Overview

ID MAG01460
Name GNS2_bin.23
Sample SMP0038
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Thermoleophilia
Order Solirubrobacterales
Family 70-9
Genus VAYN01
Species
Assembly information
Completeness (%) 85.12
Contamination (%) 2.43
GC content (%) 70.0
N50 (bp) 11,364
Genome size (bp) 1,998,303

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1970

Gene name Description KEGG GOs EC E-value Score Sequence
GNS2_k127_105783_0 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 573.0
GNS2_k127_105783_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 364.0
GNS2_k127_105783_2 Helix-turn-helix domain - - - 0.00000000003732 66.0
GNS2_k127_105783_3 Pfam:HipA_N K07154 - 2.7.11.1 0.00000001312 62.0
GNS2_k127_105783_4 - - - - 0.00003674 54.0
GNS2_k127_1113599_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 546.0
GNS2_k127_1113599_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 506.0
GNS2_k127_1113599_2 PFAM aldo keto reductase K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 366.0
GNS2_k127_1113599_3 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 313.0
GNS2_k127_1113599_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 300.0
GNS2_k127_1113599_5 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000001508 254.0
GNS2_k127_1113599_6 Transposase DDE domain group 1 - - - 0.000000000000000000000001652 109.0
GNS2_k127_1172516_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 547.0
GNS2_k127_1172516_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 407.0
GNS2_k127_1172516_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 358.0
GNS2_k127_1172516_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 292.0
GNS2_k127_1172516_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000007056 184.0
GNS2_k127_1172516_5 50S ribosomal protein L4 K02926 - - 0.0000000000000000000000000000000000000000000000003746 182.0
GNS2_k127_1172516_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000004475 150.0
GNS2_k127_1172516_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000006435 149.0
GNS2_k127_1172516_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000006092 127.0
GNS2_k127_1199296_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 7.681e-248 775.0
GNS2_k127_1199296_1 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 7.42e-196 624.0
GNS2_k127_1199296_10 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000006258 167.0
GNS2_k127_1199296_11 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000173 175.0
GNS2_k127_1199296_12 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000002323 157.0
GNS2_k127_1199296_13 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000006089 135.0
GNS2_k127_1199296_14 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000009094 134.0
GNS2_k127_1199296_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000006127 120.0
GNS2_k127_1199296_16 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000634 108.0
GNS2_k127_1199296_17 Lysin motif - - - 0.00000004236 59.0
GNS2_k127_1199296_2 ABC 3 transport family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 567.0
GNS2_k127_1199296_3 pfkB family carbohydrate kinase K00882 - 2.7.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 353.0
GNS2_k127_1199296_4 ATPases associated with a variety of cellular activities K11710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 308.0
GNS2_k127_1199296_5 ABC 3 transport family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001176 286.0
GNS2_k127_1199296_6 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000002767 268.0
GNS2_k127_1199296_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000001414 239.0
GNS2_k127_1199296_8 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000007167 244.0
GNS2_k127_1199296_9 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000003875 173.0
GNS2_k127_1224455_0 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 411.0
GNS2_k127_1224455_1 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 328.0
GNS2_k127_1224455_10 - - - - 0.0000000000000006749 81.0
GNS2_k127_1224455_11 Secreted repeat of unknown function - - - 0.0000000000000008453 84.0
GNS2_k127_1224455_12 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000001336 62.0
GNS2_k127_1224455_13 PFAM PKD domain containing protein - - - 0.0000000384 66.0
GNS2_k127_1224455_14 Protein of unknown function (DUF1778) - - - 0.0000009537 55.0
GNS2_k127_1224455_15 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.000307 45.0
GNS2_k127_1224455_2 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000007425 164.0
GNS2_k127_1224455_3 CYTH - - - 0.000000000000000000000000000000000000000004986 165.0
GNS2_k127_1224455_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000001003 146.0
GNS2_k127_1224455_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000306 135.0
GNS2_k127_1224455_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.000000000000000000000000000001382 126.0
GNS2_k127_1224455_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000973 105.0
GNS2_k127_1224455_8 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000002621 89.0
GNS2_k127_1224455_9 positive regulation of growth - GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050896,GO:0065007,GO:0070482 - 0.0000000000000001436 82.0
GNS2_k127_1288495_0 FAD linked oxidases, C-terminal domain - - - 9.948e-194 622.0
GNS2_k127_1288495_1 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000001185 218.0
GNS2_k127_1312910_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 556.0
GNS2_k127_1312910_1 amine dehydrogenase activity K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 544.0
GNS2_k127_1312910_2 PFAM Rieske 2Fe-2S K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000787 200.0
GNS2_k127_1312910_3 ECF sigma factor K03088 - - 0.00000000000000000000000000000002383 133.0
GNS2_k127_1312910_5 acetyltransferase - - - 0.000000000000001349 87.0
GNS2_k127_1312910_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000004695 60.0
GNS2_k127_1312910_7 - - - - 0.00000001276 67.0
GNS2_k127_1312910_8 Protein of unknown function (DUF2630) - - - 0.0008002 42.0
GNS2_k127_1369404_0 Major Facilitator Superfamily - - - 5.328e-214 676.0
GNS2_k127_1369404_1 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 1.871e-194 611.0
GNS2_k127_1369404_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 GO:0003674,GO:0003824,GO:0004015,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 546.0
GNS2_k127_1369404_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000001013 254.0
GNS2_k127_1369404_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002016 238.0
GNS2_k127_1369404_5 Metallophosphoesterase, calcineurin superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001739 220.0
GNS2_k127_1369404_7 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000257 195.0
GNS2_k127_1369404_8 Acyltransferase - - - 0.00002481 56.0
GNS2_k127_1395554_0 FAD binding domain K10676 - 1.14.13.20 9.305e-230 730.0
GNS2_k127_1395554_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 524.0
GNS2_k127_1395554_10 PFAM NHL repeat containing protein - - - 0.0000000000000003598 94.0
GNS2_k127_1395554_11 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000001216 64.0
GNS2_k127_1395554_12 - - - - 0.0000000006407 67.0
GNS2_k127_1395554_13 Short repeat of unknown function (DUF308) - - - 0.000002621 57.0
GNS2_k127_1395554_14 - - - - 0.00003569 49.0
GNS2_k127_1395554_2 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 303.0
GNS2_k127_1395554_3 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000005715 223.0
GNS2_k127_1395554_4 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001839 222.0
GNS2_k127_1395554_5 gluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000004 206.0
GNS2_k127_1395554_6 Diacylglycerol kinase K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000006325 164.0
GNS2_k127_1395554_7 TetR Family - - - 0.00000000000000000000000000000003458 134.0
GNS2_k127_1395554_8 SEC-C motif - - - 0.00000000000000000000000000002156 128.0
GNS2_k127_1395554_9 - - - - 0.000000000000000000007252 97.0
GNS2_k127_1397311_0 Type III restriction enzyme, res subunit - - - 0.0 1086.0
GNS2_k127_1397311_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.525e-236 737.0
GNS2_k127_1397311_10 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000000007475 200.0
GNS2_k127_1397311_11 - - - - 0.0000000000000000000000000000000000000000000000001079 184.0
GNS2_k127_1397311_12 cell redox homeostasis K02199 - - 0.00000000000000000000000000000000000000000000006556 176.0
GNS2_k127_1397311_13 Domain of unknown function (DUF1906) - - - 0.00000000000000000000000000000000000007917 149.0
GNS2_k127_1397311_14 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000007191 111.0
GNS2_k127_1397311_15 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000568 77.0
GNS2_k127_1397311_17 - - - - 0.00000003718 59.0
GNS2_k127_1397311_2 Uroporphyrinogen-III synthase HemD K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 549.0
GNS2_k127_1397311_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 467.0
GNS2_k127_1397311_4 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 449.0
GNS2_k127_1397311_5 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 344.0
GNS2_k127_1397311_6 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 359.0
GNS2_k127_1397311_7 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 327.0
GNS2_k127_1397311_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000009617 224.0
GNS2_k127_1397311_9 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000003246 222.0
GNS2_k127_1478454_0 1-deoxy-D-xylulose-5-phosphate synthase K01662 - 2.2.1.7 4.606e-298 929.0
GNS2_k127_1478454_1 Bacterial low temperature requirement A protein (LtrA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 462.0
GNS2_k127_1478454_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000002808 158.0
GNS2_k127_1478454_11 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000009128 126.0
GNS2_k127_1478454_12 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000003556 120.0
GNS2_k127_1478454_2 peptidase M42 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 401.0
GNS2_k127_1478454_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 385.0
GNS2_k127_1478454_4 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 359.0
GNS2_k127_1478454_5 Short-chain alcohol dehydrogenase K16066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 316.0
GNS2_k127_1478454_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 311.0
GNS2_k127_1478454_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008768 261.0
GNS2_k127_1478454_8 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006559 244.0
GNS2_k127_1478454_9 COG3663 G T U mismatch-specific DNA glycosylase K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000006479 175.0
GNS2_k127_153702_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 515.0
GNS2_k127_153702_1 Belongs to the CinA family K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 489.0
GNS2_k127_153702_2 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 391.0
GNS2_k127_153702_3 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000002426 174.0
GNS2_k127_153702_4 Helix-turn-helix domain - - - 0.00000000000000000000000000000448 129.0
GNS2_k127_153702_5 LigT like Phosphoesterase K01975 - 3.1.4.58 0.0000000000000000000003805 104.0
GNS2_k127_153702_6 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000001243 78.0
GNS2_k127_1662201_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000005437 238.0
GNS2_k127_1662201_1 Beta-galactosidase - - - 0.00000000000000000000000000000000000002086 159.0
GNS2_k127_1662201_2 Helix-turn-helix domain - - - 0.00000001106 59.0
GNS2_k127_1662201_3 family transcriptional regulator - - - 0.0000001021 57.0
GNS2_k127_1698337_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.113e-244 782.0
GNS2_k127_1698337_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 495.0
GNS2_k127_1698337_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 389.0
GNS2_k127_1698337_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001064 293.0
GNS2_k127_1698337_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007039 269.0
GNS2_k127_1698337_5 tRNA rRNA methyltransferase, SpoU K03437 - - 0.00000000000000000000000000000000000000000000000000000026 203.0
GNS2_k127_1698337_6 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000002137 149.0
GNS2_k127_1698337_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000003744 141.0
GNS2_k127_1698337_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000003924 98.0
GNS2_k127_1761909_0 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 379.0
GNS2_k127_1761909_1 KR domain K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 327.0
GNS2_k127_1761909_10 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000004209 150.0
GNS2_k127_1761909_11 light absorption K06893 - - 0.00000000000000000000000000000000000004963 147.0
GNS2_k127_1761909_12 Sap, sulfolipid-1-addressing protein - - - 0.00000000000000000000002855 108.0
GNS2_k127_1761909_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001378 271.0
GNS2_k127_1761909_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000009521 247.0
GNS2_k127_1761909_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000003844 242.0
GNS2_k127_1761909_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000006672 244.0
GNS2_k127_1761909_6 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000001189 221.0
GNS2_k127_1761909_7 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000006239 201.0
GNS2_k127_1761909_8 coenzyme F420 binding - - - 0.0000000000000000000000000000000000000000000000001485 191.0
GNS2_k127_1761909_9 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000005032 179.0
GNS2_k127_1809571_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 337.0
GNS2_k127_1809571_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000005552 193.0
GNS2_k127_1809571_2 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000002096 154.0
GNS2_k127_1809571_3 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000002284 134.0
GNS2_k127_1809571_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000003113 111.0
GNS2_k127_1809571_5 Common central domain of tyrosinase K00505 - 1.14.18.1 0.00000000003458 67.0
GNS2_k127_1860361_0 Penicillin amidase - - - 1.751e-229 743.0
GNS2_k127_1860361_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.075e-206 657.0
GNS2_k127_1860361_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000004442 146.0
GNS2_k127_1860361_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000006894 139.0
GNS2_k127_1860361_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000001604 129.0
GNS2_k127_1860361_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000001971 130.0
GNS2_k127_1860361_14 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000002621 105.0
GNS2_k127_1860361_15 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000002869 72.0
GNS2_k127_1860361_16 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000006944 61.0
GNS2_k127_1860361_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 403.0
GNS2_k127_1860361_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 289.0
GNS2_k127_1860361_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004544 267.0
GNS2_k127_1860361_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006224 277.0
GNS2_k127_1860361_6 Belongs to the universal ribosomal protein uS5 family K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007247 260.0
GNS2_k127_1860361_7 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000008603 221.0
GNS2_k127_1860361_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000004505 210.0
GNS2_k127_1860361_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000001096 179.0
GNS2_k127_1922669_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 539.0
GNS2_k127_1922669_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 438.0
GNS2_k127_1922669_10 - - - - 0.00000000000001752 76.0
GNS2_k127_1922669_11 PFAM thioesterase superfamily - - - 0.000000000006365 77.0
GNS2_k127_1922669_12 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000503 70.0
GNS2_k127_1922669_2 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 436.0
GNS2_k127_1922669_3 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002599 266.0
GNS2_k127_1922669_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006448 263.0
GNS2_k127_1922669_5 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000009574 239.0
GNS2_k127_1922669_6 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000002553 195.0
GNS2_k127_1922669_7 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000004237 140.0
GNS2_k127_1922669_8 FAD linked K00803 - 2.5.1.26 0.0000000000000000000000000005665 113.0
GNS2_k127_1922669_9 Putative zinc-finger - - - 0.00000000000000000001206 101.0
GNS2_k127_2037122_0 Helix-hairpin-helix motif K14162 - 2.7.7.7 0.0 1233.0
GNS2_k127_2037122_1 impB/mucB/samB family - - - 0.00000000000000000000000000000000000000000000000000000007547 208.0
GNS2_k127_2037122_2 PFAM Common central domain of tyrosinase K00505,K02674 - 1.14.18.1 0.00000000000000000000000000000000000000000000000009986 191.0
GNS2_k127_2037122_3 - - - - 0.000000000000000001075 87.0
GNS2_k127_2037122_4 - K00505 - 1.14.18.1 0.000000000000001369 90.0
GNS2_k127_2037122_5 Bacterial regulatory proteins, tetR family - - - 0.000392 44.0
GNS2_k127_2091845_0 MMPL family - - - 2.07e-221 711.0
GNS2_k127_2091845_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 514.0
GNS2_k127_2091845_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000006688 207.0
GNS2_k127_2091845_11 F420H(2)-dependent quinone reductase - GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363 - 0.0000000000000000000000000000002584 128.0
GNS2_k127_2091845_12 Electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000003333 126.0
GNS2_k127_2091845_13 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000001589 121.0
GNS2_k127_2091845_14 cell redox homeostasis K02199,K03671 - - 0.0000000000000000000000001391 120.0
GNS2_k127_2091845_15 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000006654 115.0
GNS2_k127_2091845_16 SnoaL-like domain - - - 0.000000000000000000002763 97.0
GNS2_k127_2091845_17 Cupredoxin-like domain - - - 0.00000000000000004499 86.0
GNS2_k127_2091845_18 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0000000008744 72.0
GNS2_k127_2091845_19 cell adhesion involved in biofilm formation K01186,K20276 - 3.2.1.18 0.000000002803 70.0
GNS2_k127_2091845_2 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 423.0
GNS2_k127_2091845_20 OmpA family K03286 - - 0.0005241 53.0
GNS2_k127_2091845_3 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 346.0
GNS2_k127_2091845_4 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
GNS2_k127_2091845_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 311.0
GNS2_k127_2091845_6 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002373 272.0
GNS2_k127_2091845_7 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000008325 238.0
GNS2_k127_2091845_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000005964 213.0
GNS2_k127_2091845_9 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000006122 200.0
GNS2_k127_2114782_0 Alanine-glyoxylate amino-transferase K05825 - - 4.275e-197 630.0
GNS2_k127_2114782_1 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 477.0
GNS2_k127_2114782_10 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004869 282.0
GNS2_k127_2114782_11 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001966 274.0
GNS2_k127_2114782_12 - - - - 0.000000000000000000000001346 114.0
GNS2_k127_2114782_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 455.0
GNS2_k127_2114782_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 453.0
GNS2_k127_2114782_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 380.0
GNS2_k127_2114782_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 370.0
GNS2_k127_2114782_6 AsnC-type helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 320.0
GNS2_k127_2114782_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 316.0
GNS2_k127_2114782_8 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 310.0
GNS2_k127_2114782_9 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 287.0
GNS2_k127_2158965_0 Belongs to the SEDS family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 569.0
GNS2_k127_2158965_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 471.0
GNS2_k127_2158965_10 Protein of unknown function (DUF2662) - - - 0.0000000000000000000000000000006084 124.0
GNS2_k127_2158965_11 Forkhead associated domain - - - 0.0000000000000000000000000002308 119.0
GNS2_k127_2158965_2 Penicillin binding protein transpeptidase domain K05364 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 423.0
GNS2_k127_2158965_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 338.0
GNS2_k127_2158965_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 338.0
GNS2_k127_2158965_5 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000108 273.0
GNS2_k127_2158965_6 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007042 265.0
GNS2_k127_2158965_7 Protein of unknown function (DUF2662) - - - 0.00000000000000000000000000000000000005538 147.0
GNS2_k127_2158965_8 HNH nucleases - - - 0.0000000000000000000000000000000000003779 155.0
GNS2_k127_2158965_9 - - - - 0.0000000000000000000000000000001483 138.0
GNS2_k127_2169574_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 466.0
GNS2_k127_2169574_1 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 344.0
GNS2_k127_2169574_2 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000001703 131.0
GNS2_k127_2169574_3 protein disulfide oxidoreductase activity - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000002745 130.0
GNS2_k127_2218815_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1287.0
GNS2_k127_2218815_1 FAD linked oxidases, C-terminal domain - - - 1.332e-196 627.0
GNS2_k127_2218815_10 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000008106 114.0
GNS2_k127_2218815_11 DDE domain - - - 0.0000000000000000000001121 98.0
GNS2_k127_2218815_12 Domain of unknown function (DUF4160) - - - 0.000000000000000000002627 95.0
GNS2_k127_2218815_13 Protein of unknown function (DUF2442) - - - 0.000000000000003582 79.0
GNS2_k127_2218815_15 isomerase activity K01821 - 5.3.2.6 0.0000001793 59.0
GNS2_k127_2218815_16 alpha/beta hydrolase fold - - - 0.0000003429 64.0
GNS2_k127_2218815_17 - - - - 0.0000009202 58.0
GNS2_k127_2218815_18 mRNA binding K07339 - - 0.0000478 49.0
GNS2_k127_2218815_2 DNA polymerase X K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 588.0
GNS2_k127_2218815_3 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 554.0
GNS2_k127_2218815_4 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 290.0
GNS2_k127_2218815_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001719 268.0
GNS2_k127_2218815_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000001857 211.0
GNS2_k127_2218815_7 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000002153 181.0
GNS2_k127_2218815_8 - - - - 0.00000000000000000000000000000000000007116 147.0
GNS2_k127_2218815_9 response to heat K07090 - - 0.00000000000000000000000000000001365 130.0
GNS2_k127_2284809_0 Oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 322.0
GNS2_k127_2284809_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003734 281.0
GNS2_k127_2284809_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000553 110.0
GNS2_k127_2336944_0 Major Facilitator Superfamily - - - 2.345e-217 685.0
GNS2_k127_2336944_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000004492 160.0
GNS2_k127_2336944_2 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000001057 144.0
GNS2_k127_2336944_3 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000003922 127.0
GNS2_k127_2372192_0 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 566.0
GNS2_k127_2372192_1 D-arabinono-1,4-lactone oxidase K00103 - 1.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 476.0
GNS2_k127_2372192_2 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 312.0
GNS2_k127_2372192_3 Alanine racemase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 297.0
GNS2_k127_2372192_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 293.0
GNS2_k127_2372192_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001426 285.0
GNS2_k127_2372192_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000002609 105.0
GNS2_k127_2372192_7 Ion channel - - - 0.00000000000000000000001189 112.0
GNS2_k127_2372192_8 - - - - 0.0000000000000001115 84.0
GNS2_k127_2441317_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 310.0
GNS2_k127_2441317_1 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 301.0
GNS2_k127_2441317_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005475 294.0
GNS2_k127_2441317_3 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001702 289.0
GNS2_k127_2441317_4 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003365 246.0
GNS2_k127_2441317_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000001654 246.0
GNS2_k127_2441317_6 chlorophyll binding - - - 0.00000000000000000000000003584 117.0
GNS2_k127_2441317_7 Glycosyl transferase 4-like - - - 0.000000000000005234 81.0
GNS2_k127_2441317_9 - K03561,K12287 - - 0.0000000002049 77.0
GNS2_k127_2528560_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 363.0
GNS2_k127_2528560_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 340.0
GNS2_k127_2528560_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 325.0
GNS2_k127_2528560_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005745 251.0
GNS2_k127_2528560_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000002117 263.0
GNS2_k127_2528560_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000002767 230.0
GNS2_k127_2528560_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000005328 211.0
GNS2_k127_2528560_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000001782 151.0
GNS2_k127_2528560_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000004721 120.0
GNS2_k127_2528560_9 YGGT family K02221 - - 0.00000000000000007525 85.0
GNS2_k127_2545926_0 Clp protease K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 314.0
GNS2_k127_2545926_1 COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription - - - 0.00000000000000000000000000000000000000000000000000000000000000002601 234.0
GNS2_k127_2545926_2 Glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000967 210.0
GNS2_k127_2545926_4 Histidine kinase K07652 - 2.7.13.3 0.0000000000000000000000000000000000000000000003271 183.0
GNS2_k127_2545926_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000001053 93.0
GNS2_k127_2545926_6 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00003863 55.0
GNS2_k127_256680_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 462.0
GNS2_k127_256680_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002157 271.0
GNS2_k127_256680_2 ORF6N domain - - - 0.0000000000000000000000000000000000000000000000126 179.0
GNS2_k127_256680_3 OsmC-like protein K07397 - - 0.000000000000000000000000000000004387 133.0
GNS2_k127_256869_0 ATPase family associated with various cellular activities (AAA) K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 426.0
GNS2_k127_256869_1 Peptidase family S51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
GNS2_k127_256869_2 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002015 270.0
GNS2_k127_256869_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002723 246.0
GNS2_k127_256869_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000008423 216.0
GNS2_k127_256869_5 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000007364 206.0
GNS2_k127_256869_6 Iron-storage protein K22336 GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000001276 194.0
GNS2_k127_256869_7 Peptidase family S51 - - - 0.00000000000000000000000000000000000000000000000000004548 208.0
GNS2_k127_256869_8 DNA-templated transcription, initiation K02405,K03088 - - 0.000000000000000000000001591 109.0
GNS2_k127_256869_9 Belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 0.0000000000000004969 83.0
GNS2_k127_2645471_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 488.0
GNS2_k127_2645471_1 Peptidoglycan-binding domain 1 protein K01233 - 3.2.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 361.0
GNS2_k127_2645471_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001876 261.0
GNS2_k127_2645471_3 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004674 249.0
GNS2_k127_2645471_4 Fumarylacetoacetate (FAA) hydrolase family K16164 - 3.7.1.5 0.0000000000000000000000000000000000000000005382 160.0
GNS2_k127_2645471_5 synthase K00574 - 2.1.1.79 0.0000000001402 74.0
GNS2_k127_2745685_0 K+ potassium transporter - - - 9.34e-272 850.0
GNS2_k127_2745685_1 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 291.0
GNS2_k127_2745685_2 Chaperonin 10 Kd subunit - - - 0.000000000000000000000000000000000000000000008762 167.0
GNS2_k127_2745685_3 nuclease activity K06218 - - 0.00000000000000000000000000008876 117.0
GNS2_k127_2745685_4 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.000000000000000000000000002414 120.0
GNS2_k127_2745685_5 - - - - 0.00000000000000000000008058 106.0
GNS2_k127_2745685_6 Nucleotidyltransferase domain K07075 - - 0.00000009906 58.0
GNS2_k127_28919_0 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 559.0
GNS2_k127_28919_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 443.0
GNS2_k127_28919_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 430.0
GNS2_k127_28919_3 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 418.0
GNS2_k127_28919_4 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 385.0
GNS2_k127_28919_5 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 349.0
GNS2_k127_28919_6 Protein export membrane protein - - - 0.000000000000000000000000000000000000000153 160.0
GNS2_k127_2950349_0 WYL domain K13573 - - 2.027e-265 834.0
GNS2_k127_2950349_1 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 545.0
GNS2_k127_2950349_2 filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 300.0
GNS2_k127_2950349_3 ThiJ PfpI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002527 262.0
GNS2_k127_2950349_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009517 254.0
GNS2_k127_2950349_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000542 215.0
GNS2_k127_2958475_0 alpha beta alpha domain I K01840 - 5.4.2.8 1.771e-195 625.0
GNS2_k127_2958475_1 D-Lysine 56-aminomutase, alpha subunit K01844 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 609.0
GNS2_k127_2958475_10 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 349.0
GNS2_k127_2958475_11 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 313.0
GNS2_k127_2958475_12 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 312.0
GNS2_k127_2958475_13 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001676 297.0
GNS2_k127_2958475_14 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001709 302.0
GNS2_k127_2958475_15 cobalamin binding K18011 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009797 279.0
GNS2_k127_2958475_16 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000009638 255.0
GNS2_k127_2958475_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001343 239.0
GNS2_k127_2958475_18 40-residue YVTN family beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000007684 229.0
GNS2_k127_2958475_19 Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000002615 203.0
GNS2_k127_2958475_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 596.0
GNS2_k127_2958475_20 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000453 201.0
GNS2_k127_2958475_21 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000001592 182.0
GNS2_k127_2958475_22 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000002371 183.0
GNS2_k127_2958475_23 ribonuclease activity - - - 0.0000000000000000000000000000000000000000003564 162.0
GNS2_k127_2958475_24 ThiS family K03636 - - 0.00000000000000000000000000000001377 128.0
GNS2_k127_2958475_25 PIN domain - - - 0.0000000000000000000000000001685 120.0
GNS2_k127_2958475_26 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000002349 115.0
GNS2_k127_2958475_27 response regulator - - - 0.00000000000000000006211 99.0
GNS2_k127_2958475_28 SpoVT / AbrB like domain - - - 0.000000000000742 72.0
GNS2_k127_2958475_29 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000007626 74.0
GNS2_k127_2958475_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 525.0
GNS2_k127_2958475_30 Phage integrase family - - - 0.000000784 53.0
GNS2_k127_2958475_31 heme-binding sites - - - 0.000003112 60.0
GNS2_k127_2958475_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 454.0
GNS2_k127_2958475_5 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 439.0
GNS2_k127_2958475_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 418.0
GNS2_k127_2958475_7 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 411.0
GNS2_k127_2958475_8 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 373.0
GNS2_k127_2958475_9 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 349.0
GNS2_k127_2997777_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1210.0
GNS2_k127_2997777_1 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 2.224e-256 806.0
GNS2_k127_2997777_10 zinc-ribbons - - - 0.000000000000000000000001714 104.0
GNS2_k127_2997777_11 - - - - 0.00001303 57.0
GNS2_k127_2997777_12 - - - - 0.0002712 52.0
GNS2_k127_2997777_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 2.747e-242 797.0
GNS2_k127_2997777_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.397e-209 674.0
GNS2_k127_2997777_4 Ribulose-phosphate 3-epimerase K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 287.0
GNS2_k127_2997777_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004359 294.0
GNS2_k127_2997777_6 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001547 293.0
GNS2_k127_2997777_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000009884 204.0
GNS2_k127_2997777_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000001711 201.0
GNS2_k127_2997777_9 Bacterial PH domain - - - 0.00000000000000000000000000000000009786 145.0
GNS2_k127_3038611_0 DNA polymerase K02335 - 2.7.7.7 3.419e-308 972.0
GNS2_k127_3038611_1 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 520.0
GNS2_k127_3038611_2 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000004041 196.0
GNS2_k127_3038611_3 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000000000002929 158.0
GNS2_k127_3038611_4 Sigma-70, region 4 - - - 0.00000000000000000000000000000377 136.0
GNS2_k127_3038611_5 domain, Protein - - - 0.00000000305 68.0
GNS2_k127_3038611_6 Putative inner membrane exporter, YdcZ K09936 - - 0.0000006803 55.0
GNS2_k127_3047280_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 510.0
GNS2_k127_3047280_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 477.0
GNS2_k127_3047280_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000003537 193.0
GNS2_k127_3047280_11 response to pH - - - 0.0000000000000000000000000000000000001766 151.0
GNS2_k127_3047280_12 HNH endonuclease - - - 0.0000001196 57.0
GNS2_k127_3047280_14 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0004335 47.0
GNS2_k127_3047280_2 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 452.0
GNS2_k127_3047280_3 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 416.0
GNS2_k127_3047280_4 PucR C-terminal helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 401.0
GNS2_k127_3047280_5 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 297.0
GNS2_k127_3047280_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000002926 228.0
GNS2_k127_3047280_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000002698 223.0
GNS2_k127_3047280_8 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000001094 203.0
GNS2_k127_3047280_9 - - - - 0.00000000000000000000000000000000000000000000000001017 191.0
GNS2_k127_3071454_0 AAA ATPase domain - - - 8.016e-202 667.0
GNS2_k127_3071454_1 FAD linked oxidase domain protein K16653 - 1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 354.0
GNS2_k127_3071454_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 300.0
GNS2_k127_3071454_3 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001248 276.0
GNS2_k127_3071454_4 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000000000003917 125.0
GNS2_k127_3071454_5 Beta-galactosidase - - - 0.000000000000000000000001055 113.0
GNS2_k127_3071454_6 Protein of unknown function DUF86 - - - 0.00000525 50.0
GNS2_k127_3080383_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 609.0
GNS2_k127_3131503_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 2.208e-236 736.0
GNS2_k127_3131503_1 cell envelope-related transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001613 247.0
GNS2_k127_3131503_2 Regulatory protein, FmdB - - - 0.00000000000000000000006992 103.0
GNS2_k127_3143438_0 Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.311e-210 673.0
GNS2_k127_3143438_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 4.644e-206 670.0
GNS2_k127_3143438_10 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000000000000002527 133.0
GNS2_k127_3143438_11 Transposase - - - 0.00000000000000000000000000000005808 130.0
GNS2_k127_3143438_12 - - - - 0.00000000000001723 79.0
GNS2_k127_3143438_2 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 527.0
GNS2_k127_3143438_3 Domain of unknown function (DUF1802) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 354.0
GNS2_k127_3143438_4 Glucose inhibited division protein A K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 295.0
GNS2_k127_3143438_5 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003059 268.0
GNS2_k127_3143438_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000001322 239.0
GNS2_k127_3143438_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000008406 236.0
GNS2_k127_3143438_9 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000000000000000000000000000000000000000000000003591 209.0
GNS2_k127_3146167_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1094.0
GNS2_k127_3146167_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 418.0
GNS2_k127_3146167_10 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000001762 89.0
GNS2_k127_3146167_11 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000179 76.0
GNS2_k127_3146167_12 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000131 71.0
GNS2_k127_3146167_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 405.0
GNS2_k127_3146167_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002729 259.0
GNS2_k127_3146167_4 60Kd inner membrane protein K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006664 256.0
GNS2_k127_3146167_5 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000004059 192.0
GNS2_k127_3146167_6 single-stranded nucleic acid binding R3H K06346 - - 0.000000000000000000000000000000000006603 142.0
GNS2_k127_3146167_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000006624 136.0
GNS2_k127_3146167_8 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000002584 123.0
GNS2_k127_3146167_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001343 119.0
GNS2_k127_3162928_0 Clp domain protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1093.0
GNS2_k127_3162928_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 592.0
GNS2_k127_3162928_10 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000002998 198.0
GNS2_k127_3162928_11 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000007517 175.0
GNS2_k127_3162928_12 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000002258 150.0
GNS2_k127_3162928_13 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.00000005952 59.0
GNS2_k127_3162928_14 Histidine kinase - - - 0.0000005725 60.0
GNS2_k127_3162928_2 DNA integrity scanning protein DisA K07067 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 556.0
GNS2_k127_3162928_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 555.0
GNS2_k127_3162928_4 Dihydrouridine synthase (Dus) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 391.0
GNS2_k127_3162928_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 307.0
GNS2_k127_3162928_6 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003642 259.0
GNS2_k127_3162928_7 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000003187 252.0
GNS2_k127_3162928_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000002015 224.0
GNS2_k127_3162928_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000001067 203.0
GNS2_k127_3168588_0 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00381 - 1.7.7.1,1.8.1.2 1.412e-294 914.0
GNS2_k127_3168588_1 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 1.416e-229 719.0
GNS2_k127_3168588_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 535.0
GNS2_k127_3168588_3 PUA-like domain K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 420.0
GNS2_k127_3168588_4 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000126 272.0
GNS2_k127_3168588_5 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000007679 228.0
GNS2_k127_3168588_6 Purine catabolism regulatory protein-like family K09684 - - 0.000000000000000000000000000000000000000000000000000002958 194.0
GNS2_k127_3168588_7 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000001932 151.0
GNS2_k127_3168588_8 Rhodanese Homology Domain - - - 0.000000000000000000001975 100.0
GNS2_k127_3168588_9 Dodecin K09165 - - 0.000002458 54.0
GNS2_k127_3277288_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 509.0
GNS2_k127_3277288_1 Starch synthase catalytic domain K16150 - 2.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 448.0
GNS2_k127_3277288_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 421.0
GNS2_k127_3277288_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 364.0
GNS2_k127_3277288_4 Tubulin/FtsZ family, GTPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 351.0
GNS2_k127_3277288_5 Domain of unknown function (DUF1957) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 338.0
GNS2_k127_3277288_6 Adenylate cyclase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001208 281.0
GNS2_k127_3277288_7 HipA N-terminal domain K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000005483 257.0
GNS2_k127_3277288_8 sequence-specific DNA binding K15773 - - 0.0002801 46.0
GNS2_k127_3279333_0 B12 binding domain K00548 - 2.1.1.13 0.0 1179.0
GNS2_k127_3279333_1 Glycosyl transferases group 1 K08256 - 2.4.1.345 1.108e-235 751.0
GNS2_k127_3279333_2 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004434 249.0
GNS2_k127_3279333_3 - - - - 0.0000002124 61.0
GNS2_k127_3300394_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 504.0
GNS2_k127_3300394_1 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 506.0
GNS2_k127_3300394_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 398.0
GNS2_k127_3300394_3 RecF/RecN/SMC N terminal domain K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 356.0
GNS2_k127_3346879_0 Sulfatase - - - 2.076e-233 744.0
GNS2_k127_3346879_1 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 1.351e-221 709.0
GNS2_k127_3346879_10 FG-GAP repeat protein - - - 0.0000002029 61.0
GNS2_k127_3346879_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 3.355e-206 655.0
GNS2_k127_3346879_3 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 391.0
GNS2_k127_3346879_4 phosphate transporter K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 356.0
GNS2_k127_3346879_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 296.0
GNS2_k127_3346879_6 ABC-2 family transporter protein K01990,K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001202 262.0
GNS2_k127_3346879_7 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000001915 181.0
GNS2_k127_3346879_8 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000145 105.0
GNS2_k127_335314_0 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 546.0
GNS2_k127_335314_1 chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 479.0
GNS2_k127_335314_10 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000009981 151.0
GNS2_k127_335314_11 Secreted repeat of unknown function - - - 0.000000000000000000000000000000000003317 146.0
GNS2_k127_335314_12 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000006033 140.0
GNS2_k127_335314_13 cellulase activity - - - 0.000000000000000000000000000000001032 148.0
GNS2_k127_335314_14 - - - - 0.00000000000000000000000000001646 126.0
GNS2_k127_335314_16 Ketosteroid isomerase-related protein - - - 0.000000000003091 73.0
GNS2_k127_335314_17 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000004822 71.0
GNS2_k127_335314_18 Pfam:DUF385 - - - 0.0005003 45.0
GNS2_k127_335314_2 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 357.0
GNS2_k127_335314_3 COG2303 Choline dehydrogenase and related flavoproteins K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 332.0
GNS2_k127_335314_4 D-arabinono-1,4-lactone oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002488 281.0
GNS2_k127_335314_5 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001264 251.0
GNS2_k127_335314_6 tRNA (guanine-N2-)-methyltransferase activity K00563,K00571,K07319,K18896 - 2.1.1.156,2.1.1.187,2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000001241 226.0
GNS2_k127_335314_7 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000005806 213.0
GNS2_k127_335314_8 - - - - 0.00000000000000000000000000000000000000000000000000431 190.0
GNS2_k127_335314_9 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000003717 171.0
GNS2_k127_3472946_0 Elongation factor G C-terminus K06207 - - 1.028e-284 886.0
GNS2_k127_3472946_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 548.0
GNS2_k127_3472946_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 503.0
GNS2_k127_3472946_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000001665 162.0
GNS2_k127_3472946_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000005975 141.0
GNS2_k127_3472946_5 Cold shock protein domain K03704 - - 0.000000000000000000000000003077 113.0
GNS2_k127_3604544_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.028e-229 728.0
GNS2_k127_3604544_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.173e-206 649.0
GNS2_k127_3604544_2 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 332.0
GNS2_k127_3604544_3 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000000000000469 225.0
GNS2_k127_3604544_4 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.0000000000000000007252 97.0
GNS2_k127_3604544_5 Belongs to the ompA family K20276 - - 0.00000000005267 73.0
GNS2_k127_3662485_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 372.0
GNS2_k127_3662485_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000003262 199.0
GNS2_k127_3662485_2 HEPN domain - - - 0.0000000000000000000000000164 113.0
GNS2_k127_3662485_3 Nucleotidyltransferase domain - - - 0.00000000006855 69.0
GNS2_k127_3705484_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 602.0
GNS2_k127_3705484_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 428.0
GNS2_k127_3705484_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 421.0
GNS2_k127_3705484_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000001083 149.0
GNS2_k127_3705484_4 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000668 131.0
GNS2_k127_3909962_0 Belongs to the thiolase family - - - 4.566e-198 623.0
GNS2_k127_3909962_1 Belongs to the long-chain O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 569.0
GNS2_k127_3909962_10 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000001865 258.0
GNS2_k127_3909962_11 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000009874 219.0
GNS2_k127_3909962_12 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000000000000000000000000000000000000000000493 197.0
GNS2_k127_3909962_13 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000003904 182.0
GNS2_k127_3909962_14 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000001251 157.0
GNS2_k127_3909962_15 Thioredoxin - - - 0.0000000000000000000000000000000000001936 150.0
GNS2_k127_3909962_16 Thioesterase superfamily - - - 0.000000000000000000000000000004371 126.0
GNS2_k127_3909962_17 VKc - - - 0.0000000000000000000000000707 114.0
GNS2_k127_3909962_18 FUSC-like inner membrane protein yccS - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000004876 84.0
GNS2_k127_3909962_19 Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) - - - 0.0000000009068 67.0
GNS2_k127_3909962_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 578.0
GNS2_k127_3909962_3 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 464.0
GNS2_k127_3909962_4 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 422.0
GNS2_k127_3909962_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 353.0
GNS2_k127_3909962_6 impB/mucB/samB family C-terminal domain K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 344.0
GNS2_k127_3909962_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 339.0
GNS2_k127_3909962_8 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002247 289.0
GNS2_k127_3909962_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004698 249.0
GNS2_k127_3964263_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1231.0
GNS2_k127_3964263_1 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 608.0
GNS2_k127_3964263_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 245.0
GNS2_k127_3964263_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000136 226.0
GNS2_k127_3964263_4 - - - - 0.0000000000000000000000000000000000003036 149.0
GNS2_k127_3964263_5 oxidoreductase activity K01280 - 3.4.14.10 0.00000000000000000000000000000000002588 150.0
GNS2_k127_3964263_7 - - - - 0.00001411 55.0
GNS2_k127_3997242_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 407.0
GNS2_k127_3997242_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 336.0
GNS2_k127_3997242_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000003122 219.0
GNS2_k127_3997242_3 Ham1 family K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000003089 198.0
GNS2_k127_3997242_4 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000006788 186.0
GNS2_k127_3997242_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000001766 90.0
GNS2_k127_3997710_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 552.0
GNS2_k127_3997710_1 - - - - 0.00000000000000000000000000000000000000000000000000000001547 202.0
GNS2_k127_3997710_2 Acid phosphatase homologues - - - 0.00000000000000000000000000000000000000000000000000001432 195.0
GNS2_k127_3997710_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000000000000000001851 166.0
GNS2_k127_3997710_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000003014 109.0
GNS2_k127_3997710_6 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000006986 100.0
GNS2_k127_4000334_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.494e-234 745.0
GNS2_k127_4000334_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 486.0
GNS2_k127_4000334_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 340.0
GNS2_k127_4000334_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 291.0
GNS2_k127_4000334_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 286.0
GNS2_k127_4000334_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000004414 209.0
GNS2_k127_4000334_6 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000003004 189.0
GNS2_k127_4000334_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000005628 180.0
GNS2_k127_4000334_8 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000004863 121.0
GNS2_k127_4000334_9 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000003459 74.0
GNS2_k127_4005042_0 Type III restriction enzyme, res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 443.0
GNS2_k127_4005042_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000002911 174.0
GNS2_k127_4005042_2 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000002835 158.0
GNS2_k127_4028789_0 ABC transporter transmembrane region K06147 - - 1.772e-224 711.0
GNS2_k127_4028789_1 ABC transporter transmembrane region K06147 - - 4.923e-220 697.0
GNS2_k127_4028789_2 Glycosyl hydrolase family 92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 310.0
GNS2_k127_4068748_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 601.0
GNS2_k127_4068748_1 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 340.0
GNS2_k127_4068748_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 336.0
GNS2_k127_4068748_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000006857 261.0
GNS2_k127_4068748_4 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000003176 102.0
GNS2_k127_4068748_5 Unextendable partial coding region - - - 0.000000000000000000001808 94.0
GNS2_k127_4068748_7 Serine aminopeptidase, S33 - - - 0.00001094 59.0
GNS2_k127_4151503_0 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 299.0
GNS2_k127_4151503_1 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000001642 184.0
GNS2_k127_4153053_0 Aminotransferase class-V K00283 - 1.4.4.2 5.72e-198 623.0
GNS2_k127_4153053_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 476.0
GNS2_k127_4153053_10 Segregation and condensation complex subunit ScpB K06024 - - 0.000000000000000000000000000000000000000000000000000000000000001297 228.0
GNS2_k127_4153053_11 PFAM conserved K02069 - - 0.0000000000000000000000000000000000000000000000286 189.0
GNS2_k127_4153053_12 acetyltransferase - - - 0.000000000000000000000000000000000000000000002197 185.0
GNS2_k127_4153053_13 Belongs to the ABC transporter superfamily K02068 - - 0.000000000000000000000000000000000000000001285 166.0
GNS2_k127_4153053_14 Chorismate mutase type I K06208 - 5.4.99.5 0.000000000000000000000000000000000000001291 161.0
GNS2_k127_4153053_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009922 474.0
GNS2_k127_4153053_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 451.0
GNS2_k127_4153053_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 377.0
GNS2_k127_4153053_5 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 367.0
GNS2_k127_4153053_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001346 254.0
GNS2_k127_4153053_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007865 250.0
GNS2_k127_4153053_8 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000004036 239.0
GNS2_k127_4153053_9 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000003893 230.0
GNS2_k127_4153054_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 9.785e-199 629.0
GNS2_k127_4153054_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 503.0
GNS2_k127_4153054_2 Aminotransferase class-V K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 492.0
GNS2_k127_4153054_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 449.0
GNS2_k127_4153054_4 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000009097 233.0
GNS2_k127_4153054_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000001857 185.0
GNS2_k127_4153054_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000002696 158.0
GNS2_k127_4153054_7 POTRA domain, FtsQ-type K03589 - - 0.00000000001427 72.0
GNS2_k127_4167456_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1437.0
GNS2_k127_4167456_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 540.0
GNS2_k127_4167456_2 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K02823 - - 0.00000000000000000000000000000000000000000000000000000000002761 229.0
GNS2_k127_4167456_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000904 54.0
GNS2_k127_4181587_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 6.938e-252 792.0
GNS2_k127_4181587_1 P-loop ATPase protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 347.0
GNS2_k127_4181587_2 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000508 181.0
GNS2_k127_4209802_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 479.0
GNS2_k127_4209802_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 477.0
GNS2_k127_4209802_10 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000004297 239.0
GNS2_k127_4209802_11 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000004504 233.0
GNS2_k127_4209802_12 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000004057 210.0
GNS2_k127_4209802_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000255 208.0
GNS2_k127_4209802_14 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000000001074 179.0
GNS2_k127_4209802_15 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000678 168.0
GNS2_k127_4209802_16 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000002947 145.0
GNS2_k127_4209802_17 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000004221 124.0
GNS2_k127_4209802_18 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000003375 117.0
GNS2_k127_4209802_19 - - - - 0.000000000000000000003068 99.0
GNS2_k127_4209802_2 RNB K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 470.0
GNS2_k127_4209802_20 Divergent 4Fe-4S mono-cluster - - - 0.0000113 55.0
GNS2_k127_4209802_3 ATPases associated with a variety of cellular activities K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 337.0
GNS2_k127_4209802_4 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 355.0
GNS2_k127_4209802_5 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 307.0
GNS2_k127_4209802_6 pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 325.0
GNS2_k127_4209802_7 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 305.0
GNS2_k127_4209802_8 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009199 289.0
GNS2_k127_4209802_9 ApbE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003023 277.0
GNS2_k127_4266730_0 Glycosyl hydrolases family 15 - - - 7.601e-243 767.0
GNS2_k127_4266730_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 397.0
GNS2_k127_4266730_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 342.0
GNS2_k127_4266730_3 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 301.0
GNS2_k127_4266730_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007934 258.0
GNS2_k127_4266730_5 acetyltransferase - - - 0.0000000000000000000000000004656 118.0
GNS2_k127_4266730_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000836 111.0
GNS2_k127_4266730_7 Peptidase family M23 - - - 0.00000000000000000000004717 106.0
GNS2_k127_4266730_8 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000006969 87.0
GNS2_k127_4346844_0 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 349.0
GNS2_k127_4346844_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 330.0
GNS2_k127_4346844_2 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000002105 101.0
GNS2_k127_4346844_3 ATPase P-type (Transporting), HAD superfamily, subfamily IC K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 0.00000002369 57.0
GNS2_k127_4350106_0 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0000000000000000000000000000000000000000000000000000001774 203.0
GNS2_k127_4370824_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1035.0
GNS2_k127_4370824_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 3.415e-263 841.0
GNS2_k127_4370824_10 - - - - 0.000000000000000000000000000000000000000000000000000000000004567 220.0
GNS2_k127_4370824_11 Bacterial sugar transferase K16566 - - 0.00000000000000000000000000000000000000000000000000000000001699 214.0
GNS2_k127_4370824_12 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000168 209.0
GNS2_k127_4370824_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000008712 209.0
GNS2_k127_4370824_14 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000007899 186.0
GNS2_k127_4370824_15 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000001308 188.0
GNS2_k127_4370824_16 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000007411 190.0
GNS2_k127_4370824_17 - - - - 0.00000000000000000000000000000003424 136.0
GNS2_k127_4370824_2 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 505.0
GNS2_k127_4370824_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 458.0
GNS2_k127_4370824_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 421.0
GNS2_k127_4370824_5 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 360.0
GNS2_k127_4370824_6 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 343.0
GNS2_k127_4370824_7 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 317.0
GNS2_k127_4370824_8 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002951 254.0
GNS2_k127_4370824_9 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000002496 232.0
GNS2_k127_4374663_0 Cytochrome P450 - - - 2.865e-209 681.0
GNS2_k127_4374663_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 412.0
GNS2_k127_4374663_2 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 305.0
GNS2_k127_4374663_3 Alanine racemase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001854 226.0
GNS2_k127_4374663_4 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000001129 133.0
GNS2_k127_4374663_5 general secretion pathway protein - - - 0.00009277 45.0
GNS2_k127_4454898_0 Glutamate synthase central domain K00265 - 1.4.1.13,1.4.1.14 0.0 1490.0
GNS2_k127_4454898_1 - - - - 0.000000000000000000005131 94.0
GNS2_k127_4454898_2 SnoaL-like polyketide cyclase - - - 0.0000000007885 68.0
GNS2_k127_4454898_3 Cupin domain - - - 0.00000002794 61.0
GNS2_k127_4474935_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 463.0
GNS2_k127_4474935_1 Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000008745 238.0
GNS2_k127_4474935_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000002066 150.0
GNS2_k127_4474935_3 - - - - 0.00000000000000000001449 102.0
GNS2_k127_4575235_0 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 319.0
GNS2_k127_4575235_1 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 308.0
GNS2_k127_4575235_2 3'-5' exonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004703 286.0
GNS2_k127_4575235_3 Recombinase - - - 0.0000000000008116 76.0
GNS2_k127_4575235_4 Recombinase - - - 0.0000001815 60.0
GNS2_k127_4618466_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.316e-239 765.0
GNS2_k127_4618466_1 Glycosyl hydrolase family 92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 439.0
GNS2_k127_4618466_2 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 351.0
GNS2_k127_4618466_3 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 335.0
GNS2_k127_4618466_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 319.0
GNS2_k127_4618466_5 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000111 255.0
GNS2_k127_4618466_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000006747 193.0
GNS2_k127_4618466_7 ) H( ) antiporter that extrudes sodium in exchange for external protons - - - 0.0000000000000000000000000000000000000007408 171.0
GNS2_k127_4618466_8 GtrA-like protein - - - 0.0000000000000000000000000000000000002474 147.0
GNS2_k127_4618466_9 PFAM Helix-turn-helix - - - 0.0000000002039 64.0
GNS2_k127_4650223_0 Anthranilate synthase component I, N terminal region K01665,K13950 - 2.6.1.85 3.35e-206 666.0
GNS2_k127_4650223_1 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 508.0
GNS2_k127_4650223_10 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000045 268.0
GNS2_k127_4650223_11 including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004473 237.0
GNS2_k127_4650223_12 L-lysine 6-monooxygenase (NADPH-requiring) K04793 - - 0.000000000000000000000000000000000000000000000000000000000002605 226.0
GNS2_k127_4650223_13 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000008107 212.0
GNS2_k127_4650223_14 Pfam NUDIX - - - 0.000000000000000000000000000000000000000000000001067 182.0
GNS2_k127_4650223_15 - - - - 0.0000000000000000000000000000000000000000000007768 169.0
GNS2_k127_4650223_16 Transcription elongation factor, N-terminal K03624 - - 0.00000000000000000000000000000000000000002009 160.0
GNS2_k127_4650223_17 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000001269 137.0
GNS2_k127_4650223_18 - - - - 0.0000000000000000000000000003996 123.0
GNS2_k127_4650223_19 2TM domain - - - 0.0000000000000000000002233 104.0
GNS2_k127_4650223_2 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 411.0
GNS2_k127_4650223_20 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000005491 92.0
GNS2_k127_4650223_21 Chorismate mutase K04092,K04782 - 4.2.99.21,5.4.99.5 0.00000000000002875 85.0
GNS2_k127_4650223_22 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02045,K06857,K11072 - 3.6.3.25,3.6.3.31,3.6.3.55 0.0000003307 54.0
GNS2_k127_4650223_23 RDD family - - - 0.0002317 53.0
GNS2_k127_4650223_3 PFAM cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 411.0
GNS2_k127_4650223_4 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 387.0
GNS2_k127_4650223_5 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 376.0
GNS2_k127_4650223_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 387.0
GNS2_k127_4650223_7 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 358.0
GNS2_k127_4650223_8 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 342.0
GNS2_k127_4650223_9 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529,K18088,K18090 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 307.0
GNS2_k127_4736353_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1134.0
GNS2_k127_4736353_1 Glutamate synthase - - - 9.722e-265 843.0
GNS2_k127_4736353_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 323.0
GNS2_k127_4736353_11 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
GNS2_k127_4736353_12 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001621 244.0
GNS2_k127_4736353_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000008998 176.0
GNS2_k127_4736353_14 PFAM DsrC family protein K11179 - - 0.00000000000000000000000000000000007465 149.0
GNS2_k127_4736353_15 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000004906 102.0
GNS2_k127_4736353_16 - - - - 0.0000000000000008517 81.0
GNS2_k127_4736353_17 transcriptional regulator - - - 0.0000000001528 64.0
GNS2_k127_4736353_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 4.525e-195 617.0
GNS2_k127_4736353_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 556.0
GNS2_k127_4736353_4 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 557.0
GNS2_k127_4736353_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 544.0
GNS2_k127_4736353_6 PFAM HipA domain protein K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 486.0
GNS2_k127_4736353_7 PFAM Glycosyl transferase, group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 450.0
GNS2_k127_4736353_8 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 391.0
GNS2_k127_4736353_9 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 381.0
GNS2_k127_4819588_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.119e-231 729.0
GNS2_k127_4819588_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 517.0
GNS2_k127_4819588_10 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000001124 267.0
GNS2_k127_4819588_11 Glyoxalase-like domain K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002993 264.0
GNS2_k127_4819588_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000126 261.0
GNS2_k127_4819588_13 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000159 258.0
GNS2_k127_4819588_14 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004296 244.0
GNS2_k127_4819588_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001339 239.0
GNS2_k127_4819588_16 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000177 223.0
GNS2_k127_4819588_17 - - - - 0.000000000000000000000000000000000000000000000000000000000002602 217.0
GNS2_k127_4819588_18 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000003396 201.0
GNS2_k127_4819588_19 Reverse transcriptase-like K03469,K22316 - 3.1.26.4,3.1.3.73 0.000000000000000000000000000000000000000001502 164.0
GNS2_k127_4819588_2 PFAM magnesium chelatase K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 442.0
GNS2_k127_4819588_20 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000001502 114.0
GNS2_k127_4819588_21 Transposase IS66 family - - - 0.000000000000000000000002662 106.0
GNS2_k127_4819588_22 - - - - 0.00000000000000000009906 97.0
GNS2_k127_4819588_23 Belongs to the UPF0109 family K06960 - - 0.0000000000000000004607 91.0
GNS2_k127_4819588_24 Belongs to the UPF0102 family K07460 - - 0.000000000000000002085 89.0
GNS2_k127_4819588_25 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000001621 84.0
GNS2_k127_4819588_27 peptidyl-tyrosine sulfation - - - 0.00000000000001825 84.0
GNS2_k127_4819588_28 - - - - 0.00000000000007671 80.0
GNS2_k127_4819588_29 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000001448 60.0
GNS2_k127_4819588_3 RNA polymerase sigma factor K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 366.0
GNS2_k127_4819588_30 PFAM Uncharacterised protein family UPF0150 - - - 0.00000005116 59.0
GNS2_k127_4819588_31 Arm DNA-binding domain - - - 0.0001251 51.0
GNS2_k127_4819588_4 Pfam:DUF955 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 360.0
GNS2_k127_4819588_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 344.0
GNS2_k127_4819588_6 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 325.0
GNS2_k127_4819588_7 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 329.0
GNS2_k127_4819588_8 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 322.0
GNS2_k127_4819588_9 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 285.0
GNS2_k127_4856899_0 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 500.0
GNS2_k127_4856899_1 Exonuclease VII, large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 447.0
GNS2_k127_4856899_2 Colicin V production protein - - - 0.000000000000000000000000000000012 130.0
GNS2_k127_4856899_3 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000004167 126.0
GNS2_k127_4856899_4 Exonuclease VII small subunit - - - 0.000000000000000000001064 96.0
GNS2_k127_4884616_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.643e-269 843.0
GNS2_k127_4884616_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 434.0
GNS2_k127_4884616_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 334.0
GNS2_k127_4884616_3 Protein of unknown function (DUF3352) - - - 0.00000000000000000000000000000000001427 155.0
GNS2_k127_4884616_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000006265 115.0
GNS2_k127_4924222_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1135.0
GNS2_k127_4924222_1 Branched-chain amino acid transport system / permease component K10544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 447.0
GNS2_k127_4924222_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 422.0
GNS2_k127_4924222_3 Periplasmic binding protein domain K10543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 412.0
GNS2_k127_4924222_4 ABC transporter K02056,K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 326.0
GNS2_k127_4932844_0 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 2.098e-239 742.0
GNS2_k127_4932844_1 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 1.572e-221 700.0
GNS2_k127_4932844_2 lactate/malate dehydrogenase, alpha/beta C-terminal domain K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 491.0
GNS2_k127_4932844_3 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 419.0
GNS2_k127_4932844_4 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 420.0
GNS2_k127_4932844_5 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 382.0
GNS2_k127_4932844_6 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 334.0
GNS2_k127_4932844_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007616 286.0
GNS2_k127_4932844_8 Transposase - - - 0.00000000000001546 79.0
GNS2_k127_4932844_9 Fatty acid hydroxylase superfamily - - - 0.000000003721 57.0
GNS2_k127_4941577_0 Thiolase, C-terminal domain K00632 - 2.3.1.16 2.66e-198 624.0
GNS2_k127_4941577_1 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 540.0
GNS2_k127_4941577_10 Iron-containing alcohol dehydrogenase - - - 0.000000000000002233 80.0
GNS2_k127_4941577_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000009105 70.0
GNS2_k127_4941577_12 Domain of unknown function (DUF4383) - - - 0.0000000003086 67.0
GNS2_k127_4941577_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 543.0
GNS2_k127_4941577_3 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 496.0
GNS2_k127_4941577_4 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002905 265.0
GNS2_k127_4941577_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009282 233.0
GNS2_k127_4941577_6 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000001028 217.0
GNS2_k127_4941577_7 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000004295 159.0
GNS2_k127_4941577_8 Periplasmic binding protein K02016 - - 0.0000000000000000000000000007069 119.0
GNS2_k127_4941577_9 - - - - 0.000000000000000001048 89.0
GNS2_k127_4964744_0 Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 7.776e-270 842.0
GNS2_k127_4964744_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.28e-233 730.0
GNS2_k127_4964744_10 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 374.0
GNS2_k127_4964744_11 Thought to be involved in fatty acid degradation. FadB and FadA are the alpha and beta subunits of the multifunctional enzyme complex of the fatty acid degradation cycle K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 359.0
GNS2_k127_4964744_12 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 316.0
GNS2_k127_4964744_13 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000008968 275.0
GNS2_k127_4964744_14 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000006342 233.0
GNS2_k127_4964744_15 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000000000000000000000004854 199.0
GNS2_k127_4964744_16 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000001185 164.0
GNS2_k127_4964744_17 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000001259 162.0
GNS2_k127_4964744_18 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) - - - 0.000000000000000000000000000000000007735 154.0
GNS2_k127_4964744_19 COG2931 RTX toxins and related Ca2 -binding - - - 0.0000000000005978 78.0
GNS2_k127_4964744_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 6.541e-196 624.0
GNS2_k127_4964744_20 PFAM NAD-dependent epimerase dehydratase K06118 - 3.13.1.1 0.00001355 48.0
GNS2_k127_4964744_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 547.0
GNS2_k127_4964744_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 473.0
GNS2_k127_4964744_5 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 467.0
GNS2_k127_4964744_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 448.0
GNS2_k127_4964744_7 chorismate binding enzyme K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 456.0
GNS2_k127_4964744_8 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 424.0
GNS2_k127_4964744_9 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 423.0
GNS2_k127_499671_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 537.0
GNS2_k127_499671_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 501.0
GNS2_k127_499671_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000003607 243.0
GNS2_k127_499671_4 - - - - 0.00003285 55.0
GNS2_k127_5130159_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.231e-213 683.0
GNS2_k127_5130159_1 Hydantoinase B/oxoprolinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 627.0
GNS2_k127_5130159_10 - - - - 0.00000000000525 70.0
GNS2_k127_5130159_11 sequence-specific DNA binding K15546,K15773 - - 0.000000003769 61.0
GNS2_k127_5130159_12 - - - - 0.0000001244 57.0
GNS2_k127_5130159_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 603.0
GNS2_k127_5130159_3 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 436.0
GNS2_k127_5130159_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 303.0
GNS2_k127_5130159_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 296.0
GNS2_k127_5130159_6 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002523 267.0
GNS2_k127_5130159_7 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003043 237.0
GNS2_k127_5130159_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000005543 102.0
GNS2_k127_5130159_9 Endoribonuclease L-PSP - - - 0.0000000000000000004339 92.0
GNS2_k127_5167400_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 6.477e-209 658.0
GNS2_k127_5167400_1 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 418.0
GNS2_k127_5167400_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 334.0
GNS2_k127_5167400_3 DbpA RNA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000115 283.0
GNS2_k127_5167400_4 - - - - 0.000000000002576 74.0
GNS2_k127_5167400_5 - - - - 0.00000000002006 74.0
GNS2_k127_5169816_0 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 597.0
GNS2_k127_5169816_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 510.0
GNS2_k127_5169816_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 494.0
GNS2_k127_5169816_3 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000001322 214.0
GNS2_k127_5169816_4 - - - - 0.000000000000000000005042 94.0
GNS2_k127_5169816_5 - - - - 0.0000000000001459 74.0
GNS2_k127_5236256_0 Glycosyltransferase Family 4 - - - 4.703e-290 912.0
GNS2_k127_5236256_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.163e-288 904.0
GNS2_k127_5236256_10 CHAD domain - - - 0.000000000000000000000001942 108.0
GNS2_k127_5236256_2 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 480.0
GNS2_k127_5236256_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 361.0
GNS2_k127_5236256_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001265 285.0
GNS2_k127_5236256_5 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000133 265.0
GNS2_k127_5236256_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002924 265.0
GNS2_k127_5236256_7 binding-protein-dependent transport systems inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001921 263.0
GNS2_k127_5236256_8 Ppx GppA phosphatase K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000001406 229.0
GNS2_k127_5236256_9 CHAD domain - - - 0.000000000000000000000000000005503 124.0
GNS2_k127_5280199_0 Cytochrome C and Quinol oxidase polypeptide I - - - 5.504e-283 882.0
GNS2_k127_5280199_1 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001174 238.0
GNS2_k127_5280199_2 I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000004565 199.0
GNS2_k127_5280199_3 amino acid transport K03294 - - 0.000000000000000005203 89.0
GNS2_k127_5314029_0 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 553.0
GNS2_k127_5314029_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 441.0
GNS2_k127_5314029_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 362.0
GNS2_k127_5335557_0 Cytochrome b K03887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 370.0
GNS2_k127_5335557_1 Belongs to the FPP GGPP synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 323.0
GNS2_k127_5335557_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
GNS2_k127_5335557_3 Cytochrome b subunit of the bc K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 308.0
GNS2_k127_5335557_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000001079 235.0
GNS2_k127_5335557_5 - - - - 0.0000000000000000000001279 106.0
GNS2_k127_5335557_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000003915 73.0
GNS2_k127_537799_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 560.0
GNS2_k127_537799_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 520.0
GNS2_k127_537799_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000002439 127.0
GNS2_k127_537799_11 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000001353 78.0
GNS2_k127_537799_12 Diguanylate cyclase - - - 0.00000265 58.0
GNS2_k127_537799_2 Binding-protein-dependent transport system inner membrane component K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 390.0
GNS2_k127_537799_3 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009424 379.0
GNS2_k127_537799_4 binding-protein-dependent transport systems inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 315.0
GNS2_k127_537799_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002501 285.0
GNS2_k127_537799_6 MerR family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000004678 231.0
GNS2_k127_537799_7 regulatory protein, arsR K03892 - - 0.000000000000000000000000000000000000000000000000000000225 196.0
GNS2_k127_537799_8 Low molecular weight phosphatase family - - - 0.0000000000000000000000000000000000000000000000000003909 189.0
GNS2_k127_537799_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000008382 118.0
GNS2_k127_5402742_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 555.0
GNS2_k127_5402742_1 AsnC-type helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 497.0
GNS2_k127_5402742_2 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000001429 240.0
GNS2_k127_5402742_3 Cytochrome b K03887 - - 0.0000000000000000000000000000000000000000000000000000000000000000008115 243.0
GNS2_k127_5402742_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000007366 215.0
GNS2_k127_5402742_5 - - - - 0.0000000000000000000000000008058 117.0
GNS2_k127_5430663_0 Homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 530.0
GNS2_k127_5430663_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 502.0
GNS2_k127_5430663_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000004197 141.0
GNS2_k127_5430663_11 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.0000000000000000000000000001185 126.0
GNS2_k127_5430663_13 - - - - 0.0000005755 58.0
GNS2_k127_5430663_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 462.0
GNS2_k127_5430663_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 407.0
GNS2_k127_5430663_4 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 363.0
GNS2_k127_5430663_5 Putative cell wall binding repeat 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 314.0
GNS2_k127_5430663_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 322.0
GNS2_k127_5430663_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002772 258.0
GNS2_k127_5430663_8 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008773 255.0
GNS2_k127_5430663_9 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000908 242.0
GNS2_k127_5434279_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.161e-257 805.0
GNS2_k127_5434279_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 428.0
GNS2_k127_5434279_10 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000002835 165.0
GNS2_k127_5434279_11 Copper transport outer membrane protein, MctB - - - 0.00000000000000000008138 100.0
GNS2_k127_5434279_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 444.0
GNS2_k127_5434279_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 409.0
GNS2_k127_5434279_4 Thiamin pyrophosphokinase, catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 409.0
GNS2_k127_5434279_5 Peptidase dimerisation domain K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 343.0
GNS2_k127_5434279_6 Protein of unknown function (DUF3866) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 329.0
GNS2_k127_5434279_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 291.0
GNS2_k127_5434279_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000003866 265.0
GNS2_k127_5434279_9 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001124 262.0
GNS2_k127_556990_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.05e-221 695.0
GNS2_k127_556990_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 3.082e-198 631.0
GNS2_k127_5570058_0 Flavin-binding monooxygenase-like K10215 - - 3.878e-218 688.0
GNS2_k127_5570058_1 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 494.0
GNS2_k127_5570058_10 toxin-antitoxin pair type II binding - - - 0.00001565 51.0
GNS2_k127_5570058_11 Phosphoesterase family K01114 - 3.1.4.3 0.00006302 56.0
GNS2_k127_5570058_12 - - - - 0.0004335 46.0
GNS2_k127_5570058_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 407.0
GNS2_k127_5570058_3 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001701 297.0
GNS2_k127_5570058_4 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000002603 147.0
GNS2_k127_5570058_5 - - - - 0.00000000000000000000001008 102.0
GNS2_k127_5570058_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.0000000000000000003396 95.0
GNS2_k127_5570058_7 Protein of unknown function (DUF2630) - - - 0.00000000000001068 76.0
GNS2_k127_5570058_8 - - - - 0.0000000000001512 77.0
GNS2_k127_5570058_9 - - - - 0.0000000000001897 76.0
GNS2_k127_5659853_0 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006578 469.0
GNS2_k127_5659853_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000006769 192.0
GNS2_k127_5659853_2 O-acyltransferase activity - - - 0.0000000000000000000000587 108.0
GNS2_k127_5659853_3 - - - - 0.000000000000000000006086 107.0
GNS2_k127_5659853_4 Archaeal Type IV pilin, N-terminal - - - 0.000005384 58.0
GNS2_k127_5659853_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0002332 50.0
GNS2_k127_5724754_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 586.0
GNS2_k127_5724754_1 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 569.0
GNS2_k127_5724754_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 552.0
GNS2_k127_5724754_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 344.0
GNS2_k127_5724754_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 340.0
GNS2_k127_5724754_5 CobB/CobQ-like glutamine amidotransferase domain K07009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 340.0
GNS2_k127_5724754_6 IPP transferase K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000008688 255.0
GNS2_k127_5724754_7 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000006168 243.0
GNS2_k127_5724754_8 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000001508 173.0
GNS2_k127_5724754_9 Methyltransferase domain - - - 0.0000000000000000007326 90.0
GNS2_k127_5954818_0 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 5.545e-197 631.0
GNS2_k127_5954818_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 611.0
GNS2_k127_5954818_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 463.0
GNS2_k127_5954818_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 331.0
GNS2_k127_5954818_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001213 277.0
GNS2_k127_5954818_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000001098 195.0
GNS2_k127_5954818_6 Thioredoxin-like - - - 0.000000000000000000000000000000001394 136.0
GNS2_k127_5954818_7 Cytochrome C biogenesis protein K02200 - - 0.00000000000000000000000000009048 128.0
GNS2_k127_5954818_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000001782 75.0
GNS2_k127_5954818_9 HemY domain protein K20276 - - 0.0000009869 57.0
GNS2_k127_595497_0 PD-(D/E)XK nuclease superfamily K03657 - 3.6.4.12 4.672e-233 752.0
GNS2_k127_595497_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000001673 221.0
GNS2_k127_5970551_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 3.955e-267 832.0
GNS2_k127_5970551_1 Pfam:HipA_N K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 545.0
GNS2_k127_5970551_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 432.0
GNS2_k127_5970551_3 Cysteine-rich domain K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 435.0
GNS2_k127_5970551_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 411.0
GNS2_k127_5970551_5 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000553 219.0
GNS2_k127_5970551_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000004033 121.0
GNS2_k127_5970551_7 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000006891 99.0
GNS2_k127_5971938_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 402.0
GNS2_k127_5971938_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 333.0
GNS2_k127_5971938_2 Peptidoglycan-binding domain 1 protein K08640 - 3.4.17.14 0.0000000000000000000000008377 110.0
GNS2_k127_5971938_3 PFAM metal-dependent phosphohydrolase, HD sub domain K09163 - - 0.00004461 47.0
GNS2_k127_5980341_0 Carboxyl transferase domain - - - 2.169e-267 829.0
GNS2_k127_5980341_1 Belongs to the group II decarboxylase family K01580 - 4.1.1.15 5.626e-245 761.0
GNS2_k127_5980341_10 antibiotic catabolic process - - - 0.00000000000000000000000000000000000000000000000000009169 208.0
GNS2_k127_5980341_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000003093 165.0
GNS2_k127_5980341_12 zinc ion binding K06204 - - 0.0000000000000000007832 91.0
GNS2_k127_5980341_13 - - - - 0.00000000000000004198 87.0
GNS2_k127_5980341_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000004887 81.0
GNS2_k127_5980341_15 - - - - 0.000002092 58.0
GNS2_k127_5980341_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.294e-234 744.0
GNS2_k127_5980341_3 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 494.0
GNS2_k127_5980341_4 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 417.0
GNS2_k127_5980341_5 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 405.0
GNS2_k127_5980341_6 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 391.0
GNS2_k127_5980341_7 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 310.0
GNS2_k127_5980341_8 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 298.0
GNS2_k127_5980341_9 TIGRFAM degV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 294.0
GNS2_k127_5989458_0 Amino acid permease K03294 - - 3.125e-213 679.0
GNS2_k127_5989458_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 557.0
GNS2_k127_5989458_2 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 372.0
GNS2_k127_5989458_3 Putative NAD(P)-binding K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 325.0
GNS2_k127_5989458_4 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006544 267.0
GNS2_k127_5989458_5 Putative NAD(P)-binding K03499 - - 0.00000000000000000000000000000000000000000000000000000007682 199.0
GNS2_k127_5989458_6 DUF218 domain - - - 0.00000000000000000000000000000000000000000000006418 184.0
GNS2_k127_5989458_7 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000006016 57.0
GNS2_k127_6005303_0 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 443.0
GNS2_k127_6005303_1 abc transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 347.0
GNS2_k127_6005303_2 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001811 272.0
GNS2_k127_6005303_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000006226 241.0
GNS2_k127_6005303_4 Involved in multi-copper enzyme maturation, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009247 254.0
GNS2_k127_6005303_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000001226 233.0
GNS2_k127_6005303_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000002138 154.0
GNS2_k127_6014406_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 583.0
GNS2_k127_6014406_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 388.0
GNS2_k127_6014406_12 translation initiation factor activity K06996 - - 0.00000007956 58.0
GNS2_k127_6014406_13 DNA-binding transcription factor activity - - - 0.0000001212 58.0
GNS2_k127_6014406_2 Glycoside-hydrolase family GH114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004078 271.0
GNS2_k127_6014406_3 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000000000000000000000000003508 203.0
GNS2_k127_6014406_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000001149 207.0
GNS2_k127_6014406_5 YCII-related domain - - - 0.0000000000000000000000000000000000000000000001465 171.0
GNS2_k127_6014406_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000005879 164.0
GNS2_k127_6014406_7 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000166 160.0
GNS2_k127_6014406_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000003783 130.0
GNS2_k127_6014406_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000002553 99.0
GNS2_k127_6014579_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 561.0
GNS2_k127_6014579_1 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001488 258.0
GNS2_k127_6014579_2 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000542 215.0
GNS2_k127_6014579_3 conserved protein (DUF2267) - - - 0.00000000000000000000000000000000000000001447 156.0
GNS2_k127_6014579_4 MacB-like periplasmic core domain - - - 0.0000000000000000000000000002654 128.0
GNS2_k127_6014579_5 Dodecin K09165 - - 0.00000000000000000000746 94.0
GNS2_k127_6014579_6 PIN domain - - - 0.0000000000000859 74.0
GNS2_k127_6014579_7 cell adhesion involved in biofilm formation K13735 - - 0.000000004811 67.0
GNS2_k127_6014579_8 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0003382 52.0
GNS2_k127_6042094_0 GMC oxidoreductase K03333 - 1.1.3.6 2.275e-277 861.0
GNS2_k127_6042094_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 605.0
GNS2_k127_6042094_10 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000001423 209.0
GNS2_k127_6042094_11 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000002864 199.0
GNS2_k127_6042094_12 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000001571 186.0
GNS2_k127_6042094_13 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000008905 184.0
GNS2_k127_6042094_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000003453 155.0
GNS2_k127_6042094_15 diguanylate cyclase - - - 0.00000000000000000000000000000000001901 154.0
GNS2_k127_6042094_16 Rubredoxin - - - 0.000000000000000000000000006594 110.0
GNS2_k127_6042094_17 biotin lipoyl attachment domain-containing protein K02160 - - 0.000000000000000000000001346 114.0
GNS2_k127_6042094_18 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000001828 69.0
GNS2_k127_6042094_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 584.0
GNS2_k127_6042094_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 503.0
GNS2_k127_6042094_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 479.0
GNS2_k127_6042094_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001744 267.0
GNS2_k127_6042094_6 glycoside hydrolase, family K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000002963 246.0
GNS2_k127_6042094_7 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001177 238.0
GNS2_k127_6042094_8 Peroxide stress protein YaaA - - - 0.00000000000000000000000000000000000000000000000000000000000005077 221.0
GNS2_k127_6042094_9 AAA domain K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000002329 211.0
GNS2_k127_6055227_0 PFAM metal-dependent phosphohydrolase, HD sub domain K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 364.0
GNS2_k127_6055227_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 343.0
GNS2_k127_6055227_2 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000007658 227.0
GNS2_k127_6055227_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000001094 107.0
GNS2_k127_6076767_0 CoA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 401.0
GNS2_k127_6076767_1 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 334.0
GNS2_k127_6076767_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000004139 96.0
GNS2_k127_6120537_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 499.0
GNS2_k127_6120537_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000003511 184.0
GNS2_k127_6120537_2 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000001116 185.0
GNS2_k127_6120537_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000007731 162.0
GNS2_k127_6123733_0 Aminotransferase class I and II K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 589.0
GNS2_k127_6123733_1 Protein export membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 450.0
GNS2_k127_6123733_10 B3 4 domain protein - - - 0.00000000000000000000000000000000000000000000000001158 190.0
GNS2_k127_6123733_11 - - - - 0.00000000000000000000000000000000001917 141.0
GNS2_k127_6123733_13 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000001152 111.0
GNS2_k127_6123733_14 - - - - 0.0000000000000000005188 92.0
GNS2_k127_6123733_15 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000002503 85.0
GNS2_k127_6123733_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 439.0
GNS2_k127_6123733_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008706 443.0
GNS2_k127_6123733_4 NMT1/THI5 like K15598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 293.0
GNS2_k127_6123733_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 290.0
GNS2_k127_6123733_6 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001832 254.0
GNS2_k127_6123733_7 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000008434 244.0
GNS2_k127_6123733_8 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000744 223.0
GNS2_k127_6123733_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
GNS2_k127_612514_0 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 298.0
GNS2_k127_612514_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000003172 195.0
GNS2_k127_612514_2 Membrane - - - 0.000107 49.0
GNS2_k127_612514_3 cellulase activity - - - 0.0004132 44.0
GNS2_k127_6148957_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 568.0
GNS2_k127_6148957_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 569.0
GNS2_k127_6148957_2 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 531.0
GNS2_k127_6148957_3 4Fe-4S dicluster domain K18930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 458.0
GNS2_k127_6148957_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 394.0
GNS2_k127_6148957_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 356.0
GNS2_k127_6148957_6 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000009897 245.0
GNS2_k127_6148957_7 Transglycosylase SLT domain - - - 0.0000000000000000000000000002147 134.0
GNS2_k127_6148957_8 - - - - 0.000001277 56.0
GNS2_k127_6189117_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.208e-215 679.0
GNS2_k127_6189117_1 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000001878 241.0
GNS2_k127_6189117_2 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000000000000000000000000000000000000000000001289 240.0
GNS2_k127_6189117_3 PFAM Protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000005029 208.0
GNS2_k127_6189117_4 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000006499 225.0
GNS2_k127_6189117_5 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000001175 211.0
GNS2_k127_6189117_6 polyketide cyclase - - - 0.000000000000000000000000000000000000000000000004758 177.0
GNS2_k127_6189117_7 ASCH domain - - - 0.00000000000000000000000000000000000000000003765 168.0
GNS2_k127_6189117_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000001196 129.0
GNS2_k127_6193031_0 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 549.0
GNS2_k127_6193031_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 323.0
GNS2_k127_6193031_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000007109 193.0
GNS2_k127_6193031_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000008689 154.0
GNS2_k127_6193031_4 - - - - 0.00000000000000000000000000003972 130.0
GNS2_k127_6193031_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000002316 115.0
GNS2_k127_6193031_6 Mechanosensitive ion channel - - - 0.00000000000000000000000001663 113.0
GNS2_k127_6193031_7 CAAX protease self-immunity K07052 - - 0.000000000000002684 86.0
GNS2_k127_6193031_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000003686 71.0
GNS2_k127_6233618_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 8.994e-306 960.0
GNS2_k127_6233618_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 555.0
GNS2_k127_6233618_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000003609 112.0
GNS2_k127_6233618_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 486.0
GNS2_k127_6233618_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 477.0
GNS2_k127_6233618_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 346.0
GNS2_k127_6233618_5 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 321.0
GNS2_k127_6233618_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000001568 254.0
GNS2_k127_6233618_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000004437 194.0
GNS2_k127_6233618_8 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000000000000000000007444 191.0
GNS2_k127_6233618_9 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000006754 163.0
GNS2_k127_6251031_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 428.0
GNS2_k127_6251031_1 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 406.0
GNS2_k127_6251031_2 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 397.0
GNS2_k127_6251031_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 352.0
GNS2_k127_6251031_4 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002315 270.0
GNS2_k127_6251031_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000002155 220.0
GNS2_k127_6251031_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000002076 196.0
GNS2_k127_6251031_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000001345 134.0
GNS2_k127_6251031_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000004324 136.0
GNS2_k127_6251031_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000004647 128.0
GNS2_k127_6265554_0 drug exporters of the RND superfamily K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 591.0
GNS2_k127_6265554_1 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 383.0
GNS2_k127_6265554_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000004531 214.0
GNS2_k127_6265554_3 Virulence activator alpha C-term - - - 0.000000000000000000000001303 110.0
GNS2_k127_6265554_4 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000004397 108.0
GNS2_k127_6428494_0 Transmembrane protein of unknown function (DUF3556) - - - 1.766e-221 701.0
GNS2_k127_6428494_1 FAD dependent oxidoreductase - - - 2.209e-214 674.0
GNS2_k127_6428494_10 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000007245 182.0
GNS2_k127_6428494_11 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000004248 192.0
GNS2_k127_6428494_12 PFAM NADH Ubiquinone - - - 0.0000000000000000000000000000000000002913 149.0
GNS2_k127_6428494_13 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000155 115.0
GNS2_k127_6428494_14 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000006602 113.0
GNS2_k127_6428494_15 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.0000000000002735 80.0
GNS2_k127_6428494_17 cellulase activity - - - 0.0000000001969 74.0
GNS2_k127_6428494_18 TIGRFAM deazaflavin-dependent nitroreductase family protein - - - 0.00000001045 59.0
GNS2_k127_6428494_2 Phytoene dehydrogenase-like oxidoreductase - - - 2.897e-201 641.0
GNS2_k127_6428494_3 HipA-like C-terminal domain K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 440.0
GNS2_k127_6428494_4 Proton-conducting membrane transporter K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 385.0
GNS2_k127_6428494_5 PFAM Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006701 292.0
GNS2_k127_6428494_6 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001808 261.0
GNS2_k127_6428494_7 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000004899 228.0
GNS2_k127_6428494_8 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12141 - - 0.00000000000000000000000000000000000000000000000000000000004372 223.0
GNS2_k127_6428494_9 Pfam:DUF385 - - - 0.000000000000000000000000000000000000000000000000000000001781 205.0
GNS2_k127_6436757_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 491.0
GNS2_k127_6436757_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 441.0
GNS2_k127_6436757_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000003515 228.0
GNS2_k127_6436757_3 S-adenosylmethionine synthetase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000002264 198.0
GNS2_k127_6436757_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000001643 191.0
GNS2_k127_6469132_0 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.0 1045.0
GNS2_k127_6469132_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 3.344e-280 876.0
GNS2_k127_6469132_2 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 605.0
GNS2_k127_6469132_3 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000023 264.0
GNS2_k127_6469132_4 acetyltransferase - - - 0.0000000000000003659 88.0
GNS2_k127_6504916_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 415.0
GNS2_k127_6504916_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 402.0
GNS2_k127_6504916_2 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 365.0
GNS2_k127_6504916_3 HAD-superfamily hydrolase subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003344 282.0
GNS2_k127_6504916_4 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000000000000000000003679 190.0
GNS2_k127_6504916_5 Sulfatase - - - 0.000000000000000000000000000000000000314 151.0
GNS2_k127_6550018_0 PFAM NADH Ubiquinone plastoquinone (complex I) K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 615.0
GNS2_k127_6550018_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 309.0
GNS2_k127_6550018_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 319.0
GNS2_k127_6550018_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - - 0.000000000000000000000000000000000000000003905 170.0
GNS2_k127_6550018_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000002341 143.0
GNS2_k127_6550018_5 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000002329 89.0
GNS2_k127_66782_0 Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms K00122 - 1.17.1.9 1.758e-217 679.0
GNS2_k127_66782_1 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 523.0
GNS2_k127_66782_2 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 416.0
GNS2_k127_66782_3 Peptidase C26 - - - 0.00000000000000000000000000000000003153 143.0
GNS2_k127_66782_4 arsR family - - - 0.000000000000000000000000000000001088 135.0
GNS2_k127_66782_5 Methyltransferase domain - - - 0.000000000000000000000000000000005563 131.0
GNS2_k127_6924914_0 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 379.0
GNS2_k127_6924914_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 296.0
GNS2_k127_6924914_2 transferase activity, transferring amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001181 260.0
GNS2_k127_6924914_3 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000001303 216.0
GNS2_k127_6924914_4 Protein of unknown function (DUF3105) - - - 0.00000000000000000000000002341 118.0
GNS2_k127_6924914_5 Acetyltransferase (GNAT) domain - - - 0.0000000002353 68.0
GNS2_k127_6954325_0 Aldehyde dehydrogenase family K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 458.0
GNS2_k127_6954325_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 441.0
GNS2_k127_6954325_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000006188 223.0
GNS2_k127_6954325_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000205 189.0
GNS2_k127_6954325_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000118 121.0
GNS2_k127_6954325_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000001167 92.0
GNS2_k127_6954325_6 - - - - 0.00000000001257 74.0
GNS2_k127_6984409_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 458.0
GNS2_k127_6984409_1 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 329.0
GNS2_k127_6984409_10 - - - - 0.0000000000000000000000000000001076 131.0
GNS2_k127_6984409_11 Cytochrome c - - - 0.0000000000000000000000003981 120.0
GNS2_k127_6984409_12 Cysteine-rich secretory protein family - - - 0.00000000000000000003725 99.0
GNS2_k127_6984409_13 MacB-like periplasmic core domain K02004 - - 0.00000000000003623 80.0
GNS2_k127_6984409_2 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 335.0
GNS2_k127_6984409_3 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 293.0
GNS2_k127_6984409_4 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000003409 207.0
GNS2_k127_6984409_5 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000003385 199.0
GNS2_k127_6984409_6 HAD-superfamily hydrolase, subfamily IIA - - - 0.00000000000000000000000000000000000000000001742 171.0
GNS2_k127_6984409_7 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000005166 154.0
GNS2_k127_6984409_8 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000006361 152.0
GNS2_k127_6984409_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000003986 141.0
GNS2_k127_7018235_0 Anthranilate synthase component I, N terminal region K01665,K13950 - 2.6.1.85 5.647e-230 742.0
GNS2_k127_7018235_1 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 601.0
GNS2_k127_7018235_10 synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000002499 165.0
GNS2_k127_7018235_11 proline dehydrogenase activity - - - 0.00000000000000000000000000000000008984 153.0
GNS2_k127_7018235_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000618 144.0
GNS2_k127_7018235_13 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000000000000001214 106.0
GNS2_k127_7018235_14 YdjC-like protein - GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872 - 0.000000000000000001107 96.0
GNS2_k127_7018235_2 UDP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 518.0
GNS2_k127_7018235_3 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 461.0
GNS2_k127_7018235_4 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 416.0
GNS2_k127_7018235_5 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 306.0
GNS2_k127_7018235_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000191 280.0
GNS2_k127_7018235_7 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000004784 223.0
GNS2_k127_7018235_8 Glycosyltransferase, group 1 family protein - - - 0.000000000000000000000000000000000000000000000000002507 206.0
GNS2_k127_7018235_9 GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.0000000000000000000000000000000000000000002243 175.0
GNS2_k127_706400_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 592.0
GNS2_k127_706400_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 480.0
GNS2_k127_706400_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000009424 117.0
GNS2_k127_706400_11 Uncharacterised protein family (UPF0093) - - - 0.0000000000000000000000571 106.0
GNS2_k127_706400_12 response to nickel cation - - - 0.0000000000000002727 82.0
GNS2_k127_706400_13 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000001313 60.0
GNS2_k127_706400_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 377.0
GNS2_k127_706400_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 367.0
GNS2_k127_706400_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 294.0
GNS2_k127_706400_5 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005005 267.0
GNS2_k127_706400_6 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000003283 275.0
GNS2_k127_706400_7 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000005739 214.0
GNS2_k127_706400_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000004671 151.0
GNS2_k127_706400_9 Yqey-like protein K09117 - - 0.000000000000000000000000000000000001461 143.0
GNS2_k127_7075622_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 5.317e-225 705.0
GNS2_k127_7075622_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000006345 177.0
GNS2_k127_7075622_2 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000003564 154.0
GNS2_k127_7075622_3 MMPL family - - - 0.00000000000000000000000000002665 119.0
GNS2_k127_7075622_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000002958 98.0
GNS2_k127_7114652_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 461.0
GNS2_k127_7114652_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 359.0
GNS2_k127_7114652_2 Cell cycle protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 330.0
GNS2_k127_7114652_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000003664 190.0
GNS2_k127_7114652_4 PIN domain - - - 0.000000000000000000000000004455 115.0
GNS2_k127_7114652_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000009956 94.0
GNS2_k127_7114652_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000005172 77.0
GNS2_k127_7126853_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 1.39e-310 964.0
GNS2_k127_7126853_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 447.0
GNS2_k127_7126853_2 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 424.0
GNS2_k127_7126853_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 297.0
GNS2_k127_7126853_4 biosynthesis protein K08252 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000001157 256.0
GNS2_k127_7126853_5 Belongs to the glycosyl hydrolase 26 family - - - 0.0000000000000000000000000000000000000000000000000000000002179 216.0
GNS2_k127_7126853_6 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000000018 143.0
GNS2_k127_7126853_7 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000003183 131.0
GNS2_k127_7126853_8 - - - - 0.0000000000000000000000001322 117.0
GNS2_k127_7161061_0 Cytochrome C and Quinol oxidase polypeptide I - - - 2.336e-206 660.0
GNS2_k127_7161061_1 PFAM FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 605.0
GNS2_k127_7161061_10 - - - - 0.000003454 57.0
GNS2_k127_7161061_2 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 469.0
GNS2_k127_7161061_3 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000002444 241.0
GNS2_k127_7161061_4 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000004144 233.0
GNS2_k127_7161061_5 - - - - 0.0000000000000000000000000000000000000000000006373 175.0
GNS2_k127_7161061_6 PFAM Cytochrome c oxidase caa3-type, assembly factor CtaG-related - - - 0.00000000000000000000000000000000000000608 156.0
GNS2_k127_7161061_7 Protein of unknown function (DUF4242) - - - 0.0000000000000000000001708 107.0
GNS2_k127_7161061_8 SCO1/SenC K07152 - - 0.00000000000000000006896 98.0
GNS2_k127_7161061_9 nucleotidyltransferase activity - - - 0.00000006491 61.0
GNS2_k127_7187747_0 Found in ATP-dependent protease La (LON) K01338 - 3.4.21.53 0.0 1052.0
GNS2_k127_7187747_1 MMPL family K06994 - - 9.226e-194 629.0
GNS2_k127_7187747_2 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 448.0
GNS2_k127_7187747_3 Ribonucleotide reductase, small chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 406.0
GNS2_k127_7187747_4 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000002247 215.0
GNS2_k127_7187747_5 Membrane - - - 0.000000000000000000000000000000000000000000000000000000004672 225.0
GNS2_k127_7187747_6 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000006196 187.0
GNS2_k127_7187747_7 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000009853 161.0
GNS2_k127_7187747_8 - - - - 0.00000000000000000000000000005805 121.0
GNS2_k127_7194897_0 Uncharacterized protein family (UPF0051) K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 475.0
GNS2_k127_7194897_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 458.0
GNS2_k127_7194897_2 ATPases associated with a variety of cellular activities K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 399.0
GNS2_k127_7194897_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 296.0
GNS2_k127_7194897_4 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004953 263.0
GNS2_k127_7194897_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001915 226.0
GNS2_k127_7194897_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000004104 202.0
GNS2_k127_7194897_7 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000001976 169.0
GNS2_k127_7194897_8 Rieske 2Fe-2S iron-sulphur domain K05710 - - 0.0000000000000000000000000000000000000000007183 158.0
GNS2_k127_7214754_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 454.0
GNS2_k127_7214754_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 454.0
GNS2_k127_7214754_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 343.0
GNS2_k127_7214754_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000001238 240.0
GNS2_k127_7214754_4 Methyltransferase domain K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000005512 241.0
GNS2_k127_7214754_5 domain, Protein K01179 - 3.2.1.4 0.0006192 51.0
GNS2_k127_7243418_0 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 575.0
GNS2_k127_7243418_1 Glycosyl transferase, family 20 K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 405.0
GNS2_k127_7243418_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 377.0
GNS2_k127_7243418_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 338.0
GNS2_k127_7243418_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002994 259.0
GNS2_k127_7243418_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000004323 61.0
GNS2_k127_7259849_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 379.0
GNS2_k127_7259849_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008683 232.0
GNS2_k127_7259849_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000005936 57.0
GNS2_k127_7259849_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000003597 214.0
GNS2_k127_7259849_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000005534 195.0
GNS2_k127_7259849_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000167 147.0
GNS2_k127_7259849_5 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000597 109.0
GNS2_k127_7259849_6 - - - - 0.00000000000000000000008499 100.0
GNS2_k127_7259849_7 Cupredoxin-like domain - - - 0.000000000000001048 83.0
GNS2_k127_7259849_8 - - - - 0.000000000000893 72.0
GNS2_k127_7259849_9 Acetyltransferase (GNAT) domain - - - 0.0000005488 59.0
GNS2_k127_7283825_0 Carboxyl transferase domain - - - 3.946e-244 772.0
GNS2_k127_7283825_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 551.0
GNS2_k127_7283825_11 Helix-turn-helix XRE-family like proteins - - - 0.000001563 53.0
GNS2_k127_7283825_12 COG1910 Periplasmic molybdate-binding protein domain K07219 - - 0.0009642 46.0
GNS2_k127_7283825_2 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 551.0
GNS2_k127_7283825_3 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 428.0
GNS2_k127_7283825_4 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 406.0
GNS2_k127_7283825_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 339.0
GNS2_k127_7283825_6 DNA integration K14059 - - 0.000000000000000000000000000000000000000000000000000000000000000000006684 250.0
GNS2_k127_7283825_7 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000001152 206.0
GNS2_k127_7283825_8 - - - - 0.00000000000000002198 92.0
GNS2_k127_7283825_9 Helix-turn-helix domain - - - 0.000000004782 63.0
GNS2_k127_7301029_0 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 464.0
GNS2_k127_7301029_1 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002599 263.0
GNS2_k127_7301029_2 Starch synthase catalytic domain K16150 - 2.4.1.11 0.00000000000000000000000000000000000000000000000000000000005522 206.0
GNS2_k127_7301029_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.000000000000000000000000003891 115.0
GNS2_k127_7301029_4 Rv0623-like transcription factor K19687 - - 0.0000000000007626 74.0
GNS2_k127_7301029_5 Helix-turn-helix - - - 0.000002576 55.0
GNS2_k127_7326269_1 - - - - 0.0000000000000000000005365 108.0
GNS2_k127_7326269_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000871 75.0
GNS2_k127_7326269_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000004049 57.0
GNS2_k127_735931_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 305.0
GNS2_k127_735931_1 FES - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000154 249.0
GNS2_k127_735931_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000007795 226.0
GNS2_k127_735931_3 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000001184 178.0
GNS2_k127_735931_4 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000003624 170.0
GNS2_k127_735931_5 Cytochrome c - - - 0.00000002971 66.0
GNS2_k127_7389270_0 NADH flavin oxidoreductase NADH oxidase K00317 - 1.5.8.1,1.5.8.2 5.179e-229 728.0
GNS2_k127_7389270_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K21834 - - 9.37e-218 698.0
GNS2_k127_7389270_10 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000423 271.0
GNS2_k127_7389270_11 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000395 231.0
GNS2_k127_7389270_12 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000004774 222.0
GNS2_k127_7389270_13 Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000004694 234.0
GNS2_k127_7389270_14 Protein of unknown function (DUF861) K06995 - - 0.00000000000000000000000000000000000000000186 167.0
GNS2_k127_7389270_15 NUDIX domain - - - 0.00000000000000000000000000001505 121.0
GNS2_k127_7389270_16 Repressor involved in choline regulation of the bet genes K02167 - - 0.0000000000000009585 85.0
GNS2_k127_7389270_17 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000007322 73.0
GNS2_k127_7389270_2 CoA-transferase family III K14470 - 5.4.1.3 1.749e-206 648.0
GNS2_k127_7389270_3 Acyl dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 399.0
GNS2_k127_7389270_4 Belongs to the ABC transporter superfamily K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 371.0
GNS2_k127_7389270_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 359.0
GNS2_k127_7389270_6 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 342.0
GNS2_k127_7389270_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 327.0
GNS2_k127_7389270_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 304.0
GNS2_k127_7389270_9 Alcohol dehydrogenase GroES-like domain K18369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 297.0
GNS2_k127_7437440_0 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 546.0
GNS2_k127_7437440_1 Adenylate cyclase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 406.0
GNS2_k127_7437440_10 ammonium transporter K03320 - - 0.000000001292 61.0
GNS2_k127_7437440_11 universal stress protein - GO:0008150,GO:0040007 - 0.00003516 54.0
GNS2_k127_7437440_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 380.0
GNS2_k127_7437440_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002612 254.0
GNS2_k127_7437440_4 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000007854 181.0
GNS2_k127_7437440_5 - - - - 0.0000000000000000000000000000000000000001348 161.0
GNS2_k127_7437440_6 Phosphorylase superfamily K03784 - 2.4.2.1 0.0000000000000000000000000000000000000287 154.0
GNS2_k127_7437440_7 - - - - 0.000000000000000000000000005453 121.0
GNS2_k127_7437440_8 - - - - 0.00000000000000000002686 94.0
GNS2_k127_7466162_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 436.0
GNS2_k127_7466162_1 PFAM peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 384.0
GNS2_k127_7466162_10 Acetyltransferase (GNAT) domain K22479 - - 0.000000000000000000000000000000000000000000000001165 180.0
GNS2_k127_7466162_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000243 166.0
GNS2_k127_7466162_12 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000001412 130.0
GNS2_k127_7466162_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000007772 117.0
GNS2_k127_7466162_14 translation initiation factor activity K06996 - - 0.00000000000000000000000005738 117.0
GNS2_k127_7466162_15 Pyridine nucleotide-disulphide oxidoreductase K17218,K17229 - 1.8.2.3,1.8.5.4 0.0000000000000000000000006826 104.0
GNS2_k127_7466162_16 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000774 92.0
GNS2_k127_7466162_17 - - - - 0.00000000000001171 79.0
GNS2_k127_7466162_18 pathogenesis - - - 0.000008014 57.0
GNS2_k127_7466162_19 ATP GTP-binding protein - - - 0.0002243 51.0
GNS2_k127_7466162_2 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 334.0
GNS2_k127_7466162_20 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0007427 42.0
GNS2_k127_7466162_3 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 356.0
GNS2_k127_7466162_4 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 341.0
GNS2_k127_7466162_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 310.0
GNS2_k127_7466162_6 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001553 259.0
GNS2_k127_7466162_7 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000001469 224.0
GNS2_k127_7466162_8 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000002284 203.0
GNS2_k127_7466162_9 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000002691 216.0
GNS2_k127_7665735_0 AMP-binding enzyme C-terminal domain - - - 3.209e-204 649.0
GNS2_k127_7665735_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 504.0
GNS2_k127_7665735_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000005175 169.0
GNS2_k127_7665735_11 - - - - 0.000008774 49.0
GNS2_k127_7665735_2 sigma factor antagonist activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 476.0
GNS2_k127_7665735_3 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 371.0
GNS2_k127_7665735_4 Histidinol phosphate phosphatase, HisJ K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 367.0
GNS2_k127_7665735_5 Sigma-70 region 2 K03091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 341.0
GNS2_k127_7665735_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 301.0
GNS2_k127_7665735_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000529 228.0
GNS2_k127_7665735_8 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000007892 184.0
GNS2_k127_7665735_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000003584 171.0
GNS2_k127_7677032_0 peptidase S9 prolyl oligopeptidase active site domain protein - - - 5.892e-225 715.0
GNS2_k127_7677032_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.881e-208 700.0
GNS2_k127_7677032_10 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 310.0
GNS2_k127_7677032_11 protein histidine kinase activity K02484,K07640,K07643,K07645,K07649,K19609 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000201 295.0
GNS2_k127_7677032_12 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006479 282.0
GNS2_k127_7677032_13 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002217 282.0
GNS2_k127_7677032_14 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003313 274.0
GNS2_k127_7677032_15 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001979 281.0
GNS2_k127_7677032_16 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000001357 272.0
GNS2_k127_7677032_17 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000001486 232.0
GNS2_k127_7677032_18 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000000000000000001514 225.0
GNS2_k127_7677032_19 - - - - 0.00000000000000000000000000000000000000000000002649 177.0
GNS2_k127_7677032_2 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 500.0
GNS2_k127_7677032_20 AMP binding K16211 - - 0.00000000000000000000000000000000000000000008109 170.0
GNS2_k127_7677032_21 - - - - 0.000000000000000000000000000000000000006607 154.0
GNS2_k127_7677032_22 divalent heavy-metal cations transporter K07238 - - 0.000000000000000000000000000000009382 138.0
GNS2_k127_7677032_24 Belongs to the universal stress protein A family - - - 0.0000000000000005578 88.0
GNS2_k127_7677032_25 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.000000000001865 70.0
GNS2_k127_7677032_26 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0000004506 60.0
GNS2_k127_7677032_27 Aldo/keto reductase family - - - 0.000002066 54.0
GNS2_k127_7677032_28 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00007093 47.0
GNS2_k127_7677032_3 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 506.0
GNS2_k127_7677032_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 477.0
GNS2_k127_7677032_5 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 491.0
GNS2_k127_7677032_6 PFAM Glycosyl transferase, group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 428.0
GNS2_k127_7677032_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 347.0
GNS2_k127_7677032_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 361.0
GNS2_k127_7677032_9 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 326.0
GNS2_k127_7680672_0 ABC transporter K06158 - - 4.661e-231 731.0
GNS2_k127_7680672_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 407.0
GNS2_k127_7680672_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007521 246.0
GNS2_k127_7680672_3 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006264 230.0
GNS2_k127_7680672_4 Protein of unknown function (DUF1697) - - - 0.000000001941 68.0
GNS2_k127_7680672_5 competence protein ComEA helix-hairpin-helix repeat protein K02237 - - 0.00001507 49.0
GNS2_k127_7680672_6 PFAM cytochrome P450 - - - 0.0007442 43.0
GNS2_k127_7732932_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.0 1133.0
GNS2_k127_7732932_1 Amino acid permease - - - 7.68e-221 696.0
GNS2_k127_7732932_2 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 7.253e-212 667.0
GNS2_k127_7732932_3 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 481.0
GNS2_k127_7732932_4 peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 288.0
GNS2_k127_7732932_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001584 246.0
GNS2_k127_7732932_6 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000003002 164.0
GNS2_k127_7732932_8 bifunctional deaminase-reductase domain protein - - - 0.00000000002939 65.0
GNS2_k127_7872095_0 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 453.0
GNS2_k127_7872095_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 406.0
GNS2_k127_7872095_2 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 366.0
GNS2_k127_7872095_3 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 366.0
GNS2_k127_7872095_4 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 335.0
GNS2_k127_7872095_5 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 316.0
GNS2_k127_7872095_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000003701 186.0
GNS2_k127_7872095_7 competence protein - - - 0.00000000000000000000000000000000004225 142.0
GNS2_k127_7872095_8 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000005617 58.0
GNS2_k127_7912419_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 510.0
GNS2_k127_7912419_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 468.0
GNS2_k127_7912419_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 350.0
GNS2_k127_7912419_3 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000003574 176.0
GNS2_k127_7912419_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000009232 101.0
GNS2_k127_7912419_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000004013 86.0
GNS2_k127_7941955_0 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 464.0
GNS2_k127_7941955_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 469.0
GNS2_k127_7941955_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 292.0
GNS2_k127_7941955_3 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002636 252.0
GNS2_k127_7941955_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002096 248.0
GNS2_k127_7941955_5 transposase IS116 IS110 IS902 family - - - 0.000001607 55.0
GNS2_k127_7941955_6 protein conserved in bacteria - - - 0.00001802 53.0
GNS2_k127_79604_0 Participates in both transcription termination and antitermination K02600 - - 1.945e-198 632.0
GNS2_k127_79604_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 442.0
GNS2_k127_79604_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 355.0
GNS2_k127_79604_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000006059 216.0
GNS2_k127_79604_4 - - - - 0.000000000000000000000000000000000000004552 154.0
GNS2_k127_79604_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000002665 119.0
GNS2_k127_79604_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000003086 66.0
GNS2_k127_79604_7 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000007152 59.0
GNS2_k127_7976447_0 Inorganic H+ pyrophosphatase - - - 2.139e-260 821.0
GNS2_k127_7976447_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 437.0
GNS2_k127_7976447_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000002247 150.0
GNS2_k127_7976447_11 Glycoprotease family K14742 - - 0.00000000000000000000000000713 119.0
GNS2_k127_7976447_13 Glutaredoxin-like domain (DUF836) - - - 0.00000000000292 79.0
GNS2_k127_7976447_14 Putative regulatory protein - - - 0.000005996 56.0
GNS2_k127_7976447_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 386.0
GNS2_k127_7976447_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 377.0
GNS2_k127_7976447_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 355.0
GNS2_k127_7976447_5 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 314.0
GNS2_k127_7976447_6 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 266.0
GNS2_k127_7976447_7 Bacterial transferase hexapeptide (six repeats) K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000005854 233.0
GNS2_k127_7976447_8 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000006327 190.0
GNS2_k127_7976447_9 Aspartate decarboxylase K01579 - 4.1.1.11 0.000000000000000000000000000000000000001511 150.0
GNS2_k127_8039692_0 Alpha beta hydrolase K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 325.0
GNS2_k127_8039692_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004649 263.0
GNS2_k127_8039692_2 - - - - 0.00000000000000000000000000000000000000000000000218 189.0
GNS2_k127_8039692_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000001138 85.0
GNS2_k127_8039692_5 peptidase - - - 0.000000000006412 74.0
GNS2_k127_8039692_6 Staphylococcal nuclease homologue - - - 0.000000005052 59.0
GNS2_k127_8039692_7 Helix-turn-helix XRE-family like proteins - - - 0.000006428 56.0
GNS2_k127_8088013_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 586.0
GNS2_k127_8088013_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 470.0
GNS2_k127_8088013_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
GNS2_k127_8088013_3 peptidoglycan biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 351.0
GNS2_k127_8088013_4 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000009539 119.0
GNS2_k127_813155_0 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 2.253e-198 629.0
GNS2_k127_813155_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 586.0
GNS2_k127_813155_10 - - - - 0.0000000000000000000000000142 115.0
GNS2_k127_813155_11 Transcriptional regulator K14056 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000148 58.0
GNS2_k127_813155_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 531.0
GNS2_k127_813155_3 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 428.0
GNS2_k127_813155_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 410.0
GNS2_k127_813155_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 339.0
GNS2_k127_813155_6 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000189 257.0
GNS2_k127_813155_7 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000004758 227.0
GNS2_k127_813155_8 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000008189 184.0
GNS2_k127_813155_9 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000001938 175.0
GNS2_k127_8132840_0 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 529.0
GNS2_k127_8132840_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 487.0
GNS2_k127_8132840_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 481.0
GNS2_k127_8132840_3 COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 428.0
GNS2_k127_8132840_4 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 353.0
GNS2_k127_8240157_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 1.369e-195 638.0
GNS2_k127_8240157_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 497.0
GNS2_k127_8240157_2 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 419.0
GNS2_k127_8240157_3 Epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 339.0
GNS2_k127_8240157_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001171 284.0
GNS2_k127_8240157_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001118 257.0
GNS2_k127_8240157_6 - - - - 0.0000000000000000000000000000000000000000000000000000002055 205.0
GNS2_k127_8240157_7 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000001049 214.0
GNS2_k127_8241328_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 569.0
GNS2_k127_8241328_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001639 288.0
GNS2_k127_8241328_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000005413 266.0
GNS2_k127_8241328_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000009372 198.0
GNS2_k127_82665_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 8.14e-207 653.0
GNS2_k127_82665_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 521.0
GNS2_k127_82665_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003763 271.0
GNS2_k127_82665_3 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009989 273.0
GNS2_k127_82665_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000002704 253.0
GNS2_k127_82665_5 Receptor family ligand binding region K01999 - - 0.0002915 50.0
GNS2_k127_8276906_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 556.0
GNS2_k127_8276906_1 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 500.0
GNS2_k127_8276906_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000001138 78.0
GNS2_k127_8276906_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 466.0
GNS2_k127_8276906_3 helicase superfamily c-terminal domain K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 455.0
GNS2_k127_8276906_4 PFAM Iron permease FTR1 K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 355.0
GNS2_k127_8276906_5 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 299.0
GNS2_k127_8276906_6 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000003167 265.0
GNS2_k127_8276906_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009093 261.0
GNS2_k127_8276906_8 - - - - 0.0000000000000000000000000000000000000000000000000000000009735 213.0
GNS2_k127_8276906_9 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000000000001589 204.0
GNS2_k127_8349238_0 COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism K01652 - 2.2.1.6 4.09e-230 724.0
GNS2_k127_8349238_1 Ribonucleotide reductase, small chain K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 412.0
GNS2_k127_8349238_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000001597 71.0
GNS2_k127_8349238_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 366.0
GNS2_k127_8349238_3 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 346.0
GNS2_k127_8349238_4 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 319.0
GNS2_k127_8349238_5 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001531 266.0
GNS2_k127_8349238_6 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000000000000000000000000000000005606 177.0
GNS2_k127_8349238_7 Cold shock - - - 0.0000000000000000000000000000000000000001373 157.0
GNS2_k127_8349238_8 Rhomboid family - - - 0.0000000000000000000000000000000000000001404 164.0
GNS2_k127_8349238_9 - - - - 0.000000000000000002652 89.0
GNS2_k127_8421507_0 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 439.0
GNS2_k127_8421507_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 440.0
GNS2_k127_8421507_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 422.0
GNS2_k127_8421507_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003095 277.0
GNS2_k127_8421507_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000001971 216.0
GNS2_k127_8421507_5 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000001717 199.0
GNS2_k127_8421507_6 Lysyl oxidase - - - 0.000000000000000000000000000000000000000000000000004037 190.0
GNS2_k127_8421507_7 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000299 163.0
GNS2_k127_8421507_8 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000002494 120.0
GNS2_k127_8425483_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000003944 154.0
GNS2_k127_8425483_1 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000002059 140.0
GNS2_k127_8425483_2 methyltransferase K16648 - - 0.0000000000000000004669 98.0
GNS2_k127_8425483_3 PIN domain - - - 0.000000000000000001448 86.0
GNS2_k127_8425483_4 - - - - 0.00000000000000001715 84.0
GNS2_k127_8425483_5 DUF167 K09131 - - 0.00000000000000003925 92.0
GNS2_k127_8425483_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000937 60.0
GNS2_k127_8425483_7 Cupin domain - - - 0.000005543 54.0
GNS2_k127_8652688_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 446.0
GNS2_k127_8652688_1 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 387.0
GNS2_k127_8652688_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000009454 155.0
GNS2_k127_8652688_11 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000001248 139.0
GNS2_k127_8652688_12 Cytochrome C oxidase subunit II, transmembrane domain K02275 - 1.9.3.1 0.0000000000000000000000000000001246 132.0
GNS2_k127_8652688_13 amino acid transport K03294 - - 0.00000000000000000000000003033 115.0
GNS2_k127_8652688_14 Cytochrome c - - - 0.00000000000000003837 90.0
GNS2_k127_8652688_15 I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000001118 85.0
GNS2_k127_8652688_16 Transposase - - - 0.00001996 51.0
GNS2_k127_8652688_2 UbiA prenyltransferase family K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 362.0
GNS2_k127_8652688_3 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 308.0
GNS2_k127_8652688_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 312.0
GNS2_k127_8652688_5 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001365 273.0
GNS2_k127_8652688_6 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000926 271.0
GNS2_k127_8652688_7 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005298 276.0
GNS2_k127_8652688_8 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006541 273.0
GNS2_k127_8652688_9 - - - - 0.0000000000000000000000000000000000000000003307 167.0
GNS2_k127_8654323_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596 - 4.1.1.32 3.567e-318 982.0
GNS2_k127_8654323_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K15232 - 6.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 583.0
GNS2_k127_8654323_10 ATPase domain predominantly from Archaea - - - 0.000006764 51.0
GNS2_k127_8654323_2 HpcH/HpaI aldolase/citrate lyase family K08691 - 4.1.3.24,4.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 579.0
GNS2_k127_8654323_3 Succinyl-CoA ligase like flavodoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 485.0
GNS2_k127_8654323_4 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001908 301.0
GNS2_k127_8654323_5 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001091 254.0
GNS2_k127_8654323_6 6-phospho-beta-galactosidase activity - - - 0.0000000000000000000000000000009091 138.0
GNS2_k127_8654323_8 Cysteine-rich secretory protein family - - - 0.0000000000000231 80.0
GNS2_k127_8654323_9 peptidoglycan binding K02549 - 4.2.1.113 0.000002145 53.0
GNS2_k127_8670446_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1157.0
GNS2_k127_8670446_1 Protein of unknown function, DUF255 K06888 - - 1.27e-257 812.0
GNS2_k127_8670446_10 pfkB family carbohydrate kinase K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 294.0
GNS2_k127_8670446_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000104 283.0
GNS2_k127_8670446_12 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002185 280.0
GNS2_k127_8670446_13 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001099 269.0
GNS2_k127_8670446_14 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000418 251.0
GNS2_k127_8670446_15 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005926 241.0
GNS2_k127_8670446_16 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000001445 230.0
GNS2_k127_8670446_17 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000004584 187.0
GNS2_k127_8670446_18 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000009925 173.0
GNS2_k127_8670446_19 PIN domain - - - 0.00000000000000000000000000000000000000000003758 164.0
GNS2_k127_8670446_2 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 5.128e-215 693.0
GNS2_k127_8670446_20 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000001334 149.0
GNS2_k127_8670446_21 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000001395 137.0
GNS2_k127_8670446_22 translation release factor activity - - - 0.0000000000000000000000000000000008814 144.0
GNS2_k127_8670446_23 CcmE - - - 0.00000000000000000000000000000126 131.0
GNS2_k127_8670446_24 Belongs to the rubredoxin family - - - 0.0000000000000000000000007029 113.0
GNS2_k127_8670446_26 Lytic transglycolase - - - 0.00000000000000000000005491 105.0
GNS2_k127_8670446_27 - - - - 0.0000000000000000000001801 107.0
GNS2_k127_8670446_29 Preprotein translocase SecG subunit - - - 0.0000000000000000006826 102.0
GNS2_k127_8670446_3 Fatty acid desaturase K00496 - 1.14.15.3 2.111e-202 635.0
GNS2_k127_8670446_31 SEC-C Motif Domain Protein - - - 0.0000000000000005025 91.0
GNS2_k127_8670446_32 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000002597 83.0
GNS2_k127_8670446_33 sequence-specific DNA binding - - - 0.0000001254 63.0
GNS2_k127_8670446_34 Bacterial antitoxin of type II TA system, VapB - - - 0.00002869 48.0
GNS2_k127_8670446_4 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 594.0
GNS2_k127_8670446_5 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 567.0
GNS2_k127_8670446_6 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 544.0
GNS2_k127_8670446_7 Chitin synthase K11936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 393.0
GNS2_k127_8670446_8 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 372.0
GNS2_k127_8670446_9 LexA DNA binding domain K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 293.0
GNS2_k127_8680482_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.619e-301 937.0
GNS2_k127_8680482_1 Belongs to the GPI family K01810 - 5.3.1.9 3.664e-264 826.0
GNS2_k127_8680482_10 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 415.0
GNS2_k127_8680482_11 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 411.0
GNS2_k127_8680482_12 dUTP biosynthetic process K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 407.0
GNS2_k127_8680482_13 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 402.0
GNS2_k127_8680482_14 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 395.0
GNS2_k127_8680482_15 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 395.0
GNS2_k127_8680482_16 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 384.0
GNS2_k127_8680482_17 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 340.0
GNS2_k127_8680482_18 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 330.0
GNS2_k127_8680482_19 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 330.0
GNS2_k127_8680482_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 591.0
GNS2_k127_8680482_20 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 320.0
GNS2_k127_8680482_21 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 283.0
GNS2_k127_8680482_22 Belongs to the peptidase S8 family K14743 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001812 288.0
GNS2_k127_8680482_23 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000003882 259.0
GNS2_k127_8680482_25 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000009321 260.0
GNS2_k127_8680482_26 Nucleoside 2-deoxyribosyltransferase YtoQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000003588 232.0
GNS2_k127_8680482_27 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004894 239.0
GNS2_k127_8680482_28 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000002854 224.0
GNS2_k127_8680482_29 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000002936 195.0
GNS2_k127_8680482_3 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 557.0
GNS2_k127_8680482_30 - - - - 0.000000000000000000000000000000000000000000000000005025 184.0
GNS2_k127_8680482_31 PFAM UspA - - - 0.000000000000000000000000000000000000000000000004156 176.0
GNS2_k127_8680482_32 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000002611 162.0
GNS2_k127_8680482_33 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000007701 154.0
GNS2_k127_8680482_34 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000007253 144.0
GNS2_k127_8680482_35 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000918 154.0
GNS2_k127_8680482_36 RF-1 domain K15034 - - 0.0000000000000000000000000000000003445 140.0
GNS2_k127_8680482_37 MaoC like domain - - - 0.000000000000000000000000000001434 135.0
GNS2_k127_8680482_38 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000007217 130.0
GNS2_k127_8680482_39 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000000000248 119.0
GNS2_k127_8680482_4 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 529.0
GNS2_k127_8680482_40 - - - - 0.000000000000000000000002744 111.0
GNS2_k127_8680482_41 Transcriptional regulator - - - 0.0000000000000000000001472 107.0
GNS2_k127_8680482_42 dehydratase K01724 - 4.2.1.96 0.00000000000000000007355 102.0
GNS2_k127_8680482_43 Phosphopantetheine attachment site K02078 - - 0.00000000000000001879 85.0
GNS2_k127_8680482_44 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000207 97.0
GNS2_k127_8680482_45 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - 0.00000000000001195 87.0
GNS2_k127_8680482_47 - - - - 0.0000000007026 70.0
GNS2_k127_8680482_48 - - - - 0.000001833 53.0
GNS2_k127_8680482_5 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 539.0
GNS2_k127_8680482_6 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 475.0
GNS2_k127_8680482_7 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 445.0
GNS2_k127_8680482_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 451.0
GNS2_k127_8680482_9 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 442.0
GNS2_k127_8687988_0 E1-E2 ATPase K01547 - 3.6.3.12 0.0 1044.0
GNS2_k127_8687988_1 Potassium-transporting ATPase A subunit K01546 - 3.6.3.12 2.007e-222 705.0
GNS2_k127_8687988_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 551.0
GNS2_k127_8687988_3 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 353.0
GNS2_k127_8687988_4 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 338.0
GNS2_k127_8687988_5 - - - - 0.0000003397 57.0
GNS2_k127_8739896_0 Alanine racemase, N-terminal domain K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000364 248.0
GNS2_k127_8739896_1 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.000000000000000000000000000000000000000000000000000000000000000003705 230.0
GNS2_k127_8739896_2 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000000000000000000000000000000000000002186 216.0
GNS2_k127_8739896_3 Poly A polymerase head domain - - - 0.0000000000000000000000000000000000000000000000000000007101 205.0
GNS2_k127_8739896_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000001895 63.0
GNS2_k127_8783734_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.795e-216 680.0
GNS2_k127_8783734_1 COG COG0531 Amino acid transporters Amino acid transport and metabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 513.0
GNS2_k127_8783734_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 476.0
GNS2_k127_8783734_3 Purine catabolism regulatory protein-like family K09684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 354.0
GNS2_k127_8783734_4 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 329.0
GNS2_k127_8783734_5 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 296.0
GNS2_k127_8783734_6 Binding-protein-dependent transport system inner membrane component K02053,K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004187 265.0
GNS2_k127_8783734_7 Universal stress protein family - - - 0.00000000000000000000000000002408 135.0
GNS2_k127_8783734_8 Aldehyde dehydrogenase family K22187 - - 0.0009133 46.0
GNS2_k127_8805832_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 511.0
GNS2_k127_8805832_1 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003388 272.0
GNS2_k127_8805832_2 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007133 271.0
GNS2_k127_8805832_3 Elongator protein 3 MiaB NifB K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000006022 194.0
GNS2_k127_8805832_4 FeoA K03709 - - 0.0000000000000000000000000000000000000000001504 177.0
GNS2_k127_8805832_5 - - - - 0.0000000000000000000000000000000000000006341 152.0
GNS2_k127_8805832_6 Belongs to the MIP aquaporin (TC 1.A.8) family K02440,K06188,K09874 - - 0.000000000000000000000000000000000000001275 157.0
GNS2_k127_8805832_7 - - - - 0.000000007641 63.0
GNS2_k127_8853804_0 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 516.0
GNS2_k127_8853804_1 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 443.0
GNS2_k127_8853804_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 355.0
GNS2_k127_8853804_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000675 196.0
GNS2_k127_8853804_4 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000608 162.0
GNS2_k127_8853804_6 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000002894 96.0
GNS2_k127_8853804_7 - - - - 0.000008146 58.0
GNS2_k127_8870914_0 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 470.0
GNS2_k127_8870914_1 Domain of unknown function (DUF4430) - - - 0.000000000000000000000000000000000000000000000000000000000000003976 227.0
GNS2_k127_8870914_2 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000001752 139.0
GNS2_k127_8870914_3 Tetratricopeptide repeat - - - 0.0000000000000000000000009893 107.0
GNS2_k127_8870914_4 Cobalt transport protein K16785 - - 0.000000000000000000006142 107.0
GNS2_k127_8870914_5 Acetyltransferase (GNAT) domain - - - 0.0000001937 58.0
GNS2_k127_8870914_6 - - - - 0.00007605 53.0
GNS2_k127_8870914_7 regulation of DNA-templated transcription, elongation - - - 0.0005318 53.0
GNS2_k127_8884878_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 444.0
GNS2_k127_8884878_1 COG0402 Cytosine deaminase and related metal-dependent hydrolases K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 369.0
GNS2_k127_8884878_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001862 263.0
GNS2_k127_8884878_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K19696 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28,2.4.2.44 0.0000000000000000000000000000000000000000000000005247 183.0
GNS2_k127_8884878_4 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) K01083,K01113,K01126 - 3.1.3.1,3.1.3.8,3.1.4.46 0.00000000000000000000000000000002091 141.0
GNS2_k127_8884878_5 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000215 128.0
GNS2_k127_8884878_6 PAS domain - - - 0.000000000000000000000003655 108.0
GNS2_k127_8884878_7 Region found in RelA / SpoT proteins K00951 - 2.7.6.5 0.00000000000000001251 93.0
GNS2_k127_8886326_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1161.0
GNS2_k127_8886326_1 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000001148 194.0
GNS2_k127_8886326_2 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000000000000000000000002395 163.0
GNS2_k127_8886326_3 - - - - 0.00000000000000000000001989 102.0
GNS2_k127_8887446_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.739e-313 975.0
GNS2_k127_8887446_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.173e-245 772.0
GNS2_k127_8887446_10 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000005436 160.0
GNS2_k127_8887446_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000008944 120.0
GNS2_k127_8887446_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000008909 126.0
GNS2_k127_8887446_2 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 469.0
GNS2_k127_8887446_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 392.0
GNS2_k127_8887446_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 370.0
GNS2_k127_8887446_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 327.0
GNS2_k127_8887446_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002721 278.0
GNS2_k127_8887446_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000006189 255.0
GNS2_k127_8887446_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000002872 216.0
GNS2_k127_8887446_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000001138 165.0
GNS2_k127_8897026_0 dipeptidyl-peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 466.0
GNS2_k127_8897026_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000005662 243.0
GNS2_k127_8897026_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000000002932 215.0
GNS2_k127_8897026_3 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000002126 196.0
GNS2_k127_8897026_4 helicase superfamily c-terminal domain K03654 - 3.6.4.12 0.00000000000000000000000000000001854 133.0
GNS2_k127_8897026_5 Belongs to the glycosyl hydrolase 26 family K01179 GO:0003674,GO:0003824,GO:0004553,GO:0008810,GO:0016787,GO:0016798 3.2.1.4 0.00000001181 69.0
GNS2_k127_8897026_6 Belongs to the glycosyl hydrolase 26 family - - - 0.00000006571 64.0
GNS2_k127_8938566_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.205e-310 972.0
GNS2_k127_8938566_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 554.0
GNS2_k127_8938566_2 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.0000000000000000000000000000000000000000693 168.0
GNS2_k127_8938566_3 Septum formation initiator - - - 0.0000000000005699 74.0
GNS2_k127_8967988_0 DEAD-like helicases superfamily K03724,K06877 - - 0.0 1493.0
GNS2_k127_8967988_1 PFAM MMPL domain protein K06994 - - 1.589e-203 659.0
GNS2_k127_8976581_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 2.397e-195 625.0
GNS2_k127_8976581_1 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 614.0
GNS2_k127_8976581_10 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000007597 190.0
GNS2_k127_8976581_11 DNA-binding transcription factor activity K03710 - - 0.00000000000000000000000000000000000000000000000003205 196.0
GNS2_k127_8976581_12 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000007101 179.0
GNS2_k127_8976581_13 FxsA cytoplasmic membrane protein - - - 0.0000000000000000000000000000000000002507 146.0
GNS2_k127_8976581_14 - - - - 0.00000000000000000000000006561 111.0
GNS2_k127_8976581_2 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 514.0
GNS2_k127_8976581_3 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 453.0
GNS2_k127_8976581_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 453.0
GNS2_k127_8976581_5 Uncharacterized protein family (UPF0051) K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 417.0
GNS2_k127_8976581_6 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 383.0
GNS2_k127_8976581_7 Dehydrogenase K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 375.0
GNS2_k127_8976581_8 Belongs to the HAD-like hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 304.0
GNS2_k127_8976581_9 2-Nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000125 265.0
GNS2_k127_8979355_0 Ribonuclease E/G family K08301 - - 5.218e-243 764.0
GNS2_k127_8979355_1 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 549.0
GNS2_k127_8979355_10 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - 0.0000000000000000000003572 110.0
GNS2_k127_8979355_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 479.0
GNS2_k127_8979355_3 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 387.0
GNS2_k127_8979355_4 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 321.0
GNS2_k127_8979355_5 rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000004003 229.0
GNS2_k127_8979355_6 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000000000000000009016 207.0
GNS2_k127_8979355_7 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000158 198.0
GNS2_k127_8979355_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000003548 194.0
GNS2_k127_8979355_9 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000008919 159.0
GNS2_k127_9000442_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1839.0
GNS2_k127_9000442_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 6.692e-215 673.0
GNS2_k127_9000442_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 327.0
GNS2_k127_9000442_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 292.0
GNS2_k127_9000442_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000006097 226.0
GNS2_k127_9000442_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000001922 194.0
GNS2_k127_9000442_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000004299 173.0
GNS2_k127_9000442_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000007732 105.0
GNS2_k127_9000442_8 SecE/Sec61-gamma subunits of protein translocation complex - - - 0.0000007266 57.0
GNS2_k127_9044221_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.167e-282 896.0
GNS2_k127_9044221_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.097e-229 719.0
GNS2_k127_9044221_10 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 323.0
GNS2_k127_9044221_11 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001991 286.0
GNS2_k127_9044221_12 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000213 261.0
GNS2_k127_9044221_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000009966 201.0
GNS2_k127_9044221_14 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000459 191.0
GNS2_k127_9044221_15 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000006632 159.0
GNS2_k127_9044221_16 PIN domain - - - 0.0000000000000000000000000000000000003242 149.0
GNS2_k127_9044221_17 - - - - 0.0000000000000000000000000001056 131.0
GNS2_k127_9044221_18 GYD domain - - - 0.000000000000000000000000001933 117.0
GNS2_k127_9044221_19 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.00000000000000000000002534 111.0
GNS2_k127_9044221_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.552e-199 633.0
GNS2_k127_9044221_21 Antitoxin component of a toxin-antitoxin (TA) module - GO:0003674,GO:0005488,GO:0008150,GO:0015643,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00000000000000000004994 92.0
GNS2_k127_9044221_22 - - - - 0.000000000000000001488 98.0
GNS2_k127_9044221_23 Transposase - - - 0.00000000000005145 80.0
GNS2_k127_9044221_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 549.0
GNS2_k127_9044221_4 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 481.0
GNS2_k127_9044221_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 429.0
GNS2_k127_9044221_6 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 394.0
GNS2_k127_9044221_7 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 374.0
GNS2_k127_9044221_8 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 348.0
GNS2_k127_9044221_9 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 350.0
GNS2_k127_9051472_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 3.051e-202 665.0
GNS2_k127_9051472_1 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 567.0
GNS2_k127_9051472_10 - - - - 0.000000000000000000000199 103.0
GNS2_k127_9051472_11 BolA-like protein - - - 0.000000000000009321 76.0
GNS2_k127_9051472_12 - - - - 0.0000000001101 64.0
GNS2_k127_9051472_13 - - - - 0.0000000003225 70.0
GNS2_k127_9051472_14 helix_turn_helix, mercury resistance - - - 0.00000009584 54.0
GNS2_k127_9051472_2 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 336.0
GNS2_k127_9051472_3 TIGRFAM degV family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 328.0
GNS2_k127_9051472_4 Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005053 274.0
GNS2_k127_9051472_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 268.0
GNS2_k127_9051472_6 YsiA-like protein, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 267.0
GNS2_k127_9051472_7 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000003306 136.0
GNS2_k127_9051472_8 Glutaredoxin K07390 - - 0.0000000000000000000000000000005215 128.0
GNS2_k127_9051472_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000000000003313 118.0
GNS2_k127_9100245_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 503.0
GNS2_k127_9100245_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 473.0
GNS2_k127_9100245_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 334.0
GNS2_k127_9100245_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 319.0
GNS2_k127_9100245_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002334 249.0
GNS2_k127_9100245_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000005055 192.0
GNS2_k127_9100245_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000005553 152.0
GNS2_k127_9100245_7 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000268 134.0
GNS2_k127_9100245_8 - - - - 0.0000000000007641 74.0
GNS2_k127_9100245_9 sequence-specific DNA binding - - - 0.000001973 53.0
GNS2_k127_9160574_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.984e-261 818.0
GNS2_k127_9160574_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000008455 182.0
GNS2_k127_9160574_2 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000000000000000000001812 189.0
GNS2_k127_9160574_3 SnoaL-like polyketide cyclase K06893 - - 0.000000000000002305 81.0
GNS2_k127_918528_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 580.0
GNS2_k127_918528_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 450.0
GNS2_k127_918528_10 ATP synthase subunit C K02110 - - 0.0000000000000000000000000005751 115.0
GNS2_k127_918528_11 - - - - 0.0000000000005784 74.0
GNS2_k127_918528_2 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 407.0
GNS2_k127_918528_3 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 338.0
GNS2_k127_918528_4 ATP synthase A chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 335.0
GNS2_k127_918528_5 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 320.0
GNS2_k127_918528_6 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000001677 245.0
GNS2_k127_918528_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000003398 216.0
GNS2_k127_918528_8 ATP synthase B/B' CF(0) K02109 - - 0.0000000000000000000000000000000000000000000000000208 185.0
GNS2_k127_918528_9 SMART metal-dependent phosphohydrolase, HD K06885 - - 0.0000000000000000000000000000000000000000004553 182.0
GNS2_k127_9211209_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 7.45e-220 694.0
GNS2_k127_9211209_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 455.0
GNS2_k127_9211209_2 Belongs to the DegT DnrJ EryC1 family K12452,K13010 - 1.17.1.1,2.6.1.102 0.000000000000000000000000000000000000000000000000000000000002169 224.0
GNS2_k127_9223523_0 Dak1_2 K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 606.0
GNS2_k127_9223523_1 Drug exporters of the RND superfamily K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 613.0
GNS2_k127_9223523_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 596.0
GNS2_k127_9223523_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005976 248.0
GNS2_k127_9223523_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000003507 219.0
GNS2_k127_9223523_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000001392 213.0
GNS2_k127_9223523_6 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000274 176.0
GNS2_k127_9223523_7 RNA methyltransferase RsmD family K08316 - 2.1.1.171 0.0000000000000000000000000000000000004552 147.0
GNS2_k127_9223523_8 methyltransferase - - - 0.0000000000000000000000002647 118.0
GNS2_k127_9223523_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000005291 85.0
GNS2_k127_9313002_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 608.0
GNS2_k127_9313002_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 550.0
GNS2_k127_9313002_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 300.0
GNS2_k127_9313002_3 lipopolysaccharide transmembrane transporter activity K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001538 284.0
GNS2_k127_9313002_4 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000005993 240.0
GNS2_k127_9313002_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000003605 149.0
GNS2_k127_9313002_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000006702 97.0
GNS2_k127_9369213_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 316.0
GNS2_k127_9369213_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000003 251.0
GNS2_k127_9369213_2 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002186 248.0
GNS2_k127_9369213_3 methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000002771 243.0
GNS2_k127_9369213_4 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000002572 222.0
GNS2_k127_9369213_5 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000004592 175.0
GNS2_k127_9371740_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 430.0
GNS2_k127_9371740_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 416.0
GNS2_k127_9371740_10 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000002585 131.0
GNS2_k127_9371740_11 chlorophyll binding - - - 0.000000000005006 76.0
GNS2_k127_9371740_13 - - - - 0.000002001 60.0
GNS2_k127_9371740_14 general secretion pathway protein - - - 0.000009363 58.0
GNS2_k127_9371740_15 - - - - 0.0001077 51.0
GNS2_k127_9371740_2 pilus assembly protein PilW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008744 298.0
GNS2_k127_9371740_3 Anion-transporting ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001345 265.0
GNS2_k127_9371740_4 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000007948 247.0
GNS2_k127_9371740_5 Type IV leader peptidase family K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000002892 216.0
GNS2_k127_9371740_6 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000006528 175.0
GNS2_k127_9371740_7 - - - - 0.0000000000000000000000000000000000000000000003479 186.0
GNS2_k127_9371740_8 PFAM Fimbrial assembly family protein - - - 0.0000000000000000000000000000000000000003605 158.0
GNS2_k127_9371740_9 - - - - 0.00000000000000000000000000000000269 145.0
GNS2_k127_9570080_0 C-terminal domain of alpha-glycerophosphate oxidase - - - 2.092e-201 643.0
GNS2_k127_9570080_1 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 432.0
GNS2_k127_9570080_10 Nitroreductase family - - - 0.0000000000000000000000000000000000000000001386 183.0
GNS2_k127_9570080_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000001456 169.0
GNS2_k127_9570080_12 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000000000000000000000005635 161.0
GNS2_k127_9570080_13 SMART peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000000000000000000000333 158.0
GNS2_k127_9570080_14 Beta-lactamase - - - 0.00000000000000000000000000000000000187 151.0
GNS2_k127_9570080_15 PIN domain - - - 0.00000000000000000003218 94.0
GNS2_k127_9570080_16 pathogenesis K01390,K08643,K21471,K21687 GO:0005575,GO:0005618,GO:0005623,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.24.13 0.0000000000000002083 87.0
GNS2_k127_9570080_17 Lamin Tail Domain - - - 0.000000000000001889 83.0
GNS2_k127_9570080_18 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000004533 79.0
GNS2_k127_9570080_19 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000005623 68.0
GNS2_k127_9570080_2 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 426.0
GNS2_k127_9570080_20 toxin-antitoxin pair type II binding - - - 0.00000002064 57.0
GNS2_k127_9570080_21 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000004869 64.0
GNS2_k127_9570080_22 serine threonine protein kinase - - - 0.0000002232 60.0
GNS2_k127_9570080_23 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000004885 62.0
GNS2_k127_9570080_24 Zinc finger, swim domain protein - - - 0.0001499 45.0
GNS2_k127_9570080_3 Psort location CytoplasmicMembrane, score K16927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 403.0
GNS2_k127_9570080_4 PFAM ABC transporter related K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004357 267.0
GNS2_k127_9570080_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007018 250.0
GNS2_k127_9570080_6 pfkB family carbohydrate kinase K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000002588 243.0
GNS2_k127_9570080_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004985 224.0
GNS2_k127_9570080_8 ATPase (AAA superfamily) K06921 - - 0.000000000000000000000000000000000000000000000000000000000000001883 244.0
GNS2_k127_9570080_9 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000003776 213.0
GNS2_k127_9576536_0 ATP-dependent DNA helicase K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 364.0
GNS2_k127_9576536_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 331.0
GNS2_k127_9626741_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.206e-195 636.0
GNS2_k127_9626741_1 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 384.0
GNS2_k127_9626741_10 Domain of unknown function (DUF4189) - - - 0.00001164 54.0
GNS2_k127_9626741_2 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 368.0
GNS2_k127_9626741_3 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000001911 184.0
GNS2_k127_9626741_4 YceI-like domain - - - 0.000000000000000000000000000000000000000000004745 169.0
GNS2_k127_9626741_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000001971 177.0
GNS2_k127_9626741_6 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000005602 154.0
GNS2_k127_9626741_7 MarR family - - - 0.00000000000000000002574 97.0
GNS2_k127_9626741_8 TIGRFAM channel protein, hemolysin III family K11068 - - 0.00000000000000002526 82.0
GNS2_k127_9626741_9 toxin-antitoxin pair type II binding - - - 0.00000000000000006401 85.0
GNS2_k127_9655416_0 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 4.252e-312 967.0
GNS2_k127_9655416_1 Carboxyl transferase domain - - - 3.258e-216 683.0
GNS2_k127_9655416_10 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000006969 85.0
GNS2_k127_9655416_2 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 440.0
GNS2_k127_9655416_3 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006033 279.0
GNS2_k127_9655416_4 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000298 196.0
GNS2_k127_9655416_5 DNA mismatch endonuclease Vsr K07458 - - 0.0000000000000000000000000000000000000000000007585 170.0
GNS2_k127_9655416_6 TIR domain - - - 0.000000000000000000000000000000000002756 154.0
GNS2_k127_9655416_7 PFAM C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000000000000000000000000003651 124.0
GNS2_k127_9655416_9 Acid phosphatase homologues - - - 0.00000000000000000000003284 108.0
GNS2_k127_987675_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 382.0
GNS2_k127_987675_1 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 362.0
GNS2_k127_987675_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 336.0
GNS2_k127_987675_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000001424 155.0
GNS2_k127_987675_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000001507 147.0
GNS2_k127_987675_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000034 128.0
GNS2_k127_987675_6 Psort location Cytoplasmic, score K02479,K07692 - - 0.000000000000000000361 95.0
GNS2_k127_987675_7 Band 7 protein - - - 0.0004763 51.0