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Overview

ID MAG01607
Name HFD1_bin.10
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JAOUJD01
Species
Assembly information
Completeness (%) 70.53
Contamination (%) 1.66
GC content (%) 67.0
N50 (bp) 4,205
Genome size (bp) 2,544,094

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2709

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1013403_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 454.0
HFD1_k127_1013403_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 435.0
HFD1_k127_1014649_0 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 606.0
HFD1_k127_1014649_1 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000000000000000000000006704 151.0
HFD1_k127_1014649_2 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000001993 109.0
HFD1_k127_1051935_0 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 543.0
HFD1_k127_1051935_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 501.0
HFD1_k127_1051935_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 387.0
HFD1_k127_1051935_3 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 322.0
HFD1_k127_1051935_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 291.0
HFD1_k127_1053587_0 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000002615 215.0
HFD1_k127_1053587_1 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000005297 205.0
HFD1_k127_1053587_2 Uroporphyrinogen-III synthase HemD - - - 0.00000000000000000000000000003062 126.0
HFD1_k127_1053587_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000002905 93.0
HFD1_k127_1071981_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 295.0
HFD1_k127_1071981_1 oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000002592 234.0
HFD1_k127_1071981_2 oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000246 204.0
HFD1_k127_1071981_3 transporter component K07112 - - 0.0000000000000000000000002397 106.0
HFD1_k127_1082346_0 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002674 273.0
HFD1_k127_1082346_1 endoribonuclease K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000191 170.0
HFD1_k127_1082346_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000007921 57.0
HFD1_k127_108302_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1034.0
HFD1_k127_108302_1 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 460.0
HFD1_k127_108302_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 379.0
HFD1_k127_108302_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001255 277.0
HFD1_k127_108302_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 254.0
HFD1_k127_1095268_0 PFAM extracellular solute-binding protein family 1 K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 537.0
HFD1_k127_1095268_1 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 439.0
HFD1_k127_1095268_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 402.0
HFD1_k127_1095268_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 379.0
HFD1_k127_1095268_4 binding-protein-dependent transport systems inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 342.0
HFD1_k127_1095268_5 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000001045 192.0
HFD1_k127_1095268_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000002438 155.0
HFD1_k127_1108077_0 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 575.0
HFD1_k127_1108077_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 410.0
HFD1_k127_1108077_2 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000000000001561 220.0
HFD1_k127_1108077_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000001078 171.0
HFD1_k127_1108077_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.28 0.00000000000000000000000000000000006281 142.0
HFD1_k127_1129422_0 Sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 561.0
HFD1_k127_1129422_1 Rubrerythrin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002007 254.0
HFD1_k127_1131_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.999e-235 738.0
HFD1_k127_1131_1 Belongs to the GARS family K01945 - 6.3.4.13 1.166e-206 649.0
HFD1_k127_1131_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 471.0
HFD1_k127_1131_3 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 452.0
HFD1_k127_1131_4 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 362.0
HFD1_k127_1131_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000000000000001169 201.0
HFD1_k127_1131_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K01488 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 0.00000000000000000000000000004848 125.0
HFD1_k127_1131_7 Domain of unknown function (DUF2383) - - - 0.0000000000000000000004138 102.0
HFD1_k127_1143756_0 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 419.0
HFD1_k127_1143756_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 346.0
HFD1_k127_1143756_2 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K10002 - - 0.000000000007452 65.0
HFD1_k127_1148340_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1011.0
HFD1_k127_1148340_1 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 605.0
HFD1_k127_1148340_2 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 429.0
HFD1_k127_1148340_3 Iron-storage protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001797 238.0
HFD1_k127_1148340_4 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000003784 224.0
HFD1_k127_1148340_5 NlpC/P60 family K13695,K19303 - - 0.00000000000000000000000000000000000000000002138 168.0
HFD1_k127_1148340_6 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00360,K02192 - - 0.000000007942 59.0
HFD1_k127_1156769_0 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000403 233.0
HFD1_k127_1156769_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000003387 205.0
HFD1_k127_1156769_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000001094 150.0
HFD1_k127_1156769_3 Competence protein - - - 0.00000000000000000000000000004413 121.0
HFD1_k127_115991_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 588.0
HFD1_k127_115991_1 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 385.0
HFD1_k127_115991_2 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 370.0
HFD1_k127_115991_3 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 324.0
HFD1_k127_115991_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002132 250.0
HFD1_k127_115991_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009493 248.0
HFD1_k127_115991_6 PFAM DGPFAETKE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000148 215.0
HFD1_k127_115991_7 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000000002834 199.0
HFD1_k127_115991_8 YCII-related domain - - - 0.000000000000000000000000000000000000000006398 156.0
HFD1_k127_1176349_0 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 424.0
HFD1_k127_1176349_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000004641 147.0
HFD1_k127_1178260_0 FOG Transposase and inactivated derivatives K07495 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 484.0
HFD1_k127_1178260_1 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000001466 123.0
HFD1_k127_1180378_0 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 455.0
HFD1_k127_1180378_1 Alpha/beta hydrolase family - - - 0.00000001061 64.0
HFD1_k127_118307_0 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 394.0
HFD1_k127_118307_1 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000003968 244.0
HFD1_k127_118307_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000001625 203.0
HFD1_k127_118307_3 Acyl-ACP thioesterase - - - 0.0000000000000000000000000000000000002358 145.0
HFD1_k127_1187853_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 7.95e-209 660.0
HFD1_k127_1187853_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 537.0
HFD1_k127_1187853_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00003186 46.0
HFD1_k127_1197528_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 466.0
HFD1_k127_1197528_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000001731 257.0
HFD1_k127_1197528_2 nitrogen regulation protein NR(I) K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000001088 104.0
HFD1_k127_1199865_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 6.378e-305 951.0
HFD1_k127_1199865_1 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000001273 254.0
HFD1_k127_1199865_2 DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000002906 93.0
HFD1_k127_1215062_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.853e-215 677.0
HFD1_k127_1215062_1 Histidine kinase - - - 0.00000000000000000000000000001232 134.0
HFD1_k127_1225260_0 HupH hydrogenase expression protein, C-terminal conserved region K03618 - - 0.00000000000000000000000000000000000000000000000000000000000000000003839 241.0
HFD1_k127_1225260_1 Hydrogenase-1 expression protein HyaE K03619 - - 0.00000000000000000000000000000001099 138.0
HFD1_k127_1225260_2 HupF/HypC family K04653 - - 0.0000000000000000000004913 100.0
HFD1_k127_1240867_0 Pyridoxal-dependent decarboxylase K13745 - 4.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 577.0
HFD1_k127_1240867_1 s cog2930 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001025 259.0
HFD1_k127_1240867_2 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005864 250.0
HFD1_k127_1240867_3 - - - - 0.000000000000000000000000000000000000000000000007267 187.0
HFD1_k127_1240867_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000175 164.0
HFD1_k127_1240867_5 CoA binding domain K06929 - - 0.00000000000000000000000000000000000001625 150.0
HFD1_k127_1240867_6 Prokaryotic cytochrome b561 - - - 0.0000000000000000000176 93.0
HFD1_k127_1240867_7 - - - - 0.00000000000000000106 92.0
HFD1_k127_1240867_8 Carbohydrate binding module (family 6) - - - 0.00000000000425 74.0
HFD1_k127_1244331_0 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 410.0
HFD1_k127_1250587_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.39e-214 676.0
HFD1_k127_1250587_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 589.0
HFD1_k127_1250587_10 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000575 143.0
HFD1_k127_1250587_11 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000001624 119.0
HFD1_k127_1250587_12 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000003322 78.0
HFD1_k127_1250587_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 573.0
HFD1_k127_1250587_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 556.0
HFD1_k127_1250587_4 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 473.0
HFD1_k127_1250587_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 453.0
HFD1_k127_1250587_6 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 346.0
HFD1_k127_1250587_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 320.0
HFD1_k127_1250587_8 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001823 230.0
HFD1_k127_1250587_9 Tetratricopeptide repeat K02656 - - 0.000000000000000000000000000000000000000000000000000000000001188 218.0
HFD1_k127_125447_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 588.0
HFD1_k127_125447_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000001032 150.0
HFD1_k127_125447_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000002701 114.0
HFD1_k127_128208_0 serine-type aminopeptidase activity K02030,K14475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 323.0
HFD1_k127_128208_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008527 271.0
HFD1_k127_1320059_0 PFAM VanZ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001319 276.0
HFD1_k127_1320059_1 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000959 170.0
HFD1_k127_1320059_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000002495 150.0
HFD1_k127_1320059_3 PFAM Sporulation domain protein - - - 0.0000003744 57.0
HFD1_k127_1358052_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 2.996e-207 656.0
HFD1_k127_1365735_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 467.0
HFD1_k127_1365735_1 Dehydrogenase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 316.0
HFD1_k127_1367704_0 Bacterial pre-peptidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 531.0
HFD1_k127_1367704_1 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 303.0
HFD1_k127_1375699_0 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 321.0
HFD1_k127_1375699_1 Divalent heavy-metal cations transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
HFD1_k127_1405008_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 466.0
HFD1_k127_1405008_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001258 277.0
HFD1_k127_1405008_2 Domain of unknown function (DUF305) K08995 - - 0.0000000000000000000000000000000000000004637 158.0
HFD1_k127_140569_0 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 313.0
HFD1_k127_140569_1 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007126 263.0
HFD1_k127_140569_2 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000003554 143.0
HFD1_k127_144011_0 Transposase or inactivated derivative - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 432.0
HFD1_k127_144011_1 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000000000000000000000000003557 229.0
HFD1_k127_1545361_0 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 286.0
HFD1_k127_1545361_1 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001273 257.0
HFD1_k127_1545361_2 Pyridoxal-phosphate dependent enzyme K01505,K05396,K17950 - 3.5.99.7,4.4.1.15,4.4.1.25 0.00000000000000000000000000000000000000000000000000001754 190.0
HFD1_k127_1554826_0 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 611.0
HFD1_k127_1554826_1 Histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 291.0
HFD1_k127_1614818_0 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 390.0
HFD1_k127_1614818_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000003289 192.0
HFD1_k127_1614818_2 COG3291 FOG PKD repeat - - - 0.00002906 54.0
HFD1_k127_1622079_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 1.291e-217 681.0
HFD1_k127_1622079_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000399 185.0
HFD1_k127_1625133_0 cytochrome C peroxidase - - - 3.035e-195 630.0
HFD1_k127_1625133_1 Protein of unknown function (DUF4236) - - - 0.00000000000000001008 91.0
HFD1_k127_1625133_2 Protein of unknown function (DUF4236) - - - 0.00000000000000001727 95.0
HFD1_k127_1627242_0 CHAT domain - - - 0.0 1094.0
HFD1_k127_1627242_1 N-acetylmuramoyl-L-alanine amidase - - - 1.625e-226 711.0
HFD1_k127_1627242_2 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000335 212.0
HFD1_k127_1627242_3 - - - - 0.0000000000000000000000000000000000000000000000002803 190.0
HFD1_k127_1627242_4 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000004892 80.0
HFD1_k127_1644082_0 Peptidase family M3 K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 1.13e-198 637.0
HFD1_k127_1644082_1 membrane - - - 0.000000000000000000000000000001382 126.0
HFD1_k127_1645299_0 - - - - 0.00000000000000000006483 96.0
HFD1_k127_1645299_1 - - - - 0.00000000000000002482 91.0
HFD1_k127_1645299_2 - - - - 0.000000000001072 76.0
HFD1_k127_1645299_3 - - - - 0.0000000004135 69.0
HFD1_k127_1645665_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 609.0
HFD1_k127_1645665_1 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 474.0
HFD1_k127_1645665_2 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 417.0
HFD1_k127_1645665_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000408 189.0
HFD1_k127_1645665_4 PFAM HemY domain protein K02498 - - 0.00000000000001152 81.0
HFD1_k127_1656847_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 524.0
HFD1_k127_1656847_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 339.0
HFD1_k127_1656847_2 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 260.0
HFD1_k127_1656847_3 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002162 252.0
HFD1_k127_1656847_4 PFAM cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000324 239.0
HFD1_k127_1656847_5 heat shock protein K04762 - - 0.0000000000000000000000000000000000004254 143.0
HFD1_k127_1658339_0 Zn-dependent hydrolases including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 429.0
HFD1_k127_1658339_1 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000001609 200.0
HFD1_k127_1658339_2 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000003021 173.0
HFD1_k127_1661900_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 9.558e-239 757.0
HFD1_k127_1661900_1 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000004954 175.0
HFD1_k127_1664484_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 5.987e-263 823.0
HFD1_k127_1664484_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 471.0
HFD1_k127_1664484_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000006927 270.0
HFD1_k127_1664484_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000195 236.0
HFD1_k127_1664484_4 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000001414 132.0
HFD1_k127_1668892_0 Putative modulator of DNA gyrase K03568 - - 1.764e-228 716.0
HFD1_k127_1668892_1 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 604.0
HFD1_k127_1668892_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 357.0
HFD1_k127_1671162_0 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 604.0
HFD1_k127_1671162_1 PFAM Uracil-DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 295.0
HFD1_k127_1671162_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002068 240.0
HFD1_k127_1671162_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000001806 147.0
HFD1_k127_1676224_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 376.0
HFD1_k127_1676224_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000007157 77.0
HFD1_k127_1687143_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 5.738e-291 903.0
HFD1_k127_1687143_1 Catalyzes the transfer of electrons from NADH to quinone K00342 - 1.6.5.3 4.66e-242 766.0
HFD1_k127_1687143_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 568.0
HFD1_k127_1687143_3 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 418.0
HFD1_k127_1687143_4 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000011 224.0
HFD1_k127_1687143_5 - - - - 0.0000000000000000001318 100.0
HFD1_k127_1690939_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 598.0
HFD1_k127_1690939_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000007786 261.0
HFD1_k127_1690939_2 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000000000001623 102.0
HFD1_k127_1690939_3 lactoylglutathione lyase activity - - - 0.000000000000000000009014 108.0
HFD1_k127_1690939_4 Immunoglobulin - - - 0.000000000000004282 81.0
HFD1_k127_1690939_5 Belongs to the peptidase S8 family K14645 - - 0.00003948 52.0
HFD1_k127_1690975_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 524.0
HFD1_k127_1690975_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 349.0
HFD1_k127_1695101_0 Trap dicarboxylate transporter, dctm subunit - - - 3.972e-221 697.0
HFD1_k127_1695101_1 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 556.0
HFD1_k127_1695101_2 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000002391 233.0
HFD1_k127_1695101_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000004609 66.0
HFD1_k127_1695101_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0003881 44.0
HFD1_k127_171052_0 COG3267 Type II secretory pathway, component ExeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 371.0
HFD1_k127_171052_1 COG0489 ATPases involved in chromosome partitioning K08252 - 2.7.10.1 0.00000000000000000000000000000000332 130.0
HFD1_k127_171052_2 polysaccharide deactylase family protein - - - 0.000000000000000000000000000001792 124.0
HFD1_k127_1711874_0 RND efflux system, outer membrane K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 325.0
HFD1_k127_1711874_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001238 229.0
HFD1_k127_1711874_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000001303 151.0
HFD1_k127_1711874_3 COG0841 Cation multidrug efflux pump K03296,K18138 - - 0.000000000000000000000000000000009568 130.0
HFD1_k127_1713278_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 426.0
HFD1_k127_1713278_1 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 336.0
HFD1_k127_1713278_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000893 250.0
HFD1_k127_1713278_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000002454 156.0
HFD1_k127_1713278_4 Protein of unknown function (DUF4019) - - - 0.00000000000000000002211 96.0
HFD1_k127_1720628_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 429.0
HFD1_k127_1720628_1 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 340.0
HFD1_k127_1720628_2 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 333.0
HFD1_k127_1720628_3 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006977 255.0
HFD1_k127_1737365_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 328.0
HFD1_k127_1737365_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000003888 84.0
HFD1_k127_1743003_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1149.0
HFD1_k127_1743003_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 512.0
HFD1_k127_1743003_2 COG1538 Outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 326.0
HFD1_k127_1743003_3 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000000000004911 162.0
HFD1_k127_1743003_4 Copper binding periplasmic protein CusF - - - 0.0000000000000000004516 91.0
HFD1_k127_1743003_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000001343 87.0
HFD1_k127_1745210_0 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.000000000000000000000000000000000000000000000000003199 189.0
HFD1_k127_1745210_1 - - - - 0.000000000002234 74.0
HFD1_k127_1745210_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000002207 53.0
HFD1_k127_1746589_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 6.418e-228 719.0
HFD1_k127_1746589_1 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 370.0
HFD1_k127_1746589_2 ferredoxin - - - 0.0000000000000000000000000000000005674 131.0
HFD1_k127_1768539_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 574.0
HFD1_k127_1768539_1 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 314.0
HFD1_k127_1768539_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001185 202.0
HFD1_k127_1768539_3 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000364 187.0
HFD1_k127_1768539_4 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000006574 190.0
HFD1_k127_1768539_5 - - - - 0.0000000000000000000000000000003809 128.0
HFD1_k127_1768539_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000001456 65.0
HFD1_k127_1774971_0 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 4.849e-294 904.0
HFD1_k127_1774971_1 Transglycosylase SLT domain - - - 0.000000000000000000000000001044 113.0
HFD1_k127_1776932_0 RNB K01147 - 3.1.13.1 5.302e-226 728.0
HFD1_k127_1776932_1 MgtE intracellular N domain K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 599.0
HFD1_k127_1776932_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 353.0
HFD1_k127_1776932_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 299.0
HFD1_k127_1776932_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 289.0
HFD1_k127_1776932_5 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000002068 237.0
HFD1_k127_1776932_6 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000002524 213.0
HFD1_k127_1776932_7 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000001629 211.0
HFD1_k127_1776932_8 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000000001081 214.0
HFD1_k127_1776932_9 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000000000007217 164.0
HFD1_k127_1780440_0 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 374.0
HFD1_k127_1780440_1 Domain of unknown function (DUF4410) - - - 0.00002136 52.0
HFD1_k127_1784354_0 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001637 276.0
HFD1_k127_1784354_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000002649 176.0
HFD1_k127_1784354_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000001107 180.0
HFD1_k127_1794295_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.93e-315 974.0
HFD1_k127_1794295_1 Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000000000000000002963 222.0
HFD1_k127_1794295_2 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000005397 170.0
HFD1_k127_1811668_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 313.0
HFD1_k127_1811668_1 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000293 271.0
HFD1_k127_1811668_2 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000000000000000000000000000000000006024 242.0
HFD1_k127_1825983_0 arylsulfatase A K01130 - 3.1.6.1 4.89e-284 876.0
HFD1_k127_1825983_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000322 224.0
HFD1_k127_1825983_2 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000005242 179.0
HFD1_k127_182707_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 576.0
HFD1_k127_182707_1 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 419.0
HFD1_k127_182707_2 belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 390.0
HFD1_k127_1838367_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 311.0
HFD1_k127_1838367_1 ABC-2 family transporter protein K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 302.0
HFD1_k127_1838367_2 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007022 275.0
HFD1_k127_1838367_3 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002886 233.0
HFD1_k127_1838367_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000006528 166.0
HFD1_k127_1846452_0 PFAM transposase mutator type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 590.0
HFD1_k127_1846452_1 Transposase DDE domain - - - 0.00000000000000000000000005362 110.0
HFD1_k127_184844_0 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 357.0
HFD1_k127_184844_1 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 349.0
HFD1_k127_184844_2 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.0000000000000000000001127 97.0
HFD1_k127_1853890_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 469.0
HFD1_k127_1853890_1 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 349.0
HFD1_k127_1853890_2 lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000004405 236.0
HFD1_k127_1853890_3 TIGRFAM Cu(I)-responsive transcriptional regulator K19591 - - 0.0000000000000000000000000000000000000000000000568 172.0
HFD1_k127_1853890_4 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.0000000000000000000000000000000000001575 144.0
HFD1_k127_1853890_5 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000003454 141.0
HFD1_k127_1853890_6 FabA-like domain - - - 0.00000000000000000000000000004134 128.0
HFD1_k127_1853890_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000001734 63.0
HFD1_k127_1867700_0 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 357.0
HFD1_k127_1867700_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003734 281.0
HFD1_k127_1867700_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003035 267.0
HFD1_k127_1867700_3 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000008395 151.0
HFD1_k127_1867700_4 Glutathione peroxidase - - - 0.00000000000000003095 84.0
HFD1_k127_1867853_0 Magnesium transport protein CorA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 344.0
HFD1_k127_1867853_1 Esterase PHB depolymerase - - - 0.00000000000000009257 79.0
HFD1_k127_188010_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 386.0
HFD1_k127_188010_1 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 329.0
HFD1_k127_1880928_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 613.0
HFD1_k127_190577_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.222e-224 707.0
HFD1_k127_190577_1 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005275 299.0
HFD1_k127_190577_2 Domain of unknown function (DUF4382) - - - 0.00000009556 58.0
HFD1_k127_1915359_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 358.0
HFD1_k127_1915359_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 301.0
HFD1_k127_1915359_2 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000001662 232.0
HFD1_k127_193974_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 564.0
HFD1_k127_193974_1 Belongs to the DapB family K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 343.0
HFD1_k127_193974_2 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007284 239.0
HFD1_k127_193974_3 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000002346 231.0
HFD1_k127_193974_4 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000001203 115.0
HFD1_k127_193974_5 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.000000000000000000000000005344 113.0
HFD1_k127_193974_6 acyl-CoA dehydrogenase - - - 0.0000000000001888 69.0
HFD1_k127_1941804_0 Dynamin family - - - 1.132e-195 639.0
HFD1_k127_1941804_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 428.0
HFD1_k127_1941804_10 Phosphate starvation-inducible protein, PSIF - - - 0.000000000000000000003634 97.0
HFD1_k127_1941804_2 a g-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 377.0
HFD1_k127_1941804_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 342.0
HFD1_k127_1941804_4 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 344.0
HFD1_k127_1941804_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000005101 244.0
HFD1_k127_1941804_6 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000001121 201.0
HFD1_k127_1941804_7 PFAM peptidase S16 lon domain protein K07157 - - 0.000000000000000000000000000000000000000000001296 183.0
HFD1_k127_1941804_8 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000012 104.0
HFD1_k127_1941804_9 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000000000001272 108.0
HFD1_k127_194870_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 442.0
HFD1_k127_194870_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 329.0
HFD1_k127_194870_2 heptosyltransferase K02843 - - 0.000000000000000000000000000000000000000000000000000002822 206.0
HFD1_k127_194870_3 Glycosyltransferase family 25 (LPS biosynthesis protein) K07270 - - 0.00000000000000000000000000000000000000000000000000003215 211.0
HFD1_k127_194870_4 PFAM O-Antigen - - - 0.0000000000000000000000000000000000007065 160.0
HFD1_k127_194870_5 N-terminal domain of galactosyltransferase - - - 0.000000000000001497 77.0
HFD1_k127_1955089_0 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002822 282.0
HFD1_k127_1955089_1 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000003137 228.0
HFD1_k127_1955089_2 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000000000000000000000000000000000000002732 192.0
HFD1_k127_1955089_3 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 0.000000000000000000000000000000000000001232 159.0
HFD1_k127_1971391_0 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 386.0
HFD1_k127_198100_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 546.0
HFD1_k127_198100_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 391.0
HFD1_k127_198100_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000292 275.0
HFD1_k127_198100_3 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000009903 86.0
HFD1_k127_1986615_0 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001185 278.0
HFD1_k127_1986615_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000009402 114.0
HFD1_k127_1986615_2 alginate biosynthesis protein AlgZ FimS K08082 - 2.7.13.3 0.0000001065 54.0
HFD1_k127_1987947_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001906 259.0
HFD1_k127_1987947_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000005889 257.0
HFD1_k127_1987947_2 Type II transport protein GspH K08084 - - 0.00000000000113 76.0
HFD1_k127_1987947_3 type IV pilus modification protein PilV K02671 - - 0.00001996 51.0
HFD1_k127_2044360_0 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 359.0
HFD1_k127_2044360_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005174 289.0
HFD1_k127_2044360_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000004612 213.0
HFD1_k127_2044360_3 Drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000008625 208.0
HFD1_k127_2044360_4 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000000338 216.0
HFD1_k127_2044360_5 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.0000000000000000000000000000000000000000004296 165.0
HFD1_k127_2044360_6 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000001425 108.0
HFD1_k127_2044360_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000002378 55.0
HFD1_k127_2055318_0 Aminotransferase K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 500.0
HFD1_k127_2055318_1 PFAM peptidase M14, carboxypeptidase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 289.0
HFD1_k127_2055318_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000001734 115.0
HFD1_k127_2068849_0 PFAM amidohydrolase K01464 - 3.5.2.2 3.682e-204 642.0
HFD1_k127_2068849_1 FCD - - - 0.0000000008987 62.0
HFD1_k127_2088810_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 395.0
HFD1_k127_2088810_1 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 382.0
HFD1_k127_2088810_2 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 319.0
HFD1_k127_210427_0 helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 438.0
HFD1_k127_210427_1 - - - - 0.0000000000000000000000000000000000003043 152.0
HFD1_k127_210714_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 557.0
HFD1_k127_2123427_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000001478 243.0
HFD1_k127_2123427_1 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.00000000000000000000000000000000000000009642 157.0
HFD1_k127_2148491_0 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 479.0
HFD1_k127_2148491_1 abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004337 240.0
HFD1_k127_2148491_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.00000000000000000000000000000000000000000000000003863 180.0
HFD1_k127_2148491_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000003861 70.0
HFD1_k127_2149748_0 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 610.0
HFD1_k127_2149748_1 cytochrome K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 354.0
HFD1_k127_2149748_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000004856 145.0
HFD1_k127_2149748_3 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000007927 125.0
HFD1_k127_2168925_0 - - - - 0.0000000000000000000000000000000000000000000000895 182.0
HFD1_k127_2168925_1 beta-lactamase - - - 0.0000000000000000000004761 106.0
HFD1_k127_2168925_2 Protein of unknown function (DUF1289) K06938 - - 0.000000000000000001362 88.0
HFD1_k127_2168925_3 - - - - 0.0000000005288 68.0
HFD1_k127_221235_0 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.549e-287 895.0
HFD1_k127_221235_1 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 5.481e-204 647.0
HFD1_k127_221235_2 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 497.0
HFD1_k127_221235_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 433.0
HFD1_k127_221235_4 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 430.0
HFD1_k127_221235_5 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 377.0
HFD1_k127_221235_6 Cyclic nucleotide-binding - - - 0.000001335 53.0
HFD1_k127_221348_0 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000184 259.0
HFD1_k127_2225419_0 Amidase K02433 - 6.3.5.6,6.3.5.7 3.044e-227 715.0
HFD1_k127_2225419_1 Receptor family ligand binding region - - - 5.728e-224 698.0
HFD1_k127_2225419_10 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000006355 164.0
HFD1_k127_2225419_11 Protein of unknown function, DUF488 - - - 0.0000000000000000000000001293 111.0
HFD1_k127_2225419_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 530.0
HFD1_k127_2225419_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 522.0
HFD1_k127_2225419_4 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 434.0
HFD1_k127_2225419_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 418.0
HFD1_k127_2225419_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 345.0
HFD1_k127_2225419_7 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 306.0
HFD1_k127_2225419_8 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000404 247.0
HFD1_k127_2225419_9 Ureidoglycolate lyase K01483 - 4.3.2.3 0.000000000000000000000000000000000000000000000000000001205 199.0
HFD1_k127_2227372_0 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 611.0
HFD1_k127_2231303_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 349.0
HFD1_k127_2231303_1 Belongs to the peptidase S1C family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 310.0
HFD1_k127_2231303_2 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000004445 160.0
HFD1_k127_2249521_0 Secretin and TonB N terminus short domain K02666 - - 2.041e-233 746.0
HFD1_k127_2249521_1 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004979 260.0
HFD1_k127_2249521_2 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000000005218 203.0
HFD1_k127_2249521_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000001407 186.0
HFD1_k127_2249521_4 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000000000001959 185.0
HFD1_k127_2249521_5 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000352 160.0
HFD1_k127_2308084_0 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 316.0
HFD1_k127_2308084_1 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.0000000000000000000000000000000000000000000000000000000002725 203.0
HFD1_k127_2308084_2 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000005188 194.0
HFD1_k127_2308084_3 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.000000000000000000004535 93.0
HFD1_k127_233348_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 7.191e-255 796.0
HFD1_k127_233348_1 Na Pi-cotransporter II-related protein K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 558.0
HFD1_k127_233348_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.0000000000000000000000000000000000000000000000000000000000000009383 221.0
HFD1_k127_233484_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000001257 71.0
HFD1_k127_2341183_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 438.0
HFD1_k127_2341183_1 von Willebrand factor type A domain K07114 - - 0.000000000000000002051 98.0
HFD1_k127_2411479_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 522.0
HFD1_k127_2411479_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 505.0
HFD1_k127_2411479_2 Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 472.0
HFD1_k127_2411479_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 438.0
HFD1_k127_2411479_4 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 384.0
HFD1_k127_2411479_5 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000004863 197.0
HFD1_k127_2411479_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000001524 175.0
HFD1_k127_2411479_7 Endonuclease Exonuclease Phosphatase - - - 0.0000000000414 73.0
HFD1_k127_2417215_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 440.0
HFD1_k127_2417215_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 289.0
HFD1_k127_2417215_2 cell division K09812 - - 0.00000000000000000000000000000000000000000000000000000001901 205.0
HFD1_k127_2417215_3 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000002196 193.0
HFD1_k127_2417215_4 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000001114 102.0
HFD1_k127_2436605_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 430.0
HFD1_k127_2436605_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 380.0
HFD1_k127_2436605_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 355.0
HFD1_k127_2436605_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 328.0
HFD1_k127_2436605_4 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 319.0
HFD1_k127_2436605_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 300.0
HFD1_k127_2436605_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000007657 118.0
HFD1_k127_2447565_0 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 566.0
HFD1_k127_2447565_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 391.0
HFD1_k127_2447565_2 Decaheme c-type cytochrome, DmsE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 327.0
HFD1_k127_2447565_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003383 277.0
HFD1_k127_2447565_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000008661 259.0
HFD1_k127_2447565_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000002255 68.0
HFD1_k127_2447565_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000006129 61.0
HFD1_k127_2449365_0 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 4.203e-214 672.0
HFD1_k127_2449365_1 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002716 277.0
HFD1_k127_2449365_2 Periplasmic or secreted lipoprotein - - - 0.00000000000000000005329 96.0
HFD1_k127_2459657_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 283.0
HFD1_k127_2459657_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000000562 212.0
HFD1_k127_2459657_2 Nudix hydrolase - - - 0.00000000000000000000000000000000000007043 149.0
HFD1_k127_2470478_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1346.0
HFD1_k127_2470478_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000188 252.0
HFD1_k127_2471631_0 Sodium:solute symporter family K14392 - - 1.987e-194 617.0
HFD1_k127_2471631_1 - - - - 0.00000000000000000000000000000000002624 147.0
HFD1_k127_2473157_0 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 451.0
HFD1_k127_2473157_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 451.0
HFD1_k127_2481959_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.926e-299 937.0
HFD1_k127_2481959_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 548.0
HFD1_k127_2481959_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000008807 188.0
HFD1_k127_2481959_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000001677 110.0
HFD1_k127_2482132_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 4.579e-237 739.0
HFD1_k127_2482132_1 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000005573 253.0
HFD1_k127_2482132_2 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000001111 233.0
HFD1_k127_2482132_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000209 145.0
HFD1_k127_2482132_4 Putative regulatory protein - - - 0.0000000000000000000000000009515 118.0
HFD1_k127_2488455_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 5.036e-211 664.0
HFD1_k127_2488455_1 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 429.0
HFD1_k127_2488455_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 308.0
HFD1_k127_249012_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 325.0
HFD1_k127_249012_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000009049 126.0
HFD1_k127_249012_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000004094 123.0
HFD1_k127_249012_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000589 96.0
HFD1_k127_2493216_0 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 434.0
HFD1_k127_2493216_1 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000009722 98.0
HFD1_k127_2493216_2 membrane - - - 0.0000000000003188 78.0
HFD1_k127_2493216_3 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.000000006668 57.0
HFD1_k127_2496455_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.103e-215 674.0
HFD1_k127_2496455_1 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 339.0
HFD1_k127_2496455_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 291.0
HFD1_k127_2496455_3 acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005844 282.0
HFD1_k127_2496646_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 8.353e-230 728.0
HFD1_k127_2496646_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 362.0
HFD1_k127_2496646_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 344.0
HFD1_k127_2496646_3 transcriptional Regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 342.0
HFD1_k127_2496646_4 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001416 291.0
HFD1_k127_2496646_5 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000003816 223.0
HFD1_k127_2496646_6 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000000000000000102 181.0
HFD1_k127_2496646_7 - - - - 0.000000000000000000000000000002009 134.0
HFD1_k127_2496646_8 Antirepressor - - - 0.000005833 55.0
HFD1_k127_2496646_9 DNA alkylation repair - - - 0.00001016 52.0
HFD1_k127_2497537_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 6.494e-194 634.0
HFD1_k127_2497537_1 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000001241 240.0
HFD1_k127_2497537_2 Ami_3 K01448 - 3.5.1.28 0.0000000000000002158 79.0
HFD1_k127_2502992_0 Participates in both transcription termination and antitermination K02600 - - 1.406e-219 692.0
HFD1_k127_2502992_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 360.0
HFD1_k127_2502992_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001815 277.0
HFD1_k127_2502992_3 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000009879 203.0
HFD1_k127_2502992_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000002596 153.0
HFD1_k127_2502992_5 Thioesterase superfamily - - - 0.0000000000000000000000000000000000001507 144.0
HFD1_k127_2502992_6 Translation-initiation factor 2 K02519 - - 0.00000109 51.0
HFD1_k127_2505160_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 4.304e-314 969.0
HFD1_k127_2505160_1 RNA polymerase K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006657 275.0
HFD1_k127_2505160_2 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000005016 189.0
HFD1_k127_2505160_3 Protein of unknown function (DUF3106) - - - 0.000000000000000000008789 98.0
HFD1_k127_2505160_4 Protein of unknown function (DUF3619) - - - 0.000000000000000001175 96.0
HFD1_k127_2506933_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 337.0
HFD1_k127_2509239_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 448.0
HFD1_k127_2509239_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 342.0
HFD1_k127_2518683_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 471.0
HFD1_k127_2518683_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 257.0
HFD1_k127_2518683_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000003049 222.0
HFD1_k127_2518683_3 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000005147 203.0
HFD1_k127_2518683_4 Protein of unknown function (DUF3530) - - - 0.0000000000000000000000000000000000003646 153.0
HFD1_k127_2518683_5 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000001062 75.0
HFD1_k127_2524202_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 446.0
HFD1_k127_2524202_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 432.0
HFD1_k127_2524202_2 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 421.0
HFD1_k127_2524202_3 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000001544 115.0
HFD1_k127_2527372_0 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 450.0
HFD1_k127_2527372_1 d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 299.0
HFD1_k127_2527372_2 type IV pilus modification protein PilV - - - 0.000000000000000000000000000003058 129.0
HFD1_k127_2527372_3 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000002618 93.0
HFD1_k127_2527372_4 Tfp pilus assembly protein - - - 0.0000000000000003626 90.0
HFD1_k127_2527372_5 COG4966 Tfp pilus assembly protein PilW K02672 - - 0.00000000006706 70.0
HFD1_k127_2527387_0 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004601 284.0
HFD1_k127_2527387_1 Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000000000000008583 141.0
HFD1_k127_2527387_2 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000000004135 117.0
HFD1_k127_2529484_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 6.411e-249 775.0
HFD1_k127_2529484_1 surface antigen variable number repeat protein K07001 - - 6.358e-207 668.0
HFD1_k127_2529484_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 608.0
HFD1_k127_2529484_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 369.0
HFD1_k127_2529484_5 - - - - 0.00000000000000000001838 99.0
HFD1_k127_2530739_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 341.0
HFD1_k127_2530739_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 320.0
HFD1_k127_2530739_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000002011 151.0
HFD1_k127_2530739_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000002257 67.0
HFD1_k127_2542640_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 551.0
HFD1_k127_2542640_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 550.0
HFD1_k127_2542640_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 406.0
HFD1_k127_2542640_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 346.0
HFD1_k127_2542640_4 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 304.0
HFD1_k127_2542640_5 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.000000000000000000000000000000000000000000000000000000000001667 222.0
HFD1_k127_2542640_6 Belongs to the DnaA family K10763 - - 0.000000000000000000000000000000000000000000000000001358 191.0
HFD1_k127_2542640_7 protein conserved in bacteria K09922 - - 0.00000000000000000000000000000000000000000000000000659 191.0
HFD1_k127_2542640_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000005481 161.0
HFD1_k127_2545731_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000007698 257.0
HFD1_k127_2551644_0 Glutaredoxin-family domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 310.0
HFD1_k127_2551644_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 284.0
HFD1_k127_2551644_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000105 168.0
HFD1_k127_2551644_3 PFAM zinc finger, DksA TraR C4-type - - - 0.00000000000000005175 88.0
HFD1_k127_2554786_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.12e-214 675.0
HFD1_k127_2554786_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 415.0
HFD1_k127_2554786_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 405.0
HFD1_k127_2554786_3 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 387.0
HFD1_k127_2554786_4 - - - - 0.0000000001654 67.0
HFD1_k127_2556604_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.264e-260 806.0
HFD1_k127_2556604_1 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 362.0
HFD1_k127_2556604_2 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000002391 233.0
HFD1_k127_2556604_3 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.000686 44.0
HFD1_k127_2563141_0 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 2.896e-198 617.0
HFD1_k127_2563141_1 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 430.0
HFD1_k127_2563141_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 403.0
HFD1_k127_2563141_3 Nitrate reductase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 385.0
HFD1_k127_2564509_0 Glutamate-cysteine ligase family 2(GCS2) - - - 4.359e-202 645.0
HFD1_k127_2564509_1 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003386 250.0
HFD1_k127_2564509_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000000000000000000000000002535 221.0
HFD1_k127_2564509_3 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000009841 106.0
HFD1_k127_2564509_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000002504 81.0
HFD1_k127_2582277_0 nitric oxide reductase K04561 - 1.7.2.5 0.0 1104.0
HFD1_k127_2582277_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 342.0
HFD1_k127_2582277_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000007994 196.0
HFD1_k127_2582277_3 Transcriptional regulator K13771 - - 0.00000000000000000000000000000000000000000000000005379 183.0
HFD1_k127_2582277_4 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000367 127.0
HFD1_k127_2582277_5 Hsp20/alpha crystallin family - - - 0.000000000041 67.0
HFD1_k127_2601984_0 RNA-metabolising metallo-beta-lactamase K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 466.0
HFD1_k127_2601984_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001019 207.0
HFD1_k127_2601984_2 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.00000000000000000000000000000001627 130.0
HFD1_k127_2618898_0 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 492.0
HFD1_k127_2618898_1 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 399.0
HFD1_k127_2618898_2 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002259 242.0
HFD1_k127_2618898_3 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000000000000000004364 201.0
HFD1_k127_262007_0 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 403.0
HFD1_k127_262007_1 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001215 282.0
HFD1_k127_262007_2 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000000001759 160.0
HFD1_k127_262007_3 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000000005169 164.0
HFD1_k127_262007_4 Thioredoxin-like - - - 0.000000000000000000000000000000000000001259 153.0
HFD1_k127_262007_5 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000002195 132.0
HFD1_k127_262007_6 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000005997 70.0
HFD1_k127_2630094_0 PFAM AMP-dependent synthetase and ligase - - - 9.179e-194 616.0
HFD1_k127_2630094_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000003662 60.0
HFD1_k127_2643861_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 591.0
HFD1_k127_2643861_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 477.0
HFD1_k127_2643861_2 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 355.0
HFD1_k127_2643861_3 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001764 257.0
HFD1_k127_2643861_4 Hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000001582 220.0
HFD1_k127_2643861_5 tail specific protease K03797 - 3.4.21.102 0.00000000003757 67.0
HFD1_k127_26485_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0 1106.0
HFD1_k127_26485_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000008603 209.0
HFD1_k127_26485_2 Phage integrase family - - - 0.000000000008638 70.0
HFD1_k127_26485_3 Benzoate membrane transport protein K05782 - - 0.000000000442 61.0
HFD1_k127_2649962_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.442e-206 654.0
HFD1_k127_2649962_1 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 462.0
HFD1_k127_2649962_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000006991 119.0
HFD1_k127_2655694_0 mitochondrial gene expression - - - 4.022e-255 824.0
HFD1_k127_2655694_1 ATPase involved in DNA repair K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 478.0
HFD1_k127_2655694_2 Zn-ribbon protein possibly nucleic acid-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000187 261.0
HFD1_k127_265653_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000001122 160.0
HFD1_k127_2661129_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 465.0
HFD1_k127_2661129_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 441.0
HFD1_k127_2661129_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 375.0
HFD1_k127_2661129_3 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 332.0
HFD1_k127_2661129_4 PFAM conserved K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001028 281.0
HFD1_k127_2681608_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 477.0
HFD1_k127_2681608_1 PFAM glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 426.0
HFD1_k127_2681608_2 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 426.0
HFD1_k127_2681608_3 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000001331 211.0
HFD1_k127_2681608_4 - - - - 0.00000000000000000000000000000000000000001516 156.0
HFD1_k127_2705549_0 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 492.0
HFD1_k127_2705549_1 Chromate resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007832 244.0
HFD1_k127_2705549_2 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000001734 167.0
HFD1_k127_2705549_3 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000006799 101.0
HFD1_k127_2705549_4 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000001004 101.0
HFD1_k127_2732020_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 2.51e-321 996.0
HFD1_k127_2732020_1 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 522.0
HFD1_k127_2732020_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 495.0
HFD1_k127_2732020_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 353.0
HFD1_k127_2732020_4 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 333.0
HFD1_k127_2732020_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 300.0
HFD1_k127_2732020_6 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008136 265.0
HFD1_k127_2732020_7 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000248 118.0
HFD1_k127_2732020_8 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0004827 43.0
HFD1_k127_2732832_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 460.0
HFD1_k127_2732832_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 315.0
HFD1_k127_2735472_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 327.0
HFD1_k127_2735472_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 326.0
HFD1_k127_2735472_2 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000007391 163.0
HFD1_k127_2736656_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 494.0
HFD1_k127_2736656_1 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 467.0
HFD1_k127_2736656_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 405.0
HFD1_k127_2755664_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.495e-251 781.0
HFD1_k127_2755664_1 AMP-binding enzyme C-terminal domain K18661 - - 2.411e-221 698.0
HFD1_k127_2755664_2 PFAM Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 497.0
HFD1_k127_2755664_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 348.0
HFD1_k127_2755664_4 GrpB protein - - - 0.0000000000000000000000000000000000004704 150.0
HFD1_k127_2782429_0 Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5- (5- phosphoribosylamino)methylideneamino imidazole-4-carboxamide K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 393.0
HFD1_k127_2782429_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 290.0
HFD1_k127_2782429_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006617 273.0
HFD1_k127_2782429_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000001086 261.0
HFD1_k127_2786603_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 300.0
HFD1_k127_2801076_0 ABC-type Fe3 transport system, permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 527.0
HFD1_k127_2801076_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 419.0
HFD1_k127_2801076_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 359.0
HFD1_k127_2801076_3 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 328.0
HFD1_k127_2801076_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055 330.0
HFD1_k127_2801076_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000008382 128.0
HFD1_k127_2838758_0 general secretion pathway protein D K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 412.0
HFD1_k127_2838758_1 General Secretory Pathway K02463 - - 0.0000000000000000000000000000000000000000001056 169.0
HFD1_k127_2838758_2 involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000002688 104.0
HFD1_k127_2838758_3 General secretion pathway K02462 - - 0.0000000000000000008096 94.0
HFD1_k127_2847916_0 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 361.0
HFD1_k127_2847916_1 ABC transporter C-terminal domain K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003213 272.0
HFD1_k127_2847916_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000001859 100.0
HFD1_k127_285128_0 4-hydroxyphenylacetate K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 526.0
HFD1_k127_285128_1 Dehydrogenase K00101 - 1.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 336.0
HFD1_k127_2865217_0 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 395.0
HFD1_k127_2865217_1 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000193 216.0
HFD1_k127_296243_0 Mo-co oxidoreductase dimerisation domain K17225 - - 2.251e-214 672.0
HFD1_k127_296243_1 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000184 250.0
HFD1_k127_296243_2 - - - - 0.000737 48.0
HFD1_k127_299618_0 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 305.0
HFD1_k127_299618_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000004932 238.0
HFD1_k127_299618_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000128 156.0
HFD1_k127_299618_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000005692 105.0
HFD1_k127_3005888_0 PFAM nitrite and sulphite reductase 4Fe-4S K00381 - 1.8.1.2 1.081e-238 750.0
HFD1_k127_3005888_1 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 509.0
HFD1_k127_3005888_10 protein conserved in bacteria - - - 0.000000000000000000000000006663 118.0
HFD1_k127_3005888_2 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 494.0
HFD1_k127_3005888_3 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 454.0
HFD1_k127_3005888_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 454.0
HFD1_k127_3005888_5 TIGRFAM sulfate ABC transporter, permease protein CysW, sulfate ABC transporter, permease protein K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 433.0
HFD1_k127_3005888_6 sulfate ABC transporter, inner membrane subunit CysT K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 371.0
HFD1_k127_3005888_7 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 344.0
HFD1_k127_3005888_8 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 308.0
HFD1_k127_3005888_9 EAL domain protein - - - 0.00000000000000000000000000000006095 137.0
HFD1_k127_304080_0 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 279.0
HFD1_k127_304080_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001689 262.0
HFD1_k127_3088767_0 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 343.0
HFD1_k127_3088767_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000001395 143.0
HFD1_k127_3088767_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000009699 113.0
HFD1_k127_3088767_3 - - - - 0.00001262 49.0
HFD1_k127_3112914_0 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 414.0
HFD1_k127_3112914_1 Protein of unknown function (DUF2891) - - - 0.0000005826 51.0
HFD1_k127_3147137_0 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 493.0
HFD1_k127_3147137_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 425.0
HFD1_k127_3159712_0 pathogenesis - - - 0.0000000000000000000000000000000000000000000000000001036 199.0
HFD1_k127_3159712_1 - - - - 0.000000000000000000000000000000000000001647 151.0
HFD1_k127_3159712_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000007777 120.0
HFD1_k127_3159712_3 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.000000000004607 66.0
HFD1_k127_3195880_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 604.0
HFD1_k127_3195880_1 protein conserved in bacteria K09800 - - 0.000000000000000000007593 96.0
HFD1_k127_3218641_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 574.0
HFD1_k127_3218641_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009537 269.0
HFD1_k127_3218641_2 ATPase (AAA K06923 - - 0.0000000000000000000004411 102.0
HFD1_k127_3219068_0 Molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 516.0
HFD1_k127_3219068_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 281.0
HFD1_k127_3219068_3 Thioredoxin-like domain - - - 0.0000001034 55.0
HFD1_k127_3219265_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 4.341e-212 664.0
HFD1_k127_3219265_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 557.0
HFD1_k127_3219265_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 548.0
HFD1_k127_3219265_3 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 338.0
HFD1_k127_3219265_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 326.0
HFD1_k127_3219265_5 PFAM MucB RseB family protein K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000001709 243.0
HFD1_k127_3219265_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000009673 137.0
HFD1_k127_3219265_7 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000000000003351 92.0
HFD1_k127_3224618_0 PFAM Pentapeptide repeats (8 copies) - - - 0.000004458 57.0
HFD1_k127_3225426_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.817e-294 909.0
HFD1_k127_3225426_1 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 563.0
HFD1_k127_3226482_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002405 298.0
HFD1_k127_3226482_1 response to oxidative stress K04063 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000007405 201.0
HFD1_k127_3226482_2 DinB family - - - 0.000000000000000000000000000000000000000000000000000001926 196.0
HFD1_k127_3226482_3 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000001034 183.0
HFD1_k127_3226482_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000565 182.0
HFD1_k127_3226482_5 Subtilase family - - - 0.0000000000009377 68.0
HFD1_k127_3233849_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 359.0
HFD1_k127_3233849_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 298.0
HFD1_k127_3233849_2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000001183 210.0
HFD1_k127_3233849_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000001193 134.0
HFD1_k127_3233849_4 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000001297 134.0
HFD1_k127_3237944_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 432.0
HFD1_k127_3237944_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000003526 207.0
HFD1_k127_3239294_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 527.0
HFD1_k127_3239294_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 368.0
HFD1_k127_3249991_0 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 2.785e-208 662.0
HFD1_k127_3256868_0 Domain related to MnhB subunit of Na+/H+ antiporter K00341,K05559 - 1.6.5.3 2e-323 1020.0
HFD1_k127_3256868_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.952e-209 658.0
HFD1_k127_3256868_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 297.0
HFD1_k127_3256868_11 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000000000000001078 245.0
HFD1_k127_3256868_12 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000009079 234.0
HFD1_k127_3256868_13 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000002595 228.0
HFD1_k127_3256868_14 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000002236 193.0
HFD1_k127_3256868_15 Na+/H+ ion antiporter subunit - - - 0.0000000000000000000000000000000000000000000000002649 199.0
HFD1_k127_3256868_16 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000003232 145.0
HFD1_k127_3256868_17 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.00000000000000000000000000000000009178 152.0
HFD1_k127_3256868_18 Protein of unknown function (DUF3299) K09950 - - 0.0000000000000000000000000000000007151 136.0
HFD1_k127_3256868_19 COG1320 Multisubunit Na H antiporter, MnhG subunit K05564 - - 0.000000000000000000000000000006718 126.0
HFD1_k127_3256868_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 526.0
HFD1_k127_3256868_20 PFAM multiple resistance and pH regulation protein F K05563 - - 0.00000000000000000000000001893 111.0
HFD1_k127_3256868_21 Heavy-metal-associated domain - - - 0.0000000000003049 72.0
HFD1_k127_3256868_3 Cobalamin biosynthesis protein CobW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 511.0
HFD1_k127_3256868_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 441.0
HFD1_k127_3256868_5 Sodium calcium K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 421.0
HFD1_k127_3256868_6 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 433.0
HFD1_k127_3256868_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 391.0
HFD1_k127_3256868_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 370.0
HFD1_k127_3256868_9 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 332.0
HFD1_k127_3257535_0 Adenylate K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 643.0
HFD1_k127_3257535_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000001071 197.0
HFD1_k127_3257535_2 Alternative locus ID K03321 - - 0.000001734 56.0
HFD1_k127_3262287_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1094.0
HFD1_k127_3262287_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 570.0
HFD1_k127_3262287_2 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000001284 122.0
HFD1_k127_3263638_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 1.283e-319 986.0
HFD1_k127_3263638_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001615 243.0
HFD1_k127_3268298_0 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 318.0
HFD1_k127_3268298_1 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003881 246.0
HFD1_k127_3268298_2 - - - - 0.000000000000000000000000000000000000000000004893 171.0
HFD1_k127_3268298_3 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000001165 61.0
HFD1_k127_3268298_4 Nitrous oxide-stimulated promoter - - - 0.0000000001439 63.0
HFD1_k127_3269525_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.465e-231 728.0
HFD1_k127_3269525_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 400.0
HFD1_k127_3269525_2 transcriptional Regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 333.0
HFD1_k127_3269525_3 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000001824 150.0
HFD1_k127_3271503_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 435.0
HFD1_k127_3272734_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000002659 136.0
HFD1_k127_3275989_0 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 325.0
HFD1_k127_3275989_1 EamA-like transporter family - - - 0.0000000000000000000000000000000001001 136.0
HFD1_k127_327741_0 OmpA family - - - 4.608e-266 826.0
HFD1_k127_3282373_0 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 497.0
HFD1_k127_3282373_1 C-terminal, D2-small domain, of ClpB protein K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 345.0
HFD1_k127_3282373_2 Phosphoglycerate mutase - - - 0.00000006417 56.0
HFD1_k127_3283411_0 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 367.0
HFD1_k127_3283411_1 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005868 271.0
HFD1_k127_3283411_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000002085 59.0
HFD1_k127_330024_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.636e-259 803.0
HFD1_k127_3302816_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 548.0
HFD1_k127_3302816_1 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 505.0
HFD1_k127_3302816_10 DUF218 domain - - - 0.000000000000000000000000000000000000000000007449 171.0
HFD1_k127_3302816_2 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 422.0
HFD1_k127_3302816_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 416.0
HFD1_k127_3302816_4 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 370.0
HFD1_k127_3302816_5 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001356 298.0
HFD1_k127_3302816_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001303 248.0
HFD1_k127_3302816_7 lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000001445 215.0
HFD1_k127_3302816_8 Haem-degrading K11477 - - 0.00000000000000000000000000000000000000000000000000007684 194.0
HFD1_k127_3302816_9 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000000003767 169.0
HFD1_k127_3335581_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 490.0
HFD1_k127_3335581_1 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 389.0
HFD1_k127_3335581_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 292.0
HFD1_k127_3335581_3 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001485 282.0
HFD1_k127_3335581_4 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000001884 161.0
HFD1_k127_3335581_5 PFAM DnaJ homologue, subfamily C, member 28 - - - 0.000000000000001832 80.0
HFD1_k127_333810_0 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 392.0
HFD1_k127_333810_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 329.0
HFD1_k127_333810_2 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000002592 160.0
HFD1_k127_333810_3 - - - - 0.0000000000000000000000000000003169 124.0
HFD1_k127_333810_4 - - - - 0.000000000000000000000000000001777 122.0
HFD1_k127_3340469_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 528.0
HFD1_k127_3340469_1 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 359.0
HFD1_k127_3340469_2 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 312.0
HFD1_k127_3340469_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001971 275.0
HFD1_k127_3340469_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000005413 272.0
HFD1_k127_3340469_5 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000001493 121.0
HFD1_k127_3345462_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 596.0
HFD1_k127_3345462_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 512.0
HFD1_k127_3345462_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 443.0
HFD1_k127_3345462_3 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 371.0
HFD1_k127_3345462_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000009657 238.0
HFD1_k127_3345462_5 Protein of unknown function (DUF2946) - - - 0.000000000000000000000000000000000000000005266 161.0
HFD1_k127_3345462_6 SnoaL-like domain - - - 0.000000000000000000000000000000000007626 144.0
HFD1_k127_3345462_7 Zinc-finger domain - - - 0.0000000000000000000006731 102.0
HFD1_k127_3345462_8 Major facilitator superfamily - - - 0.0000000007844 62.0
HFD1_k127_3345462_9 Ornithine cyclodeaminase K01750,K19742,K19743,K21721 - 1.5.1.1,1.5.1.49,1.5.1.51,4.3.1.12 0.0002762 46.0
HFD1_k127_3350083_0 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006042 278.0
HFD1_k127_3350083_1 Transcriptional regulator K05798 - - 0.00000000000000000000000000000000000000000000005699 181.0
HFD1_k127_3354641_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1181.0
HFD1_k127_3354641_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 315.0
HFD1_k127_3354641_2 permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 310.0
HFD1_k127_3354641_3 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000001202 144.0
HFD1_k127_3354641_4 Thioredoxin domain - - - 0.000000000000000000000000000003323 132.0
HFD1_k127_3354641_5 component of anaerobic dehydrogenases - - - 0.0000000000000000000000000003869 123.0
HFD1_k127_3354641_6 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000134 84.0
HFD1_k127_3357247_0 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 397.0
HFD1_k127_3357247_1 Transposase - - - 0.000000000000000000000000000000000000006345 147.0
HFD1_k127_3357247_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000001797 119.0
HFD1_k127_3357247_3 SnoaL-like polyketide cyclase - - - 0.0000003094 57.0
HFD1_k127_3360700_0 Peptidase M61 - - - 2.517e-221 704.0
HFD1_k127_3360700_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 458.0
HFD1_k127_3360700_2 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 422.0
HFD1_k127_3360700_3 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 328.0
HFD1_k127_3360700_4 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002208 269.0
HFD1_k127_3360700_5 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000000000000000000000000000000003137 204.0
HFD1_k127_3360700_6 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000005344 71.0
HFD1_k127_3360700_7 FAD-binding dehydrogenase K07077 - - 0.0003276 44.0
HFD1_k127_3367072_0 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 591.0
HFD1_k127_3367072_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000001218 108.0
HFD1_k127_3372255_0 Subtilase family - - - 2.66e-291 915.0
HFD1_k127_339179_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1299.0
HFD1_k127_339179_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 391.0
HFD1_k127_339179_2 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 325.0
HFD1_k127_339179_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000009234 249.0
HFD1_k127_3392675_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 9.445e-234 737.0
HFD1_k127_3392675_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 607.0
HFD1_k127_3392675_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 524.0
HFD1_k127_3392675_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 436.0
HFD1_k127_3392675_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000002987 108.0
HFD1_k127_3392675_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000005509 65.0
HFD1_k127_339726_0 Circularly permuted ATP-grasp type 2 - - - 7.352e-248 775.0
HFD1_k127_339726_1 Competence protein K02238 - - 1.232e-199 650.0
HFD1_k127_339726_2 PFAM Iron-containing alcohol dehydrogenase K19954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 546.0
HFD1_k127_339726_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 466.0
HFD1_k127_339726_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 375.0
HFD1_k127_339726_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000006496 89.0
HFD1_k127_3398241_0 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 459.0
HFD1_k127_3403685_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 419.0
HFD1_k127_3403685_1 NlpB/DapX lipoprotein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 366.0
HFD1_k127_3403685_2 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000001563 189.0
HFD1_k127_3403685_3 beta-lactamase - - - 0.0000000000000000000000000000000000009785 143.0
HFD1_k127_3407028_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1705.0
HFD1_k127_3407028_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000001283 226.0
HFD1_k127_3407028_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - - 0.000000000000000000000000000002291 121.0
HFD1_k127_3407028_3 RNA-binding protein K07574 - - 0.000000000000000000000000000008855 124.0
HFD1_k127_3425304_0 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 580.0
HFD1_k127_3425304_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 391.0
HFD1_k127_3425304_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 389.0
HFD1_k127_3425304_3 Molybdenum cofactor biosynthesis protein MogA K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 314.0
HFD1_k127_3425304_4 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 291.0
HFD1_k127_3425304_5 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000003339 155.0
HFD1_k127_3425304_6 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000000005809 152.0
HFD1_k127_3426142_0 RND efflux system, outer membrane lipoprotein K18139,K18903 - - 0.00000000000000000000000000000000000000000000004643 174.0
HFD1_k127_3426142_1 Protein conserved in bacteria K09924 - - 0.000000000000000000000000000000000000001128 153.0
HFD1_k127_3426142_2 KTSC domain - - - 0.0000000000000000003711 92.0
HFD1_k127_342910_0 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 434.0
HFD1_k127_342910_1 orn lys arg decarboxylase K01584 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 351.0
HFD1_k127_342910_2 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000002302 237.0
HFD1_k127_3433644_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 9.222e-240 748.0
HFD1_k127_3433644_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 3.375e-214 675.0
HFD1_k127_3433644_10 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000904 239.0
HFD1_k127_3433644_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000003854 198.0
HFD1_k127_3433644_12 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000001585 182.0
HFD1_k127_3433644_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000000003801 153.0
HFD1_k127_3433644_14 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000001138 85.0
HFD1_k127_3433644_2 Divergent 4Fe-4S mono-cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 508.0
HFD1_k127_3433644_3 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 445.0
HFD1_k127_3433644_4 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006279 284.0
HFD1_k127_3433644_5 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
HFD1_k127_3433644_6 Fatty acid desaturase K00496 - 1.14.15.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007727 278.0
HFD1_k127_3433644_7 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000001524 229.0
HFD1_k127_3433644_8 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000007855 218.0
HFD1_k127_3433644_9 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000000000000000000000002672 218.0
HFD1_k127_3434022_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 428.0
HFD1_k127_3434022_1 polysaccharide deactylase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 411.0
HFD1_k127_3456513_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000359 224.0
HFD1_k127_3456513_1 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000002477 213.0
HFD1_k127_3456513_2 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000000000000000000000148 196.0
HFD1_k127_3456513_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000004877 169.0
HFD1_k127_3456513_4 Rubredoxin - - - 0.000000000000000000000000000002383 120.0
HFD1_k127_3456513_5 CheW-like domain K02659 - - 0.0000000000000000000000000004657 125.0
HFD1_k127_345669_0 4Fe-4S dicluster domain K18930 - - 0.0 1113.0
HFD1_k127_345669_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000415 155.0
HFD1_k127_3466452_0 General secretion pathway protein L K02461 - - 0.0000000000000000000000000000000003143 147.0
HFD1_k127_3466452_1 General secretion pathway K02462 - - 0.000000000000000003815 92.0
HFD1_k127_3466452_2 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000002012 87.0
HFD1_k127_3481884_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 374.0
HFD1_k127_3481884_1 Belongs to the carbohydrate kinase PfkB family K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000001919 221.0
HFD1_k127_3481884_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000006087 137.0
HFD1_k127_3499189_0 Multicopper oxidase, type 3 - - - 7.391e-224 705.0
HFD1_k127_3499189_1 Multicopper oxidase - - - 8.268e-208 660.0
HFD1_k127_3499189_2 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
HFD1_k127_3499189_3 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000003002 161.0
HFD1_k127_3511375_0 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 1.819e-240 761.0
HFD1_k127_3511375_1 Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers K06955 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 - 0.0000000000000000000000000001321 120.0
HFD1_k127_3527882_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.42e-209 661.0
HFD1_k127_3527882_1 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 544.0
HFD1_k127_3527882_2 Tricorn protease C1 domain K03797 - 3.4.21.102 0.0000000000000000000000000000000000131 153.0
HFD1_k127_3527882_3 Sigma-70 region 2 - - - 0.000006316 59.0
HFD1_k127_3532338_0 Dehydrogenase K00382 - 1.8.1.4 1.563e-290 901.0
HFD1_k127_3532338_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 453.0
HFD1_k127_3532338_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 304.0
HFD1_k127_3532338_3 Proteasome subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004231 274.0
HFD1_k127_3532338_4 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000006087 194.0
HFD1_k127_3532338_5 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000000000006658 186.0
HFD1_k127_3532338_6 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000000002028 171.0
HFD1_k127_3532338_7 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000007257 83.0
HFD1_k127_3532338_8 Family of unknown function (DUF5329) - - - 0.00000000000001805 84.0
HFD1_k127_3533181_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.934e-259 815.0
HFD1_k127_3533181_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000143 251.0
HFD1_k127_3533181_2 Phospholipid methyltransferase - - - 0.000002294 56.0
HFD1_k127_3537875_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.264e-209 657.0
HFD1_k127_3537875_1 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008493 273.0
HFD1_k127_3537875_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000002 213.0
HFD1_k127_3537875_3 phenylacetic acid degradation protein K02614 - - 0.000000000000000000000000000000000000000000000000000005074 194.0
HFD1_k127_3539411_0 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 483.0
HFD1_k127_3539411_1 - - - - 0.00000000000000000000000000000000000000000653 162.0
HFD1_k127_3563182_0 aconitate hydratase K01681 - 4.2.1.3 1.879e-299 930.0
HFD1_k127_3563182_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 308.0
HFD1_k127_3563182_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003117 264.0
HFD1_k127_3563182_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000005711 194.0
HFD1_k127_3563182_4 protein conserved in bacteria K09966 - - 0.000000000000000000000000000000000000000000000000001284 185.0
HFD1_k127_3563182_5 MlaD protein K02067 - - 0.000000000000000000000000000000000000004604 165.0
HFD1_k127_3563182_6 PIN domain - - - 0.0000000000000000000000939 106.0
HFD1_k127_3563182_7 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000000003882 102.0
HFD1_k127_3566780_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.854e-262 811.0
HFD1_k127_3566780_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 326.0
HFD1_k127_3566780_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000008162 257.0
HFD1_k127_3567404_0 Cytochrome c554 and c-prime - - - 2.534e-221 722.0
HFD1_k127_3567404_1 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 473.0
HFD1_k127_3567404_2 ATPase MipZ K03496 - - 0.0000000000000002271 83.0
HFD1_k127_3570366_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 3309.0
HFD1_k127_3570366_1 methyltransferase - - - 0.000000001065 66.0
HFD1_k127_3578540_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1058.0
HFD1_k127_3578540_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.27e-258 815.0
HFD1_k127_3578540_2 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002425 281.0
HFD1_k127_3578540_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004508 259.0
HFD1_k127_3581370_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 8.816e-270 848.0
HFD1_k127_3581370_1 Cytochrome c oxidase caa3-type, assembly factor K02351 - - 0.00000000000000000000000000000000000000000000000000000000000001322 230.0
HFD1_k127_3581370_2 Cytochrome c oxidase subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000004359 238.0
HFD1_k127_3581370_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.000000000000000000000099 99.0
HFD1_k127_3581370_4 - - - - 0.00000000002493 75.0
HFD1_k127_3581370_5 - - - - 0.0002294 44.0
HFD1_k127_359164_0 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 485.0
HFD1_k127_359164_1 Belongs to the ClpA ClpB family K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 307.0
HFD1_k127_359164_2 Protein of unknown function (DUF3530) - - - 0.0000000000000000000000009893 107.0
HFD1_k127_359164_3 Cytochrome c, class I - - - 0.00000000000000000002953 96.0
HFD1_k127_3593068_0 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 382.0
HFD1_k127_3610568_0 Glycosyl hydrolases family 2, sugar binding domain K01190 - 3.2.1.23 0.0 1001.0
HFD1_k127_3610568_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002219 257.0
HFD1_k127_3628606_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 432.0
HFD1_k127_3628606_1 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 361.0
HFD1_k127_3628606_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000004858 139.0
HFD1_k127_3639259_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 473.0
HFD1_k127_3639259_1 COG3335 Transposase and inactivated derivatives - - - 0.000000000000000000000000004128 110.0
HFD1_k127_3639259_2 Protein of unknown function (DUF1499) - - - 0.000001696 50.0
HFD1_k127_3639585_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 402.0
HFD1_k127_3652078_0 Involved in initiation control of chromosome replication K07484 - - 8.108e-215 679.0
HFD1_k127_3652078_1 PFAM integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 419.0
HFD1_k127_3652078_2 recombinase activity K06400 - - 0.0001616 46.0
HFD1_k127_3658273_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 522.0
HFD1_k127_3658273_1 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 415.0
HFD1_k127_3658273_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000003016 170.0
HFD1_k127_3658273_3 - - - - 0.00000000000000000000000001492 114.0
HFD1_k127_3659127_0 PFAM transposase mutator type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 422.0
HFD1_k127_3659127_1 Transposase mutator type - - - 0.000000000000000000000000000000000000000000000008428 176.0
HFD1_k127_3659127_2 Transposase - - - 0.0000000000000000000000000000165 118.0
HFD1_k127_3674408_0 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 384.0
HFD1_k127_3678578_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000978 226.0
HFD1_k127_3678578_1 Lysine exporter protein (Lyse ygga) - - - 0.00000000000000000000000000000000000000000000000000000003601 206.0
HFD1_k127_3678578_2 Thioesterase superfamily - - - 0.00000000000000000000000004682 108.0
HFD1_k127_368632_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001641 263.0
HFD1_k127_368632_1 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000000000000532 101.0
HFD1_k127_3688998_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 543.0
HFD1_k127_3698795_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000002232 196.0
HFD1_k127_3698795_1 peptidase M48, Ste24p - - - 0.00000000000000000000000000000000000000000003389 173.0
HFD1_k127_3698795_2 Acetyltransferase (GNAT) domain K03825 - - 0.000000000000000000000000000000000000000002706 163.0
HFD1_k127_3698795_3 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000002371 155.0
HFD1_k127_3698795_4 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000001818 129.0
HFD1_k127_3704632_0 Belongs to the peptidase M16 family K07263 - - 6.559e-257 807.0
HFD1_k127_3704632_1 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000001254 153.0
HFD1_k127_3705359_0 ABC-type sugar transport system, periplasmic component K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 477.0
HFD1_k127_3705359_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 342.0
HFD1_k127_3705359_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000005626 264.0
HFD1_k127_3726392_0 Belongs to the transketolase family K00615 - 2.2.1.1 4.28e-298 927.0
HFD1_k127_3726392_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 614.0
HFD1_k127_3726392_2 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000008345 136.0
HFD1_k127_3748128_0 Transcriptional regulator K13635 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 432.0
HFD1_k127_3748128_1 Rhodanese-like domain - - - 0.0000000000000000000000000000000000001429 148.0
HFD1_k127_3748128_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000002022 112.0
HFD1_k127_3759602_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 541.0
HFD1_k127_3759602_1 LysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 464.0
HFD1_k127_3759602_2 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004607 246.0
HFD1_k127_3759602_3 Cupin 2, conserved barrel domain protein - - - 0.00000003655 62.0
HFD1_k127_3759602_4 LysR substrate binding domain K13635 - - 0.0000001009 53.0
HFD1_k127_3782205_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002656 275.0
HFD1_k127_3782205_1 AsmA family K07289 - - 0.000000000000000000000000000000000000001004 164.0
HFD1_k127_3782205_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000007283 113.0
HFD1_k127_3787802_0 Efflux pump K03296,K18138,K18322 - - 0.0 1043.0
HFD1_k127_3787802_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 406.0
HFD1_k127_3787802_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 338.0
HFD1_k127_3787802_3 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 284.0
HFD1_k127_3788758_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000005659 228.0
HFD1_k127_3788758_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000004404 177.0
HFD1_k127_3831218_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 348.0
HFD1_k127_3831218_1 Belongs to the 'phage' integrase family - - - 0.000001406 57.0
HFD1_k127_384174_0 Belongs to the 5'-nucleotidase family K01081,K17224 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 469.0
HFD1_k127_384174_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 428.0
HFD1_k127_384174_2 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000002107 210.0
HFD1_k127_384174_3 ATPase MipZ K03496 - - 0.0000000000000003726 79.0
HFD1_k127_3854629_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000001659 166.0
HFD1_k127_3854629_1 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000001989 85.0
HFD1_k127_3873228_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 288.0
HFD1_k127_3873228_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000001166 248.0
HFD1_k127_3873228_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000003103 200.0
HFD1_k127_3873228_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000001316 191.0
HFD1_k127_3873228_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000007681 173.0
HFD1_k127_3876969_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 389.0
HFD1_k127_3876969_1 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 366.0
HFD1_k127_3876969_2 Transglutaminase/protease-like homologues - - - 0.00000000000000000235 85.0
HFD1_k127_3895034_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1529.0
HFD1_k127_3895034_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 2.455e-210 661.0
HFD1_k127_3895034_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.45e-205 647.0
HFD1_k127_3895034_3 Sigma-54 interaction domain K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 545.0
HFD1_k127_3895034_4 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 352.0
HFD1_k127_3895034_5 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000753 257.0
HFD1_k127_3895034_6 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000002296 240.0
HFD1_k127_3895034_7 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000001233 242.0
HFD1_k127_3906988_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 8.965e-290 902.0
HFD1_k127_3909701_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000002097 151.0
HFD1_k127_391421_0 Plasmid pRiA4b ORF-3-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 304.0
HFD1_k127_391421_1 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 286.0
HFD1_k127_391421_2 Transposase - - - 0.000000000000000000000000000000008641 127.0
HFD1_k127_3947268_0 PFAM peptidase M14, carboxypeptidase A - - - 0.000000000000000000000000000000000000000000000000000000000000000006524 227.0
HFD1_k127_3947268_1 - - - - 0.00000000000000001105 84.0
HFD1_k127_3947268_2 3' exoribonuclease, RNase T-like - - - 0.000002194 60.0
HFD1_k127_3947268_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000361 56.0
HFD1_k127_3999860_0 4Fe-4S dicluster domain - - - 0.0 1124.0
HFD1_k127_3999860_1 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005399 259.0
HFD1_k127_4015331_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 349.0
HFD1_k127_4015331_1 Protein of unknown function (DUF3079) - - - 0.0000000000000000000000007016 105.0
HFD1_k127_4015331_2 Protein of unknown function (DUF962) - - - 0.00000000000000000000004888 98.0
HFD1_k127_4015331_3 Protein of unknown function (DUF861) K06995 - - 0.00000000000000000003725 99.0
HFD1_k127_4026681_0 DNA helicase K03657 - 3.6.4.12 2.017e-232 734.0
HFD1_k127_4026681_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004609 252.0
HFD1_k127_4029404_0 DNA helicase K03654 - 3.6.4.12 5.012e-225 728.0
HFD1_k127_4029404_1 Thioesterase superfamily - - - 0.0000000000000000000000000000000003697 134.0
HFD1_k127_4029404_2 membrane - - - 0.00000000000001623 88.0
HFD1_k127_4029404_3 helix_turn_helix, mercury resistance - - - 0.0000000003988 61.0
HFD1_k127_4033215_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 5.981e-217 675.0
HFD1_k127_4033215_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000645 162.0
HFD1_k127_4037835_0 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008764 268.0
HFD1_k127_4037835_1 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000004389 132.0
HFD1_k127_4037835_2 PFAM Transglycosylase-associated protein - - - 0.0000000000000000000000000001056 119.0
HFD1_k127_4037835_3 Glycine zipper 2TM domain K04062 - - 0.0000000000000000000758 90.0
HFD1_k127_4037835_4 carbohydrate binding - - - 0.0000000000000005129 80.0
HFD1_k127_4041351_0 THUMP domain K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 422.0
HFD1_k127_4041351_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000005418 247.0
HFD1_k127_4041351_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 233.0
HFD1_k127_4041351_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000009208 157.0
HFD1_k127_4041351_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000316 143.0
HFD1_k127_4044584_0 TonB-linked outer membrane protein, SusC RagA family - - - 4.034e-310 963.0
HFD1_k127_4044584_1 Starch-binding associating with outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 492.0
HFD1_k127_4056829_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 448.0
HFD1_k127_4056829_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 355.0
HFD1_k127_4056829_2 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001282 264.0
HFD1_k127_4056829_3 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000007296 181.0
HFD1_k127_4066390_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1030.0
HFD1_k127_4066390_1 - - - - 0.00000000001717 67.0
HFD1_k127_4069691_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.645e-217 693.0
HFD1_k127_4069691_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 384.0
HFD1_k127_4069691_10 general secretion pathway protein - - - 0.000002841 50.0
HFD1_k127_4069691_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002534 265.0
HFD1_k127_4069691_3 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000000000004638 220.0
HFD1_k127_4069691_4 import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000003157 211.0
HFD1_k127_4069691_5 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000001607 187.0
HFD1_k127_4069691_6 PFAM Secreted repeat of - - - 0.000000000000000000000000000000000000000000000000004387 184.0
HFD1_k127_4069691_7 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000006024 166.0
HFD1_k127_4069691_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000001213 149.0
HFD1_k127_4069691_9 SCP-2 sterol transfer family K03690 - - 0.000000000000000000000000000000005145 136.0
HFD1_k127_4071920_0 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 462.0
HFD1_k127_4071920_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 436.0
HFD1_k127_4071920_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 424.0
HFD1_k127_4071920_3 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000005376 160.0
HFD1_k127_4071920_4 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.00000000005866 74.0
HFD1_k127_4073279_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.3e-310 982.0
HFD1_k127_4073279_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 359.0
HFD1_k127_4073279_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000008207 126.0
HFD1_k127_4073279_3 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000026 100.0
HFD1_k127_4074548_0 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 1.538e-207 652.0
HFD1_k127_4074548_1 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000000000001582 194.0
HFD1_k127_4074548_2 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000002653 91.0
HFD1_k127_4089188_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000228 218.0
HFD1_k127_4089188_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000021 198.0
HFD1_k127_4089188_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000005369 169.0
HFD1_k127_4089188_3 PFAM Secreted repeat of - - - 0.000000000000000000000000000008197 124.0
HFD1_k127_4089188_4 Protein of unknown function (DUF3455) - - - 0.0000000000000004696 86.0
HFD1_k127_4096438_0 CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 395.0
HFD1_k127_4096438_1 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 311.0
HFD1_k127_4096438_2 FMN binding - - - 0.00000000000000000000000000004094 123.0
HFD1_k127_4100422_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 450.0
HFD1_k127_4100422_1 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 347.0
HFD1_k127_4100422_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 303.0
HFD1_k127_4100422_3 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000001788 226.0
HFD1_k127_4100422_4 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000003876 156.0
HFD1_k127_4100422_5 - - - - 0.00000000000003669 81.0
HFD1_k127_4100422_7 ig-like, plexins, transcription factors - - - 0.0003721 53.0
HFD1_k127_4104463_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 566.0
HFD1_k127_4104463_1 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000000000000000000000000004654 186.0
HFD1_k127_4123341_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 594.0
HFD1_k127_4123341_1 Belongs to the acetyltransferase family. ArgA subfamily K03830 - - 0.00000000000000000000000000000000000000000000000004248 187.0
HFD1_k127_4124034_0 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 367.0
HFD1_k127_4124034_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000001728 236.0
HFD1_k127_4124034_2 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000002528 196.0
HFD1_k127_4129934_0 Threonine synthase N terminus K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 615.0
HFD1_k127_4129934_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 520.0
HFD1_k127_4129934_2 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000001386 235.0
HFD1_k127_4129934_3 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000001605 190.0
HFD1_k127_4129934_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000004666 168.0
HFD1_k127_4129934_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000004176 156.0
HFD1_k127_4129934_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000002657 95.0
HFD1_k127_4129934_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000003153 93.0
HFD1_k127_4138459_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 373.0
HFD1_k127_4138459_1 oxidoreductase FAD NAD(P)-binding domain protein K00523,K18248 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002058 250.0
HFD1_k127_4138459_2 PFAM Negative transcriptional regulator K07734 - - 0.000000000000000000000000000000001235 144.0
HFD1_k127_4141646_0 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 463.0
HFD1_k127_4141646_1 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006246 265.0
HFD1_k127_414528_0 Bacterial extracellular solute-binding protein K02027 - - 3.158e-212 666.0
HFD1_k127_414528_1 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 549.0
HFD1_k127_414528_2 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 519.0
HFD1_k127_414528_3 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 512.0
HFD1_k127_414528_4 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 494.0
HFD1_k127_414528_5 Cytochrome c class I K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 384.0
HFD1_k127_414528_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 352.0
HFD1_k127_414528_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 349.0
HFD1_k127_414528_8 PFAM MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 293.0
HFD1_k127_4149347_0 belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 529.0
HFD1_k127_4149347_1 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 376.0
HFD1_k127_4149347_2 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 333.0
HFD1_k127_4166358_0 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 407.0
HFD1_k127_4166358_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 400.0
HFD1_k127_4166358_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 325.0
HFD1_k127_4179162_0 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.06e-244 773.0
HFD1_k127_4179162_1 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 360.0
HFD1_k127_4179162_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000006091 193.0
HFD1_k127_4179162_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000007984 113.0
HFD1_k127_4179162_4 Protein of unknown function (DUF3426) - - - 0.000000000000000000001567 105.0
HFD1_k127_4181174_0 membrane protein terc K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 427.0
HFD1_k127_4181174_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008048 231.0
HFD1_k127_4183335_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.948e-241 749.0
HFD1_k127_4183335_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001554 274.0
HFD1_k127_4183335_2 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000000000000007212 230.0
HFD1_k127_4183335_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000003399 149.0
HFD1_k127_4183335_4 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000002486 81.0
HFD1_k127_4183335_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000001017 64.0
HFD1_k127_4201060_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 447.0
HFD1_k127_4201060_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 323.0
HFD1_k127_4201060_2 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000001333 218.0
HFD1_k127_4210892_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 511.0
HFD1_k127_4210892_1 response regulator - - - 0.0000000000000000000000000000000000000000000000001896 184.0
HFD1_k127_4210892_2 Bacterial transcriptional activator domain - - - 0.0001751 54.0
HFD1_k127_4214366_0 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 268.0
HFD1_k127_4214366_1 Molecular chaperone. Has ATPase activity K04079 - - 0.0000000000000000000000000000000000000000000000000000000000001414 215.0
HFD1_k127_4214366_2 glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000002759 213.0
HFD1_k127_4214366_3 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000000001486 217.0
HFD1_k127_4214366_4 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000009039 175.0
HFD1_k127_4228316_0 type II secretion system protein E K02454 - - 8.849e-211 667.0
HFD1_k127_4228316_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 478.0
HFD1_k127_4228316_2 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 440.0
HFD1_k127_4228316_3 Peptidase family M3 K01284 - 3.4.15.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 296.0
HFD1_k127_4228316_4 general secretion pathway protein K02453 - - 0.000000000000000000000000000000000003224 150.0
HFD1_k127_4239225_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 405.0
HFD1_k127_4239225_1 IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 334.0
HFD1_k127_4239225_2 leucine-zipper of insertion element IS481 - - - 0.00000265 58.0
HFD1_k127_4239225_3 Transposase K07494 - - 0.0005081 44.0
HFD1_k127_4242339_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 486.0
HFD1_k127_4242339_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 410.0
HFD1_k127_4242339_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 353.0
HFD1_k127_4242339_3 squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 323.0
HFD1_k127_4242339_4 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000007387 94.0
HFD1_k127_4255256_0 TonB-linked outer membrane protein, SusC RagA family - - - 1.046e-242 762.0
HFD1_k127_4255697_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.5e-245 762.0
HFD1_k127_4255697_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 541.0
HFD1_k127_4255697_2 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 424.0
HFD1_k127_4255697_3 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008115 403.0
HFD1_k127_4255697_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 375.0
HFD1_k127_4255697_5 UPF0114 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002019 273.0
HFD1_k127_4255697_6 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000003043 186.0
HFD1_k127_4255697_7 there appears to be two types of ribosomal proteins L31 in bacterial genomes K02909 - - 0.00000000000000000000000000000000005071 137.0
HFD1_k127_4255697_8 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 0.0000000000000007621 82.0
HFD1_k127_4268147_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 338.0
HFD1_k127_4268147_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001695 248.0
HFD1_k127_4278953_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 503.0
HFD1_k127_4278953_1 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 323.0
HFD1_k127_4291660_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1022.0
HFD1_k127_4291660_1 Fumarase C C-terminus K01744 - 4.3.1.1 4.553e-266 823.0
HFD1_k127_4291660_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.718e-230 720.0
HFD1_k127_4291660_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 391.0
HFD1_k127_4291660_4 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 327.0
HFD1_k127_4296628_0 Protein of unknown function (DUF1254) - - - 5.508e-234 732.0
HFD1_k127_4296628_1 COG3666 Transposase and inactivated derivatives - - - 1.806e-195 620.0
HFD1_k127_4296628_2 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 391.0
HFD1_k127_4296628_3 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 366.0
HFD1_k127_4296628_4 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002682 273.0
HFD1_k127_4296628_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000001644 174.0
HFD1_k127_4305884_0 peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 351.0
HFD1_k127_4305884_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 357.0
HFD1_k127_4320422_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 606.0
HFD1_k127_4320422_1 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000387 226.0
HFD1_k127_4325288_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 308.0
HFD1_k127_4325288_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004639 274.0
HFD1_k127_4325288_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000003094 241.0
HFD1_k127_4332425_0 cytochrome C oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 603.0
HFD1_k127_4332425_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 584.0
HFD1_k127_4332425_10 Cbb3-type cytochrome oxidase K00407 - - 0.0000000000007957 69.0
HFD1_k127_4332425_2 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 383.0
HFD1_k127_4332425_3 Bacterial regulatory proteins, crp family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 353.0
HFD1_k127_4332425_4 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 331.0
HFD1_k127_4332425_5 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000003819 211.0
HFD1_k127_4332425_6 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000001392 168.0
HFD1_k127_4332425_7 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.0000000000000000000000000000000000000006793 149.0
HFD1_k127_4332425_8 FixH family K09926 - - 0.000000000000000000000001593 109.0
HFD1_k127_4332425_9 - - - - 0.0000000000000000000008901 108.0
HFD1_k127_433490_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 505.0
HFD1_k127_433490_1 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 453.0
HFD1_k127_433490_2 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 305.0
HFD1_k127_433490_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000001537 232.0
HFD1_k127_433490_4 COG4635 Flavodoxin K00230 - 1.3.5.3 0.000000000000000000000000000000000000000001872 162.0
HFD1_k127_433490_5 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000004335 152.0
HFD1_k127_433490_6 Predicted integral membrane protein (DUF2269) - - - 0.0000000000000000000000001212 107.0
HFD1_k127_433490_7 - - - - 0.00000000000000000002962 96.0
HFD1_k127_433490_8 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000006369 82.0
HFD1_k127_4344824_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 535.0
HFD1_k127_4344824_1 Oligopeptidase K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 534.0
HFD1_k127_4344824_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000001005 199.0
HFD1_k127_4344824_3 TRANSCRIPTIONal - - - 0.000000000000000000000000000000000001572 141.0
HFD1_k127_4344824_4 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000275 141.0
HFD1_k127_4344824_5 Glutaredoxin - - - 0.000000000000000000000000000001104 130.0
HFD1_k127_4366938_0 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 529.0
HFD1_k127_4366938_1 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000008211 192.0
HFD1_k127_4370016_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.359e-224 702.0
HFD1_k127_4370016_1 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000004124 101.0
HFD1_k127_4370752_0 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 527.0
HFD1_k127_4370752_1 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001006 257.0
HFD1_k127_4370752_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000111 238.0
HFD1_k127_4370752_3 Diaminopimelate epimerase K01778 - 5.1.1.7 0.000005344 55.0
HFD1_k127_43773_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 442.0
HFD1_k127_43773_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000001164 87.0
HFD1_k127_4377312_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1019.0
HFD1_k127_4377312_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 544.0
HFD1_k127_4377312_2 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 382.0
HFD1_k127_4377312_3 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000009261 185.0
HFD1_k127_4377312_4 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0001028 47.0
HFD1_k127_4388241_0 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000009453 203.0
HFD1_k127_4388241_1 - - - - 0.0000000000000005606 87.0
HFD1_k127_4403177_0 MltA-interacting protein MipA K07274 - - 0.000000000000000000000000000000000000000000000000000000000000001458 228.0
HFD1_k127_4403177_1 - - - - 0.00000000000000000000000000006342 118.0
HFD1_k127_4405403_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 557.0
HFD1_k127_4456089_0 Dienelactone hydrolase family K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002382 251.0
HFD1_k127_4456089_1 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000003758 225.0
HFD1_k127_4456089_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000004276 110.0
HFD1_k127_4489749_0 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 344.0
HFD1_k127_4489749_1 Zinc-binding dehydrogenase K19745 - - 0.0000000000000000000000000004797 122.0
HFD1_k127_4493082_0 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 337.0
HFD1_k127_4493082_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 309.0
HFD1_k127_4493082_2 - - - - 0.0000000000000000000000000000000000000006847 154.0
HFD1_k127_4493082_3 YMGG-like Gly-zipper - - - 0.00001405 48.0
HFD1_k127_4493718_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 580.0
HFD1_k127_4493718_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009791 397.0
HFD1_k127_4493718_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001152 268.0
HFD1_k127_4493718_3 response regulator K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000001469 193.0
HFD1_k127_4493718_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000004643 174.0
HFD1_k127_4493718_5 Peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000000000001674 165.0
HFD1_k127_4493718_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000002244 70.0
HFD1_k127_4496233_0 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001086 270.0
HFD1_k127_4496233_1 GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.0000000000000000000000123 106.0
HFD1_k127_4496233_2 Predicted membrane protein (DUF2339) - - - 0.0000000000000007399 86.0
HFD1_k127_4499970_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 551.0
HFD1_k127_4499970_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 516.0
HFD1_k127_4499970_2 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000003465 215.0
HFD1_k127_4499970_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000001293 191.0
HFD1_k127_450071_0 Glyoxalase bleomycin resistance - - - 0.0000000000000000000000000000000000000000000000001108 188.0
HFD1_k127_450071_1 Acyl-transferase - - - 0.0000000000000000000000000000000003199 139.0
HFD1_k127_4514805_0 NAD+ binding - - - 0.00000000000000000000000001018 125.0
HFD1_k127_4514805_1 - - - - 0.000008457 58.0
HFD1_k127_4523217_0 hydroxypyruvate reductase K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 504.0
HFD1_k127_4523217_1 Transketolase, thiamine diphosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000691 236.0
HFD1_k127_4525945_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 481.0
HFD1_k127_4525945_1 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 325.0
HFD1_k127_4525945_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000001075 257.0
HFD1_k127_4541908_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000004122 133.0
HFD1_k127_4546933_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 358.0
HFD1_k127_4546933_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000001308 260.0
HFD1_k127_4622240_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 1.538e-250 780.0
HFD1_k127_4686443_0 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000001379 164.0
HFD1_k127_4686443_1 Transglycosylase associated protein - - - 0.000000000000000000000000000000000002044 139.0
HFD1_k127_4686443_2 Response regulator receiver - - - 0.000000000000000000000000005329 112.0
HFD1_k127_4689966_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 432.0
HFD1_k127_4689966_1 - - - - 0.00000000000000000006838 102.0
HFD1_k127_4689966_2 Protein of unknown function (DUF1439) - - - 0.0009052 49.0
HFD1_k127_4695653_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.609e-211 666.0
HFD1_k127_4695653_1 GntR family transcriptional regulator K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 354.0
HFD1_k127_4695653_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 295.0
HFD1_k127_4695653_3 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000003739 145.0
HFD1_k127_4695653_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000008313 87.0
HFD1_k127_47121_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 2.671e-243 768.0
HFD1_k127_47121_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 512.0
HFD1_k127_47121_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 334.0
HFD1_k127_47121_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000269 198.0
HFD1_k127_4828808_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005434 245.0
HFD1_k127_4828808_1 COG1226 Kef-type K transport systems K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000002477 245.0
HFD1_k127_4828808_2 Transcriptional regulatory protein, C terminal K07666 - - 0.0000000000000000000000000000000000000002026 161.0
HFD1_k127_4828808_3 transcriptional regulator - - - 0.0009165 42.0
HFD1_k127_4830889_0 Aminotransferase K14261 - - 1.222e-222 698.0
HFD1_k127_4830889_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 541.0
HFD1_k127_4830889_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000005592 227.0
HFD1_k127_4830889_3 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000006054 155.0
HFD1_k127_4841654_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 1.041e-287 894.0
HFD1_k127_4841654_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 496.0
HFD1_k127_4841654_2 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 382.0
HFD1_k127_4841654_3 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 353.0
HFD1_k127_4841654_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000856 73.0
HFD1_k127_4851315_0 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 431.0
HFD1_k127_4851315_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 382.0
HFD1_k127_4859155_0 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000003559 243.0
HFD1_k127_4859155_1 SmpB protein K03664 - - 0.000000000000000000000000000000000000000000000000000000000000007891 220.0
HFD1_k127_4859155_2 oligoketide cyclase lipid transport protein - - - 0.00000000000000000000000000000000000000000000007078 173.0
HFD1_k127_4859155_3 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000003714 162.0
HFD1_k127_4859155_4 Domain of unknown function (DUF4124) - - - 0.000000000000000000005786 99.0
HFD1_k127_4859155_5 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000001828 94.0
HFD1_k127_4862866_0 type II secretion system protein E K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 582.0
HFD1_k127_4862866_1 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 599.0
HFD1_k127_4862866_2 - - - - 0.00000000000000000009083 97.0
HFD1_k127_4862866_3 - - - - 0.00000000000002934 81.0
HFD1_k127_4862866_4 Pilus assembly protein, PilO - - - 0.000000000007431 76.0
HFD1_k127_4863976_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 1.942e-218 697.0
HFD1_k127_4863976_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000006378 229.0
HFD1_k127_4863976_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000001179 137.0
HFD1_k127_4863976_3 PFAM CBS domain containing protein - - - 0.0000000000000000000009512 101.0
HFD1_k127_4863976_4 aldo keto reductase - - - 0.000000000000006419 78.0
HFD1_k127_4867862_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 554.0
HFD1_k127_4867862_1 ABC-type branched-chain amino acid transport systems periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 520.0
HFD1_k127_4867862_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 398.0
HFD1_k127_4867862_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 368.0
HFD1_k127_4867862_4 Histidine kinase K20975 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 335.0
HFD1_k127_4867862_5 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000004871 238.0
HFD1_k127_4867862_6 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000044 147.0
HFD1_k127_4868801_0 TIGRFAM phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
HFD1_k127_4868801_1 Copper resistance protein D - - - 0.0000000000000000000000000000000002373 138.0
HFD1_k127_4868801_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000213 94.0
HFD1_k127_4888135_0 Domain of unknown function (DUF5117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 360.0
HFD1_k127_4888135_1 PFAM PhoH family protein K06217 - - 0.0000000003953 66.0
HFD1_k127_4892027_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.635e-201 628.0
HFD1_k127_4892027_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 407.0
HFD1_k127_4892516_0 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 397.0
HFD1_k127_4892516_1 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005043 270.0
HFD1_k127_4892516_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000663 200.0
HFD1_k127_4892516_3 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.0000000000000000000000000000000000000001455 163.0
HFD1_k127_4892516_4 Protein of unknown function (DUF2630) - - - 0.0000000000000001278 83.0
HFD1_k127_4909373_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 565.0
HFD1_k127_4909373_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000519 187.0
HFD1_k127_4909373_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000006454 168.0
HFD1_k127_4909373_3 Ferrochelatase K01772 - 4.99.1.1,4.99.1.9 0.000000000000008823 74.0
HFD1_k127_491099_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 362.0
HFD1_k127_491099_1 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 299.0
HFD1_k127_491099_2 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000000000000000000000000000000000003686 220.0
HFD1_k127_491099_3 Drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000001251 96.0
HFD1_k127_4911234_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 601.0
HFD1_k127_4911234_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001257 262.0
HFD1_k127_4930405_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 571.0
HFD1_k127_4930405_1 sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 379.0
HFD1_k127_4930405_2 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 305.0
HFD1_k127_4930405_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000119 255.0
HFD1_k127_4930405_4 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000008835 106.0
HFD1_k127_4933581_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 475.0
HFD1_k127_4933581_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 422.0
HFD1_k127_4933581_2 branched-chain amino acid K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000001299 218.0
HFD1_k127_4933581_3 Protein of unknown function (DUF1298) - - - 0.0000000000000256 74.0
HFD1_k127_4935991_0 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 448.0
HFD1_k127_4935991_1 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 433.0
HFD1_k127_4935991_2 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006571 238.0
HFD1_k127_4944747_0 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 450.0
HFD1_k127_4944747_1 Two component transcriptional regulator K07663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 289.0
HFD1_k127_4944747_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000002408 180.0
HFD1_k127_4951816_0 Mg2 and Co2 transporter K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 398.0
HFD1_k127_4951816_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 310.0
HFD1_k127_4951816_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000004452 227.0
HFD1_k127_4951816_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000003273 161.0
HFD1_k127_4951816_4 phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0007058 43.0
HFD1_k127_4969311_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 573.0
HFD1_k127_4969311_1 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 505.0
HFD1_k127_4969311_2 Phosphoribulokinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 501.0
HFD1_k127_4969311_3 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 443.0
HFD1_k127_4969311_4 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000002213 250.0
HFD1_k127_4969311_5 PFAM ribulose bisphosphate carboxylase small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000001747 217.0
HFD1_k127_4978780_0 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 458.0
HFD1_k127_4978780_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000005739 246.0
HFD1_k127_4978780_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000205 107.0
HFD1_k127_4978780_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000005273 93.0
HFD1_k127_5010470_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 386.0
HFD1_k127_5010470_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002065 274.0
HFD1_k127_5010470_2 SMART Transport-associated and nodulation region - - - 0.000000000000000000000000000000000000000000003576 171.0
HFD1_k127_5010470_3 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000008425 123.0
HFD1_k127_5010470_4 LppC putative lipoprotein - - - 0.00000001803 58.0
HFD1_k127_5019278_0 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 470.0
HFD1_k127_5019278_1 Trypsin K08070 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 444.0
HFD1_k127_5019278_10 Protein of unknown function (DUF3999) - - - 0.00000000000002561 87.0
HFD1_k127_5019278_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 351.0
HFD1_k127_5019278_3 nuclear-transcribed mRNA catabolic process, no-go decay - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 336.0
HFD1_k127_5019278_4 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001245 256.0
HFD1_k127_5019278_5 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001014 246.0
HFD1_k127_5019278_6 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000005072 232.0
HFD1_k127_5019278_7 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000003708 192.0
HFD1_k127_5019278_8 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000007048 177.0
HFD1_k127_5019278_9 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000001233 98.0
HFD1_k127_5025616_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 541.0
HFD1_k127_5025616_1 LUD domain K00782 - - 0.000000000000000000000000000007774 119.0
HFD1_k127_5026429_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 5.002e-212 670.0
HFD1_k127_5034798_0 Patatin-like phospholipase - - - 4.617e-218 692.0
HFD1_k127_5034798_1 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 313.0
HFD1_k127_5034798_2 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.00000000000000000000000000000000000000000000000000000000007026 228.0
HFD1_k127_5037165_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 9.726e-273 867.0
HFD1_k127_5037165_1 ABC transporter transmembrane region K06147 - - 1.537e-257 805.0
HFD1_k127_5037165_10 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000004186 205.0
HFD1_k127_5037165_11 MAPEG family - - - 0.00000000000000000000000000000000002552 139.0
HFD1_k127_5037165_12 enzyme binding - - - 0.00000000000000000000000005085 114.0
HFD1_k127_5037165_2 FtsX-like permease family K02004 - - 1.587e-235 754.0
HFD1_k127_5037165_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 549.0
HFD1_k127_5037165_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 469.0
HFD1_k127_5037165_5 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 421.0
HFD1_k127_5037165_6 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 378.0
HFD1_k127_5037165_7 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 337.0
HFD1_k127_5037165_8 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002483 254.0
HFD1_k127_5037165_9 pfam abc K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001006 262.0
HFD1_k127_5057574_0 HlyD family secretion protein K13408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 306.0
HFD1_k127_5057574_1 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000003694 174.0
HFD1_k127_5057574_2 Iron-sulphur cluster assembly - - - 0.00000000000000000000007784 104.0
HFD1_k127_5057574_3 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000002417 89.0
HFD1_k127_5076015_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000006414 248.0
HFD1_k127_5076015_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000005174 234.0
HFD1_k127_5076015_2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000000001642 154.0
HFD1_k127_5076015_3 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.0000000000000000000000000000000124 130.0
HFD1_k127_5076015_4 - - - - 0.0000000000000000001161 100.0
HFD1_k127_5077545_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 488.0
HFD1_k127_5077545_1 - - - - 0.000000000000000000000000000000000009091 143.0
HFD1_k127_5077545_2 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.000004807 51.0
HFD1_k127_5078523_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 2.319e-223 700.0
HFD1_k127_5078523_1 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 542.0
HFD1_k127_5092147_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 435.0
HFD1_k127_5092147_1 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000008814 149.0
HFD1_k127_5092147_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000002081 127.0
HFD1_k127_5096917_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 368.0
HFD1_k127_5098879_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 501.0
HFD1_k127_5098879_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000005779 232.0
HFD1_k127_5109674_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 5.35e-281 874.0
HFD1_k127_5109674_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 420.0
HFD1_k127_5109674_2 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.000001069 53.0
HFD1_k127_5114076_0 permease K03303 - - 2.944e-306 942.0
HFD1_k127_5114076_1 - - - - 0.000000000002485 71.0
HFD1_k127_5125311_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000009231 222.0
HFD1_k127_5125311_1 Flavodoxin domain K00230 GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.3 0.00000000000000000000000000000000000000000000000002031 187.0
HFD1_k127_5125311_2 Prokaryotic cytochrome b561 - - - 0.0000000000000000000764 93.0
HFD1_k127_5127318_0 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 496.0
HFD1_k127_5127318_1 Ankyrin repeats (3 copies) K06867,K21440 - - 0.0000000000000000000000000000000000000006794 154.0
HFD1_k127_5136056_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 528.0
HFD1_k127_5136056_1 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 329.0
HFD1_k127_51365_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 516.0
HFD1_k127_51365_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 440.0
HFD1_k127_5153545_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 497.0
HFD1_k127_5153545_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000007175 126.0
HFD1_k127_5179786_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 569.0
HFD1_k127_5179786_1 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 475.0
HFD1_k127_5179786_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 425.0
HFD1_k127_5179786_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 326.0
HFD1_k127_518428_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000243 297.0
HFD1_k127_518428_1 response regulator receiver K07659 - - 0.000000000000006068 75.0
HFD1_k127_5228582_0 Cyclase dehydrase - - - 0.0000000000000000000000000000000000001872 146.0
HFD1_k127_5228582_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000001846 143.0
HFD1_k127_5228582_2 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000001712 113.0
HFD1_k127_5228582_3 ATP synthase subunit D K02120 - - 0.000000000000000001008 91.0
HFD1_k127_5228582_4 PFAM cytochrome c, class I K08738 - - 0.000000000000000001691 91.0
HFD1_k127_5228582_5 Cytochrome c K08738 - - 0.00000001153 59.0
HFD1_k127_5238692_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 434.0
HFD1_k127_5238692_1 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 301.0
HFD1_k127_5238692_2 cyclic nucleotide binding K10914 - - 0.00000000000000000008938 96.0
HFD1_k127_5238692_3 DegT/DnrJ/EryC1/StrS aminotransferase family K01740 - 2.5.1.49 0.000000000000002461 86.0
HFD1_k127_5238692_4 CBS domain containing protein - - - 0.000001013 56.0
HFD1_k127_5242426_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.452e-249 784.0
HFD1_k127_5242426_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002706 258.0
HFD1_k127_5242426_4 - - - - 0.00002947 55.0
HFD1_k127_5250357_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.469e-235 741.0
HFD1_k127_5250357_1 DNA-directed DNA polymerase activity K02347,K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000003826 239.0
HFD1_k127_5250357_2 Sporulation related domain - - - 0.0000000000000000000000000000000001938 139.0
HFD1_k127_5250357_3 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000004443 107.0
HFD1_k127_5252471_0 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 388.0
HFD1_k127_5252471_1 Ammonium transporter K03320,K06580 - - 0.0000000000000000000000000000003686 128.0
HFD1_k127_528031_0 Phage tail sheath C-terminal domain K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 350.0
HFD1_k127_528031_1 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000006904 213.0
HFD1_k127_528031_2 T4-like virus tail tube protein gp19 - - - 0.000001723 55.0
HFD1_k127_528719_0 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 392.0
HFD1_k127_528719_1 - - - - 0.00000000000000000000000000003941 122.0
HFD1_k127_528719_3 peptidoglycan-binding protein, lysm - - - 0.0000000000000000005491 91.0
HFD1_k127_5329494_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.114e-206 649.0
HFD1_k127_5329494_1 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000000009231 222.0
HFD1_k127_5329494_2 Modulates RecA activity K03565 - - 0.00000000000000000000000000006284 122.0
HFD1_k127_5345996_0 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 2.307e-260 807.0
HFD1_k127_5345996_1 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 403.0
HFD1_k127_5345996_2 PspC domain - - - 0.000000000000003561 76.0
HFD1_k127_5351541_0 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000001551 214.0
HFD1_k127_5360344_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 456.0
HFD1_k127_5386518_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 530.0
HFD1_k127_5386518_1 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000005449 195.0
HFD1_k127_5386518_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000009208 157.0
HFD1_k127_5386518_3 Cell division and transport-associated protein TolA K03646 - - 0.0000001062 55.0
HFD1_k127_5399537_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1218.0
HFD1_k127_5399537_1 C-terminal region of band_7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 456.0
HFD1_k127_5399537_2 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002538 274.0
HFD1_k127_5399537_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000007244 239.0
HFD1_k127_5399537_4 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000002621 168.0
HFD1_k127_5399537_5 - - - - 0.000000000000000000000000000000000444 134.0
HFD1_k127_5399537_6 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000000000000000000004488 124.0
HFD1_k127_5399537_7 SnoaL-like domain - - - 0.000000000000000000000000000005272 123.0
HFD1_k127_5416728_0 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 492.0
HFD1_k127_5416728_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000006902 150.0
HFD1_k127_5416728_3 Cytochrome c - - - 0.00000000000001871 77.0
HFD1_k127_5416728_4 Histidine triad (Hit) protein K02503 - - 0.000004552 54.0
HFD1_k127_5453250_0 PFAM cytochrome c class I K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 539.0
HFD1_k127_5453250_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 530.0
HFD1_k127_5453250_2 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001148 263.0
HFD1_k127_5453250_3 Domain of Unknown function (DUF542) - - - 0.000000000000000000000000000000000000000000000000000000000000000001718 238.0
HFD1_k127_5502437_0 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 363.0
HFD1_k127_5502437_1 PFAM glycosyl transferase family 9 - - - 0.0000000000000003626 84.0
HFD1_k127_5502437_2 Carbamoyltransferase C-terminus K00612 - - 0.00000000000008366 75.0
HFD1_k127_5590397_0 Belongs to the malate synthase family K01638 - 2.3.3.9 3.899e-295 912.0
HFD1_k127_5590397_1 CBS domain - - - 0.000000000000000000000000001378 114.0
HFD1_k127_5625752_0 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 430.0
HFD1_k127_5625752_1 cellular response to DNA damage stimulus K07340 - - 0.00000000000000000000000000006617 123.0
HFD1_k127_5629425_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 1.86e-210 657.0
HFD1_k127_5629425_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000007908 156.0
HFD1_k127_5629539_0 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 362.0
HFD1_k127_5629539_1 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002066 277.0
HFD1_k127_5629539_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001544 260.0
HFD1_k127_5634029_0 PFAM transposase mutator type - - - 1.369e-202 639.0
HFD1_k127_5634029_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 384.0
HFD1_k127_5634029_2 transposase activity - - - 0.0001133 44.0
HFD1_k127_5641670_0 Multicopper oxidase - - - 4.403e-197 637.0
HFD1_k127_5641670_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001379 228.0
HFD1_k127_5641670_2 Sulfatase K01130 - 3.1.6.1 0.00000000001003 68.0
HFD1_k127_5641670_3 arylsulfatase activity - - - 0.00000000001942 69.0
HFD1_k127_5642172_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 1.252e-198 664.0
HFD1_k127_5655353_0 TonB-dependent receptor - - - 2.954e-250 806.0
HFD1_k127_5655353_1 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 604.0
HFD1_k127_5655353_2 TRANSCRIPTIONal - - - 0.000000000000000001237 87.0
HFD1_k127_5658460_0 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 531.0
HFD1_k127_5658460_1 carnitine dehydratase K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 496.0
HFD1_k127_5658460_2 cysteine dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000006315 226.0
HFD1_k127_5658460_3 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000237 205.0
HFD1_k127_5673595_0 Histidine kinase K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 548.0
HFD1_k127_5673595_1 Transcriptional regulatory protein, C terminal K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 356.0
HFD1_k127_5673595_2 Protein conserved in bacteria K09924 - - 0.0000000000000000000000000000000000000008003 158.0
HFD1_k127_5675540_0 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 344.0
HFD1_k127_5675540_1 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000003264 216.0
HFD1_k127_5683621_0 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 484.0
HFD1_k127_5683621_1 Homocysteine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 440.0
HFD1_k127_5683621_2 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 345.0
HFD1_k127_5683621_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 340.0
HFD1_k127_5683621_4 DoxX K15977 - - 0.0000000000000000000000000000000000004626 141.0
HFD1_k127_5687981_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 419.0
HFD1_k127_5687981_1 thioesterase K07107 - - 0.00000000000000000000000000000000002324 139.0
HFD1_k127_5687981_2 Diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000000000000001007 117.0
HFD1_k127_5690239_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 4.111e-254 790.0
HFD1_k127_5690239_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 381.0
HFD1_k127_5690239_2 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000001954 109.0
HFD1_k127_5690239_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001018 106.0
HFD1_k127_5692086_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 314.0
HFD1_k127_5692086_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002961 278.0
HFD1_k127_5701432_0 Flavin containing amine oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 518.0
HFD1_k127_5701432_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 494.0
HFD1_k127_5701432_2 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 332.0
HFD1_k127_5701432_3 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 325.0
HFD1_k127_5701432_4 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 303.0
HFD1_k127_5701432_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002332 235.0
HFD1_k127_5701432_6 Chalcone isomerase-like - - - 0.0000000000000000000000000000000006382 141.0
HFD1_k127_5706132_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 522.0
HFD1_k127_5706132_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002149 261.0
HFD1_k127_5706132_2 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000002469 212.0
HFD1_k127_5706132_3 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000001083 196.0
HFD1_k127_5706132_4 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000001363 148.0
HFD1_k127_5706132_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000001925 143.0
HFD1_k127_570632_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 425.0
HFD1_k127_570632_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 391.0
HFD1_k127_570632_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000003411 234.0
HFD1_k127_570632_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000005356 154.0
HFD1_k127_570632_4 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000003533 63.0
HFD1_k127_5714274_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 444.0
HFD1_k127_5716169_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 438.0
HFD1_k127_5716169_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 389.0
HFD1_k127_5716169_2 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 325.0
HFD1_k127_5716169_3 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.0000000000000000000000000000000000000009621 151.0
HFD1_k127_5724326_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 382.0
HFD1_k127_5724326_1 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000001717 200.0
HFD1_k127_5730451_0 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 482.0
HFD1_k127_5730451_1 Bacterial periplasmic substrate-binding proteins K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 437.0
HFD1_k127_5730451_2 Amino acid ABC transporter substrate-binding protein K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 332.0
HFD1_k127_5730451_3 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 302.0
HFD1_k127_5747417_0 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 331.0
HFD1_k127_5747417_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000005392 235.0
HFD1_k127_5747417_2 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000002926 228.0
HFD1_k127_5747417_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000005236 95.0
HFD1_k127_5747499_0 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 574.0
HFD1_k127_5747499_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000002698 147.0
HFD1_k127_5749277_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 437.0
HFD1_k127_5749277_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 328.0
HFD1_k127_5749277_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000008545 224.0
HFD1_k127_5749277_3 Psort location Extracellular, score K07126 - - 0.00000000000000000000000000000000000000000000000000000000619 205.0
HFD1_k127_5749277_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000001191 204.0
HFD1_k127_5749277_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000003072 188.0
HFD1_k127_5749277_6 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000003118 160.0
HFD1_k127_5749277_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000000000001586 142.0
HFD1_k127_5749277_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000002494 103.0
HFD1_k127_5751197_0 MmgE/PrpD family - - - 9.689e-201 656.0
HFD1_k127_5751197_1 COG1960 Acyl-CoA dehydrogenases K18244 - - 5.674e-197 619.0
HFD1_k127_5751197_10 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000749 220.0
HFD1_k127_5751197_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000009819 195.0
HFD1_k127_5751197_12 - - - - 0.0000000000000000000000000000000000000008028 154.0
HFD1_k127_5751197_2 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component K11690 - - 1.211e-195 619.0
HFD1_k127_5751197_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 563.0
HFD1_k127_5751197_4 carbohydrate transport K11688,K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 393.0
HFD1_k127_5751197_5 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 393.0
HFD1_k127_5751197_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 373.0
HFD1_k127_5751197_7 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001355 294.0
HFD1_k127_5751197_8 dehydratase K18290 - 4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006004 267.0
HFD1_k127_5751197_9 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000004367 243.0
HFD1_k127_5755219_0 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 611.0
HFD1_k127_5755219_1 ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 437.0
HFD1_k127_5756452_0 Alcohol dehydrogenase GroES-like domain K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 553.0
HFD1_k127_5756452_1 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 400.0
HFD1_k127_5756452_2 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000009607 103.0
HFD1_k127_5758285_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 598.0
HFD1_k127_5758285_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 486.0
HFD1_k127_5758285_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 347.0
HFD1_k127_5758285_3 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000008391 153.0
HFD1_k127_5759057_0 Alkyl hydroperoxide reductase K03387 - - 9.056e-266 825.0
HFD1_k127_5759057_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000002941 190.0
HFD1_k127_5765509_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002853 257.0
HFD1_k127_5765509_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000002692 151.0
HFD1_k127_5765509_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000005074 126.0
HFD1_k127_5767121_0 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03669 - - 1.271e-241 771.0
HFD1_k127_5767121_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 588.0
HFD1_k127_5767121_2 Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001789 273.0
HFD1_k127_5767121_3 - - - - 0.00000000000000000000000000000000000000000000000000000001954 211.0
HFD1_k127_5767121_4 - - - - 0.0000000000003273 74.0
HFD1_k127_5770294_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 533.0
HFD1_k127_5770294_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 468.0
HFD1_k127_5770294_2 competence protein COMEC - - - 0.0000000000000000000000000000000000000000000000000000000000000000004501 239.0
HFD1_k127_5770294_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001576 228.0
HFD1_k127_5779847_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 542.0
HFD1_k127_5779847_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 383.0
HFD1_k127_5779847_2 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000000000000000000000008695 190.0
HFD1_k127_5785133_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 479.0
HFD1_k127_5785133_1 Domain of unknown function (DUF4124) - - - 0.00000000000000000001478 99.0
HFD1_k127_5790012_0 Highly conserved protein containing a thioredoxin domain K06888 - - 5.011e-232 736.0
HFD1_k127_5790012_1 Domain of unknown function (DUF4398) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002368 280.0
HFD1_k127_5790012_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008598 244.0
HFD1_k127_5790012_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000001158 203.0
HFD1_k127_5790012_4 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000002005 166.0
HFD1_k127_5790012_5 Domain of unknown function (DUF4398) - - - 0.0000000001549 66.0
HFD1_k127_5791286_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 474.0
HFD1_k127_5791286_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000001977 201.0
HFD1_k127_5791286_2 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000003124 141.0
HFD1_k127_5804537_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 436.0
HFD1_k127_5804537_1 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 402.0
HFD1_k127_5804537_2 PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002539 245.0
HFD1_k127_5804537_3 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000002973 147.0
HFD1_k127_5804537_4 Sodium Bile acid symporter family - - - 0.000000000000000000000000000003907 134.0
HFD1_k127_5804537_5 YMGG-like Gly-zipper - - - 0.00000000001935 68.0
HFD1_k127_5804537_6 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.00000001514 63.0
HFD1_k127_5807375_0 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 499.0
HFD1_k127_5807375_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 467.0
HFD1_k127_5807375_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 443.0
HFD1_k127_5807375_3 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002705 253.0
HFD1_k127_5807375_4 competence protein - - - 0.000000000000000000000000000000008691 143.0
HFD1_k127_5812096_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.109e-199 632.0
HFD1_k127_5812096_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 297.0
HFD1_k127_5812096_2 ATP synthase subunit D K02120 - - 0.00000001352 66.0
HFD1_k127_5812720_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003396 276.0
HFD1_k127_5812720_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000002707 226.0
HFD1_k127_5812720_2 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000008046 215.0
HFD1_k127_5832112_0 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000001123 189.0
HFD1_k127_5832112_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000004215 126.0
HFD1_k127_5832112_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000008487 108.0
HFD1_k127_5839577_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.934e-210 662.0
HFD1_k127_5839577_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 360.0
HFD1_k127_5839577_2 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001199 278.0
HFD1_k127_5850748_0 Peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 608.0
HFD1_k127_5850748_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 322.0
HFD1_k127_5850748_10 cytochrome K17230 - - 0.000000000000001117 90.0
HFD1_k127_5850748_11 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.00000000000003027 83.0
HFD1_k127_5850748_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 326.0
HFD1_k127_5850748_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001179 264.0
HFD1_k127_5850748_4 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000004846 239.0
HFD1_k127_5850748_5 - - - - 0.0000000000000000000000000000000000000000000000001076 186.0
HFD1_k127_5850748_6 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000004907 198.0
HFD1_k127_5850748_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000008843 157.0
HFD1_k127_5850748_8 Cytochrome c - - - 0.0000000000000000000000000000000402 136.0
HFD1_k127_5850748_9 Cytochrome c - - - 0.0000000000000000000007302 110.0
HFD1_k127_5893280_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1418.0
HFD1_k127_5893280_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 509.0
HFD1_k127_5893280_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 326.0
HFD1_k127_5893280_3 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000002255 275.0
HFD1_k127_5893280_4 OmpA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000005683 233.0
HFD1_k127_5893280_5 AsmA family - - - 0.00000000000000000000000000000000000000000000000000000000000000001148 241.0
HFD1_k127_5893280_6 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000008651 125.0
HFD1_k127_5896087_1 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000002805 94.0
HFD1_k127_5913683_0 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 566.0
HFD1_k127_5913683_1 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000002522 201.0
HFD1_k127_5919897_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 513.0
HFD1_k127_5919897_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 438.0
HFD1_k127_5922778_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 535.0
HFD1_k127_5922778_1 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 360.0
HFD1_k127_5922778_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000003914 158.0
HFD1_k127_5922778_3 seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing K05808 - - 0.000000000000000000000000000000001083 134.0
HFD1_k127_5924878_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 411.0
HFD1_k127_5924878_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 382.0
HFD1_k127_5924878_2 MerR HTH family regulatory protein K18997 - - 0.000000000000000002873 89.0
HFD1_k127_5924878_3 DnaJ C terminal domain K05516 - - 0.00000000000001496 74.0
HFD1_k127_5925518_0 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 512.0
HFD1_k127_5925518_1 Peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 344.0
HFD1_k127_5925518_2 Dehydrogenase K00043 - 1.1.1.61 0.000000000009485 69.0
HFD1_k127_5930843_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.964e-218 680.0
HFD1_k127_5930843_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 301.0
HFD1_k127_5930843_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004472 239.0
HFD1_k127_5930843_3 Iron-sulfur cluster assembly transcription factor K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000209 233.0
HFD1_k127_5930843_4 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000000000005504 189.0
HFD1_k127_5930843_5 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000774 183.0
HFD1_k127_5930843_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000001513 174.0
HFD1_k127_5930843_7 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000009099 71.0
HFD1_k127_5931746_0 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 466.0
HFD1_k127_5931746_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 297.0
HFD1_k127_5931746_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000001623 226.0
HFD1_k127_5931746_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000002968 197.0
HFD1_k127_5931746_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000004286 133.0
HFD1_k127_5931746_5 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000006264 116.0
HFD1_k127_5942262_0 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 386.0
HFD1_k127_5942262_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000004033 132.0
HFD1_k127_5942262_2 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000002098 110.0
HFD1_k127_5974356_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 3.093e-239 744.0
HFD1_k127_5974356_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000003275 164.0
HFD1_k127_5975735_0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000006761 113.0
HFD1_k127_6024366_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 6.571e-298 922.0
HFD1_k127_6024366_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 308.0
HFD1_k127_6024366_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.000000000000000000000000000000000000000000000000002247 183.0
HFD1_k127_6036105_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 424.0
HFD1_k127_6036105_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 415.0
HFD1_k127_6036105_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 348.0
HFD1_k127_6036105_3 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 311.0
HFD1_k127_6036105_4 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001345 267.0
HFD1_k127_6036105_5 Protein of unknown function (DUF721) - - - 0.0009008 48.0
HFD1_k127_6037039_0 Polyphosphate kinase middle domain K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 510.0
HFD1_k127_6037039_1 NADP oxidoreductase coenzyme F420-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 317.0
HFD1_k127_6037039_2 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 308.0
HFD1_k127_6037039_3 phosphohistidine phosphatase K08296 - - 0.0000000000000000000000000000000004551 150.0
HFD1_k127_6038331_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 377.0
HFD1_k127_6038331_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 342.0
HFD1_k127_6038331_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000001942 198.0
HFD1_k127_6040708_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 520.0
HFD1_k127_6040708_1 Transcriptional regulator K03603,K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000023 229.0
HFD1_k127_604882_0 NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 529.0
HFD1_k127_6056387_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 456.0
HFD1_k127_6056387_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003123 268.0
HFD1_k127_6087446_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000001169 268.0
HFD1_k127_6087446_1 Belongs to the acetyltransferase family. ArgA subfamily K03830 - - 0.00000000000000000000000000000000000000000000000001371 187.0
HFD1_k127_6087446_2 Saccharopine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000001558 183.0
HFD1_k127_6109156_0 COG1670 Acetyltransferases, including N-acetylases of - - - 0.0000000000000000000000000000000000000000000000000000000003342 210.0
HFD1_k127_6109156_1 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000006028 198.0
HFD1_k127_6109156_2 Na+ dependent nucleoside transporter C-terminus K03317 - - 0.0000000000000000003048 88.0
HFD1_k127_6109156_3 - - - - 0.000000002674 60.0
HFD1_k127_6111920_0 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 3.836e-275 854.0
HFD1_k127_6111920_1 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 511.0
HFD1_k127_6111920_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 420.0
HFD1_k127_6132722_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 577.0
HFD1_k127_6132722_1 ornithine cyclodeaminase K01750 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 4.3.1.12 0.000000000000000000000000000000000000000000000000001931 186.0
HFD1_k127_6141993_0 Belongs to the enoyl-CoA hydratase isomerase family K19640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 365.0
HFD1_k127_6141993_1 - - - - 0.00000000005981 72.0
HFD1_k127_6152512_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 475.0
HFD1_k127_6152512_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000007405 201.0
HFD1_k127_6164662_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002186 259.0
HFD1_k127_6164662_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000672 259.0
HFD1_k127_6164662_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000009191 240.0
HFD1_k127_6164662_3 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000003018 209.0
HFD1_k127_6164662_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000491 158.0
HFD1_k127_6164662_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000286 159.0
HFD1_k127_6227155_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 604.0
HFD1_k127_6227155_1 PFAM Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003585 278.0
HFD1_k127_6227155_2 - - - - 0.0000000000000002593 87.0
HFD1_k127_6227155_3 - - - - 0.0000001135 56.0
HFD1_k127_6284_0 Peptidase family M20/M25/M40 K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 317.0
HFD1_k127_6288899_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 332.0
HFD1_k127_6288899_1 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000000000008026 201.0
HFD1_k127_6288899_2 cytochrome - - - 0.00000000000000000000001392 102.0
HFD1_k127_6293679_0 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 389.0
HFD1_k127_6293679_1 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.00000000000000000000001309 101.0
HFD1_k127_6293679_2 acyl-coA-binding protein - - - 0.00000000000000000003825 90.0
HFD1_k127_6293679_3 polyhydroxyalkanoic acid system protein - - - 0.00000000000005185 84.0
HFD1_k127_6297118_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 5.973e-208 656.0
HFD1_k127_6297118_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 417.0
HFD1_k127_6297118_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000000007583 213.0
HFD1_k127_6315989_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 331.0
HFD1_k127_6315989_1 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000000000000005286 217.0
HFD1_k127_6315989_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 GO:0001130,GO:0003674,GO:0003700,GO:0003824,GO:0003908,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006355,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016740,GO:0016741,GO:0018125,GO:0018193,GO:0018198,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044728,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070988,GO:0071704,GO:0080090,GO:0080111,GO:0090304,GO:0140110,GO:1901360,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 2.1.1.63 0.0000000000000000000000000000000000000000004365 166.0
HFD1_k127_6404663_0 Sulfatase K01130 - 3.1.6.1 0.0 1429.0
HFD1_k127_6404663_1 Sulfatase K01130 - 3.1.6.1 0.0 1404.0
HFD1_k127_6404663_10 - - - - 0.0008199 48.0
HFD1_k127_6404663_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000003819 215.0
HFD1_k127_6404663_3 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000004594 210.0
HFD1_k127_6404663_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000002274 220.0
HFD1_k127_6404663_5 response regulator - - - 0.0000000000000000000000000000000000000000000001465 192.0
HFD1_k127_6404663_7 - - - - 0.000000000000000000000000000000001949 133.0
HFD1_k127_6404663_8 response regulator - - - 0.0000000000000002993 83.0
HFD1_k127_6404663_9 radical SAM domain protein K06871 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 - 0.000000000002467 70.0
HFD1_k127_6438071_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 434.0
HFD1_k127_6438071_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000307 150.0
HFD1_k127_6438278_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1052.0
HFD1_k127_6438278_1 FAD-dependent pyridine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 529.0
HFD1_k127_6438278_2 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 304.0
HFD1_k127_6438278_3 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 291.0
HFD1_k127_6438278_4 PFAM thiamineS protein - - - 0.0000000000000000000000000007405 114.0
HFD1_k127_6438278_5 - - - - 0.000000000008126 69.0
HFD1_k127_6438278_6 PFAM glycosyl transferase family 39 - - - 0.000000002142 59.0
HFD1_k127_6438958_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 352.0
HFD1_k127_6438958_1 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000734 151.0
HFD1_k127_6440149_0 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 481.0
HFD1_k127_6440149_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 422.0
HFD1_k127_6440149_2 demethylmenaquinone methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 374.0
HFD1_k127_6440149_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000003186 217.0
HFD1_k127_6447136_0 nucleoside-diphosphate sugar epimerase - - - 1.395e-200 635.0
HFD1_k127_6447136_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000001679 174.0
HFD1_k127_6447136_2 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000001471 133.0
HFD1_k127_6447136_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.000004706 51.0
HFD1_k127_6448526_0 oxidoreductase activity - - - 6.834e-256 797.0
HFD1_k127_6458392_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003056 274.0
HFD1_k127_6463763_0 - - - - 0.000003969 59.0
HFD1_k127_6466842_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001642 271.0
HFD1_k127_6466842_1 Response regulator receiver - - - 0.000000000000000000000000000000000656 138.0
HFD1_k127_6468001_0 CoA binding domain K09181 - - 1.79e-205 662.0
HFD1_k127_6468001_1 TraB family K09973 - - 0.000000000000000000000000000000000000000001291 171.0
HFD1_k127_6474469_0 Extracellular solute-binding protein, family 5 middle family protein 22 - - - 4.166e-298 932.0
HFD1_k127_6474469_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 3.644e-242 764.0
HFD1_k127_6474469_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 565.0
HFD1_k127_6474469_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 411.0
HFD1_k127_6475865_0 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 366.0
HFD1_k127_6475865_1 Pfam:DUF59 K02612 - - 0.0000000000000000000000000000000000000000000000000000000000000001829 236.0
HFD1_k127_6475865_2 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.000000000000000000000000000000000000000000000000000033 189.0
HFD1_k127_6475865_3 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.0000000000000000000000000000000000000000000000000001563 189.0
HFD1_k127_6475865_4 TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit K02609 - 1.14.13.149 0.000000000000000000000000001035 112.0
HFD1_k127_64770_0 Cysteine-rich domain - - - 4.469e-206 651.0
HFD1_k127_64770_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 446.0
HFD1_k127_64770_2 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 329.0
HFD1_k127_64770_3 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001343 265.0
HFD1_k127_64770_4 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001311 254.0
HFD1_k127_64770_5 TM2 domain - - - 0.0000000000000347 75.0
HFD1_k127_6478147_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.536e-248 777.0
HFD1_k127_6478601_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 438.0
HFD1_k127_6478601_1 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 408.0
HFD1_k127_6478601_2 Signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 398.0
HFD1_k127_6478601_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 301.0
HFD1_k127_6478601_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001643 293.0
HFD1_k127_6478601_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000461 256.0
HFD1_k127_6478601_6 - - - - 0.000000000000000003681 85.0
HFD1_k127_6479065_0 PFAM transposase, mutator K07493 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002367 294.0
HFD1_k127_6483124_0 Rhodanese Homology Domain K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 411.0
HFD1_k127_6483124_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 312.0
HFD1_k127_6483124_2 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000398 256.0
HFD1_k127_6483124_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000009465 241.0
HFD1_k127_6483124_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.0000003592 53.0
HFD1_k127_6486233_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1119.0
HFD1_k127_6486233_1 acyl-CoA dehydrogenase - - - 1.931e-267 833.0
HFD1_k127_6486233_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 281.0
HFD1_k127_649067_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1037.0
HFD1_k127_649067_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 408.0
HFD1_k127_649067_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000883 205.0
HFD1_k127_6494385_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 417.0
HFD1_k127_6494385_1 Elements of external origin - - - 0.000000000000000000000000000175 123.0
HFD1_k127_6494385_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000006982 56.0
HFD1_k127_6495456_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 276.0
HFD1_k127_6495456_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000943 263.0
HFD1_k127_6495456_2 FMN_bind K00348 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000005636 220.0
HFD1_k127_6495456_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 0.0000000000000000008065 87.0
HFD1_k127_6501053_0 Selenium-binding protein K17285 - - 1.58e-211 665.0
HFD1_k127_6501053_1 SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000004668 195.0
HFD1_k127_6501053_2 modulator of DNA gyrase K03568 - - 0.0000000000000000001524 87.0
HFD1_k127_6503243_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 413.0
HFD1_k127_6503243_1 Phospholipase D Active site motif K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 388.0
HFD1_k127_6503243_2 Mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000001008 246.0
HFD1_k127_6503243_3 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000003008 207.0
HFD1_k127_6503243_4 YceI-like domain K12262 - - 0.0000000000000000000000005871 106.0
HFD1_k127_6503600_0 PFAM Ion transport protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 343.0
HFD1_k127_6503600_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 299.0
HFD1_k127_6506347_0 Putative diguanylate phosphodiesterase - - - 0.0 1167.0
HFD1_k127_6506347_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 457.0
HFD1_k127_6514443_0 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 620.0
HFD1_k127_6514443_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 383.0
HFD1_k127_6514443_2 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 323.0
HFD1_k127_6514443_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000003612 131.0
HFD1_k127_6514820_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 3.396e-299 937.0
HFD1_k127_6514820_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 425.0
HFD1_k127_6514820_10 Udp N-acetylglucosamine O-acyltransferase; Domain 2 K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000242 252.0
HFD1_k127_6514820_11 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000005425 219.0
HFD1_k127_6514820_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001869 229.0
HFD1_k127_6514820_13 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000001783 199.0
HFD1_k127_6514820_14 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000002059 195.0
HFD1_k127_6514820_15 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000004562 186.0
HFD1_k127_6514820_2 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 426.0
HFD1_k127_6514820_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 409.0
HFD1_k127_6514820_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 397.0
HFD1_k127_6514820_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 334.0
HFD1_k127_6514820_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 323.0
HFD1_k127_6514820_7 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 287.0
HFD1_k127_6514820_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002064 275.0
HFD1_k127_6514820_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 258.0
HFD1_k127_6517983_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.011e-216 689.0
HFD1_k127_6517983_1 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 610.0
HFD1_k127_6517983_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 405.0
HFD1_k127_6517983_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000001044 239.0
HFD1_k127_6517983_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000003643 245.0
HFD1_k127_6518001_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 4.61e-267 831.0
HFD1_k127_6518001_1 PFAM aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000001399 171.0
HFD1_k127_6521408_0 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 298.0
HFD1_k127_6521408_1 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001002 281.0
HFD1_k127_6521408_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000001165 237.0
HFD1_k127_6531721_0 peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 516.0
HFD1_k127_6531721_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 356.0
HFD1_k127_6531721_2 Serine aminopeptidase, S33 - - - 0.00000000006121 68.0
HFD1_k127_6535413_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 2082.0
HFD1_k127_6535413_1 nitrite transporter K02575 - - 1.579e-302 958.0
HFD1_k127_6535413_2 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 1.422e-284 880.0
HFD1_k127_6535413_3 Major Facilitator Superfamily K02575 - - 3.924e-211 662.0
HFD1_k127_6535413_4 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 412.0
HFD1_k127_6535413_5 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 407.0
HFD1_k127_6535413_6 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
HFD1_k127_6535413_7 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000001951 256.0
HFD1_k127_6535413_8 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000001593 160.0
HFD1_k127_6543210_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 543.0
HFD1_k127_6543210_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 450.0
HFD1_k127_6543210_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 326.0
HFD1_k127_6543210_3 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000009735 212.0
HFD1_k127_6543210_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000266 84.0
HFD1_k127_6543210_5 Transport permease protein K09694 - - 0.000000004609 59.0
HFD1_k127_6545723_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000002196 236.0
HFD1_k127_6545723_1 - - - - 0.000000000000000000000003512 112.0
HFD1_k127_6555588_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 546.0
HFD1_k127_6555588_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000209 169.0
HFD1_k127_6555588_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000005718 66.0
HFD1_k127_6555700_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000003376 243.0
HFD1_k127_6555700_1 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000009256 216.0
HFD1_k127_6555700_2 Redoxin - - - 0.000000000000000000000000000000000000000000000000004402 189.0
HFD1_k127_6555700_3 TPM domain - - - 0.00000000000000000000000000000000000000000000000001338 184.0
HFD1_k127_6555700_4 Domain of unknown function (DUF4266) - - - 0.000000000000000000004894 94.0
HFD1_k127_6564997_0 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 2.073e-198 636.0
HFD1_k127_6564997_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 417.0
HFD1_k127_6564997_2 synthetase K01907 - 6.2.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 296.0
HFD1_k127_6564997_3 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002084 257.0
HFD1_k127_6564997_4 PFAM Thioredoxin K00384 - 1.8.1.9 0.000000000000000000000001485 117.0
HFD1_k127_6564997_5 Glycine zipper 2TM domain K04062 - - 0.000000000009157 67.0
HFD1_k127_6564997_6 Protein of unknown function (DUF3014) - - - 0.00005972 45.0
HFD1_k127_6580543_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 362.0
HFD1_k127_6580543_1 Guanyl-specific ribonuclease Sa K01167 - 3.1.27.3 0.00000000000000000000000000000000000335 141.0
HFD1_k127_6580543_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000001172 126.0
HFD1_k127_6580543_3 PFAM Barstar (barnase inhibitor) - - - 0.00000000000000002221 89.0
HFD1_k127_6585315_0 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 592.0
HFD1_k127_6585315_1 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 545.0
HFD1_k127_6585315_2 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 337.0
HFD1_k127_6585315_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000002936 195.0
HFD1_k127_6585966_0 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 605.0
HFD1_k127_6585966_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001207 283.0
HFD1_k127_6585966_2 PFAM RDD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000002032 199.0
HFD1_k127_6585966_3 thiolester hydrolase activity K17362 - - 0.000000000000000000000000000000002046 136.0
HFD1_k127_6585966_4 FAD dependent oxidoreductase - - - 0.00000000000000000005198 90.0
HFD1_k127_6587727_0 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 545.0
HFD1_k127_6587727_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 372.0
HFD1_k127_6587727_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000006938 56.0
HFD1_k127_6590078_0 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 334.0
HFD1_k127_6590078_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 312.0
HFD1_k127_6590078_2 - - - - 0.00000000000000000000000000006855 123.0
HFD1_k127_6590078_3 Glutathione peroxidase K00432 - 1.11.1.9 0.00000001153 59.0
HFD1_k127_6590876_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 596.0
HFD1_k127_6590876_1 permease K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 291.0
HFD1_k127_6590876_2 EamA-like transporter family - - - 0.00000006605 54.0
HFD1_k127_6601005_0 ribonuclease E activity K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003356 262.0
HFD1_k127_6601005_1 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000001745 216.0
HFD1_k127_6606503_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 432.0
HFD1_k127_6606503_1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 363.0
HFD1_k127_6643420_0 DEAD DEAH box helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 539.0
HFD1_k127_6648946_0 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 569.0
HFD1_k127_6648946_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 428.0
HFD1_k127_6655769_0 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 343.0
HFD1_k127_6655769_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 347.0
HFD1_k127_6666206_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.093e-251 786.0
HFD1_k127_6666206_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 526.0
HFD1_k127_6666206_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000003242 140.0
HFD1_k127_6666206_3 PFAM NHL repeat containing protein - - - 0.000000000000000000000000001342 125.0
HFD1_k127_6666206_4 Sporulation related domain K03749 - - 0.00000000000000000000007856 107.0
HFD1_k127_6666206_5 Colicin v production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.000000000000000002459 93.0
HFD1_k127_6669777_0 helicase K03722 - 3.6.4.12 8.11e-200 642.0
HFD1_k127_6669777_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001909 267.0
HFD1_k127_6669777_2 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000005497 240.0
HFD1_k127_6669777_3 Protein of unknown function (DUF465) - - - 0.0000000000003 78.0
HFD1_k127_6670998_0 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 4.933e-207 648.0
HFD1_k127_6670998_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 525.0
HFD1_k127_6670998_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 337.0
HFD1_k127_6670998_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 287.0
HFD1_k127_6670998_4 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0004217 42.0
HFD1_k127_6678311_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 516.0
HFD1_k127_6678311_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 386.0
HFD1_k127_6678311_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 358.0
HFD1_k127_6678311_3 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000003776 213.0
HFD1_k127_6678311_4 - - - - 0.0000000000000000000000000000000000000000000000000002599 194.0
HFD1_k127_6678311_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000003905 179.0
HFD1_k127_6678311_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000002045 145.0
HFD1_k127_6685986_0 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001073 301.0
HFD1_k127_6685986_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005406 253.0
HFD1_k127_6685986_2 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000606 223.0
HFD1_k127_6687236_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 436.0
HFD1_k127_6687236_1 Belongs to the FPP GGPP synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 379.0
HFD1_k127_6687236_3 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 288.0
HFD1_k127_6687236_4 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000089 273.0
HFD1_k127_6687236_6 - - - - 0.00000000000000000000001486 106.0
HFD1_k127_6723161_0 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 607.0
HFD1_k127_6723161_1 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 391.0
HFD1_k127_6723161_2 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 289.0
HFD1_k127_6723161_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000007079 239.0
HFD1_k127_6723161_4 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000005998 196.0
HFD1_k127_6724389_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 313.0
HFD1_k127_6724389_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000002203 119.0
HFD1_k127_6740438_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.056e-281 874.0
HFD1_k127_6740438_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 302.0
HFD1_k127_6740438_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000006951 56.0
HFD1_k127_6740438_3 Transglycosylase SLT domain - - - 0.0005459 48.0
HFD1_k127_6740598_0 ATPases associated with a variety of cellular activities K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 490.0
HFD1_k127_6740598_1 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 468.0
HFD1_k127_6740598_10 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000004457 54.0
HFD1_k127_6740598_2 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 453.0
HFD1_k127_6740598_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 342.0
HFD1_k127_6740598_4 Biopolymer transport K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001718 274.0
HFD1_k127_6740598_5 Periplasmic binding protein K02016,K06858 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004807 274.0
HFD1_k127_6740598_6 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000004407 220.0
HFD1_k127_6740598_7 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000003005 195.0
HFD1_k127_6740598_8 Biopolymer transport protein, ExbD K03559 - - 0.00000000000000000000000000000000000533 151.0
HFD1_k127_6740598_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000008455 133.0
HFD1_k127_6745984_0 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 332.0
HFD1_k127_6745984_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000004377 149.0
HFD1_k127_6749662_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 578.0
HFD1_k127_6749662_1 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000008483 218.0
HFD1_k127_6749662_2 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000001331 188.0
HFD1_k127_6757209_0 Belongs to the malic enzymes family K00029 - 1.1.1.40 3.757e-265 829.0
HFD1_k127_6757209_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
HFD1_k127_6757209_2 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000001937 151.0
HFD1_k127_6757209_3 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000000004869 119.0
HFD1_k127_6775162_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 538.0
HFD1_k127_6775162_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 256.0
HFD1_k127_6775162_2 Belongs to the frataxin family K06202 - - 0.000000000000000000000000000000003096 131.0
HFD1_k127_6775162_3 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000003169 124.0
HFD1_k127_6785124_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 512.0
HFD1_k127_6785124_1 PFAM CHAD domain containing protein K01768 - 4.6.1.1 0.0000000000000000000000005788 113.0
HFD1_k127_6785124_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000003679 86.0
HFD1_k127_6787694_0 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001086 270.0
HFD1_k127_6787694_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000001186 218.0
HFD1_k127_6794670_0 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 601.0
HFD1_k127_6794670_1 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 421.0
HFD1_k127_6794670_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003872 230.0
HFD1_k127_6794670_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000001017 141.0
HFD1_k127_6794670_4 Protein of unknown function (DUF3297) - - - 0.0000000000000000000000000000000001337 137.0
HFD1_k127_6794670_5 Type II secretion system protein B - - - 0.000000000000000000000000000003962 131.0
HFD1_k127_6794670_6 ribonuclease BN - - - 0.00000000000004535 79.0
HFD1_k127_6794670_7 extracellular matrix structural constituent - - - 0.000000007245 63.0
HFD1_k127_6794788_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000972 282.0
HFD1_k127_6794788_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008007 252.0
HFD1_k127_6794788_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000009007 188.0
HFD1_k127_6794788_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000004552 126.0
HFD1_k127_6794918_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 284.0
HFD1_k127_6794918_1 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001569 255.0
HFD1_k127_6798526_0 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 469.0
HFD1_k127_6798526_1 Threonyl alanyl tRNA synthetase K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 332.0
HFD1_k127_6798526_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 300.0
HFD1_k127_6798526_3 acyl-coA-binding protein - - - 0.000000000000000000000000000001248 123.0
HFD1_k127_6802491_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.039e-280 866.0
HFD1_k127_6802491_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.308e-277 857.0
HFD1_k127_6802491_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000007517 181.0
HFD1_k127_6802491_11 FR47-like protein - - - 0.00000000000000000000000000000000000000000000004286 186.0
HFD1_k127_6802491_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000009963 142.0
HFD1_k127_6802491_13 PFAM Cytochrome C K17230 - - 0.000000000000000000000000000003017 124.0
HFD1_k127_6802491_14 ATP synthase I chain K02116 - - 0.000000000000000000000000006782 114.0
HFD1_k127_6802491_15 Universal stress protein - - - 0.00000000000000000000000001202 117.0
HFD1_k127_6802491_2 Glucose / Sorbosone dehydrogenase - - - 1.306e-239 744.0
HFD1_k127_6802491_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 413.0
HFD1_k127_6802491_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 354.0
HFD1_k127_6802491_5 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 346.0
HFD1_k127_6802491_6 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 285.0
HFD1_k127_6802491_7 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001198 251.0
HFD1_k127_6802491_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000001828 190.0
HFD1_k127_6802491_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000002985 186.0
HFD1_k127_6811856_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000023 194.0
HFD1_k127_6815880_0 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 424.0
HFD1_k127_6815880_1 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 391.0
HFD1_k127_6823733_0 surface antigen (D15) K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 439.0
HFD1_k127_6823733_1 protein conserved in bacteria K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 454.0
HFD1_k127_6823733_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002623 272.0
HFD1_k127_6873220_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.00000000000000000000000000000000000000407 145.0
HFD1_k127_6873220_1 - - - - 0.000000000000000000000000000000007541 133.0
HFD1_k127_6879743_0 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000075 252.0
HFD1_k127_6879743_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000003408 194.0
HFD1_k127_6879743_2 Histidine kinase - - - 0.00000000000000000000598 107.0
HFD1_k127_6879743_3 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000003638 89.0
HFD1_k127_6880521_0 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 352.0
HFD1_k127_6880521_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000006915 162.0
HFD1_k127_6902744_0 - - - - 0.000000000000000000000000000000000000000000000000000000004289 208.0
HFD1_k127_6902744_1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000005251 133.0
HFD1_k127_6909884_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 302.0
HFD1_k127_6909884_1 Flagellar protein FliT K02423 - - 0.00000000000006003 79.0
HFD1_k127_6909884_2 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000000002399 79.0
HFD1_k127_6914603_0 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 589.0
HFD1_k127_6914603_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 415.0
HFD1_k127_6920204_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 6.222e-228 709.0
HFD1_k127_6920204_1 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 535.0
HFD1_k127_6920204_2 Cytochrome oxidase maturation protein - - - 0.0006751 53.0
HFD1_k127_6958162_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 342.0
HFD1_k127_6958162_1 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 332.0
HFD1_k127_6958162_2 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 296.0
HFD1_k127_6958162_3 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005972 272.0
HFD1_k127_6958162_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000001397 184.0
HFD1_k127_6974255_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 563.0
HFD1_k127_6974255_1 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000007542 251.0
HFD1_k127_6974255_2 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
HFD1_k127_6974255_3 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000000883 180.0
HFD1_k127_6974255_4 Protein of unknown function (DUF3579) - - - 0.0000000000000000000000000000000000004415 151.0
HFD1_k127_6974255_5 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000005865 110.0
HFD1_k127_6976407_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 351.0
HFD1_k127_6976407_1 Nad-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000207 241.0
HFD1_k127_6976407_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000001919 237.0
HFD1_k127_6976407_3 acetyltransferase - - - 0.000000000000000000000000000000000000001318 151.0
HFD1_k127_6976407_4 Protein of unknown function (DUF2905) - - - 0.00000000000000001493 84.0
HFD1_k127_7022033_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 596.0
HFD1_k127_7022033_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000355 51.0
HFD1_k127_7130493_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 589.0
HFD1_k127_7130493_1 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 347.0
HFD1_k127_7130493_2 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000006385 128.0
HFD1_k127_7130493_3 DNA polymerase III (Chi subunit) K02339 - 2.7.7.7 0.000000000267 62.0
HFD1_k127_7149352_0 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 409.0
HFD1_k127_7149352_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000001339 160.0
HFD1_k127_7177578_0 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 461.0
HFD1_k127_7177578_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000001453 105.0
HFD1_k127_7197273_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 560.0
HFD1_k127_7197273_1 LexA DNA binding domain - - - 0.0000000000000000000000000000000000001187 143.0
HFD1_k127_7197273_2 DDE superfamily endonuclease - - - 0.000000000000000005032 87.0
HFD1_k127_7232706_0 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000006616 217.0
HFD1_k127_7232706_1 PFAM chitin-binding domain 3 protein - - - 0.0000000000000001149 87.0
HFD1_k127_7235621_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 9.244e-256 800.0
HFD1_k127_7235621_1 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 383.0
HFD1_k127_7235621_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000003098 261.0
HFD1_k127_7240038_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 436.0
HFD1_k127_7240038_1 Periplasmic protein thiol disulfide oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000002442 243.0
HFD1_k127_7240038_2 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000001987 161.0
HFD1_k127_7240038_3 COG4235 Cytochrome c biogenesis factor K02200 - - 0.00000000000000000000005056 107.0
HFD1_k127_7245848_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1725.0
HFD1_k127_7245848_1 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003701 265.0
HFD1_k127_7253952_0 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 379.0
HFD1_k127_7253952_1 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 334.0
HFD1_k127_7253952_2 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000000000000000004511 162.0
HFD1_k127_7262297_0 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 599.0
HFD1_k127_7262297_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 403.0
HFD1_k127_7262297_2 Peptidase family M3 K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 371.0
HFD1_k127_7262297_3 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 316.0
HFD1_k127_7262297_4 helix_turn_helix, Lux Regulon K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005961 288.0
HFD1_k127_7275520_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 1.204e-219 702.0
HFD1_k127_7275520_1 Histidine kinase K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 482.0
HFD1_k127_7280108_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 369.0
HFD1_k127_7280108_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003296 255.0
HFD1_k127_7291783_0 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000002942 229.0
HFD1_k127_7291783_1 VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000006422 186.0
HFD1_k127_7291783_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000002838 117.0
HFD1_k127_7291783_3 STAS domain K07122 - - 0.000000000009106 69.0
HFD1_k127_7299041_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 590.0
HFD1_k127_7299041_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000001513 247.0
HFD1_k127_7299041_2 Glutaredoxin - - - 0.000000004369 67.0
HFD1_k127_7299139_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 533.0
HFD1_k127_7299139_1 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000002034 138.0
HFD1_k127_7299139_2 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000007073 80.0
HFD1_k127_7301164_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 458.0
HFD1_k127_7301164_1 mRNA binding - - - 0.000003899 48.0
HFD1_k127_7301164_2 PFAM YcfA-like protein - - - 0.00004279 51.0
HFD1_k127_7306553_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 4.266e-261 805.0
HFD1_k127_7306553_1 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000002622 231.0
HFD1_k127_7306553_2 RecG wedge domain K03655 - 3.6.4.12 0.00000000000000000000000000004183 116.0
HFD1_k127_7311330_0 Cyclohexanecarboxylate-CoA ligase K04116,K12507 - - 4.782e-226 711.0
HFD1_k127_7311330_1 PFAM amidohydrolase 2 K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 489.0
HFD1_k127_7311330_2 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 372.0
HFD1_k127_7311330_3 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000007668 230.0
HFD1_k127_7311330_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000003286 95.0
HFD1_k127_7311330_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000005577 54.0
HFD1_k127_7313936_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 420.0
HFD1_k127_7313936_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004201 275.0
HFD1_k127_7318249_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 7.557e-199 624.0
HFD1_k127_7318249_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 581.0
HFD1_k127_7318249_2 LysM domain K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 430.0
HFD1_k127_7318249_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 357.0
HFD1_k127_7318249_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000703 225.0
HFD1_k127_7319356_0 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 385.0
HFD1_k127_7319356_1 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000174 113.0
HFD1_k127_7319356_2 ABC transporter K01990 - - 0.00000004045 55.0
HFD1_k127_7319356_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000005543 51.0
HFD1_k127_7319764_0 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000003257 233.0
HFD1_k127_7319764_1 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000301 192.0
HFD1_k127_7319764_2 Ribonuclease E/G family K08301 - - 0.0000003592 53.0
HFD1_k127_7320290_0 LUD domain K18929 - - 1.369e-194 613.0
HFD1_k127_7320290_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 413.0
HFD1_k127_7320290_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 389.0
HFD1_k127_7320290_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001436 276.0
HFD1_k127_7320290_4 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004095 273.0
HFD1_k127_7320290_5 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000003082 139.0
HFD1_k127_7320290_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0008452,GO:0008664,GO:0016787,GO:0016788,GO:0016874,GO:0016886,GO:0042578,GO:0140098 3.1.4.58 0.0000000000000000001736 94.0
HFD1_k127_7329773_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 513.0
HFD1_k127_7329773_1 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008327 251.0
HFD1_k127_7329773_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000003636 151.0
HFD1_k127_7330985_0 LUD domain K18929 - - 2.752e-213 670.0
HFD1_k127_7330985_1 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 406.0
HFD1_k127_7330985_2 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 380.0
HFD1_k127_7334837_0 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005667 293.0
HFD1_k127_7339074_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1140.0
HFD1_k127_7339074_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 8.871e-313 996.0
HFD1_k127_7339074_2 amidohydrolase K01451 - 3.5.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 558.0
HFD1_k127_7339074_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 537.0
HFD1_k127_7339074_4 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 519.0
HFD1_k127_7339074_5 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 443.0
HFD1_k127_7339074_6 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 361.0
HFD1_k127_7339074_7 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005005 280.0
HFD1_k127_7339074_8 - - - - 0.00000000000007724 79.0
HFD1_k127_7339074_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00005114 50.0
HFD1_k127_7348647_0 Belongs to the GMC oxidoreductase family - - - 2.106e-194 621.0
HFD1_k127_7348647_1 Pfam Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 382.0
HFD1_k127_7348647_2 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000001881 138.0
HFD1_k127_7348647_3 Protein of unknown function (DUF3567) - - - 0.00000000000000000000026 100.0
HFD1_k127_7348836_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 578.0
HFD1_k127_7348836_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000177 259.0
HFD1_k127_7348836_2 PEP-CTERM motif - - - 0.000000000000000000000000000008172 124.0
HFD1_k127_7348836_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000003424 104.0
HFD1_k127_7357077_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 407.0
HFD1_k127_7357077_1 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000005295 131.0
HFD1_k127_7357077_2 Protein of unknown function (DUF2788) - - - 0.0000000000000000000352 98.0
HFD1_k127_7366023_0 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 2.785e-311 965.0
HFD1_k127_7366023_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 371.0
HFD1_k127_7366023_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000001931 145.0
HFD1_k127_7366023_3 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000001294 119.0
HFD1_k127_7372194_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.534e-281 874.0
HFD1_k127_7372194_1 TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 468.0
HFD1_k127_7372194_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000002227 106.0
HFD1_k127_7372194_3 - - - - 0.0000006825 53.0
HFD1_k127_7374554_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001848 255.0
HFD1_k127_7374554_1 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000005089 198.0
HFD1_k127_7383290_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1438.0
HFD1_k127_7383290_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.803e-251 792.0
HFD1_k127_7383290_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 456.0
HFD1_k127_7383290_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 430.0
HFD1_k127_7383290_4 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 441.0
HFD1_k127_7383290_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000001031 216.0
HFD1_k127_7383290_6 response regulator receiver K13041 - - 0.0000000000000000000000000000000000000000000000000562 185.0
HFD1_k127_7383290_7 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000002605 190.0
HFD1_k127_7383290_8 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000003024 175.0
HFD1_k127_7383290_9 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000005934 156.0
HFD1_k127_7384979_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 363.0
HFD1_k127_7392445_0 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 304.0
HFD1_k127_7392445_1 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000003841 134.0
HFD1_k127_7392445_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000008324 79.0
HFD1_k127_7399468_0 FtsX-like permease family K02004 - - 8.065e-280 885.0
HFD1_k127_7399468_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 475.0
HFD1_k127_7409007_0 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1254.0
HFD1_k127_7409007_1 membrane - - - 0.0000000000000000000000000009016 113.0
HFD1_k127_7412514_0 D-amino acid K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 507.0
HFD1_k127_7412514_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 481.0
HFD1_k127_7412514_10 - - - - 0.000000000000000001991 93.0
HFD1_k127_7412514_11 - - - - 0.0000000000005019 72.0
HFD1_k127_7412514_12 Transcriptional regulator K07734 - - 0.000000002223 60.0
HFD1_k127_7412514_13 - - - - 0.000000004025 60.0
HFD1_k127_7412514_2 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 476.0
HFD1_k127_7412514_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 432.0
HFD1_k127_7412514_4 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 396.0
HFD1_k127_7412514_5 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 400.0
HFD1_k127_7412514_6 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
HFD1_k127_7412514_7 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 310.0
HFD1_k127_7412514_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000002252 176.0
HFD1_k127_7412514_9 Cytochrome K08738 - - 0.00000000000000000000000000000000004438 137.0
HFD1_k127_7419619_0 Transposase and inactivated - - - 0.00000000000000000000000000000000000000000000000000000000000000000002489 241.0
HFD1_k127_7419619_1 Transposase - - - 0.00000000000000000000000000000002652 132.0
HFD1_k127_7419619_2 Transposase - - - 0.0000000000000000002424 91.0
HFD1_k127_7419619_3 DDE superfamily endonuclease - - - 0.0000000002944 65.0
HFD1_k127_7419619_4 Transposase K07494 - - 0.000001164 53.0
HFD1_k127_7420737_0 PFAM Glycoside hydrolase 15-related - - - 4.647e-229 724.0
HFD1_k127_7420737_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 1.865e-206 654.0
HFD1_k127_7420737_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000001659 171.0
HFD1_k127_7420737_3 Belongs to the peptidase S8 family - - - 0.000000001414 66.0
HFD1_k127_7435670_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 497.0
HFD1_k127_7435670_1 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000689 112.0
HFD1_k127_7435670_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000003452 111.0
HFD1_k127_7444879_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 528.0
HFD1_k127_7444879_1 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 436.0
HFD1_k127_7447025_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 565.0
HFD1_k127_7447025_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 531.0
HFD1_k127_7447025_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001744 278.0
HFD1_k127_7447025_4 Protein of unknown function (DUF3455) - - - 0.00000000000000000007275 98.0
HFD1_k127_7461635_0 Histidine kinase K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 610.0
HFD1_k127_7464062_0 Transport of potassium into the cell K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 388.0
HFD1_k127_7465020_0 KR domain K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 293.0
HFD1_k127_7465020_1 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000002217 199.0
HFD1_k127_7465020_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001179 165.0
HFD1_k127_7473656_0 to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 419.0
HFD1_k127_7473656_1 Class II aldolase K01628,K22130 - 4.1.1.104,4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 377.0
HFD1_k127_7473656_2 PFAM type III effector Hrp-dependent outers K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 276.0
HFD1_k127_7473656_3 Male sterility protein K22025 - 1.1.1.410 0.00000000000000000000000000000002042 128.0
HFD1_k127_7525302_0 PQQ enzyme repeat - - - 1.979e-295 915.0
HFD1_k127_7525302_1 Ankyrin repeats (3 copies) K06867,K21440 - - 0.00000000000000000000000000000000000000000000001586 179.0
HFD1_k127_7525302_2 Cytochrome b/b6/petB - - - 0.00000000000000000000000000000000000000000002866 171.0
HFD1_k127_7525302_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000001149 112.0
HFD1_k127_7525302_4 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000001883 82.0
HFD1_k127_7548986_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1573.0
HFD1_k127_7548986_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000001351 86.0
HFD1_k127_7552870_0 Pilus retraction K02669,K12203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 597.0
HFD1_k127_7552870_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 324.0
HFD1_k127_7552870_2 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000296 181.0
HFD1_k127_7557618_0 His Kinase A (phosphoacceptor) domain K02484,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 327.0
HFD1_k127_7557618_1 PFAM Response regulator receiver domain, Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000002007 211.0
HFD1_k127_7561206_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 508.0
HFD1_k127_7561206_1 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000005558 237.0
HFD1_k127_7561206_2 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000007919 229.0
HFD1_k127_7561206_3 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000001659 236.0
HFD1_k127_7561206_4 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000002742 151.0
HFD1_k127_7561206_5 PFAM Di-haem cytochrome c - - - 0.0000000000000000000000000000000000003666 145.0
HFD1_k127_7561206_6 mechanosensitive ion channel - - - 0.00000000000000000000000002361 111.0
HFD1_k127_7572270_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 8.66e-321 1016.0
HFD1_k127_7572270_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.92e-246 772.0
HFD1_k127_7572270_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 538.0
HFD1_k127_7572270_3 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 377.0
HFD1_k127_7572270_4 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000000001102 214.0
HFD1_k127_7572270_5 Cobalt uptake substrate-specific transmembrane region - - - 0.000000000000000000000007595 110.0
HFD1_k127_7572270_6 - - - - 0.00000000000000077 80.0
HFD1_k127_7601629_0 PFAM EAL domain, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000008557 203.0
HFD1_k127_7601629_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000171 82.0
HFD1_k127_7604605_0 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004638 273.0
HFD1_k127_7604605_1 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005923 253.0
HFD1_k127_7604605_2 nucleotidyltransferase activity - - - 0.000000000000000000006396 102.0
HFD1_k127_7604605_3 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000001285 59.0
HFD1_k127_7619962_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 492.0
HFD1_k127_7619962_1 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 472.0
HFD1_k127_7619962_2 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 295.0
HFD1_k127_7624798_0 COG3335 Transposase and inactivated derivatives K07494 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 480.0
HFD1_k127_7624798_1 Transposase K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 421.0
HFD1_k127_7624798_2 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.000000000000000002258 90.0
HFD1_k127_7654310_0 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 343.0
HFD1_k127_7654310_1 branched-chain amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000002992 203.0
HFD1_k127_7654310_2 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000004148 57.0
HFD1_k127_7668526_0 lipase activity - - - 0.000000000000000000000000000000000000000000000000000001366 205.0
HFD1_k127_7668526_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000001955 146.0
HFD1_k127_7668526_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000001747 102.0
HFD1_k127_7681709_0 dihydroxyacetone kinase K00863,K05878 - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 546.0
HFD1_k127_7681709_1 PFAM Transketolase central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 533.0
HFD1_k127_7681709_2 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 469.0
HFD1_k127_7681709_3 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 416.0
HFD1_k127_7681709_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 413.0
HFD1_k127_7681709_5 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 376.0
HFD1_k127_7681709_6 Dak1 domain K00863,K05878 - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 287.0
HFD1_k127_7681709_7 LysR family K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000708 282.0
HFD1_k127_7681709_8 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000001766 244.0
HFD1_k127_7681709_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00002795 50.0
HFD1_k127_7691396_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 499.0
HFD1_k127_7691396_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 473.0
HFD1_k127_7691396_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 461.0
HFD1_k127_7691396_3 - K07112 - - 0.0000000000000000000000000000000000000000002787 166.0
HFD1_k127_7691396_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000005939 164.0
HFD1_k127_7691396_5 response regulator, receiver K03413 - - 0.00000000000000000000000000000000002346 141.0
HFD1_k127_7691396_6 Flagellar protein YcgR - - - 0.00000000000007921 83.0
HFD1_k127_7691396_7 - - - - 0.0000003824 52.0
HFD1_k127_7696781_0 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 394.0
HFD1_k127_7696781_1 N-carbamoyl-D-amino acid hydrolase K01459 - 3.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000005873 261.0
HFD1_k127_7696781_2 Sensors of blue-light using FAD - - - 0.00000000000000000000000000000000000000000000000000000000004463 220.0
HFD1_k127_7696781_3 Nuclease (SNase domain protein) - - - 0.0000000000000000000000000000000000000000000000002835 181.0
HFD1_k127_7696781_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000001134 99.0
HFD1_k127_7697164_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1127.0
HFD1_k127_7721408_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.328e-275 851.0
HFD1_k127_7721408_1 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 483.0
HFD1_k127_7721408_2 ArgK protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 311.0
HFD1_k127_7721408_3 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.0000000000000000000000000000001496 124.0
HFD1_k127_7723593_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 1.549e-226 715.0
HFD1_k127_7723593_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 370.0
HFD1_k127_7723593_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 310.0
HFD1_k127_7723593_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001974 237.0
HFD1_k127_7723593_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000002279 226.0
HFD1_k127_7723593_5 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.000000006119 60.0
HFD1_k127_7812690_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 507.0
HFD1_k127_7812690_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000002704 195.0
HFD1_k127_7813187_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 533.0
HFD1_k127_7813187_1 carboxylase K01969 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 520.0
HFD1_k127_7898004_0 Transport of potassium into the cell K03549 - - 1.168e-222 711.0
HFD1_k127_7898004_1 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 477.0
HFD1_k127_7898004_2 Regulator K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 309.0
HFD1_k127_7898004_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 294.0
HFD1_k127_7898004_4 Protein of unknown function (DUF1615) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.00000000000002566 80.0
HFD1_k127_7925978_0 elongation factor G K02355 - - 5.383e-239 749.0
HFD1_k127_7925978_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 347.0
HFD1_k127_7925978_2 - - - - 0.000000000000002723 84.0
HFD1_k127_7976350_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 3.452e-295 942.0
HFD1_k127_7976350_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 599.0
HFD1_k127_7976350_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000544 211.0
HFD1_k127_7976455_0 Transcriptional regulator K03566 - - 0.00000000001505 67.0
HFD1_k127_7976455_1 PEP-CTERM motif - - - 0.000002143 59.0
HFD1_k127_797760_0 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 458.0
HFD1_k127_797760_1 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 397.0
HFD1_k127_797760_2 - - - - 0.0000000000000000000000006156 107.0
HFD1_k127_797760_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000004758 83.0
HFD1_k127_797760_4 InterPro IPR007367 - - - 0.0000001749 55.0
HFD1_k127_804243_0 PFAM transposase mutator type - - - 5.326e-200 629.0
HFD1_k127_804243_1 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000000000000003702 93.0
HFD1_k127_807147_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 2.607e-239 756.0
HFD1_k127_807147_1 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002107 243.0
HFD1_k127_807584_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 422.0
HFD1_k127_807584_1 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 364.0
HFD1_k127_807584_2 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 340.0
HFD1_k127_807584_3 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 323.0
HFD1_k127_807584_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001261 276.0
HFD1_k127_807584_5 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000000144 200.0
HFD1_k127_810052_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.435e-250 782.0
HFD1_k127_810052_1 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 421.0
HFD1_k127_810052_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 311.0
HFD1_k127_810052_3 Belongs to the ComB family K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000000000000005379 206.0
HFD1_k127_810052_4 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000001671 168.0
HFD1_k127_810052_5 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000001072 94.0
HFD1_k127_810052_6 electron transfer activity K03737,K05337 - 1.2.7.1 0.0003182 54.0
HFD1_k127_813845_0 Superoxide dismutase K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 449.0
HFD1_k127_813845_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003863 281.0
HFD1_k127_813845_2 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003039 273.0
HFD1_k127_819308_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1400.0
HFD1_k127_819308_1 PFAM PrkA AAA K07180 - - 2.73e-301 938.0
HFD1_k127_819308_2 SpoVR like protein K06415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 590.0
HFD1_k127_819308_3 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 490.0
HFD1_k127_819308_4 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 411.0
HFD1_k127_819308_5 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 390.0
HFD1_k127_819308_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000003159 164.0
HFD1_k127_819308_7 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000835 50.0
HFD1_k127_819712_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 533.0
HFD1_k127_819712_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000003192 182.0
HFD1_k127_819712_2 - - - - 0.00000000000000000000000000000000002832 136.0
HFD1_k127_820849_0 Isocitrate lyase K01637 - 4.1.3.1 9.801e-251 779.0
HFD1_k127_820849_1 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000329 215.0
HFD1_k127_820858_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004991 278.0
HFD1_k127_820858_1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000005681 95.0
HFD1_k127_824911_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 480.0
HFD1_k127_824911_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 447.0
HFD1_k127_824911_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 338.0
HFD1_k127_824911_3 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000003562 185.0
HFD1_k127_824911_4 cellulase activity - - - 0.00000000000000000000000006324 124.0
HFD1_k127_827111_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 521.0
HFD1_k127_827111_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 462.0
HFD1_k127_827111_2 PFAM L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 385.0
HFD1_k127_827111_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 305.0
HFD1_k127_827111_4 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000000000005366 210.0
HFD1_k127_827111_5 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000302 192.0
HFD1_k127_827111_6 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000000000000009408 184.0
HFD1_k127_827111_7 DNA polymerase K02347 - - 0.00000000000000000000000000000001295 130.0
HFD1_k127_827111_8 MFS/sugar transport protein - - - 0.0000000000000000000000000000001079 126.0
HFD1_k127_827111_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000001423 129.0
HFD1_k127_832153_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 585.0
HFD1_k127_832153_1 Small Multidrug Resistance protein - - - 0.000000000000000000000000000000000000000000000001407 177.0
HFD1_k127_832153_2 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.0000000000000000000000005619 113.0
HFD1_k127_834491_0 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 337.0
HFD1_k127_834491_1 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 332.0
HFD1_k127_834491_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001988 280.0
HFD1_k127_834491_3 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001947 245.0
HFD1_k127_834491_4 SMART cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000001458 206.0
HFD1_k127_834491_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000008889 94.0
HFD1_k127_834491_6 ABC transporter K02013 - 3.6.3.34 0.00000000002569 75.0
HFD1_k127_834491_7 - - - - 0.0002373 50.0
HFD1_k127_837346_0 ANTAR K22010 - - 0.0000000000000000000000000000000000000000000000003533 183.0
HFD1_k127_837346_1 - - - - 0.00000000000000001381 88.0
HFD1_k127_838700_0 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 363.0
HFD1_k127_838700_1 rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000001312 164.0
HFD1_k127_838700_2 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000001656 153.0
HFD1_k127_842614_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 501.0
HFD1_k127_842614_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 470.0
HFD1_k127_842614_10 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000000199 126.0
HFD1_k127_842614_11 Ribosomal L28 family K02902 - - 0.0000000000000000000003453 110.0
HFD1_k127_842614_2 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 466.0
HFD1_k127_842614_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 408.0
HFD1_k127_842614_4 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 301.0
HFD1_k127_842614_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001239 270.0
HFD1_k127_842614_6 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001337 264.0
HFD1_k127_842614_7 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000003259 183.0
HFD1_k127_842614_8 COG0350 Methylated DNA-protein cysteine methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000191 172.0
HFD1_k127_842614_9 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000004742 162.0
HFD1_k127_846719_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.738e-197 623.0
HFD1_k127_850111_0 semialdehyde reductase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 366.0
HFD1_k127_850111_1 esterase K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 311.0
HFD1_k127_850111_2 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000001256 78.0
HFD1_k127_850111_3 Chorismate mutase K00014,K00891,K04092,K04516 - 1.1.1.25,2.7.1.71,5.4.99.5 0.000002774 52.0
HFD1_k127_850903_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 409.0
HFD1_k127_850903_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001455 276.0
HFD1_k127_850903_2 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006086 245.0
HFD1_k127_850903_3 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000004817 220.0
HFD1_k127_850906_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 614.0
HFD1_k127_852795_0 COG1840 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 495.0
HFD1_k127_852795_1 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 373.0
HFD1_k127_852795_2 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 362.0
HFD1_k127_852795_3 Belongs to the ABC transporter superfamily K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 332.0
HFD1_k127_855680_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 313.0
HFD1_k127_855680_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004535 274.0
HFD1_k127_855680_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008556 244.0
HFD1_k127_855680_3 acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000008614 137.0
HFD1_k127_857339_0 Carboxypeptidase regulatory-like domain - - - 1.168e-299 930.0
HFD1_k127_857339_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000002809 101.0
HFD1_k127_859107_0 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 481.0
HFD1_k127_859107_1 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 329.0
HFD1_k127_859107_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000005669 117.0
HFD1_k127_860516_0 Penicillin amidase K01434 - 3.5.1.11 5.088e-238 768.0
HFD1_k127_860516_1 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 345.0
HFD1_k127_860516_2 NAD(P)H-binding - - - 0.00000007699 56.0
HFD1_k127_869429_0 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 7.104e-197 619.0
HFD1_k127_869429_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004243 274.0
HFD1_k127_869429_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000008089 179.0
HFD1_k127_869429_3 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000000000000000000000000000166 162.0
HFD1_k127_869429_4 MAPEG family - - - 0.000000000000000000000000000000000001661 143.0
HFD1_k127_869429_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00002557 46.0
HFD1_k127_870290_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 541.0
HFD1_k127_870290_1 Zn-dependent protease with chaperone function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
HFD1_k127_870290_2 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 293.0
HFD1_k127_870290_3 intradiol ring-cleavage dioxygenase - - - 0.000003691 51.0
HFD1_k127_871384_0 ABC-type Fe3 transport system permease component K02011 - - 5.276e-255 799.0
HFD1_k127_871384_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.045e-221 695.0
HFD1_k127_871384_10 Glutathione S-transferase, N-terminal domain K11208 - - 0.00000000000000000000000000000000004452 152.0
HFD1_k127_871384_11 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000224 138.0
HFD1_k127_871384_12 Outer membrane protein beta-barrel domain - - - 0.000000000000000442 91.0
HFD1_k127_871384_2 Belongs to the thiolase family K00626 - 2.3.1.9 6.438e-198 625.0
HFD1_k127_871384_3 ABC-type Fe3 transport system, periplasmic component - - - 1.632e-197 624.0
HFD1_k127_871384_4 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 471.0
HFD1_k127_871384_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008188 286.0
HFD1_k127_871384_6 Phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001897 282.0
HFD1_k127_871384_7 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006462 275.0
HFD1_k127_871384_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001272 250.0
HFD1_k127_871384_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000003288 189.0
HFD1_k127_879448_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 427.0
HFD1_k127_879448_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000006034 251.0
HFD1_k127_879448_2 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000008339 149.0
HFD1_k127_880057_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 543.0
HFD1_k127_880057_1 Ferredoxin K04755 - - 0.000000000000000000000000000000000000000000000003315 176.0
HFD1_k127_883136_0 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 597.0
HFD1_k127_883136_1 - - - - 0.000000000000000000000000000000000000004599 160.0
HFD1_k127_883136_2 membrane - - - 0.000000000000000000000000000000607 128.0
HFD1_k127_883136_3 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000001715 83.0
HFD1_k127_883136_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000008339 49.0
HFD1_k127_883622_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.816e-309 963.0
HFD1_k127_883622_1 Belongs to the ClpA ClpB family K03694 - - 2.19e-254 790.0
HFD1_k127_883622_10 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000797 173.0
HFD1_k127_883622_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000005943 158.0
HFD1_k127_883622_12 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000001604 149.0
HFD1_k127_883622_13 Cold shock protein K03704 - - 0.00000000000000000000000000000000001372 139.0
HFD1_k127_883622_14 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000001492 129.0
HFD1_k127_883622_15 Belongs to the UPF0434 family K09791 - - 0.00000000000000000001839 92.0
HFD1_k127_883622_2 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 7.6e-239 743.0
HFD1_k127_883622_3 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.137e-203 652.0
HFD1_k127_883622_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 414.0
HFD1_k127_883622_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 371.0
HFD1_k127_883622_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 358.0
HFD1_k127_883622_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 332.0
HFD1_k127_883622_8 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 315.0
HFD1_k127_883622_9 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000004289 208.0
HFD1_k127_887854_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 447.0
HFD1_k127_887854_1 zinc protease protein - - - 0.00000000000000000000000000000000000000007202 155.0
HFD1_k127_904904_0 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000005481 216.0
HFD1_k127_904904_1 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000000000000000000000000000043 206.0
HFD1_k127_904904_2 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000002972 216.0
HFD1_k127_915772_0 FAD linked oxidase domain protein - - - 0.0 1652.0
HFD1_k127_915772_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 5.399e-241 755.0
HFD1_k127_915772_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 491.0
HFD1_k127_915772_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 449.0
HFD1_k127_915772_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 389.0
HFD1_k127_915772_5 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 319.0
HFD1_k127_915772_6 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000002264 189.0
HFD1_k127_915772_7 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000009803 183.0
HFD1_k127_915772_8 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000001675 150.0
HFD1_k127_915772_9 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000002691 119.0
HFD1_k127_923988_0 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 590.0
HFD1_k127_923988_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 512.0
HFD1_k127_923988_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 440.0
HFD1_k127_923988_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 315.0
HFD1_k127_923988_4 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000001673 221.0
HFD1_k127_923988_5 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000002831 209.0
HFD1_k127_923988_6 Membrane fusogenic activity K09806 - - 0.0000000000000000000265 93.0
HFD1_k127_933022_0 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 1.121e-220 708.0
HFD1_k127_933022_1 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 568.0
HFD1_k127_933022_2 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 471.0
HFD1_k127_933022_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 393.0
HFD1_k127_933022_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 348.0
HFD1_k127_933022_5 Regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001759 281.0
HFD1_k127_933022_6 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005032 258.0
HFD1_k127_933022_7 signal peptide protein - - - 0.00000000000000000000000000000000000000000000002647 178.0
HFD1_k127_933022_8 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000004045 114.0
HFD1_k127_935351_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.251e-235 737.0
HFD1_k127_935351_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 568.0
HFD1_k127_935351_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 421.0
HFD1_k127_935351_3 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 306.0
HFD1_k127_935351_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000006318 206.0
HFD1_k127_935351_5 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000002024 183.0
HFD1_k127_935351_6 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000004523 176.0
HFD1_k127_935351_7 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000004738 131.0
HFD1_k127_935351_8 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000001221 97.0
HFD1_k127_935351_9 Glutathione S-transferase K00799 - 2.5.1.18 0.00000002225 55.0
HFD1_k127_937573_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 358.0
HFD1_k127_937573_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009903 272.0
HFD1_k127_937573_2 malic enzyme K00029 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006090,GO:0006108,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0022607,GO:0032787,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.1.1.40 0.0000000000000002364 81.0
HFD1_k127_939266_0 acid transport system permease K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 388.0
HFD1_k127_939266_1 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 400.0
HFD1_k127_939266_2 (ABC) transporter K02028,K02029,K09972 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 376.0
HFD1_k127_946631_0 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 332.0
HFD1_k127_946631_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007321 262.0
HFD1_k127_946631_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000001398 129.0
HFD1_k127_946631_3 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000001804 113.0
HFD1_k127_949341_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.145e-313 974.0
HFD1_k127_949341_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 510.0
HFD1_k127_952741_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 305.0
HFD1_k127_952741_1 - - - - 0.00000000000000000000000000006744 124.0
HFD1_k127_954692_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 597.0
HFD1_k127_954692_1 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 347.0
HFD1_k127_954692_2 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000749 170.0
HFD1_k127_961875_0 Transposase, Mutator family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 572.0
HFD1_k127_961875_1 - - - - 0.000000001717 67.0
HFD1_k127_961875_2 transposase - - - 0.000000101 59.0
HFD1_k127_96299_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 521.0
HFD1_k127_96299_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 334.0
HFD1_k127_964948_0 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 379.0
HFD1_k127_964948_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000005312 214.0
HFD1_k127_964948_2 Erythromycin esterase - - - 0.0000000000000000000000000000000000000000000000000000005182 213.0
HFD1_k127_964948_3 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00003522 46.0
HFD1_k127_970878_0 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 1.101e-246 773.0
HFD1_k127_970878_1 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 565.0
HFD1_k127_970878_10 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.0007619 44.0
HFD1_k127_970878_2 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 472.0
HFD1_k127_970878_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 451.0
HFD1_k127_970878_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 402.0
HFD1_k127_970878_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 352.0
HFD1_k127_970878_6 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 320.0
HFD1_k127_970878_7 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000181 201.0
HFD1_k127_970878_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000953 158.0
HFD1_k127_970878_9 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000000000000000008864 134.0
HFD1_k127_971967_0 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002144 248.0
HFD1_k127_971967_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000001313 175.0
HFD1_k127_972790_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 604.0
HFD1_k127_972790_1 BON domain K04065 - - 0.000000000000000000000000001051 115.0
HFD1_k127_972790_2 ribonuclease BN K07058 - - 0.00000000000000000000000006793 114.0
HFD1_k127_983393_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.073e-305 950.0
HFD1_k127_983393_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 421.0
HFD1_k127_983393_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000003276 148.0
HFD1_k127_983393_3 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000005821 127.0
HFD1_k127_983393_4 - - - - 0.000000000003659 72.0
HFD1_k127_990687_0 Dead deah box helicase domain protein K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 561.0
HFD1_k127_990687_1 Predicted membrane protein (DUF2243) - - - 0.0000000000000000002361 96.0
HFD1_k127_990687_2 - - - - 0.000000000000001143 81.0
HFD1_k127_995326_0 TIGRFAM maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 294.0
HFD1_k127_995326_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000119 193.0
HFD1_k127_995326_2 Lytic murein transglycosylase B K08305 - - 0.00000000000000000000000000000000000000001218 158.0
HFD1_k127_997661_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 8.305e-257 798.0
HFD1_k127_997661_1 FtsJ-like methyltransferase K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000001739 251.0
HFD1_k127_998117_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 347.0
HFD1_k127_998117_1 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000003219 141.0
HFD1_k127_998117_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000007973 107.0
HFD1_k127_999957_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 533.0
HFD1_k127_999957_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 326.0
HFD1_k127_999957_2 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000002075 153.0