Overview

ID MAG01526
Name GZD1_bin.70
Sample SMP0040
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Nitrososphaeria
Order Nitrososphaerales
Family UBA183
Genus BOG-1369
Species
Assembly information
Completeness (%) 81.51
Contamination (%) 0.55
GC content (%) 61.0
N50 (bp) 12,980
Genome size (bp) 1,594,431

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1398

Gene name Description KEGG GOs EC E-value Score Sequence
GZD1_k127_1096738_0 DEAD DEAH box helicase domain protein K03724 - - 5.98e-234 756.0
GZD1_k127_1096738_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 414.0
GZD1_k127_1096738_2 ICC-like phosphoesterases K06953 - - 0.0000000000000000000000000000000000000005002 158.0
GZD1_k127_1096738_3 - - - - 0.00000000000000000000000000000005824 133.0
GZD1_k127_1096738_4 Thioredoxin K03671 - - 0.0000000000000000000000000002817 119.0
GZD1_k127_1096738_5 NUDIX domain - - - 0.000000000000000000000000001809 120.0
GZD1_k127_1096738_6 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.000000000000000000000003895 119.0
GZD1_k127_1096738_7 structural maintenance of - GO:0000166,GO:0000725,GO:0000793,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007059,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022402,GO:0030554,GO:0030915,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051304,GO:0051716,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0106068,GO:1901265,GO:1901360,GO:1901363,GO:1902494,GO:1990234 - 0.0000000000000002557 93.0
GZD1_k127_1096738_8 Structural maintenance of chromosomes protein - - - 0.00000000000002185 87.0
GZD1_k127_1122652_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1618.0
GZD1_k127_1122652_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000003964 93.0
GZD1_k127_1168126_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 434.0
GZD1_k127_1168126_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000004927 168.0
GZD1_k127_1168126_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000007968 160.0
GZD1_k127_1168126_3 ribosomal protein K02976 - - 0.0000000000000000000000000000004402 124.0
GZD1_k127_1168126_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000004275 121.0
GZD1_k127_1168126_5 - - - - 0.00000000000000001406 84.0
GZD1_k127_1168126_6 transcriptional regulators - - - 0.0000003481 59.0
GZD1_k127_1168126_7 DNA polymerase K02319 - 2.7.7.7 0.000158 44.0
GZD1_k127_1256523_0 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 397.0
GZD1_k127_1256523_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000003518 195.0
GZD1_k127_1256523_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000001246 183.0
GZD1_k127_1256523_3 transcriptional - - - 0.00000000000000006549 89.0
GZD1_k127_1256523_4 transporter K07238 - - 0.00000004006 64.0
GZD1_k127_1256523_5 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.000001011 57.0
GZD1_k127_126190_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 422.0
GZD1_k127_126190_1 Belongs to the FPP GGPP synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004634 241.0
GZD1_k127_126190_10 COG3316 Transposase and inactivated derivatives K07498 - - 0.00000000000706 73.0
GZD1_k127_126190_11 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000003556 57.0
GZD1_k127_126190_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000001196 229.0
GZD1_k127_126190_3 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000003131 161.0
GZD1_k127_126190_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000001211 160.0
GZD1_k127_126190_5 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000001342 168.0
GZD1_k127_126190_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000003712 117.0
GZD1_k127_126190_7 Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K06981 - 2.7.4.26 0.000000000000000000000000001474 128.0
GZD1_k127_126190_8 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000004976 106.0
GZD1_k127_126190_9 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000003683 70.0
GZD1_k127_1264716_0 GTPase of unknown function C-terminal K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 550.0
GZD1_k127_1264716_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02298,K15408 - 1.10.3.10,1.9.3.1 0.0000000002203 61.0
GZD1_k127_1264716_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000001268 55.0
GZD1_k127_1268889_0 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 376.0
GZD1_k127_1268889_1 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.00000000000000000000000000000000000000253 163.0
GZD1_k127_1268889_2 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000001226 151.0
GZD1_k127_1268889_3 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000001317 90.0
GZD1_k127_1268889_4 - - - - 0.00000000000000001751 96.0
GZD1_k127_1268889_5 thymidylate kinase K00943 - 2.7.4.9 0.000000000000001448 88.0
GZD1_k127_1268889_6 Glycosyl transferase 4-like - - - 0.000000000000005924 89.0
GZD1_k127_1268889_7 Peptidase A24A, prepilin type IV K02278,K07991 - 3.4.23.43,3.4.23.52 0.0000002796 60.0
GZD1_k127_1268889_8 Glycosyl transferases group 1 - - - 0.000007373 57.0
GZD1_k127_1302081_0 Heat shock 70 kDa protein K04043 - - 1.807e-232 742.0
GZD1_k127_1302081_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 359.0
GZD1_k127_1302081_2 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001952 217.0
GZD1_k127_1302081_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000002213 124.0
GZD1_k127_1302081_4 K homology RNA-binding domain K06961 - - 0.0000000000000000000000009378 116.0
GZD1_k127_1302081_5 Translation initiation factor K03238 - - 0.00000000000000000000008727 99.0
GZD1_k127_1302081_6 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000001158 98.0
GZD1_k127_1394104_0 Radical SAM K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000001903 238.0
GZD1_k127_1394104_1 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000000000000000000000000000000002545 212.0
GZD1_k127_1394104_2 Domain of unknown function (DUF309) K09763 - - 0.00000000000000000005974 97.0
GZD1_k127_1394104_3 - - - - 0.000000000000002946 84.0
GZD1_k127_1394104_4 Protein of unknown function DUF47 K07220 - - 0.000000000000117 79.0
GZD1_k127_1394104_5 Phosphate transporter family K03306 - - 0.000000001408 69.0
GZD1_k127_1394104_6 Winged helix-turn-helix - - - 0.00000009774 59.0
GZD1_k127_1394104_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00008898 53.0
GZD1_k127_1422152_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 510.0
GZD1_k127_1422152_1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 475.0
GZD1_k127_1422152_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 344.0
GZD1_k127_1422152_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000003687 208.0
GZD1_k127_1422152_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000005165 98.0
GZD1_k127_1422152_5 Translation initiation factor K03238 - - 0.00000000000000008629 85.0
GZD1_k127_1422152_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000008414 76.0
GZD1_k127_142978_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 245.0
GZD1_k127_142978_1 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000004275 230.0
GZD1_k127_142978_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000151 181.0
GZD1_k127_142978_3 SnoaL-like domain - - - 0.000000000000000000000000003339 116.0
GZD1_k127_142978_4 Glyoxalase-like domain K06996 - - 0.0000000000000000000003485 100.0
GZD1_k127_142978_5 Belongs to the SUI1 family K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000005439 93.0
GZD1_k127_142978_6 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000001887 99.0
GZD1_k127_142978_7 PFAM Glutamine amidotransferase class-I - - - 0.000000000000000004156 94.0
GZD1_k127_142978_8 Methyltransferase domain - - - 0.000000000002179 76.0
GZD1_k127_142978_9 Protein of unknown function (DUF1634) - - - 0.00001403 57.0
GZD1_k127_1430130_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000007853 265.0
GZD1_k127_1430130_1 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000001699 189.0
GZD1_k127_1430130_2 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000001516 179.0
GZD1_k127_1430130_3 Ferrous iron uptake permease, iron-lead transporter - - - 0.00000006349 57.0
GZD1_k127_1491718_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 7.785e-216 692.0
GZD1_k127_1491718_1 Thermopsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005443 306.0
GZD1_k127_1491718_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000004952 189.0
GZD1_k127_1491718_3 aminopeptidase K19689 - - 0.000002155 59.0
GZD1_k127_157950_0 component I K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 469.0
GZD1_k127_157950_1 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000005448 256.0
GZD1_k127_157950_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000006077 174.0
GZD1_k127_157950_3 - - - - 0.000000000000000000002215 101.0
GZD1_k127_160426_0 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000001453 218.0
GZD1_k127_160426_1 PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000374 191.0
GZD1_k127_160426_2 4-vinyl reductase, 4VR K06382,K07013 - 3.1.3.16 0.0009065 44.0
GZD1_k127_1674879_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 559.0
GZD1_k127_1674879_1 COG0433 Predicted ATPase K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 468.0
GZD1_k127_1674879_4 PFAM NurA domain - - - 0.00000000000000000000000000000002378 139.0
GZD1_k127_1675537_0 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003943 271.0
GZD1_k127_1675537_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006965 261.0
GZD1_k127_1675537_11 SdpI/YhfL protein family - - - 0.00000000007411 66.0
GZD1_k127_1675537_12 CopG domain protein DNA-binding domain protein - - - 0.00000000009389 66.0
GZD1_k127_1675537_13 membrane protein (DUF2078) K08982 - - 0.0000000008182 64.0
GZD1_k127_1675537_14 Domain of unknown function (DUF3368) K07066 - - 0.000001099 55.0
GZD1_k127_1675537_15 Short C-terminal domain K08982 - - 0.000003876 52.0
GZD1_k127_1675537_3 - - - - 0.0000000000000000000000000000000000000005824 167.0
GZD1_k127_1675537_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000002007 142.0
GZD1_k127_1675537_5 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000005215 106.0
GZD1_k127_1675537_6 Protein of unknown function (DUF998) - - - 0.0000000000000002185 91.0
GZD1_k127_1675537_7 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000005467 81.0
GZD1_k127_1675537_8 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000002615 83.0
GZD1_k127_1675537_9 Multicopper oxidase - - - 0.0000000000001163 77.0
GZD1_k127_1689710_0 Tubulin like - - - 0.000000000000000000000000006332 129.0
GZD1_k127_1689710_1 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000008758 100.0
GZD1_k127_1689710_2 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0001216 51.0
GZD1_k127_1720343_0 Zn-dependent protease with chaperone function K03799 - - 0.00000000000000000000000000000000000000000000000000000622 211.0
GZD1_k127_1720343_1 - - - - 0.0000000002202 69.0
GZD1_k127_1775169_0 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 497.0
GZD1_k127_1775169_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 461.0
GZD1_k127_1775169_10 ABC-type metal ion transport system periplasmic component surface adhesin K09815,K11707 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 319.0
GZD1_k127_1775169_11 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 305.0
GZD1_k127_1775169_12 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001712 275.0
GZD1_k127_1775169_13 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002563 277.0
GZD1_k127_1775169_14 diphthine synthase K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000005334 245.0
GZD1_k127_1775169_15 tRNA pseudouridine synthase K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000001229 233.0
GZD1_k127_1775169_16 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.0000000000000000000000000000000000000000000000000000000001876 209.0
GZD1_k127_1775169_17 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000009479 204.0
GZD1_k127_1775169_18 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000004421 196.0
GZD1_k127_1775169_19 ribosomal protein K02956 - - 0.000000000000000000000000000000000000000000000000001627 186.0
GZD1_k127_1775169_2 GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 399.0
GZD1_k127_1775169_20 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000003344 187.0
GZD1_k127_1775169_21 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001087 190.0
GZD1_k127_1775169_22 Ribosomal protein L15E K02877 - - 0.00000000000000000000000000000000000000000002803 166.0
GZD1_k127_1775169_23 Translin family K07477 - - 0.0000000000000000000000000000000000000000002056 167.0
GZD1_k127_1775169_24 Mn2 -dependent serine threonine protein kinase K08851 - 2.7.11.1 0.000000000000000000000000000000000000000000242 168.0
GZD1_k127_1775169_25 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000855 160.0
GZD1_k127_1775169_26 Peptidyl-tRNA hydrolase PTH2 K04794 - 3.1.1.29 0.000000000000000000000000000000000000259 143.0
GZD1_k127_1775169_27 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.00000000000000000000000000000000001143 139.0
GZD1_k127_1775169_28 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000008868 134.0
GZD1_k127_1775169_29 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.0000000000000000000000000000005324 130.0
GZD1_k127_1775169_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 396.0
GZD1_k127_1775169_30 Transcriptional regulator K07722 - - 0.00000000000000000000000000002373 121.0
GZD1_k127_1775169_31 Pfam:DUF552 K09152 - - 0.0000000000000000000000000003684 117.0
GZD1_k127_1775169_32 snRNP Sm proteins K04796 - - 0.0000000000000000000000000005079 119.0
GZD1_k127_1775169_33 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000001229 116.0
GZD1_k127_1775169_34 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K03885,K18367 - 1.6.99.3,1.8.1.18 0.0000000000000000000000003081 120.0
GZD1_k127_1775169_35 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000000000000000002438 97.0
GZD1_k127_1775169_36 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000001398 103.0
GZD1_k127_1775169_37 PUA domain K07575 - - 0.0000000000000000000187 101.0
GZD1_k127_1775169_38 ABC-type cobalt transport system, permease component K16925 - - 0.000000000001308 78.0
GZD1_k127_1775169_39 PQQ-like domain K00114 - 1.1.2.8 0.000000000001412 81.0
GZD1_k127_1775169_4 RNA-metabolising metallo-beta-lactamase K07041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 379.0
GZD1_k127_1775169_40 - - - - 0.0000000002008 64.0
GZD1_k127_1775169_41 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000008562 66.0
GZD1_k127_1775169_42 Belongs to the enoyl-CoA hydratase isomerase family K15016 - 1.1.1.35,4.2.1.17 0.000000005943 63.0
GZD1_k127_1775169_43 crossover junction endodeoxyribonuclease activity K03552 - 3.1.22.4 0.0000000634 58.0
GZD1_k127_1775169_44 SCP-2 sterol transfer family - - - 0.00000007876 59.0
GZD1_k127_1775169_45 exosome subunit K07581 - - 0.000001957 55.0
GZD1_k127_1775169_46 COGs COG3316 Transposase and inactivated derivatives - - - 0.000002392 52.0
GZD1_k127_1775169_47 Copper binding proteins, plastocyanin/azurin family - - - 0.00007794 54.0
GZD1_k127_1775169_48 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.0001282 51.0
GZD1_k127_1775169_5 COG1121 ABC-type Mn Zn transport systems ATPase component K02074,K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 372.0
GZD1_k127_1775169_6 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 367.0
GZD1_k127_1775169_7 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 348.0
GZD1_k127_1775169_8 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 348.0
GZD1_k127_1775169_9 COG1108 ABC-type Mn2 Zn2 transport systems permease components K02075,K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 334.0
GZD1_k127_1778612_0 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 5.426e-245 772.0
GZD1_k127_1778612_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 565.0
GZD1_k127_1778612_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 539.0
GZD1_k127_1778612_3 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 445.0
GZD1_k127_1778612_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000002506 252.0
GZD1_k127_1778612_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000636 182.0
GZD1_k127_1778612_6 DNA-3-methyladenine glycosylase K01247 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0045007,GO:0046483,GO:0050896,GO:0051716,GO:0052820,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.00000000000000000000000000000000000000000001099 171.0
GZD1_k127_1778612_7 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000008179 99.0
GZD1_k127_1778612_8 Archaeal transcriptional regulator TrmB - - - 0.0000000000007919 78.0
GZD1_k127_1799034_0 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000001195 138.0
GZD1_k127_1799034_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000006352 68.0
GZD1_k127_1799034_2 PFAM Glutaredoxin 2 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000573 63.0
GZD1_k127_181884_0 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 439.0
GZD1_k127_181884_1 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity K05592 GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 368.0
GZD1_k127_181884_10 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000000001491 198.0
GZD1_k127_181884_11 ERCC4 domain K10848 - - 0.000000000000000000000000000000000000000002751 164.0
GZD1_k127_181884_12 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000268 129.0
GZD1_k127_181884_13 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000001218 130.0
GZD1_k127_181884_14 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000002683 123.0
GZD1_k127_181884_15 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.000000000000000000000000002824 120.0
GZD1_k127_181884_16 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000292 115.0
GZD1_k127_181884_17 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000007709 123.0
GZD1_k127_181884_18 Ribosomal L37ae protein family K02921 - - 0.000000000000000126 82.0
GZD1_k127_181884_19 - - - - 0.000000000000002322 80.0
GZD1_k127_181884_2 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 328.0
GZD1_k127_181884_20 PFAM flavin reductase domain protein FMN-binding - - - 0.00000000000000321 83.0
GZD1_k127_181884_21 pyrroloquinoline quinone binding - - - 0.0000000000001341 75.0
GZD1_k127_181884_22 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.000000002667 67.0
GZD1_k127_181884_23 Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - 0.000009714 56.0
GZD1_k127_181884_24 COG3316 Transposase and inactivated derivatives - - - 0.0002488 47.0
GZD1_k127_181884_3 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 328.0
GZD1_k127_181884_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 294.0
GZD1_k127_181884_5 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004918 275.0
GZD1_k127_181884_6 ABC-type cobalt transport system ATPase component K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000228 270.0
GZD1_k127_181884_7 PFAM ABC transporter related K16785,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002064 254.0
GZD1_k127_181884_8 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002874 250.0
GZD1_k127_181884_9 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.000000000000000000000000000000000000000000000000000000000000000000007001 240.0
GZD1_k127_1822058_0 MGS-like domain K01955 - 6.3.5.5 0.0 1097.0
GZD1_k127_1822058_1 Belongs to the RtcB family K14415 - 6.5.1.3 5.068e-210 662.0
GZD1_k127_1822058_10 Lysine biosynthesis K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009185 283.0
GZD1_k127_1822058_11 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005348 274.0
GZD1_k127_1822058_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004882 227.0
GZD1_k127_1822058_13 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000003571 228.0
GZD1_k127_1822058_14 protein (ATP-grasp superfamily) K07159 - - 0.0000000000000000000000000000000000000000000000000003586 197.0
GZD1_k127_1822058_15 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000002307 143.0
GZD1_k127_1822058_16 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000006096 136.0
GZD1_k127_1822058_17 - - - - 0.0000000000000000000399 96.0
GZD1_k127_1822058_18 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000004359 100.0
GZD1_k127_1822058_19 lysine biosynthesis protein LysW K05826 - - 0.0000000000000006159 78.0
GZD1_k127_1822058_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 477.0
GZD1_k127_1822058_20 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000003176 86.0
GZD1_k127_1822058_21 lysine biosynthesis protein LysW K05826 - - 0.000000000005396 69.0
GZD1_k127_1822058_3 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 437.0
GZD1_k127_1822058_4 carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 426.0
GZD1_k127_1822058_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008835 431.0
GZD1_k127_1822058_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 383.0
GZD1_k127_1822058_7 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 325.0
GZD1_k127_1822058_8 Lysine biosynthesis K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 314.0
GZD1_k127_1822058_9 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 287.0
GZD1_k127_1845648_0 HELICc2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 359.0
GZD1_k127_1845648_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 289.0
GZD1_k127_1845648_10 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.0000000000000000000008144 98.0
GZD1_k127_1845648_11 Major Facilitator Superfamily - - - 0.00000000000000000001109 105.0
GZD1_k127_1845648_12 SnoaL-like domain - - - 0.0000000000000000003015 91.0
GZD1_k127_1845648_13 COG1522 Transcriptional regulators - - - 0.000000000000008846 76.0
GZD1_k127_1845648_14 sequence-specific DNA binding - - - 0.00000000000002849 84.0
GZD1_k127_1845648_15 Protein of unknown function (DUF998) - - - 0.0000000006843 67.0
GZD1_k127_1845648_16 CorA-like Mg2+ transporter protein K03284 - - 0.0000001138 59.0
GZD1_k127_1845648_17 belongs to the nudix hydrolase family K03574 - 3.6.1.55 0.0000004888 58.0
GZD1_k127_1845648_18 Homocitrate synthase K01649 - 2.3.3.13 0.000003364 53.0
GZD1_k127_1845648_19 transcriptional regulator K03718 - - 0.00000911 57.0
GZD1_k127_1845648_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001371 289.0
GZD1_k127_1845648_3 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000000000000000002237 205.0
GZD1_k127_1845648_4 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000001274 212.0
GZD1_k127_1845648_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000007058 192.0
GZD1_k127_1845648_6 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000001002 172.0
GZD1_k127_1845648_7 Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000000000000001745 170.0
GZD1_k127_1845648_8 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.0000000000000000000000000000000000000000001033 164.0
GZD1_k127_1845648_9 - - - - 0.000000000000000000000000001525 124.0
GZD1_k127_1856681_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 391.0
GZD1_k127_1856681_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000003716 179.0
GZD1_k127_1856681_2 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000003097 163.0
GZD1_k127_1856681_3 Alpha/beta hydrolase family - - - 0.0000005732 51.0
GZD1_k127_1856681_4 PFAM GCN5-related N-acetyltransferase - - - 0.00004443 53.0
GZD1_k127_1923572_0 RNase L inhibitor, RLI K06174 - - 2.495e-207 661.0
GZD1_k127_1978708_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000004678 171.0
GZD1_k127_1978708_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000005773 100.0
GZD1_k127_1978708_2 Sugar (and other) transporter - - - 0.000000000003948 78.0
GZD1_k127_2015026_0 PFAM PAC2 family K06869 - - 0.000000000000000001945 94.0
GZD1_k127_2063546_0 Histone acetyltransferase K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 463.0
GZD1_k127_2063546_1 SMC proteins Flexible Hinge Domain K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 467.0
GZD1_k127_2063546_10 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000001786 141.0
GZD1_k127_2063546_11 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000002143 140.0
GZD1_k127_2063546_12 segregation and condensation protein K06024 - - 0.00000000000000000000000000000000004882 141.0
GZD1_k127_2063546_13 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000003538 121.0
GZD1_k127_2063546_14 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000003489 110.0
GZD1_k127_2063546_15 Glycine cleavage H-protein K02437 - - 0.0000000000000000001785 97.0
GZD1_k127_2063546_16 RNA-binding protein involved in rRNA processing K07569 - - 0.0000000000001841 72.0
GZD1_k127_2063546_17 Ribosomal protein S30 K02983 - - 0.00000001634 57.0
GZD1_k127_2063546_18 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000004241 55.0
GZD1_k127_2063546_19 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.000004197 58.0
GZD1_k127_2063546_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 400.0
GZD1_k127_2063546_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 402.0
GZD1_k127_2063546_4 factor TFIIB K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009486 253.0
GZD1_k127_2063546_5 NOSIC (NUC001) domain K14564 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002594 258.0
GZD1_k127_2063546_6 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000000000000000000001994 243.0
GZD1_k127_2063546_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000002847 220.0
GZD1_k127_2063546_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000436 179.0
GZD1_k127_2063546_9 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000001745 177.0
GZD1_k127_2129659_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.999e-245 772.0
GZD1_k127_2129659_1 COG1960 Acyl-CoA dehydrogenases K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 358.0
GZD1_k127_2129659_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 316.0
GZD1_k127_2129659_3 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000005958 181.0
GZD1_k127_2129659_4 protein conserved in archaea - - - 0.000000000000000000000000000007508 131.0
GZD1_k127_2129659_5 ArgK protein K07588 - - 0.0000000000000000000000002987 108.0
GZD1_k127_2129659_6 transcriptional - - - 0.0000000000000000000007188 99.0
GZD1_k127_2129659_7 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000001578 93.0
GZD1_k127_2129659_8 UPF0182 protein K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000094 79.0
GZD1_k127_2129659_9 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.00002112 55.0
GZD1_k127_2130360_0 PFAM Type II IV secretion system protein K02283 - - 0.0000000000000000000005299 111.0
GZD1_k127_2153176_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 597.0
GZD1_k127_2153176_1 Initiation factor K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 501.0
GZD1_k127_2153176_2 Nucleotidyltransferase domain K07076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 313.0
GZD1_k127_2153176_3 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003059 268.0
GZD1_k127_2153176_4 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000000000006595 137.0
GZD1_k127_2153176_5 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.00000000000000000000000000001725 120.0
GZD1_k127_2153176_6 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000178 78.0
GZD1_k127_2153176_7 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000002735 78.0
GZD1_k127_2153176_8 - - - - 0.0000000001254 65.0
GZD1_k127_2153176_9 Nucleotide binding protein, PINc K07158 GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00001253 53.0
GZD1_k127_219087_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.08e-199 626.0
GZD1_k127_219087_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 544.0
GZD1_k127_2227198_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 382.0
GZD1_k127_2227198_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 344.0
GZD1_k127_2227198_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000002201 192.0
GZD1_k127_2227198_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000004763 177.0
GZD1_k127_2227198_4 PFAM CBS domain containing protein - - - 0.000000000000000000000000315 111.0
GZD1_k127_2227198_5 ABC transporter, solute-binding protein K02012 - - 0.00000000001149 76.0
GZD1_k127_2227198_6 Glucose / Sorbosone dehydrogenase - - - 0.000000004731 65.0
GZD1_k127_2227198_8 - K00368 - 1.7.2.1 0.0001163 51.0
GZD1_k127_2247435_0 Type II secretion system K07333 - - 0.0000000000000000000000000000000000001688 149.0
GZD1_k127_2247435_1 Winged helix-turn-helix - - - 0.00000000000000000000001348 112.0
GZD1_k127_2247435_2 - - - - 0.00009563 55.0
GZD1_k127_224911_0 PFAM Rh family protein ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 576.0
GZD1_k127_224911_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 475.0
GZD1_k127_224911_10 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000966 160.0
GZD1_k127_224911_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000008335 141.0
GZD1_k127_224911_12 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000002155 132.0
GZD1_k127_224911_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000009013 123.0
GZD1_k127_224911_14 Thioesterase K07107 - - 0.00000000000000000000000000173 116.0
GZD1_k127_224911_15 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.0000000000000000000003735 100.0
GZD1_k127_224911_16 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000004889 97.0
GZD1_k127_224911_17 involved in cell wall biogenesis K00721 - 2.4.1.83 0.00000000000000000003009 101.0
GZD1_k127_224911_18 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000007525 85.0
GZD1_k127_224911_19 AMP binding - - - 0.000000000329 68.0
GZD1_k127_224911_2 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 400.0
GZD1_k127_224911_20 Pyridoxamine 5'-phosphate oxidase - - - 0.00000001478 63.0
GZD1_k127_224911_21 - - - - 0.0007833 48.0
GZD1_k127_224911_3 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 386.0
GZD1_k127_224911_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000065 274.0
GZD1_k127_224911_5 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000001509 266.0
GZD1_k127_224911_6 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000006201 208.0
GZD1_k127_224911_7 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000001593 210.0
GZD1_k127_224911_8 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000002056 181.0
GZD1_k127_224911_9 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000001785 170.0
GZD1_k127_2295781_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.189e-214 674.0
GZD1_k127_2295781_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 575.0
GZD1_k127_2295781_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000001381 164.0
GZD1_k127_2358892_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 411.0
GZD1_k127_2358892_1 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000004797 184.0
GZD1_k127_2358892_2 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275,K02826,K15864 - 1.10.3.12,1.7.2.1,1.7.99.1,1.9.3.1 0.0000000000000000000000000000000000000000007422 164.0
GZD1_k127_2358892_3 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000001581 123.0
GZD1_k127_2358892_4 protein with SCP PR1 domains - - - 0.000000000000000000000006215 115.0
GZD1_k127_2358892_5 snRNP Sm proteins K04796 - - 0.00000000000000000000007767 100.0
GZD1_k127_2377544_0 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000009463 207.0
GZD1_k127_2377544_1 VIT family - - - 0.000000000000000000005851 104.0
GZD1_k127_2381396_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 504.0
GZD1_k127_2381396_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 387.0
GZD1_k127_2381396_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749,K13542 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000005308 235.0
GZD1_k127_2381396_3 Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000002967 217.0
GZD1_k127_2381396_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.0000000000000000000000000000000000000000007153 168.0
GZD1_k127_2381396_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000005042 165.0
GZD1_k127_2381396_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000001562 124.0
GZD1_k127_2398347_0 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0008964,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0071704 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 480.0
GZD1_k127_2398347_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 432.0
GZD1_k127_2398347_2 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01911 - 6.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 373.0
GZD1_k127_2398347_3 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 346.0
GZD1_k127_2398347_4 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001803 291.0
GZD1_k127_2398347_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000002336 252.0
GZD1_k127_2398347_6 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000001204 225.0
GZD1_k127_2398347_7 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000001186 220.0
GZD1_k127_2398347_8 Transcriptional regulator - - - 0.000000000000000000000002898 106.0
GZD1_k127_2452561_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 494.0
GZD1_k127_2452561_1 PFAM Quinolinate phosphoribosyl transferase K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 365.0
GZD1_k127_2452561_10 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000008976 92.0
GZD1_k127_2452561_11 PIN domain of ribonuclease K07060 - - 0.00000000000000000009002 95.0
GZD1_k127_2452561_12 metallopeptidase activity K03933 - - 0.0000000003881 66.0
GZD1_k127_2452561_13 heme binding - - - 0.000001204 60.0
GZD1_k127_2452561_2 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000003464 239.0
GZD1_k127_2452561_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916,K01950 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000007092 243.0
GZD1_k127_2452561_4 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000002385 233.0
GZD1_k127_2452561_5 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000001442 197.0
GZD1_k127_2452561_6 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000001198 147.0
GZD1_k127_2452561_7 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000000000000000006561 111.0
GZD1_k127_2452561_8 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000008037 117.0
GZD1_k127_2452561_9 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.000000000000000000004425 102.0
GZD1_k127_2491393_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 431.0
GZD1_k127_2491393_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 313.0
GZD1_k127_2491393_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 304.0
GZD1_k127_2491393_3 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000003227 181.0
GZD1_k127_2491393_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000005058 162.0
GZD1_k127_2494577_0 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 462.0
GZD1_k127_2494577_1 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 381.0
GZD1_k127_2494577_2 Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000001573 252.0
GZD1_k127_2494577_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000258 190.0
GZD1_k127_2494577_5 glyoxalase III activity - - - 0.000000000000000000000000000003288 130.0
GZD1_k127_2494577_6 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000001602 118.0
GZD1_k127_2494577_7 cyclic nucleotide binding K09766,K10914 - - 0.0000000000000000000000009584 108.0
GZD1_k127_2494577_8 - - - - 0.0000000000000000001845 94.0
GZD1_k127_2499561_0 small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 440.0
GZD1_k127_2499561_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000002287 181.0
GZD1_k127_2499561_2 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000005072 156.0
GZD1_k127_2499561_3 CoA binding domain K06929 - - 0.000000000000000000000000000000000002637 143.0
GZD1_k127_2499561_5 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000006067 99.0
GZD1_k127_2499561_6 Transcriptional regulator K07332 - - 0.0000000000000000001082 99.0
GZD1_k127_2499561_7 - - - - 0.00000000001817 71.0
GZD1_k127_2604331_0 Diphthamide biosynthesis K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000001315 222.0
GZD1_k127_2604331_1 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000008055 179.0
GZD1_k127_2604331_2 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000008451 113.0
GZD1_k127_2604331_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K02528 - 2.1.1.182 0.00000000000000000000003728 104.0
GZD1_k127_2604331_4 Putative RNA methylase family UPF0020 - - - 0.00000000000000000005182 103.0
GZD1_k127_2627215_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 554.0
GZD1_k127_2627215_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 484.0
GZD1_k127_2627215_10 - - - - 0.0000000000000000000002237 105.0
GZD1_k127_2627215_11 Winged helix-turn-helix - - - 0.0000000000000000009921 88.0
GZD1_k127_2627215_12 CAAX protease self-immunity - - - 0.00000000000000004394 94.0
GZD1_k127_2627215_13 Electron transfer flavoprotein K03521 - - 0.0000000000000008842 90.0
GZD1_k127_2627215_14 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000008984 57.0
GZD1_k127_2627215_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 436.0
GZD1_k127_2627215_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 318.0
GZD1_k127_2627215_4 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 307.0
GZD1_k127_2627215_5 HI0933-like protein K00313 - - 0.00000000000000000000000000000000000000000000000000000000001031 228.0
GZD1_k127_2627215_6 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000001183 212.0
GZD1_k127_2627215_7 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000000000000000000000005179 169.0
GZD1_k127_2627215_8 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.000000000000000000000000000000000000000000003926 173.0
GZD1_k127_2627215_9 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000001083 130.0
GZD1_k127_2636669_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 340.0
GZD1_k127_2636669_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000000005887 183.0
GZD1_k127_2636669_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000003839 160.0
GZD1_k127_2636669_3 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.000000000000000000000009689 103.0
GZD1_k127_2675955_0 PFAM CoA-binding domain protein K01905 - 6.2.1.13 3.92e-241 764.0
GZD1_k127_2675955_1 - - - - 0.00000000000000000006977 97.0
GZD1_k127_2675955_2 Belongs to the universal stress protein A family - - - 0.00000000000000005175 88.0
GZD1_k127_2675955_3 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000003552 87.0
GZD1_k127_2675955_4 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000006002 81.0
GZD1_k127_2675955_5 DUF72 domain containing protein - - - 0.00000000000004751 74.0
GZD1_k127_2675955_6 transcriptional regulators - - - 0.00000028 59.0
GZD1_k127_2675955_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000001828 51.0
GZD1_k127_2675955_8 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00001868 55.0
GZD1_k127_2685232_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.713e-274 873.0
GZD1_k127_2685232_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 7.211e-229 744.0
GZD1_k127_2685232_2 Related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000008245 230.0
GZD1_k127_2685232_3 phosphoribosyltransferases - - - 0.0000000000000000000000000000000000000000000000000007211 200.0
GZD1_k127_2685232_4 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000007215 188.0
GZD1_k127_2685232_5 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000001365 179.0
GZD1_k127_2685232_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000006748 93.0
GZD1_k127_2685232_7 - - - - 0.00000000000000001446 83.0
GZD1_k127_2685232_8 spore germination - - - 0.0000000000003637 79.0
GZD1_k127_2685232_9 Uncharacterized ACR, COG1430 K09005 - - 0.0001721 50.0
GZD1_k127_2694889_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 366.0
GZD1_k127_2694889_1 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 353.0
GZD1_k127_2694889_2 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000003176 195.0
GZD1_k127_2694889_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000003438 173.0
GZD1_k127_2694889_4 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000006796 167.0
GZD1_k127_2694889_5 transferase activity, transferring glycosyl groups K14597 - - 0.0000000000000000000000000000000001003 147.0
GZD1_k127_2694889_6 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000005904 121.0
GZD1_k127_2694889_7 Protein of unknown function (DUF1294) - - - 0.000000000272 64.0
GZD1_k127_2694889_8 - - - - 0.000002624 58.0
GZD1_k127_2694889_9 Glyoxalase-like domain - - - 0.000005802 53.0
GZD1_k127_2772104_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 477.0
GZD1_k127_2772104_1 Cytochrome b subunit of the bc complex K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 436.0
GZD1_k127_2772104_10 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000001505 186.0
GZD1_k127_2772104_11 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000004964 177.0
GZD1_k127_2772104_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000001394 165.0
GZD1_k127_2772104_13 PFAM Rieske 2Fe-2S domain K00411 - 1.10.2.2 0.000000000000000000000000000000001875 139.0
GZD1_k127_2772104_14 Peptidase family M50 - - - 0.00000000000000000000000001948 123.0
GZD1_k127_2772104_15 Domain of unknown function (DUF2088) - - - 0.000000000000000000005988 105.0
GZD1_k127_2772104_16 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000009503 79.0
GZD1_k127_2772104_17 - K02339 - 2.7.7.7 0.000000000206 69.0
GZD1_k127_2772104_18 PFAM blue (type 1) copper domain protein - - - 0.0000002557 61.0
GZD1_k127_2772104_19 - - - - 0.0000007482 53.0
GZD1_k127_2772104_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 411.0
GZD1_k127_2772104_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 386.0
GZD1_k127_2772104_4 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 385.0
GZD1_k127_2772104_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 368.0
GZD1_k127_2772104_6 TIGRFAM oligopeptide dipeptide ABC transporter K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 344.0
GZD1_k127_2772104_7 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 311.0
GZD1_k127_2772104_8 PFAM type II secretion system protein E K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001015 297.0
GZD1_k127_2772104_9 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000001611 192.0
GZD1_k127_2804060_0 collagen metabolic process K08677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 551.0
GZD1_k127_2804060_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 477.0
GZD1_k127_2804060_10 Ser thr protein kinase K07176 - - 0.00000000000000000000000000000000000000000000005786 179.0
GZD1_k127_2804060_11 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000001654 151.0
GZD1_k127_2804060_12 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000079 97.0
GZD1_k127_2804060_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 428.0
GZD1_k127_2804060_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 335.0
GZD1_k127_2804060_4 Cytochrome b - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 316.0
GZD1_k127_2804060_5 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 304.0
GZD1_k127_2804060_6 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 299.0
GZD1_k127_2804060_7 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000285 201.0
GZD1_k127_2804060_8 PFAM Rieske 2Fe-2S domain - - - 0.00000000000000000000000000000000000000000000000000004165 194.0
GZD1_k127_2804060_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000013 179.0
GZD1_k127_2873046_0 TIGRFAM glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 522.0
GZD1_k127_2873046_1 PFAM Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000001782 263.0
GZD1_k127_2873046_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000004493 102.0
GZD1_k127_2873046_11 ribosomal protein K02883 - - 0.00000000000000001817 90.0
GZD1_k127_2873046_2 DNA-directed RNA polymerase, alpha subunit 40 kD subunit K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000614 245.0
GZD1_k127_2873046_3 PFAM S-layer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001407 250.0
GZD1_k127_2873046_4 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000004137 215.0
GZD1_k127_2873046_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000006165 209.0
GZD1_k127_2873046_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000006451 172.0
GZD1_k127_2873046_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000001365 169.0
GZD1_k127_2873046_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000008356 145.0
GZD1_k127_2873046_9 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000005943 143.0
GZD1_k127_2879737_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 4.534e-217 702.0
GZD1_k127_2879737_1 ABC transporter K02056,K06400 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 500.0
GZD1_k127_2879737_2 Amidinotransferase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 440.0
GZD1_k127_2879737_3 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 330.0
GZD1_k127_2879737_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000006657 234.0
GZD1_k127_2879737_5 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000002606 227.0
GZD1_k127_2879737_6 ABC-type transport system, periplasmic component surface lipoprotein K07335 - - 0.000000000000000000000009257 115.0
GZD1_k127_2879737_8 COG0517 FOG CBS domain - - - 0.000000006336 59.0
GZD1_k127_2879737_9 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000002065 60.0
GZD1_k127_294857_0 PFAM binding-protein-dependent transport systems inner membrane component K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000006484 242.0
GZD1_k127_294857_1 ABC-type molybdate transport system periplasmic K15495 - - 0.00000000000000000000000000000000000000000000000000000000000000002605 237.0
GZD1_k127_294857_2 ABC transporter K15497 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000247 197.0
GZD1_k127_294857_3 Domain of unknown function (DUF929) - - - 0.0000000000000000000000000000000000000000000001083 181.0
GZD1_k127_294857_4 regulatory protein LysR K02019 - - 0.00000000000000000000000002781 117.0
GZD1_k127_294857_5 WLM domain K07043 - - 0.000000000000000002088 94.0
GZD1_k127_294857_6 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00002731 51.0
GZD1_k127_294857_7 Vitamin K epoxide reductase family - - - 0.0001227 51.0
GZD1_k127_2996440_0 aconitate hydratase K01681 - 4.2.1.3 4.017e-309 974.0
GZD1_k127_2996440_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 608.0
GZD1_k127_2996440_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 437.0
GZD1_k127_2996440_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 438.0
GZD1_k127_2996440_4 Cysteine synthase K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 381.0
GZD1_k127_2996440_5 COG1522 Transcriptional regulators - - - 0.000000000002695 71.0
GZD1_k127_2996440_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex - - - 0.00000000000384 72.0
GZD1_k127_300741_0 Belongs to the MCM family K10726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 621.0
GZD1_k127_300741_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 616.0
GZD1_k127_300741_10 choline dehydrogenase activity K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000000001244 206.0
GZD1_k127_300741_11 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000003316 151.0
GZD1_k127_300741_12 - - - - 0.00000000000000000003097 98.0
GZD1_k127_300741_13 Methyltransferase small domain K02493 - 2.1.1.297 0.000000000000000001864 96.0
GZD1_k127_300741_15 Peptidase S8 and S53 subtilisin kexin sedolisin K13276,K17948 GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005623,GO:0016853,GO:0016854,GO:0016857,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 5.1.3.24 0.000000004597 68.0
GZD1_k127_300741_16 GINS complex protein K09723 - - 0.00003951 53.0
GZD1_k127_300741_17 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.0001063 54.0
GZD1_k127_300741_2 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 382.0
GZD1_k127_300741_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 341.0
GZD1_k127_300741_4 Replication factor C K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 303.0
GZD1_k127_300741_5 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 308.0
GZD1_k127_300741_6 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002478 267.0
GZD1_k127_300741_7 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000002867 224.0
GZD1_k127_300741_8 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000005513 217.0
GZD1_k127_300741_9 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000003995 196.0
GZD1_k127_3019081_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 452.0
GZD1_k127_3019081_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 385.0
GZD1_k127_3019081_10 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000131 70.0
GZD1_k127_3019081_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 301.0
GZD1_k127_3019081_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008835 300.0
GZD1_k127_3019081_4 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000002372 206.0
GZD1_k127_3019081_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000003611 191.0
GZD1_k127_3019081_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000001847 196.0
GZD1_k127_3019081_7 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000005165 156.0
GZD1_k127_3019081_8 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000204 150.0
GZD1_k127_3019081_9 ParB-like nuclease domain - - - 0.00000000000000004677 87.0
GZD1_k127_3037577_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000004367 179.0
GZD1_k127_3037577_1 COG0467 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.000000000000000000000000000006465 127.0
GZD1_k127_3037577_2 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - 0.0000000000000000869 93.0
GZD1_k127_3051086_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 352.0
GZD1_k127_3051086_1 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000003917 271.0
GZD1_k127_3051086_2 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000005132 223.0
GZD1_k127_3051086_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000009159 191.0
GZD1_k127_3051086_4 Membrane protein, UPF0016 and UPF0016 domain-containing - - - 0.00000000000299 74.0
GZD1_k127_3061723_0 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000003365 198.0
GZD1_k127_3061723_1 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000595 68.0
GZD1_k127_3061723_2 Cytoplasmic, score K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000624 57.0
GZD1_k127_3071010_0 glucosylceramidase activity - - - 0.000000004342 63.0
GZD1_k127_3098723_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 370.0
GZD1_k127_3098723_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 291.0
GZD1_k127_3098723_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01003,K01841 - 4.1.1.3,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001131 273.0
GZD1_k127_3098723_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000008479 213.0
GZD1_k127_3098723_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000001584 164.0
GZD1_k127_3098723_5 Conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000005546 159.0
GZD1_k127_3098723_6 HD domain K07023 - - 0.000000000000000000000000000000286 130.0
GZD1_k127_3098723_7 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000001187 121.0
GZD1_k127_3098723_8 RDD family - - - 0.00000004844 62.0
GZD1_k127_3098723_9 regulatory protein, arsR - - - 0.0000001109 62.0
GZD1_k127_309948_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 374.0
GZD1_k127_309948_1 helicase superfamily c-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002735 291.0
GZD1_k127_309948_2 ATPase family associated with various cellular activities (AAA) K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000002375 247.0
GZD1_k127_309948_3 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000002511 171.0
GZD1_k127_309948_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000001086 173.0
GZD1_k127_309948_5 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000001331 121.0
GZD1_k127_309948_6 regulatory protein, arsR - - - 0.00000000001673 73.0
GZD1_k127_3107334_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 410.0
GZD1_k127_3107334_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000002918 213.0
GZD1_k127_3181636_0 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000004455 225.0
GZD1_k127_3181636_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000001991 211.0
GZD1_k127_3181636_10 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000000001341 75.0
GZD1_k127_3181636_11 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0002695 49.0
GZD1_k127_3181636_12 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0003772 48.0
GZD1_k127_3181636_2 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.0000000000000000000000000000000000000000000000006394 183.0
GZD1_k127_3181636_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000007205 181.0
GZD1_k127_3181636_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000005791 175.0
GZD1_k127_3181636_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000005892 173.0
GZD1_k127_3181636_6 ribosomal protein K02912 - - 0.000000000000000000000000000000007727 132.0
GZD1_k127_3181636_7 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000001434 129.0
GZD1_k127_3181636_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000004887 113.0
GZD1_k127_3181636_9 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001124 82.0
GZD1_k127_3182352_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 520.0
GZD1_k127_3182352_1 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003855 278.0
GZD1_k127_3182352_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000002065 215.0
GZD1_k127_3182352_3 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic K02051 - - 0.000000000000000000000000136 117.0
GZD1_k127_3182352_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000002295 82.0
GZD1_k127_3182352_5 Belongs to the P(II) protein family K04751 - - 0.0000000001384 66.0
GZD1_k127_3182352_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000005781 64.0
GZD1_k127_3182352_7 - - - - 0.0001322 50.0
GZD1_k127_3186141_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 526.0
GZD1_k127_3186141_1 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000001055 193.0
GZD1_k127_3186141_2 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000007124 196.0
GZD1_k127_3186141_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000004037 159.0
GZD1_k127_3186141_4 Belongs to the peptidase M48B family K03799 - - 0.000000000001094 68.0
GZD1_k127_3207265_0 Pro-kumamolisin, activation domain - - - 2.432e-215 715.0
GZD1_k127_3207265_1 DEAD H associated K03724 - - 2.026e-197 648.0
GZD1_k127_3207265_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000001014 242.0
GZD1_k127_3207265_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000001776 238.0
GZD1_k127_3207265_4 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000423 194.0
GZD1_k127_3207265_5 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000009042 129.0
GZD1_k127_3207265_6 PFAM histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000001632 127.0
GZD1_k127_3207265_7 Protein of unknown function (DUF971) - - - 0.00000000000000000002267 96.0
GZD1_k127_3207265_8 Bacterial regulatory proteins, tetR family - - - 0.00000000001615 72.0
GZD1_k127_3207265_9 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000003769 72.0
GZD1_k127_324080_0 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000000000000000000000007102 208.0
GZD1_k127_324080_1 Mechanosensitive ion channel - - - 0.0000000001072 70.0
GZD1_k127_324080_2 - - - - 0.00000001178 65.0
GZD1_k127_3294919_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 497.0
GZD1_k127_3294919_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 472.0
GZD1_k127_3355360_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000001748 196.0
GZD1_k127_3355360_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000007865 149.0
GZD1_k127_3355360_2 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000005393 119.0
GZD1_k127_3355360_3 TatD related DNase K03424 - - 0.000000000000000000001193 104.0
GZD1_k127_3355360_4 PFAM THUMP domain protein K06963 - - 0.0000000000000000005111 93.0
GZD1_k127_3355360_5 transcription factor (CBF NF-Y) - - - 0.000000000000000009525 85.0
GZD1_k127_3355360_6 ribosomal protein K02962 - - 0.0000001051 59.0
GZD1_k127_3355360_7 - - - - 0.0000001658 55.0
GZD1_k127_3355360_8 phosphatidylinositol metabolic process - - - 0.0001561 53.0
GZD1_k127_3365989_0 metallophosphoesterase K07096,K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002391 248.0
GZD1_k127_3365989_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003131 233.0
GZD1_k127_3365989_2 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001088 218.0
GZD1_k127_3365989_3 - - - - 0.0000000000000000000000000000000000000000000001118 181.0
GZD1_k127_3365989_4 - - - - 0.00000000000000000000000001911 119.0
GZD1_k127_3398742_0 SMART DNA mismatch repair protein MutS, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 593.0
GZD1_k127_3398742_1 PFAM DNA mismatch repair protein MutS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 573.0
GZD1_k127_3398742_10 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000002635 169.0
GZD1_k127_3398742_11 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000004401 149.0
GZD1_k127_3398742_12 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000002866 132.0
GZD1_k127_3398742_14 ATP synthase subunit C K02124 - - 0.000000000000000000000000003183 112.0
GZD1_k127_3398742_15 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000003666 114.0
GZD1_k127_3398742_16 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.00000000000000000000000004469 115.0
GZD1_k127_3398742_17 Patch-forming domain C2 of tRNA-guanine transglycosylase K07398 - - 0.000000000000000000000001591 109.0
GZD1_k127_3398742_18 Psort location Cytoplasmic, score - - - 0.0000000000000000000692 96.0
GZD1_k127_3398742_19 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000001347 91.0
GZD1_k127_3398742_2 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 328.0
GZD1_k127_3398742_20 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759,K15772 - 4.4.1.5 0.0000000000000001524 85.0
GZD1_k127_3398742_21 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000003635 87.0
GZD1_k127_3398742_22 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000005399 82.0
GZD1_k127_3398742_23 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000002666 79.0
GZD1_k127_3398742_24 Hemerythrin HHE cation binding K07322 - - 0.0000000001496 72.0
GZD1_k127_3398742_25 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000004945 53.0
GZD1_k127_3398742_26 Mo-molybdopterin cofactor metabolic process K03636,K03637,K03752,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77,2.8.1.12,4.6.1.17 0.0008313 49.0
GZD1_k127_3398742_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 323.0
GZD1_k127_3398742_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 316.0
GZD1_k127_3398742_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004387 270.0
GZD1_k127_3398742_6 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000000000000000000000000000003753 232.0
GZD1_k127_3398742_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000007846 234.0
GZD1_k127_3398742_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000008991 235.0
GZD1_k127_3398742_9 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000001468 239.0
GZD1_k127_340125_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 561.0
GZD1_k127_340125_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 478.0
GZD1_k127_340125_10 proteolysis - - - 0.0000000000000000000000000001193 123.0
GZD1_k127_340125_11 - - - - 0.00000131 61.0
GZD1_k127_340125_2 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 388.0
GZD1_k127_340125_3 Papain cysteine protease family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 323.0
GZD1_k127_340125_4 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 325.0
GZD1_k127_340125_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 317.0
GZD1_k127_340125_6 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001103 263.0
GZD1_k127_340125_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000005731 199.0
GZD1_k127_340125_8 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000006117 173.0
GZD1_k127_340125_9 nitric oxide dioxygenase activity K21405 - - 0.000000000000000000000000000000000000003411 157.0
GZD1_k127_3465468_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 617.0
GZD1_k127_3465468_1 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004643 284.0
GZD1_k127_3465468_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000353 58.0
GZD1_k127_3489601_0 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000004316 269.0
GZD1_k127_3489601_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001712 264.0
GZD1_k127_3489601_2 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000174 246.0
GZD1_k127_3489601_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000008982 116.0
GZD1_k127_3489601_4 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000009675 106.0
GZD1_k127_3489601_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000003326 90.0
GZD1_k127_3525729_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 438.0
GZD1_k127_3525729_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 309.0
GZD1_k127_3525729_2 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000001908 222.0
GZD1_k127_3525729_3 - - - - 0.00000000000000000000000000000000000000001177 165.0
GZD1_k127_3525729_4 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.000000000000000000000000000000000000000964 158.0
GZD1_k127_3525729_5 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000003053 151.0
GZD1_k127_3536307_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 369.0
GZD1_k127_3536307_1 Protein of unknown function (DUF1512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 344.0
GZD1_k127_3536307_2 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000004651 216.0
GZD1_k127_3536307_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000146 181.0
GZD1_k127_3536307_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000004897 186.0
GZD1_k127_3536307_5 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000136 90.0
GZD1_k127_3536307_6 Putative ATP-binding cassette K01992 - - 0.0007971 52.0
GZD1_k127_3537693_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 4.688e-291 911.0
GZD1_k127_3537693_1 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000005483 181.0
GZD1_k127_3537693_2 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000222 107.0
GZD1_k127_3537693_3 ATPase HMA5 K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.54 0.00000001363 59.0
GZD1_k127_3537693_4 - - - - 0.00000006309 59.0
GZD1_k127_3582490_0 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001854 276.0
GZD1_k127_3582490_1 Dienelactone hydrolase family K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000002418 239.0
GZD1_k127_3582490_10 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000005784 74.0
GZD1_k127_3582490_11 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000002087 77.0
GZD1_k127_3582490_12 Hypothetical methyltransferase - - - 0.000000000002765 75.0
GZD1_k127_3582490_13 - - - - 0.000000003398 66.0
GZD1_k127_3582490_14 DNA polymerase K02347 - - 0.00000002788 62.0
GZD1_k127_3582490_16 toxin-antitoxin pair type II binding - - - 0.000001322 53.0
GZD1_k127_3582490_17 Tfp pilus assembly protein FimV - - - 0.00001274 55.0
GZD1_k127_3582490_18 Winged helix-turn-helix DNA-binding - - - 0.0001453 51.0
GZD1_k127_3582490_19 PIN domain - - - 0.0005 48.0
GZD1_k127_3582490_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000989 238.0
GZD1_k127_3582490_3 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000003048 217.0
GZD1_k127_3582490_4 ketosteroid isomerase - - - 0.000000000000000000000000000000000000000000000000000000001661 207.0
GZD1_k127_3582490_5 HELICc2 - - - 0.00000000000000000000000000000151 133.0
GZD1_k127_3582490_6 metal-binding integral membrane protein - - - 0.000000000000000000000000000007418 129.0
GZD1_k127_3582490_7 NMT1-like family K02051 - - 0.00000000000000000000000006239 120.0
GZD1_k127_3582490_8 PFAM CBS domain containing protein - - - 0.000000000000000003969 90.0
GZD1_k127_3582490_9 Major Facilitator Superfamily - - - 0.000000000000000756 90.0
GZD1_k127_3602008_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 376.0
GZD1_k127_3602008_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 369.0
GZD1_k127_3602008_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 367.0
GZD1_k127_3602008_3 Blue copper protein - - - 0.00000000000000000000000000000000000000000001116 172.0
GZD1_k127_360210_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 401.0
GZD1_k127_360210_1 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 314.0
GZD1_k127_360210_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
GZD1_k127_3719385_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 419.0
GZD1_k127_3719385_1 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 399.0
GZD1_k127_3719385_2 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000001907 224.0
GZD1_k127_3719385_3 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.0000000000000000002374 94.0
GZD1_k127_3799427_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.957e-200 636.0
GZD1_k127_3799427_1 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002527 267.0
GZD1_k127_3799427_2 Thiamine-phosphate synthase K22206 - - 0.000000000000000000000000000003758 131.0
GZD1_k127_380483_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 381.0
GZD1_k127_380483_1 PFAM NAD-dependent epimerase dehydratase K01784,K08678 - 4.1.1.35,5.1.3.2 0.000000000000000000000000000000000000000722 160.0
GZD1_k127_380483_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000003237 128.0
GZD1_k127_380483_3 - - - - 0.0000000000000000000000009445 113.0
GZD1_k127_380483_5 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.0004016 49.0
GZD1_k127_3814207_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 556.0
GZD1_k127_3814207_1 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000004968 220.0
GZD1_k127_3814207_2 glycosyl transferase family K01001 - 2.7.8.15 0.00000000000000000000000000000000000000000000000004573 191.0
GZD1_k127_3814207_3 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.00000000000000000000000000000000004542 139.0
GZD1_k127_3814207_4 Dual specificity phosphatase, catalytic domain K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000000000000003538 128.0
GZD1_k127_3814207_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000773 77.0
GZD1_k127_3816741_0 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 520.0
GZD1_k127_3816741_1 Protein of unknown function (DUF790) K09744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 351.0
GZD1_k127_3816741_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 294.0
GZD1_k127_3816741_3 glucosylceramidase activity - - - 0.0000001353 59.0
GZD1_k127_3825802_0 PFAM Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 414.0
GZD1_k127_3825802_1 Belongs to the phosphohexose mutase family K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 394.0
GZD1_k127_3825802_2 Lyase K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 361.0
GZD1_k127_3825802_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 319.0
GZD1_k127_3825802_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007395 262.0
GZD1_k127_3825802_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000004748 245.0
GZD1_k127_3825802_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000001025 171.0
GZD1_k127_3825802_7 - - - - 0.0000000006524 67.0
GZD1_k127_38552_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000001452 147.0
GZD1_k127_38552_1 ABC-type sugar transport systems permease components K02025 - - 0.000000000000000000000000000187 127.0
GZD1_k127_38552_2 SET domain K07117 - - 0.000000000000000000006657 99.0
GZD1_k127_38552_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00006981 52.0
GZD1_k127_3859983_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 376.0
GZD1_k127_3859983_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
GZD1_k127_3913316_0 domain protein - - - 0.000000000006828 79.0
GZD1_k127_3920983_0 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.000000000000000000000000000000652 141.0
GZD1_k127_3920983_1 pre-rRNA processing protein involved in ribosome biogenesis K09140 GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000001142 83.0
GZD1_k127_3920983_2 COG1522 Transcriptional regulators - - - 0.00000000000006237 72.0
GZD1_k127_3920983_3 pre-rRNA processing protein involved in ribosome biogenesis K09140 GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000004945 61.0
GZD1_k127_3920983_4 Membrane domain of glycerophosphoryl diester phosphodiesterase - - - 0.000001472 59.0
GZD1_k127_3936822_0 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 340.0
GZD1_k127_3936822_1 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 325.0
GZD1_k127_3936822_2 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000004954 61.0
GZD1_k127_3960624_0 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 464.0
GZD1_k127_3960624_1 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002901 268.0
GZD1_k127_3960624_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000001413 158.0
GZD1_k127_3960624_3 GH3 auxin-responsive promoter - - - 0.000000000000003533 85.0
GZD1_k127_3960624_4 acid phosphatase activity - - - 0.0002295 48.0
GZD1_k127_3966060_0 PFAM Beta propeller domain K14475 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002691 278.0
GZD1_k127_3966060_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000468 168.0
GZD1_k127_3966060_2 Protein of unknown function DUF131 - - - 0.00000000004904 66.0
GZD1_k127_3982070_0 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 523.0
GZD1_k127_3982070_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759,K22503 - 6.1.1.12,6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 454.0
GZD1_k127_3982070_10 Transcriptional regulator, TrmB - - - 0.00000003168 66.0
GZD1_k127_3982070_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 324.0
GZD1_k127_3982070_3 ATP-grasp domain K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 306.0
GZD1_k127_3982070_4 conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000000000000000001385 184.0
GZD1_k127_3982070_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000009821 183.0
GZD1_k127_3982070_6 Transcription elongation factor - - - 0.00000000000000000000000000000001754 140.0
GZD1_k127_3982070_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 0.00000000000002209 80.0
GZD1_k127_3982070_8 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000006291 84.0
GZD1_k127_3982070_9 Conserved protein implicated in secretion - - - 0.00000000001762 75.0
GZD1_k127_3996419_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 379.0
GZD1_k127_3996419_1 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 295.0
GZD1_k127_3996419_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000003692 89.0
GZD1_k127_4050030_0 PFAM tRNA synthetase, class II (D, K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 382.0
GZD1_k127_4050030_1 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 289.0
GZD1_k127_4050030_10 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000001379 59.0
GZD1_k127_4050030_11 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.000007176 55.0
GZD1_k127_4050030_12 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00002168 56.0
GZD1_k127_4050030_2 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005296 248.0
GZD1_k127_4050030_3 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000008784 213.0
GZD1_k127_4050030_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000005454 209.0
GZD1_k127_4050030_5 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000003027 124.0
GZD1_k127_4050030_6 TfoX N-terminal domain - - - 0.0000000000000000000000001659 110.0
GZD1_k127_4050030_7 - - - - 0.0000000000000000000000004384 116.0
GZD1_k127_4050030_8 Methyltransferase FkbM domain - - - 0.0000000000000001454 90.0
GZD1_k127_4050030_9 Domain of unknown function (DUF929) - - - 0.00000000002256 75.0
GZD1_k127_4050818_0 AAA-like domain K06915 - - 0.000000000000000000000000000000001663 149.0
GZD1_k127_4050818_1 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000002749 79.0
GZD1_k127_4071784_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 540.0
GZD1_k127_4071784_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 296.0
GZD1_k127_4071784_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000005196 247.0
GZD1_k127_4071784_3 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000003084 156.0
GZD1_k127_4071784_4 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000003014 99.0
GZD1_k127_4071784_5 dUTPase K01520 - 3.6.1.23 0.0000000000003238 79.0
GZD1_k127_4071784_6 - - - - 0.0000000299 60.0
GZD1_k127_4071784_7 Protein of unknown function (DUF1634) - - - 0.000004978 53.0
GZD1_k127_4082215_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 502.0
GZD1_k127_4082215_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 354.0
GZD1_k127_4082215_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01581,K01586,K13747 - 4.1.1.17,4.1.1.20,4.1.1.96 0.0000000000000000000000000001203 118.0
GZD1_k127_4088040_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 619.0
GZD1_k127_4088040_1 Heme copper-type cytochrome quinol K02276,K12132,K15408 - 1.9.3.1,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 610.0
GZD1_k127_4088040_10 - - - - 0.0000000003326 62.0
GZD1_k127_4088040_11 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0007513 51.0
GZD1_k127_4088040_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 443.0
GZD1_k127_4088040_3 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 341.0
GZD1_k127_4088040_4 translation initiation inhibitor, yjgF family K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.0000000000000000000000000000000001958 137.0
GZD1_k127_4088040_5 LAGLIDADG-like domain K07500 - - 0.000000000000000000000000000000001006 141.0
GZD1_k127_4088040_6 COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.000000000000000000000000000002142 128.0
GZD1_k127_4088040_7 sister chromatid segregation - - - 0.00000000000000000000005955 112.0
GZD1_k127_4088040_8 Glycogen debranching enzyme - - - 0.00000000000001018 88.0
GZD1_k127_4088040_9 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000001111 77.0
GZD1_k127_4127347_0 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 290.0
GZD1_k127_4127347_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000009929 92.0
GZD1_k127_4127347_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0003688 44.0
GZD1_k127_4143622_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 2.638e-249 779.0
GZD1_k127_4143622_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 475.0
GZD1_k127_4143622_10 Thermopsin K01385 - 3.4.23.42 0.0000000000000000000000000000000000000000000000000003913 203.0
GZD1_k127_4143622_11 Catalyzes the synthesis of activated sulfate K00860 GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 0.000000000000000000000000000000000000000000000009582 179.0
GZD1_k127_4143622_12 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000003834 138.0
GZD1_k127_4143622_13 amino acid - - - 0.0000000000000000000000000000000001326 151.0
GZD1_k127_4143622_14 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000128 100.0
GZD1_k127_4143622_15 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain - - - 0.000000000000000001343 87.0
GZD1_k127_4143622_2 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 438.0
GZD1_k127_4143622_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 434.0
GZD1_k127_4143622_4 oligoendopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 363.0
GZD1_k127_4143622_5 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 297.0
GZD1_k127_4143622_6 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004288 293.0
GZD1_k127_4143622_7 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003529 257.0
GZD1_k127_4143622_8 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009173 250.0
GZD1_k127_4143622_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000001008 219.0
GZD1_k127_4159054_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01531,K01535 - 3.6.3.2,3.6.3.6 4.642e-312 979.0
GZD1_k127_4159054_1 Protein of unknown function, DUF255 K06888 - - 1.312e-210 675.0
GZD1_k127_4159054_10 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 302.0
GZD1_k127_4159054_11 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 297.0
GZD1_k127_4159054_12 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 289.0
GZD1_k127_4159054_13 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000001088 234.0
GZD1_k127_4159054_14 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000006046 231.0
GZD1_k127_4159054_16 DNA binding protein K06930 - - 0.0000000000000000000000000000000000000008753 159.0
GZD1_k127_4159054_17 - - - - 0.0000000000000000000000000000000000000127 159.0
GZD1_k127_4159054_18 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000005172 131.0
GZD1_k127_4159054_19 transcriptional - - - 0.0000000000000000000000000000002491 131.0
GZD1_k127_4159054_2 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 548.0
GZD1_k127_4159054_20 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000002264 102.0
GZD1_k127_4159054_21 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000005233 98.0
GZD1_k127_4159054_22 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000000005389 104.0
GZD1_k127_4159054_23 Haem-degrading - - - 0.000000000000000002491 90.0
GZD1_k127_4159054_24 RNA methylase - - - 0.00000000000000001201 93.0
GZD1_k127_4159054_25 Domain of unknown function (DU1801) - - - 0.00000000000000003291 87.0
GZD1_k127_4159054_26 - - - - 0.000000000002058 74.0
GZD1_k127_4159054_27 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000008405 57.0
GZD1_k127_4159054_28 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00001019 53.0
GZD1_k127_4159054_29 - - - - 0.00001322 57.0
GZD1_k127_4159054_3 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 551.0
GZD1_k127_4159054_30 Domain of unknown function (DUF4260) - - - 0.00001698 53.0
GZD1_k127_4159054_31 - - - - 0.00004824 51.0
GZD1_k127_4159054_32 - - - - 0.00009953 48.0
GZD1_k127_4159054_4 ERCC4 domain K10896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 443.0
GZD1_k127_4159054_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 421.0
GZD1_k127_4159054_6 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 407.0
GZD1_k127_4159054_7 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 377.0
GZD1_k127_4159054_8 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 368.0
GZD1_k127_4159054_9 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 317.0
GZD1_k127_4180863_0 Helix-hairpin-helix domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 487.0
GZD1_k127_4180863_1 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000163 240.0
GZD1_k127_4180863_2 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000003021 222.0
GZD1_k127_4180863_3 NUDIX domain K01823 - 5.3.3.2 0.0000000000000000000000000000000000000327 152.0
GZD1_k127_4180863_4 Ferrous iron uptake permease, iron-lead transporter - - - 0.00000000000001214 79.0
GZD1_k127_421594_0 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 332.0
GZD1_k127_421594_1 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000006419 149.0
GZD1_k127_421594_2 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.00000000002381 70.0
GZD1_k127_421594_3 integral membrane protein K00728 - 2.4.1.109 0.0001433 53.0
GZD1_k127_4251375_0 Domain of unknown function DUF87 - - - 0.0000000000000000000000000000000000000000000000000000000000000001192 239.0
GZD1_k127_4251375_1 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.000000000000000155 93.0
GZD1_k127_4288696_0 MmgE PrpD family protein K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 462.0
GZD1_k127_4288696_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 366.0
GZD1_k127_4288696_10 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000001127 160.0
GZD1_k127_4288696_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000008692 145.0
GZD1_k127_4288696_12 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000001639 133.0
GZD1_k127_4288696_13 Putative RNA methylase family UPF0020 K07446 - 2.1.1.213 0.0000000000000000000000000000003708 135.0
GZD1_k127_4288696_14 PFAM Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000001881 123.0
GZD1_k127_4288696_15 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000689 112.0
GZD1_k127_4288696_16 - - - - 0.00000000000001992 75.0
GZD1_k127_4288696_17 Belongs to the UPF0201 family K09736 - - 0.00000000000003429 78.0
GZD1_k127_4288696_18 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000001821 61.0
GZD1_k127_4288696_19 SpoVT / AbrB like domain - - - 0.0004482 48.0
GZD1_k127_4288696_2 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 325.0
GZD1_k127_4288696_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 310.0
GZD1_k127_4288696_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004884 281.0
GZD1_k127_4288696_5 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000001022 241.0
GZD1_k127_4288696_6 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000001582 232.0
GZD1_k127_4288696_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000258 213.0
GZD1_k127_4288696_8 AAA domain - - - 0.00000000000000000000000000000000000000000000000000003735 192.0
GZD1_k127_4288696_9 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000002967 186.0
GZD1_k127_4310444_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665,K06883 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 310.0
GZD1_k127_4310444_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000002476 177.0
GZD1_k127_4310444_4 DoxX family K15977,K16937 - 1.8.5.2 0.0000000000001148 78.0
GZD1_k127_4329848_0 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 343.0
GZD1_k127_4329848_1 4Fe-4S binding domain K00338 - 1.6.5.3 0.000000000000000000000000000000006311 146.0
GZD1_k127_4329848_2 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000001183 125.0
GZD1_k127_4329848_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.00000000000000000000000009949 110.0
GZD1_k127_4329848_5 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340 - 1.6.5.3 0.0000000000000000000001323 100.0
GZD1_k127_4329848_6 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit K00342,K22180 - 1.1.98.4,1.6.5.3 0.0000000000000000000002171 105.0
GZD1_k127_4329848_7 3-beta hydroxysteroid dehydrogenase/isomerase family K01710 - 4.2.1.46 0.0008867 52.0
GZD1_k127_4331931_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 413.0
GZD1_k127_4331931_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000002716 186.0
GZD1_k127_4331931_10 - - - - 0.00009891 54.0
GZD1_k127_4331931_2 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000001169 167.0
GZD1_k127_4331931_3 Parallel beta-helix repeats - - - 0.000000000000000000000002355 120.0
GZD1_k127_4331931_4 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000002858 106.0
GZD1_k127_4331931_5 Phosphate uptake regulator K06984 - 2.4.2.54 0.0000000000000000000001319 110.0
GZD1_k127_4331931_6 Protein of unknown function (DUF3052) - - - 0.000000000000000000003568 98.0
GZD1_k127_4331931_7 Protein of unknown function (DUF996) - - - 0.00000000000000000001465 100.0
GZD1_k127_4331931_8 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.000000000000002319 90.0
GZD1_k127_4331931_9 COG1522 Transcriptional regulators - - - 0.00000000003123 66.0
GZD1_k127_4368757_0 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000759 261.0
GZD1_k127_4368757_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000003236 239.0
GZD1_k127_4368757_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000003603 175.0
GZD1_k127_4368757_3 - - - - 0.0000000000000000000000000000003025 129.0
GZD1_k127_4368757_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000004306 89.0
GZD1_k127_4368757_5 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) - - - 0.000000000000002285 85.0
GZD1_k127_4368757_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000004377 55.0
GZD1_k127_4373309_0 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 388.0
GZD1_k127_4373309_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 369.0
GZD1_k127_4373309_2 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 336.0
GZD1_k127_4373309_3 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000001901 205.0
GZD1_k127_4373309_4 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000008753 145.0
GZD1_k127_4373309_5 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000001414 73.0
GZD1_k127_4474_0 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00381 - 1.7.7.1,1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 604.0
GZD1_k127_4474_1 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 308.0
GZD1_k127_4474_10 - - - - 0.0000000000000000000001591 111.0
GZD1_k127_4474_11 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000001293 104.0
GZD1_k127_4474_12 regulatory protein, arsR - - - 0.00000000000000000005535 100.0
GZD1_k127_4474_13 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000002803 104.0
GZD1_k127_4474_14 synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000004864 93.0
GZD1_k127_4474_15 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000008603 80.0
GZD1_k127_4474_17 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000002963 76.0
GZD1_k127_4474_18 SnoaL-like polyketide cyclase - - - 0.000000000006771 73.0
GZD1_k127_4474_19 Domain of unknown function (DUF4349) - - - 0.0000001184 64.0
GZD1_k127_4474_2 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002564 287.0
GZD1_k127_4474_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.00001138 54.0
GZD1_k127_4474_21 PQQ enzyme repeat K00117 - 1.1.5.2 0.00007694 53.0
GZD1_k127_4474_22 Nitrous oxidase accessory protein - - - 0.0007883 52.0
GZD1_k127_4474_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001062 271.0
GZD1_k127_4474_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000002824 226.0
GZD1_k127_4474_5 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.000000000000000000000000000000000000000000000000000000000007419 217.0
GZD1_k127_4474_6 Acetyltransferase (GNAT) domain K00621 - 2.3.1.4 0.000000000000000000000000000000004459 133.0
GZD1_k127_4474_7 -acetyltransferase K03829 - - 0.00000000000000000000000000006386 123.0
GZD1_k127_4474_8 regulator domain protein K01719 - 4.2.1.75 0.00000000000000000000000003776 119.0
GZD1_k127_4474_9 AMP binding - - - 0.00000000000000000000002691 111.0
GZD1_k127_4486834_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 391.0
GZD1_k127_4542679_0 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 365.0
GZD1_k127_4542679_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 337.0
GZD1_k127_4542679_10 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000003284 78.0
GZD1_k127_4542679_11 - - - - 0.00000000008379 67.0
GZD1_k127_4542679_12 PAC2 family K07159 - - 0.00000004982 63.0
GZD1_k127_4542679_2 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000555 263.0
GZD1_k127_4542679_3 AIR synthase related protein domain protein K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005583 250.0
GZD1_k127_4542679_4 PFAM ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000002897 233.0
GZD1_k127_4542679_5 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000001068 170.0
GZD1_k127_4542679_6 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000006005 143.0
GZD1_k127_4542679_7 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000003212 140.0
GZD1_k127_4542679_8 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000001579 103.0
GZD1_k127_4542679_9 PFAM thiamineS protein K03636 - - 0.0000000000003293 79.0
GZD1_k127_4562410_0 Uncharacterised ACR, YkgG family COG1556 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 380.0
GZD1_k127_4562410_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 344.0
GZD1_k127_4562410_2 1-deoxy-D-xylulose-5-phosphate synthase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 297.0
GZD1_k127_4562410_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001544 275.0
GZD1_k127_4562410_4 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000001317 226.0
GZD1_k127_4562410_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000008431 203.0
GZD1_k127_4562410_6 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source K00782 - - 0.000000000000009057 82.0
GZD1_k127_4562410_7 - - - - 0.000000000001515 74.0
GZD1_k127_4565310_0 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000001302 151.0
GZD1_k127_4565310_1 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000008879 157.0
GZD1_k127_4565310_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000006375 143.0
GZD1_k127_4620918_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 293.0
GZD1_k127_4620918_1 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000504 297.0
GZD1_k127_4620918_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002155 294.0
GZD1_k127_4620918_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000008692 161.0
GZD1_k127_4620918_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000001464 110.0
GZD1_k127_4620918_5 PFAM UbiA prenyltransferase family - - - 0.0000000005894 70.0
GZD1_k127_4723578_0 Dehydrogenase - - - 2.523e-203 659.0
GZD1_k127_4723578_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 330.0
GZD1_k127_4723578_2 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006289 282.0
GZD1_k127_4723578_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000207 245.0
GZD1_k127_4723578_4 Branched-chain amino acid ABC transporter, permease protein (BraD-4) K01997 - - 0.000000000000000000000000000000000000000000000000000007267 199.0
GZD1_k127_4723578_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000001159 205.0
GZD1_k127_4723578_6 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000000000000000000005412 122.0
GZD1_k127_4723578_7 PFAM Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000001499 111.0
GZD1_k127_4754628_0 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000001162 230.0
GZD1_k127_4754628_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000222 144.0
GZD1_k127_4754628_2 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000004695 102.0
GZD1_k127_4754628_3 RNA-binding protein contains TRAM domain - - - 0.000000000000001799 82.0
GZD1_k127_4754628_4 NfeD-like C-terminal, partner-binding K07403 - - 0.0006895 47.0
GZD1_k127_4766100_0 Belongs to the complex I 49 kDa subunit family K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 466.0
GZD1_k127_4766100_1 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000001316 206.0
GZD1_k127_4766100_2 NADH ubiquinone oxidoreductase 27 kD subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000002756 148.0
GZD1_k127_4766100_3 ATPase involved in replication control Cdc46 Mcm family K02319,K07500,K10726 - 2.7.7.7 0.000008845 55.0
GZD1_k127_4798785_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 579.0
GZD1_k127_4798785_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 576.0
GZD1_k127_4798785_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000006697 148.0
GZD1_k127_4798785_11 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000003135 90.0
GZD1_k127_4798785_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 437.0
GZD1_k127_4798785_3 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K22169 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 395.0
GZD1_k127_4798785_4 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002774 287.0
GZD1_k127_4798785_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006439 278.0
GZD1_k127_4798785_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000003122 245.0
GZD1_k127_4798785_7 plastoquinone (complex I) K00342,K12137,K12141 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000006212 237.0
GZD1_k127_4798785_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000002624 223.0
GZD1_k127_4798785_9 Domain of unknown function (DU1801) K00784 - 3.1.26.11 0.00000000000000000000000000000000000000005346 155.0
GZD1_k127_4804462_0 RNA-metabolising metallo-beta-lactamase K07041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 447.0
GZD1_k127_4804462_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 352.0
GZD1_k127_4804462_10 - - - - 0.00000002458 59.0
GZD1_k127_4804462_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 334.0
GZD1_k127_4804462_3 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002135 278.0
GZD1_k127_4804462_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000491 256.0
GZD1_k127_4804462_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000005079 225.0
GZD1_k127_4804462_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000001381 218.0
GZD1_k127_4804462_7 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.000000000000000000000000000000000000000000000000000000005123 201.0
GZD1_k127_4804462_8 Cytidylyltransferase-like K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000003057 169.0
GZD1_k127_4804462_9 Ribose 5-phosphate isomerase K01807 - 5.3.1.6 0.000000000000000000000000000000000000000002553 164.0
GZD1_k127_4909249_0 GHMP kinase K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 347.0
GZD1_k127_4909249_1 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004442 284.0
GZD1_k127_4909249_2 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000003531 201.0
GZD1_k127_4909249_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000003864 197.0
GZD1_k127_4909249_4 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000001699 206.0
GZD1_k127_4909249_5 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000006956 144.0
GZD1_k127_4909249_6 D,D-heptose 1,7-bisphosphate phosphatase K03271,K03273 - 3.1.3.82,3.1.3.83,5.3.1.28 0.0000000000000000000000000000000003332 144.0
GZD1_k127_4909249_7 Glycosyl transferase family 21 K00694,K00786 - 2.4.1.12 0.00000000000000000000000000000000167 147.0
GZD1_k127_4909249_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000004307 77.0
GZD1_k127_4909249_9 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid K20946 - - 0.000001895 61.0
GZD1_k127_493374_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 532.0
GZD1_k127_493374_1 Transcriptional regulator, TrmB - - - 0.0000000000000000000000007481 118.0
GZD1_k127_493374_2 PFAM type II secretion system K07333 - - 0.000000000000000000000001132 117.0
GZD1_k127_493374_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000005178 87.0
GZD1_k127_493374_5 Thermopsin - - - 0.000000000000006579 90.0
GZD1_k127_4934848_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 555.0
GZD1_k127_4934848_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 470.0
GZD1_k127_4934848_10 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000001163 108.0
GZD1_k127_4934848_11 prephenate dehydrogenase K04517,K14187 - 1.3.1.12,5.4.99.5 0.0000000006211 71.0
GZD1_k127_4934848_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 393.0
GZD1_k127_4934848_3 Chorismate mutase type II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 326.0
GZD1_k127_4934848_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000005052 247.0
GZD1_k127_4934848_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000003112 169.0
GZD1_k127_4934848_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000001609 161.0
GZD1_k127_4934848_7 PFAM 3-dehydroquinate synthase K11646 - 1.4.1.24 0.00000000000000000000000000000000006663 136.0
GZD1_k127_4934848_8 shikimate kinase activity K00891 - 2.7.1.71 0.000000000000000000000000000000000166 150.0
GZD1_k127_4934848_9 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000006011 113.0
GZD1_k127_500755_0 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 490.0
GZD1_k127_500755_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 333.0
GZD1_k127_500755_10 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000057 108.0
GZD1_k127_500755_11 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 0.000000000000000000001062 104.0
GZD1_k127_500755_12 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000001682 75.0
GZD1_k127_500755_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000005363 57.0
GZD1_k127_500755_2 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 287.0
GZD1_k127_500755_3 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000005137 258.0
GZD1_k127_500755_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000207 252.0
GZD1_k127_500755_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000002073 212.0
GZD1_k127_500755_6 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000001108 166.0
GZD1_k127_500755_7 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.00000000000000000000000000000000007442 141.0
GZD1_k127_500755_8 tail sheath protein K06907 - - 0.00000000000000000000000000000000008808 141.0
GZD1_k127_500755_9 - - - - 0.0000000000000000000000001007 117.0
GZD1_k127_506383_0 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 293.0
GZD1_k127_506383_1 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 289.0
GZD1_k127_506383_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000003423 209.0
GZD1_k127_506383_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000004294 172.0
GZD1_k127_506383_4 Signal transduction protein with CBS domains - - - 0.0000000000000147 80.0
GZD1_k127_506383_5 GDP-mannose mannosyl hydrolase activity - - - 0.0000005519 57.0
GZD1_k127_5069780_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 523.0
GZD1_k127_5069780_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 435.0
GZD1_k127_5069780_10 N-4 methylation of cytosine K00571,K03497 - 2.1.1.72 0.00001872 47.0
GZD1_k127_5069780_11 sequence-specific DNA binding K07108 - - 0.00002353 55.0
GZD1_k127_5069780_12 - - - - 0.00006222 50.0
GZD1_k127_5069780_2 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000001264 251.0
GZD1_k127_5069780_3 protein conserved in archaea - - - 0.00000000000000000000000000000000003205 142.0
GZD1_k127_5069780_4 conserved protein implicated in secretion - - - 0.000000000000000000000000000000002006 137.0
GZD1_k127_5069780_5 Prokaryotic cytochrome b561 K00127,K15878 - - 0.0000000000005776 79.0
GZD1_k127_5069780_6 IclR helix-turn-helix domain - - - 0.0000000000009992 77.0
GZD1_k127_5069780_7 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000137 76.0
GZD1_k127_5069780_8 - - - - 0.000000000131 70.0
GZD1_k127_5069780_9 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.000001013 56.0
GZD1_k127_5070945_0 Lyase K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000002801 247.0
GZD1_k127_5070945_1 - - - - 0.0000000000000000000000000000003274 135.0
GZD1_k127_5070945_2 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000007421 76.0
GZD1_k127_5070945_3 COGs COG3316 Transposase and inactivated derivatives - - - 0.0000001829 55.0
GZD1_k127_5182859_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.477e-196 630.0
GZD1_k127_5182859_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 416.0
GZD1_k127_5182859_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 383.0
GZD1_k127_5182859_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006956 264.0
GZD1_k127_5182859_4 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000000006554 81.0
GZD1_k127_5182859_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL - - - 0.00000000000000008204 83.0
GZD1_k127_5182859_6 CBS domain - - - 0.0000008935 59.0
GZD1_k127_5182859_7 PFAM CBS domain containing protein K04767 - - 0.0001206 54.0
GZD1_k127_5187947_0 Mandelate racemase muconate lactonizing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 451.0
GZD1_k127_5187947_1 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000296 285.0
GZD1_k127_5187947_10 NMT1/THI5 like K02051 - - 0.000006003 59.0
GZD1_k127_5187947_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000545 200.0
GZD1_k127_5187947_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000001588 208.0
GZD1_k127_5187947_4 PQQ-like domain - - - 0.000000000000000000000000000000000009575 154.0
GZD1_k127_5187947_5 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000001721 154.0
GZD1_k127_5187947_6 ABC transporter K02051 - - 0.00000000000000000000000000001073 130.0
GZD1_k127_5187947_7 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000006045 121.0
GZD1_k127_5187947_8 ABC transporter K02051 - - 0.0000000000000000000000124 112.0
GZD1_k127_5187947_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000001457 65.0
GZD1_k127_521657_0 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 404.0
GZD1_k127_521657_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 391.0
GZD1_k127_521657_2 Cytochrome b - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 332.0
GZD1_k127_521657_3 PFAM Rieske 2Fe-2S domain - - - 0.0000000000000000000000000000000000000001899 161.0
GZD1_k127_521657_4 - - - - 0.0000000003842 66.0
GZD1_k127_521657_5 Copper binding proteins, plastocyanin/azurin family - - - 0.000000004403 68.0
GZD1_k127_521657_6 cytochrome b558 566, subunit A - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00001159 57.0
GZD1_k127_521657_7 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0001322 50.0
GZD1_k127_5242596_0 Pfam:KaiC - - - 0.0000000000000000000000000000001688 132.0
GZD1_k127_5242596_1 - - - - 0.0000000000002662 72.0
GZD1_k127_5242596_2 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000006549 78.0
GZD1_k127_5242596_3 Belongs to the UPF0273 family - - - 0.0000000003688 70.0
GZD1_k127_5242596_4 FUN14 family - - - 0.000000003728 63.0
GZD1_k127_5242596_5 Winged helix-turn-helix - - - 0.000004971 55.0
GZD1_k127_5292904_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 432.0
GZD1_k127_5292904_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000001433 192.0
GZD1_k127_5292904_2 NurA - - - 0.00006807 55.0
GZD1_k127_5311408_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 404.0
GZD1_k127_5311408_1 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 305.0
GZD1_k127_5311408_10 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000987 48.0
GZD1_k127_5311408_2 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001289 278.0
GZD1_k127_5311408_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000001954 229.0
GZD1_k127_5311408_4 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000004882 179.0
GZD1_k127_5311408_5 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000000000000000000000002136 166.0
GZD1_k127_5311408_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000007932 124.0
GZD1_k127_5311408_7 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000003407 73.0
GZD1_k127_5311408_8 Belongs to the peptidase M48B family K03799 - - 0.000000001708 69.0
GZD1_k127_5311408_9 negative regulation of transcription, DNA-templated - - - 0.00000003655 62.0
GZD1_k127_5365523_0 Putative RNA methylase family UPF0020 - - - 0.000000000000000000000009932 114.0
GZD1_k127_5365523_1 helicase activity - - - 0.0004557 49.0
GZD1_k127_5395542_0 Xanthine dehydrogenase K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 554.0
GZD1_k127_5395542_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001655 290.0
GZD1_k127_5395542_10 Bacterial extracellular solute-binding protein - - - 0.0007807 45.0
GZD1_k127_5395542_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001029 279.0
GZD1_k127_5395542_3 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002072 250.0
GZD1_k127_5395542_4 PFAM 2Fe-2S -binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000003447 235.0
GZD1_k127_5395542_5 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000161 237.0
GZD1_k127_5395542_6 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000004201 215.0
GZD1_k127_5395542_7 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000003429 92.0
GZD1_k127_5395542_8 iron ion homeostasis K02012 - - 0.000000000000001207 89.0
GZD1_k127_5395542_9 PFAM extracellular solute-binding protein family 1 K02012 - - 0.000000000192 73.0
GZD1_k127_5444516_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 364.0
GZD1_k127_5444516_1 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000000000000001972 218.0
GZD1_k127_5444516_10 Belongs to the PDCD5 family K06875 - - 0.000000000000003879 78.0
GZD1_k127_5444516_11 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000005406 72.0
GZD1_k127_5444516_12 Glyoxalase-like domain - - - 0.0000009166 57.0
GZD1_k127_5444516_13 structural constituent of ribosome K01886,K02924 GO:0000003,GO:0000184,GO:0000956,GO:0002181,GO:0002227,GO:0002251,GO:0002376,GO:0002385,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0007276,GO:0007283,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009617,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0019730,GO:0019731,GO:0019953,GO:0022414,GO:0022625,GO:0022626,GO:0032501,GO:0032504,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042742,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044421,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0045047,GO:0045087,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048232,GO:0048519,GO:0048609,GO:0050789,GO:0050830,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0060255,GO:0061844,GO:0065007,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0098542,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904 6.1.1.18 0.00004342 47.0
GZD1_k127_5444516_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000002556 221.0
GZD1_k127_5444516_3 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000009537 199.0
GZD1_k127_5444516_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000008515 202.0
GZD1_k127_5444516_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000915 182.0
GZD1_k127_5444516_6 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000000000000001355 176.0
GZD1_k127_5444516_7 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000005198 151.0
GZD1_k127_5444516_8 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000002476 93.0
GZD1_k127_5444516_9 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000001231 89.0
GZD1_k127_5464415_0 ATPase associated with various cellular activities, AAA_5 K03924,K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 400.0
GZD1_k127_5464415_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 376.0
GZD1_k127_5464415_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 355.0
GZD1_k127_5464415_3 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002357 280.0
GZD1_k127_5464415_4 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004483 255.0
GZD1_k127_5464415_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000001275 75.0
GZD1_k127_5464415_6 von Willebrand factor (vWF) type A domain - - - 0.0000001587 64.0
GZD1_k127_5464415_7 - - - - 0.000008095 54.0
GZD1_k127_5464415_8 - - - - 0.0004167 46.0
GZD1_k127_5550241_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 536.0
GZD1_k127_5550241_1 methyltransferase K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000001253 221.0
GZD1_k127_5550241_2 sulfhydrylase K01740 - 2.5.1.49 0.000000000000000000000003018 102.0
GZD1_k127_5560019_0 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000535 273.0
GZD1_k127_5560019_1 - - - - 0.0000002148 63.0
GZD1_k127_5586426_0 aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 476.0
GZD1_k127_5586426_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000005645 261.0
GZD1_k127_5586426_2 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000009252 222.0
GZD1_k127_5682265_0 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 414.0
GZD1_k127_5701407_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000002838 214.0
GZD1_k127_5701407_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000001099 187.0
GZD1_k127_5701407_10 Domain of unknown function (DUF929) - - - 0.000000000003314 78.0
GZD1_k127_5701407_11 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.00003313 52.0
GZD1_k127_5701407_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000004576 177.0
GZD1_k127_5701407_3 - - - - 0.00000000000000000000000000000000000000005781 171.0
GZD1_k127_5701407_4 divalent heavy-metal cations transporter K07238 - - 0.00000000000000000000000000000002268 137.0
GZD1_k127_5701407_5 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.0000000000000000000000000000001099 131.0
GZD1_k127_5701407_6 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000004852 138.0
GZD1_k127_5701407_7 PBS lyase HEAT-like repeat K06072 - 1.14.99.29 0.00000000000000000000000002105 117.0
GZD1_k127_5701407_8 Domain of unknown function (DUF4443) - - - 0.000000000000000002162 93.0
GZD1_k127_5701407_9 Hypothetical methyltransferase - - - 0.000000000000000223 86.0
GZD1_k127_5714907_0 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 482.0
GZD1_k127_5714907_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 399.0
GZD1_k127_5714907_10 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001355 245.0
GZD1_k127_5714907_11 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000002101 228.0
GZD1_k127_5714907_12 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000006453 228.0
GZD1_k127_5714907_13 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000001528 178.0
GZD1_k127_5714907_14 Peptidase family M50 - - - 0.0000000000000000000000000000000000000001197 166.0
GZD1_k127_5714907_15 Cytidylyltransferase-like K02201 - 2.7.7.3 0.00000000000000000000000000000000000005273 148.0
GZD1_k127_5714907_16 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.00000000000000000000000000000000004502 148.0
GZD1_k127_5714907_17 Helix-turn-helix domain - - - 0.00000000000000000000000000000000006432 141.0
GZD1_k127_5714907_18 Trm112p-like protein - - - 0.00000000000000000000000007999 110.0
GZD1_k127_5714907_19 Transcriptional regulator PadR-like family K10947 - - 0.0000000000001202 81.0
GZD1_k127_5714907_2 Protein of unknown function (DUF1512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 375.0
GZD1_k127_5714907_20 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000001778 73.0
GZD1_k127_5714907_21 Chromate resistance exported protein - - - 0.0000000151 61.0
GZD1_k127_5714907_22 TOPRIM - - - 0.0000000533 61.0
GZD1_k127_5714907_23 metalloendopeptidase activity - - - 0.0000008636 54.0
GZD1_k127_5714907_24 Copper binding proteins, plastocyanin/azurin family - - - 0.000007876 57.0
GZD1_k127_5714907_25 Cupredoxin-like domain - - - 0.00002085 55.0
GZD1_k127_5714907_26 Cupredoxin-like domain - - - 0.0006684 51.0
GZD1_k127_5714907_3 DNA primase K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 373.0
GZD1_k127_5714907_4 Phenylalanyl-tRNA synthetase alpha subunit K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 371.0
GZD1_k127_5714907_5 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 362.0
GZD1_k127_5714907_6 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 318.0
GZD1_k127_5714907_7 PP-loop family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 304.0
GZD1_k127_5714907_8 PFAM aminoacyl-tRNA synthetase class Ib K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 301.0
GZD1_k127_5714907_9 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000004231 236.0
GZD1_k127_5786854_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1635.0
GZD1_k127_5786854_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 301.0
GZD1_k127_5786854_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003138 260.0
GZD1_k127_5786854_3 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000006771 221.0
GZD1_k127_5786854_4 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000000000000001542 177.0
GZD1_k127_5786854_5 IPT/TIG domain - - - 0.000000000000000000000000000000000000009598 160.0
GZD1_k127_5786854_6 Serine aminopeptidase, S33 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000002713 88.0
GZD1_k127_5786854_7 Belongs to the eukaryotic ribosomal protein eL30 family K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00005166 50.0
GZD1_k127_5824642_0 PFAM Major Facilitator Superfamily - - - 5.012e-210 667.0
GZD1_k127_5824642_1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000002053 144.0
GZD1_k127_5824642_2 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000001141 130.0
GZD1_k127_5824642_3 DHHA1 domain K07463 - - 0.00000000000000000000000000004242 128.0
GZD1_k127_5824642_4 Transcriptional regulator MarR - - - 0.00000000000003396 79.0
GZD1_k127_5824642_5 Thermopsin - - - 0.000000000005389 80.0
GZD1_k127_5824642_6 AAA domain K07028 - - 0.0000000004836 67.0
GZD1_k127_5824642_7 Transcriptional regulator PadR-like family - - - 0.0000105 53.0
GZD1_k127_5835600_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 537.0
GZD1_k127_5835600_1 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 489.0
GZD1_k127_5835600_2 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000002234 127.0
GZD1_k127_5835600_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000003202 111.0
GZD1_k127_5835600_5 - - - - 0.000000000000000003052 90.0
GZD1_k127_5862750_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 608.0
GZD1_k127_5862750_1 PFAM Binding-protein-dependent transport K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 457.0
GZD1_k127_5862750_10 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro K01101 - 3.1.3.41 0.0000000000000000000000000000000001146 143.0
GZD1_k127_5862750_11 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000001187 139.0
GZD1_k127_5862750_12 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000003649 145.0
GZD1_k127_5862750_13 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000057 119.0
GZD1_k127_5862750_14 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.00000000000000000000004995 108.0
GZD1_k127_5862750_15 RNA-binding protein contains TRAM domain - - - 0.000000000000000004031 88.0
GZD1_k127_5862750_16 - - - - 0.000000000000007783 78.0
GZD1_k127_5862750_17 Citrate transporter - - - 0.000000000001899 78.0
GZD1_k127_5862750_18 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000007243 75.0
GZD1_k127_5862750_19 Protein conserved in bacteria K07807 - - 0.0001484 47.0
GZD1_k127_5862750_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 439.0
GZD1_k127_5862750_3 RmlD substrate binding domain K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 384.0
GZD1_k127_5862750_4 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 388.0
GZD1_k127_5862750_5 Phenazine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 300.0
GZD1_k127_5862750_6 PFAM ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 296.0
GZD1_k127_5862750_7 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003963 287.0
GZD1_k127_5862750_8 PFAM MscS Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000661 174.0
GZD1_k127_5862750_9 Transcriptional regulator - - - 0.000000000000000000000000000000000004749 142.0
GZD1_k127_5864714_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 452.0
GZD1_k127_5864714_1 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000005436 164.0
GZD1_k127_5864714_2 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000209 121.0
GZD1_k127_5864714_3 ribosomal protein K02907 - - 0.00000000000000000000000006133 113.0
GZD1_k127_5864714_4 Integral membrane protein DUF106 - - - 0.000009408 54.0
GZD1_k127_5889835_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 380.0
GZD1_k127_5889835_1 cysteinyl-tRNA synthetase K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 345.0
GZD1_k127_5889835_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000002371 156.0
GZD1_k127_5889835_3 Acetyltransferase (GNAT) family - - - 0.000000002153 70.0
GZD1_k127_589055_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 298.0
GZD1_k127_589055_1 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000006554 141.0
GZD1_k127_589055_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000008892 109.0
GZD1_k127_5951466_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 1.435e-316 993.0
GZD1_k127_5951466_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 297.0
GZD1_k127_5951466_2 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000001417 236.0
GZD1_k127_596071_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000002438 216.0
GZD1_k127_596071_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000009527 214.0
GZD1_k127_596071_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000001655 64.0
GZD1_k127_6006285_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 479.0
GZD1_k127_6006285_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 298.0
GZD1_k127_6006285_2 phosphoribosylglycinamide formyltransferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000001242 235.0
GZD1_k127_6006285_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000009131 170.0
GZD1_k127_6006285_4 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.000000000000000000000000000000000004498 144.0
GZD1_k127_6006285_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000001434 87.0
GZD1_k127_6006285_6 PFAM Polysaccharide biosynthesis protein - - - 0.00001807 54.0
GZD1_k127_797227_0 Required both for recombination and for the repair of DNA damage caused by X-rays K04482 GO:0000003,GO:0000018,GO:0000150,GO:0000166,GO:0000217,GO:0000228,GO:0000278,GO:0000280,GO:0000400,GO:0000709,GO:0000722,GO:0000723,GO:0000724,GO:0000725,GO:0000730,GO:0000775,GO:0000785,GO:0000790,GO:0000793,GO:0000794,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006275,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006325,GO:0006342,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007127,GO:0007131,GO:0007530,GO:0007531,GO:0007533,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010212,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0030154,GO:0030491,GO:0030554,GO:0030702,GO:0031297,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032200,GO:0032502,GO:0032505,GO:0032553,GO:0032555,GO:0032559,GO:0033170,GO:0033260,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0035639,GO:0035825,GO:0035861,GO:0036094,GO:0036297,GO:0040029,GO:0042148,GO:0042592,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044786,GO:0044877,GO:0045003,GO:0045005,GO:0045165,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0048285,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051276,GO:0051321,GO:0051716,GO:0060249,GO:0060255,GO:0061806,GO:0061982,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0070013,GO:0070192,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0090734,GO:0090735,GO:0097159,GO:0097367,GO:0098687,GO:0110026,GO:0110027,GO:0140013,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1902298,GO:1902679,GO:1902969,GO:1903046,GO:1903047,GO:1903506,GO:1903507,GO:1905334,GO:1990426,GO:1990505,GO:1990918,GO:2000104,GO:2000112,GO:2000113,GO:2001141 - 0.00002951 55.0
GZD1_k127_797227_1 Winged helix-turn-helix - - - 0.0001212 48.0
GZD1_k127_797227_2 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0003775 52.0
GZD1_k127_834495_0 Peptidase S9 prolyl oligopeptidase active site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 327.0
GZD1_k127_834495_1 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008062 287.0
GZD1_k127_834495_2 TIGRFAM methyltransferase FkbM family - - - 0.000000000000000000000004718 112.0
GZD1_k127_834495_3 Transcriptional regulators - - - 0.0000000000000000000005397 98.0
GZD1_k127_834495_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000004947 68.0
GZD1_k127_834495_5 Glycosyltransferase like family 2 - - - 0.0000001424 63.0
GZD1_k127_834495_6 - - - - 0.00000117 59.0
GZD1_k127_834495_7 nucleotidyltransferase activity - - - 0.0004492 51.0
GZD1_k127_895509_0 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 407.0
GZD1_k127_895509_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000001848 216.0
GZD1_k127_895509_2 COGs COG3888 transcriptional regulator protein - - - 0.000000000000000000000000001105 126.0
GZD1_k127_907072_0 Glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 621.0
GZD1_k127_907072_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 558.0
GZD1_k127_907072_10 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 312.0
GZD1_k127_907072_11 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003911 246.0
GZD1_k127_907072_12 Ribosomal protein L4 K02930 - - 0.0000000000000000000000000000000000000000000000000000002051 203.0
GZD1_k127_907072_13 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.00000000000000000000000000000000000000000000000000001307 192.0
GZD1_k127_907072_14 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000009397 190.0
GZD1_k127_907072_15 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000004121 166.0
GZD1_k127_907072_16 Putative RNA methyltransferase K09142 - - 0.00000000000000000000000000000000000000000005118 173.0
GZD1_k127_907072_17 - - - - 0.0000000000000000000000000000000000000001827 154.0
GZD1_k127_907072_18 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000002394 151.0
GZD1_k127_907072_19 PFAM CBS domain containing protein - - - 0.00000000000000000000000000005206 128.0
GZD1_k127_907072_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 552.0
GZD1_k127_907072_20 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000003443 95.0
GZD1_k127_907072_21 acetolactate synthase, small K01653 - 2.2.1.6 0.000000000000000000003499 105.0
GZD1_k127_907072_22 - - - - 0.0006514 50.0
GZD1_k127_907072_3 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 526.0
GZD1_k127_907072_4 Glutamate synthase alpha subunit domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 505.0
GZD1_k127_907072_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 461.0
GZD1_k127_907072_6 3-isopropylmalate dehydratase activity K01681,K01703,K17749,K20452 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0030312,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.3,4.2.1.33,4.2.1.35,4.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 466.0
GZD1_k127_907072_7 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 378.0
GZD1_k127_907072_8 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 351.0
GZD1_k127_907072_9 ribosomal protein L3 K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 312.0
GZD1_k127_910243_0 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000002495 196.0
GZD1_k127_910243_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000001484 199.0
GZD1_k127_910243_2 - - - - 0.0000000000000000000000000000000000000003257 156.0
GZD1_k127_910243_3 biosynthesis protein QueC K06920 - 6.3.4.20 0.000000000000000000000000000000000001824 148.0
GZD1_k127_910243_4 Transposase - - - 0.000000000004355 72.0
GZD1_k127_910243_5 pyrroloquinoline quinone binding - - - 0.00003138 53.0
GZD1_k127_910243_6 - - - - 0.00027 48.0
GZD1_k127_910937_0 synthetase K01895 - 6.2.1.1 2.501e-288 899.0
GZD1_k127_910937_1 DeoC/LacD family aldolase K08321,K11645 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 367.0
GZD1_k127_910937_10 RNA-binding protein contains TRAM domain - - - 0.00000000000000000005849 93.0
GZD1_k127_910937_11 Membrane protein of 12 TMs K01992,K07087 - - 0.00000000000002693 87.0
GZD1_k127_910937_2 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 364.0
GZD1_k127_910937_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 300.0
GZD1_k127_910937_4 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 286.0
GZD1_k127_910937_5 Oxidoreductase family, C-terminal alpha beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000002469 234.0
GZD1_k127_910937_6 2 iron, 2 sulfur cluster binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000005672 228.0
GZD1_k127_910937_7 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000001455 200.0
GZD1_k127_910937_8 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000001757 135.0
GZD1_k127_910937_9 Ribonuclease HI K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000001685 104.0
GZD1_k127_916609_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 472.0
GZD1_k127_916609_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 310.0
GZD1_k127_916609_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01457,K02433 - 3.5.1.54,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000006407 212.0
GZD1_k127_916609_3 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000006224 205.0
GZD1_k127_916609_4 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000009524 138.0
GZD1_k127_916609_5 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000001266 108.0
GZD1_k127_916609_6 Molybdopterin converting factor, subunit 1. Source PGD - - - 0.000000004361 60.0
GZD1_k127_916609_7 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000125 61.0
GZD1_k127_916609_8 protein conserved in archaea - - - 0.0000006466 55.0
GZD1_k127_916609_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000003005 54.0
GZD1_k127_919182_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 359.0
GZD1_k127_919182_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 336.0
GZD1_k127_919182_2 Belongs to the archaeal-type DHQ synthase family K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000179 244.0
GZD1_k127_919182_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000001722 245.0
GZD1_k127_919182_4 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000167 161.0
GZD1_k127_932437_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 349.0
GZD1_k127_932437_1 lipoate synthase activity K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 336.0
GZD1_k127_932437_2 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000004131 165.0
GZD1_k127_932437_3 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000004721 87.0
GZD1_k127_932437_4 Transcriptional regulator K22206 - - 0.00000000000379 72.0
GZD1_k127_980066_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 433.0
GZD1_k127_980066_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 372.0
GZD1_k127_980066_10 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000002627 235.0
GZD1_k127_980066_11 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000007182 212.0
GZD1_k127_980066_12 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000007807 192.0
GZD1_k127_980066_13 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000009608 186.0
GZD1_k127_980066_14 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000007866 151.0
GZD1_k127_980066_15 - - - - 0.000000000000000000000000000000000003569 144.0
GZD1_k127_980066_16 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000001302 145.0
GZD1_k127_980066_17 - - - - 0.0000000000000000000000000000000001152 148.0
GZD1_k127_980066_18 PFAM multiple antibiotic resistance (MarC)-related K05595 - - 0.000000000000000000000000000008554 128.0
GZD1_k127_980066_19 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000001116 113.0
GZD1_k127_980066_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 351.0
GZD1_k127_980066_20 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000005219 91.0
GZD1_k127_980066_21 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000006515 82.0
GZD1_k127_980066_3 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 308.0
GZD1_k127_980066_4 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 307.0
GZD1_k127_980066_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002708 281.0
GZD1_k127_980066_6 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006175 252.0
GZD1_k127_980066_7 Pterin binding enzyme K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000009932 247.0
GZD1_k127_980066_8 TIGRFAM phosphate ABC transporter K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000002928 248.0
GZD1_k127_980066_9 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000005138 243.0
GZD1_k127_991499_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 514.0
GZD1_k127_991499_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005339 283.0
GZD1_k127_991499_2 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000000000003317 156.0
GZD1_k127_991499_3 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000000000003935 82.0
GZD1_k127_991499_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000001348 77.0