008475 53.0
GDHHQS2_k127_5075746_0 magnesium chelatase K03405 - 6.6.1.1 4.077e-304 939.0
GDHHQS2_k127_5075746_1 von Willebrand factor, type A K07114 - - 3.232e-243 758.0
GDHHQS2_k127_5075746_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 287.0
GDHHQS2_k127_5075746_3 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000001187 214.0
GDHHQS2_k127_5076008_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 5.986e-230 715.0
GDHHQS2_k127_5076008_1 Cobalamin B12-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 455.0
GDHHQS2_k127_5076008_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 454.0
GDHHQS2_k127_5076008_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009281 407.0
GDHHQS2_k127_5076008_4 Sugar phosphate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 290.0
GDHHQS2_k127_5076008_5 glucosylceramidase activity - - - 0.0000000000000000000000000000000000000000000005896 170.0
GDHHQS2_k127_5076008_6 with the TIM-barrel fold K07051 - - 0.0000000000000000000000000000000000000788 144.0
GDHHQS2_k127_5076008_7 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000001066 139.0
GDHHQS2_k127_5076008_8 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases K03179 - 2.5.1.39 0.0000000000000000000000000000003627 135.0
GDHHQS2_k127_5076008_9 Dodecin K09165 - - 0.000000005052 59.0
GDHHQS2_k127_5081060_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 2332.0
GDHHQS2_k127_5081060_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 2162.0
GDHHQS2_k127_5081060_10 Participates in transcription termination K02600 - - 0.0000000000000000000000000000000000000000000000000000000003001 206.0
GDHHQS2_k127_5081060_11 Cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000008057 163.0
GDHHQS2_k127_5081060_12 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000000000000000000000000001441 148.0
GDHHQS2_k127_5081060_13 - - - - 0.0000000000000000000000000000000000006795 147.0
GDHHQS2_k127_5081060_14 protein secretion by the type IV secretion system - - - 0.000000000000000000000002069 107.0
GDHHQS2_k127_5081060_15 - K03646 - - 0.0000000000000000000004966 96.0
GDHHQS2_k127_5081060_16 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.0000003906 55.0
GDHHQS2_k127_5081060_2 Carbamoyl-phosphate synthase L chain K18603 - 6.4.1.2,6.4.1.3 4.332e-288 889.0
GDHHQS2_k127_5081060_3 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K18604 - 2.1.3.15,6.4.1.2,6.4.1.3 1.41e-234 735.0
GDHHQS2_k127_5081060_4 - - - - 5.085e-206 644.0
GDHHQS2_k127_5081060_5 ATPase family associated with various cellular activities (AAA) K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 591.0
GDHHQS2_k127_5081060_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 357.0
GDHHQS2_k127_5081060_7 biotin carboxyl carrier K00627,K01571,K15037,K18605 - 2.3.1.12,4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 304.0
GDHHQS2_k127_5081060_8 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008921 273.0
GDHHQS2_k127_5081060_9 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000004359 245.0
GDHHQS2_k127_5082108_0 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 586.0
GDHHQS2_k127_5082108_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 542.0
GDHHQS2_k127_5082108_10 H subunit K02107 - - 0.0000000000000000000000000000000000001224 146.0
GDHHQS2_k127_5082108_11 Activator of Hsp90 ATPase - - - 0.000000000000000000000000005366 115.0
GDHHQS2_k127_5082108_12 - - - - 0.0000000009356 60.0
GDHHQS2_k127_5082108_2 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
GDHHQS2_k127_5082108_4 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 292.0
GDHHQS2_k127_5082108_5 Patch-forming domain C2 of tRNA-guanine transglycosylase K07398 - - 0.00000000000000000000000000000000000000000000000000000000000000000006071 237.0
GDHHQS2_k127_5082108_6 - - - - 0.00000000000000000000000000000000000000000000000000006327 190.0
GDHHQS2_k127_5082108_7 transcription factor, homolog of eukaryotic MBF1 K03627 - - 0.0000000000000000000000000000000000000000000000000009009 186.0
GDHHQS2_k127_5082108_8 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000000000000000000000000000004451 180.0
GDHHQS2_k127_5082108_9 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000002989 164.0
GDHHQS2_k127_519128_0 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 418.0
GDHHQS2_k127_519128_1 Belongs to the MenA family. Type 1 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 305.0
GDHHQS2_k127_519128_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 292.0
GDHHQS2_k127_519128_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004307 254.0
GDHHQS2_k127_519128_4 Methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
GDHHQS2_k127_519128_5 Protein of unknown function (DUF1512) - - - 0.000000000000000000000000000000000000000002075 158.0
GDHHQS2_k127_519128_6 4-hydroxybenzoate synthetase (chorismate lyase) K03181,K06984 - 2.4.2.54,4.1.3.40 0.00000000000000000000000000000000001584 145.0
GDHHQS2_k127_519128_7 - - - - 0.00000000000000000000000000000003042 127.0
GDHHQS2_k127_519128_9 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K21929 - 3.2.2.27 0.0000000000000000000001866 97.0
GDHHQS2_k127_5230242_0 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009562 318.0
GDHHQS2_k127_5230242_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 305.0
GDHHQS2_k127_5230242_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000006718 204.0
GDHHQS2_k127_5230242_3 - - - - 0.000000000000000000000000000000000000000000000001026 178.0
GDHHQS2_k127_5230242_4 - - - - 0.000000000000000000000000000000000000001015 154.0
GDHHQS2_k127_5230242_5 tRNA pseudouridine synthase K06176 - 5.4.99.27 0.00000000000000000000000000008733 115.0
GDHHQS2_k127_5259400_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 623.0
GDHHQS2_k127_5259400_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 462.0
GDHHQS2_k127_5259400_2 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.00000000000000000000000000000000000000000000000000000000000000000009036 232.0
GDHHQS2_k127_5259400_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000002384 201.0
GDHHQS2_k127_5310511_0 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 2.287e-212 663.0
GDHHQS2_k127_5310511_1 Type III restriction enzyme, res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 494.0
GDHHQS2_k127_5310511_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 348.0
GDHHQS2_k127_5310511_3 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000001053 228.0
GDHHQS2_k127_5310511_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000001452 179.0
GDHHQS2_k127_5310511_5 phosphoribosyltransferases K04096,K07100 - - 0.0000000000000000000000000000000000000000000001756 171.0
GDHHQS2_k127_540330_0 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 490.0
GDHHQS2_k127_540330_1 oxidoreductase FAD NAD(P)-binding K00523,K00528 - 1.17.1.1,1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 391.0
GDHHQS2_k127_540330_10 - - - - 0.00000000000000000000000000000000000001039 147.0
GDHHQS2_k127_540330_11 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000000000000000000000003524 142.0
GDHHQS2_k127_540330_12 - - - - 0.00000001078 63.0
GDHHQS2_k127_540330_2 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 324.0
GDHHQS2_k127_540330_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 300.0
GDHHQS2_k127_540330_4 COG2406 Protein distantly related to bacterial ferritins K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 285.0
GDHHQS2_k127_540330_5 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 284.0
GDHHQS2_k127_540330_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001347 226.0
GDHHQS2_k127_540330_7 - - - - 0.00000000000000000000000000000000000000000000000000004465 188.0
GDHHQS2_k127_540330_8 - - - - 0.000000000000000000000000000000000000000000000000007892 184.0
GDHHQS2_k127_540330_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000004608 159.0
GDHHQS2_k127_545929_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 4.182e-258 810.0
GDHHQS2_k127_545929_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 571.0
GDHHQS2_k127_545929_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 328.0
GDHHQS2_k127_545929_3 PFAM Sodium calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000206 287.0
GDHHQS2_k127_545929_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000004847 201.0
GDHHQS2_k127_545929_5 - - - - 0.00000000000000000000000000000007637 131.0
GDHHQS2_k127_545929_8 - - - - 0.00000001928 60.0
GDHHQS2_k127_548556_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 562.0
GDHHQS2_k127_548556_1 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 499.0
GDHHQS2_k127_548556_2 RNA-metabolising metallo-beta-lactamase K07041 - - 0.00000000000000000000000000000000000000000000000000000000000000000101 231.0
GDHHQS2_k127_548556_3 - - - - 0.000000000000000000000000000000000000000000007834 168.0
GDHHQS2_k127_5487950_0 Methionine synthase K00548 - 2.1.1.13 4.472e-263 816.0
GDHHQS2_k127_5487950_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 601.0
GDHHQS2_k127_5487950_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006469 238.0
GDHHQS2_k127_5487950_11 - - - - 0.0000000000000000000000000000000000000000009925 161.0
GDHHQS2_k127_5487950_12 - - - - 0.0000000000000000000000000000000000004048 142.0
GDHHQS2_k127_5487950_13 - - - - 0.000000000000000000000000000000000001661 143.0
GDHHQS2_k127_5487950_14 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000002263 112.0
GDHHQS2_k127_5487950_17 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000633 96.0
GDHHQS2_k127_5487950_18 - - - - 0.0000000000000000192 89.0
GDHHQS2_k127_5487950_19 PFAM blue (type 1) copper domain protein - - - 0.00000000000001259 82.0
GDHHQS2_k127_5487950_2 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 568.0
GDHHQS2_k127_5487950_20 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000001411 58.0
GDHHQS2_k127_5487950_21 - - - - 0.000000004404 60.0
GDHHQS2_k127_5487950_3 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 532.0
GDHHQS2_k127_5487950_4 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 434.0
GDHHQS2_k127_5487950_5 Putative transposase DNA-binding domain K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 416.0
GDHHQS2_k127_5487950_6 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 402.0
GDHHQS2_k127_5487950_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 391.0
GDHHQS2_k127_5487950_8 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 249.0
GDHHQS2_k127_5487950_9 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000001912 240.0
GDHHQS2_k127_5501127_0 Radical SAM K06937 - - 0.0 1137.0
GDHHQS2_k127_5501127_1 3-isopropylmalate dehydratase, large subunit K01703 - 4.2.1.33,4.2.1.35 5.512e-276 853.0
GDHHQS2_k127_5501127_10 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 447.0
GDHHQS2_k127_5501127_11 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 413.0
GDHHQS2_k127_5501127_12 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 394.0
GDHHQS2_k127_5501127_13 Archaeal transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 364.0
GDHHQS2_k127_5501127_14 3-isopropylmalate dehydratase, small subunit K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 346.0
GDHHQS2_k127_5501127_15 Nicotinamide-nucleotide adenylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 299.0
GDHHQS2_k127_5501127_16 PFAM Rieske 2Fe-2S domain K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 290.0
GDHHQS2_k127_5501127_17 PFAM Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008002 271.0
GDHHQS2_k127_5501127_18 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003177 241.0
GDHHQS2_k127_5501127_19 iron dependent repressor - - - 0.00000000000000000000000000000000000000000000000000000002272 198.0
GDHHQS2_k127_5501127_2 oligoendopeptidase F - - - 5.548e-235 735.0
GDHHQS2_k127_5501127_20 - - - - 0.000000000000000000000000000000000000000000000000009 184.0
GDHHQS2_k127_5501127_21 - - - - 0.0000000000000000000000000000000000000000000000001102 182.0
GDHHQS2_k127_5501127_22 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000000000000000000000000001434 178.0
GDHHQS2_k127_5501127_23 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000003631 173.0
GDHHQS2_k127_5501127_24 Trm112p-like protein - - - 0.000000000000000000000000000000000008527 138.0
GDHHQS2_k127_5501127_25 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000003985 79.0
GDHHQS2_k127_5501127_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 2.814e-199 627.0
GDHHQS2_k127_5501127_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.267e-195 614.0
GDHHQS2_k127_5501127_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 534.0
GDHHQS2_k127_5501127_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 515.0
GDHHQS2_k127_5501127_7 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 509.0
GDHHQS2_k127_5501127_8 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 463.0
GDHHQS2_k127_5501127_9 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 457.0
GDHHQS2_k127_5523457_0 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 308.0
GDHHQS2_k127_5523457_1 Major Facilitator Superfamily - - - 0.00000000000000000000000008387 121.0
GDHHQS2_k127_5523599_0 Phosphate uptake regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 481.0
GDHHQS2_k127_5523599_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 452.0
GDHHQS2_k127_5523599_2 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 416.0
GDHHQS2_k127_5523599_3 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 345.0
GDHHQS2_k127_5523599_4 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000001455 220.0
GDHHQS2_k127_5611201_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 1.877e-283 874.0
GDHHQS2_k127_5611201_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 8.714e-200 632.0
GDHHQS2_k127_5611201_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 432.0
GDHHQS2_k127_5611201_3 hydrolase (HAD superfamily) K01091,K01560,K01561,K07025 - 3.1.3.18,3.8.1.2,3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 343.0
GDHHQS2_k127_5611201_4 HIT domain K02503 - - 0.00000000000000000000000000000000000000000000000000000000003575 207.0
GDHHQS2_k127_5611201_5 - - - - 0.0000000000000000000000000000000000031 140.0
GDHHQS2_k127_5647004_0 Mg2 transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 479.0
GDHHQS2_k127_5647004_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001548 284.0
GDHHQS2_k127_5647004_2 - - - - 0.000000000000000000000000000000000000000000000387 168.0
GDHHQS2_k127_5647004_3 PFAM Glycosyl transferase family 2 K07011,K11936 - - 0.0000000004021 71.0
GDHHQS2_k127_5671369_0 Heat shock 70 kDa protein K04043 - - 0.0 1032.0
GDHHQS2_k127_5671369_1 PFAM TCP-1 cpn60 chaperonin family K22447 - - 9.745e-311 957.0
GDHHQS2_k127_5671369_10 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000685 207.0
GDHHQS2_k127_5671369_11 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.000000000000000000000000000000000000000000000001769 181.0
GDHHQS2_k127_5671369_13 Binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000000000006949 168.0
GDHHQS2_k127_5671369_15 - - - - 0.00000000000000000000000000000001135 128.0
GDHHQS2_k127_5671369_16 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.000000000000000000000000000001338 122.0
GDHHQS2_k127_5671369_17 zinc finger - - - 0.0000000000000000000000000013 113.0
GDHHQS2_k127_5671369_18 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000002571 110.0
GDHHQS2_k127_5671369_19 Universal stress protein family - - - 0.000000000000008256 79.0
GDHHQS2_k127_5671369_2 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 582.0
GDHHQS2_k127_5671369_20 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000003169 75.0
GDHHQS2_k127_5671369_3 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 516.0
GDHHQS2_k127_5671369_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 494.0
GDHHQS2_k127_5671369_5 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 449.0
GDHHQS2_k127_5671369_6 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 424.0
GDHHQS2_k127_5671369_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 315.0
GDHHQS2_k127_5671369_8 thioesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001522 234.0
GDHHQS2_k127_5671369_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000009362 227.0
GDHHQS2_k127_5725330_0 Kinase binding protein CGI-121 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005539 279.0
GDHHQS2_k127_5725330_1 TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005584 264.0
GDHHQS2_k127_5725330_2 Sua5 YciO YrdC YwlC family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000001427 252.0
GDHHQS2_k127_5725330_3 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000007439 215.0
GDHHQS2_k127_5725330_4 - - - - 0.00000000000000000000000000000000000000000001542 163.0
GDHHQS2_k127_5725330_5 THUMP domain K06963 - - 0.00000000000000000000000000000000000001139 150.0
GDHHQS2_k127_5725330_6 ribosomal protein K02962 - - 0.00000000000000000000000308 104.0
GDHHQS2_k127_5736323_0 Arsenite-activated ATPase ArsA K01551,K13993 - 3.6.3.16 1.828e-201 633.0
GDHHQS2_k127_5736323_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 565.0
GDHHQS2_k127_5736323_11 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000000000000000000002017 212.0
GDHHQS2_k127_5736323_12 PFAM DNA methylase N-4 N-6 K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000195 219.0
GDHHQS2_k127_5736323_15 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000007008 110.0
GDHHQS2_k127_5736323_17 Ammonium Transporter K03320 - - 0.00000000000000001406 84.0
GDHHQS2_k127_5736323_2 Glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 563.0
GDHHQS2_k127_5736323_3 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 536.0
GDHHQS2_k127_5736323_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 524.0
GDHHQS2_k127_5736323_5 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 520.0
GDHHQS2_k127_5736323_6 PFAM 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 348.0
GDHHQS2_k127_5736323_9 Translation initiation factor K03238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003295 251.0
GDHHQS2_k127_5776334_0 PFAM Radical SAM domain protein - - - 4.591e-212 661.0
GDHHQS2_k127_5776334_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 484.0
GDHHQS2_k127_5776334_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 451.0
GDHHQS2_k127_5776334_3 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000000000000000000000000000000000001238 237.0
GDHHQS2_k127_5776334_4 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000002008 170.0
GDHHQS2_k127_5776334_5 PFAM tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000002829 168.0
GDHHQS2_k127_5776334_6 - - - - 0.00000000000000000000000000003174 118.0
GDHHQS2_k127_5776334_7 response regulator, receiver - - - 0.00000000000002793 78.0
GDHHQS2_k127_579510_0 S-adenosylmethionine synthetase K00789 - 2.5.1.6 2.786e-232 721.0
GDHHQS2_k127_579510_1 glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 557.0
GDHHQS2_k127_579510_10 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000001178 215.0
GDHHQS2_k127_579510_11 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.0000000000000000000000000000000000000000000000000000000000005832 211.0
GDHHQS2_k127_579510_12 Tetrahydromethanopterin S-methyltransferase, subunit A K00577 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000811 211.0
GDHHQS2_k127_579510_13 dUTPase - - - 0.0000000000000000000000000000000000000000000000000000009072 194.0
GDHHQS2_k127_579510_14 snRNP Sm proteins K04796 - - 0.00000000000000000000000000000000000002886 144.0
GDHHQS2_k127_579510_2 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 552.0
GDHHQS2_k127_579510_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 494.0
GDHHQS2_k127_579510_5 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 391.0
GDHHQS2_k127_579510_6 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 329.0
GDHHQS2_k127_579510_7 RecA RadA K04482,K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005686 278.0
GDHHQS2_k127_579510_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005605 269.0
GDHHQS2_k127_579510_9 Archaeal TRASH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002016 246.0
GDHHQS2_k127_5796655_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 590.0
GDHHQS2_k127_5796655_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 483.0
GDHHQS2_k127_5796655_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000009133 235.0
GDHHQS2_k127_5796655_3 PRC-barrel domain protein - - - 0.0000000000000000000000000000000000000001224 155.0
GDHHQS2_k127_5796655_5 metal-dependent protease of the PAD1 JAB1 superfamily K21140 - 3.13.1.6 0.00000000000000000000000000000000002015 139.0
GDHHQS2_k127_5803100_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 441.0
GDHHQS2_k127_5803100_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 373.0
GDHHQS2_k127_5803100_2 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000001333 261.0
GDHHQS2_k127_5803100_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007336 229.0
GDHHQS2_k127_5803100_4 Ser thr protein kinase K07176 - - 0.000000000000000000000000000000000000000000000001555 183.0
GDHHQS2_k127_5803100_5 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.0000000000000000000001017 98.0
GDHHQS2_k127_5831137_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.862e-317 977.0
GDHHQS2_k127_5831137_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.196e-270 835.0
GDHHQS2_k127_5831137_10 resolvase K14060 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 331.0
GDHHQS2_k127_5831137_11 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 309.0
GDHHQS2_k127_5831137_13 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000004081 258.0
GDHHQS2_k127_5831137_14 biotin synthase activity K00833,K01012 - 2.6.1.62,2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000003216 229.0
GDHHQS2_k127_5831137_15 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000000000000000000007163 218.0
GDHHQS2_k127_5831137_16 - - - - 0.0000000000000000000000000000000000000000000000000000001052 196.0
GDHHQS2_k127_5831137_17 - - - - 0.00000000000000000000000000000000000000000000000000000589 195.0
GDHHQS2_k127_5831137_18 - - - - 0.0000000000000000000000000000000000000000000000000001492 188.0
GDHHQS2_k127_5831137_19 - - - - 0.0000000000000000000000000000000000000000000000001244 178.0
GDHHQS2_k127_5831137_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.741e-225 705.0
GDHHQS2_k127_5831137_20 - - - - 0.000000000000000000000000000000000000000003453 155.0
GDHHQS2_k127_5831137_21 - - - - 0.0000000000000000000000000000000000000001325 151.0
GDHHQS2_k127_5831137_22 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000004305 138.0
GDHHQS2_k127_5831137_24 xylanase chitin deacetylase K22278 - 3.5.1.104 0.000000000000000000000000007948 113.0
GDHHQS2_k127_5831137_3 component I K01657 - 4.1.3.27 9.417e-223 697.0
GDHHQS2_k127_5831137_4 8-amino-7-oxononanoate synthase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 571.0
GDHHQS2_k127_5831137_5 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 527.0
GDHHQS2_k127_5831137_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 478.0
GDHHQS2_k127_5831137_7 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 354.0
GDHHQS2_k127_5831137_8 conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 349.0
GDHHQS2_k127_5831137_9 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 342.0
GDHHQS2_k127_5882863_0 Glycosyl transferase family group 2 - - - 4.079e-211 663.0
GDHHQS2_k127_5882863_1 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K01090,K06269 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 379.0
GDHHQS2_k127_5882863_10 Transcriptional regulator - - - 0.00000000008938 66.0
GDHHQS2_k127_5882863_11 - - - - 0.000000002998 70.0
GDHHQS2_k127_5882863_12 - - - - 0.0000001148 63.0
GDHHQS2_k127_5882863_13 Transcriptional regulator - - - 0.0000004147 56.0
GDHHQS2_k127_5882863_2 Glycosyl transferase 4-like domain K21011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000133 295.0
GDHHQS2_k127_5882863_3 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000003207 258.0
GDHHQS2_k127_5882863_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000003798 228.0
GDHHQS2_k127_5882863_5 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000197 216.0
GDHHQS2_k127_5882863_6 LmbE homologs - - - 0.0000000000000000000000000000000000000000000064 171.0
GDHHQS2_k127_5882863_7 ribosomal protein K02912 - - 0.00000000000000000000000000000000000000008781 151.0
GDHHQS2_k127_5882863_8 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000012 131.0
GDHHQS2_k127_59970_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 411.0
GDHHQS2_k127_59970_1 ABC transporter K01990 - - 0.0000000000000000000000000007535 113.0
GDHHQS2_k127_59970_2 - - - - 0.00000008807 61.0
GDHHQS2_k127_59970_3 Belongs to the FPP GGPP synthase family K00795,K13789 GO:0003674,GO:0003824,GO:0004161,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 0.000009591 56.0
GDHHQS2_k127_6026033_0 carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 7.509e-218 683.0
GDHHQS2_k127_6026033_1 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 481.0
GDHHQS2_k127_6026033_2 MGS-like domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 462.0
GDHHQS2_k127_6026033_3 restriction endonuclease K07448 - - 0.00000000000000000000000008615 111.0
GDHHQS2_k127_6120403_0 SMC proteins Flexible Hinge Domain K03529 - - 0.0 1589.0
GDHHQS2_k127_6120403_1 Succinyl-CoA ligase like flavodoxin domain K18594 - - 0.0 1206.0
GDHHQS2_k127_6120403_10 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 307.0
GDHHQS2_k127_6120403_12 Toprim domain - - - 0.000000000000000000000000000000000000000000000000000000000000008612 218.0
GDHHQS2_k127_6120403_13 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000753 220.0
GDHHQS2_k127_6120403_14 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000002669 207.0
GDHHQS2_k127_6120403_15 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000000000000000000000000000000000019 156.0
GDHHQS2_k127_6120403_16 - - - - 0.00000000000000000000000000000000000000123 152.0
GDHHQS2_k127_6120403_17 - - - - 0.00000000000000000000000000000000000001298 146.0
GDHHQS2_k127_6120403_18 PFAM blue (type 1) copper domain protein - - - 0.000000000000002581 81.0
GDHHQS2_k127_6120403_19 Circadian clock protein KaiC - - - 0.000000000000003248 83.0
GDHHQS2_k127_6120403_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 4.418e-267 827.0
GDHHQS2_k127_6120403_20 - - - - 0.000000000000004737 76.0
GDHHQS2_k127_6120403_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.726e-213 665.0
GDHHQS2_k127_6120403_4 DNA primase K02316 - - 6.372e-205 644.0
GDHHQS2_k127_6120403_5 Archaeal Nre, N-terminal - - - 7.631e-200 627.0
GDHHQS2_k127_6120403_6 PFAM tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 411.0
GDHHQS2_k127_6120403_7 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
GDHHQS2_k127_6120403_8 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 336.0
GDHHQS2_k127_6120403_9 glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 329.0
GDHHQS2_k127_6123346_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 5.088e-294 917.0
GDHHQS2_k127_6123346_1 ATP synthase (C/AC39) subunit K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 428.0
GDHHQS2_k127_6123346_2 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 389.0
GDHHQS2_k127_6123346_3 ATP synthase subunit C K02124 - - 0.0000005113 51.0
GDHHQS2_k127_6130832_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 1.109e-209 666.0
GDHHQS2_k127_6130832_1 metal-binding integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 297.0
GDHHQS2_k127_6130832_2 zinc finger - - - 0.00000000000000000001647 91.0
GDHHQS2_k127_6182105_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.359e-298 929.0
GDHHQS2_k127_6182105_1 conserved protein implicated in secretion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001902 258.0
GDHHQS2_k127_6182105_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000001323 211.0
GDHHQS2_k127_6182105_4 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000000000000000000000000000001797 208.0
GDHHQS2_k127_6182105_5 - - - - 0.0000000000000000000000001398 106.0
GDHHQS2_k127_6298768_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 531.0
GDHHQS2_k127_6298768_1 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 294.0
GDHHQS2_k127_6298768_3 regulatory protein, arsR - - - 0.000000000000000000000000000000000000000000008387 167.0
GDHHQS2_k127_6298768_4 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000009789 161.0
GDHHQS2_k127_6298768_5 transcription factor, homolog of eukaryotic MBF1 K03627 - - 0.0000000000001321 70.0
GDHHQS2_k127_6426195_0 DNA polymerase K02319 - 2.7.7.7 3.128e-277 858.0
GDHHQS2_k127_6426195_1 FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 503.0
GDHHQS2_k127_6436402_0 PFAM tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 3.827e-237 739.0
GDHHQS2_k127_6436402_2 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K00363,K15762 - 1.7.1.15 0.000000000000000000000000000000000000000000000000001869 183.0
GDHHQS2_k127_6436402_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000002156 149.0
GDHHQS2_k127_6436402_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000005008 101.0
GDHHQS2_k127_6463884_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 452.0
GDHHQS2_k127_6463884_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 417.0
GDHHQS2_k127_6463884_2 glutamine amidotransferase K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000004465 166.0
GDHHQS2_k127_6463884_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000009019 107.0
GDHHQS2_k127_6540307_0 Initiation factor K03242 - - 8.097e-243 753.0
GDHHQS2_k127_6540307_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000000000000000000000000006316 195.0
GDHHQS2_k127_6540307_2 Nucleotide binding protein, PINc K07158 - - 0.0000000000000000000000000000000000000000000000000008603 186.0
GDHHQS2_k127_6540307_3 - - - - 0.0000000000008409 68.0
GDHHQS2_k127_6553178_0 Heme copper-type cytochrome quinol K02274 - 1.9.3.1 1.047e-255 791.0
GDHHQS2_k127_6553178_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 361.0
GDHHQS2_k127_6553178_2 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 310.0
GDHHQS2_k127_6553178_3 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003096 258.0
GDHHQS2_k127_6553178_4 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000009122 158.0
GDHHQS2_k127_6553178_5 - - - - 0.00000000000000000000003598 102.0
GDHHQS2_k127_6553178_6 - - - - 0.00000000000000000005725 92.0
GDHHQS2_k127_6557793_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1450.0
GDHHQS2_k127_6557793_1 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 281.0
GDHHQS2_k127_6557793_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000031 212.0
GDHHQS2_k127_6557793_3 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000000000001024 200.0
GDHHQS2_k127_6557793_5 - - - - 0.00000003873 55.0
GDHHQS2_k127_6585062_0 Aminotransferase class-V - - - 4.42e-221 689.0
GDHHQS2_k127_6585062_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 608.0
GDHHQS2_k127_6585062_2 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 594.0
GDHHQS2_k127_6585062_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 562.0
GDHHQS2_k127_6585062_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 443.0
GDHHQS2_k127_6585062_5 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 376.0
GDHHQS2_k127_6585062_6 Pfam:DUF137 K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 360.0
GDHHQS2_k127_6585062_7 Iron-sulfur cluster assembly accessory protein K13628 - - 0.000000000000000000000000000000000000000000000000000000000000261 212.0
GDHHQS2_k127_6585062_8 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.0000000000000000000000000002086 115.0
GDHHQS2_k127_6654099_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 589.0
GDHHQS2_k127_6654099_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 538.0
GDHHQS2_k127_6654099_10 Sodium hydrogen exchanger - - - 0.000000000001189 70.0
GDHHQS2_k127_6654099_2 NGG1p interacting factor 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 442.0
GDHHQS2_k127_6654099_3 Mn2 -dependent serine threonine protein kinase K08851 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 291.0
GDHHQS2_k127_6654099_4 GTPase of unknown function C-terminal K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008365 252.0
GDHHQS2_k127_6654099_5 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000002154 250.0
GDHHQS2_k127_6654099_6 CBS domain K03498 - - 0.0000000000000000000000000000000000000000000004697 170.0
GDHHQS2_k127_6654099_7 protein secretion by the type IV secretion system - - - 0.000000000000000000000000000000000000000008982 164.0
GDHHQS2_k127_6654099_8 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000004035 133.0
GDHHQS2_k127_6654099_9 - - - - 0.00000000000000000000806 95.0
GDHHQS2_k127_6731752_0 Isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 605.0
GDHHQS2_k127_6731752_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 420.0
GDHHQS2_k127_6731752_10 Tetrapyrrole (Corrin/Porphyrin) Methylases K05934 - 2.1.1.131 0.000000000000000000000000000000000000001001 148.0
GDHHQS2_k127_6731752_2 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 400.0
GDHHQS2_k127_6731752_3 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 329.0
GDHHQS2_k127_6731752_4 Monooxygenase subunit B protein K10945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 314.0
GDHHQS2_k127_6731752_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 297.0
GDHHQS2_k127_6731752_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001892 234.0
GDHHQS2_k127_6731752_7 Methyltransferase small domain K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000008704 211.0
GDHHQS2_k127_6731752_8 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000000000000000004376 162.0
GDHHQS2_k127_6731752_9 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000000000000000000000000000000000008917 166.0
GDHHQS2_k127_6746347_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 385.0
GDHHQS2_k127_6746347_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002596 265.0
GDHHQS2_k127_6746347_2 - - - - 0.000000000000000000000000000000000000000000000000000003655 192.0
GDHHQS2_k127_6746347_4 - - - - 0.000000000000000001722 90.0
GDHHQS2_k127_6746347_5 Amino acid permease - - - 0.000000000000002162 77.0
GDHHQS2_k127_6849705_0 thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 375.0
GDHHQS2_k127_6849705_1 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 309.0
GDHHQS2_k127_6849705_2 Major Intrinsic Protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 304.0
GDHHQS2_k127_6849705_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000006979 198.0
GDHHQS2_k127_6849705_4 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000002867 168.0
GDHHQS2_k127_6849705_6 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000006986 130.0
GDHHQS2_k127_6935147_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.0 1248.0
GDHHQS2_k127_6935147_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 570.0
GDHHQS2_k127_6935147_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 388.0
GDHHQS2_k127_6935147_3 Peptidyl-tRNA hydrolase PTH2 K04794 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000005313 188.0
GDHHQS2_k127_6935147_4 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000000000000000000000000217 142.0
GDHHQS2_k127_6935147_5 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000000000000000000000000000004881 130.0
GDHHQS2_k127_6935147_6 - - - - 0.000000000000000000000000000002139 121.0
GDHHQS2_k127_6935147_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00001323 47.0
GDHHQS2_k127_6959245_0 PFAM TCP-1 cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 522.0
GDHHQS2_k127_6959245_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 326.0
GDHHQS2_k127_6959245_2 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000003339 190.0
GDHHQS2_k127_6959245_3 UreF K03188 - - 0.0000000000000000000002408 102.0
GDHHQS2_k127_7147733_0 Belongs to the enoyl-CoA hydratase isomerase family K01715,K15019 - 4.2.1.116,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 483.0
GDHHQS2_k127_7147733_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 468.0
GDHHQS2_k127_7147733_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 475.0
GDHHQS2_k127_7147733_3 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 418.0
GDHHQS2_k127_7147733_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 413.0
GDHHQS2_k127_7147733_5 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 378.0
GDHHQS2_k127_7147733_6 Gas vesicle synthesis protein GvpL/GvpF - - - 0.00000000000000000005409 97.0
GDHHQS2_k127_7147733_7 response regulator, receiver - - - 0.0000000004152 66.0
GDHHQS2_k127_7147733_8 Dehydrogenase - - - 0.0000004889 54.0
GDHHQS2_k127_7247755_0 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 493.0
GDHHQS2_k127_7247755_1 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000002091 223.0
GDHHQS2_k127_7247755_5 response regulator, receiver - - - 0.0000000000000002947 85.0
GDHHQS2_k127_7294077_0 Belongs to the MCM family K10726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 392.0
GDHHQS2_k127_7294077_2 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000000000000000000000004366 181.0
GDHHQS2_k127_7294077_3 - - - - 0.0000000000000000000000000000000000000000000000009399 175.0
GDHHQS2_k127_7294077_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000001013 176.0
GDHHQS2_k127_7294077_5 - - - - 0.000000000000000000000000000000000008244 138.0
GDHHQS2_k127_7294077_6 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000000000000001836 134.0
GDHHQS2_k127_81402_0 Pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1176.0
GDHHQS2_k127_81402_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 2.432e-268 829.0
GDHHQS2_k127_81402_10 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002552 128.0
GDHHQS2_k127_81402_11 copper ion binding - - - 0.000000000000000000000000000416 119.0
GDHHQS2_k127_81402_12 cheY-homologous receiver domain - - - 0.0000000001872 66.0
GDHHQS2_k127_81402_13 PKD domain containing protein - - - 0.00001061 54.0
GDHHQS2_k127_81402_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 6.851e-223 695.0
GDHHQS2_k127_81402_3 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 480.0
GDHHQS2_k127_81402_4 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 304.0
GDHHQS2_k127_81402_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 301.0
GDHHQS2_k127_81402_6 resistance protein K14166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000836 252.0
GDHHQS2_k127_81402_7 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00000000000000000000000000000000000000000000000009682 187.0
GDHHQS2_k127_81402_8 - - - - 0.000000000000000000000000000000000000000000000001297 181.0
GDHHQS2_k127_81402_9 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000002441 146.0
GDHHQS2_k127_987616_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1373.0
GDHHQS2_k127_987616_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 604.0
GDHHQS2_k127_987616_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 548.0
GDHHQS2_k127_987616_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 353.0
GDHHQS2_k127_987616_4 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 289.0
GDHHQS2_k127_987616_5 Rieske 2Fe-2S K05710 - - 0.0000000000000000000000000000000000000000000000000002252 185.0
GDHHQS2_k127_987616_6 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000000000000000318 186.0
GDHHQS2_k127_987616_7 Transcriptional regulator - - - 0.00000000000000004201 83.0
GDHHQS2_k127_987616_9 - - - - 0.0000001673 55.0
GDHHQS2_k127_998456_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.517e-305 941.0
GDHHQS2_k127_998456_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.617e-216 676.0
GDHHQS2_k127_998456_10 regulatory protein, arsR - - - 0.00000000000000000000000000002521 121.0
GDHHQS2_k127_998456_2 Involved in regulation of DNA replication K10725 - - 2.652e-203 637.0
GDHHQS2_k127_998456_3 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 420.0
GDHHQS2_k127_998456_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 362.0
GDHHQS2_k127_998456_5 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 351.0
GDHHQS2_k127_998456_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000002003 244.0
GDHHQS2_k127_998456_7 ribosomal protein K02976 - - 0.000000000000000000000000000000000000000000000005394 174.0
GDHHQS2_k127_998456_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000000000000000000000007748 174.0