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Overview

ID MAG01608
Name HFD1_bin.13
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_E
Class Deferrimicrobia
Order Deferrimicrobiales
Family Deferrimicrobiaceae
Genus
Species
Assembly information
Completeness (%) 56.44
Contamination (%) 0.07
GC content (%) 68.0
N50 (bp) 10,926
Genome size (bp) 1,414,591

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1324

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1014404_0 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003364 285.0
HFD1_k127_1014404_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000003289 201.0
HFD1_k127_1014404_2 oligosaccharyl transferase activity - - - 0.000000000000000000000000001724 129.0
HFD1_k127_1014404_3 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000001041 60.0
HFD1_k127_103727_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K00533 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 539.0
HFD1_k127_103727_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 395.0
HFD1_k127_103727_2 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000374 208.0
HFD1_k127_103727_3 Putative member of DMT superfamily (DUF486) - - - 0.00000000000000000000000000000000000000000000002115 171.0
HFD1_k127_103727_4 respiratory electron transport chain K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000002883 107.0
HFD1_k127_1044876_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 2.632e-259 818.0
HFD1_k127_1044876_1 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 524.0
HFD1_k127_1044876_10 STAS domain - - - 0.00000000000000006056 90.0
HFD1_k127_1044876_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000009587 85.0
HFD1_k127_1044876_12 cheY-homologous receiver domain - - - 0.00000000000004923 83.0
HFD1_k127_1044876_13 Rubrerythrin - - - 0.00001459 53.0
HFD1_k127_1044876_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 402.0
HFD1_k127_1044876_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 398.0
HFD1_k127_1044876_4 Methyl-accepting chemotaxis protein (MCP) signalling domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 326.0
HFD1_k127_1044876_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002583 289.0
HFD1_k127_1044876_6 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000008375 227.0
HFD1_k127_1044876_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000009839 219.0
HFD1_k127_1044876_8 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000117 199.0
HFD1_k127_1044876_9 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000001073 191.0
HFD1_k127_1079867_0 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 520.0
HFD1_k127_1079867_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 493.0
HFD1_k127_1079867_10 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000000001485 86.0
HFD1_k127_1079867_11 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K14261 - - 0.0000000000005831 69.0
HFD1_k127_1079867_12 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000002655 66.0
HFD1_k127_1079867_2 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 462.0
HFD1_k127_1079867_3 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 418.0
HFD1_k127_1079867_4 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 413.0
HFD1_k127_1079867_5 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 378.0
HFD1_k127_1079867_6 PFAM Pyruvate ketoisovalerate oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000002182 199.0
HFD1_k127_1079867_7 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000002299 170.0
HFD1_k127_1079867_8 2-hydroxyglutaryl-CoA dehydratase, D-component K04112,K20026 - 1.3.7.8,4.2.1.157 0.0000000000000000000000000000000859 142.0
HFD1_k127_1079867_9 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000003541 125.0
HFD1_k127_1084199_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1716.0
HFD1_k127_1084199_1 Glycosyltransferase family 20 K16055 - 2.4.1.15,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 482.0
HFD1_k127_1084199_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 408.0
HFD1_k127_1084199_3 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 362.0
HFD1_k127_1084199_4 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002547 230.0
HFD1_k127_1084199_5 MaoC like domain - - - 0.00000000006405 64.0
HFD1_k127_1112358_0 Belongs to the CarB family K01955 - 6.3.5.5 3.023e-292 915.0
HFD1_k127_1112358_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.514e-196 653.0
HFD1_k127_1112358_2 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 423.0
HFD1_k127_1191726_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 632.0
HFD1_k127_1191726_1 belongs to the aldehyde dehydrogenase family K00128,K00131,K00135,K00140 - 1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 545.0
HFD1_k127_1191726_10 heavy metal transport detoxification protein - - - 0.00000006159 60.0
HFD1_k127_1191726_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 485.0
HFD1_k127_1191726_3 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 345.0
HFD1_k127_1191726_4 peptidase M29 K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 336.0
HFD1_k127_1191726_5 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001614 257.0
HFD1_k127_1191726_6 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000001487 241.0
HFD1_k127_1191726_7 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000007096 114.0
HFD1_k127_1191726_8 snoRNA binding - - - 0.00000000000002886 77.0
HFD1_k127_1191726_9 outer membrane efflux protein - - - 0.00000001923 62.0
HFD1_k127_1254513_0 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 572.0
HFD1_k127_1254513_1 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 490.0
HFD1_k127_1254513_2 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000787 257.0
HFD1_k127_1254513_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000002416 168.0
HFD1_k127_1254513_4 Cold shock protein K03704 - - 0.00000000000000000000001051 101.0
HFD1_k127_1254513_5 oxidoreductase - - - 0.0000000000657 67.0
HFD1_k127_1254513_6 Cell division protein K03591 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0031224,GO:0031226,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.00001084 56.0
HFD1_k127_1254513_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00004089 51.0
HFD1_k127_1266744_0 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 496.0
HFD1_k127_1266744_1 response regulator K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 477.0
HFD1_k127_1266744_10 Unextendable partial coding region - - - 0.000000000000003944 76.0
HFD1_k127_1266744_11 Domain of unknown function (DUF4390) - - - 0.00000000001251 72.0
HFD1_k127_1266744_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 451.0
HFD1_k127_1266744_3 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 317.0
HFD1_k127_1266744_4 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000001159 258.0
HFD1_k127_1266744_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000143 254.0
HFD1_k127_1266744_6 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000006141 156.0
HFD1_k127_1266744_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000002339 150.0
HFD1_k127_1266744_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000465 151.0
HFD1_k127_1266744_9 Protein of unknown function (DUF2905) - - - 0.00000000000000000009917 90.0
HFD1_k127_1318145_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.373e-271 851.0
HFD1_k127_1318145_1 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 521.0
HFD1_k127_1318145_2 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 492.0
HFD1_k127_1318145_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 461.0
HFD1_k127_1318145_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 399.0
HFD1_k127_1318145_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 371.0
HFD1_k127_1318145_6 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 314.0
HFD1_k127_1318145_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000006897 227.0
HFD1_k127_1318145_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000006342 234.0
HFD1_k127_1318145_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790,K19997 - 1.1.1.133,5.1.3.13,5.1.3.26 0.0000000000000000000000000000000000000000000000001079 184.0
HFD1_k127_1476056_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 9.186e-200 631.0
HFD1_k127_1476056_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 454.0
HFD1_k127_1476056_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 395.0
HFD1_k127_1476056_3 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 392.0
HFD1_k127_1476056_4 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 377.0
HFD1_k127_1476056_5 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 312.0
HFD1_k127_1476056_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 317.0
HFD1_k127_1476056_7 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 313.0
HFD1_k127_1476056_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000001626 268.0
HFD1_k127_1499091_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 5.224e-216 683.0
HFD1_k127_1499091_1 associated with various cellular activities K03695,K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 541.0
HFD1_k127_1499091_10 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00002798 48.0
HFD1_k127_1499091_2 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 369.0
HFD1_k127_1499091_3 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000001406 192.0
HFD1_k127_1499091_4 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000001053 184.0
HFD1_k127_1499091_5 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000004732 166.0
HFD1_k127_1499091_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000003193 163.0
HFD1_k127_1499091_7 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000004198 125.0
HFD1_k127_1499091_8 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000001082 65.0
HFD1_k127_1499091_9 DJ-1/PfpI family K05520 - 3.5.1.124 0.00001036 48.0
HFD1_k127_1499256_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 541.0
HFD1_k127_1499256_1 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000253 194.0
HFD1_k127_1499256_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000214 171.0
HFD1_k127_1499256_3 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000002314 155.0
HFD1_k127_1499256_4 Thioredoxin-like - - - 0.000000000000000000000000000000000316 141.0
HFD1_k127_1499256_5 methyltransferase - - - 0.00000000000000000000000000000001285 137.0
HFD1_k127_1499256_6 HEAT repeat - - - 0.00000000000000000000000000000395 133.0
HFD1_k127_1499256_7 PFAM Glycosyl transferase family 2 K20534 - - 0.0000003658 60.0
HFD1_k127_1509339_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 376.0
HFD1_k127_1509339_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000003651 236.0
HFD1_k127_1509339_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000543 236.0
HFD1_k127_1509339_3 Branched-chain amino acid ABC transporter substrate-binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000001833 226.0
HFD1_k127_1512359_0 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 477.0
HFD1_k127_1512359_1 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 360.0
HFD1_k127_1512359_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004316 282.0
HFD1_k127_1512359_3 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000005722 183.0
HFD1_k127_1512359_4 Uncharacterized small protein (DUF2292) - - - 0.000000002229 61.0
HFD1_k127_1605139_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 472.0
HFD1_k127_1605139_1 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 370.0
HFD1_k127_1605139_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 338.0
HFD1_k127_1605139_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000009386 191.0
HFD1_k127_1605139_4 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000001702 182.0
HFD1_k127_1605139_5 CAAX protease self-immunity K07052 - - 0.00000000001531 74.0
HFD1_k127_1660587_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 531.0
HFD1_k127_1660587_1 Chase2 domain K01768,K07814 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 505.0
HFD1_k127_1660587_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 477.0
HFD1_k127_1660587_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 332.0
HFD1_k127_1660587_4 chlorophyll binding K03286 - - 0.0000000000000000000000000000000002033 145.0
HFD1_k127_1660587_5 FecR protein - - - 0.000000000000000000000000000000001266 135.0
HFD1_k127_1670472_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1344.0
HFD1_k127_1670472_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 571.0
HFD1_k127_1670472_2 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 487.0
HFD1_k127_1670472_3 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 459.0
HFD1_k127_1670472_4 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 425.0
HFD1_k127_1686292_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.289e-200 656.0
HFD1_k127_1686292_1 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 589.0
HFD1_k127_1686292_10 PFAM Appr-1-p processing - - - 0.0000000000000000000000000000000000000000000000000000000000001078 222.0
HFD1_k127_1686292_11 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000001647 191.0
HFD1_k127_1686292_12 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000001207 173.0
HFD1_k127_1686292_13 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000002964 162.0
HFD1_k127_1686292_14 iron ion homeostasis - - - 0.000000000000000000000000000000000002872 157.0
HFD1_k127_1686292_15 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000004306 145.0
HFD1_k127_1686292_16 cell redox homeostasis - - - 0.0000000000000000000000000000000003509 139.0
HFD1_k127_1686292_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000005865 135.0
HFD1_k127_1686292_18 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000005434 123.0
HFD1_k127_1686292_19 - - - - 0.000000000000005105 81.0
HFD1_k127_1686292_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 498.0
HFD1_k127_1686292_20 RDD family - - - 0.0000000000004495 77.0
HFD1_k127_1686292_21 - - - - 0.000000000005024 77.0
HFD1_k127_1686292_23 Anti-sigma-K factor rskA - - - 0.00005762 51.0
HFD1_k127_1686292_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 504.0
HFD1_k127_1686292_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 458.0
HFD1_k127_1686292_5 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 401.0
HFD1_k127_1686292_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 351.0
HFD1_k127_1686292_7 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 337.0
HFD1_k127_1686292_8 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 260.0
HFD1_k127_1686292_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000001151 243.0
HFD1_k127_169496_0 nitric oxide reductase activity K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 586.0
HFD1_k127_169496_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 431.0
HFD1_k127_169496_10 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000001088 145.0
HFD1_k127_169496_11 - - - - 0.0000225 54.0
HFD1_k127_169496_12 - - - - 0.0007193 49.0
HFD1_k127_169496_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 334.0
HFD1_k127_169496_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 325.0
HFD1_k127_169496_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002261 304.0
HFD1_k127_169496_5 TIGRFAM phosphate ABC transporter K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005412 286.0
HFD1_k127_169496_6 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000009325 242.0
HFD1_k127_169496_7 ATP corrinoid adenosyltransferase K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000009891 209.0
HFD1_k127_169496_8 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000001436 190.0
HFD1_k127_169496_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000001404 164.0
HFD1_k127_1752932_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.567e-238 742.0
HFD1_k127_1752932_1 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 1.344e-213 681.0
HFD1_k127_1752932_2 DNA polymerase K02347 - - 3.471e-205 664.0
HFD1_k127_1752932_3 PFAM Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 569.0
HFD1_k127_1752932_4 Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000004117 175.0
HFD1_k127_1752932_5 electron transport K00196,K05796 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000003216 157.0
HFD1_k127_1752932_6 RDD family - - - 0.000000000000000000000000000000002544 144.0
HFD1_k127_1752932_7 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000001068 141.0
HFD1_k127_1789847_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 1.164e-256 804.0
HFD1_k127_1789847_1 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.192e-219 693.0
HFD1_k127_1789847_10 Diguanylate cyclase - - - 0.000000000000000000000000000000000001605 151.0
HFD1_k127_1789847_11 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000005 146.0
HFD1_k127_1789847_12 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000001193 147.0
HFD1_k127_1789847_13 membrane transporter protein K07090 - - 0.0000000001797 67.0
HFD1_k127_1789847_14 denitrification pathway - - - 0.0004055 49.0
HFD1_k127_1789847_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 350.0
HFD1_k127_1789847_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 323.0
HFD1_k127_1789847_4 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 317.0
HFD1_k127_1789847_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003755 273.0
HFD1_k127_1789847_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000001617 287.0
HFD1_k127_1789847_7 LUD domain - - - 0.000000000000000000000000000000000000000000000000000000003522 213.0
HFD1_k127_1789847_8 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000007928 188.0
HFD1_k127_1789847_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000001083 166.0
HFD1_k127_1792193_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 581.0
HFD1_k127_1792193_1 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 559.0
HFD1_k127_1792193_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000001596 112.0
HFD1_k127_1792193_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 0.00000000000000002564 83.0
HFD1_k127_1792193_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 463.0
HFD1_k127_1792193_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 455.0
HFD1_k127_1792193_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 421.0
HFD1_k127_1792193_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
HFD1_k127_1792193_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000001558 205.0
HFD1_k127_1792193_7 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000001173 198.0
HFD1_k127_1792193_8 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.000000000000000000000000000002068 130.0
HFD1_k127_1792193_9 YbbR-like protein - - - 0.00000000000000000000000000002128 134.0
HFD1_k127_1888851_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1086.0
HFD1_k127_1888851_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 5.953e-268 837.0
HFD1_k127_1888851_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000005045 218.0
HFD1_k127_1888851_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003887 213.0
HFD1_k127_1888851_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000006153 68.0
HFD1_k127_190843_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 407.0
HFD1_k127_190843_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 405.0
HFD1_k127_190843_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 389.0
HFD1_k127_190843_3 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 330.0
HFD1_k127_190843_4 ABC transporter K01996,K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002098 295.0
HFD1_k127_190843_5 Domain of unknown function (DUF4153) - - - 0.000000000000000000000000000000000000000000000000000000000000000007484 247.0
HFD1_k127_190843_6 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000002825 156.0
HFD1_k127_190843_7 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000001232 149.0
HFD1_k127_190843_8 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000002536 76.0
HFD1_k127_1965666_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.542e-227 732.0
HFD1_k127_1965666_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 576.0
HFD1_k127_1965666_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 452.0
HFD1_k127_1965666_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 302.0
HFD1_k127_1965666_4 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008312 278.0
HFD1_k127_1965666_5 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002472 284.0
HFD1_k127_1965666_6 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000007377 176.0
HFD1_k127_1965666_7 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000003346 121.0
HFD1_k127_1965666_8 Cytidylate kinase K00945 - 2.7.4.25 0.000000000000000000000000242 109.0
HFD1_k127_2191246_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1124.0
HFD1_k127_2191246_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 548.0
HFD1_k127_2191246_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000003826 239.0
HFD1_k127_2191246_3 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000001566 215.0
HFD1_k127_2191246_4 metal cluster binding K06940,K18475 - - 0.0000000000000000000000000002724 124.0
HFD1_k127_2191246_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000008022 93.0
HFD1_k127_2191246_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000000009297 77.0
HFD1_k127_2191246_7 Carbonic anhydrase K01673 - 4.2.1.1 0.0002764 51.0
HFD1_k127_2193077_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 621.0
HFD1_k127_2193077_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 507.0
HFD1_k127_2193077_10 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000005537 103.0
HFD1_k127_2193077_12 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000005285 63.0
HFD1_k127_2193077_13 Cell division protein FtsL - - - 0.000001141 55.0
HFD1_k127_2193077_14 - - - - 0.00001629 48.0
HFD1_k127_2193077_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 336.0
HFD1_k127_2193077_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001094 287.0
HFD1_k127_2193077_4 TIGRFAM dinuclear metal center protein, YbgI SA1388 family - - - 0.00000000000000000000000000000000000000000000000000000000000007931 229.0
HFD1_k127_2193077_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000001991 177.0
HFD1_k127_2193077_6 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000001439 157.0
HFD1_k127_2193077_7 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000001189 155.0
HFD1_k127_2193077_8 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000004893 134.0
HFD1_k127_2193077_9 Reverse transcriptase-like K03469,K06864,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000000000000000001728 136.0
HFD1_k127_2290019_0 aconitate hydratase K01681 - 4.2.1.3 2.468e-315 987.0
HFD1_k127_2290019_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 408.0
HFD1_k127_2290019_2 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 341.0
HFD1_k127_2290019_3 PFAM OmpA MotB domain protein K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000006137 250.0
HFD1_k127_2290019_4 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000003076 228.0
HFD1_k127_2290019_5 - - - - 0.0000000000000000000002297 99.0
HFD1_k127_2380522_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003951 263.0
HFD1_k127_2380522_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000002777 237.0
HFD1_k127_2380522_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000001322 207.0
HFD1_k127_2380522_3 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000003462 192.0
HFD1_k127_2381146_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 527.0
HFD1_k127_2381146_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 400.0
HFD1_k127_2381146_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 392.0
HFD1_k127_2381146_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 336.0
HFD1_k127_2381146_4 Metal-dependent phosphohydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 328.0
HFD1_k127_2381146_5 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000008079 121.0
HFD1_k127_2381146_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000007531 92.0
HFD1_k127_2481149_0 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 626.0
HFD1_k127_2481149_1 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 556.0
HFD1_k127_2481149_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 494.0
HFD1_k127_2481149_3 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 428.0
HFD1_k127_2481149_4 TIGRFAM sulfate ABC transporter, inner membrane subunit CysT K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 414.0
HFD1_k127_2481149_5 Binding-protein-dependent transport system inner membrane component K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 426.0
HFD1_k127_2481149_6 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 352.0
HFD1_k127_2481149_7 Belongs to the PAPS reductase family. CysH subfamily K00366,K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.7.7.1,1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003503 294.0
HFD1_k127_2559516_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 347.0
HFD1_k127_2559516_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 314.0
HFD1_k127_2559516_2 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000464 289.0
HFD1_k127_2559516_3 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000001547 151.0
HFD1_k127_2559516_4 Protein of unknown function (DUF3426) - - - 0.000000000000000003511 99.0
HFD1_k127_2559516_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000001211 81.0
HFD1_k127_2562684_0 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 433.0
HFD1_k127_2562684_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K21025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 340.0
HFD1_k127_2562684_2 cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000393 196.0
HFD1_k127_2562684_3 PBS lyase HEAT-like repeat - - - 0.0000000000000005181 93.0
HFD1_k127_2562684_4 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K13014 GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - 0.00002999 51.0
HFD1_k127_2642782_0 Histidine kinase K10715,K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 627.0
HFD1_k127_2642782_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 492.0
HFD1_k127_2642782_2 4Fe-4S dicluster domain K00124 GO:0005575,GO:0005623,GO:0009326,GO:0032991,GO:0042597,GO:0044464,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 407.0
HFD1_k127_2642782_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 333.0
HFD1_k127_2642782_4 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 316.0
HFD1_k127_2642782_5 Enoyl-CoA hydratase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001702 283.0
HFD1_k127_2642782_6 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
HFD1_k127_2642782_7 Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006492 283.0
HFD1_k127_2642782_8 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03753,K13818 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000004194 232.0
HFD1_k127_2642782_9 Alcohol dehydrogenase GroES-like domain K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000581 222.0
HFD1_k127_276297_0 Glucodextranase, domain N K01178 - 3.2.1.3 3.593e-230 724.0
HFD1_k127_276297_1 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 565.0
HFD1_k127_276297_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 386.0
HFD1_k127_276297_3 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 380.0
HFD1_k127_276297_4 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000317 143.0
HFD1_k127_2772264_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.796e-279 898.0
HFD1_k127_2772264_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 387.0
HFD1_k127_2772264_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 326.0
HFD1_k127_2772264_3 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 306.0
HFD1_k127_2772264_4 nucleotide-excision repair K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000201 179.0
HFD1_k127_2772264_5 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000322 173.0
HFD1_k127_2772264_6 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000004376 109.0
HFD1_k127_2772264_7 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.000000000000001884 91.0
HFD1_k127_2772264_8 DinB superfamily - - - 0.000003415 60.0
HFD1_k127_2772264_9 Tetratricopeptide repeat - - - 0.000005128 56.0
HFD1_k127_2791082_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 6.173e-236 750.0
HFD1_k127_2791082_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.422e-208 657.0
HFD1_k127_2791082_10 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000001136 79.0
HFD1_k127_2791082_11 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000006735 53.0
HFD1_k127_2791082_12 - - - - 0.00011 53.0
HFD1_k127_2791082_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 7.939e-208 658.0
HFD1_k127_2791082_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 585.0
HFD1_k127_2791082_4 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 360.0
HFD1_k127_2791082_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000001611 214.0
HFD1_k127_2791082_6 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000001634 188.0
HFD1_k127_2791082_7 Domain of unknown function (DUF4124) K08309 - - 0.000000000000000000000000000000000000000000001821 171.0
HFD1_k127_2791082_8 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006509 132.0
HFD1_k127_2791082_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000003518 93.0
HFD1_k127_2859627_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1399.0
HFD1_k127_2859627_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 460.0
HFD1_k127_2859627_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 448.0
HFD1_k127_2859627_3 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 348.0
HFD1_k127_2859627_4 sigma factor activity K02405,K03093 - - 0.000000000000000000000000000000000000000000000000000000000012 215.0
HFD1_k127_2859627_5 RmuC family K09760 - - 0.0000000000000000000000000000000003801 145.0
HFD1_k127_2859627_6 Zincin-like metallopeptidase - - - 0.0000000000000000000007776 110.0
HFD1_k127_2878855_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.353e-226 711.0
HFD1_k127_2878855_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 520.0
HFD1_k127_2878855_10 quinone binding K00337 - 1.6.5.3 0.00000000000003165 86.0
HFD1_k127_2878855_2 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 478.0
HFD1_k127_2878855_3 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 435.0
HFD1_k127_2878855_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 424.0
HFD1_k127_2878855_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000007625 217.0
HFD1_k127_2878855_6 NADH-quinone oxidoreductase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002591 190.0
HFD1_k127_2878855_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000005664 191.0
HFD1_k127_2878855_8 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000009512 139.0
HFD1_k127_2878855_9 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000006806 102.0
HFD1_k127_2903169_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000003059 251.0
HFD1_k127_2903169_1 Cytochrome c554 and c-prime - - - 0.00000000005878 73.0
HFD1_k127_2963483_0 Conserved carboxylase domain K01958 - 6.4.1.1 6.78e-218 717.0
HFD1_k127_2963483_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 542.0
HFD1_k127_2963483_10 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006977 265.0
HFD1_k127_2963483_11 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000137 268.0
HFD1_k127_2963483_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.0000000000000000000000000000000000000000000000000000001113 210.0
HFD1_k127_2963483_13 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000006722 172.0
HFD1_k127_2963483_14 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000001413 125.0
HFD1_k127_2963483_15 Acetyltransferase (GNAT) family - - - 0.00000001116 68.0
HFD1_k127_2963483_16 Anti-sigma-28 factor, FlgM K02398 - - 0.0003244 48.0
HFD1_k127_2963483_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 521.0
HFD1_k127_2963483_3 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 510.0
HFD1_k127_2963483_4 ABC transporter transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 497.0
HFD1_k127_2963483_5 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 381.0
HFD1_k127_2963483_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 371.0
HFD1_k127_2963483_7 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 364.0
HFD1_k127_2963483_8 PFAM ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 377.0
HFD1_k127_2963483_9 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001293 278.0
HFD1_k127_2968009_0 SMART helicase c2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 488.0
HFD1_k127_2968009_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 316.0
HFD1_k127_2968009_2 PFAM Extracellular ligand-binding receptor K07121 - - 0.000005089 59.0
HFD1_k127_30775_0 Translation-initiation factor 2 K02519 - - 2.456e-235 753.0
HFD1_k127_30775_1 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 293.0
HFD1_k127_30775_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000001496 211.0
HFD1_k127_30775_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000005248 114.0
HFD1_k127_30775_4 Protein of unknown function (DUF503) K09764 - - 0.000000000004062 79.0
HFD1_k127_30775_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000003939 58.0
HFD1_k127_30775_6 Protein of unknown function (DUF448) K07742 - - 0.00000001217 62.0
HFD1_k127_3152717_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 509.0
HFD1_k127_3152717_1 transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 368.0
HFD1_k127_3152717_2 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005987 275.0
HFD1_k127_3152717_3 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001399 280.0
HFD1_k127_3152717_4 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005047 245.0
HFD1_k127_3152717_5 GTP-binding protein TypA K06207 - - 0.000000000000000000000001225 104.0
HFD1_k127_3200506_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 564.0
HFD1_k127_3200506_1 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 304.0
HFD1_k127_3200506_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000004824 171.0
HFD1_k127_3200506_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000001574 89.0
HFD1_k127_3200506_4 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000006455 67.0
HFD1_k127_3210359_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.243e-194 619.0
HFD1_k127_3210359_1 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 369.0
HFD1_k127_3210359_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005837 263.0
HFD1_k127_3210359_3 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000005238 198.0
HFD1_k127_3252555_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1088.0
HFD1_k127_3252555_1 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 488.0
HFD1_k127_3252555_10 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000003673 146.0
HFD1_k127_3252555_11 Could be involved in septation K06412 - - 0.000000000000000000000000007626 123.0
HFD1_k127_3252555_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000004908 107.0
HFD1_k127_3252555_13 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000001379 88.0
HFD1_k127_3252555_14 Domain of unknown function (DUF1844) - - - 0.000000000435 66.0
HFD1_k127_3252555_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 467.0
HFD1_k127_3252555_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 428.0
HFD1_k127_3252555_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 421.0
HFD1_k127_3252555_5 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 366.0
HFD1_k127_3252555_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000006457 185.0
HFD1_k127_3252555_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000005446 171.0
HFD1_k127_3252555_8 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000008648 156.0
HFD1_k127_3252555_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000504 147.0
HFD1_k127_3295827_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 458.0
HFD1_k127_3295827_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 464.0
HFD1_k127_3295827_10 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000321 122.0
HFD1_k127_3295827_11 ADP-ribosylglycohydrolase - - - 0.000000000000005988 88.0
HFD1_k127_3295827_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 386.0
HFD1_k127_3295827_3 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 312.0
HFD1_k127_3295827_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 295.0
HFD1_k127_3295827_5 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002784 280.0
HFD1_k127_3295827_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
HFD1_k127_3295827_7 PFAM regulatory protein TetR K13770 - - 0.0000000000000000000000000000000000000000000000000000006536 199.0
HFD1_k127_3295827_8 COG0247 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000446 154.0
HFD1_k127_3295827_9 SMART Tetratricopeptide - - - 0.00000000000000000000000001136 119.0
HFD1_k127_331273_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 509.0
HFD1_k127_331273_1 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 314.0
HFD1_k127_331273_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000008837 209.0
HFD1_k127_331273_3 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000002061 133.0
HFD1_k127_331273_4 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000006674 50.0
HFD1_k127_3351943_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 4.784e-252 786.0
HFD1_k127_3351943_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.772e-249 783.0
HFD1_k127_3351943_10 4Fe-4S dicluster domain - - - 0.0000000000000000000000000001372 123.0
HFD1_k127_3351943_11 Tetratricopeptide TPR_2 repeat protein - - - 0.00004169 57.0
HFD1_k127_3351943_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 606.0
HFD1_k127_3351943_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 484.0
HFD1_k127_3351943_4 Glycosyltransferase like family 2 K11936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 391.0
HFD1_k127_3351943_5 PFAM Polysaccharide deacetylase K11931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003591 273.0
HFD1_k127_3351943_6 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000002206 252.0
HFD1_k127_3351943_7 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000005975 213.0
HFD1_k127_3351943_8 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000003822 185.0
HFD1_k127_3351943_9 Biotin-requiring enzyme - - - 0.000000000000000000000000000000001134 135.0
HFD1_k127_3358047_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 530.0
HFD1_k127_3358047_1 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 380.0
HFD1_k127_3358047_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000001527 246.0
HFD1_k127_3358047_3 - - - - 0.0000000000000000000747 95.0
HFD1_k127_3358047_4 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000133 54.0
HFD1_k127_3358047_5 Protein of unknown function (DUF2889) - - - 0.0005955 49.0
HFD1_k127_3487216_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 513.0
HFD1_k127_3487216_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 433.0
HFD1_k127_3487216_10 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000001889 144.0
HFD1_k127_3487216_11 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000008945 79.0
HFD1_k127_3487216_2 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000001084 274.0
HFD1_k127_3487216_3 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001593 269.0
HFD1_k127_3487216_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000003921 244.0
HFD1_k127_3487216_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000307 228.0
HFD1_k127_3487216_6 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000000000000144 211.0
HFD1_k127_3487216_7 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000002943 207.0
HFD1_k127_3487216_8 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000003227 199.0
HFD1_k127_3487216_9 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000001352 180.0
HFD1_k127_3518965_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 592.0
HFD1_k127_3518965_1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 409.0
HFD1_k127_3518965_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004191 289.0
HFD1_k127_3518965_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004604 270.0
HFD1_k127_3518965_4 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000851 248.0
HFD1_k127_3518965_5 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000001527 192.0
HFD1_k127_3518965_6 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000001518 159.0
HFD1_k127_3518965_7 GlcNAc-PI de-N-acetylase K22135 - - 0.000000000000000000000000000000000001148 150.0
HFD1_k127_3695744_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.132e-203 642.0
HFD1_k127_3695744_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 548.0
HFD1_k127_3695744_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 338.0
HFD1_k127_3695744_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000003194 226.0
HFD1_k127_3695744_4 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000002291 220.0
HFD1_k127_3695744_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000003758 164.0
HFD1_k127_3695744_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000001222 163.0
HFD1_k127_3714122_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 537.0
HFD1_k127_3714122_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 420.0
HFD1_k127_3714122_2 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 410.0
HFD1_k127_3714122_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 319.0
HFD1_k127_3714122_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 302.0
HFD1_k127_3714122_5 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000000000000000000000000000667 168.0
HFD1_k127_3714122_6 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000007652 120.0
HFD1_k127_3861718_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 5.262e-260 811.0
HFD1_k127_3861718_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.449e-243 764.0
HFD1_k127_3861718_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 521.0
HFD1_k127_3861718_3 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000002345 223.0
HFD1_k127_3948769_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1182.0
HFD1_k127_3948769_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 553.0
HFD1_k127_3948769_2 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 353.0
HFD1_k127_3948769_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000005373 193.0
HFD1_k127_3948769_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.0000000000000000000000000000000000000000000001338 174.0
HFD1_k127_3948769_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000002271 155.0
HFD1_k127_3948769_6 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000685 127.0
HFD1_k127_4128738_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.985e-239 747.0
HFD1_k127_4128738_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 383.0
HFD1_k127_4128738_10 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000003239 241.0
HFD1_k127_4128738_11 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000004089 198.0
HFD1_k127_4128738_12 AAA domain K07321 - - 0.000000000000000000000000000000000000000000001142 191.0
HFD1_k127_4128738_13 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000004493 160.0
HFD1_k127_4128738_14 PFAM cytochrome c, class I K00406 - - 0.000000000000000000000000000000001859 142.0
HFD1_k127_4128738_15 - - - - 0.000000000000003137 89.0
HFD1_k127_4128738_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 380.0
HFD1_k127_4128738_3 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 360.0
HFD1_k127_4128738_4 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 354.0
HFD1_k127_4128738_5 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 361.0
HFD1_k127_4128738_6 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 338.0
HFD1_k127_4128738_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 330.0
HFD1_k127_4128738_8 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003188 279.0
HFD1_k127_4128738_9 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001213 249.0
HFD1_k127_42077_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.939e-251 826.0
HFD1_k127_42077_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 297.0
HFD1_k127_4256861_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.082e-262 825.0
HFD1_k127_4256861_1 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003296 282.0
HFD1_k127_4256861_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000005873 187.0
HFD1_k127_4256861_3 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000003454 183.0
HFD1_k127_4256861_4 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000678 160.0
HFD1_k127_4256861_5 Belongs to the UPF0434 family K09791 - - 0.00000000000000003544 83.0
HFD1_k127_4256861_6 Protein of unknown function (DUF3108) - - - 0.0000000000000001468 91.0
HFD1_k127_4256861_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000004881 75.0
HFD1_k127_4256861_8 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000002258 77.0
HFD1_k127_4263487_0 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 350.0
HFD1_k127_4263487_1 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 353.0
HFD1_k127_4263487_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000001444 256.0
HFD1_k127_4263487_3 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000001082 220.0
HFD1_k127_4263487_4 - - - - 0.0000000000000000000000000000000000005616 147.0
HFD1_k127_4263487_5 transglycosylase K08309 - - 0.0000000000000000000000006759 122.0
HFD1_k127_4263487_6 Xylose isomerase-like TIM barrel - - - 0.0000000000000004068 93.0
HFD1_k127_4291027_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1119.0
HFD1_k127_4291027_1 Required for chromosome condensation and partitioning K03529 - - 5.233e-194 654.0
HFD1_k127_4291027_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 617.0
HFD1_k127_4291027_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 519.0
HFD1_k127_4291027_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 321.0
HFD1_k127_4291027_5 phosphoenolpyruvate-protein phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000001076 188.0
HFD1_k127_4291027_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000003535 91.0
HFD1_k127_4291027_7 Na Pi-cotransporter II-like protein K03324 - - 0.000000000000002268 81.0
HFD1_k127_4291027_8 Domain of unknown function (DUF4115) - - - 0.00001409 51.0
HFD1_k127_4367287_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1036.0
HFD1_k127_4367287_1 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 9.237e-196 619.0
HFD1_k127_4367287_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004918 232.0
HFD1_k127_4367287_11 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000007221 222.0
HFD1_k127_4367287_12 - - - - 0.000000000000000000000000000000000000000000000000000000248 197.0
HFD1_k127_4367287_13 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000003532 146.0
HFD1_k127_4367287_14 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000002161 140.0
HFD1_k127_4367287_16 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000001054 70.0
HFD1_k127_4367287_17 - - - - 0.0000008099 59.0
HFD1_k127_4367287_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 576.0
HFD1_k127_4367287_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 518.0
HFD1_k127_4367287_4 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 451.0
HFD1_k127_4367287_5 Sir2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 394.0
HFD1_k127_4367287_6 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 357.0
HFD1_k127_4367287_7 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 294.0
HFD1_k127_4367287_8 Histidine kinase A domain protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001105 280.0
HFD1_k127_4367287_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002385 248.0
HFD1_k127_4479653_0 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 564.0
HFD1_k127_4479653_3 histidine kinase - - - 0.0002061 44.0
HFD1_k127_4599592_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K00344,K00966,K01840,K03431,K15778,K16881 - 1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8 2.155e-278 880.0
HFD1_k127_4599592_1 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 508.0
HFD1_k127_4599592_10 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000003661 196.0
HFD1_k127_4599592_11 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000005728 192.0
HFD1_k127_4599592_12 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000001918 177.0
HFD1_k127_4599592_13 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000003572 155.0
HFD1_k127_4599592_14 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000002576 157.0
HFD1_k127_4599592_15 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000001811 138.0
HFD1_k127_4599592_16 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000006113 149.0
HFD1_k127_4599592_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000007282 144.0
HFD1_k127_4599592_18 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000003194 110.0
HFD1_k127_4599592_19 Domain of unknown function (DUF1858) - - - 0.00000000000000000008103 91.0
HFD1_k127_4599592_2 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 405.0
HFD1_k127_4599592_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 379.0
HFD1_k127_4599592_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 299.0
HFD1_k127_4599592_5 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
HFD1_k127_4599592_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000259 228.0
HFD1_k127_4599592_7 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000003883 223.0
HFD1_k127_4599592_8 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000007285 201.0
HFD1_k127_4599592_9 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000001932 219.0
HFD1_k127_4826793_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.914e-271 847.0
HFD1_k127_4826793_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 451.0
HFD1_k127_4826793_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000003521 155.0
HFD1_k127_4826793_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000001149 157.0
HFD1_k127_4870438_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.423e-260 814.0
HFD1_k127_4870438_1 TIGRFAM cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 394.0
HFD1_k127_4870438_10 Outer membrane protein beta-barrel domain - - - 0.000189 51.0
HFD1_k127_4870438_2 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009396 323.0
HFD1_k127_4870438_3 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000006664 228.0
HFD1_k127_4870438_4 Putative RNA methylase family UPF0020 K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000001752 174.0
HFD1_k127_4870438_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000002072 177.0
HFD1_k127_4870438_6 Competence protein - - - 0.00000000000000000003109 94.0
HFD1_k127_4870438_7 - - - - 0.00000000000000001043 85.0
HFD1_k127_4870438_8 Protein of unknown function (DUF3343) - - - 0.00000000000006419 75.0
HFD1_k127_4870438_9 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00001269 55.0
HFD1_k127_4889314_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1043.0
HFD1_k127_4889314_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 5.677e-236 736.0
HFD1_k127_4889314_2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 402.0
HFD1_k127_4889314_3 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000006018 182.0
HFD1_k127_4889314_4 - - - - 0.0000000000000000000000007905 120.0
HFD1_k127_4889314_5 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000000001723 87.0
HFD1_k127_4889314_6 Subtilase family - - - 0.00000000000003998 85.0
HFD1_k127_492753_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 593.0
HFD1_k127_492753_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 458.0
HFD1_k127_492753_10 PFAM methyltransferase - - - 0.00000000000012 82.0
HFD1_k127_492753_11 Caenorhabditis protein of unknown function, DUF268 - - - 0.00000000001796 74.0
HFD1_k127_492753_12 PFAM Glycosyl transferase, group 1 - - - 0.0001203 51.0
HFD1_k127_492753_2 PFAM ABC transporter K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 413.0
HFD1_k127_492753_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 302.0
HFD1_k127_492753_4 transport, permease protein K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 295.0
HFD1_k127_492753_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 315.0
HFD1_k127_492753_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005237 269.0
HFD1_k127_492753_7 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002453 235.0
HFD1_k127_492753_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000008551 188.0
HFD1_k127_4970672_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.174e-309 953.0
HFD1_k127_4970672_1 Citrate lyase, alpha subunit (CitF) - - - 2.835e-279 874.0
HFD1_k127_4970672_2 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 352.0
HFD1_k127_4970672_3 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000003432 211.0
HFD1_k127_4970672_4 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000004064 198.0
HFD1_k127_4970672_5 Divergent 4Fe-4S mono-cluster K05337 - - 0.0000000000000000000000006362 105.0
HFD1_k127_4970672_6 Lipoprotein - - - 0.00000000005752 71.0
HFD1_k127_4970672_7 Histidine kinase - - - 0.000006697 56.0
HFD1_k127_5017674_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 517.0
HFD1_k127_5017674_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 382.0
HFD1_k127_5017674_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 340.0
HFD1_k127_5017674_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000006167 183.0
HFD1_k127_5017674_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000001983 153.0
HFD1_k127_5017674_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000009967 136.0
HFD1_k127_5017674_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000003267 130.0
HFD1_k127_5017674_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000004951 91.0
HFD1_k127_5017674_8 Competence protein - - - 0.0001181 52.0
HFD1_k127_5032438_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 479.0
HFD1_k127_5032438_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 301.0
HFD1_k127_5032438_2 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 304.0
HFD1_k127_5032438_3 lysyl-tRNA synthetase K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000299 239.0
HFD1_k127_5032438_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000007689 124.0
HFD1_k127_5032438_5 amidohydrolase K07045 - - 0.000000000000000000000104 111.0
HFD1_k127_5032438_6 PFAM HlyD family secretion protein K01993,K03543 - - 0.0000000000000002883 87.0
HFD1_k127_5054859_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 447.0
HFD1_k127_5054859_1 PFAM Cys Met metabolism K01739,K01760 - 2.5.1.48,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 419.0
HFD1_k127_5054859_10 Ferric uptake regulator family K03711 - - 0.00000000000002446 85.0
HFD1_k127_5054859_11 ABC transporter K09817 - - 0.000000000003803 73.0
HFD1_k127_5054859_12 integral membrane protein - - - 0.00001337 54.0
HFD1_k127_5054859_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 302.0
HFD1_k127_5054859_3 penicillin-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 267.0
HFD1_k127_5054859_4 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000002292 219.0
HFD1_k127_5054859_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000002504 210.0
HFD1_k127_5054859_6 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000007149 151.0
HFD1_k127_5054859_7 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000001102 119.0
HFD1_k127_5054859_8 Transcriptional regulator - - - 0.0000000000000000000002179 102.0
HFD1_k127_5054859_9 Thioesterase K01075 - 3.1.2.23 0.0000000000000000004271 100.0
HFD1_k127_5081002_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 416.0
HFD1_k127_5081002_1 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 334.0
HFD1_k127_5081002_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 327.0
HFD1_k127_5081002_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 326.0
HFD1_k127_5081002_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007172 292.0
HFD1_k127_5307105_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 468.0
HFD1_k127_5307105_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 384.0
HFD1_k127_5307105_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003179 278.0
HFD1_k127_5307105_3 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000008316 149.0
HFD1_k127_5307105_4 - - - - 0.000000000000000000000001029 108.0
HFD1_k127_5307105_5 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000009838 84.0
HFD1_k127_5307105_6 Peptidase family M23 K21471 - - 0.00000000000008113 85.0
HFD1_k127_5307105_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000005352 77.0
HFD1_k127_5307105_8 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000009939 58.0
HFD1_k127_5327407_0 General secretory system II, protein E domain protein K02652 - - 6.313e-237 744.0
HFD1_k127_5327407_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 576.0
HFD1_k127_5327407_10 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000009637 174.0
HFD1_k127_5327407_11 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000003452 92.0
HFD1_k127_5327407_12 antisigma factor binding - - - 0.000000000000000003866 88.0
HFD1_k127_5327407_2 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 507.0
HFD1_k127_5327407_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 411.0
HFD1_k127_5327407_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 351.0
HFD1_k127_5327407_5 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
HFD1_k127_5327407_6 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002991 273.0
HFD1_k127_5327407_7 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000001412 242.0
HFD1_k127_5327407_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.0000000000000000000000000000000000000000000001768 178.0
HFD1_k127_5327407_9 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000002937 184.0
HFD1_k127_5342792_0 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000004759 182.0
HFD1_k127_5342792_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000002155 157.0
HFD1_k127_5342792_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000001005 145.0
HFD1_k127_5348456_0 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 6.732e-227 728.0
HFD1_k127_5348456_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 534.0
HFD1_k127_5348456_10 SNARE associated Golgi protein K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 291.0
HFD1_k127_5348456_11 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003517 260.0
HFD1_k127_5348456_12 Butirosin biosynthesis protein H, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000003255 231.0
HFD1_k127_5348456_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000007887 145.0
HFD1_k127_5348456_14 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000009062 138.0
HFD1_k127_5348456_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 452.0
HFD1_k127_5348456_3 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 452.0
HFD1_k127_5348456_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 381.0
HFD1_k127_5348456_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 387.0
HFD1_k127_5348456_6 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 377.0
HFD1_k127_5348456_7 Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 360.0
HFD1_k127_5348456_8 Flavin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 320.0
HFD1_k127_5348456_9 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 331.0
HFD1_k127_5370196_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 9.242e-249 805.0
HFD1_k127_5370196_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 483.0
HFD1_k127_5370196_10 PAS fold - - - 0.00000000000004688 82.0
HFD1_k127_5370196_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 435.0
HFD1_k127_5370196_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 418.0
HFD1_k127_5370196_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 381.0
HFD1_k127_5370196_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003631 275.0
HFD1_k127_5370196_6 Dimerisation domain of Zinc Transporter K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001143 257.0
HFD1_k127_5370196_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000004625 240.0
HFD1_k127_5370196_8 PFAM Isochorismatase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000008685 193.0
HFD1_k127_5370196_9 transcription factor binding K11527,K14986 - 2.7.13.3 0.00000000000000000000000000006067 127.0
HFD1_k127_5497439_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1051.0
HFD1_k127_5497439_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 434.0
HFD1_k127_5497439_2 translation initiation factor activity K03646 - - 0.00000000000000000000000000000000000005194 148.0
HFD1_k127_5497439_3 response regulator - - - 0.00000000000000000000000000000164 136.0
HFD1_k127_5497439_4 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000001279 107.0
HFD1_k127_5531227_0 SPFH domain / Band 7 family - - - 3.173e-275 864.0
HFD1_k127_5531227_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 3.236e-224 701.0
HFD1_k127_5531227_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 391.0
HFD1_k127_5531227_3 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 313.0
HFD1_k127_5531227_4 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000008152 251.0
HFD1_k127_5531227_5 - - - - 0.000000000000000000000001215 118.0
HFD1_k127_5531227_6 Domain of unknown function DUF302 - - - 0.0000000000000000000000311 105.0
HFD1_k127_5531227_7 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000002202 87.0
HFD1_k127_5531227_8 Protein of unknown function (DUF2892) - - - 0.000000000000000008595 85.0
HFD1_k127_5531227_9 Putative regulatory protein - - - 0.000001357 52.0
HFD1_k127_5533952_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1252.0
HFD1_k127_5533952_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.18e-212 676.0
HFD1_k127_5533952_10 PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004901 239.0
HFD1_k127_5533952_11 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001574 248.0
HFD1_k127_5533952_12 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.000000000000000000000000000000000000000000000000000000000003199 220.0
HFD1_k127_5533952_13 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000003316 210.0
HFD1_k127_5533952_14 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000003343 224.0
HFD1_k127_5533952_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000001653 203.0
HFD1_k127_5533952_16 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000137 210.0
HFD1_k127_5533952_17 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.000000000000000000000000000000000001892 158.0
HFD1_k127_5533952_18 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000002037 153.0
HFD1_k127_5533952_19 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000002104 104.0
HFD1_k127_5533952_2 Radical SAM domain protein K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 546.0
HFD1_k127_5533952_21 Water Stress and Hypersensitive response - - - 0.0001088 54.0
HFD1_k127_5533952_22 PFAM Fibronectin type III domain - - - 0.0001393 55.0
HFD1_k127_5533952_3 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005932 504.0
HFD1_k127_5533952_4 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 481.0
HFD1_k127_5533952_5 FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 434.0
HFD1_k127_5533952_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 334.0
HFD1_k127_5533952_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 306.0
HFD1_k127_5533952_8 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 301.0
HFD1_k127_5533952_9 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001117 301.0
HFD1_k127_5550503_0 Major Facilitator Superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 445.0
HFD1_k127_5550503_1 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 379.0
HFD1_k127_5550503_10 Protein of unknown function (DUF1059) - - - 0.0001461 47.0
HFD1_k127_5550503_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004893 278.0
HFD1_k127_5550503_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000001303 158.0
HFD1_k127_5550503_4 family UPF0066 K01628 - 4.1.2.17 0.00000000000000000000000000000006706 130.0
HFD1_k127_5550503_5 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000006352 106.0
HFD1_k127_5550503_6 Magnesium chelatase, subunit ChlI K03405 - 6.6.1.1 0.0000000000000000000001076 103.0
HFD1_k127_5550503_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000006689 102.0
HFD1_k127_5550503_8 NADPH-dependent FMN reductase - - - 0.00000000000006101 76.0
HFD1_k127_5657566_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.654e-198 644.0
HFD1_k127_5657566_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 357.0
HFD1_k127_5657566_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 346.0
HFD1_k127_5657566_3 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000417 152.0
HFD1_k127_5657566_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000001355 96.0
HFD1_k127_5756153_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 544.0
HFD1_k127_5756153_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 453.0
HFD1_k127_5756153_10 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000006351 244.0
HFD1_k127_5756153_11 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000000000000001224 162.0
HFD1_k127_5756153_12 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000001889 158.0
HFD1_k127_5756153_13 PFAM YbaK prolyl-tRNA synthetases associated domain - - - 0.000000000000000000000000003726 123.0
HFD1_k127_5756153_14 Transcriptional regulator - - - 0.0000000000000000000000000268 113.0
HFD1_k127_5756153_15 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000000364 114.0
HFD1_k127_5756153_16 4Fe-4S binding domain - - - 0.0000000000000000000008549 106.0
HFD1_k127_5756153_17 signal transduction histidine kinase - - - 0.0000000000002171 76.0
HFD1_k127_5756153_2 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 440.0
HFD1_k127_5756153_3 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 396.0
HFD1_k127_5756153_4 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 313.0
HFD1_k127_5756153_5 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 296.0
HFD1_k127_5756153_6 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 293.0
HFD1_k127_5756153_7 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000179 268.0
HFD1_k127_5756153_8 extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 274.0
HFD1_k127_5756153_9 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000002636 246.0
HFD1_k127_5778871_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.746e-218 721.0
HFD1_k127_5778871_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 439.0
HFD1_k127_5778871_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 323.0
HFD1_k127_5778871_3 PFAM Silent information regulator protein Sir2 K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005897 257.0
HFD1_k127_5778871_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000007349 209.0
HFD1_k127_5778871_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000004808 164.0
HFD1_k127_5778871_6 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000007551 162.0
HFD1_k127_5778871_7 SCP-2 sterol transfer family - - - 0.00000000000000000000002607 102.0
HFD1_k127_5778871_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000008395 81.0
HFD1_k127_5832538_0 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 577.0
HFD1_k127_5832538_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 526.0
HFD1_k127_5832538_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000002551 206.0
HFD1_k127_5832538_11 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000002928 160.0
HFD1_k127_5832538_12 cytochrome c - - - 0.00000000000000000000006537 111.0
HFD1_k127_5832538_13 metal-dependent phosphohydrolase HD sub domain K07814 - - 0.0000000000000000002299 98.0
HFD1_k127_5832538_15 Protein of unknown function (DUF3341) - - - 0.0000000000001037 85.0
HFD1_k127_5832538_16 Putative regulatory protein - - - 0.000000000000287 73.0
HFD1_k127_5832538_17 Glutamine amidotransferase domain - - - 0.000000000004555 76.0
HFD1_k127_5832538_18 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000004302 63.0
HFD1_k127_5832538_2 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 441.0
HFD1_k127_5832538_3 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 344.0
HFD1_k127_5832538_4 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 353.0
HFD1_k127_5832538_5 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 325.0
HFD1_k127_5832538_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 317.0
HFD1_k127_5832538_7 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002663 284.0
HFD1_k127_5832538_8 Calcineurin-like phosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006098 269.0
HFD1_k127_5832538_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001324 247.0
HFD1_k127_5908999_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.951e-288 909.0
HFD1_k127_5908999_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 523.0
HFD1_k127_5908999_10 Modulates RecA activity K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.0003034 50.0
HFD1_k127_5908999_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 515.0
HFD1_k127_5908999_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 338.0
HFD1_k127_5908999_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000004779 172.0
HFD1_k127_5908999_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000002186 147.0
HFD1_k127_5908999_6 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000001001 137.0
HFD1_k127_5908999_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000006366 123.0
HFD1_k127_5908999_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000006835 76.0
HFD1_k127_5908999_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0002416 44.0
HFD1_k127_5917926_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1187.0
HFD1_k127_5917926_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 554.0
HFD1_k127_5917926_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000009024 145.0
HFD1_k127_5917926_11 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000004797 122.0
HFD1_k127_5917926_12 phosphorelay signal transduction system K02437 - - 0.000000000000000000000002271 111.0
HFD1_k127_5917926_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 539.0
HFD1_k127_5917926_3 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 486.0
HFD1_k127_5917926_4 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 469.0
HFD1_k127_5917926_5 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 410.0
HFD1_k127_5917926_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 320.0
HFD1_k127_5917926_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000007439 239.0
HFD1_k127_5917926_8 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000004332 154.0
HFD1_k127_5917926_9 metallopeptidase activity K06974 - - 0.000000000000000000000000000000000000602 152.0
HFD1_k127_5952815_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1113.0
HFD1_k127_5952815_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.395e-200 641.0
HFD1_k127_5952815_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 366.0
HFD1_k127_5952815_3 fumarate reductase) cytochrome b subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001145 262.0
HFD1_k127_5952815_4 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000001425 183.0
HFD1_k127_5952815_5 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000001511 132.0
HFD1_k127_5982123_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1007.0
HFD1_k127_5982123_1 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07806 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 385.0
HFD1_k127_5982123_10 acid phosphatase activity - - - 0.0000000000000003825 88.0
HFD1_k127_5982123_2 PFAM glycosyl transferase family 39 K07264 - 2.4.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 363.0
HFD1_k127_5982123_3 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 351.0
HFD1_k127_5982123_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 323.0
HFD1_k127_5982123_5 Formyl transferase, C-terminal domain K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000003799 220.0
HFD1_k127_5982123_6 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000009456 205.0
HFD1_k127_5982123_7 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000000000000000004439 162.0
HFD1_k127_5982123_8 - - - - 0.00000000000000000000000000000000000000006021 158.0
HFD1_k127_5982123_9 domain protein - - - 0.0000000000000000000000000001238 129.0
HFD1_k127_6007412_0 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 369.0
HFD1_k127_6007412_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 345.0
HFD1_k127_6007412_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002354 280.0
HFD1_k127_6007412_3 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000054 199.0
HFD1_k127_6007412_4 - - - - 0.000000000000000000000000000000000000000000000007779 182.0
HFD1_k127_6007412_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000008265 167.0
HFD1_k127_6007412_6 Phosphomethylpyrimidine kinase K00941 GO:0008150,GO:0040007 2.7.1.49,2.7.4.7 0.000000000000000000000000002755 126.0
HFD1_k127_6089605_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 466.0
HFD1_k127_6089605_1 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 301.0
HFD1_k127_6089605_2 ABC transporter K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001824 295.0
HFD1_k127_6089605_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000183 288.0
HFD1_k127_6089605_4 sulfate ABC transporter K02046 - - 0.000000000000000000000000000000000000000000000000000000001477 210.0
HFD1_k127_6089605_5 Sulfurtransferase TusA K04085 - - 0.0000008541 61.0
HFD1_k127_6089605_6 Transcriptional regulator - - - 0.000002218 51.0
HFD1_k127_6128736_0 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 439.0
HFD1_k127_6128736_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 428.0
HFD1_k127_6128736_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 434.0
HFD1_k127_6128736_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 389.0
HFD1_k127_6128736_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 375.0
HFD1_k127_6128736_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000007797 259.0
HFD1_k127_6128736_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000008805 217.0
HFD1_k127_6128736_7 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000009553 104.0
HFD1_k127_6210537_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 595.0
HFD1_k127_6210537_1 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 553.0
HFD1_k127_6210537_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 497.0
HFD1_k127_6210537_3 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 405.0
HFD1_k127_6210537_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 360.0
HFD1_k127_6210537_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 326.0
HFD1_k127_6217375_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 6.01e-243 761.0
HFD1_k127_6217375_1 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000001203 214.0
HFD1_k127_6217375_10 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.00008791 55.0
HFD1_k127_6217375_2 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000001477 198.0
HFD1_k127_6217375_3 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000004937 201.0
HFD1_k127_6217375_4 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.00000000000000000000000000000000000000000009804 181.0
HFD1_k127_6217375_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000002065 151.0
HFD1_k127_6217375_6 TPM domain K06872 - - 0.00000000000000000000000000001006 135.0
HFD1_k127_6217375_7 Cytochrome c554 and c-prime - - - 0.0000000000000000000000001467 118.0
HFD1_k127_6217375_8 nucleotidyltransferase activity - - - 0.0000000000000000002198 101.0
HFD1_k127_6217375_9 YacP-like NYN domain K06962 - - 0.0000001177 61.0
HFD1_k127_6231308_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 351.0
HFD1_k127_6231308_1 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 356.0
HFD1_k127_6231308_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000004533 230.0
HFD1_k127_6231308_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000003314 181.0
HFD1_k127_6231308_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000006733 167.0
HFD1_k127_6231308_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000002526 148.0
HFD1_k127_6231308_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000001632 53.0
HFD1_k127_6351836_0 PFAM Xanthine uracil vitamin C permease K06901 - - 5.558e-194 614.0
HFD1_k127_6351836_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 590.0
HFD1_k127_6351836_10 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000002321 179.0
HFD1_k127_6351836_11 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000006479 175.0
HFD1_k127_6351836_12 GPR1 FUN34 yaaH family protein K07034 - - 0.000000000000000000000000000000001532 137.0
HFD1_k127_6351836_13 PFAM Cyclic nucleotide-binding K10914,K21563 - - 0.00000000000000000000000000001003 128.0
HFD1_k127_6351836_14 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000002788 75.0
HFD1_k127_6351836_15 cyclic nucleotide-binding - - - 0.000002813 54.0
HFD1_k127_6351836_2 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 585.0
HFD1_k127_6351836_3 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 415.0
HFD1_k127_6351836_4 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 367.0
HFD1_k127_6351836_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 329.0
HFD1_k127_6351836_6 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002164 285.0
HFD1_k127_6351836_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000175 231.0
HFD1_k127_6351836_8 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000002399 234.0
HFD1_k127_6351836_9 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000007623 193.0
HFD1_k127_6367484_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 596.0
HFD1_k127_6367484_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 569.0
HFD1_k127_6367484_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 379.0
HFD1_k127_6367484_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001678 258.0
HFD1_k127_6367484_4 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000175 200.0
HFD1_k127_6367484_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000002414 142.0
HFD1_k127_6367484_6 metallopeptidase activity K03630 - - 0.000000000000000000000000000000000008365 139.0
HFD1_k127_6367484_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000006961 138.0
HFD1_k127_6367484_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000001077 109.0
HFD1_k127_6367484_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000002808 87.0
HFD1_k127_6555150_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.926e-287 894.0
HFD1_k127_6555150_1 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 531.0
HFD1_k127_6555150_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000363 218.0
HFD1_k127_6555150_11 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000003289 131.0
HFD1_k127_6555150_12 PFAM UspA domain protein - - - 0.0000000000000000000001566 104.0
HFD1_k127_6555150_13 calcium ion homeostasis - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - 0.00000005612 64.0
HFD1_k127_6555150_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 493.0
HFD1_k127_6555150_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 401.0
HFD1_k127_6555150_4 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 359.0
HFD1_k127_6555150_5 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 375.0
HFD1_k127_6555150_6 PFAM outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 351.0
HFD1_k127_6555150_7 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009477 291.0
HFD1_k127_6555150_8 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002155 286.0
HFD1_k127_6555150_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000009322 241.0
HFD1_k127_6594782_0 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 556.0
HFD1_k127_6594782_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 364.0
HFD1_k127_6594782_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 343.0
HFD1_k127_6594782_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 344.0
HFD1_k127_6594782_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 288.0
HFD1_k127_6594782_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009247 254.0
HFD1_k127_6594782_6 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000006874 217.0
HFD1_k127_6594782_7 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000000000000000000000000000001038 158.0
HFD1_k127_6594782_8 Metallo-beta-lactamase superfamily - - - 0.00000000002194 72.0
HFD1_k127_6594782_9 Metallo-beta-lactamase superfamily - - - 0.00004046 47.0
HFD1_k127_6602818_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 8.881e-220 704.0
HFD1_k127_6602818_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 531.0
HFD1_k127_6602818_10 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000002787 175.0
HFD1_k127_6602818_11 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000723 171.0
HFD1_k127_6602818_12 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000842 138.0
HFD1_k127_6602818_13 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000000000001233 129.0
HFD1_k127_6602818_14 PFAM Uncharacterised protein family UPF0150 - - - 0.00007977 49.0
HFD1_k127_6602818_2 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 441.0
HFD1_k127_6602818_3 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 344.0
HFD1_k127_6602818_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003179 279.0
HFD1_k127_6602818_5 Domains HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004762 254.0
HFD1_k127_6602818_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000002451 231.0
HFD1_k127_6602818_7 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000004713 207.0
HFD1_k127_6602818_8 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000006562 214.0
HFD1_k127_6602818_9 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000003827 209.0
HFD1_k127_6605763_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1022.0
HFD1_k127_6605763_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 595.0
HFD1_k127_6605763_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000001045 114.0
HFD1_k127_6605763_11 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000154 112.0
HFD1_k127_6605763_12 TonB C terminal K03832 - - 0.00000000000000007856 91.0
HFD1_k127_6605763_14 saccharopine dehydrogenase activity - - - 0.00003211 55.0
HFD1_k127_6605763_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 594.0
HFD1_k127_6605763_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 596.0
HFD1_k127_6605763_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 308.0
HFD1_k127_6605763_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001198 270.0
HFD1_k127_6605763_6 PFAM Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000004519 241.0
HFD1_k127_6605763_7 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000009345 204.0
HFD1_k127_6605763_8 Universal stress protein K06149 - - 0.00000000000000000000000000000000001206 142.0
HFD1_k127_6605763_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000004168 126.0
HFD1_k127_6633567_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 463.0
HFD1_k127_6633567_1 antibiotic biosynthetic process K01434,K07116 - 3.5.1.11,3.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 403.0
HFD1_k127_6633567_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000003229 207.0
HFD1_k127_6643710_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 436.0
HFD1_k127_6643710_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 458.0
HFD1_k127_6643710_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 334.0
HFD1_k127_6643710_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000535 171.0
HFD1_k127_6643710_4 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000001001 136.0
HFD1_k127_6643710_5 CoA-binding protein K06929 - - 0.00000000000000000000000000000002802 128.0
HFD1_k127_6769444_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1552.0
HFD1_k127_6769444_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 3.12e-219 689.0
HFD1_k127_6769444_10 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000000000001289 136.0
HFD1_k127_6769444_11 protein with SCP PR1 domains - - - 0.0000000000000000000000000000003318 130.0
HFD1_k127_6769444_12 Thioesterase superfamily K02614 - - 0.00000000002955 70.0
HFD1_k127_6769444_13 LTXXQ motif family protein - - - 0.000000002573 64.0
HFD1_k127_6769444_14 - - - - 0.000009288 53.0
HFD1_k127_6769444_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 581.0
HFD1_k127_6769444_3 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 457.0
HFD1_k127_6769444_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 451.0
HFD1_k127_6769444_5 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 334.0
HFD1_k127_6769444_6 Transcriptional regulator K18136 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000002864 226.0
HFD1_k127_6769444_7 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.000000000000000000000000000000000000000000000003751 199.0
HFD1_k127_6769444_8 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000008713 175.0
HFD1_k127_6769444_9 GYD domain - - - 0.0000000000000000000000000000000005805 134.0
HFD1_k127_6888963_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1375.0
HFD1_k127_6888963_1 Peptidase family M1 domain - - - 4.091e-209 674.0
HFD1_k127_6888963_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000004856 145.0
HFD1_k127_6888963_11 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000007629 106.0
HFD1_k127_6888963_2 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 389.0
HFD1_k127_6888963_3 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 321.0
HFD1_k127_6888963_4 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 318.0
HFD1_k127_6888963_5 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 310.0
HFD1_k127_6888963_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003305 266.0
HFD1_k127_6888963_7 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000000000003156 241.0
HFD1_k127_6888963_8 - - - - 0.0000000000000000000000000000000000000000002568 166.0
HFD1_k127_6888963_9 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000003679 144.0
HFD1_k127_6999977_0 elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 425.0
HFD1_k127_6999977_1 Domain of unknown function (DUF4118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000277 260.0
HFD1_k127_6999977_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000002444 186.0
HFD1_k127_6999977_3 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000001498 170.0
HFD1_k127_6999977_4 Smr domain - - - 0.00000000000000000000000000003246 119.0
HFD1_k127_6999977_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000009214 92.0
HFD1_k127_7041995_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 308.0
HFD1_k127_7041995_1 SMART Elongator protein 3 MiaB NifB K07139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005063 274.0
HFD1_k127_7041995_2 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000001307 214.0
HFD1_k127_7041995_3 Amino acid permease - - - 0.000000000000000000000000000000000000003606 151.0
HFD1_k127_7041995_4 Thioesterase superfamily - - - 0.000000000000000000000000000002217 128.0
HFD1_k127_7041995_5 Papain-like cysteine protease AvrRpt2 - - - 0.000000000000000000000002833 115.0
HFD1_k127_7041995_6 Tetratricopeptide repeat - - - 0.00000000000000000001069 105.0
HFD1_k127_7041995_7 - - - - 0.00000000000002685 84.0
HFD1_k127_7062916_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.143e-236 743.0
HFD1_k127_7062916_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.036e-204 644.0
HFD1_k127_7062916_2 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 465.0
HFD1_k127_7062916_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 461.0
HFD1_k127_7062916_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 334.0
HFD1_k127_7062916_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001299 270.0
HFD1_k127_7062916_6 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000009738 215.0
HFD1_k127_7062916_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000003786 192.0
HFD1_k127_7075726_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 469.0
HFD1_k127_7075726_1 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 445.0
HFD1_k127_7075726_2 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 393.0
HFD1_k127_7075726_3 Ferredoxin--NADP reductase K21567 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 311.0
HFD1_k127_7075726_4 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000002994 240.0
HFD1_k127_7075726_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000173 172.0
HFD1_k127_7075726_6 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000002064 166.0
HFD1_k127_7075726_7 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000002497 160.0
HFD1_k127_7095527_0 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 590.0
HFD1_k127_7095527_1 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 562.0
HFD1_k127_7095527_10 domain, Protein - - - 0.000000000000000000000000000003743 137.0
HFD1_k127_7095527_11 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000008645 104.0
HFD1_k127_7095527_12 - - - - 0.0000000878 56.0
HFD1_k127_7095527_13 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000001833 53.0
HFD1_k127_7095527_14 - - - - 0.0004291 51.0
HFD1_k127_7095527_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 492.0
HFD1_k127_7095527_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 414.0
HFD1_k127_7095527_4 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 399.0
HFD1_k127_7095527_5 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 338.0
HFD1_k127_7095527_6 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 314.0
HFD1_k127_7095527_7 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 312.0
HFD1_k127_7095527_8 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 287.0
HFD1_k127_7095527_9 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000012 190.0
HFD1_k127_7109102_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 575.0
HFD1_k127_7109102_1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 497.0
HFD1_k127_7109102_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 369.0
HFD1_k127_7109102_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 325.0
HFD1_k127_7109102_4 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 321.0
HFD1_k127_7109102_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000009411 241.0
HFD1_k127_7109102_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000001794 212.0
HFD1_k127_7109102_7 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000001323 200.0
HFD1_k127_7123082_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 584.0
HFD1_k127_7123082_1 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
HFD1_k127_7123082_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000002809 226.0
HFD1_k127_7123082_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000004418 168.0
HFD1_k127_7123082_4 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000001619 169.0
HFD1_k127_7123082_5 denitrification pathway - - - 0.000003514 54.0
HFD1_k127_7156221_0 Collagenase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001168 278.0
HFD1_k127_7156221_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005073 256.0
HFD1_k127_7156221_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000003766 205.0
HFD1_k127_7156221_3 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000008132 120.0
HFD1_k127_7156221_4 Glutaredoxin K03676 - - 0.0000002439 53.0
HFD1_k127_7156221_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00003191 53.0
HFD1_k127_717003_0 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 551.0
HFD1_k127_717003_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 336.0
HFD1_k127_717003_10 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000003916 147.0
HFD1_k127_717003_11 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000002139 137.0
HFD1_k127_717003_12 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000001211 108.0
HFD1_k127_717003_13 TonB C terminal K03832 - - 0.000000001461 70.0
HFD1_k127_717003_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 329.0
HFD1_k127_717003_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000241 296.0
HFD1_k127_717003_4 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001266 283.0
HFD1_k127_717003_5 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001966 258.0
HFD1_k127_717003_6 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000006307 198.0
HFD1_k127_717003_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000002101 174.0
HFD1_k127_717003_8 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000002267 153.0
HFD1_k127_717003_9 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000000008559 154.0
HFD1_k127_7281750_0 FtsX-like permease family K02004 - - 2.287e-262 831.0
HFD1_k127_7281750_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 3.945e-221 712.0
HFD1_k127_7281750_10 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 316.0
HFD1_k127_7281750_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 327.0
HFD1_k127_7281750_12 PFAM ABC transporter related K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 318.0
HFD1_k127_7281750_13 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 300.0
HFD1_k127_7281750_14 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000001075 188.0
HFD1_k127_7281750_15 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000004803 112.0
HFD1_k127_7281750_16 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000001946 102.0
HFD1_k127_7281750_2 ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 508.0
HFD1_k127_7281750_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 426.0
HFD1_k127_7281750_4 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 410.0
HFD1_k127_7281750_5 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 425.0
HFD1_k127_7281750_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 386.0
HFD1_k127_7281750_7 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 382.0
HFD1_k127_7281750_8 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 349.0
HFD1_k127_7281750_9 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 341.0
HFD1_k127_7335810_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 554.0
HFD1_k127_7335810_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 430.0
HFD1_k127_7335810_10 ThiS family K03154 - - 0.0000000000132 73.0
HFD1_k127_7335810_11 PFAM Colicin V production protein K03558 - - 0.000008486 56.0
HFD1_k127_7335810_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 394.0
HFD1_k127_7335810_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 401.0
HFD1_k127_7335810_4 Iron-only hydrogenase maturation rSAM protein HydG K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 394.0
HFD1_k127_7335810_5 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
HFD1_k127_7335810_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009688 285.0
HFD1_k127_7335810_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000001259 213.0
HFD1_k127_7335810_8 - - - - 0.0000000000000000000000000000000000000000000000000009238 196.0
HFD1_k127_7335810_9 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000001155 92.0
HFD1_k127_7342190_0 TIGRFAM iron-sulfur cluster binding protein K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 417.0
HFD1_k127_7342190_1 Phosphoadenosine phosphosulfate reductase family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 322.0
HFD1_k127_7342190_2 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 316.0
HFD1_k127_7342190_3 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001501 270.0
HFD1_k127_7342190_4 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000001647 252.0
HFD1_k127_7342190_6 LUD domain K00782 - - 0.00000000000002105 87.0
HFD1_k127_7342190_7 thiamine diphosphate biosynthetic process K03154 - - 0.000000000003325 68.0
HFD1_k127_7342190_9 - - - - 0.000001193 59.0
HFD1_k127_7352508_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1086.0
HFD1_k127_7352508_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 569.0
HFD1_k127_7352508_10 Lipopolysaccharide-assembly - - - 0.0000004811 63.0
HFD1_k127_7352508_11 DNA-binding protein K02340 - 2.7.7.7 0.000006546 59.0
HFD1_k127_7352508_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 310.0
HFD1_k127_7352508_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004128 271.0
HFD1_k127_7352508_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000134 207.0
HFD1_k127_7352508_5 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000001162 208.0
HFD1_k127_7352508_6 ATP cone domain K07738 - - 0.00000000000000000000000000003367 119.0
HFD1_k127_7352508_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000004271 122.0
HFD1_k127_7352508_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000006804 100.0
HFD1_k127_7352508_9 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000001987 65.0
HFD1_k127_7363035_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 364.0
HFD1_k127_7363035_1 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 316.0
HFD1_k127_7363035_2 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 299.0
HFD1_k127_7363035_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000008992 114.0
HFD1_k127_7363035_4 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000001398 106.0
HFD1_k127_7401079_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 6.231e-218 689.0
HFD1_k127_7401079_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 425.0
HFD1_k127_7401079_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 380.0
HFD1_k127_7401079_3 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 370.0
HFD1_k127_7401079_4 LexA DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006235 265.0
HFD1_k127_7401079_5 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001903 244.0
HFD1_k127_7401079_6 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000008253 231.0
HFD1_k127_7401079_7 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000000000000000000000000000000000000000000000005249 192.0
HFD1_k127_7410680_0 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 401.0
HFD1_k127_7410680_1 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 360.0
HFD1_k127_7410680_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 355.0
HFD1_k127_7410680_3 acyl-coa dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000003063 190.0
HFD1_k127_7410680_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000002497 79.0
HFD1_k127_7438589_0 CBS domain containing protein K00974 - 2.7.7.72 1.672e-265 844.0
HFD1_k127_7438589_1 TIGRFAM Tyrosine recombinase XerD K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007811 280.0
HFD1_k127_7438589_2 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000002234 203.0
HFD1_k127_7438589_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000326 172.0
HFD1_k127_7438589_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000005187 126.0
HFD1_k127_7438589_5 YbaK prolyl-tRNA synthetase associated K19055 - - 0.00000000000000000001896 99.0
HFD1_k127_7526915_0 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000005358 252.0
HFD1_k127_7526915_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000009076 237.0
HFD1_k127_7526915_2 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000002266 209.0
HFD1_k127_7526915_3 - - - - 0.000000000000000000000000000000000000000000004364 184.0
HFD1_k127_7526915_4 peroxiredoxin activity - - - 0.000000001829 69.0
HFD1_k127_7550403_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.274e-253 806.0
HFD1_k127_7550403_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 439.0
HFD1_k127_7550403_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000005762 246.0
HFD1_k127_7550403_3 LysM domain - - - 0.000000000000000000000000000947 126.0
HFD1_k127_7550403_4 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000000000000000000000002656 112.0
HFD1_k127_7574767_0 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 425.0
HFD1_k127_7574767_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 370.0
HFD1_k127_7574767_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000108 255.0
HFD1_k127_7574767_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000001785 133.0
HFD1_k127_7574767_4 Pilus assembly protein, PilP K02665 - - 0.0000000000000003995 83.0
HFD1_k127_7579537_0 Putative NAD(P)-binding K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004145 276.0
HFD1_k127_7579537_1 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 255.0
HFD1_k127_7579537_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002164 272.0
HFD1_k127_7579537_3 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000008128 105.0
HFD1_k127_7579537_4 Forkhead associated domain - - - 0.00000000000004377 83.0
HFD1_k127_7579537_5 HEAT repeat - - - 0.000002154 60.0
HFD1_k127_7579537_6 COG0457 FOG TPR repeat - - - 0.000007381 59.0
HFD1_k127_7582756_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 591.0
HFD1_k127_7582756_1 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 575.0
HFD1_k127_7582756_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 512.0
HFD1_k127_7582756_3 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.00000000000000000000000000001109 131.0
HFD1_k127_7582756_4 PTS system sorbose-specific iic component K02795 - - 0.0000000000000000000000939 106.0
HFD1_k127_7582756_5 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000001411 101.0
HFD1_k127_7582756_6 pts system K02745,K02794 - 2.7.1.191 0.000000001079 63.0
HFD1_k127_7612453_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 551.0
HFD1_k127_7612453_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 425.0
HFD1_k127_7717034_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 6.623e-296 937.0
HFD1_k127_7717034_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 550.0
HFD1_k127_7717034_10 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000000000007552 68.0
HFD1_k127_7717034_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 537.0
HFD1_k127_7717034_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 445.0
HFD1_k127_7717034_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 344.0
HFD1_k127_7717034_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 286.0
HFD1_k127_7717034_6 Glycosyl transferase group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000004966 198.0
HFD1_k127_7717034_7 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000000000000000000000000000000000000000000000005821 177.0
HFD1_k127_7717034_8 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000004507 152.0
HFD1_k127_7717034_9 - - - - 0.0000000000006958 75.0
HFD1_k127_7738462_0 Elongation factor Tu domain 2 K02355 - - 1.723e-236 751.0
HFD1_k127_7738462_1 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 420.0
HFD1_k127_7738462_10 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000003521 208.0
HFD1_k127_7738462_11 Transcriptional regulator, CarD family K07736 - - 0.000000000000000000000000000000000000000000000000000007826 194.0
HFD1_k127_7738462_12 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000001561 193.0
HFD1_k127_7738462_13 molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000004426 177.0
HFD1_k127_7738462_14 - - - - 0.000000000000000000001114 111.0
HFD1_k127_7738462_15 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000001186 71.0
HFD1_k127_7738462_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 343.0
HFD1_k127_7738462_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 327.0
HFD1_k127_7738462_4 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 338.0
HFD1_k127_7738462_5 PFAM asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 291.0
HFD1_k127_7738462_6 ThiF family K03148,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000002262 287.0
HFD1_k127_7738462_7 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008653 277.0
HFD1_k127_7738462_8 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002013 252.0
HFD1_k127_7738462_9 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000004256 247.0
HFD1_k127_7753169_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 470.0
HFD1_k127_7753169_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 431.0
HFD1_k127_7753169_10 Essential cell division protein K03589 - - 0.000000000000000000000000000002256 130.0
HFD1_k127_7753169_11 YGGT family K02221 - - 0.000000000000000000000000002701 114.0
HFD1_k127_7753169_12 Belongs to the UPF0235 family K09131 - - 0.0000000000000000005074 94.0
HFD1_k127_7753169_13 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000001256 75.0
HFD1_k127_7753169_14 energy transducer activity K03832 - - 0.000000001158 68.0
HFD1_k127_7753169_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 431.0
HFD1_k127_7753169_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 391.0
HFD1_k127_7753169_4 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000338 258.0
HFD1_k127_7753169_5 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000001151 248.0
HFD1_k127_7753169_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000001068 214.0
HFD1_k127_7753169_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000004943 209.0
HFD1_k127_7753169_8 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000006698 161.0
HFD1_k127_7753169_9 PFAM Maf family protein K06287 - - 0.000000000000000000000000000000000000000001231 164.0
HFD1_k127_7771039_0 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 411.0
HFD1_k127_7771039_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 295.0
HFD1_k127_7771039_2 Guanylyl transferase CofC like K09931 - - 0.0000000000000000000000000000006796 142.0
HFD1_k127_7771039_3 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000003905 137.0
HFD1_k127_7835663_0 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 484.0
HFD1_k127_7835663_1 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 426.0
HFD1_k127_7835663_10 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000372 176.0
HFD1_k127_7835663_2 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 385.0
HFD1_k127_7835663_3 Belongs to the pseudouridine synthase RluA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 357.0
HFD1_k127_7835663_4 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 323.0
HFD1_k127_7835663_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006206 282.0
HFD1_k127_7835663_6 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000005646 258.0
HFD1_k127_7835663_7 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000001479 231.0
HFD1_k127_7835663_8 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000004082 211.0
HFD1_k127_7835663_9 Putative molybdenum carrier - - - 0.000000000000000000000000000000000000000000000000001679 187.0
HFD1_k127_7863076_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 571.0
HFD1_k127_7863076_1 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 541.0
HFD1_k127_7863076_10 Fibronectin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002383 256.0
HFD1_k127_7863076_11 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000001249 204.0
HFD1_k127_7863076_12 CheY-like receiver, AAA-type ATPase and DNA-binding domain-containing response regulator - - - 0.00000000000000000000000000000000000000000000000000009376 202.0
HFD1_k127_7863076_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000007161 172.0
HFD1_k127_7863076_14 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000003224 166.0
HFD1_k127_7863076_15 MFS_1 like family - - - 0.000000000000000000000001565 119.0
HFD1_k127_7863076_16 CorA-like Mg2+ transporter protein - - - 0.0000000000000000000001166 102.0
HFD1_k127_7863076_17 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000008251 103.0
HFD1_k127_7863076_18 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.0000000000000000000008251 103.0
HFD1_k127_7863076_19 PFAM Roadblock LC7 family protein K07131 GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 - 0.00000000000004876 84.0
HFD1_k127_7863076_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 461.0
HFD1_k127_7863076_22 Putative regulatory protein - - - 0.000000007267 59.0
HFD1_k127_7863076_23 PFAM glutaredoxin K18917 - 1.20.4.3 0.0000007319 61.0
HFD1_k127_7863076_24 - - - - 0.000001624 53.0
HFD1_k127_7863076_25 the cation diffusion facilitator (CDF) - - - 0.000003815 50.0
HFD1_k127_7863076_26 Pfam:DUF1049 - - - 0.00004506 51.0
HFD1_k127_7863076_27 - - - - 0.00009149 54.0
HFD1_k127_7863076_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 424.0
HFD1_k127_7863076_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 361.0
HFD1_k127_7863076_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 355.0
HFD1_k127_7863076_6 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 321.0
HFD1_k127_7863076_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000126 303.0
HFD1_k127_7863076_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 260.0
HFD1_k127_7863076_9 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005822 262.0
HFD1_k127_803158_0 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004304 266.0
HFD1_k127_803158_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000003818 218.0
HFD1_k127_803158_2 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000001709 213.0
HFD1_k127_803158_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000207 181.0
HFD1_k127_803158_4 - - - - 0.0000001708 56.0
HFD1_k127_803158_5 anaerobic respiration - - - 0.000005224 55.0
HFD1_k127_820246_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 353.0
HFD1_k127_820246_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 322.0
HFD1_k127_820246_2 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000000000000000000000000000000000000000000004871 198.0
HFD1_k127_820246_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000002675 156.0
HFD1_k127_820246_4 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000001511 151.0
HFD1_k127_820246_5 Cbs domain K04767 - - 0.0000000000000000000006997 112.0
HFD1_k127_857561_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 552.0
HFD1_k127_857561_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 384.0
HFD1_k127_857561_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 362.0
HFD1_k127_857561_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 325.0
HFD1_k127_857561_4 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001383 284.0
HFD1_k127_857561_5 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002933 267.0
HFD1_k127_857561_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000003454 106.0
HFD1_k127_857561_7 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000003811 98.0
HFD1_k127_857561_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000002296 93.0
HFD1_k127_857561_9 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000001769 77.0
HFD1_k127_892490_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 387.0
HFD1_k127_892490_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 347.0
HFD1_k127_892490_2 uridine phosphorylase activity K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 328.0
HFD1_k127_892490_3 Belongs to the enoyl-CoA hydratase isomerase family K01715,K13766 - 4.2.1.17,4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 302.0
HFD1_k127_892490_4 PFAM regulatory protein TetR K16137 - - 0.0000000000000000000000000000000000000000000000000000000000009905 223.0
HFD1_k127_892490_5 - - - - 0.000000000000000000000000000000000000000000000000000000000002396 211.0
HFD1_k127_892490_6 Thioesterase K07107,K12500 - - 0.0000000000000000000000000000000000000000000000000000004644 208.0
HFD1_k127_892490_7 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000002832 120.0
HFD1_k127_892490_8 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000006725 73.0
HFD1_k127_892490_9 - - - - 0.00000004086 60.0
HFD1_k127_900464_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.0 1081.0
HFD1_k127_900464_1 FecR protein - - - 4.264e-293 934.0
HFD1_k127_900464_10 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000001019 192.0
HFD1_k127_900464_11 PFAM General secretion pathway protein K K02460 - - 0.000000000000000000000000000000001125 148.0
HFD1_k127_900464_12 TM2 domain - - - 0.00000000000000000000000000164 118.0
HFD1_k127_900464_14 Type II secretion system (T2SS), protein J K02459 - - 0.000000000000001968 89.0
HFD1_k127_900464_15 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000004912 76.0
HFD1_k127_900464_2 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 587.0
HFD1_k127_900464_3 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 560.0
HFD1_k127_900464_4 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 563.0
HFD1_k127_900464_5 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 554.0
HFD1_k127_900464_6 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 459.0
HFD1_k127_900464_7 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 296.0
HFD1_k127_900464_8 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 296.0
HFD1_k127_900464_9 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000001223 190.0
HFD1_k127_929829_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 537.0
HFD1_k127_929829_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 400.0
HFD1_k127_929829_2 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001183 281.0
HFD1_k127_929829_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000004887 161.0
HFD1_k127_929829_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000001872 146.0
HFD1_k127_929829_5 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000005805 126.0
HFD1_k127_929829_6 Rubrerythrin - - - 0.000000000000000001973 97.0
HFD1_k127_929829_7 Rubrerythrin - - - 0.00000000009155 68.0
HFD1_k127_929829_8 Rubrerythrin - - - 0.000000003574 69.0
HFD1_k127_929829_9 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000001116 53.0
HFD1_k127_935206_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007581 263.0
HFD1_k127_935206_1 Belongs to the peptidase M24B family K01262,K01271 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000006212 247.0
HFD1_k127_935206_2 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000004332 241.0
HFD1_k127_935206_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000002009 161.0
HFD1_k127_935206_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000001126 139.0
HFD1_k127_935206_5 Roadblock/LC7 domain - - - 0.0000000003885 65.0