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Overview

ID MAG01610
Name HFD1_bin.17
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family Gp7-AA6
Genus JAWOLE01
Species
Assembly information
Completeness (%) 93.05
Contamination (%) 0.15
GC content (%) 67.0
N50 (bp) 44,975
Genome size (bp) 4,454,106

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3576

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1013529_0 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 391.0
HFD1_k127_1013529_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 299.0
HFD1_k127_1013529_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000002074 185.0
HFD1_k127_1014150_0 PHP domain protein K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 535.0
HFD1_k127_1014150_1 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 403.0
HFD1_k127_1014150_10 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000001113 196.0
HFD1_k127_1014150_11 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000004271 181.0
HFD1_k127_1014150_12 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000002078 96.0
HFD1_k127_1014150_13 Bacterial regulatory proteins, tetR family - - - 0.0000004142 59.0
HFD1_k127_1014150_15 Protein of unknown function with HXXEE motif - - - 0.00007303 52.0
HFD1_k127_1014150_2 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 344.0
HFD1_k127_1014150_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002109 297.0
HFD1_k127_1014150_4 ABC transporter, permease protein K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001566 265.0
HFD1_k127_1014150_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001977 259.0
HFD1_k127_1014150_6 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000004182 252.0
HFD1_k127_1014150_7 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000007083 234.0
HFD1_k127_1014150_8 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000009841 199.0
HFD1_k127_1014150_9 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000006442 209.0
HFD1_k127_1064087_0 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 325.0
HFD1_k127_1064087_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 304.0
HFD1_k127_1064087_2 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000664 273.0
HFD1_k127_1064087_3 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000004293 206.0
HFD1_k127_1064087_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000002352 203.0
HFD1_k127_1064087_5 phosphorelay signal transduction system - - - 0.0000000000000000000001376 107.0
HFD1_k127_1064087_6 type I secretion outer membrane protein, TolC K12543 - - 0.00002405 54.0
HFD1_k127_1087703_0 Amidohydrolase family - - - 0.0 1443.0
HFD1_k127_1087703_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1165.0
HFD1_k127_1087703_10 Belongs to the FPG family K05522,K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000005276 249.0
HFD1_k127_1087703_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
HFD1_k127_1087703_12 - - - - 0.0000000000000000000000000000000000000000000000000000001414 210.0
HFD1_k127_1087703_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000003021 186.0
HFD1_k127_1087703_14 - - - - 0.000000000000000000000000000000000000005109 160.0
HFD1_k127_1087703_15 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000009544 155.0
HFD1_k127_1087703_16 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000008948 137.0
HFD1_k127_1087703_17 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000002591 124.0
HFD1_k127_1087703_18 Domain of unknown function (DUF4142) K08995 - - 0.0000000000005623 77.0
HFD1_k127_1087703_19 LytTr DNA-binding domain K02477 - - 0.0000000002739 66.0
HFD1_k127_1087703_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 3.267e-256 801.0
HFD1_k127_1087703_20 metalloendopeptidase activity - - - 0.0000000554 64.0
HFD1_k127_1087703_21 polysaccharide deacetylase - - - 0.00000006276 66.0
HFD1_k127_1087703_22 Belongs to the UPF0312 family - - - 0.0000002389 62.0
HFD1_k127_1087703_23 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0007204 44.0
HFD1_k127_1087703_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.445e-223 702.0
HFD1_k127_1087703_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 1.519e-213 677.0
HFD1_k127_1087703_5 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 606.0
HFD1_k127_1087703_6 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 595.0
HFD1_k127_1087703_7 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 436.0
HFD1_k127_1087703_8 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 445.0
HFD1_k127_1087703_9 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000408 289.0
HFD1_k127_110380_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 516.0
HFD1_k127_110380_1 Beta/gamma crystallins - - - 0.00000000000000000001162 96.0
HFD1_k127_1104507_0 Spermine/spermidine synthase domain - - - 7.113e-310 983.0
HFD1_k127_1104507_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 625.0
HFD1_k127_1104507_10 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 372.0
HFD1_k127_1104507_11 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 350.0
HFD1_k127_1104507_12 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 352.0
HFD1_k127_1104507_13 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 331.0
HFD1_k127_1104507_14 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 314.0
HFD1_k127_1104507_15 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 316.0
HFD1_k127_1104507_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 321.0
HFD1_k127_1104507_17 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 306.0
HFD1_k127_1104507_18 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 306.0
HFD1_k127_1104507_19 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 314.0
HFD1_k127_1104507_2 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 599.0
HFD1_k127_1104507_20 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002633 278.0
HFD1_k127_1104507_21 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002689 287.0
HFD1_k127_1104507_22 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000001551 279.0
HFD1_k127_1104507_23 surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002272 286.0
HFD1_k127_1104507_24 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000005134 257.0
HFD1_k127_1104507_25 Psort location Cytoplasmic, score K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000004045 245.0
HFD1_k127_1104507_26 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000008288 243.0
HFD1_k127_1104507_27 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.000000000000000000000000000000000000000000000000000000000000000001282 233.0
HFD1_k127_1104507_28 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000001738 231.0
HFD1_k127_1104507_29 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000002685 253.0
HFD1_k127_1104507_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 574.0
HFD1_k127_1104507_30 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000003256 228.0
HFD1_k127_1104507_31 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000007183 198.0
HFD1_k127_1104507_32 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000002829 193.0
HFD1_k127_1104507_33 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000002434 183.0
HFD1_k127_1104507_34 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000001267 180.0
HFD1_k127_1104507_35 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000002464 173.0
HFD1_k127_1104507_36 PRC-barrel domain - - - 0.000000000000000000000000000000000000000000006665 169.0
HFD1_k127_1104507_37 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000001015 165.0
HFD1_k127_1104507_38 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000001223 171.0
HFD1_k127_1104507_39 Penicillinase repressor - - - 0.00000000000000000000000000000000000000002618 158.0
HFD1_k127_1104507_4 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 543.0
HFD1_k127_1104507_40 Peptidase M56 - - - 0.0000000000000000000000000000000000000001703 172.0
HFD1_k127_1104507_41 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000006398 167.0
HFD1_k127_1104507_42 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.00000000000000000000000000000000007246 142.0
HFD1_k127_1104507_43 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000002211 137.0
HFD1_k127_1104507_44 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000007833 139.0
HFD1_k127_1104507_46 O-Antigen ligase K18814 - - 0.0000000000000000000000000002789 129.0
HFD1_k127_1104507_47 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000005586 124.0
HFD1_k127_1104507_48 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000271 106.0
HFD1_k127_1104507_49 hyperosmotic response - - - 0.0000000000000000000000009512 111.0
HFD1_k127_1104507_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 499.0
HFD1_k127_1104507_50 efflux transmembrane transporter activity - - - 0.000000000000000002865 89.0
HFD1_k127_1104507_51 Protein kinase domain - - - 0.00000000000000000423 93.0
HFD1_k127_1104507_52 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000008074 72.0
HFD1_k127_1104507_53 Cell division protein ZapA K09888 - - 0.00000000001283 68.0
HFD1_k127_1104507_54 Forkhead associated domain - - - 0.00000000003566 72.0
HFD1_k127_1104507_55 Transcriptional regulatory protein, C terminal - - - 0.000000000295 69.0
HFD1_k127_1104507_56 GDSL-like Lipase/Acylhydrolase family - - - 0.000000001736 71.0
HFD1_k127_1104507_57 Rhodanese domain protein - - - 0.00000001747 56.0
HFD1_k127_1104507_59 Involved in the tonB-independent uptake of proteins K01406,K01771,K03641 - 3.4.24.40,4.6.1.13 0.000005234 56.0
HFD1_k127_1104507_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 495.0
HFD1_k127_1104507_60 Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0019344,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 0.000005895 55.0
HFD1_k127_1104507_61 Belongs to the UPF0434 family K09791 - - 0.000006419 57.0
HFD1_k127_1104507_62 efflux transmembrane transporter activity - - - 0.0009153 44.0
HFD1_k127_1104507_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 488.0
HFD1_k127_1104507_8 MFP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 462.0
HFD1_k127_1104507_9 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 450.0
HFD1_k127_111310_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
HFD1_k127_111310_1 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000343 199.0
HFD1_k127_111310_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000006464 158.0
HFD1_k127_111310_3 Putative cyclase - - - 0.0000000000000000000000008939 105.0
HFD1_k127_111310_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000713 68.0
HFD1_k127_111310_5 ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006508,GO:0006605,GO:0006625,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0016043,GO:0016485,GO:0019538,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043574,GO:0044238,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564 3.4.21.53 0.000065 56.0
HFD1_k127_1118574_0 AMP-binding enzyme K01897 - 6.2.1.3 3.212e-220 700.0
HFD1_k127_1118574_1 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 6.385e-220 689.0
HFD1_k127_1118574_10 FAD binding domain - - - 0.000000000000000000000000000000000000000000004724 184.0
HFD1_k127_1118574_11 - - - - 0.00000000000000000000000000000000000000000002106 167.0
HFD1_k127_1118574_12 Protein tyrosine kinase - - - 0.000000000000000000000000000000002233 138.0
HFD1_k127_1118574_13 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000002516 123.0
HFD1_k127_1118574_14 Methyltransferase domain - - - 0.00000003593 63.0
HFD1_k127_1118574_2 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 513.0
HFD1_k127_1118574_3 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 505.0
HFD1_k127_1118574_4 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 424.0
HFD1_k127_1118574_5 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
HFD1_k127_1118574_6 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001641 275.0
HFD1_k127_1118574_7 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001447 269.0
HFD1_k127_1118574_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000008823 263.0
HFD1_k127_1118574_9 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007281 244.0
HFD1_k127_1142947_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.066e-256 822.0
HFD1_k127_1142947_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.835e-243 762.0
HFD1_k127_1142947_10 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 468.0
HFD1_k127_1142947_11 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 460.0
HFD1_k127_1142947_12 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 453.0
HFD1_k127_1142947_13 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 442.0
HFD1_k127_1142947_14 COG0464 ATPases of the AAA class - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 424.0
HFD1_k127_1142947_15 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 420.0
HFD1_k127_1142947_16 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 404.0
HFD1_k127_1142947_17 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 390.0
HFD1_k127_1142947_18 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 378.0
HFD1_k127_1142947_19 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 379.0
HFD1_k127_1142947_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 599.0
HFD1_k127_1142947_20 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 376.0
HFD1_k127_1142947_21 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 379.0
HFD1_k127_1142947_22 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 364.0
HFD1_k127_1142947_23 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 381.0
HFD1_k127_1142947_24 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 362.0
HFD1_k127_1142947_25 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 365.0
HFD1_k127_1142947_26 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 359.0
HFD1_k127_1142947_27 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 322.0
HFD1_k127_1142947_28 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 305.0
HFD1_k127_1142947_29 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 288.0
HFD1_k127_1142947_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 564.0
HFD1_k127_1142947_30 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006197 278.0
HFD1_k127_1142947_31 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000006848 271.0
HFD1_k127_1142947_32 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001874 261.0
HFD1_k127_1142947_33 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002045 263.0
HFD1_k127_1142947_34 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000226 272.0
HFD1_k127_1142947_35 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003966 261.0
HFD1_k127_1142947_36 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000003535 250.0
HFD1_k127_1142947_37 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000004512 235.0
HFD1_k127_1142947_38 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000506 258.0
HFD1_k127_1142947_39 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000003101 246.0
HFD1_k127_1142947_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 523.0
HFD1_k127_1142947_40 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000005702 235.0
HFD1_k127_1142947_41 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000001231 224.0
HFD1_k127_1142947_42 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000001526 223.0
HFD1_k127_1142947_43 sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000005831 235.0
HFD1_k127_1142947_44 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000002746 229.0
HFD1_k127_1142947_45 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000006787 217.0
HFD1_k127_1142947_46 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000001414 213.0
HFD1_k127_1142947_47 CBS domain containing protein K03699 - - 0.0000000000000000000000000000000000000000000000000000000006547 222.0
HFD1_k127_1142947_48 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000838 200.0
HFD1_k127_1142947_49 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000009497 194.0
HFD1_k127_1142947_5 DNA segregation ATPase, FtsK SpoIIIE family K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 531.0
HFD1_k127_1142947_50 Cupin domain - - - 0.0000000000000000000000000000000000000000000000002308 179.0
HFD1_k127_1142947_51 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000159 192.0
HFD1_k127_1142947_52 Subtilase family - - - 0.00000000000000000000000000000000000000000000002053 197.0
HFD1_k127_1142947_53 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000002734 193.0
HFD1_k127_1142947_54 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000008169 172.0
HFD1_k127_1142947_55 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000004641 164.0
HFD1_k127_1142947_56 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000001326 173.0
HFD1_k127_1142947_57 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000039 159.0
HFD1_k127_1142947_58 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000002591 157.0
HFD1_k127_1142947_59 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000008131 144.0
HFD1_k127_1142947_6 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 500.0
HFD1_k127_1142947_60 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000005823 139.0
HFD1_k127_1142947_61 MlaD protein K02067 - - 0.00000000000000000000000000000000001088 151.0
HFD1_k127_1142947_62 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000001918 134.0
HFD1_k127_1142947_63 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000564 134.0
HFD1_k127_1142947_64 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000000000000000004391 117.0
HFD1_k127_1142947_65 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000001487 124.0
HFD1_k127_1142947_66 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000001562 131.0
HFD1_k127_1142947_67 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000002713 112.0
HFD1_k127_1142947_68 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000001356 114.0
HFD1_k127_1142947_69 Domain of unknown function (DUF4340) - - - 0.000000000000000000008188 106.0
HFD1_k127_1142947_7 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 513.0
HFD1_k127_1142947_70 domain, Protein - - - 0.00000000000001158 86.0
HFD1_k127_1142947_71 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.00000000000004108 79.0
HFD1_k127_1142947_72 Protein of unknown function, DUF255 - - - 0.000000000004137 74.0
HFD1_k127_1142947_73 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.0000000002624 66.0
HFD1_k127_1142947_74 Protein of unknown function (DUF1499) - - - 0.00000003955 58.0
HFD1_k127_1142947_75 O-antigen polymerase - - - 0.000004839 60.0
HFD1_k127_1142947_76 oligosaccharyl transferase activity - - - 0.0003221 53.0
HFD1_k127_1142947_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 490.0
HFD1_k127_1142947_9 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 496.0
HFD1_k127_1195404_0 choline dehydrogenase activity - - - 6.182e-278 862.0
HFD1_k127_1195404_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.275e-254 799.0
HFD1_k127_1195404_10 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 419.0
HFD1_k127_1195404_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 346.0
HFD1_k127_1195404_12 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 359.0
HFD1_k127_1195404_13 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 313.0
HFD1_k127_1195404_14 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 287.0
HFD1_k127_1195404_15 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001028 265.0
HFD1_k127_1195404_16 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000161 239.0
HFD1_k127_1195404_17 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000001142 253.0
HFD1_k127_1195404_18 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000003498 220.0
HFD1_k127_1195404_19 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000001232 217.0
HFD1_k127_1195404_2 Amylo-alpha-1,6-glucosidase - - - 2.907e-244 771.0
HFD1_k127_1195404_20 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000003521 211.0
HFD1_k127_1195404_21 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000002424 203.0
HFD1_k127_1195404_22 Sulfate ABC transporter substrate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000001076 188.0
HFD1_k127_1195404_23 sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000001267 186.0
HFD1_k127_1195404_24 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000000000000008211 164.0
HFD1_k127_1195404_25 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000003059 171.0
HFD1_k127_1195404_26 DinB family - - - 0.0000000000000000000000000000000002137 145.0
HFD1_k127_1195404_27 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000007127 138.0
HFD1_k127_1195404_28 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000001305 130.0
HFD1_k127_1195404_29 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 - 2.3.1.179 0.000000000000000000000000000002859 134.0
HFD1_k127_1195404_3 Protein kinase domain K12132 - 2.7.11.1 5.53e-209 679.0
HFD1_k127_1195404_30 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000001431 131.0
HFD1_k127_1195404_31 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000003021 121.0
HFD1_k127_1195404_32 response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000004814 81.0
HFD1_k127_1195404_33 Thioesterase-like superfamily K07107 - - 0.000000000000397 83.0
HFD1_k127_1195404_34 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000003088 76.0
HFD1_k127_1195404_35 Belongs to the 'phage' integrase family - - - 0.0000000001189 67.0
HFD1_k127_1195404_36 PKD domain - - - 0.0000000001582 73.0
HFD1_k127_1195404_37 - - - - 0.0000001398 62.0
HFD1_k127_1195404_38 Putative zinc-finger - - - 0.0000006938 56.0
HFD1_k127_1195404_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.642e-205 659.0
HFD1_k127_1195404_40 - - - - 0.00005441 46.0
HFD1_k127_1195404_41 Forkhead associated domain - - - 0.0005588 52.0
HFD1_k127_1195404_42 YbbR-like protein - - - 0.0005671 52.0
HFD1_k127_1195404_5 GvpD gas vesicle protein K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 541.0
HFD1_k127_1195404_6 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 475.0
HFD1_k127_1195404_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 443.0
HFD1_k127_1195404_8 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 442.0
HFD1_k127_1195404_9 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 459.0
HFD1_k127_1197727_0 Tricorn protease homolog - - - 0.0 1490.0
HFD1_k127_1197727_1 Phosphoesterase family - - - 3.557e-211 689.0
HFD1_k127_1197727_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000001212 229.0
HFD1_k127_1197727_11 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000009286 140.0
HFD1_k127_1197727_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000147 139.0
HFD1_k127_1197727_13 diguanylate cyclase - - - 0.000000000000000000000000000000007731 148.0
HFD1_k127_1197727_14 methylamine metabolic process - - - 0.00000000000000000000000000000004135 135.0
HFD1_k127_1197727_15 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.0000000000000000000000000001155 123.0
HFD1_k127_1197727_16 collagen metabolic process - - - 0.00000000000002376 82.0
HFD1_k127_1197727_17 - - - - 0.0000000036 62.0
HFD1_k127_1197727_2 Insulinase (Peptidase family M16) K07263 - - 2.026e-198 633.0
HFD1_k127_1197727_3 enterobactin catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 556.0
HFD1_k127_1197727_4 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 491.0
HFD1_k127_1197727_5 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 361.0
HFD1_k127_1197727_6 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 355.0
HFD1_k127_1197727_7 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006924 287.0
HFD1_k127_1197727_8 Peptidase family S51 K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006198 276.0
HFD1_k127_1197727_9 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000002227 249.0
HFD1_k127_122763_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 376.0
HFD1_k127_122763_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000001317 123.0
HFD1_k127_122763_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000003842 84.0
HFD1_k127_1356916_0 Psort location CytoplasmicMembrane, score - - - 0.0000000002204 74.0
HFD1_k127_1356916_1 Bacterial membrane protein, YfhO - - - 0.0000000004196 72.0
HFD1_k127_1380187_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 468.0
HFD1_k127_1380187_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 378.0
HFD1_k127_1380187_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 378.0
HFD1_k127_1380187_3 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000003336 182.0
HFD1_k127_1385884_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 8.429e-234 769.0
HFD1_k127_1385884_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 1.066e-225 762.0
HFD1_k127_1385884_2 Tetratricopeptide repeat - - - 5.991e-208 664.0
HFD1_k127_1385884_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 494.0
HFD1_k127_1385884_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 488.0
HFD1_k127_1385884_5 Viral (Superfamily 1) RNA helicase K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 504.0
HFD1_k127_1385884_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 348.0
HFD1_k127_1385884_7 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 331.0
HFD1_k127_1385884_8 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001224 267.0
HFD1_k127_1385884_9 cheY-homologous receiver domain - - - 0.000000000000000000000002399 106.0
HFD1_k127_159904_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 522.0
HFD1_k127_159904_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000004584 166.0
HFD1_k127_159904_2 Peptidase M56 - - - 0.00000000000003793 85.0
HFD1_k127_159904_3 Biotin-requiring enzyme - - - 0.000000000008665 76.0
HFD1_k127_162979_0 OPT oligopeptide transporter protein - - - 2.696e-320 1000.0
HFD1_k127_162979_1 Carboxypeptidase regulatory-like domain - - - 3.094e-314 991.0
HFD1_k127_162979_10 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 556.0
HFD1_k127_162979_11 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 550.0
HFD1_k127_162979_12 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 496.0
HFD1_k127_162979_14 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 456.0
HFD1_k127_162979_15 PFAM Thermolysin metallopeptidase, alpha-helical domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 445.0
HFD1_k127_162979_16 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 447.0
HFD1_k127_162979_17 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 439.0
HFD1_k127_162979_18 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 426.0
HFD1_k127_162979_19 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009436 412.0
HFD1_k127_162979_2 Angiotensin-converting enzyme K01283 - 3.4.15.1 1.443e-304 942.0
HFD1_k127_162979_20 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 392.0
HFD1_k127_162979_21 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 376.0
HFD1_k127_162979_22 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 359.0
HFD1_k127_162979_23 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 349.0
HFD1_k127_162979_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 361.0
HFD1_k127_162979_25 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 329.0
HFD1_k127_162979_26 PFAM alanine racemase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 316.0
HFD1_k127_162979_27 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 254.0
HFD1_k127_162979_28 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000001076 242.0
HFD1_k127_162979_29 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 246.0
HFD1_k127_162979_3 Lamin Tail Domain K07004 - - 4.988e-241 782.0
HFD1_k127_162979_30 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000006963 233.0
HFD1_k127_162979_31 Belongs to the BI1 family K06890,K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000007106 229.0
HFD1_k127_162979_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003962 231.0
HFD1_k127_162979_33 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000009486 216.0
HFD1_k127_162979_34 heme binding K21472 - - 0.0000000000000000000000000000000000000000000000000000000002761 211.0
HFD1_k127_162979_35 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000002809 209.0
HFD1_k127_162979_36 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000001471 190.0
HFD1_k127_162979_37 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001456 185.0
HFD1_k127_162979_38 photosynthesis - - - 0.000000000000000000000000000000000000000000002703 171.0
HFD1_k127_162979_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.259e-199 630.0
HFD1_k127_162979_40 DNA-templated transcription, initiation K03088,K07263 - - 0.0000000000000000000000000000000000000000005436 164.0
HFD1_k127_162979_41 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000001199 152.0
HFD1_k127_162979_42 - - - - 0.0000000000000000000000000000000003789 137.0
HFD1_k127_162979_44 - - - - 0.000000000000000000000000000000001224 137.0
HFD1_k127_162979_45 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000567 123.0
HFD1_k127_162979_47 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000002179 119.0
HFD1_k127_162979_48 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000000003416 106.0
HFD1_k127_162979_49 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000001548 87.0
HFD1_k127_162979_5 protein secretion by the type I secretion system K11085 - - 4.664e-199 639.0
HFD1_k127_162979_50 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.0000000000005289 74.0
HFD1_k127_162979_51 - - - - 0.000000000002456 72.0
HFD1_k127_162979_52 DNA-binding transcription factor activity K18996 - - 0.00000000001201 69.0
HFD1_k127_162979_53 RyR domain - - - 0.0000000007545 60.0
HFD1_k127_162979_54 helix_turn_helix, Lux Regulon - - - 0.0000000009856 69.0
HFD1_k127_162979_55 PFAM blue (type 1) copper domain protein - - - 0.0000002186 59.0
HFD1_k127_162979_56 Ami_3 K01448 - 3.5.1.28 0.00001109 55.0
HFD1_k127_162979_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 636.0
HFD1_k127_162979_7 RNB K01147 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 614.0
HFD1_k127_162979_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 603.0
HFD1_k127_162979_9 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 588.0
HFD1_k127_1636534_0 Fungalysin metallopeptidase (M36) K01417 - - 4.202e-240 762.0
HFD1_k127_1636534_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 432.0
HFD1_k127_1636534_2 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.00000000000000000000000000000000000000005579 163.0
HFD1_k127_1636534_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000002441 58.0
HFD1_k127_1636534_4 Predicted periplasmic lipoprotein (DUF2279) - - - 0.000000292 59.0
HFD1_k127_168266_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000005575 235.0
HFD1_k127_168266_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000002279 184.0
HFD1_k127_168266_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000002732 197.0
HFD1_k127_168266_3 Glycosyl Transferase - - - 0.00000000000000000000000000000000000000155 162.0
HFD1_k127_168266_4 TIGRFAM amino acid adenylation domain - - - 0.00000006497 66.0
HFD1_k127_1704891_0 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 426.0
HFD1_k127_1704891_1 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 347.0
HFD1_k127_1704891_2 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000001499 244.0
HFD1_k127_1704891_3 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000005197 134.0
HFD1_k127_1704891_5 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000004885 66.0
HFD1_k127_1726930_0 Involved in the tonB-independent uptake of proteins - - - 4.352e-197 640.0
HFD1_k127_1726930_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 621.0
HFD1_k127_1780190_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 9.795e-240 751.0
HFD1_k127_1780190_1 PFAM Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 9.466e-208 667.0
HFD1_k127_1780190_10 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 342.0
HFD1_k127_1780190_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 344.0
HFD1_k127_1780190_12 Histidine kinase-like ATPases K01768,K02488,K17763 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 346.0
HFD1_k127_1780190_13 Amidinotransferase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 343.0
HFD1_k127_1780190_14 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 313.0
HFD1_k127_1780190_15 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 306.0
HFD1_k127_1780190_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001079 184.0
HFD1_k127_1780190_17 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000003155 187.0
HFD1_k127_1780190_18 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000002927 151.0
HFD1_k127_1780190_19 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000001702 136.0
HFD1_k127_1780190_2 adenylosuccinate lyase K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 497.0
HFD1_k127_1780190_20 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000003192 137.0
HFD1_k127_1780190_21 - - - - 0.0000000000000000000000044 106.0
HFD1_k127_1780190_22 Ferric siderophore transporter, periplasmic energy transduction protein TonB K03832 - - 0.000000001176 70.0
HFD1_k127_1780190_3 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 403.0
HFD1_k127_1780190_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 406.0
HFD1_k127_1780190_5 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 404.0
HFD1_k127_1780190_6 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 370.0
HFD1_k127_1780190_7 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 359.0
HFD1_k127_1780190_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 354.0
HFD1_k127_1780190_9 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 357.0
HFD1_k127_1798648_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.86e-212 675.0
HFD1_k127_1798648_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 576.0
HFD1_k127_1798648_10 BMC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001534 271.0
HFD1_k127_1798648_11 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 269.0
HFD1_k127_1798648_12 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000002655 246.0
HFD1_k127_1798648_13 deoxyribose-phosphate aldolase activity K00852,K01619,K01840,K01844 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.1.15,4.1.2.4,5.4.2.8,5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000003548 255.0
HFD1_k127_1798648_14 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005655 256.0
HFD1_k127_1798648_15 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000005438 256.0
HFD1_k127_1798648_16 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000002338 236.0
HFD1_k127_1798648_17 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000007349 232.0
HFD1_k127_1798648_18 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000001241 225.0
HFD1_k127_1798648_19 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000006175 214.0
HFD1_k127_1798648_2 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 494.0
HFD1_k127_1798648_20 ATPase activity - - - 0.00000000000000000000000000000000000000000000000009663 198.0
HFD1_k127_1798648_21 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000004496 183.0
HFD1_k127_1798648_22 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000002416 185.0
HFD1_k127_1798648_23 BMC K04027 - - 0.0000000000000000000000000000000000004872 143.0
HFD1_k127_1798648_24 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000002883 136.0
HFD1_k127_1798648_25 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000003916 140.0
HFD1_k127_1798648_26 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000001421 149.0
HFD1_k127_1798648_27 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000153 143.0
HFD1_k127_1798648_28 Pfam:UPF0118 - - - 0.0000000000000000000000000000000004929 148.0
HFD1_k127_1798648_29 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000004956 144.0
HFD1_k127_1798648_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 463.0
HFD1_k127_1798648_30 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000002379 135.0
HFD1_k127_1798648_31 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000714 128.0
HFD1_k127_1798648_32 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000000003384 120.0
HFD1_k127_1798648_33 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000001325 102.0
HFD1_k127_1798648_34 Microcompartments protein - - - 0.0000000000000003818 87.0
HFD1_k127_1798648_35 chlorophyll binding - - - 0.0000000000000004026 91.0
HFD1_k127_1798648_36 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000002018 83.0
HFD1_k127_1798648_37 peptidyl-tyrosine sulfation - - - 0.0000000000000338 81.0
HFD1_k127_1798648_39 SprT-like family - - - 0.0001133 51.0
HFD1_k127_1798648_4 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 356.0
HFD1_k127_1798648_5 L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 342.0
HFD1_k127_1798648_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 319.0
HFD1_k127_1798648_7 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 313.0
HFD1_k127_1798648_8 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 324.0
HFD1_k127_1798648_9 BMC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002375 258.0
HFD1_k127_1820523_0 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 582.0
HFD1_k127_1820523_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 426.0
HFD1_k127_1820523_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000142 293.0
HFD1_k127_1820523_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000747 295.0
HFD1_k127_1820523_4 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000001417 236.0
HFD1_k127_1820523_5 - - - - 0.000000000000000000000006884 108.0
HFD1_k127_1820523_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000521 80.0
HFD1_k127_1829397_0 Heat shock 70 kDa protein K04043 - - 4.319e-301 935.0
HFD1_k127_1829397_1 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 3.018e-248 781.0
HFD1_k127_1829397_10 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 384.0
HFD1_k127_1829397_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 387.0
HFD1_k127_1829397_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 372.0
HFD1_k127_1829397_13 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 356.0
HFD1_k127_1829397_14 succinate dehydrogenase K00240 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 336.0
HFD1_k127_1829397_15 response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 323.0
HFD1_k127_1829397_16 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 329.0
HFD1_k127_1829397_17 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 306.0
HFD1_k127_1829397_18 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002157 274.0
HFD1_k127_1829397_19 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000368 257.0
HFD1_k127_1829397_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.423e-203 647.0
HFD1_k127_1829397_20 PFAM Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000001201 252.0
HFD1_k127_1829397_21 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001876 261.0
HFD1_k127_1829397_22 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000003144 235.0
HFD1_k127_1829397_23 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000004271 232.0
HFD1_k127_1829397_24 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000004786 248.0
HFD1_k127_1829397_25 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.0000000000000000000000000000000000000000000000000000000000001222 224.0
HFD1_k127_1829397_26 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000209 216.0
HFD1_k127_1829397_27 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000001921 214.0
HFD1_k127_1829397_28 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000008452 199.0
HFD1_k127_1829397_29 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000005371 198.0
HFD1_k127_1829397_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 574.0
HFD1_k127_1829397_30 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000001591 177.0
HFD1_k127_1829397_31 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000003211 169.0
HFD1_k127_1829397_32 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000009919 166.0
HFD1_k127_1829397_33 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000001145 161.0
HFD1_k127_1829397_34 Peptidase M23 - - - 0.000000000000000000000000000000002865 143.0
HFD1_k127_1829397_35 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000009958 132.0
HFD1_k127_1829397_36 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000001826 131.0
HFD1_k127_1829397_37 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000003467 143.0
HFD1_k127_1829397_38 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000004271 138.0
HFD1_k127_1829397_39 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000004656 113.0
HFD1_k127_1829397_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 499.0
HFD1_k127_1829397_40 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000456 118.0
HFD1_k127_1829397_41 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000002264 103.0
HFD1_k127_1829397_42 oxidoreductase activity - - - 0.00000000000000000001856 106.0
HFD1_k127_1829397_43 Peptidase M56 - - - 0.0000000000000000438 95.0
HFD1_k127_1829397_44 Peptidase M56 - - - 0.0000000003365 73.0
HFD1_k127_1829397_45 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000002207 71.0
HFD1_k127_1829397_47 COG3209 Rhs family protein - - - 0.000000003109 69.0
HFD1_k127_1829397_48 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000003891 67.0
HFD1_k127_1829397_49 Domain of unknown function (DUF1844) - - - 0.0000001598 59.0
HFD1_k127_1829397_5 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 485.0
HFD1_k127_1829397_50 Domain of unknown function (DUF4388) - - - 0.0000004366 63.0
HFD1_k127_1829397_51 Uncharacterised protein family (UPF0158) - - - 0.000004938 54.0
HFD1_k127_1829397_52 protein kinase activity - - - 0.000007875 59.0
HFD1_k127_1829397_53 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00001312 58.0
HFD1_k127_1829397_54 phosphorelay signal transduction system - - - 0.0005479 52.0
HFD1_k127_1829397_6 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 464.0
HFD1_k127_1829397_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 427.0
HFD1_k127_1829397_8 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 430.0
HFD1_k127_1829397_9 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 404.0
HFD1_k127_1870245_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 3.18e-209 702.0
HFD1_k127_1870245_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 364.0
HFD1_k127_1870245_2 eRF1 domain 3 - - - 0.000000000000000000000000000000000000000000000000000003213 199.0
HFD1_k127_1876623_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1149.0
HFD1_k127_1876623_1 xanthine dehydrogenase activity - - - 2.845e-314 999.0
HFD1_k127_1876623_10 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 438.0
HFD1_k127_1876623_11 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 413.0
HFD1_k127_1876623_12 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 411.0
HFD1_k127_1876623_13 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 404.0
HFD1_k127_1876623_14 allantoinase K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 397.0
HFD1_k127_1876623_15 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 420.0
HFD1_k127_1876623_16 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 400.0
HFD1_k127_1876623_17 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 390.0
HFD1_k127_1876623_18 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 374.0
HFD1_k127_1876623_19 Cardiolipin synthetase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 360.0
HFD1_k127_1876623_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.644e-262 821.0
HFD1_k127_1876623_20 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 344.0
HFD1_k127_1876623_21 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 346.0
HFD1_k127_1876623_22 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 335.0
HFD1_k127_1876623_23 Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 327.0
HFD1_k127_1876623_24 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 292.0
HFD1_k127_1876623_25 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000002334 256.0
HFD1_k127_1876623_26 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000001028 242.0
HFD1_k127_1876623_27 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000002025 242.0
HFD1_k127_1876623_28 PFAM Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000001192 234.0
HFD1_k127_1876623_29 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000001057 214.0
HFD1_k127_1876623_3 PFAM amidohydrolase K01464 - 3.5.2.2 5.515e-195 626.0
HFD1_k127_1876623_30 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000001142 205.0
HFD1_k127_1876623_31 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000137 200.0
HFD1_k127_1876623_32 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000001272 189.0
HFD1_k127_1876623_33 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000886 183.0
HFD1_k127_1876623_34 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000003569 162.0
HFD1_k127_1876623_35 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000003936 177.0
HFD1_k127_1876623_36 WYL domain K13572 - - 0.0000000000000000000000000000000000000001651 165.0
HFD1_k127_1876623_37 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000002601 167.0
HFD1_k127_1876623_38 phosphorelay signal transduction system - - - 0.000000000000000000000000001883 123.0
HFD1_k127_1876623_39 - - - - 0.000000000000000000000000004658 126.0
HFD1_k127_1876623_4 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 586.0
HFD1_k127_1876623_40 cell redox homeostasis - - - 0.0000000000000000000000008694 110.0
HFD1_k127_1876623_41 peptidyl-tyrosine sulfation - - - 0.00000000000000000000006076 110.0
HFD1_k127_1876623_42 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000003565 94.0
HFD1_k127_1876623_43 Family of unknown function (DUF5329) - - - 0.00000000000002779 84.0
HFD1_k127_1876623_44 SnoaL-like domain K07023 - - 0.00000000003478 72.0
HFD1_k127_1876623_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 599.0
HFD1_k127_1876623_6 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 574.0
HFD1_k127_1876623_7 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 520.0
HFD1_k127_1876623_8 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 496.0
HFD1_k127_1876623_9 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 490.0
HFD1_k127_188095_0 Protein kinase domain K12132 - 2.7.11.1 1.219e-242 782.0
HFD1_k127_188095_1 Protein kinase domain K12132 - 2.7.11.1 5.651e-197 645.0
HFD1_k127_188095_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 499.0
HFD1_k127_188095_3 - - - - 0.0000000000000000005408 100.0
HFD1_k127_188095_4 protein kinase activity - - - 0.000000000000004717 78.0
HFD1_k127_188095_5 nucleic acid-binding protein, contains PIN domain - - - 0.000001358 56.0
HFD1_k127_192720_0 AcrB/AcrD/AcrF family - - - 0.0 1117.0
HFD1_k127_192720_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1078.0
HFD1_k127_192720_10 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 583.0
HFD1_k127_192720_11 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 497.0
HFD1_k127_192720_12 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 467.0
HFD1_k127_192720_13 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 461.0
HFD1_k127_192720_14 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 447.0
HFD1_k127_192720_15 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 404.0
HFD1_k127_192720_16 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 411.0
HFD1_k127_192720_17 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 367.0
HFD1_k127_192720_18 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 338.0
HFD1_k127_192720_19 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 319.0
HFD1_k127_192720_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 4.427e-307 952.0
HFD1_k127_192720_20 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 304.0
HFD1_k127_192720_21 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006383 280.0
HFD1_k127_192720_22 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001119 283.0
HFD1_k127_192720_23 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000001098 270.0
HFD1_k127_192720_24 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006822 275.0
HFD1_k127_192720_25 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001317 274.0
HFD1_k127_192720_26 Helix-hairpin-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003215 263.0
HFD1_k127_192720_27 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000007133 207.0
HFD1_k127_192720_28 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000009594 220.0
HFD1_k127_192720_29 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000005266 165.0
HFD1_k127_192720_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.628e-289 910.0
HFD1_k127_192720_30 - - - - 0.000000000000000000000000000000000000001616 154.0
HFD1_k127_192720_31 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.000000000000000000000000000000000000007701 165.0
HFD1_k127_192720_32 Histidine kinase - - - 0.00000000000000000000000000000000000002107 161.0
HFD1_k127_192720_33 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.000000000000000000000000000000000004841 146.0
HFD1_k127_192720_35 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000205 150.0
HFD1_k127_192720_36 - - - - 0.0000000000000000000000000000000005513 134.0
HFD1_k127_192720_37 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000007568 146.0
HFD1_k127_192720_38 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.0000000000000000000000000000005217 127.0
HFD1_k127_192720_39 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000003405 113.0
HFD1_k127_192720_4 AAA domain - - - 6.579e-281 888.0
HFD1_k127_192720_40 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000001314 109.0
HFD1_k127_192720_41 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000003155 106.0
HFD1_k127_192720_42 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000001131 100.0
HFD1_k127_192720_43 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000003117 107.0
HFD1_k127_192720_44 Cbs domain K04767 - - 0.00000000000000000000772 98.0
HFD1_k127_192720_45 Universal stress protein - - - 0.0000000000000000000138 100.0
HFD1_k127_192720_46 - - - - 0.0000000000000000004018 102.0
HFD1_k127_192720_47 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000005288 91.0
HFD1_k127_192720_48 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000001109 93.0
HFD1_k127_192720_49 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 - 2.5.1.74 0.000000000000002268 81.0
HFD1_k127_192720_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.365e-234 750.0
HFD1_k127_192720_50 - - - - 0.000000000000005233 86.0
HFD1_k127_192720_51 Sulfurtransferase - - - 0.000000000000008523 87.0
HFD1_k127_192720_52 hyperosmotic response - - - 0.00000000000001807 87.0
HFD1_k127_192720_54 Outer membrane efflux protein - - - 0.00000003183 66.0
HFD1_k127_192720_55 helix_turn_helix, Lux Regulon - - - 0.00000007945 63.0
HFD1_k127_192720_57 Helix-turn-helix domain - - - 0.00001732 52.0
HFD1_k127_192720_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 8.889e-231 720.0
HFD1_k127_192720_7 Cytochrome c - - - 1.784e-195 617.0
HFD1_k127_192720_8 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 611.0
HFD1_k127_192720_9 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 595.0
HFD1_k127_1947755_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 612.0
HFD1_k127_1947755_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001125 205.0
HFD1_k127_1949113_0 oligopeptide transporter, OPT family - - - 7.719e-219 697.0
HFD1_k127_1949113_1 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 424.0
HFD1_k127_1949113_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000003579 239.0
HFD1_k127_1949113_11 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000001248 224.0
HFD1_k127_1949113_12 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000007243 226.0
HFD1_k127_1949113_13 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000003015 210.0
HFD1_k127_1949113_14 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000004163 207.0
HFD1_k127_1949113_15 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000007295 202.0
HFD1_k127_1949113_16 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000001274 173.0
HFD1_k127_1949113_17 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000009172 173.0
HFD1_k127_1949113_18 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000001238 146.0
HFD1_k127_1949113_19 Uncharacterized protein family UPF0029 - - - 0.000000000000000000000000001256 127.0
HFD1_k127_1949113_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 418.0
HFD1_k127_1949113_20 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000008614 91.0
HFD1_k127_1949113_21 PFAM blue (type 1) copper domain protein - - - 0.000000000000000003736 89.0
HFD1_k127_1949113_22 Haemolytic K08998 - - 0.00000000000000001761 85.0
HFD1_k127_1949113_23 Preprotein translocase SecG subunit K03075 - - 0.0000000000000004969 84.0
HFD1_k127_1949113_24 - - - - 0.000000000003905 72.0
HFD1_k127_1949113_25 - - - - 0.0000000001092 73.0
HFD1_k127_1949113_26 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000003855 59.0
HFD1_k127_1949113_27 Glutaredoxin K03676 - - 0.00000002486 56.0
HFD1_k127_1949113_28 transport - - - 0.000391 51.0
HFD1_k127_1949113_29 Putative adhesin - - - 0.0007705 50.0
HFD1_k127_1949113_3 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 423.0
HFD1_k127_1949113_4 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 338.0
HFD1_k127_1949113_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 302.0
HFD1_k127_1949113_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 306.0
HFD1_k127_1949113_7 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000002834 278.0
HFD1_k127_1949113_8 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002518 265.0
HFD1_k127_196213_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 407.0
HFD1_k127_201817_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 610.0
HFD1_k127_201817_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 429.0
HFD1_k127_201817_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003298 205.0
HFD1_k127_201817_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000005842 193.0
HFD1_k127_201817_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000003312 184.0
HFD1_k127_201817_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000002548 182.0
HFD1_k127_201817_14 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000003421 175.0
HFD1_k127_201817_15 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000006829 175.0
HFD1_k127_201817_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001012 160.0
HFD1_k127_201817_17 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000015 165.0
HFD1_k127_201817_18 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001409 160.0
HFD1_k127_201817_19 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000003892 146.0
HFD1_k127_201817_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 408.0
HFD1_k127_201817_20 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000002258 138.0
HFD1_k127_201817_21 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000003786 138.0
HFD1_k127_201817_22 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000004796 135.0
HFD1_k127_201817_23 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000003104 114.0
HFD1_k127_201817_24 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001263 119.0
HFD1_k127_201817_25 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000004098 110.0
HFD1_k127_201817_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000002669 97.0
HFD1_k127_201817_27 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000004498 89.0
HFD1_k127_201817_28 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000001653 89.0
HFD1_k127_201817_29 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000002566 67.0
HFD1_k127_201817_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 302.0
HFD1_k127_201817_30 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000242 71.0
HFD1_k127_201817_31 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000005668 59.0
HFD1_k127_201817_32 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00002651 54.0
HFD1_k127_201817_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001665 282.0
HFD1_k127_201817_5 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
HFD1_k127_201817_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003408 265.0
HFD1_k127_201817_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007927 243.0
HFD1_k127_201817_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000002083 216.0
HFD1_k127_201817_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000005421 210.0
HFD1_k127_2053753_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 536.0
HFD1_k127_2053753_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 464.0
HFD1_k127_2053753_2 NAD dependent epimerase/dehydratase family K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 443.0
HFD1_k127_2053753_3 - - - - 0.000000000000000000000000000000000000000000000000000002358 211.0
HFD1_k127_2125663_0 ABC transporter, ATP-binding protein K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000575 225.0
HFD1_k127_2125663_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000003574 162.0
HFD1_k127_2352855_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 599.0
HFD1_k127_2352855_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000675 224.0
HFD1_k127_2414544_0 Phospholipase D Transphosphatidylase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 387.0
HFD1_k127_2414544_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000003818 218.0
HFD1_k127_2414544_2 Low affinity iron permease - - - 0.000000000000000000000000000000000001451 152.0
HFD1_k127_2414544_3 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000151 133.0
HFD1_k127_2443333_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 487.0
HFD1_k127_2443333_1 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000002334 126.0
HFD1_k127_2479736_0 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 345.0
HFD1_k127_2479736_1 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 306.0
HFD1_k127_2479736_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000001197 143.0
HFD1_k127_2479736_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000003956 78.0
HFD1_k127_2479736_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000005909 54.0
HFD1_k127_2482487_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.526e-232 748.0
HFD1_k127_2482487_1 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 450.0
HFD1_k127_2482487_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005726 269.0
HFD1_k127_2482487_3 methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000003116 202.0
HFD1_k127_2482487_4 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000001523 197.0
HFD1_k127_2482487_5 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000004114 178.0
HFD1_k127_2482487_6 Haem-degrading - - - 0.0000000000000000000002164 97.0
HFD1_k127_2482487_7 PAP2 superfamily - - - 0.000000000008247 76.0
HFD1_k127_2483603_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 443.0
HFD1_k127_2483603_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 268.0
HFD1_k127_2483603_10 AraC-like ligand binding domain - - - 0.0000000000000000000000173 102.0
HFD1_k127_2483603_12 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.000307 45.0
HFD1_k127_2483603_2 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000373 279.0
HFD1_k127_2483603_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000007295 226.0
HFD1_k127_2483603_4 Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000007461 203.0
HFD1_k127_2483603_5 Exopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000002346 213.0
HFD1_k127_2483603_6 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000004067 182.0
HFD1_k127_2483603_7 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000001087 154.0
HFD1_k127_2483603_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000002235 150.0
HFD1_k127_2483603_9 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000005965 120.0
HFD1_k127_2490127_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 358.0
HFD1_k127_2490127_1 Peptidase S53 propeptide K08677 - - 0.0000000000000000000000000000000000003437 155.0
HFD1_k127_2490127_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000008929 53.0
HFD1_k127_2495346_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928 533.0
HFD1_k127_2495346_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 446.0
HFD1_k127_2495346_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000002869 218.0
HFD1_k127_2495346_11 Response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000003048 205.0
HFD1_k127_2495346_12 Protein of unknown function DUF47 K02039,K07220 - - 0.0000000000000000000000000000000000000000000000002195 183.0
HFD1_k127_2495346_13 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000002896 181.0
HFD1_k127_2495346_14 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000001777 145.0
HFD1_k127_2495346_15 cheY-homologous receiver domain - - - 0.00000000000000000000000000000001793 131.0
HFD1_k127_2495346_16 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000003542 125.0
HFD1_k127_2495346_17 Pyruvate phosphate dikinase - - - 0.00002544 54.0
HFD1_k127_2495346_2 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 413.0
HFD1_k127_2495346_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 399.0
HFD1_k127_2495346_4 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 397.0
HFD1_k127_2495346_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 370.0
HFD1_k127_2495346_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 331.0
HFD1_k127_2495346_7 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 325.0
HFD1_k127_2495346_8 Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006431 290.0
HFD1_k127_2495346_9 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001031 261.0
HFD1_k127_2503095_0 COG0474 Cation transport ATPase K01531 - 3.6.3.2 0.0 1327.0
HFD1_k127_2503095_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1305.0
HFD1_k127_2503095_10 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 471.0
HFD1_k127_2503095_11 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 419.0
HFD1_k127_2503095_12 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 432.0
HFD1_k127_2503095_13 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 415.0
HFD1_k127_2503095_14 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 428.0
HFD1_k127_2503095_15 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 398.0
HFD1_k127_2503095_16 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 385.0
HFD1_k127_2503095_17 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 385.0
HFD1_k127_2503095_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 389.0
HFD1_k127_2503095_19 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 385.0
HFD1_k127_2503095_2 Belongs to the peptidase M16 family K07263 - - 0.0 1131.0
HFD1_k127_2503095_20 Acetamidase formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 345.0
HFD1_k127_2503095_21 TOBE domain K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 344.0
HFD1_k127_2503095_22 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 344.0
HFD1_k127_2503095_23 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 319.0
HFD1_k127_2503095_24 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 330.0
HFD1_k127_2503095_25 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002801 295.0
HFD1_k127_2503095_26 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000403 307.0
HFD1_k127_2503095_27 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004142 256.0
HFD1_k127_2503095_28 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000001553 235.0
HFD1_k127_2503095_29 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001136 240.0
HFD1_k127_2503095_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 2.12e-245 786.0
HFD1_k127_2503095_30 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004576 235.0
HFD1_k127_2503095_31 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000003956 205.0
HFD1_k127_2503095_32 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000894 192.0
HFD1_k127_2503095_34 ABC-type multidrug transport system ATPase K01990 - - 0.000000000000000000000000000000000000005172 158.0
HFD1_k127_2503095_35 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000001468 149.0
HFD1_k127_2503095_36 diguanylate cyclase - - - 0.00000000000000000000000000000362 135.0
HFD1_k127_2503095_37 Transcriptional regulator K02019 - - 0.0000000000000000000000003655 111.0
HFD1_k127_2503095_38 - - - - 0.00000000000000000000003734 105.0
HFD1_k127_2503095_39 helix_turn_helix, mercury resistance - - - 0.000000000000000000001289 100.0
HFD1_k127_2503095_4 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 6.672e-241 765.0
HFD1_k127_2503095_40 PhoQ Sensor - - - 0.000000000000000000002673 107.0
HFD1_k127_2503095_41 Response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000005658 105.0
HFD1_k127_2503095_42 - - - - 0.00000000000000002919 89.0
HFD1_k127_2503095_43 Adenylate cyclase - - - 0.00000000000000004095 89.0
HFD1_k127_2503095_44 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000001275 76.0
HFD1_k127_2503095_45 Autotransporter beta-domain - - - 0.000000000001262 83.0
HFD1_k127_2503095_47 Protein of unknown function (DUF2662) - - - 0.000000000008519 74.0
HFD1_k127_2503095_48 DNA-templated transcription, initiation K03088 - - 0.000003138 50.0
HFD1_k127_2503095_49 Predicted membrane protein (DUF2127) - - - 0.00001511 54.0
HFD1_k127_2503095_5 Involved in the tonB-independent uptake of proteins - - - 3.525e-225 727.0
HFD1_k127_2503095_6 Involved in the tonB-independent uptake of proteins - - - 2.248e-223 724.0
HFD1_k127_2503095_7 Protein tyrosine kinase K12132 - 2.7.11.1 1.93e-211 692.0
HFD1_k127_2503095_8 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 559.0
HFD1_k127_2503095_9 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 498.0
HFD1_k127_2505914_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 417.0
HFD1_k127_2505914_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 400.0
HFD1_k127_2505914_2 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 346.0
HFD1_k127_2505914_3 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 349.0
HFD1_k127_2505914_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000048 133.0
HFD1_k127_2505914_5 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000006417 56.0
HFD1_k127_2505914_6 Adenylate cyclase - - - 0.00003383 49.0
HFD1_k127_2511757_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.364e-225 708.0
HFD1_k127_2511757_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 515.0
HFD1_k127_2511757_10 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000001351 118.0
HFD1_k127_2511757_11 Biotin-requiring enzyme - - - 0.0000000000005965 79.0
HFD1_k127_2511757_12 Tetratricopeptide TPR_2 repeat protein - - - 0.00001926 56.0
HFD1_k127_2511757_13 Protein of unknown function (DUF507) K09804 - - 0.00002545 50.0
HFD1_k127_2511757_14 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00003126 50.0
HFD1_k127_2511757_15 modulator of DNA gyrase K03592 - - 0.00008091 55.0
HFD1_k127_2511757_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 491.0
HFD1_k127_2511757_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 343.0
HFD1_k127_2511757_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000003346 230.0
HFD1_k127_2511757_5 Peptidase family M20/M25/M40 - - - 0.0000000000000000000000000000000000000107 164.0
HFD1_k127_2511757_6 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000003794 142.0
HFD1_k127_2511757_7 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000001698 141.0
HFD1_k127_2511757_8 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000003243 122.0
HFD1_k127_2511757_9 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000001398 131.0
HFD1_k127_2514949_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001519 298.0
HFD1_k127_2514949_1 Outer membrane receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003168 278.0
HFD1_k127_2514949_2 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000002493 218.0
HFD1_k127_2514949_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000007428 163.0
HFD1_k127_2514949_5 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000001355 133.0
HFD1_k127_2514949_6 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000007431 103.0
HFD1_k127_2514949_7 oxidoreductase activity - - - 0.000000000000002739 89.0
HFD1_k127_2514949_8 chaperone-mediated protein folding - - - 0.0000000003417 73.0
HFD1_k127_2514949_9 Peptidase M56 - - - 0.00000237 60.0
HFD1_k127_2570540_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.081e-237 755.0
HFD1_k127_2570540_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 574.0
HFD1_k127_2570540_10 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001691 266.0
HFD1_k127_2570540_11 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000122 226.0
HFD1_k127_2570540_12 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000001779 196.0
HFD1_k127_2570540_13 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000003316 140.0
HFD1_k127_2570540_14 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.0000000000000000000000000000000284 135.0
HFD1_k127_2570540_15 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000002755 130.0
HFD1_k127_2570540_16 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000102 136.0
HFD1_k127_2570540_17 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000009851 121.0
HFD1_k127_2570540_18 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000003589 97.0
HFD1_k127_2570540_19 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000002303 86.0
HFD1_k127_2570540_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 444.0
HFD1_k127_2570540_20 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000373 82.0
HFD1_k127_2570540_21 Protein of unknown function (FYDLN_acid) - - - 0.0000000000008904 72.0
HFD1_k127_2570540_23 Tetratricopeptide repeat - - - 0.00000003759 64.0
HFD1_k127_2570540_24 Tetratricopeptide repeat - - - 0.0000005668 61.0
HFD1_k127_2570540_25 Two component regulator propeller - - - 0.00000161 61.0
HFD1_k127_2570540_26 chaperone-mediated protein folding - - - 0.0002024 54.0
HFD1_k127_2570540_27 Domain of unknown function DUF11 - - - 0.0003081 54.0
HFD1_k127_2570540_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 369.0
HFD1_k127_2570540_4 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 339.0
HFD1_k127_2570540_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 327.0
HFD1_k127_2570540_6 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 342.0
HFD1_k127_2570540_7 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 309.0
HFD1_k127_2570540_8 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 295.0
HFD1_k127_2570540_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002155 293.0
HFD1_k127_2582575_0 Oligoendopeptidase f - - - 4.549e-255 804.0
HFD1_k127_2582575_1 protein kinase activity - - - 8.916e-197 645.0
HFD1_k127_2582575_10 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 341.0
HFD1_k127_2582575_11 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 354.0
HFD1_k127_2582575_12 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 313.0
HFD1_k127_2582575_13 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 298.0
HFD1_k127_2582575_14 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 306.0
HFD1_k127_2582575_15 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.000000000000000000000000000000000000000000000000000006583 217.0
HFD1_k127_2582575_16 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000001626 154.0
HFD1_k127_2582575_17 pfam nudix - - - 0.00000000000000000000000000000000004596 142.0
HFD1_k127_2582575_18 - - - - 0.000000000000000000000000000000000752 140.0
HFD1_k127_2582575_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 595.0
HFD1_k127_2582575_20 Transcriptional regulator K07729 - - 0.00000000000000000000002641 103.0
HFD1_k127_2582575_21 Lysin motif - - - 0.000000000000000002419 95.0
HFD1_k127_2582575_22 PFAM S23 ribosomal protein - - - 0.000000000000000009418 94.0
HFD1_k127_2582575_23 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000002884 50.0
HFD1_k127_2582575_24 - - - - 0.000026 53.0
HFD1_k127_2582575_25 - - - - 0.00002828 54.0
HFD1_k127_2582575_26 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0001865 53.0
HFD1_k127_2582575_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 566.0
HFD1_k127_2582575_4 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 563.0
HFD1_k127_2582575_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 542.0
HFD1_k127_2582575_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 538.0
HFD1_k127_2582575_7 O-methyltransferase activity - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 532.0
HFD1_k127_2582575_8 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 413.0
HFD1_k127_2582575_9 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 371.0
HFD1_k127_2585759_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 371.0
HFD1_k127_2585759_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 316.0
HFD1_k127_2585759_10 Chlorophyllase - - - 0.00000000000000000000000000000000000000008885 173.0
HFD1_k127_2585759_11 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000006517 158.0
HFD1_k127_2585759_12 - - - - 0.00000000000000000000000000000000000005666 154.0
HFD1_k127_2585759_13 - - - - 0.0000000000000000000000007538 115.0
HFD1_k127_2585759_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 310.0
HFD1_k127_2585759_3 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 305.0
HFD1_k127_2585759_4 Pfam:Arch_ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004701 284.0
HFD1_k127_2585759_5 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005017 241.0
HFD1_k127_2585759_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000003856 250.0
HFD1_k127_2585759_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000001005 241.0
HFD1_k127_2585759_8 - - - - 0.0000000000000000000000000000000000000000000000000002063 194.0
HFD1_k127_2585759_9 Hydrolase - - - 0.000000000000000000000000000000000000000000000000006093 205.0
HFD1_k127_2635513_0 Involved in the tonB-independent uptake of proteins - - - 9.607e-225 724.0
HFD1_k127_2635513_1 Involved in the tonB-independent uptake of proteins - - - 1.978e-215 709.0
HFD1_k127_2635513_10 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 357.0
HFD1_k127_2635513_11 - - - - 0.0000000000000000000000000000000000000009304 166.0
HFD1_k127_2635513_12 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000003225 122.0
HFD1_k127_2635513_13 Regulatory protein, FmdB family - - - 0.00000000000000927 76.0
HFD1_k127_2635513_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 2.774e-214 698.0
HFD1_k127_2635513_3 Protein kinase domain K12132 - 2.7.11.1 4.467e-213 691.0
HFD1_k127_2635513_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.861e-203 679.0
HFD1_k127_2635513_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 601.0
HFD1_k127_2635513_6 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 500.0
HFD1_k127_2635513_7 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 424.0
HFD1_k127_2635513_8 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 399.0
HFD1_k127_2635513_9 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 377.0
HFD1_k127_2666454_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 390.0
HFD1_k127_2666454_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 367.0
HFD1_k127_2666454_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 329.0
HFD1_k127_2666454_3 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000002068 142.0
HFD1_k127_2666454_4 - - - - 0.00000000000000000001768 93.0
HFD1_k127_2666454_5 PFAM Oxidoreductase, molybdopterin binding - - - 0.000000000001374 74.0
HFD1_k127_2671750_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1494.0
HFD1_k127_2671750_1 Sodium:solute symporter family - - - 8e-291 901.0
HFD1_k127_2671750_10 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 347.0
HFD1_k127_2671750_11 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 309.0
HFD1_k127_2671750_12 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000006027 260.0
HFD1_k127_2671750_13 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000272 245.0
HFD1_k127_2671750_14 PIN domain - - - 0.000000000000000000000000000000000000004576 154.0
HFD1_k127_2671750_15 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000003709 111.0
HFD1_k127_2671750_16 Nitrate reductase delta subunit - - - 0.00000000000000000000006959 111.0
HFD1_k127_2671750_17 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000002882 90.0
HFD1_k127_2671750_18 imidazolonepropionase activity - - - 0.00001158 48.0
HFD1_k127_2671750_2 Protein kinase domain K12132 - 2.7.11.1 4.848e-240 770.0
HFD1_k127_2671750_20 domain protein - - - 0.0009835 51.0
HFD1_k127_2671750_3 Involved in the tonB-independent uptake of proteins - - - 1.149e-232 747.0
HFD1_k127_2671750_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 556.0
HFD1_k127_2671750_5 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 534.0
HFD1_k127_2671750_6 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 505.0
HFD1_k127_2671750_7 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 479.0
HFD1_k127_2671750_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 384.0
HFD1_k127_2671750_9 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 388.0
HFD1_k127_2671790_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1732.0
HFD1_k127_2671790_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 5.26e-279 886.0
HFD1_k127_2671790_10 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 368.0
HFD1_k127_2671790_11 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 348.0
HFD1_k127_2671790_12 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 349.0
HFD1_k127_2671790_13 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 325.0
HFD1_k127_2671790_14 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000001039 284.0
HFD1_k127_2671790_15 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000009782 267.0
HFD1_k127_2671790_16 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000000000002148 242.0
HFD1_k127_2671790_17 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000002185 211.0
HFD1_k127_2671790_18 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000002122 217.0
HFD1_k127_2671790_19 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001231 221.0
HFD1_k127_2671790_2 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.584e-246 779.0
HFD1_k127_2671790_20 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000145 165.0
HFD1_k127_2671790_21 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000003953 143.0
HFD1_k127_2671790_22 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000001845 149.0
HFD1_k127_2671790_23 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000003201 121.0
HFD1_k127_2671790_24 Polymer-forming cytoskeletal - - - 0.000000000000000000004512 99.0
HFD1_k127_2671790_25 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000003513 98.0
HFD1_k127_2671790_26 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 0.00000000000000002634 94.0
HFD1_k127_2671790_27 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000005082 76.0
HFD1_k127_2671790_28 outer membrane autotransporter barrel domain protein - - - 0.0000000000003761 78.0
HFD1_k127_2671790_3 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.994e-205 659.0
HFD1_k127_2671790_30 Glutaredoxin-like domain (DUF836) - - - 0.00000000002262 74.0
HFD1_k127_2671790_31 - - - - 0.0002932 45.0
HFD1_k127_2671790_4 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 619.0
HFD1_k127_2671790_5 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 488.0
HFD1_k127_2671790_6 PFAM Amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 449.0
HFD1_k127_2671790_7 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 441.0
HFD1_k127_2671790_8 Aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 395.0
HFD1_k127_2671790_9 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 358.0
HFD1_k127_2816586_0 radical SAM domain protein - - - 3.559e-223 703.0
HFD1_k127_2816586_1 Phospholipase D Transphosphatidylase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 612.0
HFD1_k127_2816586_10 - - - - 0.0000000000000007402 81.0
HFD1_k127_2816586_12 Protein of unknown function (DUF2892) - - - 0.0000009684 56.0
HFD1_k127_2816586_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 339.0
HFD1_k127_2816586_3 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000005598 231.0
HFD1_k127_2816586_4 Low affinity iron permease - - - 0.00000000000000000000000000000000000000000000003354 178.0
HFD1_k127_2816586_5 - - - - 0.00000000000000000000000000000000000001519 154.0
HFD1_k127_2816586_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000001346 131.0
HFD1_k127_2816586_7 - - - - 0.0000000000000000000000000000001735 134.0
HFD1_k127_2816586_8 Transglycosylase associated protein - - - 0.00000000000000000000000001165 110.0
HFD1_k127_2816586_9 periplasmic or secreted lipoprotein - - - 0.00000000000000000002852 96.0
HFD1_k127_2821075_0 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 511.0
HFD1_k127_2824420_0 MacB-like periplasmic core domain - - - 2.004e-284 897.0
HFD1_k127_2824420_1 acetyl-CoA hydrolase K18118 - 2.8.3.18 2.438e-202 639.0
HFD1_k127_2824420_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 359.0
HFD1_k127_2824420_3 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000005778 169.0
HFD1_k127_2824420_4 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000006643 118.0
HFD1_k127_2824420_5 - - - - 0.000000000000000000000000005383 120.0
HFD1_k127_2824420_6 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000543 113.0
HFD1_k127_28904_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 4.902e-317 982.0
HFD1_k127_28904_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 431.0
HFD1_k127_28904_2 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001482 243.0
HFD1_k127_28904_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000001483 143.0
HFD1_k127_2910369_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 631.0
HFD1_k127_2910369_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000009459 147.0
HFD1_k127_2926914_0 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000595 150.0
HFD1_k127_2926914_1 cell redox homeostasis - - - 0.00000000000000000000000001536 116.0
HFD1_k127_2926914_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000002448 80.0
HFD1_k127_2926914_3 DoxX K03885,K16937 - 1.6.99.3,1.8.5.2 0.00000004521 61.0
HFD1_k127_2979558_0 Sortilin, neurotensin receptor 3, - - - 0.0 1166.0
HFD1_k127_2979558_1 tRNA synthetases class I (K) K01870 - 6.1.1.5 4.285e-280 891.0
HFD1_k127_2979558_10 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000004562 276.0
HFD1_k127_2979558_11 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000006832 253.0
HFD1_k127_2979558_12 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000119 250.0
HFD1_k127_2979558_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000002115 229.0
HFD1_k127_2979558_14 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000001413 234.0
HFD1_k127_2979558_15 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000001652 232.0
HFD1_k127_2979558_16 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000003352 227.0
HFD1_k127_2979558_17 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000218 226.0
HFD1_k127_2979558_18 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000003416 231.0
HFD1_k127_2979558_19 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000001141 221.0
HFD1_k127_2979558_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 514.0
HFD1_k127_2979558_20 lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000006372 213.0
HFD1_k127_2979558_21 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000002561 209.0
HFD1_k127_2979558_22 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000002287 200.0
HFD1_k127_2979558_23 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000002294 174.0
HFD1_k127_2979558_24 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000005147 172.0
HFD1_k127_2979558_25 3-dehydroquinate dehydratase activity K00014,K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000002088 171.0
HFD1_k127_2979558_26 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000003092 159.0
HFD1_k127_2979558_27 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.000000000000000000000000000000000000005043 166.0
HFD1_k127_2979558_28 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000003331 145.0
HFD1_k127_2979558_29 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.00000000000000000000000000000000503 141.0
HFD1_k127_2979558_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 484.0
HFD1_k127_2979558_30 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000009378 137.0
HFD1_k127_2979558_31 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000126 128.0
HFD1_k127_2979558_32 domain, Protein - - - 0.00000000000000000000000000006582 135.0
HFD1_k127_2979558_33 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000002439 130.0
HFD1_k127_2979558_34 - - - - 0.0000000000000000000000007426 117.0
HFD1_k127_2979558_35 Domain of unknown function (DUF4115) - - - 0.000000000000000000004267 103.0
HFD1_k127_2979558_36 - - - - 0.00000000000000000007699 102.0
HFD1_k127_2979558_37 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000008627 98.0
HFD1_k127_2979558_38 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000003318 69.0
HFD1_k127_2979558_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 421.0
HFD1_k127_2979558_5 ATP-dependent helicase activity K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 387.0
HFD1_k127_2979558_6 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 300.0
HFD1_k127_2979558_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002314 290.0
HFD1_k127_2979558_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000004958 273.0
HFD1_k127_2979558_9 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000002151 271.0
HFD1_k127_307188_0 Peptidase M14, carboxypeptidase A - - - 0.0 1312.0
HFD1_k127_307188_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.438e-198 637.0
HFD1_k127_307188_10 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007784 262.0
HFD1_k127_307188_11 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000007632 156.0
HFD1_k127_307188_12 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000006323 149.0
HFD1_k127_307188_13 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000002049 107.0
HFD1_k127_307188_14 ATP synthesis coupled electron transport K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000002064 101.0
HFD1_k127_307188_15 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000005743 98.0
HFD1_k127_307188_16 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000002928 90.0
HFD1_k127_307188_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000007735 72.0
HFD1_k127_307188_18 - - - - 0.000000000003055 72.0
HFD1_k127_307188_19 - - - - 0.00000000002854 73.0
HFD1_k127_307188_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 636.0
HFD1_k127_307188_20 Yip1 domain - - - 0.000000006237 67.0
HFD1_k127_307188_3 PFAM peptidase M61 - - - 7.192e-194 625.0
HFD1_k127_307188_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 530.0
HFD1_k127_307188_5 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 456.0
HFD1_k127_307188_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 349.0
HFD1_k127_307188_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 321.0
HFD1_k127_307188_8 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 325.0
HFD1_k127_307188_9 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 332.0
HFD1_k127_3105901_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.952e-293 919.0
HFD1_k127_3105901_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 551.0
HFD1_k127_3105901_10 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001293 296.0
HFD1_k127_3105901_11 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006809 288.0
HFD1_k127_3105901_12 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004354 265.0
HFD1_k127_3105901_13 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000001784 233.0
HFD1_k127_3105901_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000004166 221.0
HFD1_k127_3105901_15 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000002841 200.0
HFD1_k127_3105901_16 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000005912 207.0
HFD1_k127_3105901_17 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000001702 191.0
HFD1_k127_3105901_18 Ku70/Ku80 beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000005756 193.0
HFD1_k127_3105901_19 Cupin domain - - - 0.00000000000000000000000000000000000000000000001093 176.0
HFD1_k127_3105901_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 550.0
HFD1_k127_3105901_20 NmrA-like family - - - 0.00000000000000000000000000000000000000003306 158.0
HFD1_k127_3105901_21 TPM domain - - - 0.000000000000000000000000000000000000008429 162.0
HFD1_k127_3105901_22 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000002418 139.0
HFD1_k127_3105901_23 membrane - - - 0.0000000000000000000000008546 109.0
HFD1_k127_3105901_25 Peptidase family M1 domain - - - 0.00000000000000000001709 107.0
HFD1_k127_3105901_26 - - - - 0.00000000000000007163 88.0
HFD1_k127_3105901_27 Phosphoglycerate mutase family - - - 0.0000000000000008049 83.0
HFD1_k127_3105901_28 - - - - 0.000000000005528 68.0
HFD1_k127_3105901_29 PAN domain - - - 0.00000008083 63.0
HFD1_k127_3105901_3 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 451.0
HFD1_k127_3105901_31 PFAM Uncharacterised BCR, COG1649 - - - 0.00006212 48.0
HFD1_k127_3105901_32 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00006246 54.0
HFD1_k127_3105901_33 Protein of unknown function (DUF1328) - - - 0.0002625 53.0
HFD1_k127_3105901_4 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 391.0
HFD1_k127_3105901_5 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 394.0
HFD1_k127_3105901_6 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 348.0
HFD1_k127_3105901_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 321.0
HFD1_k127_3105901_8 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 299.0
HFD1_k127_3105901_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 299.0
HFD1_k127_3151357_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 406.0
HFD1_k127_3151357_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000003671 218.0
HFD1_k127_3151357_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000001087 138.0
HFD1_k127_32442_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 578.0
HFD1_k127_32442_1 Phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 340.0
HFD1_k127_32442_2 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003824 205.0
HFD1_k127_32442_3 Uncharacterized conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000002261 164.0
HFD1_k127_32442_4 DinB superfamily - - - 0.000000000000000000000000000000000000007235 152.0
HFD1_k127_32442_5 - - - - 0.000000000000000000000008838 105.0
HFD1_k127_3257068_0 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 7.029e-282 897.0
HFD1_k127_3257068_1 imidazolonepropionase activity K01443 - 3.5.1.25 1.206e-218 712.0
HFD1_k127_3257068_10 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005962 276.0
HFD1_k127_3257068_11 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006635 257.0
HFD1_k127_3257068_12 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000001133 231.0
HFD1_k127_3257068_13 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000006024 200.0
HFD1_k127_3257068_14 EVE domain - - - 0.000000000000000000000000000000000000000559 152.0
HFD1_k127_3257068_15 peptide-methionine (S)-S-oxide reductase activity K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000006312 149.0
HFD1_k127_3257068_16 - - - - 0.00000000000000000000000000000000000001984 151.0
HFD1_k127_3257068_17 TIGRFAM toxin-antitoxin system, toxin component, Txe YoeB family K19158 - - 0.000000000000000000000000000000000001352 139.0
HFD1_k127_3257068_18 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00000000000000000000000000000000008774 138.0
HFD1_k127_3257068_19 YCII-related domain - - - 0.0000000000000000000000000744 115.0
HFD1_k127_3257068_2 Prolyl oligopeptidase family - - - 5.156e-198 638.0
HFD1_k127_3257068_20 Protein of unknown function (DUF2911) - - - 0.0000000000000000002683 98.0
HFD1_k127_3257068_21 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.0000000000000000008978 89.0
HFD1_k127_3257068_22 cellulase activity - - - 0.000000000000000006125 99.0
HFD1_k127_3257068_24 TonB-dependent Receptor Plug K02014 - - 0.0000002692 53.0
HFD1_k127_3257068_25 - - - - 0.000001162 60.0
HFD1_k127_3257068_3 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 496.0
HFD1_k127_3257068_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 488.0
HFD1_k127_3257068_5 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 439.0
HFD1_k127_3257068_6 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 388.0
HFD1_k127_3257068_7 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 358.0
HFD1_k127_3257068_8 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 338.0
HFD1_k127_3257068_9 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 309.0
HFD1_k127_3274072_0 Involved in the tonB-independent uptake of proteins - - - 1.522e-196 643.0
HFD1_k127_3274072_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 529.0
HFD1_k127_3274072_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000399 170.0
HFD1_k127_3274072_3 - - - - 0.000000000000000000001474 106.0
HFD1_k127_3347591_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 8.451e-239 757.0
HFD1_k127_3347591_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 368.0
HFD1_k127_3347591_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 362.0
HFD1_k127_3347591_3 belongs to the carbohydrate kinase PfkB family K16370 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 334.0
HFD1_k127_3347591_4 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001576 282.0
HFD1_k127_3347591_5 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001968 283.0
HFD1_k127_3347591_6 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000002222 245.0
HFD1_k127_3347591_7 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000003466 205.0
HFD1_k127_3347591_8 bacterial OsmY and nodulation domain - - - 0.000000000000000000006122 100.0
HFD1_k127_3347591_9 Cbs domain K04767 - - 0.000000000000000003667 90.0
HFD1_k127_3391756_0 Belongs to the ClpA ClpB family K03696 - - 2.172e-284 895.0
HFD1_k127_3391756_1 PFAM tRNA synthetase class II (D K and N), nucleic acid binding OB-fold tRNA helicase-type K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 569.0
HFD1_k127_3391756_10 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 316.0
HFD1_k127_3391756_11 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 325.0
HFD1_k127_3391756_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 325.0
HFD1_k127_3391756_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 314.0
HFD1_k127_3391756_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 302.0
HFD1_k127_3391756_15 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004003 289.0
HFD1_k127_3391756_16 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000193 275.0
HFD1_k127_3391756_17 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000003817 270.0
HFD1_k127_3391756_18 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000007177 245.0
HFD1_k127_3391756_19 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000001151 240.0
HFD1_k127_3391756_2 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 522.0
HFD1_k127_3391756_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001223 231.0
HFD1_k127_3391756_21 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000001456 227.0
HFD1_k127_3391756_22 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000001642 227.0
HFD1_k127_3391756_23 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000553 219.0
HFD1_k127_3391756_24 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000001226 198.0
HFD1_k127_3391756_25 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000005629 189.0
HFD1_k127_3391756_26 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000001704 179.0
HFD1_k127_3391756_27 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000004795 180.0
HFD1_k127_3391756_28 Histidine kinase - - - 0.000000000000000000000000000000000000000005579 169.0
HFD1_k127_3391756_29 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000002075 153.0
HFD1_k127_3391756_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 532.0
HFD1_k127_3391756_30 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000009296 157.0
HFD1_k127_3391756_31 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000001598 163.0
HFD1_k127_3391756_32 Thioredoxin K03671 - - 0.00000000000000000000000000000000000001977 147.0
HFD1_k127_3391756_33 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000008855 136.0
HFD1_k127_3391756_34 Cation efflux family - - - 0.00000000000000000002939 100.0
HFD1_k127_3391756_35 Putative Fe-S cluster K00380 - 1.8.1.2 0.0000000000000000005039 95.0
HFD1_k127_3391756_36 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000001239 64.0
HFD1_k127_3391756_37 outer membrane chaperone Skp (OmpH) K06142 - - 0.00000224 58.0
HFD1_k127_3391756_38 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00001219 52.0
HFD1_k127_3391756_39 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.00001422 59.0
HFD1_k127_3391756_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 429.0
HFD1_k127_3391756_40 Belongs to the peptidase S16 family K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006508,GO:0006605,GO:0006625,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0016043,GO:0016485,GO:0019538,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043574,GO:0044238,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564 3.4.21.53 0.00008724 55.0
HFD1_k127_3391756_41 Domain of unknown function (DUF4149) - - - 0.0001698 50.0
HFD1_k127_3391756_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 397.0
HFD1_k127_3391756_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 351.0
HFD1_k127_3391756_7 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 348.0
HFD1_k127_3391756_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 313.0
HFD1_k127_3391756_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 314.0
HFD1_k127_3438730_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000894 273.0
HFD1_k127_3438730_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003757 255.0
HFD1_k127_3438730_2 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000003843 188.0
HFD1_k127_3438730_3 - - - - 0.0000001895 63.0
HFD1_k127_3438730_4 Sigma-70, region 4 K03088 - - 0.000004013 57.0
HFD1_k127_3438730_5 Lipocalin-like domain - - - 0.000007246 56.0
HFD1_k127_3446858_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 1.264e-254 803.0
HFD1_k127_3446858_1 4Fe-4S single cluster domain K06937 - - 1.65e-242 770.0
HFD1_k127_3446858_10 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 459.0
HFD1_k127_3446858_11 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 457.0
HFD1_k127_3446858_12 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 430.0
HFD1_k127_3446858_13 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 327.0
HFD1_k127_3446858_14 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 309.0
HFD1_k127_3446858_15 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 310.0
HFD1_k127_3446858_16 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 316.0
HFD1_k127_3446858_17 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002023 286.0
HFD1_k127_3446858_18 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001644 284.0
HFD1_k127_3446858_19 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004454 276.0
HFD1_k127_3446858_2 GTP-binding protein TypA K06207 - - 1.173e-206 662.0
HFD1_k127_3446858_20 PFAM ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003203 269.0
HFD1_k127_3446858_21 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008536 275.0
HFD1_k127_3446858_22 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000004204 251.0
HFD1_k127_3446858_23 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000008877 254.0
HFD1_k127_3446858_24 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000002403 234.0
HFD1_k127_3446858_25 PFAM Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000004383 237.0
HFD1_k127_3446858_26 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000005748 220.0
HFD1_k127_3446858_27 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000004882 190.0
HFD1_k127_3446858_28 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000005382 193.0
HFD1_k127_3446858_29 PFAM ABC-2 type transporter K01992,K09690 - - 0.0000000000000000000000000000000000000000006186 170.0
HFD1_k127_3446858_3 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 619.0
HFD1_k127_3446858_30 - - - - 0.000000000000000000000000000000000000002165 166.0
HFD1_k127_3446858_31 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000695 152.0
HFD1_k127_3446858_32 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000009433 157.0
HFD1_k127_3446858_33 methyltransferase activity - - - 0.0000000000000000000000000000000008421 142.0
HFD1_k127_3446858_34 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000003024 141.0
HFD1_k127_3446858_35 serine-type peptidase activity K01278 - 3.4.14.5 0.0000000000000000000000000000001049 130.0
HFD1_k127_3446858_36 ubiquitin K02927,K20276 - - 0.0000000000000000000000000000001233 144.0
HFD1_k127_3446858_37 Methyltransferase domain - - - 0.0000000000000000000000000001545 132.0
HFD1_k127_3446858_38 membrane - - - 0.0000000000000000000000000005773 120.0
HFD1_k127_3446858_39 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000001122 116.0
HFD1_k127_3446858_4 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 586.0
HFD1_k127_3446858_40 endo-1,4-beta-xylanase activity - - - 0.00000000000000000000006033 111.0
HFD1_k127_3446858_41 Smr domain - - - 0.0000000000000000000001256 99.0
HFD1_k127_3446858_42 diguanylate cyclase - - - 0.0000000000000000000007395 109.0
HFD1_k127_3446858_43 acetyltransferase - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.0000000000000000000009853 101.0
HFD1_k127_3446858_44 PFAM translation initiation factor SUI1 K03113 - - 0.00000000000000000002402 97.0
HFD1_k127_3446858_45 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000002735 94.0
HFD1_k127_3446858_46 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000001623 97.0
HFD1_k127_3446858_47 Transcriptional regulatory protein, C terminal - - - 0.00000000000000003643 89.0
HFD1_k127_3446858_48 PFAM Anti-sigma-K factor RskA - - - 0.0000000000000001776 89.0
HFD1_k127_3446858_49 Peptidase, S9A B C family, catalytic domain protein K01278 - 3.4.14.5 0.0000000000000001803 81.0
HFD1_k127_3446858_5 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 544.0
HFD1_k127_3446858_50 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000009673 83.0
HFD1_k127_3446858_51 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000001163 77.0
HFD1_k127_3446858_52 DsrE/DsrF-like family - - - 0.000000000002034 71.0
HFD1_k127_3446858_53 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000004079 75.0
HFD1_k127_3446858_54 LysM domain - - - 0.000000000009322 76.0
HFD1_k127_3446858_55 polysaccharide deacetylase - - - 0.00000000002236 78.0
HFD1_k127_3446858_56 mttA/Hcf106 family K03116 - - 0.00000000002985 66.0
HFD1_k127_3446858_57 redox protein, regulator of disulfide bond formation - - - 0.0000000006067 67.0
HFD1_k127_3446858_58 Domain of unknown function (DUF4331) - - - 0.0000000008426 60.0
HFD1_k127_3446858_59 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000001308 59.0
HFD1_k127_3446858_6 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 522.0
HFD1_k127_3446858_60 - - - - 0.0000001945 58.0
HFD1_k127_3446858_61 WD40-like Beta Propeller - - - 0.000003416 57.0
HFD1_k127_3446858_62 PFAM helix-turn-helix, Fis-type - - - 0.00003223 51.0
HFD1_k127_3446858_63 Belongs to the peptidase S8 family - - - 0.0001897 54.0
HFD1_k127_3446858_7 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 483.0
HFD1_k127_3446858_8 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 495.0
HFD1_k127_3446858_9 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 471.0
HFD1_k127_3524200_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 4.487e-308 967.0
HFD1_k127_3524200_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 601.0
HFD1_k127_3524200_10 Single Cache domain 2 K03406 - - 0.000000000000000000000000000000000000000000000000000000003096 204.0
HFD1_k127_3524200_11 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000003498 175.0
HFD1_k127_3524200_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000004726 136.0
HFD1_k127_3524200_13 protein histidine kinase activity K06375 - - 0.00000000000000000000000000006744 124.0
HFD1_k127_3524200_14 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.000000000000000000000000476 111.0
HFD1_k127_3524200_15 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000005069 117.0
HFD1_k127_3524200_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000001155 100.0
HFD1_k127_3524200_17 Protein tyrosine kinase - - - 0.000000000000000000002481 97.0
HFD1_k127_3524200_18 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000001878 93.0
HFD1_k127_3524200_19 Cytochrome c K17223 - - 0.0000000000002986 79.0
HFD1_k127_3524200_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 585.0
HFD1_k127_3524200_20 protein secretion K03116 GO:0008150,GO:0040007 - 0.000000000003871 69.0
HFD1_k127_3524200_21 Transcriptional regulatory protein, C terminal - - - 0.000000000007159 74.0
HFD1_k127_3524200_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 500.0
HFD1_k127_3524200_4 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 353.0
HFD1_k127_3524200_5 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 297.0
HFD1_k127_3524200_6 Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007644 282.0
HFD1_k127_3524200_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001331 244.0
HFD1_k127_3524200_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000006224 249.0
HFD1_k127_3524200_9 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000003156 229.0
HFD1_k127_3533785_0 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 526.0
HFD1_k127_3533785_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 449.0
HFD1_k127_3533785_10 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005735 263.0
HFD1_k127_3533785_11 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000001123 236.0
HFD1_k127_3533785_12 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000701 190.0
HFD1_k127_3533785_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000005104 175.0
HFD1_k127_3533785_14 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000003095 164.0
HFD1_k127_3533785_15 PFAM FecR protein - - - 0.0000000000000000000008982 109.0
HFD1_k127_3533785_16 fatty acid desaturase - - - 0.00000000000001042 85.0
HFD1_k127_3533785_17 Involved in formation and maintenance of cell shape K03570 - - 0.000000000002358 78.0
HFD1_k127_3533785_18 - - - - 0.000103 53.0
HFD1_k127_3533785_2 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 454.0
HFD1_k127_3533785_3 COG0006 Xaa-Pro aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 395.0
HFD1_k127_3533785_4 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 391.0
HFD1_k127_3533785_5 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 314.0
HFD1_k127_3533785_6 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 295.0
HFD1_k127_3533785_7 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003947 295.0
HFD1_k127_3533785_8 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001818 287.0
HFD1_k127_3533785_9 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001176 279.0
HFD1_k127_3602522_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.926e-277 871.0
HFD1_k127_3602522_1 Fumarase C-terminus K01676 - 4.2.1.2 5.182e-250 777.0
HFD1_k127_3602522_10 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 386.0
HFD1_k127_3602522_11 Arginosuccinate synthase K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 382.0
HFD1_k127_3602522_12 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 370.0
HFD1_k127_3602522_13 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 370.0
HFD1_k127_3602522_14 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 363.0
HFD1_k127_3602522_15 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 337.0
HFD1_k127_3602522_16 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 335.0
HFD1_k127_3602522_17 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 308.0
HFD1_k127_3602522_18 NHL repeat K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 312.0
HFD1_k127_3602522_19 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001371 283.0
HFD1_k127_3602522_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 7.021e-206 663.0
HFD1_k127_3602522_20 Mo-molybdopterin cofactor biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002888 286.0
HFD1_k127_3602522_21 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001196 272.0
HFD1_k127_3602522_22 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000001325 248.0
HFD1_k127_3602522_23 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000587 246.0
HFD1_k127_3602522_24 Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde K05829 - - 0.0000000000000000000000000000000000000000000000000000000000000000001038 256.0
HFD1_k127_3602522_25 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000002444 241.0
HFD1_k127_3602522_26 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000002903 243.0
HFD1_k127_3602522_27 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000263 237.0
HFD1_k127_3602522_28 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000229 232.0
HFD1_k127_3602522_29 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000004767 202.0
HFD1_k127_3602522_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K02805 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 547.0
HFD1_k127_3602522_30 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000006832 189.0
HFD1_k127_3602522_31 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000002861 188.0
HFD1_k127_3602522_32 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000002565 196.0
HFD1_k127_3602522_33 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000006134 171.0
HFD1_k127_3602522_34 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000002248 167.0
HFD1_k127_3602522_35 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000007072 175.0
HFD1_k127_3602522_36 - - - - 0.000000000000000000000000000000000000004619 167.0
HFD1_k127_3602522_37 NHL repeat - - - 0.00000000000000000000000000000000000001281 168.0
HFD1_k127_3602522_38 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000007299 137.0
HFD1_k127_3602522_39 acetyltransferase - - - 0.00000000000000000000000000000001274 142.0
HFD1_k127_3602522_4 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 556.0
HFD1_k127_3602522_40 NHL repeat - - - 0.000000000000000000000000000000111 145.0
HFD1_k127_3602522_41 Methyltransferase domain - - - 0.0000000000000000000000195 113.0
HFD1_k127_3602522_42 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000002019 114.0
HFD1_k127_3602522_43 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000002596 106.0
HFD1_k127_3602522_44 GYD domain - - - 0.0000000000000000002071 94.0
HFD1_k127_3602522_45 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503,K19710,K21220 - 2.5.1.3,2.7.7.53 0.00000000000000001718 91.0
HFD1_k127_3602522_48 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000004185 61.0
HFD1_k127_3602522_49 Involved in the tonB-independent uptake of proteins - - - 0.00004872 46.0
HFD1_k127_3602522_5 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 529.0
HFD1_k127_3602522_6 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 509.0
HFD1_k127_3602522_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 469.0
HFD1_k127_3602522_8 Adenosine/AMP deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 433.0
HFD1_k127_3602522_9 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 414.0
HFD1_k127_3613072_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 629.0
HFD1_k127_3613072_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005124 295.0
HFD1_k127_3613072_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000003989 215.0
HFD1_k127_3613072_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000002301 126.0
HFD1_k127_3646056_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 511.0
HFD1_k127_3646056_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 334.0
HFD1_k127_3646056_2 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000003687 154.0
HFD1_k127_3646056_3 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000007515 130.0
HFD1_k127_3646056_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00004885 56.0
HFD1_k127_3650122_0 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 509.0
HFD1_k127_3650122_1 - - - - 0.000000000000000000000000000000000000000000000000000000000003707 220.0
HFD1_k127_3650122_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000111 215.0
HFD1_k127_3650122_3 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000147 174.0
HFD1_k127_3650122_4 - - - - 0.00000000000000002468 90.0
HFD1_k127_3650122_5 oxidoreductase activity - - - 0.00001555 56.0
HFD1_k127_3650122_6 PFAM PEGA domain - - - 0.00004045 52.0
HFD1_k127_3651259_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1392.0
HFD1_k127_3651259_1 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1302.0
HFD1_k127_3651259_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1144.0
HFD1_k127_3651259_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 3.56e-322 1004.0
HFD1_k127_3651259_4 Polysulphide reductase, NrfD K00124 - - 9.32e-304 959.0
HFD1_k127_3651259_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 2.323e-245 767.0
HFD1_k127_3651259_6 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 4.468e-208 655.0
HFD1_k127_3651259_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 462.0
HFD1_k127_3651259_8 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 428.0
HFD1_k127_3651259_9 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000000000000000000000000000000000000000005284 239.0
HFD1_k127_3759908_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1284.0
HFD1_k127_3759908_1 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 2.337e-272 859.0
HFD1_k127_3759908_10 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 441.0
HFD1_k127_3759908_11 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 407.0
HFD1_k127_3759908_12 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 376.0
HFD1_k127_3759908_13 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 376.0
HFD1_k127_3759908_14 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 362.0
HFD1_k127_3759908_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 371.0
HFD1_k127_3759908_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 353.0
HFD1_k127_3759908_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 338.0
HFD1_k127_3759908_18 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 320.0
HFD1_k127_3759908_19 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 325.0
HFD1_k127_3759908_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 5.555e-206 662.0
HFD1_k127_3759908_20 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007536 266.0
HFD1_k127_3759908_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001308 247.0
HFD1_k127_3759908_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000126 217.0
HFD1_k127_3759908_23 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000005352 235.0
HFD1_k127_3759908_24 GHMP kinase K00869,K07031 - 2.7.1.168,2.7.1.36 0.000000000000000000000000000000000000000000000000000003539 203.0
HFD1_k127_3759908_25 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000006619 202.0
HFD1_k127_3759908_26 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000009874 180.0
HFD1_k127_3759908_27 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000002627 173.0
HFD1_k127_3759908_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.00000000000000000000000000000000000000002349 160.0
HFD1_k127_3759908_29 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000000000000000000000000000000009281 158.0
HFD1_k127_3759908_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 595.0
HFD1_k127_3759908_30 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000002153 164.0
HFD1_k127_3759908_31 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000002005 154.0
HFD1_k127_3759908_32 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000001503 126.0
HFD1_k127_3759908_33 - - - - 0.0000000000000000000000000001133 121.0
HFD1_k127_3759908_34 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000004129 128.0
HFD1_k127_3759908_35 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05580 - 1.6.5.3 0.0000000000000000000000000309 114.0
HFD1_k127_3759908_36 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000002057 112.0
HFD1_k127_3759908_37 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000003402 119.0
HFD1_k127_3759908_38 - - - - 0.0000000000005978 78.0
HFD1_k127_3759908_39 ECF sigma factor K03088 - - 0.000000000001269 78.0
HFD1_k127_3759908_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 578.0
HFD1_k127_3759908_40 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000001237 66.0
HFD1_k127_3759908_41 Polymer-forming cytoskeletal - - - 0.000000005093 68.0
HFD1_k127_3759908_42 O-Antigen ligase - - - 0.00000009419 65.0
HFD1_k127_3759908_43 ATP-independent chaperone mediated protein folding K06006 - - 0.00009995 51.0
HFD1_k127_3759908_44 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0003898 47.0
HFD1_k127_3759908_5 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 590.0
HFD1_k127_3759908_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 567.0
HFD1_k127_3759908_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 550.0
HFD1_k127_3759908_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 469.0
HFD1_k127_3759908_9 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 464.0
HFD1_k127_37607_0 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 364.0
HFD1_k127_37607_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 323.0
HFD1_k127_37607_2 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000006224 125.0
HFD1_k127_37607_3 phosphorelay signal transduction system K14987 - - 0.000000000000000000000001173 107.0
HFD1_k127_37607_4 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000002961 85.0
HFD1_k127_3834889_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1680.0
HFD1_k127_3834889_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 430.0
HFD1_k127_3834889_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 394.0
HFD1_k127_3834889_3 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 392.0
HFD1_k127_3834889_4 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000001269 214.0
HFD1_k127_3834889_5 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000001598 199.0
HFD1_k127_3834889_6 Pas domain - - - 0.0000000000000000000003259 104.0
HFD1_k127_3834889_7 helix_turn_helix, Lux Regulon K07684 - - 0.0000000007005 68.0
HFD1_k127_3834889_8 Universal stress protein - - - 0.0001401 51.0
HFD1_k127_3859434_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 3064.0
HFD1_k127_3859434_1 B12 binding domain K00548 - 2.1.1.13 0.0 1335.0
HFD1_k127_3859434_10 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 621.0
HFD1_k127_3859434_11 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 611.0
HFD1_k127_3859434_12 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 601.0
HFD1_k127_3859434_13 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 583.0
HFD1_k127_3859434_14 Dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 542.0
HFD1_k127_3859434_15 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 508.0
HFD1_k127_3859434_16 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 486.0
HFD1_k127_3859434_17 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 493.0
HFD1_k127_3859434_18 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 496.0
HFD1_k127_3859434_19 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 432.0
HFD1_k127_3859434_2 cellulose binding - - - 1.575e-230 754.0
HFD1_k127_3859434_20 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 400.0
HFD1_k127_3859434_21 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 373.0
HFD1_k127_3859434_22 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 375.0
HFD1_k127_3859434_23 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008093 392.0
HFD1_k127_3859434_24 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 374.0
HFD1_k127_3859434_25 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 379.0
HFD1_k127_3859434_26 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 361.0
HFD1_k127_3859434_27 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 355.0
HFD1_k127_3859434_28 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 325.0
HFD1_k127_3859434_29 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 321.0
HFD1_k127_3859434_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 2.874e-226 708.0
HFD1_k127_3859434_30 Iron ABC transporter substrate-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 318.0
HFD1_k127_3859434_31 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 320.0
HFD1_k127_3859434_32 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 295.0
HFD1_k127_3859434_33 Belongs to the ABC transporter superfamily K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 295.0
HFD1_k127_3859434_34 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 287.0
HFD1_k127_3859434_35 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001414 296.0
HFD1_k127_3859434_36 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003341 308.0
HFD1_k127_3859434_37 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006115 302.0
HFD1_k127_3859434_38 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001526 279.0
HFD1_k127_3859434_39 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002004 285.0
HFD1_k127_3859434_4 Domain of unknown function (DUF4070) - - - 6.275e-220 694.0
HFD1_k127_3859434_40 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002503 277.0
HFD1_k127_3859434_41 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002593 271.0
HFD1_k127_3859434_42 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004401 261.0
HFD1_k127_3859434_43 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000755 267.0
HFD1_k127_3859434_44 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000129 255.0
HFD1_k127_3859434_45 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003663 239.0
HFD1_k127_3859434_46 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006921 248.0
HFD1_k127_3859434_47 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001204 236.0
HFD1_k127_3859434_48 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000008512 237.0
HFD1_k127_3859434_49 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000001213 231.0
HFD1_k127_3859434_5 Flotillin K07192 - - 1.936e-219 689.0
HFD1_k127_3859434_50 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000009896 220.0
HFD1_k127_3859434_51 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000001089 229.0
HFD1_k127_3859434_52 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000001154 218.0
HFD1_k127_3859434_53 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000006559 198.0
HFD1_k127_3859434_54 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000002702 198.0
HFD1_k127_3859434_55 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000002744 210.0
HFD1_k127_3859434_56 sequence-specific DNA binding K03719 - - 0.000000000000000000000000000000000000000000000000002032 186.0
HFD1_k127_3859434_57 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.000000000000000000000000000000000000000000000000002745 207.0
HFD1_k127_3859434_58 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000000000000000000000000000000000000000004208 196.0
HFD1_k127_3859434_59 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000284 180.0
HFD1_k127_3859434_6 Peptidase m28 - - - 9.776e-210 674.0
HFD1_k127_3859434_60 Belongs to the metal hydrolase YfiT family - - - 0.00000000000000000000000000000000000000000000001014 181.0
HFD1_k127_3859434_61 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000001494 184.0
HFD1_k127_3859434_62 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000000000000000000000905 175.0
HFD1_k127_3859434_63 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor K10672,K10794 - 1.21.4.1,1.21.4.2 0.0000000000000000000000000000000000000000003624 164.0
HFD1_k127_3859434_64 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000004073 151.0
HFD1_k127_3859434_65 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000002898 152.0
HFD1_k127_3859434_67 DinB superfamily - - - 0.00000000000000000000000000000000002543 141.0
HFD1_k127_3859434_68 DinB family - - - 0.00000000000000000000000000000000006346 150.0
HFD1_k127_3859434_69 AhpC/TSA family - - - 0.0000000000000000000000000000000003137 145.0
HFD1_k127_3859434_7 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.145e-208 672.0
HFD1_k127_3859434_70 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000001266 135.0
HFD1_k127_3859434_71 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000054 133.0
HFD1_k127_3859434_72 CAAX protease self-immunity - - - 0.00000000000000000000000000000001102 144.0
HFD1_k127_3859434_73 smart pdz dhr glgf - - - 0.00000000000000000000000000000008135 141.0
HFD1_k127_3859434_74 Protein conserved in bacteria - - - 0.0000000000000000000000000000001619 142.0
HFD1_k127_3859434_75 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000001749 138.0
HFD1_k127_3859434_76 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.00000000000000000000000000002134 136.0
HFD1_k127_3859434_77 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000001507 115.0
HFD1_k127_3859434_78 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.00000000000000000000000002762 114.0
HFD1_k127_3859434_79 EamA-like transporter family - - - 0.000000000000000000000002847 116.0
HFD1_k127_3859434_8 PFAM peptidase M28 - - - 2.701e-202 646.0
HFD1_k127_3859434_80 peptidase - - - 0.000000000000000000000005609 112.0
HFD1_k127_3859434_81 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000001373 117.0
HFD1_k127_3859434_82 response regulator - - - 0.000000000000000000004975 103.0
HFD1_k127_3859434_83 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000239 100.0
HFD1_k127_3859434_85 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.000000000000000005776 99.0
HFD1_k127_3859434_86 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000006264 91.0
HFD1_k127_3859434_87 Outer membrane protein beta-barrel domain - - - 0.0000000000000319 87.0
HFD1_k127_3859434_88 - - - - 0.0000000000001351 73.0
HFD1_k127_3859434_89 Phosphorylase superfamily K01243 - 3.2.2.9 0.00000000001915 74.0
HFD1_k127_3859434_9 serine threonine protein kinase K12132 - 2.7.11.1 1.334e-199 651.0
HFD1_k127_3859434_90 ABC-type transport system involved in multi-copper enzyme maturation permease component K19341 - - 0.00000000004803 73.0
HFD1_k127_3859434_91 Kelch-like family member 35 K10461,K13959 GO:0000151,GO:0005575,GO:0005622,GO:0005623,GO:0031461,GO:0031463,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1990234 - 0.00000000006015 72.0
HFD1_k127_3859434_92 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000002894 71.0
HFD1_k127_3859434_93 - - - - 0.0000000004869 71.0
HFD1_k127_3859434_94 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000002825 59.0
HFD1_k127_3859434_95 - - - - 0.000001317 62.0
HFD1_k127_3859434_96 Family of unknown function (DUF5335) - - - 0.000005756 55.0
HFD1_k127_3859434_97 PFAM Outer membrane efflux protein - - - 0.0002051 53.0
HFD1_k127_40322_0 AMP-binding enzyme K01897 - 6.2.1.3 2.775e-287 904.0
HFD1_k127_40322_1 amino acid K01999 - - 4.531e-197 625.0
HFD1_k127_40322_10 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 407.0
HFD1_k127_40322_11 amino acid transport system, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 405.0
HFD1_k127_40322_12 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 381.0
HFD1_k127_40322_13 transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 336.0
HFD1_k127_40322_14 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 319.0
HFD1_k127_40322_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 333.0
HFD1_k127_40322_16 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 303.0
HFD1_k127_40322_17 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
HFD1_k127_40322_18 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000003742 231.0
HFD1_k127_40322_19 transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000004547 226.0
HFD1_k127_40322_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 599.0
HFD1_k127_40322_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000002828 216.0
HFD1_k127_40322_21 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000003994 216.0
HFD1_k127_40322_22 ABC transporter permease K01992 - - 0.000000000000000000000000000000000000000000000000008477 191.0
HFD1_k127_40322_23 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000001988 175.0
HFD1_k127_40322_24 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000006088 142.0
HFD1_k127_40322_25 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000001019 146.0
HFD1_k127_40322_26 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000002564 127.0
HFD1_k127_40322_27 50S ribosomal protein L31 K02909 - - 0.0000000000000000000000000008355 115.0
HFD1_k127_40322_28 Phosphoribosyl transferase domain - - - 0.00000000000000000000000001703 121.0
HFD1_k127_40322_29 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000006575 108.0
HFD1_k127_40322_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 506.0
HFD1_k127_40322_30 Cupin domain - - - 0.0000003198 57.0
HFD1_k127_40322_31 NB-ARC domain protein - - - 0.00002717 56.0
HFD1_k127_40322_32 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0008382 51.0
HFD1_k127_40322_4 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 525.0
HFD1_k127_40322_5 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 488.0
HFD1_k127_40322_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 477.0
HFD1_k127_40322_7 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 479.0
HFD1_k127_40322_8 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 427.0
HFD1_k127_40322_9 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 421.0
HFD1_k127_4103937_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1172.0
HFD1_k127_4103937_1 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 582.0
HFD1_k127_4103937_10 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000008428 176.0
HFD1_k127_4103937_11 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.0000000000000000000000000000001014 132.0
HFD1_k127_4103937_12 - - - - 0.00000000000000000000000004336 125.0
HFD1_k127_4103937_13 PFAM GCN5-related N-acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000009446 102.0
HFD1_k127_4103937_14 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000001711 85.0
HFD1_k127_4103937_15 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000001834 81.0
HFD1_k127_4103937_16 Deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.000000000002435 74.0
HFD1_k127_4103937_17 - - - - 0.000000007723 68.0
HFD1_k127_4103937_2 PAS fold-4 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 605.0
HFD1_k127_4103937_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 547.0
HFD1_k127_4103937_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 505.0
HFD1_k127_4103937_5 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 469.0
HFD1_k127_4103937_6 Glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 361.0
HFD1_k127_4103937_7 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 377.0
HFD1_k127_4103937_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000009139 247.0
HFD1_k127_4103937_9 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000371 205.0
HFD1_k127_4107640_0 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 308.0
HFD1_k127_4107640_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000007617 141.0
HFD1_k127_4107640_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000035 143.0
HFD1_k127_4107640_3 glycosyl transferase, family 39 - - - 0.000000000003477 74.0
HFD1_k127_4107640_4 Domain of unknown function (DUF4149) - - - 0.0001739 50.0
HFD1_k127_4156554_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000008049 203.0
HFD1_k127_4178087_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 367.0
HFD1_k127_4178087_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000004134 268.0
HFD1_k127_4191582_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 379.0
HFD1_k127_4191582_1 oxidoreductase activity - - - 0.000000000000000000001894 110.0
HFD1_k127_4191582_2 peptidyl-tyrosine sulfation - - - 0.000000000000006176 85.0
HFD1_k127_4191582_3 peptidyl-tyrosine sulfation - - - 0.00000000000557 79.0
HFD1_k127_4191582_4 COG0457 FOG TPR repeat - - - 0.00006949 54.0
HFD1_k127_4191582_5 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00009224 54.0
HFD1_k127_4211839_0 Involved in the tonB-independent uptake of proteins - - - 6.597e-226 727.0
HFD1_k127_4211839_1 Involved in the tonB-independent uptake of proteins - - - 3.878e-199 645.0
HFD1_k127_4211839_2 SAD/SRA domain - - - 0.00000000000000000000000000000000000000000000000000000003981 201.0
HFD1_k127_4211839_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000001016 185.0
HFD1_k127_4211839_4 HNH nucleases - - - 0.000000000000004616 76.0
HFD1_k127_4243889_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.157e-236 752.0
HFD1_k127_4243889_1 Involved in the tonB-independent uptake of proteins - - - 2.626e-221 715.0
HFD1_k127_4243889_10 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000002199 82.0
HFD1_k127_4243889_11 COG3209 Rhs family protein - - - 0.00000000000001883 87.0
HFD1_k127_4243889_12 Belongs to the peptidase S8 family - - - 0.00000000003573 76.0
HFD1_k127_4243889_13 - - - - 0.000000003315 59.0
HFD1_k127_4243889_14 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000004646 61.0
HFD1_k127_4243889_2 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 4.712e-201 635.0
HFD1_k127_4243889_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 2.545e-198 631.0
HFD1_k127_4243889_4 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 528.0
HFD1_k127_4243889_5 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 346.0
HFD1_k127_4243889_6 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 329.0
HFD1_k127_4243889_7 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000001419 202.0
HFD1_k127_4243889_8 - - - - 0.0000000000000000000000000000000008708 132.0
HFD1_k127_4243889_9 Domain of unknown function (DUF2383) - - - 0.000000000000000007567 91.0
HFD1_k127_4285838_0 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 375.0
HFD1_k127_4285838_1 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000004135 172.0
HFD1_k127_4285838_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000003697 134.0
HFD1_k127_4285838_3 - - - - 0.00000000000000000000003306 104.0
HFD1_k127_4285838_4 Tetratricopeptide repeat - - - 0.00000000000000003302 82.0
HFD1_k127_4291903_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 472.0
HFD1_k127_4291903_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000001123 160.0
HFD1_k127_435303_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.028e-266 856.0
HFD1_k127_435303_1 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 566.0
HFD1_k127_435303_10 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 411.0
HFD1_k127_435303_11 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 412.0
HFD1_k127_435303_12 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 383.0
HFD1_k127_435303_13 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 388.0
HFD1_k127_435303_14 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 340.0
HFD1_k127_435303_15 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 323.0
HFD1_k127_435303_16 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 293.0
HFD1_k127_435303_17 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003662 283.0
HFD1_k127_435303_18 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000385 286.0
HFD1_k127_435303_19 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000004462 281.0
HFD1_k127_435303_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 518.0
HFD1_k127_435303_20 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000008688 259.0
HFD1_k127_435303_21 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000002152 228.0
HFD1_k127_435303_22 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000001667 211.0
HFD1_k127_435303_23 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000003667 215.0
HFD1_k127_435303_24 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000003536 168.0
HFD1_k127_435303_25 Hydrogenase 4 membrane - - - 0.00000000000000000000000000000000000000002989 167.0
HFD1_k127_435303_26 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000008595 152.0
HFD1_k127_435303_27 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.000000000000000331 93.0
HFD1_k127_435303_28 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.0000000000000009097 85.0
HFD1_k127_435303_29 Essential cell division protein K03589 - - 0.00000000000002205 83.0
HFD1_k127_435303_3 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 508.0
HFD1_k127_435303_30 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000007386 68.0
HFD1_k127_435303_31 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0000004161 60.0
HFD1_k127_435303_32 Protein of unknown function (DUF454) K09790 - - 0.0005502 47.0
HFD1_k127_435303_4 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 504.0
HFD1_k127_435303_5 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 503.0
HFD1_k127_435303_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 445.0
HFD1_k127_435303_7 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 433.0
HFD1_k127_435303_8 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 432.0
HFD1_k127_435303_9 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 417.0
HFD1_k127_4354522_0 Sortilin, neurotensin receptor 3, - - - 0.0 1270.0
HFD1_k127_4354522_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 4.091e-217 682.0
HFD1_k127_4354522_10 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 402.0
HFD1_k127_4354522_11 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 323.0
HFD1_k127_4354522_12 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 319.0
HFD1_k127_4354522_13 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 303.0
HFD1_k127_4354522_14 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 295.0
HFD1_k127_4354522_15 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009767 293.0
HFD1_k127_4354522_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000002445 194.0
HFD1_k127_4354522_17 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000004262 164.0
HFD1_k127_4354522_18 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000000001033 136.0
HFD1_k127_4354522_19 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000383 132.0
HFD1_k127_4354522_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 4.695e-213 694.0
HFD1_k127_4354522_21 phosphorelay signal transduction system K02437 - - 0.000000000000000000000000004002 123.0
HFD1_k127_4354522_22 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000891 87.0
HFD1_k127_4354522_24 12 heme-binding sites - - - 0.00006843 55.0
HFD1_k127_4354522_3 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 3.71e-203 643.0
HFD1_k127_4354522_4 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 556.0
HFD1_k127_4354522_5 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 537.0
HFD1_k127_4354522_6 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 537.0
HFD1_k127_4354522_7 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 475.0
HFD1_k127_4354522_8 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 424.0
HFD1_k127_4354522_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 433.0
HFD1_k127_4360066_0 Amidase K01426 - 3.5.1.4 5.454e-216 686.0
HFD1_k127_4360066_1 peptidyl-tyrosine sulfation - - - 3.553e-213 682.0
HFD1_k127_4360066_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 511.0
HFD1_k127_4360066_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 498.0
HFD1_k127_4360066_4 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 459.0
HFD1_k127_4360066_5 Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 374.0
HFD1_k127_4360066_6 cellulase activity - - - 0.00000000000000000000000000000000000002099 157.0
HFD1_k127_4360066_7 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000008876 150.0
HFD1_k127_4360066_8 Transcriptional regulator - - - 0.0000000000000000001689 97.0
HFD1_k127_4360066_9 domain, Protein K12685,K16785,K16786,K16787 - - 0.00000000000002779 84.0
HFD1_k127_4396119_0 Peptidase dimerisation domain - - - 1.725e-214 677.0
HFD1_k127_4396119_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 473.0
HFD1_k127_4396119_2 Methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000002269 236.0
HFD1_k127_4396119_3 PFAM response regulator receiver - - - 0.0000008969 51.0
HFD1_k127_4396119_4 Enoyl-(Acyl carrier protein) reductase K04506,K11153,K11161 GO:0001523,GO:0001654,GO:0001754,GO:0003407,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0007275,GO:0007399,GO:0007423,GO:0008106,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009644,GO:0009653,GO:0009887,GO:0009987,GO:0010817,GO:0010842,GO:0016020,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0019866,GO:0022008,GO:0030154,GO:0030182,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0034308,GO:0034754,GO:0042445,GO:0042461,GO:0042462,GO:0042572,GO:0043010,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046530,GO:0048468,GO:0048513,GO:0048592,GO:0048593,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0052650,GO:0055114,GO:0060041,GO:0060042,GO:0065007,GO:0065008,GO:0071704,GO:0090596,GO:1901615 1.1.1.300,2.3.2.27 0.00002443 47.0
HFD1_k127_4538150_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1078.0
HFD1_k127_4538150_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 4.036e-212 687.0
HFD1_k127_4538150_10 Cupredoxin-like domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000003662 123.0
HFD1_k127_4538150_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 423.0
HFD1_k127_4538150_3 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 341.0
HFD1_k127_4538150_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 294.0
HFD1_k127_4538150_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000767 253.0
HFD1_k127_4538150_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000001998 232.0
HFD1_k127_4538150_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000009264 166.0
HFD1_k127_4538150_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000407 149.0
HFD1_k127_4538150_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000003544 128.0
HFD1_k127_4547844_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 442.0
HFD1_k127_4547844_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 324.0
HFD1_k127_4547844_2 Zinc carboxypeptidase K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003923 283.0
HFD1_k127_4547844_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000158 247.0
HFD1_k127_4547844_4 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000009961 159.0
HFD1_k127_4620237_0 Protein of unknown function (DUF3604) - - - 0.0 1024.0
HFD1_k127_4620237_1 Protein of unknown function (DUF3604) - - - 1.457e-244 772.0
HFD1_k127_4620237_2 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 356.0
HFD1_k127_4620237_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001252 237.0
HFD1_k127_4620237_4 HupE / UreJ protein K03192 - - 0.0000000000000000000000000000000000000000000000000000000000006688 232.0
HFD1_k127_4620237_5 HupE / UreJ protein - - - 0.0000000000000000000000000000003668 137.0
HFD1_k127_4620237_6 - - - - 0.0000000000001107 79.0
HFD1_k127_4620237_7 Domain of unknown function (DUF3943) - - - 0.00000000461 63.0
HFD1_k127_4713398_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.043e-240 758.0
HFD1_k127_4713398_1 Involved in the tonB-independent uptake of proteins - - - 4.373e-203 661.0
HFD1_k127_4713398_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000001579 202.0
HFD1_k127_4713398_11 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000008049 156.0
HFD1_k127_4713398_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000008007 160.0
HFD1_k127_4713398_13 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000002358 99.0
HFD1_k127_4713398_14 Belongs to the 'phage' integrase family - - - 0.0000001375 64.0
HFD1_k127_4713398_16 Protein of unknown function, DUF255 - - - 0.000009409 57.0
HFD1_k127_4713398_2 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 630.0
HFD1_k127_4713398_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 513.0
HFD1_k127_4713398_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 478.0
HFD1_k127_4713398_5 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 459.0
HFD1_k127_4713398_6 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 392.0
HFD1_k127_4713398_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 367.0
HFD1_k127_4713398_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001456 234.0
HFD1_k127_4713398_9 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000005355 234.0
HFD1_k127_4718728_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 422.0
HFD1_k127_4718728_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 323.0
HFD1_k127_4718728_2 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001648 268.0
HFD1_k127_4718728_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000002477 213.0
HFD1_k127_4718728_4 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000005792 172.0
HFD1_k127_4718728_5 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000000000000002287 148.0
HFD1_k127_4718728_6 protein import - - - 0.0000000003439 73.0
HFD1_k127_4875858_0 low molecular weight K03741 - 1.20.4.1 0.0000000000000000000000001432 114.0
HFD1_k127_4875858_1 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000001174 78.0
HFD1_k127_4875858_2 Metallo-beta-lactamase superfamily - - - 0.000003978 51.0
HFD1_k127_4883914_0 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 340.0
HFD1_k127_4883914_1 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002088 273.0
HFD1_k127_4883914_10 Tetratricopeptide repeat - - - 0.00008035 55.0
HFD1_k127_4883914_11 - - - - 0.0006965 52.0
HFD1_k127_4883914_2 heme binding - - - 0.00000000000000000000000000000000000000000000000046 199.0
HFD1_k127_4883914_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000001195 132.0
HFD1_k127_4883914_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000008511 136.0
HFD1_k127_4883914_5 - - - - 0.000000000000000000004698 109.0
HFD1_k127_4883914_7 DNA-templated transcription, initiation K03088 - - 0.0000003298 60.0
HFD1_k127_4883914_8 Belongs to the peptidase S8 family - - - 0.000001013 61.0
HFD1_k127_4883914_9 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.00007388 50.0
HFD1_k127_4887338_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 545.0
HFD1_k127_4887338_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 547.0
HFD1_k127_4887338_10 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000002192 233.0
HFD1_k127_4887338_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000002091 201.0
HFD1_k127_4887338_12 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000106 194.0
HFD1_k127_4887338_13 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000008553 171.0
HFD1_k127_4887338_14 Oxidoreductase NAD-binding domain K02823 - - 0.000000000000000000000000000000000000000001164 166.0
HFD1_k127_4887338_15 Short-chain dehydrogenase reductase SDR K07535 - - 0.000000000000000000000000000000000000000005327 178.0
HFD1_k127_4887338_16 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000001646 153.0
HFD1_k127_4887338_17 - - - - 0.00000000000000000000000000000000001222 150.0
HFD1_k127_4887338_18 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000002532 144.0
HFD1_k127_4887338_19 Hfq protein - - - 0.00000000000000000000000000000634 122.0
HFD1_k127_4887338_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 456.0
HFD1_k127_4887338_20 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000167 132.0
HFD1_k127_4887338_21 cheY-homologous receiver domain - - - 0.00000000000000000000000001165 114.0
HFD1_k127_4887338_22 esterase - - - 0.00000000000000000000000001818 120.0
HFD1_k127_4887338_23 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000004285 98.0
HFD1_k127_4887338_24 - - - - 0.00000000000002807 78.0
HFD1_k127_4887338_25 peptidase inhibitor activity - - - 0.000000000001353 79.0
HFD1_k127_4887338_27 - - - - 0.000000005262 59.0
HFD1_k127_4887338_28 - - - - 0.0000001578 61.0
HFD1_k127_4887338_3 Bacterial sugar transferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 415.0
HFD1_k127_4887338_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 415.0
HFD1_k127_4887338_5 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 394.0
HFD1_k127_4887338_6 Domain of unknown function (DUF1972) K12996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 355.0
HFD1_k127_4887338_7 Dihydroorotate dehydrogenase K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 328.0
HFD1_k127_4887338_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001759 262.0
HFD1_k127_4887338_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000007217 237.0
HFD1_k127_4899750_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 7.018e-275 865.0
HFD1_k127_4899750_1 PFAM Type II secretion system protein E K02652 - - 3.258e-216 683.0
HFD1_k127_4899750_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
HFD1_k127_4899750_11 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003103 301.0
HFD1_k127_4899750_12 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003242 286.0
HFD1_k127_4899750_13 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003298 285.0
HFD1_k127_4899750_14 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000001597 261.0
HFD1_k127_4899750_15 molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000008682 260.0
HFD1_k127_4899750_16 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000009197 259.0
HFD1_k127_4899750_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000002674 255.0
HFD1_k127_4899750_18 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000001032 220.0
HFD1_k127_4899750_19 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000001276 214.0
HFD1_k127_4899750_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 5.809e-209 668.0
HFD1_k127_4899750_20 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000001659 194.0
HFD1_k127_4899750_21 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000003572 200.0
HFD1_k127_4899750_22 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000008413 196.0
HFD1_k127_4899750_23 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000001432 185.0
HFD1_k127_4899750_24 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000005416 178.0
HFD1_k127_4899750_25 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000007896 176.0
HFD1_k127_4899750_26 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000002658 163.0
HFD1_k127_4899750_27 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000524 168.0
HFD1_k127_4899750_28 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000001292 147.0
HFD1_k127_4899750_29 prepilin-type N-terminal cleavage methylation K02456 - - 0.00000000000000000000000000000000994 133.0
HFD1_k127_4899750_3 Involved in the tonB-independent uptake of proteins - - - 1.464e-198 648.0
HFD1_k127_4899750_30 collagen metabolic process - - - 0.000000000000000000000000000001943 131.0
HFD1_k127_4899750_31 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000001046 121.0
HFD1_k127_4899750_32 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000002396 113.0
HFD1_k127_4899750_33 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000005428 105.0
HFD1_k127_4899750_34 Putative regulatory protein - - - 0.0000000000000000146 91.0
HFD1_k127_4899750_35 Adenylate cyclase - - - 0.0000000000000000542 89.0
HFD1_k127_4899750_36 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000003103 80.0
HFD1_k127_4899750_37 general secretion pathway protein K02456,K02650 - - 0.0000000001016 73.0
HFD1_k127_4899750_38 Pilus assembly protein K02662 - - 0.0000000003693 70.0
HFD1_k127_4899750_39 heat shock protein binding K05516 - - 0.000000002889 68.0
HFD1_k127_4899750_4 Involved in the tonB-independent uptake of proteins - - - 6.838e-196 644.0
HFD1_k127_4899750_40 Serine aminopeptidase, S33 - - - 0.0000001625 64.0
HFD1_k127_4899750_41 PFAM Fimbrial assembly family protein K02663 - - 0.000007953 60.0
HFD1_k127_4899750_42 general secretion pathway protein D K02453 - - 0.0002819 51.0
HFD1_k127_4899750_5 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 540.0
HFD1_k127_4899750_6 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 456.0
HFD1_k127_4899750_7 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 446.0
HFD1_k127_4899750_8 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 381.0
HFD1_k127_4899750_9 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 340.0
HFD1_k127_4918590_0 Flotillin K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 408.0
HFD1_k127_4918590_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 389.0
HFD1_k127_4918590_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000005685 179.0
HFD1_k127_4918590_4 50S ribosomal protein L31 K02909 - - 0.000000001953 63.0
HFD1_k127_4945178_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.394e-227 731.0
HFD1_k127_4945178_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 447.0
HFD1_k127_4945178_2 Protein tyrosine kinase - - - 0.0000000000000000000000001083 116.0
HFD1_k127_5010715_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 371.0
HFD1_k127_5010715_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000007332 173.0
HFD1_k127_5010715_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000871 111.0
HFD1_k127_5010715_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000003585 106.0
HFD1_k127_506759_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1174.0
HFD1_k127_506759_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 8.678e-297 930.0
HFD1_k127_506759_10 COG0076 Glutamate decarboxylase and related PLP-dependent K01593,K13745 - 4.1.1.105,4.1.1.28,4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 396.0
HFD1_k127_506759_11 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 356.0
HFD1_k127_506759_12 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 328.0
HFD1_k127_506759_13 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 324.0
HFD1_k127_506759_14 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 317.0
HFD1_k127_506759_15 NAD dependent epimerase dehydratase family K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 310.0
HFD1_k127_506759_16 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000138 285.0
HFD1_k127_506759_17 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009994 285.0
HFD1_k127_506759_18 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002828 291.0
HFD1_k127_506759_19 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004503 288.0
HFD1_k127_506759_2 Protein kinase domain K12132 - 2.7.11.1 3.378e-209 680.0
HFD1_k127_506759_20 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001157 258.0
HFD1_k127_506759_21 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006567 244.0
HFD1_k127_506759_22 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000002621 240.0
HFD1_k127_506759_23 Amino-transferase class IV K00824,K00826 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21,2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000222 241.0
HFD1_k127_506759_24 PFAM response regulator receiver K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000003552 233.0
HFD1_k127_506759_25 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000004608 237.0
HFD1_k127_506759_26 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001698 222.0
HFD1_k127_506759_27 protein histidine kinase activity K02484,K07640,K07643,K07645,K07649,K19609 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001971 199.0
HFD1_k127_506759_28 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000001574 203.0
HFD1_k127_506759_29 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000005756 186.0
HFD1_k127_506759_3 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 551.0
HFD1_k127_506759_30 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000005802 202.0
HFD1_k127_506759_31 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000009437 196.0
HFD1_k127_506759_32 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000002058 177.0
HFD1_k127_506759_33 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000002667 182.0
HFD1_k127_506759_34 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000004204 163.0
HFD1_k127_506759_35 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000001856 151.0
HFD1_k127_506759_36 RNA recognition motif - - - 0.0000000000000000000000000001601 119.0
HFD1_k127_506759_37 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000005445 119.0
HFD1_k127_506759_38 Cupin domain - - - 0.00000000000000000002242 99.0
HFD1_k127_506759_39 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000616 104.0
HFD1_k127_506759_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 527.0
HFD1_k127_506759_40 peptidoglycan biosynthetic process K03980,K21004 - - 0.000000000000000003638 89.0
HFD1_k127_506759_41 DinB superfamily - - - 0.000000000000000005285 92.0
HFD1_k127_506759_42 protein conserved in bacteria - - - 0.000000000000000007542 89.0
HFD1_k127_506759_43 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000003119 59.0
HFD1_k127_506759_44 Methyltransferase - - - 0.00000005403 64.0
HFD1_k127_506759_45 chlorophyll binding - - - 0.0000002197 64.0
HFD1_k127_506759_47 Virulence factor membrane-bound polymerase, C-terminal K13009 - - 0.0003775 53.0
HFD1_k127_506759_5 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 481.0
HFD1_k127_506759_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 446.0
HFD1_k127_506759_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 425.0
HFD1_k127_506759_8 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 403.0
HFD1_k127_506759_9 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 400.0
HFD1_k127_5122029_0 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 2.079e-282 879.0
HFD1_k127_5122029_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 5.222e-245 791.0
HFD1_k127_5122029_10 Glycoside hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 362.0
HFD1_k127_5122029_11 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 361.0
HFD1_k127_5122029_12 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 331.0
HFD1_k127_5122029_13 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 313.0
HFD1_k127_5122029_14 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 308.0
HFD1_k127_5122029_15 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 305.0
HFD1_k127_5122029_16 PFAM MscS Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001326 256.0
HFD1_k127_5122029_17 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000006749 257.0
HFD1_k127_5122029_18 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000001098 229.0
HFD1_k127_5122029_19 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000002592 199.0
HFD1_k127_5122029_2 beta-lactamase - - - 1.786e-234 754.0
HFD1_k127_5122029_20 Glucosamine-6-phosphate deaminase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000005143 191.0
HFD1_k127_5122029_21 BadF BadG BcrA BcrD - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000001113 191.0
HFD1_k127_5122029_22 Cytochrome c oxidase subunit III - - - 0.00000000000000000000000000000000000000000000004426 179.0
HFD1_k127_5122029_23 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000001056 186.0
HFD1_k127_5122029_24 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000006404 166.0
HFD1_k127_5122029_25 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000004637 158.0
HFD1_k127_5122029_26 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000000000002301 148.0
HFD1_k127_5122029_27 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.000000000000000000000000000000000003614 148.0
HFD1_k127_5122029_28 DinB superfamily - - - 0.0000000000000000000000005474 118.0
HFD1_k127_5122029_29 Thioredoxin-like - - - 0.00000000000000000004949 104.0
HFD1_k127_5122029_3 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 1.634e-210 672.0
HFD1_k127_5122029_30 PFAM Peptidase M20 K01436 - - 0.00005057 48.0
HFD1_k127_5122029_4 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 582.0
HFD1_k127_5122029_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 501.0
HFD1_k127_5122029_6 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 468.0
HFD1_k127_5122029_7 PFAM DAHP synthetase I KDSA K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 467.0
HFD1_k127_5122029_8 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 474.0
HFD1_k127_5122029_9 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 409.0
HFD1_k127_5159354_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 2.578e-194 638.0
HFD1_k127_5159354_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 542.0
HFD1_k127_5159354_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 340.0
HFD1_k127_5159354_3 NUDIX domain - - - 0.000000000000001885 81.0
HFD1_k127_5159354_4 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000001044 73.0
HFD1_k127_5159354_5 pfam nudix - - - 0.0000000009469 65.0
HFD1_k127_522433_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1561.0
HFD1_k127_522433_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 453.0
HFD1_k127_522433_11 Lipid A 3-O-deacylase (PagL) - - - 0.0002651 49.0
HFD1_k127_522433_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 452.0
HFD1_k127_522433_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 439.0
HFD1_k127_522433_4 trimming of terminal mannose on B branch K10085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 328.0
HFD1_k127_522433_5 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000001391 235.0
HFD1_k127_522433_6 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.000000000000000000000000000000000000000000000000000000000000001948 224.0
HFD1_k127_522433_7 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000001087 221.0
HFD1_k127_522433_8 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000000003346 191.0
HFD1_k127_522433_9 Uncharacterized conserved protein (COG2071) K09166 - - 0.000000000000000000000000000000000000003042 153.0
HFD1_k127_5250524_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1316.0
HFD1_k127_5250524_1 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1060.0
HFD1_k127_5250524_10 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 408.0
HFD1_k127_5250524_11 Associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 356.0
HFD1_k127_5250524_12 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 336.0
HFD1_k127_5250524_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004737 286.0
HFD1_k127_5250524_14 metallochaperone-like domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004047 261.0
HFD1_k127_5250524_15 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001004 252.0
HFD1_k127_5250524_16 - K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000002759 240.0
HFD1_k127_5250524_17 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000483 248.0
HFD1_k127_5250524_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001951 236.0
HFD1_k127_5250524_19 surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000005831 231.0
HFD1_k127_5250524_2 Phosphoglucose isomerase K01810 - 5.3.1.9 8.342e-290 896.0
HFD1_k127_5250524_20 XdhC Rossmann domain - - - 0.000000000000000000000000000000000000000000000000000000000000006684 235.0
HFD1_k127_5250524_21 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000002803 184.0
HFD1_k127_5250524_22 MobA-Related Protein K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000001038 187.0
HFD1_k127_5250524_23 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000005045 171.0
HFD1_k127_5250524_24 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000000000000001808 143.0
HFD1_k127_5250524_25 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000005858 126.0
HFD1_k127_5250524_26 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000003627 96.0
HFD1_k127_5250524_27 - - - - 0.00000000000000000007613 97.0
HFD1_k127_5250524_28 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000003518 97.0
HFD1_k127_5250524_29 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000001725 90.0
HFD1_k127_5250524_3 Predicted Permease Membrane Region - - - 1.903e-204 651.0
HFD1_k127_5250524_30 phosphorelay signal transduction system K14987 - - 0.0000000000002487 80.0
HFD1_k127_5250524_4 Fumarase C C-terminus K01744 - 4.3.1.1 1.1e-198 653.0
HFD1_k127_5250524_5 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 534.0
HFD1_k127_5250524_6 Inorganic ion transport and metabolism K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 509.0
HFD1_k127_5250524_7 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 510.0
HFD1_k127_5250524_8 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 440.0
HFD1_k127_5250524_9 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 410.0
HFD1_k127_5252040_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 6.37e-318 1002.0
HFD1_k127_5252040_1 Hydrolase CocE NonD family - - - 5.422e-300 934.0
HFD1_k127_5252040_10 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 418.0
HFD1_k127_5252040_11 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 393.0
HFD1_k127_5252040_12 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 322.0
HFD1_k127_5252040_13 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 332.0
HFD1_k127_5252040_14 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 302.0
HFD1_k127_5252040_15 D-arabinono-1,4-lactone oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001744 308.0
HFD1_k127_5252040_16 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007347 276.0
HFD1_k127_5252040_17 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002284 251.0
HFD1_k127_5252040_18 COG0642 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003513 255.0
HFD1_k127_5252040_19 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000003677 220.0
HFD1_k127_5252040_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 2.069e-248 773.0
HFD1_k127_5252040_20 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000004693 229.0
HFD1_k127_5252040_21 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000005517 197.0
HFD1_k127_5252040_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000009776 194.0
HFD1_k127_5252040_23 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000005756 184.0
HFD1_k127_5252040_24 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000008587 183.0
HFD1_k127_5252040_25 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000986 191.0
HFD1_k127_5252040_26 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000000000001982 162.0
HFD1_k127_5252040_27 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000001964 151.0
HFD1_k127_5252040_28 endonuclease III K01247 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.0000000000000000000000000000000000001577 154.0
HFD1_k127_5252040_29 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000007609 147.0
HFD1_k127_5252040_3 MacB-like periplasmic core domain - - - 9.478e-246 783.0
HFD1_k127_5252040_30 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000001572 132.0
HFD1_k127_5252040_31 DoxX K15977 - - 0.00000000000000000000000000000000524 138.0
HFD1_k127_5252040_32 oxidation-reduction process - - - 0.000000000000000000000000000005129 134.0
HFD1_k127_5252040_33 PFAM YCII-related - - - 0.00000000000000000000000000008032 120.0
HFD1_k127_5252040_34 Tetratricopeptide repeat - - - 0.00000000000000000000009189 102.0
HFD1_k127_5252040_35 - - - - 0.00000000000000000005004 92.0
HFD1_k127_5252040_36 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000003882 83.0
HFD1_k127_5252040_37 peptidase - - - 0.0000002606 56.0
HFD1_k127_5252040_38 - - - - 0.00000858 54.0
HFD1_k127_5252040_4 transferase activity, transferring acyl groups K14658,K17840,K18815 - 2.3.1.59,2.3.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 626.0
HFD1_k127_5252040_5 DNA primase, small subunit K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 584.0
HFD1_k127_5252040_6 ATP dependent DNA ligase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 550.0
HFD1_k127_5252040_7 response to abiotic stimulus K03086,K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 543.0
HFD1_k127_5252040_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 479.0
HFD1_k127_5252040_9 belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 452.0
HFD1_k127_5258011_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 583.0
HFD1_k127_5258011_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 533.0
HFD1_k127_5258011_2 Involved in the tonB-independent uptake of proteins - - - 0.000000002739 59.0
HFD1_k127_539761_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1395.0
HFD1_k127_539761_1 transcription factor binding K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 595.0
HFD1_k127_539761_10 - - - - 0.0000003362 56.0
HFD1_k127_539761_11 - K11477 - - 0.000004319 50.0
HFD1_k127_539761_2 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 501.0
HFD1_k127_539761_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000001456 214.0
HFD1_k127_539761_4 - - - - 0.00000000000000000000000000000000000000000000000000000005349 207.0
HFD1_k127_539761_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000003396 201.0
HFD1_k127_539761_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000004536 172.0
HFD1_k127_539761_7 NADPH-dependent FMN reductase - - - 0.000000000000000000000000001823 112.0
HFD1_k127_539761_8 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000007347 115.0
HFD1_k127_539761_9 Electron transfer DM13 - - - 0.0000000000000000000293 102.0
HFD1_k127_557201_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1319.0
HFD1_k127_557201_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006839 283.0
HFD1_k127_557201_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18302 - - 0.0000000000000000000000000065 114.0
HFD1_k127_5576924_0 - - - - 5.677e-312 971.0
HFD1_k127_5576924_1 Sugar ABC transporter permease K10109,K15770,K15771 - - 1.165e-198 637.0
HFD1_k127_5576924_2 Functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis K10108,K15770 GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006928,GO:0006935,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009593,GO:0009605,GO:0009730,GO:0009743,GO:0009987,GO:0010033,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016477,GO:0030246,GO:0030288,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033036,GO:0033037,GO:0033554,GO:0034285,GO:0034286,GO:0034288,GO:0034289,GO:0040011,GO:0042221,GO:0042330,GO:0042597,GO:0042956,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0048030,GO:0048870,GO:0050896,GO:0051179,GO:0051234,GO:0051606,GO:0051674,GO:0051716,GO:0055052,GO:0060326,GO:0070492,GO:0070887,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901700,GO:1901982,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 538.0
HFD1_k127_5576924_3 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 450.0
HFD1_k127_5576924_4 C-terminal binding-module, SLH-like, of glucodextranase K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 366.0
HFD1_k127_5576924_5 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.000000000000000000000000000000000000000000000000000000002418 213.0
HFD1_k127_5576924_6 Belongs to the ABC transporter superfamily K05816,K10112 - 3.6.3.20 0.000000000000000000005131 94.0
HFD1_k127_5627333_0 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 325.0
HFD1_k127_5627333_1 PFAM Major Facilitator Superfamily - - - 0.0000000005405 62.0
HFD1_k127_5668305_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000001662 193.0
HFD1_k127_5668305_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000001459 167.0
HFD1_k127_5668305_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000002614 137.0
HFD1_k127_5668305_3 PA14 K08738 - - 0.000000000000003654 90.0
HFD1_k127_5669372_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 7.621e-259 824.0
HFD1_k127_5669372_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.727e-252 808.0
HFD1_k127_5669372_10 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000002451 70.0
HFD1_k127_5669372_11 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000006211 52.0
HFD1_k127_5669372_12 Belongs to the 'phage' integrase family - - - 0.0005003 45.0
HFD1_k127_5669372_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 620.0
HFD1_k127_5669372_3 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 542.0
HFD1_k127_5669372_4 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 385.0
HFD1_k127_5669372_5 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001484 266.0
HFD1_k127_5669372_6 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003317 238.0
HFD1_k127_5669372_7 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000004476 173.0
HFD1_k127_5669372_8 nuclease activity - - - 0.0000000000000000000000000000000002898 138.0
HFD1_k127_5669372_9 thiolester hydrolase activity K06889 - - 0.00000000000000000001661 104.0
HFD1_k127_5679026_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 426.0
HFD1_k127_5679026_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 284.0
HFD1_k127_5679026_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000003869 219.0
HFD1_k127_5688451_0 peptidase K01415,K07386 - 3.4.24.71 5.661e-300 934.0
HFD1_k127_5688451_1 Beta-lactamase class C - - - 1.856e-249 789.0
HFD1_k127_5688451_10 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000001559 247.0
HFD1_k127_5688451_11 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000003191 234.0
HFD1_k127_5688451_12 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002707 226.0
HFD1_k127_5688451_13 glutamate-cysteine ligase activity K06048 GO:0003674,GO:0003824,GO:0016874,GO:0016879 - 0.000000000000000000000000000000000000000000000000000000000000002202 238.0
HFD1_k127_5688451_14 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000007873 216.0
HFD1_k127_5688451_15 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000002459 216.0
HFD1_k127_5688451_16 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000002756 204.0
HFD1_k127_5688451_17 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000005285 174.0
HFD1_k127_5688451_18 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000006143 175.0
HFD1_k127_5688451_19 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000000000005982 169.0
HFD1_k127_5688451_2 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 502.0
HFD1_k127_5688451_20 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.000000000000000000000000000000000000000000582 159.0
HFD1_k127_5688451_21 NTPase - - - 0.000000000000000000000000000000000000006071 151.0
HFD1_k127_5688451_22 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000005328 142.0
HFD1_k127_5688451_23 DinB family - - - 0.000000000000000000000000000000000002623 145.0
HFD1_k127_5688451_24 cell septum assembly - - - 0.00000000000000000000000000000003527 142.0
HFD1_k127_5688451_25 Alkylmercury lyase - - - 0.000000000000001185 83.0
HFD1_k127_5688451_26 Alkylmercury lyase - - - 0.0000000000006027 71.0
HFD1_k127_5688451_27 Sporulation and spore germination - - - 0.000000000007236 75.0
HFD1_k127_5688451_3 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 502.0
HFD1_k127_5688451_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 419.0
HFD1_k127_5688451_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 409.0
HFD1_k127_5688451_6 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 310.0
HFD1_k127_5688451_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001707 289.0
HFD1_k127_5688451_8 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004504 278.0
HFD1_k127_5688451_9 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008824 248.0
HFD1_k127_5696320_0 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 574.0
HFD1_k127_5696320_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 506.0
HFD1_k127_5696320_10 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.00000000000000000001133 95.0
HFD1_k127_5696320_11 - - - - 0.0000000000806 70.0
HFD1_k127_5696320_2 SMART ATP-binding region, ATPase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 462.0
HFD1_k127_5696320_3 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 449.0
HFD1_k127_5696320_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 449.0
HFD1_k127_5696320_5 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001762 287.0
HFD1_k127_5696320_6 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000006526 243.0
HFD1_k127_5696320_7 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000000000004311 232.0
HFD1_k127_5696320_8 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000002956 212.0
HFD1_k127_5696320_9 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000001376 143.0
HFD1_k127_5712524_0 ABC transporter K06020 - 3.6.3.25 4.039e-250 826.0
HFD1_k127_5712524_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.405e-229 730.0
HFD1_k127_5712524_10 Protein of unknown function (DUF983) - - - 0.000000000000003413 82.0
HFD1_k127_5712524_2 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 332.0
HFD1_k127_5712524_3 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 332.0
HFD1_k127_5712524_4 Pyrroloquinoline quinone biosynthesis protein PqqB K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006726 273.0
HFD1_k127_5712524_5 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
HFD1_k127_5712524_6 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001078 239.0
HFD1_k127_5712524_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000001347 202.0
HFD1_k127_5712524_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000368 165.0
HFD1_k127_5712524_9 Belongs to the UPF0403 family - - - 0.000000000000000000000000000000000001126 159.0
HFD1_k127_5726199_0 helicase activity - - - 6.996e-317 989.0
HFD1_k127_5726199_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.332e-288 909.0
HFD1_k127_5726199_10 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 484.0
HFD1_k127_5726199_11 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 482.0
HFD1_k127_5726199_12 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 447.0
HFD1_k127_5726199_13 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 435.0
HFD1_k127_5726199_14 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 456.0
HFD1_k127_5726199_15 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 410.0
HFD1_k127_5726199_16 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 402.0
HFD1_k127_5726199_17 - K12065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 372.0
HFD1_k127_5726199_18 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 359.0
HFD1_k127_5726199_19 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 352.0
HFD1_k127_5726199_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 4.07e-271 859.0
HFD1_k127_5726199_20 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 355.0
HFD1_k127_5726199_22 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 307.0
HFD1_k127_5726199_23 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 302.0
HFD1_k127_5726199_24 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 301.0
HFD1_k127_5726199_25 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000221 313.0
HFD1_k127_5726199_26 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001891 290.0
HFD1_k127_5726199_27 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001742 282.0
HFD1_k127_5726199_28 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003649 278.0
HFD1_k127_5726199_29 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009826 267.0
HFD1_k127_5726199_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.06e-234 732.0
HFD1_k127_5726199_30 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004001 265.0
HFD1_k127_5726199_31 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000002062 255.0
HFD1_k127_5726199_32 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000006402 258.0
HFD1_k127_5726199_33 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009347 249.0
HFD1_k127_5726199_34 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001267 245.0
HFD1_k127_5726199_35 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000001386 252.0
HFD1_k127_5726199_36 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000005234 238.0
HFD1_k127_5726199_37 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000002279 233.0
HFD1_k127_5726199_38 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000005367 245.0
HFD1_k127_5726199_39 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000004732 232.0
HFD1_k127_5726199_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.654e-231 727.0
HFD1_k127_5726199_40 Proteasome subunit K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000001992 227.0
HFD1_k127_5726199_41 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway - - - 0.00000000000000000000000000000000000000000000000000000000125 208.0
HFD1_k127_5726199_42 receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000004281 223.0
HFD1_k127_5726199_43 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000001241 208.0
HFD1_k127_5726199_44 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000003337 202.0
HFD1_k127_5726199_45 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000001249 201.0
HFD1_k127_5726199_46 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000006955 192.0
HFD1_k127_5726199_47 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000001519 189.0
HFD1_k127_5726199_48 DinB family - - - 0.0000000000000000000000000000000000000000000001319 172.0
HFD1_k127_5726199_49 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000004927 183.0
HFD1_k127_5726199_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.184e-229 737.0
HFD1_k127_5726199_50 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000006364 170.0
HFD1_k127_5726199_51 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000178 156.0
HFD1_k127_5726199_52 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000005393 151.0
HFD1_k127_5726199_53 Radical SAM superfamily - - - 0.0000000000000000000000000000000007456 147.0
HFD1_k127_5726199_54 TonB-dependent receptor K02014,K16087 - - 0.00000000000000000000000000000005963 145.0
HFD1_k127_5726199_55 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.000000000000000000000000000171 134.0
HFD1_k127_5726199_56 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000001285 126.0
HFD1_k127_5726199_57 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000004714 124.0
HFD1_k127_5726199_58 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000003461 113.0
HFD1_k127_5726199_59 Tetratricopeptide repeat - - - 0.000000000000000000000005814 111.0
HFD1_k127_5726199_6 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 605.0
HFD1_k127_5726199_60 Polymer-forming cytoskeletal - - - 0.00000000000000000000000762 115.0
HFD1_k127_5726199_62 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000009296 100.0
HFD1_k127_5726199_63 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000000001231 110.0
HFD1_k127_5726199_64 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000002871 95.0
HFD1_k127_5726199_65 - - - - 0.0000000000000000001734 96.0
HFD1_k127_5726199_67 Fibronectin type III domain protein - - - 0.0000000000000000004619 100.0
HFD1_k127_5726199_69 Glycosyl transferase family 2 - - - 0.0000000000000002314 91.0
HFD1_k127_5726199_7 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 575.0
HFD1_k127_5726199_70 ubiE/COQ5 methyltransferase family - - - 0.00000000000001047 83.0
HFD1_k127_5726199_71 Protein of unknown function (DUF1573) - - - 0.00000000000003569 85.0
HFD1_k127_5726199_72 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000001716 77.0
HFD1_k127_5726199_73 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000004469 69.0
HFD1_k127_5726199_74 Peptidase family M23 K21472 - - 0.000000000003702 66.0
HFD1_k127_5726199_76 Peptidase, S41 - - - 0.00000007239 62.0
HFD1_k127_5726199_77 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000007979 63.0
HFD1_k127_5726199_78 - - - - 0.0000002212 64.0
HFD1_k127_5726199_79 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000001115 56.0
HFD1_k127_5726199_8 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 526.0
HFD1_k127_5726199_80 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00001029 55.0
HFD1_k127_5726199_81 Belongs to the arylamine N-acetyltransferase family K00622 - 2.3.1.5 0.00003364 56.0
HFD1_k127_5726199_82 Protein of unknown function (DUF3052) - - - 0.0001796 50.0
HFD1_k127_5726199_9 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 532.0
HFD1_k127_575845_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 410.0
HFD1_k127_575845_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 355.0
HFD1_k127_575845_10 domain protein - - - 0.0000000000000000002347 104.0
HFD1_k127_575845_11 DNA polymerase III (delta' subunit) K02340 - 2.7.7.7 0.000003541 59.0
HFD1_k127_575845_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000003734 222.0
HFD1_k127_575845_3 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000002909 196.0
HFD1_k127_575845_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000003053 135.0
HFD1_k127_575845_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000006092 140.0
HFD1_k127_575845_6 metallopeptidase activity - - - 0.00000000000000000000000000002373 121.0
HFD1_k127_575845_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000001085 114.0
HFD1_k127_575845_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000001953 108.0
HFD1_k127_575845_9 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000009854 94.0
HFD1_k127_5783312_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 489.0
HFD1_k127_5783312_1 Arsenical pump membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 368.0
HFD1_k127_5783312_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000007622 251.0
HFD1_k127_5783312_3 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000751 152.0
HFD1_k127_5783312_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000002282 87.0
HFD1_k127_5803985_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000003056 228.0
HFD1_k127_5803985_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000003984 186.0
HFD1_k127_5803985_2 PFAM AhpC TSA family - - - 0.0000000000000000000003479 111.0
HFD1_k127_5805950_0 PFAM BNR Asp-box repeat - - - 3.695e-271 869.0
HFD1_k127_5805950_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 590.0
HFD1_k127_5805950_10 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000002242 191.0
HFD1_k127_5805950_11 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000001642 189.0
HFD1_k127_5805950_12 TatD family K03424 - - 0.000000000000000000000000000000000000000001439 162.0
HFD1_k127_5805950_13 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000006132 156.0
HFD1_k127_5805950_14 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000002381 145.0
HFD1_k127_5805950_15 STAS domain K04749 - - 0.000000000000000000000000000000005176 132.0
HFD1_k127_5805950_16 Zn peptidase - - - 0.00000000000000000000000000001521 132.0
HFD1_k127_5805950_17 TonB-dependent Receptor Plug K02014,K15721 - - 0.0000000000000000000000002627 123.0
HFD1_k127_5805950_18 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000003024 117.0
HFD1_k127_5805950_19 Regulatory protein MarR - - - 0.00000000000000000000002182 108.0
HFD1_k127_5805950_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 430.0
HFD1_k127_5805950_20 Protein of unknown function (DUF2905) - - - 0.00000000000000006554 82.0
HFD1_k127_5805950_22 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000002482 68.0
HFD1_k127_5805950_23 Bacterial antitoxin of type II TA system, VapB - - - 0.000000001775 61.0
HFD1_k127_5805950_25 CAAX protease self-immunity K07052 - - 0.0001967 53.0
HFD1_k127_5805950_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 382.0
HFD1_k127_5805950_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 362.0
HFD1_k127_5805950_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 306.0
HFD1_k127_5805950_6 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 306.0
HFD1_k127_5805950_7 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 295.0
HFD1_k127_5805950_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007417 229.0
HFD1_k127_5805950_9 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003887 230.0
HFD1_k127_5826574_0 Dehydrogenase E1 component K11381 - 1.2.4.4 2.295e-315 978.0
HFD1_k127_5826574_1 ERAP1-like C-terminal domain K01263 - 3.4.11.14 2.413e-235 760.0
HFD1_k127_5826574_10 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000004294 161.0
HFD1_k127_5826574_11 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000002244 162.0
HFD1_k127_5826574_12 PFAM response regulator receiver K07657 - - 0.00000000000000000000000001358 126.0
HFD1_k127_5826574_13 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000002976 81.0
HFD1_k127_5826574_14 PspC domain protein K03973 - - 0.00000000000007947 79.0
HFD1_k127_5826574_15 L,D-transpeptidase catalytic domain - - - 0.000000002417 68.0
HFD1_k127_5826574_16 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000001644 55.0
HFD1_k127_5826574_17 LTXXQ motif family protein - - - 0.0001013 51.0
HFD1_k127_5826574_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001621 276.0
HFD1_k127_5826574_3 Peptidase M15 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004033 269.0
HFD1_k127_5826574_4 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007017 240.0
HFD1_k127_5826574_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000001274 216.0
HFD1_k127_5826574_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000007956 219.0
HFD1_k127_5826574_7 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000000000000000000009572 213.0
HFD1_k127_5826574_8 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000003944 194.0
HFD1_k127_5826574_9 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000003827 179.0
HFD1_k127_5831624_0 Involved in the tonB-independent uptake of proteins - - - 2.115e-202 664.0
HFD1_k127_5831624_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 557.0
HFD1_k127_5831624_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 480.0
HFD1_k127_5831624_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000152 213.0
HFD1_k127_5831624_4 Protein tyrosine kinase - - - 0.00000000000000000000000000009311 117.0
HFD1_k127_5841372_0 Sortilin, neurotensin receptor 3, - - - 0.0 1241.0
HFD1_k127_5841372_1 Fungalysin metallopeptidase (M36) - - - 5.505e-243 801.0
HFD1_k127_5841372_10 Mo-co oxidoreductase dimerisation domain K00387 - 1.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 301.0
HFD1_k127_5841372_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 301.0
HFD1_k127_5841372_12 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 293.0
HFD1_k127_5841372_13 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003967 290.0
HFD1_k127_5841372_14 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009507 270.0
HFD1_k127_5841372_15 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001116 247.0
HFD1_k127_5841372_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002507 237.0
HFD1_k127_5841372_17 - - - - 0.00000000000000000000000000000000000000000000000000000000002519 214.0
HFD1_k127_5841372_18 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000000000000886 209.0
HFD1_k127_5841372_19 Protein of unknown function (DUF1211) - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000002659 209.0
HFD1_k127_5841372_2 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 8.076e-199 634.0
HFD1_k127_5841372_20 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000002785 198.0
HFD1_k127_5841372_21 - - - - 0.000000000000000000000000000000000000000000000006907 185.0
HFD1_k127_5841372_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000001343 186.0
HFD1_k127_5841372_23 phosphorelay signal transduction system - - - 0.00000000000000000000000000003904 123.0
HFD1_k127_5841372_24 - - - - 0.00000000000000000000009056 104.0
HFD1_k127_5841372_25 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000002672 100.0
HFD1_k127_5841372_26 - - - - 0.0000000000000000002904 102.0
HFD1_k127_5841372_28 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000008396 91.0
HFD1_k127_5841372_29 hydroperoxide reductase activity - - - 0.000000000000002994 78.0
HFD1_k127_5841372_3 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 600.0
HFD1_k127_5841372_30 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.000000000000749 76.0
HFD1_k127_5841372_31 peptidyl-tyrosine sulfation - - - 0.00000001973 62.0
HFD1_k127_5841372_33 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.0000002047 62.0
HFD1_k127_5841372_34 PFAM Na-Ca exchanger integrin-beta4 - - - 0.0000005488 59.0
HFD1_k127_5841372_35 Thioredoxin-like - - - 0.000002326 51.0
HFD1_k127_5841372_36 Belongs to the glycosyl hydrolase family 6 - - - 0.0003387 54.0
HFD1_k127_5841372_37 - - - - 0.0004168 51.0
HFD1_k127_5841372_4 Aldo Keto reductase K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 458.0
HFD1_k127_5841372_5 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 451.0
HFD1_k127_5841372_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 396.0
HFD1_k127_5841372_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 411.0
HFD1_k127_5841372_8 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 400.0
HFD1_k127_5841372_9 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 366.0
HFD1_k127_5895518_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.706e-283 888.0
HFD1_k127_5895518_1 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 1.234e-265 823.0
HFD1_k127_5895518_10 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 429.0
HFD1_k127_5895518_11 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 408.0
HFD1_k127_5895518_12 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 393.0
HFD1_k127_5895518_13 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 387.0
HFD1_k127_5895518_14 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 389.0
HFD1_k127_5895518_15 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 375.0
HFD1_k127_5895518_16 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 383.0
HFD1_k127_5895518_17 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 359.0
HFD1_k127_5895518_18 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 371.0
HFD1_k127_5895518_19 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 347.0
HFD1_k127_5895518_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.965e-248 790.0
HFD1_k127_5895518_20 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 301.0
HFD1_k127_5895518_21 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 301.0
HFD1_k127_5895518_22 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 300.0
HFD1_k127_5895518_23 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006537 283.0
HFD1_k127_5895518_24 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005403 268.0
HFD1_k127_5895518_25 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001645 256.0
HFD1_k127_5895518_26 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000001377 262.0
HFD1_k127_5895518_27 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002037 265.0
HFD1_k127_5895518_28 electron transport chain K00347,K03614 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000007391 228.0
HFD1_k127_5895518_29 TIGRFAM FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000000001862 200.0
HFD1_k127_5895518_3 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 7.639e-224 722.0
HFD1_k127_5895518_30 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000008605 200.0
HFD1_k127_5895518_31 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000519 204.0
HFD1_k127_5895518_32 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000428 183.0
HFD1_k127_5895518_33 TIGRFAM SUF system FeS K04488 - - 0.0000000000000000000000000000000000000000000000001365 194.0
HFD1_k127_5895518_34 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000002612 171.0
HFD1_k127_5895518_35 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000006197 163.0
HFD1_k127_5895518_36 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000008021 151.0
HFD1_k127_5895518_37 - - - - 0.000000000000000000000000000000000000005011 151.0
HFD1_k127_5895518_38 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000001382 140.0
HFD1_k127_5895518_39 glyoxalase III activity - - - 0.000000000000000000000000000000001418 139.0
HFD1_k127_5895518_4 PFAM peptidase M13 K07386 - - 6.3e-220 702.0
HFD1_k127_5895518_40 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K01560 - 3.8.1.2 0.0000000000000000000000000006545 122.0
HFD1_k127_5895518_41 Haem-degrading - - - 0.0000000000000000000000000006841 131.0
HFD1_k127_5895518_42 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000001023 129.0
HFD1_k127_5895518_43 RNA recognition motif - - - 0.0000000000000000000000002033 114.0
HFD1_k127_5895518_44 TM2 domain - - - 0.000000000000000000000613 97.0
HFD1_k127_5895518_45 Acetamidase/Formamidase family - - - 0.00000000000000003888 91.0
HFD1_k127_5895518_47 YCII-related domain K09780 - - 0.0000000000000297 85.0
HFD1_k127_5895518_48 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000009812 85.0
HFD1_k127_5895518_49 PFAM thioesterase superfamily protein K07107 - - 0.0000000000004087 75.0
HFD1_k127_5895518_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 2.37e-219 696.0
HFD1_k127_5895518_50 hydrolases or acyltransferases alpha beta hydrolase superfamily - - - 0.00000000002216 75.0
HFD1_k127_5895518_51 PFAM Tetratricopeptide repeat - - - 0.0000002068 63.0
HFD1_k127_5895518_6 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 600.0
HFD1_k127_5895518_7 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 586.0
HFD1_k127_5895518_8 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 492.0
HFD1_k127_5895518_9 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 464.0
HFD1_k127_5900871_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1022.0
HFD1_k127_5900871_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.121e-214 694.0
HFD1_k127_5900871_10 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 351.0
HFD1_k127_5900871_11 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000003194 251.0
HFD1_k127_5900871_12 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000009538 223.0
HFD1_k127_5900871_13 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000007851 213.0
HFD1_k127_5900871_14 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000006818 198.0
HFD1_k127_5900871_15 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000001191 201.0
HFD1_k127_5900871_16 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000002181 197.0
HFD1_k127_5900871_17 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000005102 171.0
HFD1_k127_5900871_18 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000008759 177.0
HFD1_k127_5900871_19 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000001033 169.0
HFD1_k127_5900871_2 Cytochrome c - - - 1.078e-198 640.0
HFD1_k127_5900871_20 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000003862 160.0
HFD1_k127_5900871_21 CcmB protein K02194 - - 0.00000000000000000000000000000000006515 143.0
HFD1_k127_5900871_22 membrane K07152,K08976 - - 0.00000000000000000000000000000000008995 147.0
HFD1_k127_5900871_23 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000008876 145.0
HFD1_k127_5900871_24 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000002472 109.0
HFD1_k127_5900871_25 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000236 109.0
HFD1_k127_5900871_26 MacB-like periplasmic core domain K02004 - - 0.0000000003237 61.0
HFD1_k127_5900871_27 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000001506 70.0
HFD1_k127_5900871_28 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000002466 57.0
HFD1_k127_5900871_29 - - - - 0.00001788 55.0
HFD1_k127_5900871_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 546.0
HFD1_k127_5900871_30 - - - - 0.0008371 48.0
HFD1_k127_5900871_4 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 462.0
HFD1_k127_5900871_5 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 453.0
HFD1_k127_5900871_6 Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007528 455.0
HFD1_k127_5900871_7 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 422.0
HFD1_k127_5900871_8 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 375.0
HFD1_k127_5900871_9 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 355.0
HFD1_k127_5909539_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001864 223.0
HFD1_k127_5909539_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000001575 154.0
HFD1_k127_5909539_2 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000005019 126.0
HFD1_k127_5909539_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000009198 112.0
HFD1_k127_5909539_4 cell septum assembly K02487,K06596,K08372 - - 0.0000000000738 68.0
HFD1_k127_5913447_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.429e-196 635.0
HFD1_k127_5913447_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 471.0
HFD1_k127_5913447_10 PFAM Hly-III family protein K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000333 244.0
HFD1_k127_5913447_11 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000003356 235.0
HFD1_k127_5913447_12 Protein of unknown function (DUF3455) - - - 0.00000000000000000000000000000000000000000000000000000000000437 215.0
HFD1_k127_5913447_13 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001212 208.0
HFD1_k127_5913447_14 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000001941 214.0
HFD1_k127_5913447_15 - - - - 0.00000000000000000000000000000000000006805 152.0
HFD1_k127_5913447_16 - - - - 0.0000000000000000000000000000000000009987 142.0
HFD1_k127_5913447_17 - - - - 0.00000000000000000000000000000004553 135.0
HFD1_k127_5913447_18 Cupin domain - - - 0.0000000000000000000000000001232 121.0
HFD1_k127_5913447_19 - - - - 0.000000000000000000000001751 114.0
HFD1_k127_5913447_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 426.0
HFD1_k127_5913447_20 translation initiation factor activity K06996 - - 0.0000000000000000000000119 105.0
HFD1_k127_5913447_21 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000003321 113.0
HFD1_k127_5913447_22 DinB family - - - 0.0000000000000000002299 94.0
HFD1_k127_5913447_23 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0000000000000000003222 91.0
HFD1_k127_5913447_24 OsmC-like protein - - - 0.0000000000007519 73.0
HFD1_k127_5913447_25 - - - - 0.00000000007587 75.0
HFD1_k127_5913447_26 DinB family - - - 0.0000166 49.0
HFD1_k127_5913447_27 - - - - 0.0001177 54.0
HFD1_k127_5913447_28 DinB family - - - 0.0003329 49.0
HFD1_k127_5913447_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 385.0
HFD1_k127_5913447_4 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 386.0
HFD1_k127_5913447_5 Phosphofructokinase K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 371.0
HFD1_k127_5913447_6 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 339.0
HFD1_k127_5913447_7 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 334.0
HFD1_k127_5913447_8 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 312.0
HFD1_k127_5913447_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007615 262.0
HFD1_k127_5931203_0 SMART Elongator protein 3 MiaB NifB - - - 1.9e-218 687.0
HFD1_k127_5931203_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 4.448e-215 677.0
HFD1_k127_5931203_2 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.055e-201 644.0
HFD1_k127_5931203_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 3.689e-196 627.0
HFD1_k127_5931203_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 412.0
HFD1_k127_5931203_5 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001935 304.0
HFD1_k127_5931203_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001021 251.0
HFD1_k127_5931203_7 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000002699 254.0
HFD1_k127_5931203_8 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000002593 161.0
HFD1_k127_5931203_9 cheY-homologous receiver domain - - - 0.000000000000000000000001568 109.0
HFD1_k127_5985142_0 Glycogen debranching enzyme - - - 0.0 1488.0
HFD1_k127_5985142_1 Protein kinase domain K12132 - 2.7.11.1 6.019e-266 850.0
HFD1_k127_5985142_10 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 404.0
HFD1_k127_5985142_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 381.0
HFD1_k127_5985142_12 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 360.0
HFD1_k127_5985142_13 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 377.0
HFD1_k127_5985142_14 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 372.0
HFD1_k127_5985142_15 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 357.0
HFD1_k127_5985142_16 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 328.0
HFD1_k127_5985142_17 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 331.0
HFD1_k127_5985142_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005476 264.0
HFD1_k127_5985142_19 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 232.0
HFD1_k127_5985142_2 Berberine and berberine like - - - 2.562e-236 740.0
HFD1_k127_5985142_20 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004741 240.0
HFD1_k127_5985142_21 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002587 226.0
HFD1_k127_5985142_22 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000003546 229.0
HFD1_k127_5985142_23 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000004804 222.0
HFD1_k127_5985142_24 PFAM Acetyl-CoA hydrolase transferase K18118 - 2.8.3.18 0.0000000000000000000000000000000000000000000000000000000000002786 213.0
HFD1_k127_5985142_25 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000000000000000000000000000000000000000002667 216.0
HFD1_k127_5985142_26 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000003131 217.0
HFD1_k127_5985142_27 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000003089 204.0
HFD1_k127_5985142_28 - - - - 0.00000000000000000000000000000000000000000000000002861 186.0
HFD1_k127_5985142_29 - - - - 0.00000000000000000000000000000000000000000000000007264 184.0
HFD1_k127_5985142_3 Alpha amylase, catalytic domain - - - 5.861e-231 723.0
HFD1_k127_5985142_30 PFAM Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000001034 175.0
HFD1_k127_5985142_31 MaoC like domain K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000002747 171.0
HFD1_k127_5985142_33 Cupin domain protein - - - 0.00000000000000000000000000000003447 135.0
HFD1_k127_5985142_34 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000005049 122.0
HFD1_k127_5985142_35 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000008814 116.0
HFD1_k127_5985142_36 - - - - 0.0000000000000000000000007905 109.0
HFD1_k127_5985142_37 Yip1 domain - - - 0.000000000000000000001309 103.0
HFD1_k127_5985142_38 - - - - 0.0000000000000000003396 95.0
HFD1_k127_5985142_39 PFAM Tetratricopeptide repeat - - - 0.000000000000001103 91.0
HFD1_k127_5985142_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 631.0
HFD1_k127_5985142_40 - - - - 0.00000000000002158 83.0
HFD1_k127_5985142_41 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000003338 78.0
HFD1_k127_5985142_42 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000005251 74.0
HFD1_k127_5985142_43 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000891 75.0
HFD1_k127_5985142_44 ACT domain - - - 0.0000000006076 68.0
HFD1_k127_5985142_46 SnoaL-like domain - - - 0.000002082 56.0
HFD1_k127_5985142_5 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 566.0
HFD1_k127_5985142_6 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 542.0
HFD1_k127_5985142_7 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 445.0
HFD1_k127_5985142_8 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 448.0
HFD1_k127_5985142_9 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 389.0
HFD1_k127_6195408_0 Helicase K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 450.0
HFD1_k127_6195408_1 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 384.0
HFD1_k127_6195408_2 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 364.0
HFD1_k127_6195408_3 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000005596 151.0
HFD1_k127_6439546_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.147e-282 892.0
HFD1_k127_6439546_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 477.0
HFD1_k127_6439546_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 362.0
HFD1_k127_6439546_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000001034 181.0
HFD1_k127_6440705_0 Prokaryotic cytochrome b561 - - - 0.0 1096.0
HFD1_k127_6440705_1 formate dehydrogenase - - - 1.177e-237 757.0
HFD1_k127_6440705_10 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000001638 213.0
HFD1_k127_6440705_11 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000003073 158.0
HFD1_k127_6440705_12 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000001543 117.0
HFD1_k127_6440705_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000002482 91.0
HFD1_k127_6440705_14 - - - - 0.0000000001888 74.0
HFD1_k127_6440705_2 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 617.0
HFD1_k127_6440705_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 584.0
HFD1_k127_6440705_4 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 549.0
HFD1_k127_6440705_5 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 457.0
HFD1_k127_6440705_6 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 416.0
HFD1_k127_6440705_7 COG0644 Dehydrogenases (flavoproteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 352.0
HFD1_k127_6440705_8 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 367.0
HFD1_k127_6440705_9 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 330.0
HFD1_k127_6443696_0 Pfam:KaiC K08482 - - 1.272e-199 634.0
HFD1_k127_6443696_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 392.0
HFD1_k127_6443696_2 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 355.0
HFD1_k127_6443696_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000002727 162.0
HFD1_k127_6443696_4 PFAM KaiB domain K08481 - - 0.0000000000000000000000000000000000581 150.0
HFD1_k127_6443696_5 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000001576 112.0
HFD1_k127_6524763_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1285.0
HFD1_k127_6524763_1 Malate synthase K01638 - 2.3.3.9 0.0 1196.0
HFD1_k127_6524763_10 Belongs to the phosphoenolpyruvate carboxykinase (ATP) family K01610 - 4.1.1.49 4.947e-194 617.0
HFD1_k127_6524763_11 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 590.0
HFD1_k127_6524763_12 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 568.0
HFD1_k127_6524763_13 IrrE N-terminal-like domain K07110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 542.0
HFD1_k127_6524763_14 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 512.0
HFD1_k127_6524763_15 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 505.0
HFD1_k127_6524763_16 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 472.0
HFD1_k127_6524763_17 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 480.0
HFD1_k127_6524763_18 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 459.0
HFD1_k127_6524763_19 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 442.0
HFD1_k127_6524763_2 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1172.0
HFD1_k127_6524763_20 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 453.0
HFD1_k127_6524763_21 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 428.0
HFD1_k127_6524763_22 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 411.0
HFD1_k127_6524763_23 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 399.0
HFD1_k127_6524763_24 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 376.0
HFD1_k127_6524763_25 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 373.0
HFD1_k127_6524763_26 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
HFD1_k127_6524763_27 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 380.0
HFD1_k127_6524763_28 abc transporter, ATP-binding protein K01995,K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 372.0
HFD1_k127_6524763_29 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 372.0
HFD1_k127_6524763_3 L-Lactate permease K03303 - - 2.606e-309 956.0
HFD1_k127_6524763_30 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 353.0
HFD1_k127_6524763_31 PFAM Major facilitator superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 365.0
HFD1_k127_6524763_32 MFS/sugar transport protein K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 335.0
HFD1_k127_6524763_33 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 332.0
HFD1_k127_6524763_34 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 335.0
HFD1_k127_6524763_35 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 341.0
HFD1_k127_6524763_36 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 320.0
HFD1_k127_6524763_37 formate dehydrogenase K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 318.0
HFD1_k127_6524763_38 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000125 280.0
HFD1_k127_6524763_39 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005693 276.0
HFD1_k127_6524763_4 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 3.122e-301 944.0
HFD1_k127_6524763_40 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000006207 262.0
HFD1_k127_6524763_41 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004521 259.0
HFD1_k127_6524763_42 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005445 278.0
HFD1_k127_6524763_43 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002626 264.0
HFD1_k127_6524763_44 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005787 263.0
HFD1_k127_6524763_45 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000168 256.0
HFD1_k127_6524763_46 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001353 252.0
HFD1_k127_6524763_47 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000009707 261.0
HFD1_k127_6524763_48 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000002973 243.0
HFD1_k127_6524763_49 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000006807 246.0
HFD1_k127_6524763_5 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 7.206e-275 859.0
HFD1_k127_6524763_50 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000002602 241.0
HFD1_k127_6524763_51 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000003431 246.0
HFD1_k127_6524763_52 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000000001432 217.0
HFD1_k127_6524763_53 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000002084 220.0
HFD1_k127_6524763_54 of the beta-lactamase K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000004822 191.0
HFD1_k127_6524763_55 4-oxalocrotonate tautomerase - - - 0.00000000000000000000000000000000000000000002619 164.0
HFD1_k127_6524763_56 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000002176 166.0
HFD1_k127_6524763_57 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000007494 178.0
HFD1_k127_6524763_58 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000007655 137.0
HFD1_k127_6524763_59 protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000001568 126.0
HFD1_k127_6524763_6 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.565e-234 734.0
HFD1_k127_6524763_60 LysR substrate binding domain - - - 0.000000000000000000000000006521 115.0
HFD1_k127_6524763_61 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000002057 99.0
HFD1_k127_6524763_62 Redoxin - - - 0.000000000000000005439 92.0
HFD1_k127_6524763_63 Protein of unknown function (DUF4230) - - - 0.000000000004026 74.0
HFD1_k127_6524763_64 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.00005974 55.0
HFD1_k127_6524763_65 Malate synthase K01638 - 2.3.3.9 0.00008669 54.0
HFD1_k127_6524763_7 Domain of Unknown Function (DUF748) - - - 6.04e-211 699.0
HFD1_k127_6524763_8 Isocitrate lyase family K01637 - 4.1.3.1 4.554e-210 661.0
HFD1_k127_6524763_9 cluster binding protein K18929 - - 8.495e-209 676.0
HFD1_k127_6549752_0 PFAM Leukotriene A4 hydrolase, C-terminal - - - 5.839e-222 707.0
HFD1_k127_6549752_1 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000001844 206.0
HFD1_k127_6549752_2 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000005642 147.0
HFD1_k127_6557032_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1064.0
HFD1_k127_6557032_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 467.0
HFD1_k127_6557032_10 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000002553 236.0
HFD1_k127_6557032_11 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000001562 214.0
HFD1_k127_6557032_12 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000005258 219.0
HFD1_k127_6557032_13 'glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000005745 212.0
HFD1_k127_6557032_14 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000004166 206.0
HFD1_k127_6557032_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000001291 194.0
HFD1_k127_6557032_16 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000005826 192.0
HFD1_k127_6557032_17 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000002182 196.0
HFD1_k127_6557032_18 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000006947 185.0
HFD1_k127_6557032_19 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000000000000000000004203 184.0
HFD1_k127_6557032_2 Dihydroxyacetone kinase family K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 437.0
HFD1_k127_6557032_20 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000001526 169.0
HFD1_k127_6557032_21 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000000000000000000004093 161.0
HFD1_k127_6557032_22 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000007913 153.0
HFD1_k127_6557032_23 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000002143 154.0
HFD1_k127_6557032_24 cellulose binding - - - 0.000000000000000000000000000000001901 151.0
HFD1_k127_6557032_25 lipase activity K15349 - - 0.000000000000000000000000000000009929 146.0
HFD1_k127_6557032_26 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000001915 139.0
HFD1_k127_6557032_27 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000003295 141.0
HFD1_k127_6557032_28 Peptidase family M23 K21472 - - 0.0000000000000000000000000000128 130.0
HFD1_k127_6557032_29 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000001579 131.0
HFD1_k127_6557032_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 356.0
HFD1_k127_6557032_30 Diguanylate cyclase - - - 0.000000000000000000000000002421 125.0
HFD1_k127_6557032_31 antisigma factor binding - - - 0.0000000000000000000000447 107.0
HFD1_k127_6557032_32 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000005155 106.0
HFD1_k127_6557032_33 methyltransferase activity K15256 - - 0.0000000000000000000001787 114.0
HFD1_k127_6557032_34 COG0470 ATPase involved in DNA replication K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000002336 107.0
HFD1_k127_6557032_35 UPF0761 membrane protein K07058 - - 0.000000000000002476 89.0
HFD1_k127_6557032_36 Acetyltransferase (GNAT) domain - - - 0.000000000002805 80.0
HFD1_k127_6557032_37 - - - - 0.00000000001688 68.0
HFD1_k127_6557032_38 Glycosyl transferase family 2 K07011 - - 0.0000000000354 75.0
HFD1_k127_6557032_39 Domain of unknown function (DUF4410) - - - 0.00000000008648 71.0
HFD1_k127_6557032_4 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 329.0
HFD1_k127_6557032_40 PFAM Glycosyl transferases group 1 - - - 0.000000002467 70.0
HFD1_k127_6557032_41 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000097 66.0
HFD1_k127_6557032_42 Belongs to the UPF0337 (CsbD) family - - - 0.00009515 50.0
HFD1_k127_6557032_43 cell adhesion involved in biofilm formation K02453 - - 0.0005382 51.0
HFD1_k127_6557032_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 308.0
HFD1_k127_6557032_6 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 306.0
HFD1_k127_6557032_7 Sigma-54 interaction domain K02584,K07713,K15836,K21009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001201 293.0
HFD1_k127_6557032_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000008038 269.0
HFD1_k127_6557032_9 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000028 247.0
HFD1_k127_6631013_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 387.0
HFD1_k127_6631013_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 311.0
HFD1_k127_6631013_2 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001103 282.0
HFD1_k127_6631013_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000002474 170.0
HFD1_k127_6631013_4 methyltransferase activity - - - 0.00000000000000000000000000000000009236 146.0
HFD1_k127_6631013_5 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000001083 132.0
HFD1_k127_6631013_6 enzyme binding K00567,K07443 - 2.1.1.63 0.0000000000000000000000000000003074 126.0
HFD1_k127_6631013_7 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000003567 123.0
HFD1_k127_6631013_8 Polysaccharide biosynthesis protein - - - 0.00000000000000000000001546 117.0
HFD1_k127_6631013_9 Glycosyl transferase, family 2 - - - 0.0000000000000000000001099 113.0
HFD1_k127_6741333_0 Peptidase family M48 - - - 0.00000791 55.0
HFD1_k127_6741333_1 oligosaccharyl transferase activity - - - 0.0001871 54.0
HFD1_k127_6755250_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0016829,GO:0016830,GO:0016833 4.1.3.1 0.0 1184.0
HFD1_k127_6755250_1 Involved in the tonB-independent uptake of proteins - - - 5.101e-211 687.0
HFD1_k127_6755250_10 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 368.0
HFD1_k127_6755250_11 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 297.0
HFD1_k127_6755250_12 Alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000126 272.0
HFD1_k127_6755250_13 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000005642 226.0
HFD1_k127_6755250_14 metallopeptidase activity K01993,K13408,K16922 - - 0.0000000000000000000000000000000000000000000000000000000001674 230.0
HFD1_k127_6755250_15 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000003101 208.0
HFD1_k127_6755250_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000000001876 188.0
HFD1_k127_6755250_17 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000171 155.0
HFD1_k127_6755250_18 Thioesterase - - - 0.00000000000000000000000000000001412 130.0
HFD1_k127_6755250_19 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000936 123.0
HFD1_k127_6755250_2 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 7.778e-210 667.0
HFD1_k127_6755250_20 DNA-sulfur modification-associated - - - 0.00000000000000000006741 102.0
HFD1_k127_6755250_21 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000006125 81.0
HFD1_k127_6755250_22 - - - - 0.0000000000002303 75.0
HFD1_k127_6755250_23 Involved in the tonB-independent uptake of proteins - - - 0.0000000001249 63.0
HFD1_k127_6755250_3 CoA binding domain K01905,K22224 - 6.2.1.13 6.312e-197 635.0
HFD1_k127_6755250_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 584.0
HFD1_k127_6755250_5 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 502.0
HFD1_k127_6755250_6 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 473.0
HFD1_k127_6755250_7 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 408.0
HFD1_k127_6755250_8 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 401.0
HFD1_k127_6755250_9 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 401.0
HFD1_k127_6770283_0 Carboxypeptidase regulatory-like domain - - - 1.715e-232 752.0
HFD1_k127_6770283_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.524e-213 683.0
HFD1_k127_6770283_10 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000009088 94.0
HFD1_k127_6770283_11 - - - - 0.000000000000003774 88.0
HFD1_k127_6770283_12 Alg9-like mannosyltransferase family - - - 0.00000000005567 76.0
HFD1_k127_6770283_13 CHAD - - - 0.00000005499 63.0
HFD1_k127_6770283_2 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 416.0
HFD1_k127_6770283_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 322.0
HFD1_k127_6770283_4 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 327.0
HFD1_k127_6770283_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008442 265.0
HFD1_k127_6770283_6 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000001167 196.0
HFD1_k127_6770283_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000006336 186.0
HFD1_k127_6770283_8 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000005886 173.0
HFD1_k127_6770283_9 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000003336 108.0
HFD1_k127_6795947_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1370.0
HFD1_k127_6795947_1 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 529.0
HFD1_k127_6795947_10 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000007966 214.0
HFD1_k127_6795947_11 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000007545 196.0
HFD1_k127_6795947_12 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000002371 182.0
HFD1_k127_6795947_13 VIT family - - - 0.000000000000000000000000000000000000000000000002803 186.0
HFD1_k127_6795947_14 DinB family - - - 0.0000000000000000000000000000000000000000002038 166.0
HFD1_k127_6795947_15 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000001834 164.0
HFD1_k127_6795947_16 outer membrane efflux protein - - - 0.0000000000000000000000000000000000248 155.0
HFD1_k127_6795947_17 MerR, DNA binding - - - 0.000000000000000000000000000000000259 141.0
HFD1_k127_6795947_18 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000000000000000000000000000009077 135.0
HFD1_k127_6795947_19 helix_turn_helix, Lux Regulon - - - 0.00000000000000000002684 106.0
HFD1_k127_6795947_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 507.0
HFD1_k127_6795947_20 - - - - 0.0000000000000000001601 91.0
HFD1_k127_6795947_21 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000001128 70.0
HFD1_k127_6795947_22 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000007725 64.0
HFD1_k127_6795947_23 domain, Protein - - - 0.00000002131 61.0
HFD1_k127_6795947_24 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.0007529 46.0
HFD1_k127_6795947_3 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 441.0
HFD1_k127_6795947_4 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 406.0
HFD1_k127_6795947_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 351.0
HFD1_k127_6795947_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 344.0
HFD1_k127_6795947_7 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 295.0
HFD1_k127_6795947_8 Tricorn protease C1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008854 282.0
HFD1_k127_6795947_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000001291 242.0
HFD1_k127_6811018_0 AAA ATPase domain - - - 2.48e-313 997.0
HFD1_k127_6811018_1 ATP-grasp domain K01905,K22224 - 6.2.1.13 2.151e-284 900.0
HFD1_k127_6811018_2 Involved in the tonB-independent uptake of proteins - - - 9.037e-203 661.0
HFD1_k127_6811018_3 Belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 542.0
HFD1_k127_6811018_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 340.0
HFD1_k127_6811018_5 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001727 248.0
HFD1_k127_6811018_6 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000003774 179.0
HFD1_k127_6811018_7 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000079 160.0
HFD1_k127_6858678_0 Zinc-binding dehydrogenase - - - 0.0000000000002354 69.0
HFD1_k127_6858678_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000004479 70.0
HFD1_k127_6858678_2 Phage integrase family - - - 0.0000006428 62.0
HFD1_k127_6858678_3 Belongs to the 'phage' integrase family - - - 0.0002958 51.0
HFD1_k127_6984556_0 Large extracellular alpha-helical protein - - - 0.0 2068.0
HFD1_k127_6984556_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1112.0
HFD1_k127_6984556_10 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009703 280.0
HFD1_k127_6984556_11 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003858 273.0
HFD1_k127_6984556_12 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000003807 242.0
HFD1_k127_6984556_13 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000037 216.0
HFD1_k127_6984556_14 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000021 195.0
HFD1_k127_6984556_15 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000002401 192.0
HFD1_k127_6984556_16 - - - - 0.000000000000000000000000000000000000000000000001417 199.0
HFD1_k127_6984556_17 DinB family - - - 0.00000000000000000000000000000000000000000000000158 178.0
HFD1_k127_6984556_18 acetyltransferase - - - 0.0000000000000000000000000000000000000000002787 166.0
HFD1_k127_6984556_19 Penicillinase repressor - - - 0.0000000000000000000000000000000000000001261 154.0
HFD1_k127_6984556_2 DEAD DEAH box helicase K03724 - - 5.063e-308 972.0
HFD1_k127_6984556_20 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000009694 153.0
HFD1_k127_6984556_21 DinB family - - - 0.000000000000000000000000000000000007507 143.0
HFD1_k127_6984556_22 photosystem II stabilization - - - 0.00000000000000000000000000000001021 143.0
HFD1_k127_6984556_23 MgtC family K07507 - - 0.0000000000000000000000000006425 118.0
HFD1_k127_6984556_24 - - - - 0.000000000000000000000004926 104.0
HFD1_k127_6984556_25 - - - - 0.000000000000000000000007396 104.0
HFD1_k127_6984556_26 peptidyl-tyrosine sulfation - - - 0.0000001643 65.0
HFD1_k127_6984556_27 DNA uptake protein and related DNA-binding K02237 - - 0.000000193 63.0
HFD1_k127_6984556_28 Protein tyrosine kinase K12132 - 2.7.11.1 0.000005951 60.0
HFD1_k127_6984556_29 peptidyl-tyrosine sulfation - - - 0.0006492 53.0
HFD1_k127_6984556_3 PFAM multicopper oxidase type 2 - - - 9.895e-238 760.0
HFD1_k127_6984556_4 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 441.0
HFD1_k127_6984556_5 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 365.0
HFD1_k127_6984556_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 323.0
HFD1_k127_6984556_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 311.0
HFD1_k127_6984556_8 Allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001717 313.0
HFD1_k127_6984556_9 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002164 279.0
HFD1_k127_7030677_0 cellulose binding - - - 0.0 1223.0
HFD1_k127_7030677_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 321.0
HFD1_k127_7030677_2 competence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001239 232.0
HFD1_k127_7030677_3 PIN domain - - - 0.000000000000000000000000001461 116.0
HFD1_k127_7030677_4 SpoVT / AbrB like domain - - - 0.00000000000006026 75.0
HFD1_k127_7076122_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 8.212e-281 922.0
HFD1_k127_7076122_1 IgA Peptidase M64 - - - 1.325e-221 695.0
HFD1_k127_7076122_10 GIY-YIG catalytic domain - - - 0.00000000000000007842 80.0
HFD1_k127_7076122_11 Serine aminopeptidase, S33 - - - 0.00000000000001511 83.0
HFD1_k127_7076122_12 Forkhead associated domain - - - 0.000000004568 66.0
HFD1_k127_7076122_13 Endonuclease containing a URI domain K07461 - - 0.0000000239 55.0
HFD1_k127_7076122_2 B12 binding domain - - - 1.001e-215 690.0
HFD1_k127_7076122_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 467.0
HFD1_k127_7076122_4 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 307.0
HFD1_k127_7076122_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000789 262.0
HFD1_k127_7076122_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000002362 257.0
HFD1_k127_7076122_7 - - - - 0.000000000000000000000000000000000000000000000000000002431 201.0
HFD1_k127_7076122_8 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000196 109.0
HFD1_k127_7089633_0 PFAM Peptidase S53, propeptide - - - 2.553e-211 687.0
HFD1_k127_7089633_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 388.0
HFD1_k127_7089633_2 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 318.0
HFD1_k127_7089633_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000001409 178.0
HFD1_k127_7089633_4 Protein of unknown function (DUF1349) - - - 0.0000000000000000000001363 115.0
HFD1_k127_7089633_5 methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.000000000000006409 83.0
HFD1_k127_7089633_6 Psort location CytoplasmicMembrane, score - - - 0.00000006967 65.0
HFD1_k127_7089633_7 transferase activity, transferring acyl groups other than amino-acyl groups K13687 GO:0008150,GO:0040007 - 0.0002853 54.0
HFD1_k127_7107860_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000001396 205.0
HFD1_k127_7107860_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000002111 192.0
HFD1_k127_7107860_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000007505 119.0
HFD1_k127_7224545_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.327e-237 757.0
HFD1_k127_7224545_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.251e-219 714.0
HFD1_k127_7224545_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000001339 95.0
HFD1_k127_7224545_11 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000007006 96.0
HFD1_k127_7224545_12 BON domain - - - 0.00000000000002494 83.0
HFD1_k127_7224545_13 Protein of unknown function (DUF503) K09764 - - 0.00000000000003965 76.0
HFD1_k127_7224545_14 energy transducer activity K03832 - - 0.0000003261 62.0
HFD1_k127_7224545_15 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0007654 48.0
HFD1_k127_7224545_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 473.0
HFD1_k127_7224545_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 376.0
HFD1_k127_7224545_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 357.0
HFD1_k127_7224545_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000178 203.0
HFD1_k127_7224545_6 CoA-binding protein K06929 - - 0.000000000000000000000000000000007067 137.0
HFD1_k127_7224545_7 LuxR family transcriptional regulator K03424 - - 0.00000000000000000000000000000003221 128.0
HFD1_k127_7224545_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000005692 123.0
HFD1_k127_7224545_9 Zincin-like metallopeptidase - - - 0.00000000000000000000127 103.0
HFD1_k127_7250644_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.06e-268 852.0
HFD1_k127_7250644_1 Elongation factor G, domain IV K02355 - - 5.552e-205 658.0
HFD1_k127_7250644_10 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001117 278.0
HFD1_k127_7250644_11 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002093 242.0
HFD1_k127_7250644_12 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000343 205.0
HFD1_k127_7250644_13 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000004725 181.0
HFD1_k127_7250644_14 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000000000000000002799 136.0
HFD1_k127_7250644_15 oxidoreductase activity - - - 0.00000000000000000000000000000451 138.0
HFD1_k127_7250644_16 Phage integrase family - - - 0.000000000000000000512 90.0
HFD1_k127_7250644_18 Protein tyrosine kinase K12132 - 2.7.11.1 0.000003223 60.0
HFD1_k127_7250644_19 tetratricopeptide repeat - - - 0.0002861 52.0
HFD1_k127_7250644_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 568.0
HFD1_k127_7250644_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 588.0
HFD1_k127_7250644_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 552.0
HFD1_k127_7250644_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 388.0
HFD1_k127_7250644_6 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 372.0
HFD1_k127_7250644_7 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 355.0
HFD1_k127_7250644_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 313.0
HFD1_k127_7250644_9 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003347 288.0
HFD1_k127_7260771_0 asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 593.0
HFD1_k127_7260771_1 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 538.0
HFD1_k127_7260771_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 357.0
HFD1_k127_7260771_3 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000043 248.0
HFD1_k127_7260771_4 Belongs to the sirtuin family. Class K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009938 259.0
HFD1_k127_7260771_5 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004601 247.0
HFD1_k127_7260771_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000002989 207.0
HFD1_k127_7260771_7 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000000000001631 196.0
HFD1_k127_7260771_8 - - - - 0.000000000000000000000000004349 121.0
HFD1_k127_7260771_9 cog cog0845 K01993 - - 0.00000001288 66.0
HFD1_k127_7276456_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 522.0
HFD1_k127_7276456_1 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000072 264.0
HFD1_k127_7276456_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000003756 79.0
HFD1_k127_7276456_11 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.00000002173 61.0
HFD1_k127_7276456_2 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000001167 239.0
HFD1_k127_7276456_3 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000586 184.0
HFD1_k127_7276456_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000001767 172.0
HFD1_k127_7276456_5 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000002777 177.0
HFD1_k127_7276456_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000004697 169.0
HFD1_k127_7276456_7 MoaC family K03637 - 4.6.1.17 0.000000000000000000000000000000000000004097 156.0
HFD1_k127_7276456_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000007647 109.0
HFD1_k127_7276456_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000001592 100.0
HFD1_k127_7313020_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002638 291.0
HFD1_k127_7313851_0 Protein of unknown function, DUF255 K06888 - - 4.428e-204 656.0
HFD1_k127_7313851_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 465.0
HFD1_k127_7313851_10 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000000000000000000000000000000000000000000001059 213.0
HFD1_k127_7313851_11 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000001703 208.0
HFD1_k127_7313851_12 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000000009261 212.0
HFD1_k127_7313851_13 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000001645 206.0
HFD1_k127_7313851_14 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000001465 201.0
HFD1_k127_7313851_15 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000006138 146.0
HFD1_k127_7313851_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00172,K00441,K03522 - 1.12.98.1,1.2.7.1 0.000000000000000000000005506 111.0
HFD1_k127_7313851_17 Thioredoxin - - - 0.0000000000000000000001185 111.0
HFD1_k127_7313851_18 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000008952 98.0
HFD1_k127_7313851_19 Peptidase M56 - - - 0.00000000000001443 85.0
HFD1_k127_7313851_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 453.0
HFD1_k127_7313851_20 bacteriochlorophyll K04040 - 2.5.1.133,2.5.1.62 0.00000000000129 80.0
HFD1_k127_7313851_21 PFAM DSBA-like thioredoxin domain - - - 0.0000003315 63.0
HFD1_k127_7313851_22 PFAM PBS lyase HEAT domain protein repeat-containing protein K02288 - 4.4.1.32 0.0000008224 61.0
HFD1_k127_7313851_23 Tetratricopeptide repeat - - - 0.0000762 56.0
HFD1_k127_7313851_24 PFAM phosphatidate cytidylyltransferase - - - 0.0001262 54.0
HFD1_k127_7313851_3 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 402.0
HFD1_k127_7313851_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 415.0
HFD1_k127_7313851_5 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 350.0
HFD1_k127_7313851_6 histone deacetylase K11407 - 3.5.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 321.0
HFD1_k127_7313851_7 CoA-transferase activity K01027,K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 313.0
HFD1_k127_7313851_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000006168 236.0
HFD1_k127_7313851_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000001203 240.0
HFD1_k127_7332006_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.012e-202 662.0
HFD1_k127_7332006_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 538.0
HFD1_k127_7332006_10 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 312.0
HFD1_k127_7332006_11 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007682 289.0
HFD1_k127_7332006_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008489 274.0
HFD1_k127_7332006_13 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000006453 265.0
HFD1_k127_7332006_14 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000002583 232.0
HFD1_k127_7332006_15 TIGRFAM Small GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000001356 219.0
HFD1_k127_7332006_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000003509 217.0
HFD1_k127_7332006_17 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000002473 191.0
HFD1_k127_7332006_18 PFAM Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000003357 165.0
HFD1_k127_7332006_19 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000009014 157.0
HFD1_k127_7332006_2 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 509.0
HFD1_k127_7332006_20 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000007685 146.0
HFD1_k127_7332006_21 transglycosylase K08309 - - 0.000000000000000000000000000000000008846 157.0
HFD1_k127_7332006_22 Methyltransferase small domain - - - 0.00000000000000000000000000000000001802 148.0
HFD1_k127_7332006_23 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000009994 132.0
HFD1_k127_7332006_24 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000001467 132.0
HFD1_k127_7332006_25 YqeY-like protein K09117 - - 0.00000000000000000000000000002769 123.0
HFD1_k127_7332006_26 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000005965 120.0
HFD1_k127_7332006_27 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.0000000000000000000000000004343 119.0
HFD1_k127_7332006_28 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.000000000000000000000000002847 124.0
HFD1_k127_7332006_29 PFAM DivIVA family protein K04074 - - 0.0000000000000000000005414 103.0
HFD1_k127_7332006_3 OmpA family K02557,K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 460.0
HFD1_k127_7332006_30 Histidine kinase - - - 0.0000000000000000000008677 104.0
HFD1_k127_7332006_31 protein with SCP PR1 domains - - - 0.00000000000000000001388 102.0
HFD1_k127_7332006_32 YGGT family K02221 - - 0.00000000000000000001592 96.0
HFD1_k127_7332006_33 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002405 91.0
HFD1_k127_7332006_34 protein involved in tolerance to divalent cations K03926 GO:0003674,GO:0005488,GO:0005507,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840 - 0.0000000000000000002048 93.0
HFD1_k127_7332006_35 C4-type zinc ribbon domain K07164 - - 0.0000000000000008316 87.0
HFD1_k127_7332006_36 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000001336 81.0
HFD1_k127_7332006_37 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000000005832 83.0
HFD1_k127_7332006_38 nuclear chromosome segregation - - - 0.0000000000004646 81.0
HFD1_k127_7332006_39 Belongs to the peptidase S8 family - - - 0.00000000001741 76.0
HFD1_k127_7332006_4 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 445.0
HFD1_k127_7332006_40 Belongs to the 'phage' integrase family - - - 0.000000004584 62.0
HFD1_k127_7332006_42 DNA integration - - - 0.0000029 58.0
HFD1_k127_7332006_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 365.0
HFD1_k127_7332006_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 391.0
HFD1_k127_7332006_7 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 368.0
HFD1_k127_7332006_8 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 345.0
HFD1_k127_7332006_9 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 321.0
HFD1_k127_7348304_0 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 466.0
HFD1_k127_7348304_2 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003747 231.0
HFD1_k127_7348304_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000984 105.0
HFD1_k127_7355348_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 533.0
HFD1_k127_7355348_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000003715 160.0
HFD1_k127_7355348_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000001625 154.0
HFD1_k127_7355348_3 Probably functions as a manganese efflux pump - - - 0.00000000000000000003253 106.0
HFD1_k127_7355348_4 - - - - 0.00000000000000005376 93.0
HFD1_k127_7355348_5 ubiE/COQ5 methyltransferase family - - - 0.00000004056 64.0
HFD1_k127_7355348_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000001704 61.0
HFD1_k127_7380748_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 559.0
HFD1_k127_7380748_1 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 430.0
HFD1_k127_7380748_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.000000000000000000000000000000000000003885 149.0
HFD1_k127_7380748_11 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000001263 119.0
HFD1_k127_7380748_12 positive regulation of growth K19687 - - 0.000000000000000000004145 95.0
HFD1_k127_7380748_13 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000001017 108.0
HFD1_k127_7380748_14 PFAM regulatory protein, MerR - - - 0.0000000000000006731 84.0
HFD1_k127_7380748_15 nitric oxide dioxygenase activity - - - 0.00000000000005347 77.0
HFD1_k127_7380748_16 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001964 64.0
HFD1_k127_7380748_2 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 346.0
HFD1_k127_7380748_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 309.0
HFD1_k127_7380748_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 320.0
HFD1_k127_7380748_5 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004565 275.0
HFD1_k127_7380748_6 ABC transporter, (ATP-binding protein) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006839 296.0
HFD1_k127_7380748_7 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000002139 287.0
HFD1_k127_7380748_8 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001762 268.0
HFD1_k127_7380748_9 PFAM Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000303 247.0
HFD1_k127_7382631_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.003e-213 680.0
HFD1_k127_7382631_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 394.0
HFD1_k127_7382631_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 325.0
HFD1_k127_7382631_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005737 289.0
HFD1_k127_7382631_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000001147 185.0
HFD1_k127_7382631_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000006091 146.0
HFD1_k127_7382631_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000002712 92.0
HFD1_k127_7402114_0 Extracellular solute-binding protein K02027 - - 1.404e-226 707.0
HFD1_k127_7402114_1 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 461.0
HFD1_k127_7402114_10 Alpha/beta hydrolase family - - - 0.0000000000000000000000000001484 124.0
HFD1_k127_7402114_11 PFAM EAL domain - - - 0.000000000000000000000001151 118.0
HFD1_k127_7402114_12 AAA ATPase domain - - - 0.0000000000000000008822 91.0
HFD1_k127_7402114_13 - - - - 0.00000000000000002697 84.0
HFD1_k127_7402114_14 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000006731 84.0
HFD1_k127_7402114_15 S4 RNA-binding domain K04762 - - 0.00000000000004848 82.0
HFD1_k127_7402114_16 Winged helix DNA-binding domain - - - 0.00000005482 61.0
HFD1_k127_7402114_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 440.0
HFD1_k127_7402114_3 Binding-protein-dependent transport system inner membrane component K02025,K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 434.0
HFD1_k127_7402114_4 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 322.0
HFD1_k127_7402114_5 peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 293.0
HFD1_k127_7402114_6 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 293.0
HFD1_k127_7402114_7 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000003288 205.0
HFD1_k127_7402114_8 peptidase U32 K08303 - - 0.000000000000000000000000000000000000000005639 167.0
HFD1_k127_7402114_9 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000003149 162.0
HFD1_k127_7414675_0 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000001038 207.0
HFD1_k127_7414675_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000001375 141.0
HFD1_k127_7414675_2 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000001667 99.0
HFD1_k127_7414675_3 Belongs to the universal stress protein A family - - - 0.00004881 55.0
HFD1_k127_7416026_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1247.0
HFD1_k127_7416026_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 8.247e-271 858.0
HFD1_k127_7416026_10 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 529.0
HFD1_k127_7416026_11 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 534.0
HFD1_k127_7416026_12 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 533.0
HFD1_k127_7416026_13 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 502.0
HFD1_k127_7416026_14 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 472.0
HFD1_k127_7416026_15 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 471.0
HFD1_k127_7416026_16 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 460.0
HFD1_k127_7416026_17 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 446.0
HFD1_k127_7416026_18 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 433.0
HFD1_k127_7416026_19 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 417.0
HFD1_k127_7416026_2 Succinyl-CoA ligase like flavodoxin domain - - - 1.102e-270 859.0
HFD1_k127_7416026_20 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 403.0
HFD1_k127_7416026_21 Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 389.0
HFD1_k127_7416026_22 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 368.0
HFD1_k127_7416026_23 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 350.0
HFD1_k127_7416026_24 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 301.0
HFD1_k127_7416026_25 PFAM Rhomboid family protein K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004145 276.0
HFD1_k127_7416026_26 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001166 276.0
HFD1_k127_7416026_27 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000002304 259.0
HFD1_k127_7416026_28 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000001164 249.0
HFD1_k127_7416026_29 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000006708 220.0
HFD1_k127_7416026_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.868e-264 824.0
HFD1_k127_7416026_30 COG1943 Transposase and inactivated derivatives K07491 - - 0.0000000000000000000000000000000000000000000000000000000007022 213.0
HFD1_k127_7416026_31 KR domain - - - 0.000000000000000000000000000000000000000000000000000000002853 210.0
HFD1_k127_7416026_32 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000295 226.0
HFD1_k127_7416026_33 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000000000003957 207.0
HFD1_k127_7416026_34 PFAM glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000004509 196.0
HFD1_k127_7416026_35 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000001189 188.0
HFD1_k127_7416026_36 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000002511 201.0
HFD1_k127_7416026_37 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000122 192.0
HFD1_k127_7416026_38 iron-sulfur cluster assembly K07400 - - 0.00000000000000000000000000000000000000000001638 170.0
HFD1_k127_7416026_39 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000004301 166.0
HFD1_k127_7416026_4 X-Pro dipeptidyl-peptidase (S15 family) - - - 1.44e-229 729.0
HFD1_k127_7416026_40 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000006153 158.0
HFD1_k127_7416026_41 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000001859 142.0
HFD1_k127_7416026_42 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000003029 128.0
HFD1_k127_7416026_43 Universal stress protein family - - - 0.000000000000000000000000000004504 123.0
HFD1_k127_7416026_44 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000004262 125.0
HFD1_k127_7416026_45 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000005773 124.0
HFD1_k127_7416026_46 Biogenesis protein - - - 0.0000000000000000000000000003431 123.0
HFD1_k127_7416026_47 carbon dioxide binding K04653,K04654 - - 0.00000000000000000000000001717 127.0
HFD1_k127_7416026_48 PFAM CBS domain containing protein K07168 - - 0.00000000000000000000000005262 117.0
HFD1_k127_7416026_49 Dodecin K09165 - - 0.000000000000000000000006282 102.0
HFD1_k127_7416026_5 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 4.777e-203 652.0
HFD1_k127_7416026_50 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000001312 119.0
HFD1_k127_7416026_51 nickel cation binding K04651 - - 0.000000000000000000004 97.0
HFD1_k127_7416026_52 CBS domain - - - 0.00000000000000000005992 98.0
HFD1_k127_7416026_53 - - - - 0.0000000000000000001509 100.0
HFD1_k127_7416026_54 Protein of unknown function (DUF962) - - - 0.0000000000000000007368 92.0
HFD1_k127_7416026_55 Bacterial PH domain K08981 - - 0.00000000000000001204 93.0
HFD1_k127_7416026_56 Heavy-metal resistance - - - 0.0000000000000001864 89.0
HFD1_k127_7416026_57 Putative phosphatase (DUF442) - - - 0.0000000000000003983 85.0
HFD1_k127_7416026_58 CBS domain containing protein - - - 0.000000000000235 79.0
HFD1_k127_7416026_59 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000001648 64.0
HFD1_k127_7416026_6 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 595.0
HFD1_k127_7416026_60 Family of unknown function (DUF5335) - - - 0.00000000004386 70.0
HFD1_k127_7416026_61 Universal stress protein family - - - 0.0000000007877 70.0
HFD1_k127_7416026_62 Universal stress protein - - - 0.00000005575 64.0
HFD1_k127_7416026_63 mRNA catabolic process K06950 - - 0.000001113 59.0
HFD1_k127_7416026_64 Tetratricopeptide repeat domain protein - - - 0.000006667 58.0
HFD1_k127_7416026_65 cytochrome C - - - 0.000007682 55.0
HFD1_k127_7416026_66 - - - - 0.0004394 53.0
HFD1_k127_7416026_7 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 588.0
HFD1_k127_7416026_8 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 570.0
HFD1_k127_7416026_9 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 559.0
HFD1_k127_7455392_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1201.0
HFD1_k127_7455392_1 FAD linked oxidases, C-terminal domain K06911 - - 0.0 1197.0
HFD1_k127_7455392_10 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 410.0
HFD1_k127_7455392_11 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 403.0
HFD1_k127_7455392_12 domain, Protein K01212,K12287,K20276 - 3.2.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 402.0
HFD1_k127_7455392_13 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 371.0
HFD1_k127_7455392_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 367.0
HFD1_k127_7455392_15 YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 375.0
HFD1_k127_7455392_16 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 377.0
HFD1_k127_7455392_17 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 338.0
HFD1_k127_7455392_18 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 360.0
HFD1_k127_7455392_19 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 340.0
HFD1_k127_7455392_2 PFAM 4Fe-4S K00184,K21308 - - 0.0 1080.0
HFD1_k127_7455392_20 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 323.0
HFD1_k127_7455392_21 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 321.0
HFD1_k127_7455392_22 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 317.0
HFD1_k127_7455392_23 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 299.0
HFD1_k127_7455392_24 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 308.0
HFD1_k127_7455392_25 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 298.0
HFD1_k127_7455392_26 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 294.0
HFD1_k127_7455392_27 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004574 278.0
HFD1_k127_7455392_28 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002905 287.0
HFD1_k127_7455392_29 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002801 277.0
HFD1_k127_7455392_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.119e-280 881.0
HFD1_k127_7455392_30 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001518 275.0
HFD1_k127_7455392_31 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 273.0
HFD1_k127_7455392_32 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001304 276.0
HFD1_k127_7455392_33 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000004082 271.0
HFD1_k127_7455392_34 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002246 248.0
HFD1_k127_7455392_35 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000001041 243.0
HFD1_k127_7455392_36 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000002223 239.0
HFD1_k127_7455392_37 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002055 250.0
HFD1_k127_7455392_38 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000003424 246.0
HFD1_k127_7455392_39 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000006383 229.0
HFD1_k127_7455392_4 Polysulphide reductase, NrfD K00185 - - 7.795e-215 691.0
HFD1_k127_7455392_40 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000009437 216.0
HFD1_k127_7455392_41 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000009503 235.0
HFD1_k127_7455392_42 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000001493 233.0
HFD1_k127_7455392_43 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000002648 212.0
HFD1_k127_7455392_44 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000003555 216.0
HFD1_k127_7455392_45 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000648 219.0
HFD1_k127_7455392_46 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000008473 205.0
HFD1_k127_7455392_47 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000001833 211.0
HFD1_k127_7455392_48 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000003298 213.0
HFD1_k127_7455392_49 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.000000000000000000000000000000000000000000000000000001795 200.0
HFD1_k127_7455392_5 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 606.0
HFD1_k127_7455392_50 methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000005266 186.0
HFD1_k127_7455392_51 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000296 173.0
HFD1_k127_7455392_52 - - - - 0.0000000000000000000000000000000000000000000004054 173.0
HFD1_k127_7455392_53 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000005356 171.0
HFD1_k127_7455392_54 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000002301 160.0
HFD1_k127_7455392_55 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000002849 161.0
HFD1_k127_7455392_56 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000003586 158.0
HFD1_k127_7455392_57 - - - - 0.000000000000000000000000000000000000002682 155.0
HFD1_k127_7455392_58 DoxX K15977 - - 0.00000000000000000000000000000000000006462 148.0
HFD1_k127_7455392_59 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000007698 141.0
HFD1_k127_7455392_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 556.0
HFD1_k127_7455392_60 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000002922 139.0
HFD1_k127_7455392_61 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000752 140.0
HFD1_k127_7455392_62 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000002862 128.0
HFD1_k127_7455392_63 - - - - 0.000000000000000000000000000003352 128.0
HFD1_k127_7455392_64 SMART Metal-dependent phosphohydrolase, HD region K07141 - 2.7.7.76 0.000000000000000000000000000007377 132.0
HFD1_k127_7455392_65 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000107 136.0
HFD1_k127_7455392_66 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000004613 129.0
HFD1_k127_7455392_67 - - - - 0.000000000000000000000000000109 120.0
HFD1_k127_7455392_68 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000004014 119.0
HFD1_k127_7455392_69 - - - - 0.000000000000000000000000005103 122.0
HFD1_k127_7455392_7 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 438.0
HFD1_k127_7455392_70 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000049 110.0
HFD1_k127_7455392_71 Sodium:solute symporter family K03307 - - 0.0000000000000000000000001882 121.0
HFD1_k127_7455392_72 - - - - 0.0000000000000000000000009219 115.0
HFD1_k127_7455392_73 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000003225 100.0
HFD1_k127_7455392_74 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000001933 98.0
HFD1_k127_7455392_75 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.00000000000000000002421 93.0
HFD1_k127_7455392_76 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000001879 100.0
HFD1_k127_7455392_77 Protein kinase domain - - - 0.000000000000000003089 96.0
HFD1_k127_7455392_78 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.000000000000000003852 86.0
HFD1_k127_7455392_79 Transcriptional regulator - - - 0.0000000000000001782 86.0
HFD1_k127_7455392_8 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 441.0
HFD1_k127_7455392_80 - - - - 0.000000000000002125 83.0
HFD1_k127_7455392_81 YXWGXW repeat (2 copies) - - - 0.0000000000001669 81.0
HFD1_k127_7455392_82 gluconolactonase activity - - - 0.0000000000008405 80.0
HFD1_k127_7455392_83 ECF sigma factor - - - 0.0000000003429 65.0
HFD1_k127_7455392_85 - - - - 0.0000004761 55.0
HFD1_k127_7455392_86 Domain of unknown function (DUF4440) - - - 0.0000005238 58.0
HFD1_k127_7455392_87 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000001689 53.0
HFD1_k127_7455392_88 Domain of unknown function (DUF4149) - - - 0.000001882 59.0
HFD1_k127_7455392_89 Putative zinc-finger - - - 0.000003416 57.0
HFD1_k127_7455392_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 421.0
HFD1_k127_7455392_91 MacB-like periplasmic core domain - - - 0.0001477 46.0
HFD1_k127_7455392_92 - - - - 0.0003267 46.0
HFD1_k127_7459150_0 Cytochrome c - - - 2.167e-207 653.0
HFD1_k127_7459150_1 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 368.0
HFD1_k127_7459150_2 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003346 286.0
HFD1_k127_7459150_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000007923 219.0
HFD1_k127_7459150_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000005375 202.0
HFD1_k127_7459150_5 PFAM DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000004392 164.0
HFD1_k127_7459150_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000002564 128.0
HFD1_k127_7459150_7 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000006148 63.0
HFD1_k127_7472155_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 8.17e-243 781.0
HFD1_k127_7472155_1 cellulose binding - - - 1.262e-212 669.0
HFD1_k127_7472155_11 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000009076 132.0
HFD1_k127_7472155_12 Pfam Activator of Hsp90 ATPase - - - 0.0000000000000000000000000196 114.0
HFD1_k127_7472155_13 Adenylate cyclase - - - 0.00000000000000005092 90.0
HFD1_k127_7472155_14 Pfam SNARE associated Golgi protein - - - 0.00000000004596 72.0
HFD1_k127_7472155_15 - - - - 0.00000000006662 71.0
HFD1_k127_7472155_16 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000009285 64.0
HFD1_k127_7472155_17 Tetratricopeptide repeat - - - 0.00000000011 68.0
HFD1_k127_7472155_18 diguanylate cyclase - - - 0.0000000006516 68.0
HFD1_k127_7472155_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.47e-205 649.0
HFD1_k127_7472155_3 Peptidase S46 - - - 4.245e-205 661.0
HFD1_k127_7472155_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 634.0
HFD1_k127_7472155_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 475.0
HFD1_k127_7472155_6 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 460.0
HFD1_k127_7472155_7 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 387.0
HFD1_k127_7472155_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 346.0
HFD1_k127_7472155_9 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000000000000000000431 190.0
HFD1_k127_7474313_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1371.0
HFD1_k127_7474313_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.31e-276 872.0
HFD1_k127_7474313_10 Bacterial sugar transferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 441.0
HFD1_k127_7474313_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 385.0
HFD1_k127_7474313_12 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 382.0
HFD1_k127_7474313_13 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 338.0
HFD1_k127_7474313_14 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 361.0
HFD1_k127_7474313_15 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 331.0
HFD1_k127_7474313_16 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 331.0
HFD1_k127_7474313_17 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 314.0
HFD1_k127_7474313_18 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 293.0
HFD1_k127_7474313_19 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 290.0
HFD1_k127_7474313_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 3.091e-268 835.0
HFD1_k127_7474313_20 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 290.0
HFD1_k127_7474313_21 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 295.0
HFD1_k127_7474313_22 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003929 282.0
HFD1_k127_7474313_23 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003602 278.0
HFD1_k127_7474313_24 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005631 269.0
HFD1_k127_7474313_25 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007948 266.0
HFD1_k127_7474313_26 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000003001 261.0
HFD1_k127_7474313_27 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000116 277.0
HFD1_k127_7474313_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000003638 246.0
HFD1_k127_7474313_29 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000007278 225.0
HFD1_k127_7474313_3 efflux transmembrane transporter activity - - - 2.081e-262 832.0
HFD1_k127_7474313_30 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000007434 226.0
HFD1_k127_7474313_31 cytochrome c nitrite reductase K15876 - - 0.00000000000000000000000000000000000000000000000000000000000007873 216.0
HFD1_k127_7474313_32 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000001195 227.0
HFD1_k127_7474313_33 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000003244 216.0
HFD1_k127_7474313_34 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000000004229 215.0
HFD1_k127_7474313_35 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000008763 213.0
HFD1_k127_7474313_36 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000003901 200.0
HFD1_k127_7474313_37 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000009962 198.0
HFD1_k127_7474313_38 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000003735 201.0
HFD1_k127_7474313_39 - - - - 0.00000000000000000000000000000000000000000000000001083 192.0
HFD1_k127_7474313_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.544e-228 732.0
HFD1_k127_7474313_40 Transmembrane and - - - 0.00000000000000000000000000000000000000000000002004 193.0
HFD1_k127_7474313_41 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000005771 177.0
HFD1_k127_7474313_42 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000614 160.0
HFD1_k127_7474313_43 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000002563 154.0
HFD1_k127_7474313_44 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000002389 137.0
HFD1_k127_7474313_45 PFAM response regulator receiver - - - 0.000000000000000000000000000004285 131.0
HFD1_k127_7474313_46 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000003717 130.0
HFD1_k127_7474313_47 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000005335 125.0
HFD1_k127_7474313_48 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000001886 119.0
HFD1_k127_7474313_49 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000005539 114.0
HFD1_k127_7474313_5 Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 643.0
HFD1_k127_7474313_50 Protein of unknown function DUF58 - - - 0.000000000000000000000000002673 124.0
HFD1_k127_7474313_52 Transglutaminase/protease-like homologues - - - 0.000000000000000000000001032 121.0
HFD1_k127_7474313_53 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000006756 106.0
HFD1_k127_7474313_54 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000007357 106.0
HFD1_k127_7474313_55 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000001058 98.0
HFD1_k127_7474313_56 PFAM conserved K07027 - - 0.000000000000000000003987 106.0
HFD1_k127_7474313_57 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000007435 100.0
HFD1_k127_7474313_58 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.00000000000000000005566 104.0
HFD1_k127_7474313_59 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000007895 95.0
HFD1_k127_7474313_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 562.0
HFD1_k127_7474313_60 Sulfurtransferase TusA K04085 - - 0.000000000000000008798 87.0
HFD1_k127_7474313_61 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000124 90.0
HFD1_k127_7474313_62 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000001344 97.0
HFD1_k127_7474313_63 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000000000003243 87.0
HFD1_k127_7474313_64 Protein of unknown function, DUF481 K07283 - - 0.0000000000006378 79.0
HFD1_k127_7474313_65 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000001104 77.0
HFD1_k127_7474313_66 SNARE associated Golgi protein - - - 0.0000000001759 63.0
HFD1_k127_7474313_69 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain K05989 - 3.2.1.40 0.000741 49.0
HFD1_k127_7474313_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 514.0
HFD1_k127_7474313_70 Tetratricopeptide repeat - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006457,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655 - 0.0008665 48.0
HFD1_k127_7474313_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 479.0
HFD1_k127_7474313_9 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 479.0
HFD1_k127_7530806_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 487.0
HFD1_k127_7530806_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 437.0
HFD1_k127_7530806_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 301.0
HFD1_k127_7530806_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 292.0
HFD1_k127_7535225_0 Protein export membrane protein K03296,K18138 - - 0.0 1245.0
HFD1_k127_7535225_1 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 466.0
HFD1_k127_7535225_10 membrane - - - 0.00000000000000000000000000000000000000000000000000000006247 205.0
HFD1_k127_7535225_13 - - - - 0.0000000000000000000000000000000000000000001858 175.0
HFD1_k127_7535225_14 Ion transport 2 domain protein - - - 0.000000000000000000000000000000000000000006658 163.0
HFD1_k127_7535225_15 YMGG-like Gly-zipper - - - 0.00000000000000000000000000000007318 132.0
HFD1_k127_7535225_17 - - - - 0.000000000000000000003927 100.0
HFD1_k127_7535225_18 Domain of unknown function (DUF4136) - - - 0.0000000004956 70.0
HFD1_k127_7535225_2 surface antigen variable number repeat protein K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 469.0
HFD1_k127_7535225_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 432.0
HFD1_k127_7535225_4 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 391.0
HFD1_k127_7535225_5 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 375.0
HFD1_k127_7535225_6 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
HFD1_k127_7535225_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003589 260.0
HFD1_k127_7535225_8 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000001745 231.0
HFD1_k127_7535225_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000008603 209.0
HFD1_k127_7537963_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.438e-314 1000.0
HFD1_k127_7537963_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.028e-286 903.0
HFD1_k127_7537963_10 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 516.0
HFD1_k127_7537963_100 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000007699 155.0
HFD1_k127_7537963_101 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000001469 154.0
HFD1_k127_7537963_102 Bacterial Ig-like domain (group 3) K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000000000000000003771 159.0
HFD1_k127_7537963_103 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000006772 151.0
HFD1_k127_7537963_104 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000002847 154.0
HFD1_k127_7537963_105 histone H2A K63-linked ubiquitination K10914 - - 0.0000000000000000000000000000000004361 149.0
HFD1_k127_7537963_106 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000004624 148.0
HFD1_k127_7537963_107 Tetratricopeptide repeat - - - 0.00000000000000000000000000000001384 146.0
HFD1_k127_7537963_108 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000000000003459 136.0
HFD1_k127_7537963_109 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000004457 132.0
HFD1_k127_7537963_11 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 524.0
HFD1_k127_7537963_110 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001338 140.0
HFD1_k127_7537963_111 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000001413 125.0
HFD1_k127_7537963_112 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000002849 130.0
HFD1_k127_7537963_113 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000008398 136.0
HFD1_k127_7537963_114 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000009296 128.0
HFD1_k127_7537963_115 Transglycosylase SLT domain - - - 0.000000000000000000000000000001651 137.0
HFD1_k127_7537963_116 Could be involved in septation K06412 - - 0.000000000000000000000000000002417 125.0
HFD1_k127_7537963_117 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000001088 129.0
HFD1_k127_7537963_118 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000006376 115.0
HFD1_k127_7537963_119 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000000000115 117.0
HFD1_k127_7537963_12 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 484.0
HFD1_k127_7537963_120 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000165 117.0
HFD1_k127_7537963_121 phosphorelay signal transduction system - - - 0.00000000000000000000000003997 124.0
HFD1_k127_7537963_122 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000004342 115.0
HFD1_k127_7537963_123 Belongs to the GcvT family K06980 - - 0.00000000000000000000000006007 119.0
HFD1_k127_7537963_124 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000006841 110.0
HFD1_k127_7537963_125 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000208 111.0
HFD1_k127_7537963_126 YXWGXW repeat (2 copies) - - - 0.000000000000000000000002282 105.0
HFD1_k127_7537963_127 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000001218 113.0
HFD1_k127_7537963_128 Phosphotransferase System K11189 - - 0.000000000000000000001091 102.0
HFD1_k127_7537963_129 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000000000002836 98.0
HFD1_k127_7537963_13 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 488.0
HFD1_k127_7537963_130 thiolester hydrolase activity K17362 - - 0.00000000000000000003745 98.0
HFD1_k127_7537963_131 CHRD domain - - - 0.00000000000000000005723 103.0
HFD1_k127_7537963_132 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000004899 93.0
HFD1_k127_7537963_133 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000006827 94.0
HFD1_k127_7537963_134 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000001568 97.0
HFD1_k127_7537963_135 tetratricopeptide repeat - - - 0.00000000000000001637 98.0
HFD1_k127_7537963_136 TonB C terminal K03646,K03832 - - 0.00000000000000006198 90.0
HFD1_k127_7537963_137 COG1214 Inactive homolog of metal-dependent proteases K01409,K14742 - 2.3.1.234 0.0000000000000001574 87.0
HFD1_k127_7537963_138 - - - - 0.000000000000002098 90.0
HFD1_k127_7537963_14 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 484.0
HFD1_k127_7537963_140 lipopolysaccharide transport K09774 - - 0.0000000000001214 85.0
HFD1_k127_7537963_141 - - - - 0.000000000005745 76.0
HFD1_k127_7537963_142 type II secretion system protein E K02652 - - 0.00000000002536 76.0
HFD1_k127_7537963_144 Predicted membrane protein (DUF2232) - - - 0.0000000004787 71.0
HFD1_k127_7537963_145 Binds directly to 16S ribosomal RNA K02968 - - 0.00000002929 58.0
HFD1_k127_7537963_146 Transglutaminase-like superfamily - - - 0.00000003757 65.0
HFD1_k127_7537963_147 Domain of unknown function (DUF4126) - - - 0.0000001116 64.0
HFD1_k127_7537963_148 type II secretion system protein E K02652 - - 0.0000002094 63.0
HFD1_k127_7537963_149 polyketide synthase - - - 0.0000004791 62.0
HFD1_k127_7537963_15 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 486.0
HFD1_k127_7537963_150 heat shock protein binding - - - 0.000004313 60.0
HFD1_k127_7537963_151 protein conserved in bacteria K03749 - - 0.0001551 51.0
HFD1_k127_7537963_152 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.0001956 54.0
HFD1_k127_7537963_153 deoxyhypusine monooxygenase activity - - - 0.0005405 52.0
HFD1_k127_7537963_16 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 468.0
HFD1_k127_7537963_17 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 455.0
HFD1_k127_7537963_18 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 443.0
HFD1_k127_7537963_19 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 439.0
HFD1_k127_7537963_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.488e-265 844.0
HFD1_k127_7537963_20 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 433.0
HFD1_k127_7537963_21 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 433.0
HFD1_k127_7537963_22 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 418.0
HFD1_k127_7537963_23 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 414.0
HFD1_k127_7537963_24 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 404.0
HFD1_k127_7537963_25 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 413.0
HFD1_k127_7537963_26 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 403.0
HFD1_k127_7537963_27 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 382.0
HFD1_k127_7537963_28 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 383.0
HFD1_k127_7537963_29 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 374.0
HFD1_k127_7537963_3 Urocanase C-terminal domain K01712 - 4.2.1.49 5.943e-252 788.0
HFD1_k127_7537963_30 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 375.0
HFD1_k127_7537963_31 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 377.0
HFD1_k127_7537963_32 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 360.0
HFD1_k127_7537963_33 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 366.0
HFD1_k127_7537963_34 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 346.0
HFD1_k127_7537963_35 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 354.0
HFD1_k127_7537963_36 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 342.0
HFD1_k127_7537963_37 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 340.0
HFD1_k127_7537963_38 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 336.0
HFD1_k127_7537963_39 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 326.0
HFD1_k127_7537963_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.037e-199 651.0
HFD1_k127_7537963_40 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 329.0
HFD1_k127_7537963_41 Peptidase M36 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 336.0
HFD1_k127_7537963_42 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 333.0
HFD1_k127_7537963_43 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 320.0
HFD1_k127_7537963_44 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 340.0
HFD1_k127_7537963_45 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 318.0
HFD1_k127_7537963_46 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 339.0
HFD1_k127_7537963_47 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 308.0
HFD1_k127_7537963_48 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 308.0
HFD1_k127_7537963_49 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 321.0
HFD1_k127_7537963_5 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 617.0
HFD1_k127_7537963_50 PFAM ABC transporter related K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 297.0
HFD1_k127_7537963_51 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 315.0
HFD1_k127_7537963_52 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 302.0
HFD1_k127_7537963_53 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 291.0
HFD1_k127_7537963_54 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 290.0
HFD1_k127_7537963_55 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000133 285.0
HFD1_k127_7537963_56 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001113 279.0
HFD1_k127_7537963_57 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003696 282.0
HFD1_k127_7537963_58 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000001237 268.0
HFD1_k127_7537963_59 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001158 267.0
HFD1_k127_7537963_6 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 599.0
HFD1_k127_7537963_60 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001642 265.0
HFD1_k127_7537963_61 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000001256 243.0
HFD1_k127_7537963_62 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000004723 253.0
HFD1_k127_7537963_63 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000000000000008841 245.0
HFD1_k127_7537963_64 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000001039 250.0
HFD1_k127_7537963_65 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000212 231.0
HFD1_k127_7537963_66 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000433 229.0
HFD1_k127_7537963_67 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000008108 238.0
HFD1_k127_7537963_68 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000001642 225.0
HFD1_k127_7537963_69 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000004261 227.0
HFD1_k127_7537963_7 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 570.0
HFD1_k127_7537963_70 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000003687 198.0
HFD1_k127_7537963_71 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000006515 204.0
HFD1_k127_7537963_72 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000006666 203.0
HFD1_k127_7537963_73 peptidase U61 K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000002345 203.0
HFD1_k127_7537963_74 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.00000000000000000000000000000000000000000000000000003539 216.0
HFD1_k127_7537963_75 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000001137 203.0
HFD1_k127_7537963_76 SMART CBS domain containing protein K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000001092 199.0
HFD1_k127_7537963_77 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000001135 203.0
HFD1_k127_7537963_78 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000131 188.0
HFD1_k127_7537963_79 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000005485 191.0
HFD1_k127_7537963_8 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 529.0
HFD1_k127_7537963_80 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000003243 190.0
HFD1_k127_7537963_81 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000005835 173.0
HFD1_k127_7537963_82 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000007658 173.0
HFD1_k127_7537963_83 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000002285 185.0
HFD1_k127_7537963_84 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000002949 192.0
HFD1_k127_7537963_85 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000004603 178.0
HFD1_k127_7537963_86 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000005492 171.0
HFD1_k127_7537963_87 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000002621 168.0
HFD1_k127_7537963_88 TIGR00255 family - - - 0.0000000000000000000000000000000000000000001196 183.0
HFD1_k127_7537963_89 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000002515 167.0
HFD1_k127_7537963_9 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 543.0
HFD1_k127_7537963_90 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000003389 181.0
HFD1_k127_7537963_91 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000005155 166.0
HFD1_k127_7537963_92 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000005369 161.0
HFD1_k127_7537963_93 - K07018 - - 0.0000000000000000000000000000000000000000008846 167.0
HFD1_k127_7537963_94 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000002669 165.0
HFD1_k127_7537963_95 PAP2 superfamily - - - 0.00000000000000000000000000000000000000002394 165.0
HFD1_k127_7537963_96 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000001175 157.0
HFD1_k127_7537963_97 NmrA-like family - - - 0.000000000000000000000000000000000000000209 164.0
HFD1_k127_7537963_98 NUDIX domain - - - 0.000000000000000000000000000000000000002507 153.0
HFD1_k127_7537963_99 OmpA family K03640 - - 0.000000000000000000000000000000000000004016 153.0
HFD1_k127_7572637_0 Carbamoyltransferase C-terminus K00612 - - 7e-323 996.0
HFD1_k127_7572637_1 ACT domain K12524 - 1.1.1.3,2.7.2.4 2.379e-260 832.0
HFD1_k127_7572637_10 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 360.0
HFD1_k127_7572637_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 355.0
HFD1_k127_7572637_12 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 351.0
HFD1_k127_7572637_13 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 287.0
HFD1_k127_7572637_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006195 288.0
HFD1_k127_7572637_15 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006254 298.0
HFD1_k127_7572637_16 Glycosyltransferase group 2 family protein K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
HFD1_k127_7572637_17 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003459 264.0
HFD1_k127_7572637_18 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000409 265.0
HFD1_k127_7572637_19 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004684 263.0
HFD1_k127_7572637_2 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.468e-217 687.0
HFD1_k127_7572637_20 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000001762 242.0
HFD1_k127_7572637_21 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000004483 228.0
HFD1_k127_7572637_22 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000002036 225.0
HFD1_k127_7572637_23 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000001781 209.0
HFD1_k127_7572637_24 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000231 201.0
HFD1_k127_7572637_25 GHMP kinases C terminal K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0050896,GO:0051704,GO:0051707,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000002126 202.0
HFD1_k127_7572637_26 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000205 183.0
HFD1_k127_7572637_27 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000003297 188.0
HFD1_k127_7572637_28 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000001145 173.0
HFD1_k127_7572637_29 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000001212 169.0
HFD1_k127_7572637_3 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 522.0
HFD1_k127_7572637_30 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000001071 151.0
HFD1_k127_7572637_31 membrane - - - 0.0000000000000000000000000000000000001659 156.0
HFD1_k127_7572637_33 RES - - - 0.000000000000000000000000000000000000194 160.0
HFD1_k127_7572637_34 positive regulation of growth K19687 - - 0.000000000000000000002044 98.0
HFD1_k127_7572637_35 integral membrane protein - - - 0.00000000000000000002028 106.0
HFD1_k127_7572637_36 - - - - 0.00000000000000000002472 105.0
HFD1_k127_7572637_37 Protein of unknown function (DUF2384) - - - 0.0000000000000000004303 92.0
HFD1_k127_7572637_38 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000007049 100.0
HFD1_k127_7572637_39 Periplasmic or secreted lipoprotein K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.000000000000000000705 95.0
HFD1_k127_7572637_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 527.0
HFD1_k127_7572637_40 beta-galactosidase activity - - - 0.000000000000000001211 93.0
HFD1_k127_7572637_41 - - - - 0.00000000000001408 74.0
HFD1_k127_7572637_42 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000009098 82.0
HFD1_k127_7572637_43 transferase activity, transferring glycosyl groups K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000002282 79.0
HFD1_k127_7572637_44 Periplasmic or secreted lipoprotein K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.00000000001221 78.0
HFD1_k127_7572637_45 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000004906 69.0
HFD1_k127_7572637_46 lipolytic protein G-D-S-L family - - - 0.000000001907 70.0
HFD1_k127_7572637_47 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0007154,GO:0007165,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0015688,GO:0015833,GO:0015889,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019062,GO:0019904,GO:0022610,GO:0023052,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0031992,GO:0032991,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0042914,GO:0043213,GO:0044403,GO:0044406,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0044650,GO:0046813,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0051704,GO:0051716,GO:0060089,GO:0065007,GO:0071575,GO:0071702,GO:0071705,GO:0071944,GO:0098002,GO:0098552,GO:0098670,GO:0098796,GO:0098797,GO:1901678 - 0.000000002609 68.0
HFD1_k127_7572637_48 guanyl-nucleotide exchange factor activity K20276 - - 0.00000002337 61.0
HFD1_k127_7572637_49 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.000002746 61.0
HFD1_k127_7572637_5 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 515.0
HFD1_k127_7572637_50 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001071 56.0
HFD1_k127_7572637_51 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001212 55.0
HFD1_k127_7572637_52 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.0001219 55.0
HFD1_k127_7572637_6 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 476.0
HFD1_k127_7572637_8 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 418.0
HFD1_k127_7572637_9 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 377.0
HFD1_k127_7579718_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 606.0
HFD1_k127_7579718_1 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 544.0
HFD1_k127_7579718_10 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000000001063 156.0
HFD1_k127_7579718_11 Cytochrome c - - - 0.00000000000000000000000000000000000005126 150.0
HFD1_k127_7579718_12 BetI-type transcriptional repressor, C-terminal - - - 0.0000000000000000000000000000000000002014 148.0
HFD1_k127_7579718_13 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000007399 132.0
HFD1_k127_7579718_14 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000007639 127.0
HFD1_k127_7579718_15 SnoaL-like domain - - - 0.00000000000000000000000000005132 127.0
HFD1_k127_7579718_16 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.00000000000000000000000000729 121.0
HFD1_k127_7579718_17 methyltransferase activity - - - 0.000000000000000000000000239 111.0
HFD1_k127_7579718_18 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000001088 98.0
HFD1_k127_7579718_19 Biopolymer transport protein K03560 - - 0.00000000000004285 79.0
HFD1_k127_7579718_2 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 402.0
HFD1_k127_7579718_20 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.0000000000003462 72.0
HFD1_k127_7579718_21 - - - - 0.00001443 53.0
HFD1_k127_7579718_22 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.00008702 45.0
HFD1_k127_7579718_23 Putative zinc- or iron-chelating domain - - - 0.0003084 50.0
HFD1_k127_7579718_3 Acts as a magnesium transporter K04767,K06213,K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 396.0
HFD1_k127_7579718_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 368.0
HFD1_k127_7579718_5 short-chain dehydrogenase K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007576 277.0
HFD1_k127_7579718_6 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002948 264.0
HFD1_k127_7579718_7 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000512 250.0
HFD1_k127_7579718_8 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000001811 203.0
HFD1_k127_7579718_9 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000002497 180.0
HFD1_k127_7600164_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1441.0
HFD1_k127_7600164_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 5.665e-242 756.0
HFD1_k127_7600164_2 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 567.0
HFD1_k127_7600164_3 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 505.0
HFD1_k127_7600164_4 sensor diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 472.0
HFD1_k127_7600164_5 RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 458.0
HFD1_k127_7600164_6 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 362.0
HFD1_k127_7600164_7 serine-type endopeptidase activity K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000002022 235.0
HFD1_k127_7644953_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 3.966e-242 762.0
HFD1_k127_7644953_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00244,K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 592.0
HFD1_k127_7644953_10 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001477 269.0
HFD1_k127_7644953_11 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000001999 181.0
HFD1_k127_7644953_12 Response regulator receiver - - - 0.000000000000000000000000000000001036 138.0
HFD1_k127_7644953_13 Mannosyltransferase (PIG-V) - - - 0.000000000000000000000000000004236 136.0
HFD1_k127_7644953_14 - - - - 0.000003527 58.0
HFD1_k127_7644953_15 Histidine kinase - - - 0.0001093 52.0
HFD1_k127_7644953_2 peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 531.0
HFD1_k127_7644953_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 442.0
HFD1_k127_7644953_4 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 405.0
HFD1_k127_7644953_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 400.0
HFD1_k127_7644953_6 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 360.0
HFD1_k127_7644953_7 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 357.0
HFD1_k127_7644953_8 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 344.0
HFD1_k127_7644953_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001112 279.0
HFD1_k127_7675402_0 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 410.0
HFD1_k127_7675402_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 358.0
HFD1_k127_7675402_2 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000151 217.0
HFD1_k127_7675402_3 Hsp70 protein - - - 0.00000000000000000000000000000000000000000000000000004911 199.0
HFD1_k127_7675402_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001125 177.0
HFD1_k127_7730262_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1457.0
HFD1_k127_7730262_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1293.0
HFD1_k127_7730262_10 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 383.0
HFD1_k127_7730262_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 371.0
HFD1_k127_7730262_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 382.0
HFD1_k127_7730262_13 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 342.0
HFD1_k127_7730262_14 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 342.0
HFD1_k127_7730262_15 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 292.0
HFD1_k127_7730262_16 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001112 303.0
HFD1_k127_7730262_17 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003963 287.0
HFD1_k127_7730262_18 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003223 298.0
HFD1_k127_7730262_19 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006893 279.0
HFD1_k127_7730262_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 5.429e-207 684.0
HFD1_k127_7730262_20 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001218 273.0
HFD1_k127_7730262_21 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002498 268.0
HFD1_k127_7730262_22 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000115 253.0
HFD1_k127_7730262_23 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001566 263.0
HFD1_k127_7730262_24 cation efflux K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000001042 232.0
HFD1_k127_7730262_25 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000001136 222.0
HFD1_k127_7730262_26 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000007883 179.0
HFD1_k127_7730262_27 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000005063 169.0
HFD1_k127_7730262_28 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000306 151.0
HFD1_k127_7730262_29 Cytochrome c - - - 0.00000000000000000000000000000000001593 143.0
HFD1_k127_7730262_3 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 537.0
HFD1_k127_7730262_30 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000005966 132.0
HFD1_k127_7730262_31 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000002822 134.0
HFD1_k127_7730262_32 Chromate resistance exported protein - - - 0.0000000000000000000000000002769 119.0
HFD1_k127_7730262_33 SMART phosphoesterase PA-phosphatase related - - - 0.00000000000000000000000001688 120.0
HFD1_k127_7730262_34 Belongs to the 'phage' integrase family - - - 0.000000000000000000000002313 112.0
HFD1_k127_7730262_35 Cytochrome C assembly protein - - - 0.00000000000000000000000704 111.0
HFD1_k127_7730262_36 DNA integration - - - 0.000000001414 66.0
HFD1_k127_7730262_37 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000003427 70.0
HFD1_k127_7730262_38 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000001102 61.0
HFD1_k127_7730262_39 amine dehydrogenase activity - - - 0.00001017 57.0
HFD1_k127_7730262_4 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 471.0
HFD1_k127_7730262_40 Outer membrane efflux protein - - - 0.0001474 54.0
HFD1_k127_7730262_41 Chromate transporter K07240 - - 0.0002762 46.0
HFD1_k127_7730262_5 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 446.0
HFD1_k127_7730262_6 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 444.0
HFD1_k127_7730262_7 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 453.0
HFD1_k127_7730262_8 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 452.0
HFD1_k127_7730262_9 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 447.0
HFD1_k127_7882422_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 342.0
HFD1_k127_7882422_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000001462 228.0
HFD1_k127_839447_0 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 597.0
HFD1_k127_839447_1 Outer membrane receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 582.0
HFD1_k127_839447_2 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 437.0
HFD1_k127_839447_3 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 351.0
HFD1_k127_839447_4 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 323.0
HFD1_k127_847067_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1045.0
HFD1_k127_847067_1 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 376.0
HFD1_k127_847067_2 2Fe-2S -binding K13483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001907 250.0
HFD1_k127_847067_3 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002468 251.0
HFD1_k127_847067_4 - - - - 0.000000000000000000000000000456 126.0
HFD1_k127_847067_5 Transcriptional regulator - - - 0.00000000000000000003178 93.0
HFD1_k127_847067_6 - - - - 0.00007865 48.0
HFD1_k127_917289_0 Involved in the tonB-independent uptake of proteins - - - 1.766e-206 671.0
HFD1_k127_917289_1 Involved in the tonB-independent uptake of proteins - - - 5.342e-198 646.0
HFD1_k127_917289_2 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 532.0
HFD1_k127_917289_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 321.0
HFD1_k127_917289_4 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006169 251.0
HFD1_k127_917289_5 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000004565 225.0
HFD1_k127_917289_6 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.0000000000000000000000000000000000000000000000000004306 191.0
HFD1_k127_917289_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000007081 185.0
HFD1_k127_917289_8 thyroxine 5'-deiodinase activity K01562 GO:0003674,GO:0003824,GO:0004800,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008430,GO:0009987,GO:0010817,GO:0016020,GO:0016491,GO:0018958,GO:0042403,GO:0042445,GO:0044237,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901360,GO:1901564,GO:1901615 1.21.99.4 0.0000000000000000000000000005669 117.0
HFD1_k127_917289_9 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000001249 59.0
HFD1_k127_923963_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 6.476e-275 869.0
HFD1_k127_923963_1 Involved in the tonB-independent uptake of proteins - - - 6.955e-194 632.0
HFD1_k127_923963_2 regulation of translation K03530 - - 0.000000000000000000000000000000000007988 139.0
HFD1_k127_923963_3 FR47-like protein - - - 0.000000000000000000000003087 109.0
HFD1_k127_923963_4 Thioesterase superfamily - - - 0.00000000000000000000002182 108.0
HFD1_k127_929970_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000007439 215.0
HFD1_k127_929970_1 metallopeptidase activity K01993,K13408,K16922 - - 0.000000000000000000000000000000000000000000000000000000000008442 233.0
HFD1_k127_929970_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.0000000000000000000000000000000000000000001256 183.0
HFD1_k127_929970_3 STAS domain K04749 - - 0.00000000000004291 76.0
HFD1_k127_932290_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 372.0
HFD1_k127_932290_1 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001529 308.0
HFD1_k127_932290_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001414 261.0
HFD1_k127_932290_3 dihydrofolate reductase activity K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
HFD1_k127_932290_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000002918 206.0
HFD1_k127_932290_5 - - - - 0.00000000000000000000000001486 114.0
HFD1_k127_932290_6 PFAM 3-demethylubiquinone-9 K04750 - - 0.000000000000000000000000473 105.0
HFD1_k127_932290_7 - - - - 0.0002688 47.0
HFD1_k127_957257_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 480.0
HFD1_k127_957257_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 424.0
HFD1_k127_957257_2 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 342.0
HFD1_k127_957257_3 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
HFD1_k127_957257_4 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000001711 139.0
HFD1_k127_99955_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1048.0
HFD1_k127_99955_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 6.927e-296 923.0
HFD1_k127_99955_10 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 430.0
HFD1_k127_99955_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 425.0
HFD1_k127_99955_12 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 402.0
HFD1_k127_99955_13 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 373.0
HFD1_k127_99955_14 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 357.0
HFD1_k127_99955_15 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 356.0
HFD1_k127_99955_16 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 349.0
HFD1_k127_99955_17 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 349.0
HFD1_k127_99955_18 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 358.0
HFD1_k127_99955_19 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 357.0
HFD1_k127_99955_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.557e-249 797.0
HFD1_k127_99955_20 alpha beta alpha domain I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 341.0
HFD1_k127_99955_21 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 316.0
HFD1_k127_99955_22 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 326.0
HFD1_k127_99955_23 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 316.0
HFD1_k127_99955_24 Oligopeptide/dipeptide transporter, C-terminal region K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 304.0
HFD1_k127_99955_25 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 301.0
HFD1_k127_99955_26 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 306.0
HFD1_k127_99955_27 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 270.0
HFD1_k127_99955_28 CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001767 269.0
HFD1_k127_99955_29 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003936 265.0
HFD1_k127_99955_3 Heat shock 70 kDa protein K04043 - - 1.529e-232 739.0
HFD1_k127_99955_30 ThiF family K03148,K21029 - 2.7.7.73,2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000001504 260.0
HFD1_k127_99955_31 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002404 252.0
HFD1_k127_99955_32 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000001149 246.0
HFD1_k127_99955_33 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000001522 237.0
HFD1_k127_99955_34 maltose O-acetyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003457 245.0
HFD1_k127_99955_35 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000003886 244.0
HFD1_k127_99955_36 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001561 234.0
HFD1_k127_99955_37 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000025 231.0
HFD1_k127_99955_38 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000003376 235.0
HFD1_k127_99955_39 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000002454 226.0
HFD1_k127_99955_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 8.415e-199 633.0
HFD1_k127_99955_40 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 0.000000000000000000000000000000000000000000000000000000008988 220.0
HFD1_k127_99955_41 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000005792 197.0
HFD1_k127_99955_42 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000001037 207.0
HFD1_k127_99955_43 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000009125 169.0
HFD1_k127_99955_44 response regulator - - - 0.0000000000000000000000000000000000000000004175 173.0
HFD1_k127_99955_45 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000001456 167.0
HFD1_k127_99955_46 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000000000000000000000003899 169.0
HFD1_k127_99955_47 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000001211 166.0
HFD1_k127_99955_48 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001524 162.0
HFD1_k127_99955_49 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000001512 147.0
HFD1_k127_99955_5 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 594.0
HFD1_k127_99955_50 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000003015 156.0
HFD1_k127_99955_51 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000005178 143.0
HFD1_k127_99955_52 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.000000000000000000000000000000001576 138.0
HFD1_k127_99955_53 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000004418 151.0
HFD1_k127_99955_54 protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000001205 127.0
HFD1_k127_99955_55 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000001385 124.0
HFD1_k127_99955_56 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000001112 123.0
HFD1_k127_99955_57 Belongs to the ompA family - - - 0.000000000000000000000000001726 126.0
HFD1_k127_99955_58 TIGRFAM TonB K03832 - - 0.00000000000000000000000002379 118.0
HFD1_k127_99955_59 Peptidase family M28 - - - 0.00000000000000000000000006717 123.0
HFD1_k127_99955_6 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 493.0
HFD1_k127_99955_60 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000000001914 112.0
HFD1_k127_99955_61 Tetratricopeptide repeat - - - 0.00000000000000000000000022 119.0
HFD1_k127_99955_62 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000003906 118.0
HFD1_k127_99955_63 oxidoreductase activity - - - 0.00000000000000000000001802 116.0
HFD1_k127_99955_64 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000003117 101.0
HFD1_k127_99955_65 Rossmann-like domain - - - 0.0000000000000000000006203 106.0
HFD1_k127_99955_66 Glutathione peroxidase - - - 0.000000000000000000001102 109.0
HFD1_k127_99955_67 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000001502 99.0
HFD1_k127_99955_68 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000001165 100.0
HFD1_k127_99955_69 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000003941 91.0
HFD1_k127_99955_7 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 473.0
HFD1_k127_99955_70 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002859 78.0
HFD1_k127_99955_71 SMART Tetratricopeptide - - - 0.000000000000004422 83.0
HFD1_k127_99955_72 Mitochondrial biogenesis AIM24 - - - 0.0000000002813 72.0
HFD1_k127_99955_73 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000061 72.0
HFD1_k127_99955_74 Tetratricopeptide repeat - - - 0.000000003263 70.0
HFD1_k127_99955_75 tRNA wobble adenosine to inosine editing - - - 0.000000003769 61.0
HFD1_k127_99955_76 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.00000001377 63.0
HFD1_k127_99955_77 Outer membrane protein beta-barrel domain - - - 0.0000002155 61.0
HFD1_k127_99955_78 COG3764 Sortase (surface protein transpeptidase) K07284 - 3.4.22.70 0.0000002539 60.0
HFD1_k127_99955_79 antisigma factor binding K03598 - - 0.00000715 56.0
HFD1_k127_99955_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 463.0
HFD1_k127_99955_80 monooxygenase activity - - - 0.000224 48.0
HFD1_k127_99955_9 Mg chelatase-like protein K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 463.0