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Overview

ID MAG01567
Name GZD2_bin.57
Sample SMP0041
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Gallionellaceae
Genus DATDDB01
Species
Assembly information
Completeness (%) 78.77
Contamination (%) 2.9
GC content (%) 65.0
N50 (bp) 7,571
Genome size (bp) 2,270,092

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2283

Gene name Description KEGG GOs EC E-value Score Sequence
GZD2_k127_1015293_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1378.0
GZD2_k127_1015293_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 8.659e-229 713.0
GZD2_k127_1015293_2 Oxidoreductase FAD-binding domain protein K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 531.0
GZD2_k127_1015293_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 507.0
GZD2_k127_1015293_4 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 449.0
GZD2_k127_1015293_5 LytTr DNA-binding domain K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 364.0
GZD2_k127_1015293_6 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 329.0
GZD2_k127_1015293_7 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000005462 254.0
GZD2_k127_1028470_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0 1044.0
GZD2_k127_1028470_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 571.0
GZD2_k127_1028470_10 Smr domain - - - 0.0000000000000000000000000000000000000000000000000608 188.0
GZD2_k127_1028470_11 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000003099 180.0
GZD2_k127_1028470_12 NlpC/P60 family K19303 - - 0.0000000000000000000000000000000000000000002812 162.0
GZD2_k127_1028470_14 Peptidase M50 - - - 0.000000000000000000000001328 111.0
GZD2_k127_1028470_15 - - - - 0.0000000000000000004306 91.0
GZD2_k127_1028470_16 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.00000000000002166 73.0
GZD2_k127_1028470_17 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00005825 53.0
GZD2_k127_1028470_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 540.0
GZD2_k127_1028470_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 402.0
GZD2_k127_1028470_4 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 376.0
GZD2_k127_1028470_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 372.0
GZD2_k127_1028470_6 Protein of unknown function (DUF2167) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 349.0
GZD2_k127_1028470_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000341 240.0
GZD2_k127_1028470_8 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000173 206.0
GZD2_k127_1028470_9 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000002803 185.0
GZD2_k127_1031637_0 THUMP K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 610.0
GZD2_k127_1031637_1 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 454.0
GZD2_k127_1031637_2 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 403.0
GZD2_k127_1031637_3 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 359.0
GZD2_k127_1031637_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000001754 249.0
GZD2_k127_1031637_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000005771 211.0
GZD2_k127_1031637_6 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000009501 194.0
GZD2_k127_1031637_7 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.000000000000000000000000000004125 120.0
GZD2_k127_1031637_8 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000007279 90.0
GZD2_k127_104506_0 AcyL-CoA dehydrogenase K06445 - - 1.514e-236 745.0
GZD2_k127_104506_1 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000005059 161.0
GZD2_k127_104506_2 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.00000000000000000000000000000000000003047 147.0
GZD2_k127_104506_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000234 121.0
GZD2_k127_104506_4 AcrB/AcrD/AcrF family K18138 - - 0.0000000000000000000000000002561 116.0
GZD2_k127_1085831_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 417.0
GZD2_k127_1085831_1 repressor - - - 0.00000000000000000000000000000000000001751 152.0
GZD2_k127_1085831_3 ROK family - - - 0.00000000000008377 78.0
GZD2_k127_1086822_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.582e-267 831.0
GZD2_k127_1086822_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.555e-220 693.0
GZD2_k127_1086822_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 432.0
GZD2_k127_1086822_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 393.0
GZD2_k127_1086822_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 364.0
GZD2_k127_1086822_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000004855 87.0
GZD2_k127_111183_0 general secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 293.0
GZD2_k127_111183_1 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000000000000000000000000000000816 181.0
GZD2_k127_111183_2 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000226 78.0
GZD2_k127_1125529_0 ABC transporter transmembrane region K06147 - - 2.953e-275 857.0
GZD2_k127_1125529_1 PAS domain containing protein - - - 1.303e-266 846.0
GZD2_k127_1125529_10 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 341.0
GZD2_k127_1125529_11 mechanosensitive - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 333.0
GZD2_k127_1125529_12 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 322.0
GZD2_k127_1125529_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 305.0
GZD2_k127_1125529_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 299.0
GZD2_k127_1125529_15 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 288.0
GZD2_k127_1125529_16 PFAM Dihaem cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008053 255.0
GZD2_k127_1125529_17 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005396 263.0
GZD2_k127_1125529_18 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000003226 242.0
GZD2_k127_1125529_19 - - - - 0.00000000000000000000000000000000000000000000000000003041 194.0
GZD2_k127_1125529_2 K+ potassium transporter K03549 - - 4.955e-262 820.0
GZD2_k127_1125529_20 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000009163 148.0
GZD2_k127_1125529_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 9.142e-250 786.0
GZD2_k127_1125529_4 pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 5.955e-218 684.0
GZD2_k127_1125529_5 PFAM Thiamine pyrophosphate K00170,K18356 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 544.0
GZD2_k127_1125529_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 483.0
GZD2_k127_1125529_7 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 461.0
GZD2_k127_1125529_8 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 418.0
GZD2_k127_1125529_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 393.0
GZD2_k127_1150587_0 Mate efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 520.0
GZD2_k127_1150587_1 - - - - 0.0000000000000000000006439 104.0
GZD2_k127_1155248_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 481.0
GZD2_k127_1155248_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 358.0
GZD2_k127_1155248_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002854 237.0
GZD2_k127_1155248_3 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000002282 203.0
GZD2_k127_1155248_4 Cupredoxin-like domain - - - 0.00000000000000000002348 95.0
GZD2_k127_1156102_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 5.194e-308 962.0
GZD2_k127_1156102_1 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 321.0
GZD2_k127_1156102_2 Hydrogenase formation hypA family - - - 0.000000000000000000000000000000000000000000000000005432 182.0
GZD2_k127_1163307_0 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 445.0
GZD2_k127_1163307_1 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 361.0
GZD2_k127_1163307_2 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 299.0
GZD2_k127_1163307_3 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000002037 121.0
GZD2_k127_1169939_0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 474.0
GZD2_k127_1169939_1 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 324.0
GZD2_k127_1187664_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 562.0
GZD2_k127_1187664_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
GZD2_k127_1187664_2 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000002675 220.0
GZD2_k127_1187664_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000005492 49.0
GZD2_k127_1190722_0 Diverse 7TM receptor transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 489.0
GZD2_k127_1190722_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 453.0
GZD2_k127_1190722_2 Protein of unknown function (DUF1289) K06938 - - 0.00000000000000003007 83.0
GZD2_k127_120192_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 4.748e-248 769.0
GZD2_k127_120192_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 3.085e-238 743.0
GZD2_k127_120192_2 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 400.0
GZD2_k127_120192_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000001723 219.0
GZD2_k127_120192_4 Outer membrane protein V K07274 - - 0.0000000000000000000000000000000000000000000000000000002161 203.0
GZD2_k127_120192_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000006668 122.0
GZD2_k127_120192_7 Protein of unknown function (DUF3460) - - - 0.000004839 50.0
GZD2_k127_1221975_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 464.0
GZD2_k127_1221975_1 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000001238 181.0
GZD2_k127_1221975_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000001271 168.0
GZD2_k127_1221975_3 Cyd operon protein YbgE (Cyd_oper_YbgE) - - - 0.00000000000000000000000000001437 125.0
GZD2_k127_1246727_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 7.844e-241 762.0
GZD2_k127_1246727_1 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 527.0
GZD2_k127_1246727_2 LysM domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 474.0
GZD2_k127_1246727_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 421.0
GZD2_k127_1246727_4 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001791 252.0
GZD2_k127_1246727_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000002995 173.0
GZD2_k127_1246727_6 - - - - 0.0000000000000000000000000009915 120.0
GZD2_k127_1246727_7 Protein kinase, cAMP-dependent, regulatory, type II, alpha K04739 GO:0000166,GO:0000902,GO:0000904,GO:0001664,GO:0001674,GO:0001932,GO:0001933,GO:0001934,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006469,GO:0006928,GO:0006935,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007596,GO:0007599,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008150,GO:0008603,GO:0009410,GO:0009605,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010720,GO:0014070,GO:0015630,GO:0016020,GO:0016043,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0022607,GO:0023052,GO:0030030,GO:0030104,GO:0030154,GO:0030182,GO:0030234,GO:0030291,GO:0030315,GO:0030534,GO:0030551,GO:0030552,GO:0030554,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031625,GO:0031690,GO:0031698,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032989,GO:0032990,GO:0032991,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035556,GO:0036094,GO:0040011,GO:0042060,GO:0042220,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042330,GO:0042383,GO:0042493,GO:0042585,GO:0042592,GO:0042802,GO:0042803,GO:0042995,GO:0043073,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043279,GO:0043434,GO:0043549,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044853,GO:0045121,GO:0045471,GO:0045475,GO:0045595,GO:0045597,GO:0045787,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046677,GO:0046983,GO:0048148,GO:0048149,GO:0048468,GO:0048471,GO:0048511,GO:0048512,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048871,GO:0048878,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050817,GO:0050878,GO:0050891,GO:0050896,GO:0051018,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051259,GO:0051291,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051446,GO:0051716,GO:0051726,GO:0060255,GO:0060281,GO:0060282,GO:0060284,GO:0060359,GO:0061564,GO:0061695,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072347,GO:0080090,GO:0090068,GO:0097159,GO:0097305,GO:0097332,GO:0097338,GO:0097367,GO:0097485,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:1900193,GO:1900195,GO:1901265,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902911,GO:1903429,GO:1903431,GO:1903538,GO:1904146,GO:1905879,GO:1905881,GO:1990234,GO:2000241,GO:2000243,GO:2000479,GO:2000480 - 0.0004929 49.0
GZD2_k127_12550_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 3.531e-250 775.0
GZD2_k127_12550_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 346.0
GZD2_k127_1284673_0 Sodium/hydrogen exchanger family - - - 1.299e-203 640.0
GZD2_k127_1284673_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 413.0
GZD2_k127_1284673_2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 321.0
GZD2_k127_1284673_3 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.000000000000000000000000000000000000000000008084 169.0
GZD2_k127_1284673_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000001519 62.0
GZD2_k127_1323147_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 334.0
GZD2_k127_1323147_1 deoxyribonucleotide catabolic process K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000002406 232.0
GZD2_k127_1323147_2 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000000006716 212.0
GZD2_k127_1323147_3 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000000000000000004852 194.0
GZD2_k127_1334592_0 Dehydrogenase E1 component K00167,K11381,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 496.0
GZD2_k127_1334592_1 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 349.0
GZD2_k127_1336593_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 414.0
GZD2_k127_1336593_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 314.0
GZD2_k127_1336593_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000000003262 199.0
GZD2_k127_1337450_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 448.0
GZD2_k127_1337450_1 beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 370.0
GZD2_k127_1337450_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 286.0
GZD2_k127_1337450_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000001125 181.0
GZD2_k127_1337450_4 - - - - 0.00000000003037 68.0
GZD2_k127_1337450_5 YaeQ - - - 0.0000001375 53.0
GZD2_k127_135173_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1382.0
GZD2_k127_135173_1 RND efflux system, outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 505.0
GZD2_k127_135173_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 468.0
GZD2_k127_135173_3 Major facilitator Superfamily - - - 0.00007035 49.0
GZD2_k127_136152_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 410.0
GZD2_k127_136152_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 356.0
GZD2_k127_136152_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 326.0
GZD2_k127_136152_3 Belongs to the BolA IbaG family - - - 0.0000000000000000000000001432 121.0
GZD2_k127_136152_4 MlaC protein K07323 - - 0.0000000000000000004961 87.0
GZD2_k127_136152_5 response to antibiotic K07122 - - 0.00000000000008506 77.0
GZD2_k127_1370240_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 381.0
GZD2_k127_1370240_1 PFAM metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 366.0
GZD2_k127_1370240_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 351.0
GZD2_k127_1370240_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 314.0
GZD2_k127_1370240_4 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000002997 153.0
GZD2_k127_1370240_6 Sel1-like repeats. K15474 - - 0.000003302 57.0
GZD2_k127_1389258_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0 1100.0
GZD2_k127_1389258_1 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 350.0
GZD2_k127_1389258_2 NUDIX domain - - - 0.0000000000000000000000000000000000000000000004056 168.0
GZD2_k127_1389258_3 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000002032 137.0
GZD2_k127_1389258_4 Copper binding periplasmic protein CusF - - - 0.00000000000000000000000000002246 124.0
GZD2_k127_1389258_5 Redoxin K03564 - 1.11.1.15 0.0000000002945 62.0
GZD2_k127_1435657_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 6.557e-245 759.0
GZD2_k127_1435657_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 586.0
GZD2_k127_1435657_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000000231 138.0
GZD2_k127_1435657_11 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000001818 140.0
GZD2_k127_1435657_12 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000004905 82.0
GZD2_k127_1435657_13 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000003174 66.0
GZD2_k127_1435657_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 583.0
GZD2_k127_1435657_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 487.0
GZD2_k127_1435657_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 409.0
GZD2_k127_1435657_5 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 401.0
GZD2_k127_1435657_6 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 401.0
GZD2_k127_1435657_7 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 389.0
GZD2_k127_1435657_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 342.0
GZD2_k127_1435657_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 315.0
GZD2_k127_1437331_0 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 510.0
GZD2_k127_1437331_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 365.0
GZD2_k127_1437331_2 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 336.0
GZD2_k127_1437331_3 dehydratase - - - 0.000000000000000000000000000000000000000000000000005316 187.0
GZD2_k127_1437331_4 membrane - - - 0.00000000000000000000000000000000000000000002978 173.0
GZD2_k127_1437331_5 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000000000004798 141.0
GZD2_k127_1437331_6 FabA-like domain - - - 0.0000000000000000004033 97.0
GZD2_k127_1437331_7 Beta-ketoacyl synthase, N-terminal domain - - - 0.0005913 44.0
GZD2_k127_1488676_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.822e-277 859.0
GZD2_k127_1488676_1 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 424.0
GZD2_k127_1488676_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000002957 169.0
GZD2_k127_1488676_3 Protein of unknown function (DUF3426) - - - 0.000000000000000006324 86.0
GZD2_k127_1495129_0 phosphorylase K00688 - 2.4.1.1 3.043e-287 899.0
GZD2_k127_1495129_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 562.0
GZD2_k127_1495129_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 471.0
GZD2_k127_1495129_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 384.0
GZD2_k127_1495129_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 287.0
GZD2_k127_1495129_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002092 277.0
GZD2_k127_1495129_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000001232 243.0
GZD2_k127_1495129_7 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000000000000000000000000000000000000000001115 170.0
GZD2_k127_1495129_8 - - - - 0.000000000000000000000000000009592 124.0
GZD2_k127_1534611_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 446.0
GZD2_k127_1534611_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 343.0
GZD2_k127_1539048_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 562.0
GZD2_k127_1539048_1 PFAM AICARFT IMPCHase bienzyme formylation region K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 520.0
GZD2_k127_1539048_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 336.0
GZD2_k127_1539048_3 Bacterial regulatory protein, Fis family K03557 - - 0.000000000000000000000000000000003021 130.0
GZD2_k127_1556073_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.994e-213 666.0
GZD2_k127_1556073_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 550.0
GZD2_k127_1556073_2 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 464.0
GZD2_k127_1556073_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 391.0
GZD2_k127_1556073_4 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 364.0
GZD2_k127_1556073_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000001044 249.0
GZD2_k127_1556073_6 Protein of unknown function (DUF494) K03747 - - 0.000000000000000000000000000000000000000000000000000000002811 204.0
GZD2_k127_1556655_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
GZD2_k127_1556655_1 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 311.0
GZD2_k127_1556655_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000002253 223.0
GZD2_k127_1556655_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K03387 - - 0.0000000000000000000005407 100.0
GZD2_k127_1566019_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.326e-247 768.0
GZD2_k127_1566019_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.15e-224 703.0
GZD2_k127_1566019_10 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 349.0
GZD2_k127_1566019_11 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 344.0
GZD2_k127_1566019_12 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000003656 192.0
GZD2_k127_1566019_13 phenylacetate-CoA ligase activity - - - 0.0000000000000000000000000000000000000000000000000005912 196.0
GZD2_k127_1566019_14 PFAM HopJ type III effector protein - - - 0.0000000000000000000000000000000000000000000000009391 177.0
GZD2_k127_1566019_15 OmpA family K03640 - - 0.00000000000000000000000000000000000000000000001298 176.0
GZD2_k127_1566019_16 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000002685 176.0
GZD2_k127_1566019_17 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000005418 169.0
GZD2_k127_1566019_18 TolA C-terminal K03646 - - 0.0000000000000000000000000000000000005081 149.0
GZD2_k127_1566019_19 acr, cog1430 K09005 - - 0.0000000000000000000000000000000003913 136.0
GZD2_k127_1566019_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 2.626e-216 677.0
GZD2_k127_1566019_20 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000001068 129.0
GZD2_k127_1566019_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 589.0
GZD2_k127_1566019_4 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 563.0
GZD2_k127_1566019_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 488.0
GZD2_k127_1566019_6 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 478.0
GZD2_k127_1566019_7 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 414.0
GZD2_k127_1566019_8 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 361.0
GZD2_k127_1566019_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 353.0
GZD2_k127_1568540_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1375.0
GZD2_k127_1568540_1 ATPases associated with a variety of cellular activities - - - 0.0 1334.0
GZD2_k127_1568540_10 WD40 domain protein beta Propeller K03641 - - 0.000000000000000000000003602 116.0
GZD2_k127_1568540_11 - - - - 0.000006125 60.0
GZD2_k127_1568540_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.474e-217 680.0
GZD2_k127_1568540_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 621.0
GZD2_k127_1568540_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 583.0
GZD2_k127_1568540_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 488.0
GZD2_k127_1568540_6 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 479.0
GZD2_k127_1568540_7 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 337.0
GZD2_k127_1568540_8 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000001193 129.0
GZD2_k127_1568540_9 Zinc-finger domain - - - 0.00000000000000000000000005318 109.0
GZD2_k127_15926_0 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 473.0
GZD2_k127_15926_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.00000000000000000000000006582 108.0
GZD2_k127_15926_2 OmpA-like transmembrane domain K03286 - - 0.0006156 49.0
GZD2_k127_1652958_0 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 530.0
GZD2_k127_1652958_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 318.0
GZD2_k127_1652958_2 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 288.0
GZD2_k127_1652958_3 protein with protein kinase and helix-hairpin-helix DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002841 276.0
GZD2_k127_1652958_4 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002964 231.0
GZD2_k127_1652958_5 Protein phosphatase 2C - - - 0.000000000000000000000000000000000000000000000000000000001 210.0
GZD2_k127_1652958_6 probably involved in intracellular septation K06190 - - 0.000001561 59.0
GZD2_k127_1654993_0 DHH family K07462 - - 1.934e-262 820.0
GZD2_k127_1654993_1 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 4.274e-230 719.0
GZD2_k127_1654993_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 525.0
GZD2_k127_1654993_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 375.0
GZD2_k127_1654993_4 - - - - 0.0000000000000000000000000000000000000000000000001755 184.0
GZD2_k127_1654993_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000004362 147.0
GZD2_k127_1657860_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 6.657e-306 952.0
GZD2_k127_1657860_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 1.587e-239 747.0
GZD2_k127_1657860_10 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
GZD2_k127_1657860_11 Frataxin-like domain K06202 - - 0.0000000000000000000000000000000423 126.0
GZD2_k127_1657860_12 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000000000000000000000000000001945 127.0
GZD2_k127_1657860_2 Nitronate monooxygenase K00459 - 1.13.12.16 2.322e-228 711.0
GZD2_k127_1657860_3 AsmA family K07289 - - 1.108e-220 706.0
GZD2_k127_1657860_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 579.0
GZD2_k127_1657860_5 endonuclease III K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 497.0
GZD2_k127_1657860_6 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 391.0
GZD2_k127_1657860_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 388.0
GZD2_k127_1657860_8 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 327.0
GZD2_k127_1657860_9 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 290.0
GZD2_k127_1658669_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 563.0
GZD2_k127_1658669_1 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 464.0
GZD2_k127_1658669_2 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000002083 173.0
GZD2_k127_1674737_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1960.0
GZD2_k127_1674737_1 Glycosyltransferase like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001598 266.0
GZD2_k127_1674737_2 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000751 214.0
GZD2_k127_1674737_3 Glycosyltransferase like family - - - 0.000000000000000000000000000000000000000000000000000000000001272 224.0
GZD2_k127_1674737_4 - - - - 0.00000000000000000000000166 108.0
GZD2_k127_1679291_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 2.655e-235 743.0
GZD2_k127_1679291_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000008395 228.0
GZD2_k127_1679291_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000003011 208.0
GZD2_k127_1679291_3 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000004332 159.0
GZD2_k127_1679291_4 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000001579 153.0
GZD2_k127_1679291_5 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000003092 134.0
GZD2_k127_1684404_0 AcrB/AcrD/AcrF family - - - 0.0 1349.0
GZD2_k127_1684404_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K05962 - 2.7.13.1 0.00000000000000000000000000000000000000009213 154.0
GZD2_k127_16911_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 374.0
GZD2_k127_16911_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000001916 216.0
GZD2_k127_16911_2 Histidine kinase K11617 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000028 204.0
GZD2_k127_16911_3 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000001799 129.0
GZD2_k127_1695066_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 6.959e-198 627.0
GZD2_k127_1695066_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 475.0
GZD2_k127_1695066_2 P-loop ATPase protein family K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 422.0
GZD2_k127_1695066_3 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 385.0
GZD2_k127_1695066_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 319.0
GZD2_k127_1695066_5 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000000000000001011 241.0
GZD2_k127_1695066_6 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000002271 229.0
GZD2_k127_1695066_7 PFAM sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000000000000349 156.0
GZD2_k127_1695066_8 translation initiation factor activity - - - 0.00000000000000000000000000000002829 128.0
GZD2_k127_1695066_9 NusG domain II - - - 0.0000000000001149 75.0
GZD2_k127_1702012_0 Putative diguanylate phosphodiesterase - - - 5.895e-230 722.0
GZD2_k127_1702012_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000003597 259.0
GZD2_k127_1702012_2 response regulator - - - 0.00000000000000000000000002563 116.0
GZD2_k127_1702012_3 - - - - 0.00000000000009435 75.0
GZD2_k127_1703880_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 565.0
GZD2_k127_1703880_1 NADH flavin K09461 - 1.14.13.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 520.0
GZD2_k127_1703880_10 MlaD protein K02067 - - 0.00000000000000000000000000000000007145 145.0
GZD2_k127_1703880_11 dUTPase - - - 0.000000000001053 79.0
GZD2_k127_1703880_12 ATPase activity K02065 - - 0.0000003909 60.0
GZD2_k127_1703880_2 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 526.0
GZD2_k127_1703880_3 Starch synthase catalytic domain K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 328.0
GZD2_k127_1703880_4 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
GZD2_k127_1703880_5 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000004925 234.0
GZD2_k127_1703880_6 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001457 239.0
GZD2_k127_1703880_7 - - - - 0.00000000000000000000000000000000000000000000000000000000003018 209.0
GZD2_k127_1703880_8 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000000008324 184.0
GZD2_k127_1703880_9 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000718 173.0
GZD2_k127_1711731_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1679.0
GZD2_k127_1711731_1 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 596.0
GZD2_k127_1711731_2 DSBA Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006671 264.0
GZD2_k127_1711731_3 - - - - 0.00000000000000000000009474 111.0
GZD2_k127_1716353_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1134.0
GZD2_k127_1716353_1 Polysulphide reductase, NrfD K00185 - - 3.639e-290 892.0
GZD2_k127_1716353_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002074 261.0
GZD2_k127_1716353_11 Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000006778 162.0
GZD2_k127_1716353_12 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000003542 124.0
GZD2_k127_1716353_13 Frataxin-like domain K06202 - - 0.00000000000000005488 84.0
GZD2_k127_1716353_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 599.0
GZD2_k127_1716353_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 537.0
GZD2_k127_1716353_4 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 513.0
GZD2_k127_1716353_5 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 382.0
GZD2_k127_1716353_6 Glutathione S-transferase, C-terminal domain K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 367.0
GZD2_k127_1716353_7 Belongs to the GbsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 354.0
GZD2_k127_1716353_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 319.0
GZD2_k127_1716353_9 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 286.0
GZD2_k127_1718851_0 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 443.0
GZD2_k127_1718851_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 402.0
GZD2_k127_1718851_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 380.0
GZD2_k127_173125_0 L-fucose isomerase, C-terminal domain - - - 7.481e-232 728.0
GZD2_k127_173125_1 PFAM Carbohydrate kinase K00853 - 2.7.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 539.0
GZD2_k127_173125_2 - - - - 0.00000000000000006384 83.0
GZD2_k127_175845_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365,K05366 - 2.4.1.129,3.4.16.4 0.0 1135.0
GZD2_k127_175845_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 423.0
GZD2_k127_175845_2 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000001202 213.0
GZD2_k127_175845_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000373 152.0
GZD2_k127_175845_4 COG2199 FOG GGDEF domain K13590 - 2.7.7.65 0.0000000000000000000000000000000000003877 154.0
GZD2_k127_175845_5 photosynthesis K12132,K20543 - 2.7.11.1 0.0000000000000000000000000000000000006117 150.0
GZD2_k127_175845_6 KTSC domain - - - 0.000000000000000000000000000000002031 131.0
GZD2_k127_175845_7 Domain of unknown function (DUF4389) - - - 0.00000000000000008984 88.0
GZD2_k127_175845_8 - - - - 0.00000000000004392 76.0
GZD2_k127_1764096_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1497.0
GZD2_k127_1764096_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 545.0
GZD2_k127_1764096_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000002994 78.0
GZD2_k127_1764096_3 - - - - 0.00000002403 55.0
GZD2_k127_1767113_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1459.0
GZD2_k127_1767113_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 8.719e-229 714.0
GZD2_k127_1767113_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 318.0
GZD2_k127_1767113_11 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 311.0
GZD2_k127_1767113_12 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 304.0
GZD2_k127_1767113_13 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008533 241.0
GZD2_k127_1767113_14 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000001906 244.0
GZD2_k127_1767113_15 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000000000000747 183.0
GZD2_k127_1767113_16 Protein of unknown function (DUF721) - - - 0.000000000000000002258 90.0
GZD2_k127_1767113_17 GTP binding K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000001912 53.0
GZD2_k127_1767113_19 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00006735 46.0
GZD2_k127_1767113_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 2.891e-207 649.0
GZD2_k127_1767113_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 574.0
GZD2_k127_1767113_4 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 583.0
GZD2_k127_1767113_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 552.0
GZD2_k127_1767113_6 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 507.0
GZD2_k127_1767113_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 493.0
GZD2_k127_1767113_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 426.0
GZD2_k127_1767113_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 337.0
GZD2_k127_1775242_0 extracellular alpha-helical protein K06894 - - 0.0 1810.0
GZD2_k127_1775242_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.00000000000000004331 86.0
GZD2_k127_1789631_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1098.0
GZD2_k127_1789631_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.861e-277 859.0
GZD2_k127_1789631_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 299.0
GZD2_k127_1789631_11 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.00000000000000000000000000000000000000000000000004099 183.0
GZD2_k127_1789631_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000001156 161.0
GZD2_k127_1789631_13 chlorophyll binding - - - 0.00000000000000000000000000000000133 130.0
GZD2_k127_1789631_14 Domain of unknown function (DUF4845) - - - 0.00000000000000000000001127 106.0
GZD2_k127_1789631_15 - - - - 0.00000000000000000000004123 109.0
GZD2_k127_1789631_16 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000000000000000006756 101.0
GZD2_k127_1789631_2 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 9.136e-194 619.0
GZD2_k127_1789631_3 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 502.0
GZD2_k127_1789631_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 460.0
GZD2_k127_1789631_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 426.0
GZD2_k127_1789631_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 368.0
GZD2_k127_1789631_7 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 357.0
GZD2_k127_1789631_8 TIGRFAM RNA polymerase sigma factor RpoE K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 347.0
GZD2_k127_1789631_9 MucB/RseB C-terminal domain K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 323.0
GZD2_k127_1795017_0 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005184 267.0
GZD2_k127_1795017_1 HAF family - - - 0.0000000000000000000000000000000000000000000000008817 193.0
GZD2_k127_1820740_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.138e-286 884.0
GZD2_k127_1820740_1 ATP synthase (C/AC39) subunit K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 423.0
GZD2_k127_1820740_2 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 387.0
GZD2_k127_1820740_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 353.0
GZD2_k127_1820740_4 V-type ATPase 116kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000002892 176.0
GZD2_k127_1820740_5 maturation - - - 0.0000000000000000000000000000000000000000001061 164.0
GZD2_k127_1820740_6 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000101 136.0
GZD2_k127_1820740_7 - - - - 0.000000000000000000000000006602 113.0
GZD2_k127_1841753_0 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 578.0
GZD2_k127_1841753_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 584.0
GZD2_k127_1841753_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 404.0
GZD2_k127_1841753_3 Cytochrome c K19713 - 1.8.2.2 0.00000000000000000000000000000000001697 141.0
GZD2_k127_1841753_4 PFAM ABC transporter related K01990,K09695 - - 0.000000000000000000000000008056 110.0
GZD2_k127_1855183_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.397e-226 709.0
GZD2_k127_1855183_1 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 460.0
GZD2_k127_1855183_2 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 406.0
GZD2_k127_1855183_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008562 243.0
GZD2_k127_1855183_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000001351 215.0
GZD2_k127_1855183_5 - - - - 0.0000000000000000000000002472 109.0
GZD2_k127_1856404_0 CoA-binding domain protein K09181 - - 0.0 1392.0
GZD2_k127_1856404_1 PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 1.528e-236 736.0
GZD2_k127_1856404_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 3.808e-203 632.0
GZD2_k127_1856404_3 PFAM D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 527.0
GZD2_k127_1856404_4 PFAM AICARFT IMPCHase bienzyme formylation region K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 516.0
GZD2_k127_1856404_5 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 478.0
GZD2_k127_1856404_6 PFAM ABC transporter related K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008527 402.0
GZD2_k127_1856404_7 Ferritin-like domain K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 286.0
GZD2_k127_1856404_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006079 274.0
GZD2_k127_1859741_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 1.314e-308 954.0
GZD2_k127_1859741_1 CHASE2 K01768 - 4.6.1.1 8.017e-198 633.0
GZD2_k127_1859741_2 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 385.0
GZD2_k127_1864041_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0 1125.0
GZD2_k127_1864041_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1046.0
GZD2_k127_1864041_10 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000001249 140.0
GZD2_k127_1864041_2 4 iron, 4 sulfur cluster binding - - - 1.908e-229 722.0
GZD2_k127_1864041_3 PFAM glycine cleavage T protein (aminomethyl transferase) K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 412.0
GZD2_k127_1864041_4 CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 391.0
GZD2_k127_1864041_5 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002843 282.0
GZD2_k127_1864041_6 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003015 264.0
GZD2_k127_1864041_7 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001467 256.0
GZD2_k127_1864041_8 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000001337 236.0
GZD2_k127_1864041_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002764 216.0
GZD2_k127_1883788_0 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 447.0
GZD2_k127_1883788_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004331 271.0
GZD2_k127_1883788_2 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000000000000000000000000004589 226.0
GZD2_k127_1883788_3 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.00000000000000000000000000000000000000000000000000000009378 196.0
GZD2_k127_1883788_4 Iron-sulphur cluster assembly - - - 0.00000000000000000000000000002886 118.0
GZD2_k127_1888127_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 5.158e-309 960.0
GZD2_k127_1888127_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 357.0
GZD2_k127_1888127_2 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002719 253.0
GZD2_k127_1888127_3 TIGRFAM Cytochrome o ubiquinol oxidase, subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
GZD2_k127_1888127_4 TIGRFAM Cytochrome o ubiquinol oxidase subunit IV K02300 - - 0.000000000000000000000000924 106.0
GZD2_k127_1907607_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 7.519e-227 721.0
GZD2_k127_1907607_1 [2Fe-2S] binding domain K00256,K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000004502 218.0
GZD2_k127_1910453_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 3.843e-290 900.0
GZD2_k127_1910453_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 7.497e-271 846.0
GZD2_k127_1910453_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.924e-263 824.0
GZD2_k127_1910453_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 551.0
GZD2_k127_1943456_0 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000005551 252.0
GZD2_k127_1943456_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003022 219.0
GZD2_k127_1948494_0 Domain of unknown function (DUF4132) - - - 3.061e-237 775.0
GZD2_k127_1948494_1 protein containing a von Willebrand factor type A (vWA) domain - - - 2.073e-220 709.0
GZD2_k127_1948494_2 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 544.0
GZD2_k127_1948494_3 VWA domain containing CoxE-like protein - - - 0.0000000000000000000000000000000000000000000008313 174.0
GZD2_k127_1968255_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 3.294e-219 696.0
GZD2_k127_1968255_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 590.0
GZD2_k127_1968255_2 virion core protein (lumpy skin disease virus) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 383.0
GZD2_k127_1968255_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 379.0
GZD2_k127_1968255_4 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 295.0
GZD2_k127_1968255_5 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000001799 220.0
GZD2_k127_1968255_6 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000003884 139.0
GZD2_k127_1968255_7 Domain of Unknown Function (DUF350) - - - 0.0000000000000001699 81.0
GZD2_k127_1980065_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 1.716e-219 688.0
GZD2_k127_1980065_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 1.621e-203 640.0
GZD2_k127_1980065_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006193 228.0
GZD2_k127_1980065_11 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000001429 184.0
GZD2_k127_1980065_12 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000000009122 154.0
GZD2_k127_1980065_13 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000007431 149.0
GZD2_k127_1980065_14 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000005278 107.0
GZD2_k127_1980065_16 TIGRFAM clan AA aspartic protease, TIGR02281 family K06985 - - 0.000000004046 67.0
GZD2_k127_1980065_17 gag-polyprotein putative aspartyl protease K06985 - - 0.000402 50.0
GZD2_k127_1980065_2 PFAM AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 582.0
GZD2_k127_1980065_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 396.0
GZD2_k127_1980065_4 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 359.0
GZD2_k127_1980065_5 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 362.0
GZD2_k127_1980065_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 316.0
GZD2_k127_1980065_7 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 310.0
GZD2_k127_1980065_8 Bacterial dnaA protein K10763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001449 293.0
GZD2_k127_1980065_9 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000284 246.0
GZD2_k127_2001399_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 569.0
GZD2_k127_2001399_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006118 276.0
GZD2_k127_20161_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 459.0
GZD2_k127_20161_1 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 368.0
GZD2_k127_20161_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000001253 221.0
GZD2_k127_20161_3 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000008206 214.0
GZD2_k127_202604_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.904e-254 792.0
GZD2_k127_202604_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 608.0
GZD2_k127_202604_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 401.0
GZD2_k127_202779_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 537.0
GZD2_k127_202779_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 504.0
GZD2_k127_202779_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 340.0
GZD2_k127_2029756_0 Sugar (and other) transporter - - - 1.193e-289 897.0
GZD2_k127_2029756_1 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 619.0
GZD2_k127_2029756_10 protein conserved in bacteria containing a divergent form of TPR repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002595 283.0
GZD2_k127_2029756_11 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006289 267.0
GZD2_k127_2029756_12 - - - - 0.0000000000000000000000000000000000007189 150.0
GZD2_k127_2029756_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 530.0
GZD2_k127_2029756_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 514.0
GZD2_k127_2029756_4 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 471.0
GZD2_k127_2029756_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 409.0
GZD2_k127_2029756_6 Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 395.0
GZD2_k127_2029756_7 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 399.0
GZD2_k127_2029756_8 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 366.0
GZD2_k127_2029756_9 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 318.0
GZD2_k127_2055002_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.636e-208 649.0
GZD2_k127_2055002_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 489.0
GZD2_k127_2055002_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001322 276.0
GZD2_k127_2062633_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 463.0
GZD2_k127_2062633_1 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 363.0
GZD2_k127_2062633_2 Two component transcriptional regulator, winged K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002037 265.0
GZD2_k127_2132964_0 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 615.0
GZD2_k127_2132964_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 486.0
GZD2_k127_2132964_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 376.0
GZD2_k127_2132964_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 268.0
GZD2_k127_2132964_4 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000001605 185.0
GZD2_k127_2132964_5 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000457 112.0
GZD2_k127_2132964_6 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000001193 85.0
GZD2_k127_2149594_0 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 431.0
GZD2_k127_2149594_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 316.0
GZD2_k127_2149594_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 313.0
GZD2_k127_2149594_3 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000001604 92.0
GZD2_k127_2149594_4 ankyrin repeat K15502 - - 0.0000000000000000421 89.0
GZD2_k127_2157056_0 PFAM DEAD DEAH box helicase domain protein K05591 GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 1.425e-283 874.0
GZD2_k127_2157056_1 SMART adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 512.0
GZD2_k127_2157056_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 417.0
GZD2_k127_2157056_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 329.0
GZD2_k127_2157056_4 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 291.0
GZD2_k127_2157056_5 TIGRFAM PAS sensor protein - - - 0.00000000000002941 86.0
GZD2_k127_2162664_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1048.0
GZD2_k127_2162664_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 413.0
GZD2_k127_2162664_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001007 273.0
GZD2_k127_2162664_3 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002292 241.0
GZD2_k127_2173344_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 586.0
GZD2_k127_2173344_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000007151 177.0
GZD2_k127_2176338_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 583.0
GZD2_k127_2176338_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 520.0
GZD2_k127_2176338_2 CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 410.0
GZD2_k127_2176338_3 helix_turn_helix, cAMP Regulatory protein - - - 0.00001705 56.0
GZD2_k127_217978_0 AAA domain K02224 - 6.3.5.11,6.3.5.9 5.54e-229 716.0
GZD2_k127_217978_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 6.492e-227 707.0
GZD2_k127_217978_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 2.379e-215 674.0
GZD2_k127_217978_3 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 569.0
GZD2_k127_217978_4 Glycosyl transferase - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 372.0
GZD2_k127_217978_5 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 355.0
GZD2_k127_217978_6 - - - - 0.0000000000000000000000000000000000000001513 153.0
GZD2_k127_217978_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000003281 76.0
GZD2_k127_2203764_0 PFAM ABC transporter related K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 406.0
GZD2_k127_2203764_1 Domain of unknown function (DUF4124) - - - 0.0000000000001079 76.0
GZD2_k127_2203764_2 SlyX K03745 - - 0.00000000002528 64.0
GZD2_k127_222416_0 Heat shock 70 kDa protein K04043 - - 6.583e-300 930.0
GZD2_k127_222416_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 466.0
GZD2_k127_222416_2 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 289.0
GZD2_k127_222416_3 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008137 280.0
GZD2_k127_2244909_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1669.0
GZD2_k127_2244909_1 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 390.0
GZD2_k127_2244909_2 - - - - 0.00000000000000000000000000000000000000000000000000000000001973 208.0
GZD2_k127_2249505_0 Putative diguanylate phosphodiesterase - - - 2.495e-216 688.0
GZD2_k127_2249505_1 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 594.0
GZD2_k127_2249505_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000004521 223.0
GZD2_k127_2249505_3 response regulator - - - 0.00000000000000000000000000002886 118.0
GZD2_k127_2265996_0 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 308.0
GZD2_k127_2265996_1 ATP-binding protein K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 287.0
GZD2_k127_2265996_2 Transcriptional regulator K02019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000983 275.0
GZD2_k127_2265996_3 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001477 262.0
GZD2_k127_2265996_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000524 174.0
GZD2_k127_2265996_5 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02019 - - 0.00000000000000000000000000000000000001071 149.0
GZD2_k127_229943_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 6.995e-235 731.0
GZD2_k127_229943_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 466.0
GZD2_k127_2309185_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 554.0
GZD2_k127_2309185_1 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 443.0
GZD2_k127_2309185_2 membrane - - - 0.00000000000000000000000000000000000000000000001343 174.0
GZD2_k127_2330503_0 Protein of unknown function, DUF255 K06888 - - 1.012e-207 657.0
GZD2_k127_2330503_1 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 456.0
GZD2_k127_2330503_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001272 262.0
GZD2_k127_2361632_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001101 280.0
GZD2_k127_2361632_1 SMART Cold shock protein K03704 - - 0.00000000000000000000000000001643 120.0
GZD2_k127_2361632_2 response regulator K13041 - - 0.000000000000005608 85.0
GZD2_k127_2361632_3 - - - - 0.0000000226 61.0
GZD2_k127_2365258_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 594.0
GZD2_k127_2365258_1 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 295.0
GZD2_k127_2365258_2 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001672 286.0
GZD2_k127_2365258_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000004072 201.0
GZD2_k127_2365258_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000007416 193.0
GZD2_k127_2365258_6 Protein of unknown function (DUF2288) - - - 0.0000000000000000000000000000000000002979 151.0
GZD2_k127_24081_0 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 476.0
GZD2_k127_24081_1 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001422 246.0
GZD2_k127_2411873_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 576.0
GZD2_k127_2411873_1 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 467.0
GZD2_k127_2411873_2 Transcriptional - - - 0.0000000000000000000000000001054 121.0
GZD2_k127_2411873_3 Peptidase S24-like - - - 0.0000000000000005364 80.0
GZD2_k127_2415513_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 548.0
GZD2_k127_2415513_1 Transcriptional regulator K18304 - - 0.0000000000000000000000000000000000000000000000000000000009309 209.0
GZD2_k127_2415513_2 General secretion pathway K02462 - - 0.00000000000000000000000000000000104 137.0
GZD2_k127_2415513_4 sequence-specific DNA binding - - - 0.00000000000000001245 85.0
GZD2_k127_2416207_0 PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal K01621 GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 0.0 1416.0
GZD2_k127_2416207_1 Amino acid permease - - - 4.883e-258 810.0
GZD2_k127_2416207_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 564.0
GZD2_k127_2416207_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 458.0
GZD2_k127_2416207_4 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000004011 151.0
GZD2_k127_2419230_0 PFAM Spermine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 335.0
GZD2_k127_2419230_1 Protein of unknown function (DUF2937) - - - 0.0000000000106 68.0
GZD2_k127_2451460_0 Carbohydrate-selective porin, OprB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 604.0
GZD2_k127_2451460_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 474.0
GZD2_k127_2451460_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 421.0
GZD2_k127_2451460_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 336.0
GZD2_k127_2451460_4 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
GZD2_k127_2451460_5 MlaC protein K07323 - - 0.00000000000005958 74.0
GZD2_k127_245942_0 MscS Mechanosensitive ion channel - - - 4.408e-220 693.0
GZD2_k127_245942_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.432e-199 628.0
GZD2_k127_245942_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 543.0
GZD2_k127_245942_3 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 385.0
GZD2_k127_245942_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 363.0
GZD2_k127_245942_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000001145 252.0
GZD2_k127_245942_6 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000006132 229.0
GZD2_k127_245942_7 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000001358 201.0
GZD2_k127_245942_8 Helix-turn-helix domain K15539 - - 0.00000000000000000000003403 105.0
GZD2_k127_2461768_0 COG0474 Cation transport ATPase K01535,K12955 - 3.6.3.6 0.0 1155.0
GZD2_k127_2461768_1 PFAM cytochrome c oxidase subunit I K00404 - 1.9.3.1 8.093e-291 895.0
GZD2_k127_2461768_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 284.0
GZD2_k127_2461768_12 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001196 252.0
GZD2_k127_2461768_13 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000003464 239.0
GZD2_k127_2461768_14 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000003694 230.0
GZD2_k127_2461768_15 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000001686 224.0
GZD2_k127_2461768_16 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000004794 188.0
GZD2_k127_2461768_17 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000005996 184.0
GZD2_k127_2461768_18 - - - - 0.0000000000000000000000000000000000000000000004518 170.0
GZD2_k127_2461768_19 - - - - 0.00000000000000000000000000000000000000941 149.0
GZD2_k127_2461768_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.727e-248 777.0
GZD2_k127_2461768_20 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000000008171 142.0
GZD2_k127_2461768_22 - - - - 0.000000000000000000009805 97.0
GZD2_k127_2461768_23 - - - - 0.00000000000000000001176 94.0
GZD2_k127_2461768_24 - - - - 0.000000000000001056 81.0
GZD2_k127_2461768_25 Protein of unknown function (DUF1614) - - - 0.00000001249 59.0
GZD2_k127_2461768_26 - - - - 0.0000000987 60.0
GZD2_k127_2461768_27 - - - - 0.0003006 46.0
GZD2_k127_2461768_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 7.93e-204 651.0
GZD2_k127_2461768_4 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 567.0
GZD2_k127_2461768_5 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 555.0
GZD2_k127_2461768_6 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 472.0
GZD2_k127_2461768_7 Sulfatase-modifying factor enzyme 1 K20333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 452.0
GZD2_k127_2461768_8 Cytochrome C oxidase, mono-heme subunit/FixO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 448.0
GZD2_k127_2461768_9 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 454.0
GZD2_k127_2463787_0 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000005863 206.0
GZD2_k127_2463787_1 Peptidase M50 - - - 0.000000000000000000000000000000383 132.0
GZD2_k127_2463787_2 - - - - 0.000000000000000000000001301 109.0
GZD2_k127_2463787_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000002001 63.0
GZD2_k127_2463787_4 UPF0126 domain - - - 0.0001499 45.0
GZD2_k127_2478604_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.931e-266 824.0
GZD2_k127_2478604_1 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 1.396e-228 711.0
GZD2_k127_2478604_2 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000006176 152.0
GZD2_k127_2479673_0 Enoyl-CoA hydratase/isomerase K07516 - 1.1.1.35 0.0 1157.0
GZD2_k127_2479673_1 AMP-binding enzyme K01897 - 6.2.1.3 7.617e-245 773.0
GZD2_k127_2479673_2 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 426.0
GZD2_k127_2479673_3 Acyl-CoA dehydrogenase, N-terminal domain K06445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 427.0
GZD2_k127_2479673_4 PFAM thioesterase superfamily protein K10806 - - 0.0000000000000000000000000000000000000000000000000000000000000006532 221.0
GZD2_k127_2481082_0 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 402.0
GZD2_k127_2481082_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 368.0
GZD2_k127_2481082_2 aminoacyl-histidine dipeptidase K01270 - - 0.0000000000000000000000000000000239 126.0
GZD2_k127_2481082_3 - - - - 0.000000000000000000000000005133 116.0
GZD2_k127_2481082_4 Protein of unknown function (DUF504) - - - 0.0000000000000000000001725 98.0
GZD2_k127_2481082_5 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000003238 83.0
GZD2_k127_2481082_6 biosynthesis protein K03328 - - 0.0000000004067 69.0
GZD2_k127_2488036_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 313.0
GZD2_k127_2488036_1 MarR family - - - 0.000000000000000000000000000000000000000000000000000000000000002671 220.0
GZD2_k127_2488036_2 diguanylate cyclase - - - 0.000000000000000003081 96.0
GZD2_k127_2488036_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000002112 72.0
GZD2_k127_2490268_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.735e-277 859.0
GZD2_k127_2490268_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 567.0
GZD2_k127_2490268_2 Glucodextranase, domain N K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000001073 213.0
GZD2_k127_2498929_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 449.0
GZD2_k127_2498929_1 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.000000000000000000000000000000000000002431 148.0
GZD2_k127_2498929_2 Flagellar regulator YcgR - - - 0.00000000001714 74.0
GZD2_k127_2498929_3 - - - - 0.000001029 57.0
GZD2_k127_2509324_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1599.0
GZD2_k127_2509324_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 2.868e-308 947.0
GZD2_k127_2512021_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 342.0
GZD2_k127_2512021_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 310.0
GZD2_k127_2512021_2 transcriptional K03719 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001511 256.0
GZD2_k127_2512021_5 - - - - 0.00000000000000000000000004276 110.0
GZD2_k127_2520089_0 PFAM iron permease FTR1 K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 352.0
GZD2_k127_2520089_1 PFAM ferric-uptake regulator K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000007419 237.0
GZD2_k127_2520089_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000001007 235.0
GZD2_k127_2520089_3 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
GZD2_k127_2520089_4 PFAM DEAD DEAH box helicase domain protein - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001795 192.0
GZD2_k127_2520089_5 Cupredoxin-like domain - - - 0.000000000000000000000000000006175 123.0
GZD2_k127_2520089_6 - - - - 0.000552 53.0
GZD2_k127_2529975_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.661e-222 693.0
GZD2_k127_2529975_1 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 1.196e-196 616.0
GZD2_k127_2529975_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 373.0
GZD2_k127_2529975_3 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001242 213.0
GZD2_k127_2537742_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 259.0
GZD2_k127_2537742_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000005643 166.0
GZD2_k127_2537742_2 PFAM peptidase M48 Ste24p - - - 0.00000000000000000007672 94.0
GZD2_k127_2554952_0 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 1.047e-318 988.0
GZD2_k127_2554952_1 PFAM aminotransferase class I and II K00812 - 2.6.1.1 4.023e-214 669.0
GZD2_k127_2554952_10 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.000000000000001103 79.0
GZD2_k127_2554952_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 394.0
GZD2_k127_2554952_3 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 397.0
GZD2_k127_2554952_4 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 417.0
GZD2_k127_2554952_5 TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000004562 227.0
GZD2_k127_2554952_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000003858 198.0
GZD2_k127_2554952_7 Cytochrome C biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000001792 190.0
GZD2_k127_2554952_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000006957 170.0
GZD2_k127_2554952_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000001502 119.0
GZD2_k127_255539_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 7.264e-219 685.0
GZD2_k127_255539_1 PFAM major facilitator superfamily MFS_1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 588.0
GZD2_k127_255539_2 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 314.0
GZD2_k127_255539_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000002506 145.0
GZD2_k127_2558135_0 Diguanylate cyclase - - - 4.858e-222 710.0
GZD2_k127_2558135_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 457.0
GZD2_k127_2558135_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 372.0
GZD2_k127_2558135_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 282.0
GZD2_k127_2558135_4 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003443 263.0
GZD2_k127_2558135_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004431 252.0
GZD2_k127_2558135_6 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003964 243.0
GZD2_k127_2558135_7 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000000000000000005832 196.0
GZD2_k127_2558135_8 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000003081 184.0
GZD2_k127_2558135_9 Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000000000000000001038 164.0
GZD2_k127_2562131_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1367.0
GZD2_k127_2562131_1 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 424.0
GZD2_k127_2562131_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000005602 231.0
GZD2_k127_2562131_3 - - - - 0.0000000000000007926 84.0
GZD2_k127_2565682_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 541.0
GZD2_k127_2565682_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 408.0
GZD2_k127_2565879_0 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 584.0
GZD2_k127_2565879_1 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000005765 244.0
GZD2_k127_2565879_2 - - - - 0.000000000000006655 76.0
GZD2_k127_2567371_0 Aminotransferase class-III K01845 - 5.4.3.8 3.88e-234 729.0
GZD2_k127_2567371_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 326.0
GZD2_k127_2567371_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000001285 213.0
GZD2_k127_2567371_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000005959 131.0
GZD2_k127_2569281_0 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002255 275.0
GZD2_k127_2569281_1 Sensors of blue-light using FAD - - - 0.000000000000000000000000000000000004856 144.0
GZD2_k127_2569281_2 CBS domain containing protein - - - 0.00000000003097 67.0
GZD2_k127_2570314_0 cytochrome c peroxidase K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 469.0
GZD2_k127_2570314_1 Transcriptional regulator, LysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 377.0
GZD2_k127_2570314_10 Cytochrome B561 K12262 - - 0.0000000000000000000000000301 108.0
GZD2_k127_2570314_11 Domain of Unknown Function (DUF1540) - - - 0.0000000000000000000000004814 118.0
GZD2_k127_2570314_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00005332 52.0
GZD2_k127_2570314_2 Transcriptional regulator K18900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 352.0
GZD2_k127_2570314_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 335.0
GZD2_k127_2570314_4 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 301.0
GZD2_k127_2570314_5 NAD(P)H-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 293.0
GZD2_k127_2570314_6 Shikimate / quinate 5-dehydrogenase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000002038 257.0
GZD2_k127_2570314_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005224 244.0
GZD2_k127_2570314_8 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000004356 220.0
GZD2_k127_2570314_9 - - - - 0.00000000000000000000000000000000000000000000006702 179.0
GZD2_k127_2592432_0 Uncharacterised protein family (UPF0160) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 444.0
GZD2_k127_2592432_1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001809 259.0
GZD2_k127_2592432_2 HIT domain - - - 0.0000000000000000000000000000000000000000000000000000000241 205.0
GZD2_k127_2592432_3 Domain of unknown function (DUF5062) - - - 0.00000000000000000000000000000000000000000004092 164.0
GZD2_k127_2592432_4 Yip1 domain - - - 0.00000000000000000000000000000000002521 143.0
GZD2_k127_2597984_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1119.0
GZD2_k127_2597984_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 598.0
GZD2_k127_2597984_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 308.0
GZD2_k127_2597984_11 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 297.0
GZD2_k127_2597984_12 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 287.0
GZD2_k127_2597984_13 N-terminal domain of galactosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000005359 216.0
GZD2_k127_2597984_14 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000008925 124.0
GZD2_k127_2597984_15 ThiS family K03154 - - 0.00000000000000005156 96.0
GZD2_k127_2597984_17 Glycosyl transferase family 2 - - - 0.000001431 61.0
GZD2_k127_2597984_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 460.0
GZD2_k127_2597984_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 404.0
GZD2_k127_2597984_4 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 378.0
GZD2_k127_2597984_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 377.0
GZD2_k127_2597984_6 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 362.0
GZD2_k127_2597984_7 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 343.0
GZD2_k127_2597984_8 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 330.0
GZD2_k127_2597984_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 324.0
GZD2_k127_2610227_0 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 430.0
GZD2_k127_2610227_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 308.0
GZD2_k127_2610227_2 PFAM Ankyrin K10799 - 2.4.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003927 274.0
GZD2_k127_2610227_3 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.000000000000000000000000000000000000000000000000000000000000005758 220.0
GZD2_k127_2610227_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000002645 218.0
GZD2_k127_2610227_5 response regulator receiver K13041 - - 0.0000000000000000000000000000000008649 142.0
GZD2_k127_2610227_6 SMART GGDEF domain containing protein - - - 0.000000000000000000000000000000005245 149.0
GZD2_k127_2610227_7 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.00000000004517 72.0
GZD2_k127_2622488_0 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 370.0
GZD2_k127_2622488_1 - - - - 0.0000000000000000000000000000000000000000000000003028 185.0
GZD2_k127_2622888_0 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 460.0
GZD2_k127_2622888_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 292.0
GZD2_k127_2622888_2 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 291.0
GZD2_k127_2622888_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000443 259.0
GZD2_k127_2632746_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 488.0
GZD2_k127_2632746_1 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 420.0
GZD2_k127_2632746_2 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 328.0
GZD2_k127_2632746_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000001683 179.0
GZD2_k127_2633244_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2629.0
GZD2_k127_2633244_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 9.3e-286 880.0
GZD2_k127_2633244_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 6.745e-215 669.0
GZD2_k127_2633244_3 PFAM cytochrome c class I K08738 - - 0.000000000000000000000000000000001494 132.0
GZD2_k127_2633244_4 PFAM cytochrome c class I K08738 - - 0.000000000000202 70.0
GZD2_k127_2637373_0 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 519.0
GZD2_k127_2637373_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000002489 216.0
GZD2_k127_2648207_0 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002174 268.0
GZD2_k127_2648207_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000005513 134.0
GZD2_k127_2648207_2 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.0000008948 51.0
GZD2_k127_2667030_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 5.845e-239 745.0
GZD2_k127_2667030_1 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 557.0
GZD2_k127_2667030_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 383.0
GZD2_k127_2667030_3 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 308.0
GZD2_k127_2667030_4 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 320.0
GZD2_k127_2667030_5 dehydratase - - - 0.00000000000000000005602 94.0
GZD2_k127_2677952_0 FtsX-like permease family K02004 - - 1.696e-259 829.0
GZD2_k127_2677952_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.157e-252 795.0
GZD2_k127_2677952_10 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 326.0
GZD2_k127_2677952_11 Protein of unknown function (DUF459) K09795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 295.0
GZD2_k127_2677952_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000431 259.0
GZD2_k127_2677952_13 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009691 246.0
GZD2_k127_2677952_14 pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000483 169.0
GZD2_k127_2677952_15 Nucleoside H+ symporter K05820 - - 0.00000000000004256 73.0
GZD2_k127_2677952_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 9.444e-204 638.0
GZD2_k127_2677952_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 8.309e-195 612.0
GZD2_k127_2677952_4 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 489.0
GZD2_k127_2677952_5 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 480.0
GZD2_k127_2677952_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 383.0
GZD2_k127_2677952_7 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 390.0
GZD2_k127_2677952_8 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 349.0
GZD2_k127_2677952_9 pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 336.0
GZD2_k127_2692429_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000004227 188.0
GZD2_k127_2692429_1 recombinase XerD K04763 - - 0.00000000000000000000000000002276 123.0
GZD2_k127_2692465_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1022.0
GZD2_k127_2693145_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 1.807e-276 857.0
GZD2_k127_2730252_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1813.0
GZD2_k127_2730252_1 Fumarate reductase flavoprotein C-term K00394 - 1.8.99.2 0.0 1283.0
GZD2_k127_2730252_10 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 455.0
GZD2_k127_2730252_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 418.0
GZD2_k127_2730252_12 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 424.0
GZD2_k127_2730252_13 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 388.0
GZD2_k127_2730252_14 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 378.0
GZD2_k127_2730252_15 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 387.0
GZD2_k127_2730252_16 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 349.0
GZD2_k127_2730252_17 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 340.0
GZD2_k127_2730252_18 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 311.0
GZD2_k127_2730252_19 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 293.0
GZD2_k127_2730252_2 Cysteine-rich domain - - - 9.042e-296 911.0
GZD2_k127_2730252_20 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001012 281.0
GZD2_k127_2730252_21 helix_turn_helix, Lux Regulon K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001007 269.0
GZD2_k127_2730252_22 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008004 262.0
GZD2_k127_2730252_23 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006855 245.0
GZD2_k127_2730252_24 PFAM UspA domain protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001012 254.0
GZD2_k127_2730252_25 Histidine triad (Hit) protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006888 238.0
GZD2_k127_2730252_26 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000000000000000004093 229.0
GZD2_k127_2730252_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000003461 215.0
GZD2_k127_2730252_28 DsrE/DsrF-like family K07236 - - 0.00000000000000000000000000000000000000000000000000000000001859 207.0
GZD2_k127_2730252_29 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000005536 202.0
GZD2_k127_2730252_3 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 2.032e-253 785.0
GZD2_k127_2730252_30 - - - - 0.000000000000000000000000000000000000000000000000000000001317 206.0
GZD2_k127_2730252_31 Domain of unknown function (DUF4279) - - - 0.000000000000000000000000000000000000000000000000000000001964 206.0
GZD2_k127_2730252_32 Cas6 Crispr - - - 0.00000000000000000000000000000000000000000000000000002471 194.0
GZD2_k127_2730252_33 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000009433 186.0
GZD2_k127_2730252_34 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000001924 180.0
GZD2_k127_2730252_35 DsrH like protein K07237 - - 0.0000000000000000000000000000000000781 135.0
GZD2_k127_2730252_36 Sulfurtransferase TusA K04085 - - 0.00000000000000000000000000000002038 127.0
GZD2_k127_2730252_37 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000001459 133.0
GZD2_k127_2730252_38 Bacterial protein of unknown function (DUF934) - - - 0.000000000000000000000000000001104 127.0
GZD2_k127_2730252_39 - - - - 0.0000000000000000000000000000252 122.0
GZD2_k127_2730252_4 PUA-like domain K00958 - 2.7.7.4 1.863e-228 712.0
GZD2_k127_2730252_41 cytochrome - - - 0.0000000000000000000000000405 112.0
GZD2_k127_2730252_42 - - - - 0.0000000000000000001235 89.0
GZD2_k127_2730252_43 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000002889 75.0
GZD2_k127_2730252_5 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 2.556e-226 702.0
GZD2_k127_2730252_6 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 551.0
GZD2_k127_2730252_7 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 540.0
GZD2_k127_2730252_8 4Fe-4S binding domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 488.0
GZD2_k127_2730252_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 481.0
GZD2_k127_2734793_0 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 546.0
GZD2_k127_2734793_1 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 394.0
GZD2_k127_2734793_2 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 266.0
GZD2_k127_2734793_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000002613 151.0
GZD2_k127_2734793_4 - - - - 0.00000000000005954 71.0
GZD2_k127_2734793_5 - - - - 0.0000000009831 69.0
GZD2_k127_2739635_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 456.0
GZD2_k127_2739635_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 439.0
GZD2_k127_2739635_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 433.0
GZD2_k127_2739635_3 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000001114 181.0
GZD2_k127_2742971_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1352.0
GZD2_k127_2742971_1 TIGRFAM efflux transporter, RND family, MFP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 440.0
GZD2_k127_2766224_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006668 280.0
GZD2_k127_2766224_1 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000001162 211.0
GZD2_k127_2766224_2 RDD family - - - 0.00000000000000000000000000000000004407 140.0
GZD2_k127_2788104_0 Oxidoreductase - - - 9.57e-285 885.0
GZD2_k127_2788104_1 Thi4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006521 250.0
GZD2_k127_2804546_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 516.0
GZD2_k127_2804546_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 285.0
GZD2_k127_2807454_0 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 586.0
GZD2_k127_2807454_1 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000003693 168.0
GZD2_k127_2807454_2 GtrA-like protein - - - 0.0000000000000003361 83.0
GZD2_k127_2832366_0 Belongs to the GPI family K01810 - 5.3.1.9 1.211e-244 777.0
GZD2_k127_2832366_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.263e-240 747.0
GZD2_k127_2832366_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 349.0
GZD2_k127_2841530_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.719e-278 870.0
GZD2_k127_2841530_1 Metallo-beta-lactamase superfamily - - - 0.000000000000001727 83.0
GZD2_k127_2841530_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000009545 59.0
GZD2_k127_2844385_0 SMART von Willebrand factor type A - - - 0.0 1071.0
GZD2_k127_2844385_1 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 1.958e-301 925.0
GZD2_k127_2844385_2 ATPase associated with various cellular activities AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 497.0
GZD2_k127_2844385_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 460.0
GZD2_k127_2844385_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 449.0
GZD2_k127_2844385_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 419.0
GZD2_k127_2844385_6 LysR substrate binding domain K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 406.0
GZD2_k127_2844385_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 376.0
GZD2_k127_2844385_8 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000002353 109.0
GZD2_k127_2865190_0 Glycosyl hydrolases family 6 K19668 - 3.2.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 286.0
GZD2_k127_2865190_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000004959 193.0
GZD2_k127_2865190_2 - - - - 0.000000000000000000000000005025 124.0
GZD2_k127_2897693_0 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003941 248.0
GZD2_k127_2897693_1 FecR protein - - - 0.000000000000000000000000000004874 131.0
GZD2_k127_2900368_0 PFAM cytochrome c biogenesis protein transmembrane region - - - 5.502e-240 753.0
GZD2_k127_2900368_1 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000002411 263.0
GZD2_k127_2900368_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000006599 252.0
GZD2_k127_2900368_3 methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001014 233.0
GZD2_k127_2900368_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000003571 199.0
GZD2_k127_2900368_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000014 115.0
GZD2_k127_2947414_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 476.0
GZD2_k127_2947414_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 366.0
GZD2_k127_2947414_2 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 313.0
GZD2_k127_2947414_3 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000199 158.0
GZD2_k127_2969473_0 permease K07089 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 482.0
GZD2_k127_2969473_1 PFAM cytochrome c, class I K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 422.0
GZD2_k127_2969473_2 - - - - 0.000000000000000000000000000000000000000008516 158.0
GZD2_k127_2969473_3 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000001711 85.0
GZD2_k127_2973365_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 9.862e-224 701.0
GZD2_k127_2973365_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 493.0
GZD2_k127_2973365_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000006874 83.0
GZD2_k127_298338_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.279e-310 960.0
GZD2_k127_298338_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000002718 169.0
GZD2_k127_299169_0 major facilitator superfamily K03446 - - 5.03e-257 800.0
GZD2_k127_299169_1 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 437.0
GZD2_k127_299169_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 295.0
GZD2_k127_299169_3 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009122 267.0
GZD2_k127_299169_4 Transcription regulator that can specifically activate or repress expression of target genes K06075 - - 0.0000000000000000000000000000000000000008634 155.0
GZD2_k127_299169_5 response regulator receiver - - - 0.0000000000000000000000000000000000000009318 155.0
GZD2_k127_299169_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000174 113.0
GZD2_k127_299169_7 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000001381 97.0
GZD2_k127_301336_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 4.386e-238 744.0
GZD2_k127_301336_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00003331 46.0
GZD2_k127_3038006_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.717e-300 923.0
GZD2_k127_3038006_1 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 310.0
GZD2_k127_3038006_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 281.0
GZD2_k127_3038006_3 Regulatory protein, FmdB family - - - 0.0000000000000000000000000000003197 123.0
GZD2_k127_303804_0 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 302.0
GZD2_k127_303804_1 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.00000000000000000000000000286 116.0
GZD2_k127_303804_2 Secreted protein - - - 0.00005108 51.0
GZD2_k127_3067469_0 MacB-like periplasmic core domain K02004 - - 2.453e-204 642.0
GZD2_k127_3067469_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 351.0
GZD2_k127_3081056_0 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 0.0 1568.0
GZD2_k127_3081056_1 TIGRFAM efflux transporter, RND family, MFP subunit K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 387.0
GZD2_k127_313767_0 RNB K01147 - 3.1.13.1 3.15e-310 959.0
GZD2_k127_313767_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 553.0
GZD2_k127_313767_10 Ca2 -binding protein (EF-Hand superfamily - - - 0.0000000000000006165 85.0
GZD2_k127_313767_2 PFAM aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 467.0
GZD2_k127_313767_3 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 400.0
GZD2_k127_313767_4 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 331.0
GZD2_k127_313767_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 313.0
GZD2_k127_313767_6 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 287.0
GZD2_k127_313767_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000004163 251.0
GZD2_k127_313767_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000003903 199.0
GZD2_k127_313767_9 Protein of unknown function (DUF493) K09158 - - 0.00000000000000000000000000005819 129.0
GZD2_k127_3141864_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1142.0
GZD2_k127_3141864_1 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 317.0
GZD2_k127_3141864_2 Universal stress protein family - - - 0.0000000000000000000000000000000000000000002449 160.0
GZD2_k127_315980_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1139.0
GZD2_k127_315980_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 2.91e-227 710.0
GZD2_k127_315980_2 Cytochrome b(N-terminal)/b6/petB K00412 - - 2.901e-222 694.0
GZD2_k127_315980_3 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 4.113e-219 691.0
GZD2_k127_315980_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 586.0
GZD2_k127_315980_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 404.0
GZD2_k127_315980_6 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 399.0
GZD2_k127_315980_7 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001506 275.0
GZD2_k127_315980_8 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004189 262.0
GZD2_k127_315980_9 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000004735 162.0
GZD2_k127_3251413_0 Molybdopterin oxidoreductase Fe4S4 domain K00372 - - 0.0 1384.0
GZD2_k127_3251413_1 PFAM Major Facilitator Superfamily K02575 - - 1.506e-200 631.0
GZD2_k127_3251413_2 ANTAR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 461.0
GZD2_k127_3251413_3 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 374.0
GZD2_k127_3269887_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1102.0
GZD2_k127_3269887_1 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 561.0
GZD2_k127_3269887_2 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 398.0
GZD2_k127_3269887_3 - - - - 0.00000000000000000000003625 109.0
GZD2_k127_3269887_4 Sporulation related domain K03749 - - 0.000000000000006703 78.0
GZD2_k127_3270993_0 - - - - 0.000000000000000000000000009885 114.0
GZD2_k127_3270993_1 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000963 108.0
GZD2_k127_3306984_0 PFAM DEAD DEAH box helicase domain protein - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 421.0
GZD2_k127_3306984_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000000004093 206.0
GZD2_k127_3306984_2 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000114 142.0
GZD2_k127_3313258_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.935e-313 967.0
GZD2_k127_3313258_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 1.155e-304 940.0
GZD2_k127_3313258_10 DSBA-like thioredoxin domain K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000006264 233.0
GZD2_k127_3313258_11 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000000000000557 196.0
GZD2_k127_3313258_12 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000002318 193.0
GZD2_k127_3313258_13 protein conserved in bacteria K03690 - - 0.0000000000000000000000000000000000000000000000004646 182.0
GZD2_k127_3313258_14 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000000000002101 179.0
GZD2_k127_3313258_15 Sporulation related domain - - - 0.00000000000000000000000000002015 124.0
GZD2_k127_3313258_17 - - - - 0.00000000001185 64.0
GZD2_k127_3313258_18 oxidoreductase activity, acting on diphenols and related substances as donors K00424 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019867,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0071944 1.10.3.14 0.0000003997 62.0
GZD2_k127_3313258_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.048e-254 794.0
GZD2_k127_3313258_3 Polyphosphate kinase 2 (PPK2) - - - 5.006e-244 763.0
GZD2_k127_3313258_4 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.13e-198 630.0
GZD2_k127_3313258_5 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 550.0
GZD2_k127_3313258_6 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 527.0
GZD2_k127_3313258_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 412.0
GZD2_k127_3313258_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 344.0
GZD2_k127_3313258_9 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 284.0
GZD2_k127_3315667_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 1.638e-248 799.0
GZD2_k127_3315667_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 295.0
GZD2_k127_3315667_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000007383 216.0
GZD2_k127_3315667_3 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000006971 183.0
GZD2_k127_3315840_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 9.648e-196 616.0
GZD2_k127_3315840_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 606.0
GZD2_k127_3315840_2 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 514.0
GZD2_k127_3315840_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 400.0
GZD2_k127_3315840_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 305.0
GZD2_k127_3315840_5 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000002204 254.0
GZD2_k127_3315840_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000002486 69.0
GZD2_k127_3320997_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 5.464e-251 780.0
GZD2_k127_3320997_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 373.0
GZD2_k127_3320997_2 Membrane K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000007141 248.0
GZD2_k127_3334766_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1208.0
GZD2_k127_3334766_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 477.0
GZD2_k127_3335078_0 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 524.0
GZD2_k127_3335078_1 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 462.0
GZD2_k127_3335078_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 329.0
GZD2_k127_3335078_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 326.0
GZD2_k127_3335078_4 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002518 275.0
GZD2_k127_3335078_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000002482 168.0
GZD2_k127_3363865_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1411.0
GZD2_k127_3363865_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 274.0
GZD2_k127_3364556_0 ABC transporter C-terminal domain K15738 - - 0.0 1039.0
GZD2_k127_3364556_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 2.272e-242 762.0
GZD2_k127_3364556_10 Segregation and condensation complex subunit ScpB K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001539 272.0
GZD2_k127_3364556_11 Belongs to the ABC transporter superfamily K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002325 281.0
GZD2_k127_3364556_12 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001442 278.0
GZD2_k127_3364556_13 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003169 252.0
GZD2_k127_3364556_14 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000011 241.0
GZD2_k127_3364556_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000001597 207.0
GZD2_k127_3364556_16 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000001762 202.0
GZD2_k127_3364556_17 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000006569 193.0
GZD2_k127_3364556_18 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000000000000000005095 149.0
GZD2_k127_3364556_19 Ppx GppA phosphatase - - - 0.0000000000000000000000000000005923 130.0
GZD2_k127_3364556_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 566.0
GZD2_k127_3364556_20 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000009973 88.0
GZD2_k127_3364556_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 481.0
GZD2_k127_3364556_4 TRAP transporter solute receptor TAXI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 439.0
GZD2_k127_3364556_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 409.0
GZD2_k127_3364556_6 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 405.0
GZD2_k127_3364556_7 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 413.0
GZD2_k127_3364556_8 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 314.0
GZD2_k127_3364556_9 TIGRFAM Sua5 YciO YrdC YwlC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 302.0
GZD2_k127_3373046_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 546.0
GZD2_k127_3373046_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 366.0
GZD2_k127_3373046_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 351.0
GZD2_k127_3373046_3 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 340.0
GZD2_k127_3373046_4 Acyl carrier protein phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002547 252.0
GZD2_k127_337625_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 295.0
GZD2_k127_337625_1 InterPro IPR014922 - - - 0.000000000000000000000000000000000000000000000000003281 187.0
GZD2_k127_3388122_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1198.0
GZD2_k127_3388122_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 8.548e-289 891.0
GZD2_k127_3388122_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 1.865e-238 745.0
GZD2_k127_3388122_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 413.0
GZD2_k127_3388122_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 378.0
GZD2_k127_3388122_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 301.0
GZD2_k127_3403541_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 605.0
GZD2_k127_3403541_1 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000001127 209.0
GZD2_k127_3403541_2 FeS assembly SUF system protein - - - 0.0000000000000000000000000000000000000004073 151.0
GZD2_k127_3403541_3 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.000000000000000000000000000007774 119.0
GZD2_k127_3403541_4 assembly protein SufD K09015 - - 0.000000009564 56.0
GZD2_k127_3406053_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1502.0
GZD2_k127_3406053_1 Major facilitator superfamily - - - 2.013e-292 903.0
GZD2_k127_3406053_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 5.298e-220 686.0
GZD2_k127_3406053_3 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 246.0
GZD2_k127_3406053_4 ATPase (P-type) K01535 - 3.6.3.6 0.00000000000000000000000000000000000000000000000000009489 189.0
GZD2_k127_3409392_0 - - - - 3.293e-243 768.0
GZD2_k127_3409392_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.172e-239 745.0
GZD2_k127_3409392_2 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 400.0
GZD2_k127_3409392_3 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 288.0
GZD2_k127_3409392_4 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009717 223.0
GZD2_k127_3440981_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 572.0
GZD2_k127_3440994_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 571.0
GZD2_k127_3452945_0 Belongs to the UPF0061 (SELO) family - - - 6.409e-214 675.0
GZD2_k127_3452945_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 343.0
GZD2_k127_3452945_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000005406 147.0
GZD2_k127_3452945_3 - - - - 0.0000000000005538 75.0
GZD2_k127_346929_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.058e-286 886.0
GZD2_k127_346929_1 MMPL family - - - 5.475e-280 880.0
GZD2_k127_346929_10 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 300.0
GZD2_k127_346929_11 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000204 245.0
GZD2_k127_346929_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000009464 220.0
GZD2_k127_346929_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000001748 214.0
GZD2_k127_346929_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000254 203.0
GZD2_k127_346929_15 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000002945 191.0
GZD2_k127_346929_16 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000004675 194.0
GZD2_k127_346929_17 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000001024 142.0
GZD2_k127_346929_18 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286,K12976,K16079 - - 0.0000000000000000001676 101.0
GZD2_k127_346929_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.459e-196 618.0
GZD2_k127_346929_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 508.0
GZD2_k127_346929_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 463.0
GZD2_k127_346929_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 413.0
GZD2_k127_346929_6 Glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 384.0
GZD2_k127_346929_7 pteridine-dependent deoxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 343.0
GZD2_k127_346929_8 MltA-interacting protein MipA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 327.0
GZD2_k127_346929_9 Polysaccharide deacetylase K01452 - 3.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 307.0
GZD2_k127_3472514_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0 1482.0
GZD2_k127_3472514_1 Belongs to the UPF0753 family K09822 - - 0.0 1297.0
GZD2_k127_3472514_10 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 501.0
GZD2_k127_3472514_11 LysR substrate binding domain K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 499.0
GZD2_k127_3472514_12 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 502.0
GZD2_k127_3472514_13 LysR substrate binding domain K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 488.0
GZD2_k127_3472514_14 phosphorelay sensor kinase activity K02342,K02851 - 2.7.7.7,2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 488.0
GZD2_k127_3472514_15 Short-chain dehydrogenase reductase (SDR) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 368.0
GZD2_k127_3472514_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 350.0
GZD2_k127_3472514_17 AAA domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 301.0
GZD2_k127_3472514_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 291.0
GZD2_k127_3472514_19 PFAM HPP family protein K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 287.0
GZD2_k127_3472514_2 von Willebrand factor, type A - - - 0.0 1229.0
GZD2_k127_3472514_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000852 254.0
GZD2_k127_3472514_21 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000001219 237.0
GZD2_k127_3472514_22 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000007494 228.0
GZD2_k127_3472514_23 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000007863 221.0
GZD2_k127_3472514_24 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000001828 200.0
GZD2_k127_3472514_25 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000000000000188 205.0
GZD2_k127_3472514_26 - - - - 0.000000000000000000000000000000000000000000000000000000002836 202.0
GZD2_k127_3472514_27 Nitrogen regulatory protein P-II - - - 0.000000000000000000000000000000000000000000000000000003701 193.0
GZD2_k127_3472514_28 BMC - - - 0.000000000000000000000000000000000000000000000000001206 183.0
GZD2_k127_3472514_29 BMC - - - 0.00000000000000000000000000000000000000000000000006189 179.0
GZD2_k127_3472514_3 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.53e-309 949.0
GZD2_k127_3472514_30 BMC - - - 0.000000000000000000000000000000000000000000000002091 175.0
GZD2_k127_3472514_31 - - - - 0.0000000000000000000000000000000000000000000003092 168.0
GZD2_k127_3472514_32 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000000000000000000000000136 165.0
GZD2_k127_3472514_33 - - - - 0.00000000000000000000000000000000000000000001558 166.0
GZD2_k127_3472514_34 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000000000000000000000001983 153.0
GZD2_k127_3472514_35 Ankyrin repeat domain-containing protein 50-like K21440 - - 0.000000000000000000000000000000000002759 153.0
GZD2_k127_3472514_36 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000002747 128.0
GZD2_k127_3472514_37 - - - - 0.00000000000000000000000002138 115.0
GZD2_k127_3472514_39 ankyrin 3, node of Ranvier (ankyrin G) K10277,K10380 GO:0000226,GO:0000278,GO:0000281,GO:0000323,GO:0000902,GO:0000904,GO:0000910,GO:0001508,GO:0002027,GO:0002028,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003205,GO:0003230,GO:0003254,GO:0003279,GO:0003283,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005783,GO:0005794,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0005911,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006888,GO:0006892,GO:0006893,GO:0006928,GO:0006935,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0006996,GO:0007009,GO:0007010,GO:0007016,GO:0007017,GO:0007049,GO:0007154,GO:0007165,GO:0007267,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007507,GO:0007528,GO:0007600,GO:0007605,GO:0007610,GO:0007611,GO:0007613,GO:0007614,GO:0008015,GO:0008016,GO:0008092,GO:0008104,GO:0008150,GO:0008582,GO:0009605,GO:0009653,GO:0009893,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010171,GO:0010256,GO:0010468,GO:0010522,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010648,GO:0010649,GO:0010650,GO:0010765,GO:0010880,GO:0010881,GO:0010882,GO:0010959,GO:0010960,GO:0012505,GO:0014069,GO:0014704,GO:0014731,GO:0015031,GO:0015459,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016049,GO:0016192,GO:0016247,GO:0016323,GO:0016328,GO:0016528,GO:0016529,GO:0019222,GO:0019226,GO:0019228,GO:0019722,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0022008,GO:0022402,GO:0022407,GO:0022409,GO:0022607,GO:0022898,GO:0023051,GO:0023052,GO:0023057,GO:0030001,GO:0030003,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030048,GO:0030054,GO:0030154,GO:0030155,GO:0030182,GO:0030315,GO:0030424,GO:0030425,GO:0030507,GO:0030674,GO:0031175,GO:0031224,GO:0031226,GO:0031430,GO:0031594,GO:0031647,GO:0031672,GO:0031674,GO:0032026,GO:0032279,GO:0032386,GO:0032388,GO:0032409,GO:0032410,GO:0032411,GO:0032412,GO:0032413,GO:0032414,GO:0032501,GO:0032502,GO:0032507,GO:0032879,GO:0032880,GO:0032970,GO:0032989,GO:0032990,GO:0033036,GO:0033157,GO:0033267,GO:0033268,GO:0033270,GO:0033292,GO:0033365,GO:0033563,GO:0034110,GO:0034112,GO:0034394,GO:0034613,GO:0034762,GO:0034763,GO:0034764,GO:0034765,GO:0034766,GO:0034767,GO:0035556,GO:0035637,GO:0036062,GO:0036309,GO:0036371,GO:0036477,GO:0040007,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042592,GO:0042692,GO:0042734,GO:0042886,GO:0042995,GO:0043001,GO:0043005,GO:0043034,GO:0043194,GO:0043195,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043266,GO:0043267,GO:0043268,GO:0043269,GO:0043270,GO:0043271,GO:0043292,GO:0043679,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044091,GO:0044092,GO:0044093,GO:0044291,GO:0044304,GO:0044306,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045170,GO:0045184,GO:0045185,GO:0045202,GO:0045211,GO:0045296,GO:0045760,GO:0045785,GO:0045838,GO:0045887,GO:0045927,GO:0046907,GO:0048193,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048588,GO:0048589,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048675,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050803,GO:0050804,GO:0050805,GO:0050807,GO:0050808,GO:0050821,GO:0050839,GO:0050877,GO:0050890,GO:0050896,GO:0050954,GO:0051049,GO:0051050,GO:0051051,GO:0051094,GO:0051117,GO:0051128,GO:0051130,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051270,GO:0051279,GO:0051282,GO:0051301,GO:0051641,GO:0051649,GO:0051651,GO:0051716,GO:0051899,GO:0051924,GO:0051928,GO:0051960,GO:0051962,GO:0051963,GO:0051965,GO:0055001,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055117,GO:0060047,GO:0060048,GO:0060090,GO:0060249,GO:0060255,GO:0060306,GO:0060307,GO:0060341,GO:0060560,GO:0061024,GO:0061061,GO:0061337,GO:0061564,GO:0061640,GO:0061951,GO:0065007,GO:0065008,GO:0065009,GO:0070050,GO:0070201,GO:0070252,GO:0070296,GO:0070727,GO:0070838,GO:0070887,GO:0070972,GO:0071241,GO:0071248,GO:0071286,GO:0071702,GO:0071705,GO:0071709,GO:0071840,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0072657,GO:0072658,GO:0072659,GO:0072660,GO:0086001,GO:0086002,GO:0086003,GO:0086004,GO:0086005,GO:0086010,GO:0086012,GO:0086014,GO:0086015,GO:0086018,GO:0086019,GO:0086026,GO:0086036,GO:0086046,GO:0086065,GO:0086066,GO:0086070,GO:0086091,GO:0090087,GO:0090150,GO:0090257,GO:0090313,GO:0090314,GO:0090316,GO:0097060,GO:0097447,GO:0097458,GO:0097485,GO:0098590,GO:0098771,GO:0098772,GO:0098793,GO:0098794,GO:0098876,GO:0098900,GO:0098901,GO:0098902,GO:0098904,GO:0098907,GO:0098910,GO:0098984,GO:0099080,GO:0099081,GO:0099106,GO:0099177,GO:0099512,GO:0099572,GO:0099612,GO:0099623,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1900073,GO:1900074,GO:1900825,GO:1900827,GO:1901016,GO:1901017,GO:1901018,GO:1901019,GO:1901021,GO:1901379,GO:1901380,GO:1901381,GO:1902259,GO:1902260,GO:1902305,GO:1902307,GO:1903047,GO:1903115,GO:1903169,GO:1903522,GO:1903533,GO:1903779,GO:1903817,GO:1903827,GO:1903829,GO:1904062,GO:1904063,GO:1904064,GO:1904181,GO:1904396,GO:1904398,GO:1904427,GO:1904951,GO:1905475,GO:1905477,GO:1990138,GO:1990778,GO:2000026,GO:2000649,GO:2000651,GO:2001257,GO:2001258,GO:2001259 1.14.11.27 0.000000000000000000001591 106.0
GZD2_k127_3472514_4 Carboxysome Shell Carbonic Anhydrase - - - 2.367e-276 856.0
GZD2_k127_3472514_40 - - - - 0.000000000000000000003367 99.0
GZD2_k127_3472514_41 Chemoreceptor zinc-binding domain - - - 0.000000000000000002627 92.0
GZD2_k127_3472514_42 dehydratase K01724 - 4.2.1.96 0.0000000000007879 72.0
GZD2_k127_3472514_5 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 5.03e-271 842.0
GZD2_k127_3472514_6 Carboxysome shell peptide mid-region - - - 2.315e-252 792.0
GZD2_k127_3472514_7 NADH Ubiquinone plastoquinone (Complex I) K05577 - 1.6.5.3 3.096e-227 716.0
GZD2_k127_3472514_8 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 603.0
GZD2_k127_3472514_9 LysR substrate binding domain K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 556.0
GZD2_k127_3484891_0 Putative diguanylate phosphodiesterase - - - 1.203e-220 709.0
GZD2_k127_3484891_1 TIGRFAM PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 489.0
GZD2_k127_3484891_2 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 295.0
GZD2_k127_3484891_3 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000001134 194.0
GZD2_k127_3490391_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 1.975e-296 931.0
GZD2_k127_3490391_1 Part of a membrane complex involved in electron transport K03615 - - 9.69e-196 625.0
GZD2_k127_3490391_10 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000552 187.0
GZD2_k127_3490391_11 - - - - 0.00000000000000000000000000000001069 138.0
GZD2_k127_3490391_12 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000007229 128.0
GZD2_k127_3490391_13 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000002587 123.0
GZD2_k127_3490391_14 SMART RNA-binding S4 domain protein K04762 - - 0.000000000000000000000000000007955 121.0
GZD2_k127_3490391_15 Short C-terminal domain K08982 - - 0.0000000000000003571 81.0
GZD2_k127_3490391_16 YfaZ precursor - - - 0.000000003655 66.0
GZD2_k127_3490391_2 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 528.0
GZD2_k127_3490391_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 353.0
GZD2_k127_3490391_4 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 343.0
GZD2_k127_3490391_5 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 319.0
GZD2_k127_3490391_6 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 285.0
GZD2_k127_3490391_7 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001518 285.0
GZD2_k127_3490391_8 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003272 268.0
GZD2_k127_3490391_9 - - - - 0.000000000000000000000000000000000000000000000000000004591 194.0
GZD2_k127_3493216_0 Universal stress protein - - - 0.0000000007545 60.0
GZD2_k127_3521337_0 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 537.0
GZD2_k127_3521337_1 Hydrogenase maturation protease - - - 0.000000000000000000000000000000000000000000000000004973 185.0
GZD2_k127_3521337_2 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000001144 111.0
GZD2_k127_3521337_3 HupH hydrogenase expression protein, C-terminal conserved region - - - 0.00000000000000000000000004191 115.0
GZD2_k127_3526279_0 PFAM ABC transporter related - - - 2.193e-240 749.0
GZD2_k127_3526279_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 1.927e-232 723.0
GZD2_k127_3526279_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 511.0
GZD2_k127_352866_0 Methyltransferase domain K19620 - - 1.774e-203 643.0
GZD2_k127_352866_1 Histidine kinase K19621 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 570.0
GZD2_k127_352866_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 483.0
GZD2_k127_352866_3 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 482.0
GZD2_k127_352866_4 response regulator K19622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 406.0
GZD2_k127_352866_5 response regulator K19623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 372.0
GZD2_k127_352866_6 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 296.0
GZD2_k127_352866_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000001058 178.0
GZD2_k127_3536570_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1031.0
GZD2_k127_3536570_1 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 1.504e-219 686.0
GZD2_k127_3536570_2 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 460.0
GZD2_k127_3536570_3 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 459.0
GZD2_k127_3536570_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 402.0
GZD2_k127_3536570_5 EamA-like transporter family K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 350.0
GZD2_k127_3536570_6 MltA-interacting MipA family protein K07274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 337.0
GZD2_k127_3536570_7 SpoIIAA-like - - - 0.0000000000000000000000000000000000000000000000001069 179.0
GZD2_k127_3536570_8 - - - - 0.000000000000000000000000001834 116.0
GZD2_k127_3536570_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000005181 98.0
GZD2_k127_3572713_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 2.125e-203 638.0
GZD2_k127_3572713_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 595.0
GZD2_k127_3572713_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000002081 183.0
GZD2_k127_3574649_0 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000000002459 216.0
GZD2_k127_3574649_1 - - - - 0.000000000000000000000000000000000000009888 152.0
GZD2_k127_3574649_2 - - - - 0.000000000000000000002895 96.0
GZD2_k127_3574649_3 Bacterial protein of unknown function (DUF924) - - - 0.0000032 51.0
GZD2_k127_3577391_0 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 441.0
GZD2_k127_3577391_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 399.0
GZD2_k127_3577391_2 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000002122 167.0
GZD2_k127_3584339_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.061e-241 759.0
GZD2_k127_3584339_1 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 424.0
GZD2_k127_3596547_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 507.0
GZD2_k127_3596547_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 294.0
GZD2_k127_3596547_2 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000000001434 178.0
GZD2_k127_3598330_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 332.0
GZD2_k127_3598330_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 326.0
GZD2_k127_3598330_2 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 291.0
GZD2_k127_3598330_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002561 273.0
GZD2_k127_3598330_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000000003476 158.0
GZD2_k127_3607398_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1311.0
GZD2_k127_3607398_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.212e-216 680.0
GZD2_k127_3607398_2 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 486.0
GZD2_k127_3607398_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 381.0
GZD2_k127_3607398_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006413 268.0
GZD2_k127_3607398_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000006211 150.0
GZD2_k127_3607398_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000003744 61.0
GZD2_k127_365474_0 Molydopterin dinucleotide binding domain - - - 0.0 1499.0
GZD2_k127_365474_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1121.0
GZD2_k127_365474_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 3.28e-318 988.0
GZD2_k127_365474_3 Formate dehydrogenase N, transmembrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 511.0
GZD2_k127_365474_4 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 390.0
GZD2_k127_365474_5 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 329.0
GZD2_k127_365474_6 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 307.0
GZD2_k127_365474_7 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000001256 238.0
GZD2_k127_365474_8 Molybdopterin-guanine dinucleotide biosynthesis protein MobA K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000004057 177.0
GZD2_k127_365474_9 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000001225 94.0
GZD2_k127_3678524_0 PFAM ABC transporter related K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 421.0
GZD2_k127_3678524_1 VanZ like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 354.0
GZD2_k127_3678524_2 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 286.0
GZD2_k127_3678524_3 Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000000000000000000000000000000000000000000000486 217.0
GZD2_k127_3678524_4 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000005036 188.0
GZD2_k127_3678524_5 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000201 113.0
GZD2_k127_3680967_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.509e-260 806.0
GZD2_k127_3680967_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 606.0
GZD2_k127_3680967_2 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000001485 245.0
GZD2_k127_3683990_0 permeases of the drug metabolite transporter (Dmt) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 431.0
GZD2_k127_3683990_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 427.0
GZD2_k127_3683990_2 PFAM GumN family protein K09973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008547 287.0
GZD2_k127_3683990_3 - - - - 0.000000000000000000000000000000000000000000000000009 184.0
GZD2_k127_3683990_4 Protein of unknown function (DUF3034) - - - 0.0000000000000000000000000000000000001624 152.0
GZD2_k127_3683990_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000002348 108.0
GZD2_k127_3683990_6 - - - - 0.000000000000009057 82.0
GZD2_k127_3691110_0 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000001558 238.0
GZD2_k127_3691110_1 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000001206 209.0
GZD2_k127_3691110_2 Protein of unknown function (DUF3565) - - - 0.00000000000000000000000000008245 126.0
GZD2_k127_3726222_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 7.468e-246 766.0
GZD2_k127_3726222_1 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 546.0
GZD2_k127_3726222_2 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 503.0
GZD2_k127_3726222_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 483.0
GZD2_k127_3726222_4 chorismate binding enzyme K01665,K02619,K03342,K13503,K13950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003449 274.0
GZD2_k127_3726222_5 - - - - 0.0000003463 54.0
GZD2_k127_3735093_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.746e-211 664.0
GZD2_k127_3735093_1 Periplasmic sensor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 591.0
GZD2_k127_3735093_2 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 527.0
GZD2_k127_3735093_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004354 246.0
GZD2_k127_3735093_4 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000004004 244.0
GZD2_k127_3735093_5 Domain of unknown function (DUF4154) - - - 0.00000000000000000000002693 108.0
GZD2_k127_374512_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 441.0
GZD2_k127_374512_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 349.0
GZD2_k127_374512_2 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004677 269.0
GZD2_k127_374512_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000000000004885 113.0
GZD2_k127_3774079_0 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 9.912e-250 782.0
GZD2_k127_3774079_1 NADH flavin oxidoreductase NADH oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 581.0
GZD2_k127_3774079_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 544.0
GZD2_k127_3774079_3 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 407.0
GZD2_k127_3774079_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
GZD2_k127_3774079_5 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001029 267.0
GZD2_k127_3774079_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009589 252.0
GZD2_k127_3774079_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000116 248.0
GZD2_k127_3774079_8 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000000000000000000000000005986 224.0
GZD2_k127_3774079_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000009612 170.0
GZD2_k127_3775342_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 4.242e-207 645.0
GZD2_k127_3775342_1 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 8.198e-203 636.0
GZD2_k127_3775342_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 587.0
GZD2_k127_3775342_3 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000004115 121.0
GZD2_k127_3776405_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1652.0
GZD2_k127_3776405_1 PFAM thiamine pyrophosphate K01652 - 2.2.1.6 0.0 1012.0
GZD2_k127_3776405_11 Protein of unknown function (DUF1622) - - - 0.0000000325 59.0
GZD2_k127_3776405_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 2.487e-235 736.0
GZD2_k127_3776405_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 7.309e-204 636.0
GZD2_k127_3776405_4 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 486.0
GZD2_k127_3776405_5 PFAM permease YjgP YjgQ family protein K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 494.0
GZD2_k127_3776405_6 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008856 276.0
GZD2_k127_3776405_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003544 264.0
GZD2_k127_3776405_8 PFAM DNA polymerase III chi subunit HolC K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000007682 199.0
GZD2_k127_3776405_9 Protein of unknown function (DUF3106) - - - 0.00000000000006993 79.0
GZD2_k127_3777339_0 Sulfate permease family K03321 - - 6.543e-207 653.0
GZD2_k127_3777339_1 daunorubicin resistance ABC transporter K01990,K18232 - - 0.000000000000000000001114 96.0
GZD2_k127_3814184_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 422.0
GZD2_k127_3814184_1 Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000006113 168.0
GZD2_k127_3814184_2 ACT domain - - - 0.000000000000000000000000008395 112.0
GZD2_k127_3819628_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 583.0
GZD2_k127_3819628_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005573 287.0
GZD2_k127_3819628_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007886 270.0
GZD2_k127_3819628_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001564 242.0
GZD2_k127_3819628_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000002158 230.0
GZD2_k127_3819628_5 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000009237 222.0
GZD2_k127_3819628_6 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000001682 214.0
GZD2_k127_3819628_7 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000009876 186.0
GZD2_k127_3819628_8 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000001551 92.0
GZD2_k127_3823067_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1596.0
GZD2_k127_3823067_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1546.0
GZD2_k127_3823067_2 metal-dependent phosphohydrolase HD sub domain - - - 1.538e-214 679.0
GZD2_k127_3823067_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 478.0
GZD2_k127_3823067_4 Rhodanese Homology Domain K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 398.0
GZD2_k127_3823067_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002029 272.0
GZD2_k127_3823067_6 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000002129 240.0
GZD2_k127_3823067_7 PFAM FecR protein - - - 0.0000000000000000000000000000865 129.0
GZD2_k127_3823067_8 Protein of unknown function (DUF560) - - - 0.0000000000000004137 91.0
GZD2_k127_385935_0 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 421.0
GZD2_k127_385935_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 304.0
GZD2_k127_385935_2 PFAM GumN family protein K09973 - - 0.00000000000000005955 82.0
GZD2_k127_3879339_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.001e-258 797.0
GZD2_k127_3879339_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 1.105e-200 631.0
GZD2_k127_3879339_10 Barstar (barnase inhibitor) - - - 0.0000000000000000000000000000000000002458 149.0
GZD2_k127_3879339_11 - - - - 0.00000000000000000000001322 116.0
GZD2_k127_3879339_12 Collagen alpha-6(IV) chain K06237 GO:0005575,GO:0005576,GO:0005581,GO:0005587,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0008150,GO:0009987,GO:0012505,GO:0016043,GO:0030198,GO:0031012,GO:0031974,GO:0032991,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0062023,GO:0070013,GO:0071840,GO:0098642,GO:0098644,GO:0098645,GO:0098651,GO:0099080,GO:0099081 - 0.00002779 53.0
GZD2_k127_3879339_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 599.0
GZD2_k127_3879339_3 PFAM metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 373.0
GZD2_k127_3879339_4 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 340.0
GZD2_k127_3879339_5 Arginase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 323.0
GZD2_k127_3879339_6 Phenazine biosynthesis protein PhzF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 315.0
GZD2_k127_3879339_7 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 308.0
GZD2_k127_3879339_8 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000000000000000001525 244.0
GZD2_k127_3879339_9 PFAM guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.00000000000000000000000000000000000000000000006155 171.0
GZD2_k127_3955612_0 Multi-copper - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 531.0
GZD2_k127_3955612_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 485.0
GZD2_k127_3955612_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 332.0
GZD2_k127_3955612_3 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 304.0
GZD2_k127_3955612_4 Regulatory protein MarR - - - 0.00000000000000000000000000000000000000000000000000000000297 202.0
GZD2_k127_3955612_5 - - - - 0.000000000000000000000000000000000000000000000000000000006892 209.0
GZD2_k127_3955612_6 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000004138 153.0
GZD2_k127_3955612_7 Cytochrome c, class I - - - 0.00005272 48.0
GZD2_k127_3969210_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 495.0
GZD2_k127_3969210_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000005334 274.0
GZD2_k127_39906_0 Domain of unknown function (DUF3400) - - - 0.0 1297.0
GZD2_k127_39906_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 301.0
GZD2_k127_4025145_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1301.0
GZD2_k127_4025145_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 442.0
GZD2_k127_4025145_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 351.0
GZD2_k127_4025145_3 Phosphoesterase family - - - 0.000000000000000000000000000000000006095 144.0
GZD2_k127_4025145_4 Putative quorum-sensing-regulated virulence factor K09954 - - 0.000000000000000000000000000000003984 129.0
GZD2_k127_4033423_0 Domain of unknown function (DUF3471) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 591.0
GZD2_k127_4033423_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000007364 180.0
GZD2_k127_4033423_2 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000444 88.0
GZD2_k127_4059449_0 Alkyl hydroperoxide reductase K03387 - - 0.0000000000000000000000000000000000000000000000000001422 206.0
GZD2_k127_4059449_1 Transporter associated domain K06189 - - 0.0000000000000000000000000001987 115.0
GZD2_k127_4070435_0 Glutamine synthetase, catalytic domain K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 554.0
GZD2_k127_4070435_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 524.0
GZD2_k127_4070435_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001897 232.0
GZD2_k127_4077492_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 8.759e-231 726.0
GZD2_k127_4077492_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 597.0
GZD2_k127_4077492_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976 - - 0.0000000000000000000001988 104.0
GZD2_k127_4077492_2 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 601.0
GZD2_k127_4077492_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 420.0
GZD2_k127_4077492_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 335.0
GZD2_k127_4077492_5 PFAM Peptidase S24 S26A S26B, conserved region K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 324.0
GZD2_k127_4077492_6 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 329.0
GZD2_k127_4077492_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000002438 163.0
GZD2_k127_4077492_8 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000005605 164.0
GZD2_k127_4077492_9 Belongs to the ompA family K03286 - - 0.00000000000000000000000000046 121.0
GZD2_k127_4098173_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1214.0
GZD2_k127_4098173_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1159.0
GZD2_k127_4098173_10 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000000001568 160.0
GZD2_k127_4098173_12 Carbohydrate kinase - - - 0.00000009216 58.0
GZD2_k127_4098173_2 Participates in both transcription termination and antitermination K02600 - - 3.036e-270 836.0
GZD2_k127_4098173_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.659e-210 665.0
GZD2_k127_4098173_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 385.0
GZD2_k127_4098173_5 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 396.0
GZD2_k127_4098173_6 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 288.0
GZD2_k127_4098173_7 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003262 240.0
GZD2_k127_4098173_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000000000000002372 206.0
GZD2_k127_4098173_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000003412 177.0
GZD2_k127_4112088_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 433.0
GZD2_k127_4112088_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000000001868 188.0
GZD2_k127_4112088_2 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000001527 160.0
GZD2_k127_4112088_3 Uncharacterized ACR, COG1993 - - - 0.00000000000000000000000000000001368 129.0
GZD2_k127_4116173_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 462.0
GZD2_k127_4116173_1 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000001802 53.0
GZD2_k127_4119338_0 NeuB family K03856 - 2.5.1.54 1.701e-197 617.0
GZD2_k127_4119338_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 586.0
GZD2_k127_4119338_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 562.0
GZD2_k127_4119338_3 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 516.0
GZD2_k127_4119338_4 OsmC-like protein - - - 0.00000000000000000000000000000000000001768 148.0
GZD2_k127_4123391_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 374.0
GZD2_k127_4123391_1 Ribosomal protein L9, N-terminal domain K02939 - - 0.0000000000000000000000000000000000000000000000000000000000008484 214.0
GZD2_k127_4123391_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000919 153.0
GZD2_k127_4123391_3 DNA replication, synthesis of RNA primer K02686 - - 0.000000000000000000000000000009566 121.0
GZD2_k127_4123391_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000001373 71.0
GZD2_k127_4129030_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1336.0
GZD2_k127_4129030_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 1.395e-204 645.0
GZD2_k127_4129030_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000004862 250.0
GZD2_k127_4129030_11 bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001189 243.0
GZD2_k127_4129030_12 RimK-like ATPgrasp N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001043 232.0
GZD2_k127_4129030_13 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001071 214.0
GZD2_k127_4129030_14 TIGRFAM alkylphosphonate utilization operon protein PhnA K06193 - - 0.0000000000000000000000000000000000000000000000000000000002403 204.0
GZD2_k127_4129030_15 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000002191 190.0
GZD2_k127_4129030_16 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000000000000001473 158.0
GZD2_k127_4129030_17 BON domain - - - 0.0000000000000000000000000001193 123.0
GZD2_k127_4129030_19 (ABC) transporter - - - 0.000001079 59.0
GZD2_k127_4129030_2 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 623.0
GZD2_k127_4129030_3 Sigma-54 interaction domain K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 548.0
GZD2_k127_4129030_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 500.0
GZD2_k127_4129030_5 histidine kinase HAMP region domain protein K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 465.0
GZD2_k127_4129030_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 447.0
GZD2_k127_4129030_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 381.0
GZD2_k127_4129030_8 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 318.0
GZD2_k127_4129030_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 291.0
GZD2_k127_4156909_0 Signal transduction histidine kinase, phosphotransfer (Hpt) region K13490 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 607.0
GZD2_k127_4156909_1 chemotaxis, protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 383.0
GZD2_k127_4156909_2 - - - - 0.000000000000000000001395 101.0
GZD2_k127_4156909_3 Type II secretion system protein G K02456 - - 0.000000000000000000005188 94.0
GZD2_k127_4157823_0 SMART Tetratricopeptide domain protein - - - 1.201e-210 681.0
GZD2_k127_4157823_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 556.0
GZD2_k127_4157823_10 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000007015 229.0
GZD2_k127_4157823_11 - - - - 0.000000000000000000000000000000000000000000000000000000000001819 215.0
GZD2_k127_4157823_12 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000001965 214.0
GZD2_k127_4157823_13 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000002247 199.0
GZD2_k127_4157823_14 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000002684 190.0
GZD2_k127_4157823_15 - - - - 0.0000000000000000000000001156 109.0
GZD2_k127_4157823_16 PAS domain - - - 0.00000000000001151 83.0
GZD2_k127_4157823_17 Copper resistance protein K07156 - - 0.00000000001439 73.0
GZD2_k127_4157823_18 response regulator K13041 - - 0.0000000006164 68.0
GZD2_k127_4157823_19 - - - - 0.00000001133 61.0
GZD2_k127_4157823_2 Diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 523.0
GZD2_k127_4157823_3 Periplasmic binding protein LacI transcriptional regulator K11930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 431.0
GZD2_k127_4157823_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 356.0
GZD2_k127_4157823_5 Histidine kinase K20975 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000108 314.0
GZD2_k127_4157823_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005843 271.0
GZD2_k127_4157823_7 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001368 256.0
GZD2_k127_4157823_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001534 241.0
GZD2_k127_4157823_9 CHASE - - - 0.000000000000000000000000000000000000000000000000000000000000000004778 256.0
GZD2_k127_4160129_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 453.0
GZD2_k127_4160129_1 ASPIC and UnbV - - - 0.00000000000000000000000004027 111.0
GZD2_k127_4160689_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 2.025e-264 825.0
GZD2_k127_4160689_1 Major Facilitator Superfamily K08227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 453.0
GZD2_k127_4169586_0 Protein of unknown function (DUF3095) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 303.0
GZD2_k127_4169586_1 HWE histidine kinase - - - 0.00000000000000000000000000000000001276 143.0
GZD2_k127_4191535_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 481.0
GZD2_k127_4191535_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 364.0
GZD2_k127_4191535_2 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002894 282.0
GZD2_k127_4191535_3 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001974 240.0
GZD2_k127_4191535_4 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000002465 170.0
GZD2_k127_4191535_5 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000006376 117.0
GZD2_k127_4238255_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1099.0
GZD2_k127_4238255_1 Sulfate permease family K03321 - - 5.699e-236 741.0
GZD2_k127_4238255_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 318.0
GZD2_k127_4238255_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 291.0
GZD2_k127_4238255_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002176 267.0
GZD2_k127_4238255_5 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000000000002056 118.0
GZD2_k127_4238255_6 - - - - 0.0000000000000000000002154 102.0
GZD2_k127_4242905_0 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 417.0
GZD2_k127_4242905_1 Peptidase M15A K03791 - - 0.000000000000000000000000003956 119.0
GZD2_k127_4242905_2 - - - - 0.00000000000000000007041 103.0
GZD2_k127_4242905_4 cellulase activity - - - 0.00006296 55.0
GZD2_k127_4247284_0 protein conserved in bacteria K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 531.0
GZD2_k127_4247284_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 452.0
GZD2_k127_4247284_2 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003817 277.0
GZD2_k127_4247284_3 methyltransferase - - - 0.0000000000000000000000000000000000000003955 156.0
GZD2_k127_4247284_4 DsrC like protein K11179 - - 0.000000000000000000000000000007146 123.0
GZD2_k127_4247284_5 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000004372 59.0
GZD2_k127_4247284_6 - - - - 0.0002837 50.0
GZD2_k127_4252738_0 Nitroreductase family K02303,K04719 - 1.13.11.79,2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 299.0
GZD2_k127_4252738_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008113 272.0
GZD2_k127_4252738_2 OmpA family K03640 - - 0.000000000000000000000000000000000000000000000000000625 189.0
GZD2_k127_4255441_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 3.362e-226 713.0
GZD2_k127_4255441_1 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 2.238e-217 677.0
GZD2_k127_4255441_2 Belongs to the DegT DnrJ EryC1 family - - - 6.956e-205 653.0
GZD2_k127_4255441_3 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 567.0
GZD2_k127_4255441_4 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 536.0
GZD2_k127_4255441_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 318.0
GZD2_k127_4255441_6 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000000000000000001757 184.0
GZD2_k127_4255441_7 Cyclic nucleotide-monophosphate binding domain - - - 0.0000002753 52.0
GZD2_k127_426301_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000002442 185.0
GZD2_k127_426301_1 CYTH domain - - - 0.000000000000000000000000000000000000000000000000002542 190.0
GZD2_k127_426301_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000003863 186.0
GZD2_k127_426301_3 - - - - 0.0000000004463 62.0
GZD2_k127_4277395_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 2.967e-267 828.0
GZD2_k127_4277395_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 2.516e-254 800.0
GZD2_k127_4277395_2 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 554.0
GZD2_k127_4277395_3 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 417.0
GZD2_k127_4277395_4 Two component transcriptional regulator PhoB, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 387.0
GZD2_k127_4277395_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 376.0
GZD2_k127_4277395_6 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001134 274.0
GZD2_k127_4277395_7 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000001904 198.0
GZD2_k127_4277395_8 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000005592 73.0
GZD2_k127_4283780_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 8.675e-220 685.0
GZD2_k127_4283780_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 492.0
GZD2_k127_4283780_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 413.0
GZD2_k127_4283780_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001509 238.0
GZD2_k127_4283780_4 DNA polymerase X family K02347 - - 0.00000000000000000000000000000235 122.0
GZD2_k127_4295181_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.584e-273 842.0
GZD2_k127_4295181_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.136e-263 813.0
GZD2_k127_4295181_10 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000000000004862 134.0
GZD2_k127_4295181_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 535.0
GZD2_k127_4295181_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 522.0
GZD2_k127_4295181_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 407.0
GZD2_k127_4295181_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 374.0
GZD2_k127_4295181_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 320.0
GZD2_k127_4295181_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 300.0
GZD2_k127_4295181_8 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001946 261.0
GZD2_k127_4295181_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001543 215.0
GZD2_k127_429587_0 AP endonuclease family 2 C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 494.0
GZD2_k127_429587_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 342.0
GZD2_k127_429587_2 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006971 261.0
GZD2_k127_4319167_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 499.0
GZD2_k127_4319167_1 Histidine kinase K20975 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 404.0
GZD2_k127_4319167_2 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 337.0
GZD2_k127_4319167_4 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0002699 44.0
GZD2_k127_4321997_0 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 4.657e-247 765.0
GZD2_k127_4321997_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.056e-238 741.0
GZD2_k127_4321997_2 Homoserine dehydrogenase K00003 - 1.1.1.3 7.582e-238 741.0
GZD2_k127_4321997_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 1.941e-236 748.0
GZD2_k127_4321997_4 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 512.0
GZD2_k127_4321997_5 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 396.0
GZD2_k127_4321997_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 342.0
GZD2_k127_4321997_7 Threonine synthase N terminus K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 329.0
GZD2_k127_4321997_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005978 274.0
GZD2_k127_4321997_9 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000000009306 168.0
GZD2_k127_4329397_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.675e-241 757.0
GZD2_k127_4329397_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.485e-237 741.0
GZD2_k127_4329397_2 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 576.0
GZD2_k127_4329397_3 OmpA-like transmembrane domain K03286 - - 0.0000000000000000000000000309 114.0
GZD2_k127_4329397_4 Hemerythrin HHE cation binding domain - - - 0.00000000000000002917 91.0
GZD2_k127_4364181_0 Collagenase K08303 - - 2.019e-280 874.0
GZD2_k127_4364181_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 532.0
GZD2_k127_4364181_2 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000000000000000000000000003131 161.0
GZD2_k127_4364181_3 SlyX K03745 - - 0.00000000000000001955 86.0
GZD2_k127_4364181_4 - - - - 0.000000000000000466 85.0
GZD2_k127_4364181_5 - - - - 0.00000000000006437 78.0
GZD2_k127_4371940_0 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 359.0
GZD2_k127_4371940_1 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004538 267.0
GZD2_k127_4371940_2 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000921 173.0
GZD2_k127_4373957_0 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 480.0
GZD2_k127_4373957_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 258.0
GZD2_k127_4373957_2 RecX family K03565 - - 0.000000000000000000000000000000000000000000000000000000000006774 210.0
GZD2_k127_4378385_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.042e-243 755.0
GZD2_k127_4378385_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 585.0
GZD2_k127_4378385_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 490.0
GZD2_k127_4378385_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 441.0
GZD2_k127_4378385_4 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000948 270.0
GZD2_k127_4378385_5 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000004005 86.0
GZD2_k127_4382773_0 PFAM polysaccharide biosynthesis protein CapD - - - 5.954e-290 900.0
GZD2_k127_4382773_1 PFAM Glycosyl transferase, family 4, conserved region K13007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003028 243.0
GZD2_k127_4382773_2 Methyltransferase domain - - - 0.00000000000000009294 91.0
GZD2_k127_4386100_0 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 485.0
GZD2_k127_4386100_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 323.0
GZD2_k127_4386100_2 Nicotinamidase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000156 244.0
GZD2_k127_4399069_0 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003777 262.0
GZD2_k127_440272_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 395.0
GZD2_k127_440272_1 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000004285 224.0
GZD2_k127_440272_2 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000008142 185.0
GZD2_k127_4412781_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1077.0
GZD2_k127_4412781_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 361.0
GZD2_k127_4412781_2 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000000000006488 154.0
GZD2_k127_4415801_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 9.107e-220 692.0
GZD2_k127_4415801_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 563.0
GZD2_k127_4415801_2 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 292.0
GZD2_k127_4415801_3 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000001202 211.0
GZD2_k127_4415801_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000001435 175.0
GZD2_k127_4415801_5 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000000001615 180.0
GZD2_k127_4415801_6 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000001752 154.0
GZD2_k127_4460_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1089.0
GZD2_k127_4460_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 370.0
GZD2_k127_4460_2 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001111 293.0
GZD2_k127_4460_3 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002372 256.0
GZD2_k127_4460_4 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003799 250.0
GZD2_k127_450019_0 Thiolase, C-terminal domain K00632 - 2.3.1.16 1.769e-217 681.0
GZD2_k127_450019_1 COG0501 Zn-dependent protease with chaperone function - - - 0.0000000000000000000000002933 116.0
GZD2_k127_462100_0 PFAM ABC transporter related K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 496.0
GZD2_k127_462100_1 SMART band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 474.0
GZD2_k127_462100_2 PFAM secretion protein HlyD family protein K01993,K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 398.0
GZD2_k127_462100_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 342.0
GZD2_k127_462100_4 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000000000000000002615 139.0
GZD2_k127_4626347_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 545.0
GZD2_k127_4626347_1 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 413.0
GZD2_k127_4632542_0 Peptidase dimerisation domain K01270 - - 1.214e-214 676.0
GZD2_k127_4632542_1 Putative diguanylate phosphodiesterase - - - 0.0000001263 62.0
GZD2_k127_4671096_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.954e-223 698.0
GZD2_k127_4671096_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 375.0
GZD2_k127_4671096_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000005304 250.0
GZD2_k127_4671096_3 Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K10012 - 2.4.2.53 0.00000000000000000000000000001964 118.0
GZD2_k127_467697_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 3.448e-194 608.0
GZD2_k127_467697_1 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000397 226.0
GZD2_k127_4719333_0 CHASE2 K01768 - 4.6.1.1 3.474e-223 704.0
GZD2_k127_4719333_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 394.0
GZD2_k127_4719333_2 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000238 159.0
GZD2_k127_4788556_0 MgsA AAA+ ATPase C terminal K07478 - - 1.774e-236 744.0
GZD2_k127_4788556_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.96e-234 728.0
GZD2_k127_4788556_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000232 276.0
GZD2_k127_4788556_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002354 247.0
GZD2_k127_483142_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 430.0
GZD2_k127_483142_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 342.0
GZD2_k127_483142_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 338.0
GZD2_k127_483142_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 312.0
GZD2_k127_483142_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003925 269.0
GZD2_k127_483142_5 - - - - 0.000000000000000005189 87.0
GZD2_k127_4841453_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.223e-195 610.0
GZD2_k127_4841453_1 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 418.0
GZD2_k127_4841453_2 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000000000000000000000000009785 204.0
GZD2_k127_4920788_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.338e-218 683.0
GZD2_k127_4920788_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 598.0
GZD2_k127_4920788_2 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 381.0
GZD2_k127_4921325_0 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 615.0
GZD2_k127_4921325_1 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000007376 214.0
GZD2_k127_4926348_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1172.0
GZD2_k127_4926348_1 Belongs to the peptidase S16 family - - - 5.555e-287 903.0
GZD2_k127_4926348_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 454.0
GZD2_k127_4926348_3 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 400.0
GZD2_k127_4926348_4 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000005057 199.0
GZD2_k127_4926348_5 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000006958 227.0
GZD2_k127_492800_0 Neisseria PilC beta-propeller domain K02674 - - 0.0 1147.0
GZD2_k127_492800_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 372.0
GZD2_k127_492800_2 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002969 269.0
GZD2_k127_492800_3 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000000000000000001129 157.0
GZD2_k127_492800_4 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000199 149.0
GZD2_k127_492800_5 Sugar (and other) transporter - - - 0.0000000000000000000000000000165 118.0
GZD2_k127_492800_6 Type II transport protein GspH K08084 - - 0.000000000000000000000000002662 125.0
GZD2_k127_492800_7 type IV pilus modification protein PilV K02671 - - 0.00000000000000000000002816 105.0
GZD2_k127_4928001_0 Mur ligase family, catalytic domain K01924 - 6.3.2.8 1.891e-235 736.0
GZD2_k127_4928001_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 619.0
GZD2_k127_4928001_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 544.0
GZD2_k127_4928001_3 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 500.0
GZD2_k127_4928001_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 458.0
GZD2_k127_4928001_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 402.0
GZD2_k127_4928001_6 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 414.0
GZD2_k127_4928001_7 POTRA domain, FtsQ-type - - - 0.0000000000000000000000000000000000000000000000008602 183.0
GZD2_k127_4941634_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 398.0
GZD2_k127_4941634_1 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000749 203.0
GZD2_k127_4941634_2 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000000000001107 168.0
GZD2_k127_4941634_3 Bacterial regulatory protein, arsR family - - - 0.00000000005044 64.0
GZD2_k127_4958752_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1509.0
GZD2_k127_4958752_1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.0 1214.0
GZD2_k127_4958752_10 Threonine synthase N terminus K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 316.0
GZD2_k127_4958752_11 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 308.0
GZD2_k127_4958752_12 Transcriptional regulator K13641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 310.0
GZD2_k127_4958752_13 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 308.0
GZD2_k127_4958752_14 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 305.0
GZD2_k127_4958752_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000003067 235.0
GZD2_k127_4958752_16 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000004651 125.0
GZD2_k127_4958752_18 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000003556 81.0
GZD2_k127_4958752_2 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 4.408e-252 784.0
GZD2_k127_4958752_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.246e-246 775.0
GZD2_k127_4958752_4 kinase activity - - - 9.998e-202 636.0
GZD2_k127_4958752_5 glycolate oxidase iron-sulfur subunit K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 518.0
GZD2_k127_4958752_6 PFAM FAD linked oxidase domain protein K00104,K11472 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 452.0
GZD2_k127_4958752_7 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 408.0
GZD2_k127_4958752_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 379.0
GZD2_k127_4958752_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 358.0
GZD2_k127_4965786_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 522.0
GZD2_k127_4965786_1 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 471.0
GZD2_k127_4965786_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 467.0
GZD2_k127_4965786_3 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 355.0
GZD2_k127_4965786_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 346.0
GZD2_k127_4965786_5 Universal stress protein family - - - 0.00000000000000000000000000000000000000000001033 170.0
GZD2_k127_4965786_6 Prokaryotic cytochrome b561 K12262 - - 0.0000002535 56.0
GZD2_k127_4968524_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0 1210.0
GZD2_k127_4968524_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 9.636e-285 885.0
GZD2_k127_4968524_10 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 425.0
GZD2_k127_4968524_11 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 391.0
GZD2_k127_4968524_12 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 327.0
GZD2_k127_4968524_13 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 303.0
GZD2_k127_4968524_14 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001551 259.0
GZD2_k127_4968524_15 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000001999 234.0
GZD2_k127_4968524_16 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000000000008755 199.0
GZD2_k127_4968524_17 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000004681 166.0
GZD2_k127_4968524_18 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000003859 119.0
GZD2_k127_4968524_19 antisigma factor binding K04749 - - 0.000000000000000000000002822 106.0
GZD2_k127_4968524_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 1.388e-201 641.0
GZD2_k127_4968524_20 Histidine kinase-like ATPase domain - - - 0.000000000000000000000004216 118.0
GZD2_k127_4968524_21 antisigma factor binding K04749 - - 0.0000000000000000002023 93.0
GZD2_k127_4968524_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 529.0
GZD2_k127_4968524_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 528.0
GZD2_k127_4968524_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 485.0
GZD2_k127_4968524_6 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 467.0
GZD2_k127_4968524_7 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 421.0
GZD2_k127_4968524_8 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 419.0
GZD2_k127_4968524_9 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 421.0
GZD2_k127_4978810_0 HELICc2 K03722 - 3.6.4.12 2.581e-269 839.0
GZD2_k127_4978810_1 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000000002886 202.0
GZD2_k127_4987864_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 355.0
GZD2_k127_4987864_1 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 300.0
GZD2_k127_4987864_2 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000003311 231.0
GZD2_k127_4987864_3 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000007662 190.0
GZD2_k127_4994337_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1159.0
GZD2_k127_4994337_1 Chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 557.0
GZD2_k127_4994337_2 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000009992 246.0
GZD2_k127_4994337_3 Pfam Ankyrin K10799 - 2.4.2.30 0.0001105 50.0
GZD2_k127_5010326_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 7.595e-319 990.0
GZD2_k127_5010326_1 cellulose synthase K00694 - 2.4.1.12 1.247e-265 850.0
GZD2_k127_5010326_10 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000004735 265.0
GZD2_k127_5010326_11 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006424 243.0
GZD2_k127_5010326_12 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000003196 187.0
GZD2_k127_5010326_13 chlorophyll binding - - - 0.00000000000000000000000000000000004156 152.0
GZD2_k127_5010326_14 Sulfurtransferase TusA K04085 - - 0.000000000000000000000000007485 111.0
GZD2_k127_5010326_15 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000005855 65.0
GZD2_k127_5010326_2 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 585.0
GZD2_k127_5010326_3 cellulose synthase K20541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 561.0
GZD2_k127_5010326_4 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 443.0
GZD2_k127_5010326_5 Cellulose biosynthesis protein BcsG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 450.0
GZD2_k127_5010326_6 cellulose synthase operon C domain protein K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 384.0
GZD2_k127_5010326_7 Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 338.0
GZD2_k127_5010326_8 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 315.0
GZD2_k127_5010326_9 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003333 269.0
GZD2_k127_5020720_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 6.044e-239 740.0
GZD2_k127_5020720_1 Bacterial lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 447.0
GZD2_k127_5020720_2 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 346.0
GZD2_k127_5020720_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 323.0
GZD2_k127_5031110_0 PAS S-box diguanylate cyclase domain-containing protein - - - 2.077e-231 766.0
GZD2_k127_5031110_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000278 179.0
GZD2_k127_5059971_0 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 575.0
GZD2_k127_5059971_1 4 iron, 4 sulfur cluster binding K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 514.0
GZD2_k127_5059971_2 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 375.0
GZD2_k127_5059971_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 291.0
GZD2_k127_5059971_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000006168 238.0
GZD2_k127_5059971_5 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000000008235 184.0
GZD2_k127_5059971_6 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000002156 169.0
GZD2_k127_5059971_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000009068 111.0
GZD2_k127_5059971_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000007824 95.0
GZD2_k127_5059971_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - 0.00000000002368 63.0
GZD2_k127_5072071_0 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 551.0
GZD2_k127_5072071_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000004826 215.0
GZD2_k127_5072071_2 beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000335 67.0
GZD2_k127_5079865_0 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 624.0
GZD2_k127_5079865_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 584.0
GZD2_k127_5079865_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 567.0
GZD2_k127_5079865_3 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004583 268.0
GZD2_k127_5079865_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000006067 113.0
GZD2_k127_5079865_5 HNH endonuclease - - - 0.00000000000000000001835 95.0
GZD2_k127_5079865_6 Ribonuclease P K03536 - 3.1.26.5 0.000000000000000001512 91.0
GZD2_k127_5079865_7 Zn-ribbon-containing protein involved in phosphonate metabolism K06193 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000001883 81.0
GZD2_k127_5079865_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000001204 79.0
GZD2_k127_5105306_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 379.0
GZD2_k127_5105306_1 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000004834 134.0
GZD2_k127_5148953_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 522.0
GZD2_k127_5148953_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 521.0
GZD2_k127_5148953_2 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 513.0
GZD2_k127_5148953_3 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 360.0
GZD2_k127_5148953_4 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
GZD2_k127_5148953_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000000003867 188.0
GZD2_k127_5148953_6 - - - - 0.0000000000000000000669 95.0
GZD2_k127_5148953_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000005563 83.0
GZD2_k127_5157988_0 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 293.0
GZD2_k127_5157988_1 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001004 262.0
GZD2_k127_5157988_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000002967 232.0
GZD2_k127_5157988_3 Universal stress protein family - - - 0.00000000000000000000000000000272 129.0
GZD2_k127_516214_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 575.0
GZD2_k127_516214_1 PFAM CHAD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 502.0
GZD2_k127_516214_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 326.0
GZD2_k127_516214_3 extracellular alpha-helical protein K06894 - - 0.0000001454 55.0
GZD2_k127_5167086_0 histidine kinase HAMP region domain protein K02660,K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 492.0
GZD2_k127_5167086_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 334.0
GZD2_k127_5167086_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 292.0
GZD2_k127_5167086_3 Phytochelatin synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001084 271.0
GZD2_k127_5167086_4 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000181 216.0
GZD2_k127_5167086_5 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000000000009928 203.0
GZD2_k127_5167086_6 Two component signalling adaptor domain K02659 - - 0.0000000000000000000000000000000000000000000000000000004627 197.0
GZD2_k127_5167086_7 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000000006361 115.0
GZD2_k127_517480_0 Amidase K01426 - 3.5.1.4 4.576e-203 645.0
GZD2_k127_517480_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000005788 69.0
GZD2_k127_5178964_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 600.0
GZD2_k127_5178964_1 Sigma-70 factor, region 1.2 K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 413.0
GZD2_k127_5178964_10 LPP20 lipoprotein - - - 0.000000000000000000000000000000000000000000000001729 188.0
GZD2_k127_5178964_11 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000008246 156.0
GZD2_k127_5178964_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000002068 165.0
GZD2_k127_5178964_13 LPP20 lipoprotein - - - 0.0000000000000000000000000000000007324 142.0
GZD2_k127_5178964_2 SMART HTH transcriptional regulator, Crp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 339.0
GZD2_k127_5178964_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 325.0
GZD2_k127_5178964_4 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 322.0
GZD2_k127_5178964_5 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 327.0
GZD2_k127_5178964_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000006929 257.0
GZD2_k127_5178964_7 Peptidoglycan-synthase activator LpoB K07337 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000316 246.0
GZD2_k127_5178964_8 E-Z type HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000001913 202.0
GZD2_k127_5178964_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000004577 189.0
GZD2_k127_5183451_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 506.0
GZD2_k127_5183451_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 322.0
GZD2_k127_5189463_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1671.0
GZD2_k127_5189463_1 PFAM peptidase M17 leucyl aminopeptidase domain protein K01255 - 3.4.11.1 1.29e-241 753.0
GZD2_k127_5189463_10 Bacterial SH3 domain - - - 0.00000000000000000000000000000000001664 145.0
GZD2_k127_5189463_11 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000007266 136.0
GZD2_k127_5189463_12 Histidine kinase - - - 0.00000000000000000000000000000000007871 143.0
GZD2_k127_5189463_13 PFAM Rhodanese-like K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000006184 129.0
GZD2_k127_5189463_14 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000008672 114.0
GZD2_k127_5189463_15 Sel1-like repeats. K07126 - - 0.00000000000001423 81.0
GZD2_k127_5189463_2 Virulence factor membrane-bound polymerase, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 571.0
GZD2_k127_5189463_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 512.0
GZD2_k127_5189463_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 437.0
GZD2_k127_5189463_5 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 433.0
GZD2_k127_5189463_6 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 302.0
GZD2_k127_5189463_7 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000462 257.0
GZD2_k127_5189463_8 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000007869 236.0
GZD2_k127_5189463_9 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000003084 191.0
GZD2_k127_5194325_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 5.693e-278 877.0
GZD2_k127_5194325_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 516.0
GZD2_k127_5194325_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 326.0
GZD2_k127_5194325_3 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 318.0
GZD2_k127_5194325_4 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 309.0
GZD2_k127_5194325_5 rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005311 249.0
GZD2_k127_5194325_6 membrane protein domain - - - 0.000000000000000000000000000000000001352 151.0
GZD2_k127_5194325_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000009991 72.0
GZD2_k127_5212007_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1367.0
GZD2_k127_5212007_1 PFAM Isocitrate dehydrogenase NADP-dependent monomeric type K00031 - 1.1.1.42 0.0 1209.0
GZD2_k127_5212007_10 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000003552 162.0
GZD2_k127_5212007_11 SMART Cold shock protein K03704 - - 0.00000000000000000000000000000000006324 136.0
GZD2_k127_5212007_12 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000002139 127.0
GZD2_k127_5212007_13 - - - - 0.0000000000001043 74.0
GZD2_k127_5212007_14 Putative zinc- or iron-chelating domain - - - 0.00000001276 63.0
GZD2_k127_5212007_2 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1151.0
GZD2_k127_5212007_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 596.0
GZD2_k127_5212007_4 PFAM Haloacid dehalogenase domain protein hydrolase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 450.0
GZD2_k127_5212007_5 Peptidase C13 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 464.0
GZD2_k127_5212007_6 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 306.0
GZD2_k127_5212007_7 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 301.0
GZD2_k127_5212007_8 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008783 276.0
GZD2_k127_5212007_9 - - - - 0.0000000000000000000000000000000000000000000003141 174.0
GZD2_k127_5245429_0 PFAM aminotransferase class I and II K14267 - 2.6.1.17 2.233e-213 668.0
GZD2_k127_5245429_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 4.913e-206 647.0
GZD2_k127_5245429_10 ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000004675 201.0
GZD2_k127_5245429_11 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000009565 199.0
GZD2_k127_5245429_12 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000001013 176.0
GZD2_k127_5245429_13 Domain of unknown function (DUF4149) - - - 0.000000000000000000000000000000000002091 143.0
GZD2_k127_5245429_2 PFAM type II secretion system protein E K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 554.0
GZD2_k127_5245429_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 531.0
GZD2_k127_5245429_4 Carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 526.0
GZD2_k127_5245429_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 328.0
GZD2_k127_5245429_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 323.0
GZD2_k127_5245429_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003141 280.0
GZD2_k127_5245429_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005169 274.0
GZD2_k127_5245429_9 Bacterial-like globin - - - 0.000000000000000000000000000000000000000000000000000000002375 202.0
GZD2_k127_5249291_0 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.00000000000000000000000000000000000000000000000003189 190.0
GZD2_k127_5249291_1 sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000005994 177.0
GZD2_k127_5249291_2 Psort location Cytoplasmic, score - - - 0.00000000000001207 74.0
GZD2_k127_5256442_0 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 5.248e-293 912.0
GZD2_k127_5256442_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.043e-232 732.0
GZD2_k127_5256442_2 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 478.0
GZD2_k127_5256442_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 357.0
GZD2_k127_5256442_4 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 309.0
GZD2_k127_5256442_5 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000002258 144.0
GZD2_k127_5274141_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.087e-267 827.0
GZD2_k127_5274141_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 396.0
GZD2_k127_5274141_2 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000003743 267.0
GZD2_k127_5279577_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001411 244.0
GZD2_k127_5279577_1 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000000000000000000000000000000000000000000000000005728 192.0
GZD2_k127_5279577_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000001512 147.0
GZD2_k127_5279577_3 - - - - 0.00000000000000008277 89.0
GZD2_k127_5306986_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 9.689e-236 734.0
GZD2_k127_5306986_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.598e-219 690.0
GZD2_k127_5306986_2 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000002516 94.0
GZD2_k127_5313592_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 6.129e-196 615.0
GZD2_k127_5313592_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 431.0
GZD2_k127_5313592_2 Bacterial-like globin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 338.0
GZD2_k127_5313592_3 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 334.0
GZD2_k127_5313592_4 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000000001196 203.0
GZD2_k127_5313592_5 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000000003351 201.0
GZD2_k127_5313592_6 GTP-binding domain protein K06945 - - 0.0000000000000000000000000000000000000000000000000003744 189.0
GZD2_k127_5313592_7 NADP transhydrogenase K00322,K00324 - 1.6.1.1,1.6.1.2 0.0000000000000000000000000000000000000000000000171 171.0
GZD2_k127_5313592_8 Roadblock/LC7 domain K07131 - - 0.0000000000000000000000000004226 118.0
GZD2_k127_5313592_9 - - - - 0.00000000000001673 81.0
GZD2_k127_5313829_0 cytochrome c peroxidase K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 476.0
GZD2_k127_5313829_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 461.0
GZD2_k127_5313829_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 400.0
GZD2_k127_5313829_3 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 341.0
GZD2_k127_5313829_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 316.0
GZD2_k127_5313829_5 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 296.0
GZD2_k127_5313829_6 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001247 248.0
GZD2_k127_5313829_7 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000003257 169.0
GZD2_k127_5313829_8 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000000000000000000000000000007808 145.0
GZD2_k127_5356294_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 5.886e-276 851.0
GZD2_k127_5356294_1 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003666 275.0
GZD2_k127_5356294_2 'Cold-shock' DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007197 224.0
GZD2_k127_5356294_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000009948 184.0
GZD2_k127_5356294_4 Protein of unknown function (DUF2846) - - - 0.0000000000000000000000000000000000000000003988 168.0
GZD2_k127_5356294_5 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000001255 141.0
GZD2_k127_5356294_6 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000467 145.0
GZD2_k127_5356294_7 Transposase IS200 like K07491 - - 0.00000000000000000000000000001286 118.0
GZD2_k127_5374364_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 287.0
GZD2_k127_5374364_1 Transcriptional regulatory protein, C terminal K07663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005919 282.0
GZD2_k127_5374364_2 Predicted integral membrane protein (DUF2269) - - - 0.0000000000000000000000000000000000000000000000000000000005803 211.0
GZD2_k127_5374364_3 DoxX-like family - - - 0.000000000000000000000000000000000001878 140.0
GZD2_k127_5374364_4 - - - - 0.000000000000000000000000000001256 124.0
GZD2_k127_539766_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 527.0
GZD2_k127_539766_1 SMART phosphoesterase PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 292.0
GZD2_k127_539766_2 DJ-1/PfpI family K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000001914 231.0
GZD2_k127_539766_3 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000744 208.0
GZD2_k127_539766_4 methyltransferase - - - 0.000000008854 62.0
GZD2_k127_5482378_0 Sugar (and other) transporter - - - 1.515e-204 647.0
GZD2_k127_5482378_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001855 263.0
GZD2_k127_5482378_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000001428 145.0
GZD2_k127_5482378_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000009574 136.0
GZD2_k127_5558393_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003996 291.0
GZD2_k127_5558393_1 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000009605 131.0
GZD2_k127_5558393_2 PFAM cytochrome c class I K08738 - - 0.00000000000000000002558 96.0
GZD2_k127_55662_0 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 2.083e-199 623.0
GZD2_k127_55662_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000254 214.0
GZD2_k127_5602534_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 568.0
GZD2_k127_5602534_1 S4 RNA-binding domain K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 411.0
GZD2_k127_5602534_2 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 375.0
GZD2_k127_5602534_3 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 285.0
GZD2_k127_5602534_4 PFAM type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000676 235.0
GZD2_k127_5602534_5 Dihydroneopterin aldolase - - - 0.0000000000000000000000000000000000000002672 154.0
GZD2_k127_5602534_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000000000001802 132.0
GZD2_k127_5616688_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 593.0
GZD2_k127_5616688_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 589.0
GZD2_k127_5616688_2 TIGRFAM succinate dehydrogenase, hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000000001279 153.0
GZD2_k127_5616688_3 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000001839 121.0
GZD2_k127_5676573_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1077.0
GZD2_k127_5676573_1 Amidohydrolase family K01465 - 3.5.2.3 9.935e-228 715.0
GZD2_k127_5676573_2 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 370.0
GZD2_k127_5676573_3 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000002199 224.0
GZD2_k127_5676573_4 Domain of unknown function (DUF4124) - - - 0.000000000000000000000003372 108.0
GZD2_k127_568529_0 PFAM Peptidase M18, aminopeptidase I K01267 - 3.4.11.21 1.141e-215 677.0
GZD2_k127_568529_1 - - - - 0.00000000000000000000000000000000000000000000000001198 185.0
GZD2_k127_568529_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000002258 149.0
GZD2_k127_568529_3 NYN domain - - - 0.000000000000000000000000000000000158 132.0
GZD2_k127_568529_4 Cold shock protein domain K03704 - - 0.0000000000000000000000000000000003092 134.0
GZD2_k127_568529_5 phosphinothricin N-acetyltransferase activity K03823,K18816 - 2.3.1.183,2.3.1.82 0.000000000000000000000000000002337 130.0
GZD2_k127_568529_6 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.000000002727 68.0
GZD2_k127_5747726_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.364e-312 982.0
GZD2_k127_5747726_1 Ammonium Transporter Family K03320,K06580 - - 3.582e-232 722.0
GZD2_k127_5747726_10 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479 - - 0.000000000000000000000000000000000000000000000000000000000000000000002806 241.0
GZD2_k127_5747726_11 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000009785 196.0
GZD2_k127_5747726_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000003379 158.0
GZD2_k127_5747726_2 metal-dependent phosphohydrolase HD sub domain K07814 - - 1.649e-203 645.0
GZD2_k127_5747726_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 402.0
GZD2_k127_5747726_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 351.0
GZD2_k127_5747726_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 335.0
GZD2_k127_5747726_6 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 291.0
GZD2_k127_5747726_7 molybdenum cofactor K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 290.0
GZD2_k127_5747726_8 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009054 269.0
GZD2_k127_5747726_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000002328 249.0
GZD2_k127_5758552_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 359.0
GZD2_k127_5758552_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000000000000000000005408 239.0
GZD2_k127_5758552_2 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000003481 206.0
GZD2_k127_5758552_3 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000002903 156.0
GZD2_k127_5758552_4 - - - - 0.0000000000000000000000000000000000001907 146.0
GZD2_k127_5758552_5 Protein of unknown function (DUF1289) - - - 0.000000000003393 74.0
GZD2_k127_5767152_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 482.0
GZD2_k127_5767152_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 320.0
GZD2_k127_5767152_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005312 270.0
GZD2_k127_5774357_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 7.573e-253 788.0
GZD2_k127_5774357_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000007983 159.0
GZD2_k127_5774357_2 PFAM cobalamin synthesis protein P47K K04652 - - 0.0000000000000000000000767 101.0
GZD2_k127_5782382_0 Domain of unknown function (DUF3400) - - - 0.0 1159.0
GZD2_k127_5782382_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000000000007535 224.0
GZD2_k127_5782382_2 Prokaryotic cytochrome b561 - - - 0.00001992 49.0
GZD2_k127_5798861_0 Peptidase family U32 C-terminal domain K08303 - - 3.864e-257 798.0
GZD2_k127_5798861_1 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 2.363e-220 703.0
GZD2_k127_5798861_10 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000001559 113.0
GZD2_k127_5798861_2 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 505.0
GZD2_k127_5798861_3 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 444.0
GZD2_k127_5798861_4 chlorophyll binding K02690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 381.0
GZD2_k127_5798861_5 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004418 276.0
GZD2_k127_5798861_6 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005695 264.0
GZD2_k127_5798861_7 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001867 244.0
GZD2_k127_5798861_8 Domain of unknown function (DUF386) - - - 0.0000000000000000000000000000000000000000000000000000000000006392 232.0
GZD2_k127_5798861_9 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000000000000000002581 175.0
GZD2_k127_5804337_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.324e-262 812.0
GZD2_k127_5804337_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000515 82.0
GZD2_k127_5837720_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1016.0
GZD2_k127_5837720_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.779e-229 713.0
GZD2_k127_5837720_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000002037 222.0
GZD2_k127_5837720_3 - - - - 0.00004945 50.0
GZD2_k127_5845773_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 4e-209 672.0
GZD2_k127_5845773_1 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000001838 190.0
GZD2_k127_5845773_2 - - - - 0.00000000000000000000000000000000000000009344 156.0
GZD2_k127_5845773_3 SlyX K03745 - - 0.00000000000000005824 83.0
GZD2_k127_5845773_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00002116 50.0
GZD2_k127_5845773_5 Domain of unknown function (DUF4124) - - - 0.0001 51.0
GZD2_k127_5845773_6 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0006156 49.0
GZD2_k127_5863081_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000001382 216.0
GZD2_k127_5863081_2 - - - - 0.00000000000001394 76.0
GZD2_k127_5872024_0 Pyridoxal-phosphate dependent enzyme K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 542.0
GZD2_k127_5872024_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 353.0
GZD2_k127_5872024_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003515 251.0
GZD2_k127_5874729_0 AAA domain K16898 - 3.6.4.12 0.0 1133.0
GZD2_k127_5874729_1 - - - - 0.0004662 49.0
GZD2_k127_5874729_2 Domain of unknown function (DUF4124) - - - 0.0005671 49.0
GZD2_k127_5877009_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 7.663e-206 644.0
GZD2_k127_5877009_1 Histidine kinase K11617 - 2.7.13.3 0.00000000000000000000000000000000000003119 156.0
GZD2_k127_5877009_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000001976 105.0
GZD2_k127_5877009_3 - - - - 0.000000000000000000000003974 106.0
GZD2_k127_5893458_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 522.0
GZD2_k127_5893458_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 433.0
GZD2_k127_5893458_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 308.0
GZD2_k127_5893458_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000005984 214.0
GZD2_k127_5893458_4 polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000004769 220.0
GZD2_k127_5893458_5 - - - - 0.00000000000000000000000000000000000000000000001119 178.0
GZD2_k127_5893458_6 - - - - 0.00000000000000000000000000000000663 133.0
GZD2_k127_5893458_7 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000001791 50.0
GZD2_k127_5893594_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.775e-242 760.0
GZD2_k127_5893594_1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 534.0
GZD2_k127_5893594_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 529.0
GZD2_k127_5893594_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 455.0
GZD2_k127_5893594_4 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 416.0
GZD2_k127_5893594_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 410.0
GZD2_k127_5893594_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 383.0
GZD2_k127_5893594_7 glycosyl - - - 0.00000000000000000000000000000000000000000000000000000006979 199.0
GZD2_k127_5893594_8 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000005302 161.0
GZD2_k127_5893594_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000003608 115.0
GZD2_k127_5910485_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 535.0
GZD2_k127_5910485_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008898 276.0
GZD2_k127_5910485_2 PQ loop repeat K15383 - - 0.000000000000000000000000001886 121.0
GZD2_k127_5910485_3 Phosphoglycerate mutase family - - - 0.0000000171 63.0
GZD2_k127_5917598_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 310.0
GZD2_k127_5917598_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001337 237.0
GZD2_k127_5963271_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.58e-300 929.0
GZD2_k127_5974867_0 PFAM ABC-1 domain protein K03688 - - 3.098e-195 615.0
GZD2_k127_5974867_1 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 344.0
GZD2_k127_5974867_2 PFAM AMMECR1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006165 233.0
GZD2_k127_5974867_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001579 220.0
GZD2_k127_5974867_4 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000008997 112.0
GZD2_k127_5983119_0 Belongs to the peptidase M16 family K07263 - - 6.81e-198 626.0
GZD2_k127_5983119_1 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 569.0
GZD2_k127_5983119_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 495.0
GZD2_k127_5983119_3 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 379.0
GZD2_k127_5983119_4 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 353.0
GZD2_k127_5983119_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 351.0
GZD2_k127_5983119_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000009541 262.0
GZD2_k127_5983119_7 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000001863 249.0
GZD2_k127_5983119_8 Oxidoreductase FAD-binding domain K14581 - 1.18.1.7 0.0000000000000000000000000000000000000000000000000000000003131 205.0
GZD2_k127_5983119_9 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000001094 165.0
GZD2_k127_5987416_0 Insulinase (Peptidase family M16) K07263 - - 6.4e-323 1013.0
GZD2_k127_5987416_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 316.0
GZD2_k127_5987416_2 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000000000000272 236.0
GZD2_k127_5987416_3 - - - - 0.00000000000000000000000001815 114.0
GZD2_k127_5987416_4 - - - - 0.00004127 47.0
GZD2_k127_5993953_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 444.0
GZD2_k127_5993953_1 of poly-gamma-glutamate biosynthesis (capsule formation) K07282 - - 0.00000000000000000000000002675 115.0
GZD2_k127_5993953_3 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0001414 53.0
GZD2_k127_6012208_0 Protoglobin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 396.0
GZD2_k127_6012379_0 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 1.639e-199 623.0
GZD2_k127_6012379_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 539.0
GZD2_k127_6012379_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 425.0
GZD2_k127_6012379_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 355.0
GZD2_k127_6012379_4 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 321.0
GZD2_k127_6012379_5 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 315.0
GZD2_k127_6012379_6 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001613 274.0
GZD2_k127_6012379_7 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 259.0
GZD2_k127_6012379_8 Domain of unknown function (DUF4124) - - - 0.000000000000000001824 94.0
GZD2_k127_6012379_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000006792 84.0
GZD2_k127_6027032_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 464.0
GZD2_k127_6027032_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 382.0
GZD2_k127_6027032_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003686 268.0
GZD2_k127_6027032_3 Cold shock protein domain K03704 - - 0.0000000000000000000000000000000001633 132.0
GZD2_k127_6027032_4 - - - - 0.000000000000000466 85.0
GZD2_k127_6037520_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 3.738e-235 732.0
GZD2_k127_6037520_1 Oxidoreductase FAD-binding domain protein K00523,K18248 - 1.17.1.1 8.332e-207 653.0
GZD2_k127_6037520_10 chemotaxis, protein - - - 0.00000000000000000000000000003128 130.0
GZD2_k127_6037520_11 CheW-like domain - - - 0.000000000000000000000000001772 119.0
GZD2_k127_6037520_12 transmembrane transport - - - 0.0000000000000000000000000581 121.0
GZD2_k127_6037520_13 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000003513 86.0
GZD2_k127_6037520_14 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000137 70.0
GZD2_k127_6037520_2 hydroxypyruvate reductase K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 554.0
GZD2_k127_6037520_3 glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 535.0
GZD2_k127_6037520_4 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 526.0
GZD2_k127_6037520_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000002978 235.0
GZD2_k127_6037520_6 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000005648 214.0
GZD2_k127_6037520_7 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000001076 199.0
GZD2_k127_6037520_8 Response regulator receiver K02658 - - 0.0000000000000000000000000000000000000000000000000001955 189.0
GZD2_k127_6037520_9 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000009566 162.0
GZD2_k127_6064992_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 487.0
GZD2_k127_6064992_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 343.0
GZD2_k127_6064992_2 Protein of unknown function (DUF3240) - - - 0.00000000000000000000000000000000000000000009154 162.0
GZD2_k127_6064992_3 PFAM ABC-1 domain protein K03688 - - 0.000000000000000000000004658 102.0
GZD2_k127_6065649_0 PFAM PhoH family protein K07175 - - 8.016e-228 721.0
GZD2_k127_6065649_1 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 572.0
GZD2_k127_6065649_10 BolA-like protein K05527 - - 0.000000000000000000000003489 110.0
GZD2_k127_6065649_2 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 557.0
GZD2_k127_6065649_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 306.0
GZD2_k127_6065649_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000005687 238.0
GZD2_k127_6065649_5 Belongs to the MsrB Met sulfoxide reductase family K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000001639 222.0
GZD2_k127_6065649_6 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000001428 218.0
GZD2_k127_6065649_7 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000003404 218.0
GZD2_k127_6065649_8 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000000000001471 190.0
GZD2_k127_6065649_9 YCII-related domain - - - 0.000000000000000000000000000000000004529 138.0
GZD2_k127_6120034_0 Hsp90 protein K04079 - - 0.0 1105.0
GZD2_k127_6120034_1 MacB-like periplasmic core domain K02004 - - 1.096e-195 617.0
GZD2_k127_6120034_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 517.0
GZD2_k127_6120034_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 496.0
GZD2_k127_6120034_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 398.0
GZD2_k127_6120034_5 Type II secretion system protein G K02456 - - 0.0000000000000000000001534 107.0
GZD2_k127_6124547_0 Cysteine-rich domain K21834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 594.0
GZD2_k127_6124547_1 NiFe/NiFeSe hydrogenase small subunit C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 522.0
GZD2_k127_6124547_2 nitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000001877 196.0
GZD2_k127_6124547_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000001679 100.0
GZD2_k127_6134455_0 PFAM PEGA domain - - - 0.00001241 59.0
GZD2_k127_6134455_1 Domain of unknown function (DUF4149) - - - 0.00004633 46.0
GZD2_k127_6198208_0 serine protease K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 588.0
GZD2_k127_6198208_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 469.0
GZD2_k127_6198208_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 428.0
GZD2_k127_6198208_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 359.0
GZD2_k127_6198208_4 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000001827 222.0
GZD2_k127_6198208_5 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000001513 153.0
GZD2_k127_6198208_6 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000004637 125.0
GZD2_k127_6198208_7 Trm112p-like protein K09791 - - 0.00000000000000008583 81.0
GZD2_k127_6204808_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.289e-241 753.0
GZD2_k127_6204808_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 3.466e-218 681.0
GZD2_k127_6204808_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 2.936e-194 610.0
GZD2_k127_6204808_3 PFAM Repeat of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 369.0
GZD2_k127_6204808_4 Competence-damaged protein K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000001689 216.0
GZD2_k127_6204808_5 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000002581 151.0
GZD2_k127_6204808_6 Sporulation related domain K03749 - - 0.00000000000006975 78.0
GZD2_k127_6204808_7 RecX family K03565 - - 0.000000009802 61.0
GZD2_k127_6227293_0 Domain of unknown function (DUF1926) K22451 - 2.4.1.25 2.772e-271 854.0
GZD2_k127_6227293_1 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 428.0
GZD2_k127_6227293_2 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 399.0
GZD2_k127_6227293_3 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 344.0
GZD2_k127_6227293_4 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008636 274.0
GZD2_k127_6258584_0 general secretion pathway protein D K02453 - - 1.419e-229 738.0
GZD2_k127_6258584_1 type II secretion system protein E K02454,K02652,K12276 - - 6.741e-228 715.0
GZD2_k127_6258584_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 523.0
GZD2_k127_6258584_3 PFAM Type II secretion system F domain K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 424.0
GZD2_k127_6258584_5 protein domain (DUF2202) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007578 246.0
GZD2_k127_6258584_6 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000001285 215.0
GZD2_k127_6258584_8 general secretion pathway protein K02457 - - 0.000002907 54.0
GZD2_k127_6304391_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 549.0
GZD2_k127_6304391_1 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 492.0
GZD2_k127_6304391_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 454.0
GZD2_k127_6304391_3 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 440.0
GZD2_k127_6304391_4 - K09004 - - 0.0000000000000000001865 94.0
GZD2_k127_6307642_0 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000002969 227.0
GZD2_k127_6307642_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000006866 220.0
GZD2_k127_6307642_2 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000001052 196.0
GZD2_k127_6307642_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000006123 108.0
GZD2_k127_6307642_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00009551 44.0
GZD2_k127_6309773_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 2.478e-213 682.0
GZD2_k127_6309773_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 610.0
GZD2_k127_6309773_10 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00003723 46.0
GZD2_k127_6309773_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 499.0
GZD2_k127_6309773_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 401.0
GZD2_k127_6309773_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 366.0
GZD2_k127_6309773_5 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 332.0
GZD2_k127_6309773_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 320.0
GZD2_k127_6309773_7 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 295.0
GZD2_k127_6309773_8 Protein of unknown function (DUF615) K09889 - - 0.0000000000000000000000000000000000000000000000000000000000001904 233.0
GZD2_k127_6309773_9 Soluble lytic murein transglycosylase L domain K08309 - - 0.0000000000000000000575 90.0
GZD2_k127_6332117_0 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 357.0
GZD2_k127_6332117_1 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 283.0
GZD2_k127_6332117_2 receptor K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000007819 211.0
GZD2_k127_6332117_3 Cell division protein ZapA K09888 - - 0.00000000000000000000000000000000000000000218 160.0
GZD2_k127_6332117_4 - - - - 0.0000000006523 62.0
GZD2_k127_6332117_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000009963 51.0
GZD2_k127_6405834_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001182 287.0
GZD2_k127_6405834_1 PFAM cytochrome c class I K08738 - - 0.0000000000000000000000000000000000461 136.0
GZD2_k127_6405834_2 - - - - 0.000752 48.0
GZD2_k127_643995_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1073.0
GZD2_k127_643995_1 PFAM cytochrome c class I K08738 - - 0.0000000000000000000000000000000000000000000000000001492 188.0
GZD2_k127_643995_2 PFAM cytochrome c class I K08738 - - 0.00000000000000000000000000005683 125.0
GZD2_k127_643995_3 Domain of unknown function DUF302 - - - 0.0000000000000000000000002176 106.0
GZD2_k127_6492863_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 542.0
GZD2_k127_6492863_1 Domain of unknown function (DUF1877) - - - 0.000000000000000000000000001113 126.0
GZD2_k127_6492863_2 CAAX protease self-immunity - - - 0.0000000000000000000000001453 114.0
GZD2_k127_6492863_3 - - - - 0.00000000000000000006486 91.0
GZD2_k127_6492863_6 - - - - 0.0002279 49.0
GZD2_k127_6496943_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1043.0
GZD2_k127_6496943_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 2.349e-292 918.0
GZD2_k127_6496943_2 Sugar (and other) transporter K03446 - - 7.221e-251 784.0
GZD2_k127_6496943_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 480.0
GZD2_k127_6496943_4 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 387.0
GZD2_k127_6496943_5 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
GZD2_k127_6496943_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000000002384 191.0
GZD2_k127_6496943_7 transcriptional - - - 0.000000000000000000000000000000000000000000009215 165.0
GZD2_k127_6499598_0 ABC transporter K02010,K02017,K11072 - 3.6.3.29,3.6.3.30,3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 514.0
GZD2_k127_6499598_1 Pfam Binding-protein-dependent transport systems inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 421.0
GZD2_k127_6499598_2 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 381.0
GZD2_k127_6499598_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000007654 233.0
GZD2_k127_6499598_4 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000121 231.0
GZD2_k127_6499598_5 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000001954 196.0
GZD2_k127_6509085_0 PFAM Transposase IS66 family K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 500.0
GZD2_k127_6521713_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 517.0
GZD2_k127_6521713_1 Histidine kinase K14978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 368.0
GZD2_k127_6537066_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004192 258.0
GZD2_k127_6537066_1 - - - - 0.000000000000008188 78.0
GZD2_k127_69297_0 SMC domain protein - - - 0.0 1339.0
GZD2_k127_69297_1 PFAM tRNA synthetase class II (D K and N) K04567 - 6.1.1.6 6.362e-281 869.0
GZD2_k127_69297_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 291.0
GZD2_k127_69297_3 - - - - 0.0000000000000000000000000000000000000000000000000007568 187.0
GZD2_k127_69297_4 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000001779 107.0
GZD2_k127_765105_0 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 586.0
GZD2_k127_765105_1 4 iron, 4 sulfur cluster binding K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 533.0
GZD2_k127_765105_2 PFAM sigma-54 factor interaction domain-containing protein K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 482.0
GZD2_k127_765105_3 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 333.0
GZD2_k127_765105_4 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000001879 208.0
GZD2_k127_765105_5 - - - - 0.000000000000000000000000000000000000000000001916 168.0
GZD2_k127_765105_6 - - - - 0.000000000000000000476 93.0
GZD2_k127_765105_7 - K06950 - - 0.00000000000000006683 83.0
GZD2_k127_79621_0 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 515.0
GZD2_k127_79621_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 326.0
GZD2_k127_79621_2 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000002432 186.0
GZD2_k127_847862_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1536.0
GZD2_k127_847862_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1196.0
GZD2_k127_847862_2 Protein of unknown function - - - 0.0 1087.0
GZD2_k127_847862_3 modulator of DNA gyrase K03568 - - 3.061e-239 754.0
GZD2_k127_847862_4 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 3.253e-230 717.0
GZD2_k127_847862_5 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 1.825e-207 649.0
GZD2_k127_847862_6 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 529.0
GZD2_k127_847862_7 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 460.0
GZD2_k127_847862_8 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000008839 193.0
GZD2_k127_847862_9 PFAM cytochrome c class I K08738 - - 0.000000000000000001135 92.0
GZD2_k127_855887_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0 1017.0
GZD2_k127_855887_1 Aminotransferase class-III K01845 - 5.4.3.8 3.937e-242 757.0
GZD2_k127_855887_10 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 344.0
GZD2_k127_855887_11 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 341.0
GZD2_k127_855887_12 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 311.0
GZD2_k127_855887_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001654 291.0
GZD2_k127_855887_14 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001844 259.0
GZD2_k127_855887_15 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000000000000000002107 225.0
GZD2_k127_855887_16 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000001272 221.0
GZD2_k127_855887_17 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000006152 195.0
GZD2_k127_855887_18 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000001387 161.0
GZD2_k127_855887_19 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.00000000000000006102 83.0
GZD2_k127_855887_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 3.373e-232 758.0
GZD2_k127_855887_3 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 1.293e-204 644.0
GZD2_k127_855887_4 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 596.0
GZD2_k127_855887_5 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 548.0
GZD2_k127_855887_6 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 544.0
GZD2_k127_855887_7 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 468.0
GZD2_k127_855887_8 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 471.0
GZD2_k127_855887_9 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 424.0
GZD2_k127_880029_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 492.0
GZD2_k127_880029_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 484.0
GZD2_k127_880029_2 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K22319 - 6.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 467.0
GZD2_k127_880029_3 Protein of unknown function (DUF3419) K13622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 405.0
GZD2_k127_880029_4 transferase activity, transferring acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003249 285.0
GZD2_k127_880029_5 dolichyl monophosphate biosynthetic process K00981,K18678 - 2.7.1.182,2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000001615 261.0
GZD2_k127_880029_6 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000001952 52.0
GZD2_k127_881122_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 3.825e-238 740.0
GZD2_k127_881122_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 461.0
GZD2_k127_881122_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 414.0
GZD2_k127_881122_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 323.0
GZD2_k127_881122_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000009982 256.0
GZD2_k127_881122_5 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009754 237.0
GZD2_k127_881122_6 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000000005975 213.0
GZD2_k127_881122_7 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000000000000000001876 213.0
GZD2_k127_881122_8 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000009677 188.0
GZD2_k127_911697_0 Outer membrane usher protein K07347 - - 1.963e-233 746.0
GZD2_k127_911697_1 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 317.0
GZD2_k127_911697_2 Spore Coat Protein U domain - - - 0.0000000000000000000000000000000000000000000000000008718 195.0
GZD2_k127_911697_3 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.00000000001849 66.0
GZD2_k127_912248_0 Histidine Phosphotransfer domain K02487,K06596 - - 1.843e-228 733.0
GZD2_k127_912248_1 histidine kinase HAMP region domain protein K02660,K03406 - - 0.00000000000000000000000000000000000000000000005876 171.0
GZD2_k127_913947_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.541e-267 837.0
GZD2_k127_913947_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.893e-256 804.0
GZD2_k127_913947_2 DNA polymerase X family K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 556.0
GZD2_k127_913947_3 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000001535 213.0
GZD2_k127_913947_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000004728 198.0
GZD2_k127_913947_5 PFAM Di-haem cytochrome c - - - 0.000000000000000000000000000000000000000001094 163.0
GZD2_k127_913947_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000000265 132.0
GZD2_k127_937978_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 599.0
GZD2_k127_937978_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 555.0
GZD2_k127_937978_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 565.0
GZD2_k127_937978_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 455.0
GZD2_k127_937978_4 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
GZD2_k127_937978_5 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000000000000000000000000000000000000000000000001543 192.0
GZD2_k127_937978_6 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000001072 108.0
GZD2_k127_942635_0 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 489.0
GZD2_k127_942635_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 302.0
GZD2_k127_942635_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000007895 190.0
GZD2_k127_942635_3 - - - - 0.00000000000000000000000000000000003368 145.0
GZD2_k127_942635_4 Protein of unknown function (DUF2782) - - - 0.00000000000000000000004163 98.0
GZD2_k127_951489_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.996e-314 968.0
GZD2_k127_951489_1 PFAM type II secretion system protein E K02670 - - 1.483e-204 640.0
GZD2_k127_951489_10 PFAM PEGA domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001124 239.0
GZD2_k127_951489_11 YGGT family K02221 - - 0.000000000000000000000000000000000000000000000000000001273 197.0
GZD2_k127_951489_12 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000000000000003859 176.0
GZD2_k127_951489_13 DUF167 K09131 - - 0.00000000000000000000000004045 108.0
GZD2_k127_951489_14 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000003579 105.0
GZD2_k127_951489_2 PFAM type II secretion system protein E K02669,K12203 - - 3.714e-195 623.0
GZD2_k127_951489_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 557.0
GZD2_k127_951489_4 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 371.0
GZD2_k127_951489_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 313.0
GZD2_k127_951489_6 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 303.0
GZD2_k127_951489_7 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002032 259.0
GZD2_k127_951489_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000001062 248.0
GZD2_k127_951489_9 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000001148 231.0