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Overview

ID MAG01611
Name HFD1_bin.18
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order UBA7656
Family UBA7656
Genus JADGNW01
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 0.22
GC content (%) 55.0
N50 (bp) 32,339
Genome size (bp) 7,052,222

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5220

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1001894_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 289.0
HFD1_k127_1001894_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000004436 129.0
HFD1_k127_1005803_0 PFAM Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
HFD1_k127_1005803_1 SprB repeat - - - 0.00000000000000000000000000000000000000000000002641 192.0
HFD1_k127_1010801_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 595.0
HFD1_k127_1010801_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000011 83.0
HFD1_k127_101976_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K15342 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 590.0
HFD1_k127_101976_1 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 289.0
HFD1_k127_101976_2 - - - - 0.00000000008652 64.0
HFD1_k127_101976_3 membrane - - - 0.00014 47.0
HFD1_k127_1023801_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00700 - 2.4.1.18 1.052e-229 730.0
HFD1_k127_1023801_1 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 517.0
HFD1_k127_1023801_10 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000003614 148.0
HFD1_k127_1023801_11 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000001905 147.0
HFD1_k127_1023801_12 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000003487 138.0
HFD1_k127_1023801_13 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000003717 114.0
HFD1_k127_1023801_15 Oxidoreductase - - - 0.0000000000000002059 82.0
HFD1_k127_1023801_16 Transcriptional regulator - - - 0.00000000005471 70.0
HFD1_k127_1023801_17 DNA polymerase Ligase (LigD) - - - 0.00000001568 56.0
HFD1_k127_1023801_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 423.0
HFD1_k127_1023801_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000008145 241.0
HFD1_k127_1023801_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000005144 236.0
HFD1_k127_1023801_5 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000013 231.0
HFD1_k127_1023801_6 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000003204 225.0
HFD1_k127_1023801_7 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000001123 189.0
HFD1_k127_1023801_8 Membrane - - - 0.0000000000000000000000000000000000000000000000001373 186.0
HFD1_k127_1023801_9 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000195 153.0
HFD1_k127_104019_0 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001458 225.0
HFD1_k127_1042955_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.14e-229 719.0
HFD1_k127_1042955_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 520.0
HFD1_k127_1042955_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 385.0
HFD1_k127_1042955_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 352.0
HFD1_k127_1042955_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000421 286.0
HFD1_k127_1042955_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000003435 109.0
HFD1_k127_1042955_6 VanZ like family - - - 0.00000000000000000046 93.0
HFD1_k127_1042955_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000001237 69.0
HFD1_k127_1042955_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000009344 66.0
HFD1_k127_1044569_0 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 569.0
HFD1_k127_1044569_1 methyltransferase - - - 0.000000000000000000000007303 105.0
HFD1_k127_1044913_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 543.0
HFD1_k127_1044913_1 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 519.0
HFD1_k127_1044913_2 COG0644 Dehydrogenases (flavoproteins) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 411.0
HFD1_k127_1044913_3 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 382.0
HFD1_k127_1044913_4 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 358.0
HFD1_k127_1044913_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 327.0
HFD1_k127_1044913_6 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 299.0
HFD1_k127_1044913_7 Protein of unknown function (DUF3311) - - - 0.000000000003181 70.0
HFD1_k127_106459_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 371.0
HFD1_k127_106459_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 296.0
HFD1_k127_106459_2 Helix-hairpin-helix DNA-binding, class 1 K02347 - - 0.00000000000000000000000001206 115.0
HFD1_k127_106459_3 - - - - 0.00000000000000000000000764 107.0
HFD1_k127_106459_4 - - - - 0.000000000000000009997 97.0
HFD1_k127_106459_5 PBS lyase HEAT-like repeat - - - 0.000000000000007284 84.0
HFD1_k127_106459_6 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000006119 60.0
HFD1_k127_1077536_0 4Fe-4S dicluster domain K00184 - - 0.0 1065.0
HFD1_k127_1077536_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 1.421e-218 695.0
HFD1_k127_1077536_2 MFS/sugar transport protein K16211 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 613.0
HFD1_k127_1077536_3 Glycogen debranching enzyme, glucanotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 334.0
HFD1_k127_1077536_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 306.0
HFD1_k127_1077536_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000002801 66.0
HFD1_k127_1077536_6 Phage integrase family - - - 0.0003014 47.0
HFD1_k127_1085563_0 domain protein - - - 4.269e-256 825.0
HFD1_k127_1099145_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001971 276.0
HFD1_k127_1099145_1 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000006077 174.0
HFD1_k127_1104731_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000001132 141.0
HFD1_k127_1104731_1 Winged helix-turn helix - - - 0.000003735 52.0
HFD1_k127_1120932_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.022e-249 781.0
HFD1_k127_1120932_1 Peptidase family M49 - - - 8.971e-200 636.0
HFD1_k127_1120932_10 Tetratricopeptide repeat - - - 0.00008725 56.0
HFD1_k127_1120932_11 Peptidase family M1 domain - - - 0.0007948 53.0
HFD1_k127_1120932_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 454.0
HFD1_k127_1120932_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 382.0
HFD1_k127_1120932_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 346.0
HFD1_k127_1120932_5 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 351.0
HFD1_k127_1120932_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000005071 258.0
HFD1_k127_1120932_7 Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase, chloroplastic-like K00507,K20416 - 1.14.19.1,1.14.19.42 0.0000000000000000000000000000000000000000206 166.0
HFD1_k127_1120932_8 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000002006 117.0
HFD1_k127_1120932_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000001442 111.0
HFD1_k127_1136079_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 560.0
HFD1_k127_1136079_1 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 575.0
HFD1_k127_1136079_10 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000000001579 153.0
HFD1_k127_1136079_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000009831 127.0
HFD1_k127_1136079_12 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000002574 113.0
HFD1_k127_1136079_13 - - - - 0.000000000000000004176 92.0
HFD1_k127_1136079_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000007636 90.0
HFD1_k127_1136079_15 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000001959 78.0
HFD1_k127_1136079_16 Caspase domain - - - 0.0000000000004087 83.0
HFD1_k127_1136079_17 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000001789 70.0
HFD1_k127_1136079_18 Glycosyl transferase, family 2 K20444 - - 0.0004209 53.0
HFD1_k127_1136079_2 NADH dehydrogenase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 422.0
HFD1_k127_1136079_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 393.0
HFD1_k127_1136079_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 347.0
HFD1_k127_1136079_5 - - - - 0.00000000000000000000000000000000000000000000000000000000002824 223.0
HFD1_k127_1136079_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000004394 199.0
HFD1_k127_1136079_7 Protein of unknown function (DUF1175) K09934 - - 0.000000000000000000000000000000000000000000000000001382 193.0
HFD1_k127_1136079_8 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000008412 179.0
HFD1_k127_1136079_9 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000001464 160.0
HFD1_k127_116168_0 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 389.0
HFD1_k127_116168_1 Aminotransferase class-V K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 392.0
HFD1_k127_116168_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 359.0
HFD1_k127_116168_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00008661 46.0
HFD1_k127_116491_0 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 428.0
HFD1_k127_116491_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 350.0
HFD1_k127_116491_2 Transcriptional regulator K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 348.0
HFD1_k127_116491_3 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 325.0
HFD1_k127_116491_4 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004399 222.0
HFD1_k127_116491_5 domain, Protein K07277,K07278,K21449 - - 0.000001581 60.0
HFD1_k127_116491_6 - - - - 0.000006427 58.0
HFD1_k127_1178430_0 NADPH:quinone reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 310.0
HFD1_k127_1178430_1 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000003203 222.0
HFD1_k127_1178430_2 glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000002253 143.0
HFD1_k127_117918_0 Protein of unknown function (DUF3616) - - - 0.0000000000000000000000001572 118.0
HFD1_k127_1181810_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 482.0
HFD1_k127_119941_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 479.0
HFD1_k127_119941_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000007394 211.0
HFD1_k127_1203827_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.682e-287 897.0
HFD1_k127_1203827_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006444 231.0
HFD1_k127_1203827_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000006895 220.0
HFD1_k127_1203827_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000008075 88.0
HFD1_k127_1203827_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000007049 49.0
HFD1_k127_1203830_0 Sodium:solute symporter family - - - 5.456e-279 871.0
HFD1_k127_1203830_1 PFAM Amidase - - - 4.059e-271 845.0
HFD1_k127_1203830_10 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 446.0
HFD1_k127_1203830_11 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 355.0
HFD1_k127_1203830_12 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 313.0
HFD1_k127_1203830_13 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 313.0
HFD1_k127_1203830_14 RNA polymerase sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001155 255.0
HFD1_k127_1203830_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000009155 235.0
HFD1_k127_1203830_16 PFAM Cupin 2 conserved barrel domain protein K05913 - 1.13.11.41 0.000000000000000000000000000000000000000000000002644 178.0
HFD1_k127_1203830_17 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000001392 154.0
HFD1_k127_1203830_18 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000001258 145.0
HFD1_k127_1203830_19 PFAM glycine cleavage H-protein - - - 0.00000000000000000000000000000063 134.0
HFD1_k127_1203830_2 efflux transmembrane transporter activity K02004 - - 4.186e-213 688.0
HFD1_k127_1203830_20 Glycine cleavage H-protein - - - 0.000000000000000000000000313 113.0
HFD1_k127_1203830_21 - - - - 0.00000000000000000000000427 106.0
HFD1_k127_1203830_22 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000001167 88.0
HFD1_k127_1203830_24 - - - - 0.000004929 52.0
HFD1_k127_1203830_25 protein kinase activity - - - 0.0000585 47.0
HFD1_k127_1203830_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 619.0
HFD1_k127_1203830_4 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 601.0
HFD1_k127_1203830_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 605.0
HFD1_k127_1203830_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 568.0
HFD1_k127_1203830_7 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 547.0
HFD1_k127_1203830_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 468.0
HFD1_k127_1203830_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 465.0
HFD1_k127_1205826_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1017.0
HFD1_k127_1205826_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 2.864e-227 726.0
HFD1_k127_1205826_10 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000002217 230.0
HFD1_k127_1205826_11 TipAS antibiotic-recognition domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009442 227.0
HFD1_k127_1205826_12 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000547 214.0
HFD1_k127_1205826_13 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000003485 217.0
HFD1_k127_1205826_14 succinate dehydrogenase K00241,K00247 - - 0.00000000000000000000000000000000000000000000000000008246 196.0
HFD1_k127_1205826_15 Membrane - - - 0.000000000000000000000000000000000000000000000000000554 210.0
HFD1_k127_1205826_16 - - - - 0.00000000000000000000000000000000000002698 147.0
HFD1_k127_1205826_17 Rhodanese Homology Domain - - - 0.0000000000000000000000000000001939 130.0
HFD1_k127_1205826_18 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000002125 136.0
HFD1_k127_1205826_19 - - - - 0.000000000000000000000000000006072 121.0
HFD1_k127_1205826_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 6.632e-199 648.0
HFD1_k127_1205826_20 Beta-lactamase - - - 0.000000000000001203 78.0
HFD1_k127_1205826_21 Beta-lactamase - - - 0.0000000000002416 74.0
HFD1_k127_1205826_22 Protein of unknown function (DUF3108) - - - 0.0000000000004895 79.0
HFD1_k127_1205826_3 Amidohydrolase family - - - 8.702e-195 638.0
HFD1_k127_1205826_4 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 503.0
HFD1_k127_1205826_5 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 374.0
HFD1_k127_1205826_6 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 340.0
HFD1_k127_1205826_7 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 338.0
HFD1_k127_1205826_8 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 295.0
HFD1_k127_1205826_9 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006174 273.0
HFD1_k127_121007_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000004588 199.0
HFD1_k127_121007_1 electron transfer activity - - - 0.00000000000000000000000000000000000000000000006056 186.0
HFD1_k127_121007_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000001538 168.0
HFD1_k127_121007_3 ECF sigma factor - - - 0.00000000000000000000000000003238 119.0
HFD1_k127_121007_5 Transposase DDE domain - - - 0.000000000009369 70.0
HFD1_k127_121007_6 Helix-turn-helix domain - - - 0.0000008603 53.0
HFD1_k127_1215980_0 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 321.0
HFD1_k127_1215980_1 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000813 280.0
HFD1_k127_1215980_2 Prolyl oligopeptidase family - - - 0.00000000000000001377 83.0
HFD1_k127_1234984_0 response to abiotic stimulus K03086,K06867,K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 415.0
HFD1_k127_1256838_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 500.0
HFD1_k127_1256838_1 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 369.0
HFD1_k127_1256838_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000001222 161.0
HFD1_k127_1256838_3 - - - - 0.000000008745 57.0
HFD1_k127_1263888_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.487e-227 734.0
HFD1_k127_1263888_1 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 315.0
HFD1_k127_1263888_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002371 255.0
HFD1_k127_1263888_3 regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000254 241.0
HFD1_k127_1263888_4 ECF sigma factor - - - 0.0000747 47.0
HFD1_k127_1271748_0 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 492.0
HFD1_k127_1271748_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 383.0
HFD1_k127_1271748_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000306 231.0
HFD1_k127_1271748_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000001437 160.0
HFD1_k127_127184_0 nucleic acid binding - - - 0.00000000000000000000000000000000000000000000000000000004895 216.0
HFD1_k127_127184_1 nucleic acid binding - - - 0.000000002025 60.0
HFD1_k127_1289201_0 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000004971 207.0
HFD1_k127_1300690_0 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004419 281.0
HFD1_k127_132931_0 HELICc2 K03722 - 3.6.4.12 2.821e-194 627.0
HFD1_k127_132931_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 609.0
HFD1_k127_132931_10 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
HFD1_k127_132931_11 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 389.0
HFD1_k127_132931_12 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 319.0
HFD1_k127_132931_13 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 286.0
HFD1_k127_132931_14 NAD dependent epimerase/dehydratase family K07535 - - 0.000000000000000000000000000000000000000000000000000000000000000000001277 244.0
HFD1_k127_132931_15 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000002734 234.0
HFD1_k127_132931_16 PFAM microcompartments protein K04027 - - 0.00000000000000000000000000000000003083 139.0
HFD1_k127_132931_17 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000975 147.0
HFD1_k127_132931_18 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.00000000000000000000000000000003331 131.0
HFD1_k127_132931_19 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000009144 122.0
HFD1_k127_132931_2 glycine hydroxymethyltransferase activity K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 570.0
HFD1_k127_132931_21 - - - - 0.000000000000000000002635 105.0
HFD1_k127_132931_23 Domain of Unknown Function (DUF350) - - - 0.000000000000000002329 89.0
HFD1_k127_132931_24 Alpha/beta hydrolase family - - - 0.000000000000000002841 95.0
HFD1_k127_132931_26 Helix-turn-helix domain - - - 0.00000000000005385 83.0
HFD1_k127_132931_27 - - - - 0.0000006053 55.0
HFD1_k127_132931_29 - - - - 0.0001816 53.0
HFD1_k127_132931_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 542.0
HFD1_k127_132931_4 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 520.0
HFD1_k127_132931_5 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 501.0
HFD1_k127_132931_6 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 493.0
HFD1_k127_132931_7 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 490.0
HFD1_k127_132931_8 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 454.0
HFD1_k127_132931_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 431.0
HFD1_k127_1390923_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 467.0
HFD1_k127_1392_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1354.0
HFD1_k127_1392_1 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 571.0
HFD1_k127_1392_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000002448 170.0
HFD1_k127_1392_11 protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000000000000000000000009821 154.0
HFD1_k127_1392_12 Cation transport regulator - - - 0.00000000000000000000000000000000039 136.0
HFD1_k127_1392_13 - - - - 0.00000000000000000007864 104.0
HFD1_k127_1392_14 - - - - 0.000000000000000002144 85.0
HFD1_k127_1392_15 - - - - 0.00000000000000003682 86.0
HFD1_k127_1392_17 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000001269 89.0
HFD1_k127_1392_18 ErfK YbiS YcfS YnhG family protein - - - 0.000000001026 71.0
HFD1_k127_1392_19 Tfp pilus assembly protein FimV - - - 0.00000001602 67.0
HFD1_k127_1392_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 542.0
HFD1_k127_1392_3 Formate dehydrogenase N, transmembrane K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 434.0
HFD1_k127_1392_4 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 396.0
HFD1_k127_1392_5 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 332.0
HFD1_k127_1392_6 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 307.0
HFD1_k127_1392_7 - - - - 0.0000000000000000000000000000000000000000000000001592 182.0
HFD1_k127_1392_8 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000001155 181.0
HFD1_k127_1392_9 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000004986 170.0
HFD1_k127_1399056_0 PQQ enzyme repeat K00114 - 1.1.2.8 8.328e-293 909.0
HFD1_k127_1399056_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 2.222e-286 892.0
HFD1_k127_1399056_10 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 500.0
HFD1_k127_1399056_11 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 459.0
HFD1_k127_1399056_12 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 426.0
HFD1_k127_1399056_13 PFAM Transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 398.0
HFD1_k127_1399056_14 cytochrome c oxidase K02351 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 342.0
HFD1_k127_1399056_15 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 327.0
HFD1_k127_1399056_16 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 312.0
HFD1_k127_1399056_17 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003551 279.0
HFD1_k127_1399056_18 Glycosyl hydrolases family 43 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006796 288.0
HFD1_k127_1399056_19 Cytochrome c oxidase subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000228 261.0
HFD1_k127_1399056_2 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 613.0
HFD1_k127_1399056_20 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009707 275.0
HFD1_k127_1399056_21 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000005906 251.0
HFD1_k127_1399056_22 Aldose 1-epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000003426 237.0
HFD1_k127_1399056_23 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000002043 227.0
HFD1_k127_1399056_24 Glyoxalase-like domain K08234 - - 0.00000000000000000000000000000000000000000000000000000002979 199.0
HFD1_k127_1399056_25 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000001912 193.0
HFD1_k127_1399056_26 PFAM Cytochrome C K00406 - - 0.00000000000000000000000000000000000000000000000002347 184.0
HFD1_k127_1399056_27 PFAM PRC-barrel domain - - - 0.000000000000000000000000000000000000699 142.0
HFD1_k127_1399056_28 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000477 136.0
HFD1_k127_1399056_29 - - - - 0.0000000000000000000000000002367 117.0
HFD1_k127_1399056_3 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 567.0
HFD1_k127_1399056_30 - - - - 0.0000000000000000000000000009506 126.0
HFD1_k127_1399056_31 SnoaL-like domain - - - 0.0000000000000000000000002473 107.0
HFD1_k127_1399056_32 Serine aminopeptidase, S33 - - - 0.0000000000000000000006199 99.0
HFD1_k127_1399056_33 lysyltransferase activity K07027 - - 0.000000000000003196 89.0
HFD1_k127_1399056_34 - - - - 0.00000000000007962 82.0
HFD1_k127_1399056_35 Putative peptidoglycan binding domain - - - 0.000000000002306 80.0
HFD1_k127_1399056_36 - - - - 0.000000000002812 73.0
HFD1_k127_1399056_37 SnoaL-like domain - - - 0.000000000003527 70.0
HFD1_k127_1399056_38 NmrA-like family - - - 0.00000000008395 68.0
HFD1_k127_1399056_39 Belongs to the peptidase S41A family - - - 0.0000000007154 62.0
HFD1_k127_1399056_4 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 554.0
HFD1_k127_1399056_40 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.00000001611 64.0
HFD1_k127_1399056_41 Autotransporter beta-domain - - - 0.000009473 59.0
HFD1_k127_1399056_42 - - - - 0.00009212 50.0
HFD1_k127_1399056_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 522.0
HFD1_k127_1399056_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 518.0
HFD1_k127_1399056_7 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 512.0
HFD1_k127_1399056_8 beta-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 497.0
HFD1_k127_1399056_9 beta-glucosidase activity K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 492.0
HFD1_k127_140699_0 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 445.0
HFD1_k127_140699_1 PFAM Pyrrolo-quinoline quinone - - - 0.000000000000000005855 85.0
HFD1_k127_140699_2 Cytochrome c - - - 0.00000000000004859 83.0
HFD1_k127_140699_3 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00001867 56.0
HFD1_k127_1422892_0 Putative transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 510.0
HFD1_k127_1422892_1 phage integrase domain protein SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
HFD1_k127_1422892_2 COG1064 Zn-dependent alcohol K13979 - - 0.0000000000000000000000000000000001643 135.0
HFD1_k127_1435248_0 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000003728 240.0
HFD1_k127_1504863_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 466.0
HFD1_k127_1510137_0 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000001485 138.0
HFD1_k127_1523677_0 Ribonuclease H protein - - - 0.0000000000000000000000000000000000000000000002374 175.0
HFD1_k127_1523677_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000007705 136.0
HFD1_k127_1527472_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 395.0
HFD1_k127_1527472_1 Helix-turn-helix domain - - - 0.00000009216 58.0
HFD1_k127_1538182_0 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 544.0
HFD1_k127_1538182_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000066 250.0
HFD1_k127_1538182_2 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000008831 248.0
HFD1_k127_154859_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2012.0
HFD1_k127_154859_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2010.0
HFD1_k127_154859_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 306.0
HFD1_k127_154859_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000202 219.0
HFD1_k127_154859_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003978 214.0
HFD1_k127_154859_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000009238 139.0
HFD1_k127_154859_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000004276 137.0
HFD1_k127_154859_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000016 82.0
HFD1_k127_154859_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0002688 48.0
HFD1_k127_157413_0 Transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' - - - 0.0000000000000000000000000000000000000000000000000000000004594 210.0
HFD1_k127_157413_1 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000004815 201.0
HFD1_k127_1612821_0 Carboxypeptidase regulatory-like domain - - - 3.731e-319 1009.0
HFD1_k127_1612821_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.0000000000000000000000000000000000000000000000002661 183.0
HFD1_k127_1612821_2 Fibronectin type 3 domain - - - 0.0000000173 62.0
HFD1_k127_1616591_0 Aldehyde dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0 1364.0
HFD1_k127_1616591_1 Cysteine-rich domain - - - 1.219e-298 932.0
HFD1_k127_1616591_2 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 466.0
HFD1_k127_1616591_3 electron transfer activity K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001098 275.0
HFD1_k127_1616591_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001558 238.0
HFD1_k127_1616591_5 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000001047 191.0
HFD1_k127_1620112_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.025e-314 975.0
HFD1_k127_1620112_1 Carboxypeptidase regulatory-like domain - - - 1.376e-207 684.0
HFD1_k127_1620112_10 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001617 258.0
HFD1_k127_1620112_11 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000007357 185.0
HFD1_k127_1620112_12 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000008307 178.0
HFD1_k127_1620112_13 Rhodanese-like domain - - - 0.00000000000000000000000000000000000007491 150.0
HFD1_k127_1620112_14 - - - - 0.000000000000000000000000000004726 125.0
HFD1_k127_1620112_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000003456 87.0
HFD1_k127_1620112_16 TIGRFAM TonB K03832 - - 0.000000000000001183 89.0
HFD1_k127_1620112_17 - - - - 0.000000000006056 74.0
HFD1_k127_1620112_18 ATP-grasp domain - - - 0.0002654 48.0
HFD1_k127_1620112_2 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 565.0
HFD1_k127_1620112_3 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 540.0
HFD1_k127_1620112_4 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 439.0
HFD1_k127_1620112_5 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 429.0
HFD1_k127_1620112_6 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 418.0
HFD1_k127_1620112_7 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 409.0
HFD1_k127_1620112_8 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 309.0
HFD1_k127_1620112_9 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002188 264.0
HFD1_k127_1622777_0 Vault protein inter-alpha-trypsin domain K07114 - - 1.336e-196 641.0
HFD1_k127_1622777_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000684 194.0
HFD1_k127_1628156_0 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008804 338.0
HFD1_k127_1628156_1 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000002941 90.0
HFD1_k127_1628786_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.913e-301 949.0
HFD1_k127_1628786_1 Prolyl oligopeptidase family - - - 5.57e-271 852.0
HFD1_k127_1628786_10 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 451.0
HFD1_k127_1628786_11 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 451.0
HFD1_k127_1628786_12 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 383.0
HFD1_k127_1628786_13 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 362.0
HFD1_k127_1628786_14 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 353.0
HFD1_k127_1628786_15 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 321.0
HFD1_k127_1628786_16 Domain of unknown function (DUF3471) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003657 280.0
HFD1_k127_1628786_17 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000004803 259.0
HFD1_k127_1628786_18 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002334 252.0
HFD1_k127_1628786_19 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000436 239.0
HFD1_k127_1628786_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 4.218e-198 631.0
HFD1_k127_1628786_20 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000001138 235.0
HFD1_k127_1628786_21 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000005785 230.0
HFD1_k127_1628786_22 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000001589 222.0
HFD1_k127_1628786_23 PFAM FAD dependent oxidoreductase K00301 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000001656 229.0
HFD1_k127_1628786_24 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000004509 209.0
HFD1_k127_1628786_25 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000003385 194.0
HFD1_k127_1628786_26 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000001342 187.0
HFD1_k127_1628786_27 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000442 168.0
HFD1_k127_1628786_28 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000004513 161.0
HFD1_k127_1628786_29 cyclohydrolase K01746 - 4.3.1.4 0.000000000000000000000000000000000005541 145.0
HFD1_k127_1628786_3 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 594.0
HFD1_k127_1628786_30 Uncharacterized conserved protein (DUF2293) - - - 0.0000000000000000000000000000000002264 141.0
HFD1_k127_1628786_31 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.000000000000000000000000001371 125.0
HFD1_k127_1628786_32 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000004629 120.0
HFD1_k127_1628786_33 Lipopolysaccharide-assembly - - - 0.000000000000000000000000009765 117.0
HFD1_k127_1628786_34 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000001092 111.0
HFD1_k127_1628786_35 DUF167 K09131 - - 0.000000000000000000000001741 105.0
HFD1_k127_1628786_36 PFAM GCN5-related N-acetyltransferase K06976 - - 0.00000000000000000000000329 113.0
HFD1_k127_1628786_37 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000005058 102.0
HFD1_k127_1628786_38 Virulence factor BrkB K07058 - - 0.00000000000000001857 93.0
HFD1_k127_1628786_39 PFAM heat shock protein DnaJ domain protein K05516 - - 0.0000000000000001476 89.0
HFD1_k127_1628786_4 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 592.0
HFD1_k127_1628786_40 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000001906 79.0
HFD1_k127_1628786_41 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000001591 75.0
HFD1_k127_1628786_42 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000002988 73.0
HFD1_k127_1628786_43 The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor K13992 - - 0.00000001588 63.0
HFD1_k127_1628786_44 YGGT family K02221 - - 0.0000002981 59.0
HFD1_k127_1628786_45 Uncharacterized conserved protein (DUF2293) - - - 0.00004023 50.0
HFD1_k127_1628786_46 DnaJ homolog subfamily B member - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0010598,GO:0016020,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0098796 - 0.0001356 53.0
HFD1_k127_1628786_5 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 601.0
HFD1_k127_1628786_6 PFAM Peptidase M20 K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 575.0
HFD1_k127_1628786_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 522.0
HFD1_k127_1628786_8 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 503.0
HFD1_k127_1628786_9 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 482.0
HFD1_k127_1635068_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 419.0
HFD1_k127_1647191_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 297.0
HFD1_k127_1647191_1 Cytochrome C and Quinol oxidase polypeptide I K02256 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004736 248.0
HFD1_k127_1647191_2 Cytochrome C and Quinol oxidase polypeptide I K02256 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001603 236.0
HFD1_k127_1647191_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis K00412 - - 0.00000000000000000000003428 111.0
HFD1_k127_1651313_0 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 324.0
HFD1_k127_1651313_1 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000008042 264.0
HFD1_k127_1651313_2 AI-2E family transporter - - - 0.000000000005467 70.0
HFD1_k127_1651313_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0003933 50.0
HFD1_k127_1655686_0 Acyl transferase domain - - - 0.0 3440.0
HFD1_k127_1655686_1 CoA carboxylase activity K00627,K01176,K01966,K03646,K17489 - 2.1.3.1,2.1.3.15,2.3.1.12,3.2.1.1,6.4.1.3 0.0 2254.0
HFD1_k127_1655686_2 acyl-CoA dehydrogenase activity - - - 1.074e-283 880.0
HFD1_k127_1655686_3 GMC oxidoreductase K03333 - 1.1.3.6 2.116e-262 818.0
HFD1_k127_1655686_4 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 527.0
HFD1_k127_1655686_5 fatty acid beta-oxidation using acyl-CoA dehydrogenase K00248,K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006575,GO:0006577,GO:0006579,GO:0006629,GO:0006631,GO:0006635,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009437,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0034641,GO:0036094,GO:0042219,GO:0042413,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:0097164,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 468.0
HFD1_k127_1655686_6 short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 397.0
HFD1_k127_1655686_7 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 325.0
HFD1_k127_1655686_8 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000000004999 215.0
HFD1_k127_1655686_9 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000002855 181.0
HFD1_k127_1656808_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 1.207e-317 995.0
HFD1_k127_1656808_1 Carboxypeptidase regulatory-like domain - - - 1.895e-260 827.0
HFD1_k127_1656808_10 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000001257 208.0
HFD1_k127_1656808_11 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000000000000000000000002683 129.0
HFD1_k127_1656808_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000002218 133.0
HFD1_k127_1656808_13 RNA recognition motif - - - 0.0000000000000000000000000002296 118.0
HFD1_k127_1656808_14 - - - - 0.000000000000000001727 94.0
HFD1_k127_1656808_15 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000002424 91.0
HFD1_k127_1656808_16 - - - - 0.000000000000008507 76.0
HFD1_k127_1656808_17 - - - - 0.0000000000002517 74.0
HFD1_k127_1656808_18 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0003067 53.0
HFD1_k127_1656808_2 tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 597.0
HFD1_k127_1656808_3 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 502.0
HFD1_k127_1656808_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 482.0
HFD1_k127_1656808_5 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 435.0
HFD1_k127_1656808_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 406.0
HFD1_k127_1656808_7 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003173 271.0
HFD1_k127_1656808_8 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009454 265.0
HFD1_k127_1656808_9 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000832 209.0
HFD1_k127_1661580_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 597.0
HFD1_k127_1661580_1 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000008313 160.0
HFD1_k127_1667768_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000004256 228.0
HFD1_k127_1667768_1 - - - - 0.000000000000000000001266 100.0
HFD1_k127_1671947_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.52e-222 698.0
HFD1_k127_1671947_1 Phosphotriesterase K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 537.0
HFD1_k127_1671947_2 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 416.0
HFD1_k127_1671947_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000001154 218.0
HFD1_k127_1676945_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.103e-227 708.0
HFD1_k127_1686006_0 photosystem II stabilization - - - 0.000000000000000281 91.0
HFD1_k127_1699764_0 COG0840 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001958 282.0
HFD1_k127_1699764_1 GYD domain - - - 0.000000000000000000005627 96.0
HFD1_k127_1699764_3 DNA-templated transcription, initiation K02405 - - 0.0000001197 55.0
HFD1_k127_1701125_0 Baseplate J-like protein - - - 0.0 1232.0
HFD1_k127_1701125_1 Phage tail protein (Tail_P2_I) - - - 4.604e-227 727.0
HFD1_k127_1701125_10 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002432 278.0
HFD1_k127_1701125_11 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 261.0
HFD1_k127_1701125_12 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000005249 238.0
HFD1_k127_1701125_13 Tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000002242 230.0
HFD1_k127_1701125_14 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000002491 215.0
HFD1_k127_1701125_15 - - - - 0.00000000000000000000000000000000000000000000000000001616 190.0
HFD1_k127_1701125_16 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000000000000001824 188.0
HFD1_k127_1701125_17 - - - - 0.00000000000000000000000000000000000000000000000001439 192.0
HFD1_k127_1701125_18 Rhs element vgr protein - - - 0.00000000000000000000000000000000000000000000002119 179.0
HFD1_k127_1701125_2 Baseplate J-like protein - - - 6.053e-202 652.0
HFD1_k127_1701125_20 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000004442 175.0
HFD1_k127_1701125_21 PAAR motif - - - 0.000000000000000000000000000000000003147 139.0
HFD1_k127_1701125_22 cheY-homologous receiver domain - - - 0.000000000000000000000000007873 116.0
HFD1_k127_1701125_23 - - - - 0.0000000000000002521 80.0
HFD1_k127_1701125_24 - - - - 0.0000000001951 72.0
HFD1_k127_1701125_25 Evidence 4 Homologs of previously reported genes of - - - 0.000000004827 65.0
HFD1_k127_1701125_3 Late control gene D protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 554.0
HFD1_k127_1701125_4 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 479.0
HFD1_k127_1701125_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 355.0
HFD1_k127_1701125_6 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 338.0
HFD1_k127_1701125_7 phage tail tape measure protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 342.0
HFD1_k127_1701125_8 domain, Protein K15125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 300.0
HFD1_k127_1701125_9 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 301.0
HFD1_k127_1703305_0 transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 398.0
HFD1_k127_1719243_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 4.394e-196 623.0
HFD1_k127_1719243_1 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 516.0
HFD1_k127_1719243_10 - - - - 0.000000499 52.0
HFD1_k127_1719243_11 Sporulation related domain - - - 0.000007929 58.0
HFD1_k127_1719243_2 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 322.0
HFD1_k127_1719243_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000001751 248.0
HFD1_k127_1719243_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000002827 214.0
HFD1_k127_1719243_5 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000001249 212.0
HFD1_k127_1719243_6 PFAM peptidase K16922 - - 0.000000000000000000000000000000000000000000000000000001116 218.0
HFD1_k127_1719243_7 Protein kinase domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000000217 200.0
HFD1_k127_1719243_8 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000003388 128.0
HFD1_k127_1719243_9 PilZ domain K02676 - - 0.0000004804 57.0
HFD1_k127_1720477_0 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000001697 173.0
HFD1_k127_1720477_1 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000002852 161.0
HFD1_k127_1720477_2 phage tail tape measure protein - - - 0.00000000000007295 79.0
HFD1_k127_1721655_0 Peptidase M14, carboxypeptidase A - - - 0.0 1502.0
HFD1_k127_1721655_1 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 1.691e-258 812.0
HFD1_k127_1721655_2 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 5.167e-214 681.0
HFD1_k127_1721655_3 - - - - 0.00000007454 61.0
HFD1_k127_1721878_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000001023 181.0
HFD1_k127_1721878_1 Polysaccharide biosynthesis/export protein - - - 0.00000000506 63.0
HFD1_k127_172893_0 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 493.0
HFD1_k127_172893_1 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 471.0
HFD1_k127_172893_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 321.0
HFD1_k127_172893_3 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000003742 196.0
HFD1_k127_172893_4 Prenyltransferase and squalene oxidase repeat - - - 0.000000000000000000000000000000000003366 149.0
HFD1_k127_172893_5 Sulfurtransferase TusA - - - 0.000000000000001024 82.0
HFD1_k127_1733347_0 Tricorn protease C1 domain K08676 - - 0.0 1272.0
HFD1_k127_1733347_1 Protein export membrane protein K03296,K18138 - - 0.0 1240.0
HFD1_k127_1733347_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 362.0
HFD1_k127_1733347_11 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 303.0
HFD1_k127_1733347_12 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007738 269.0
HFD1_k127_1733347_13 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000003747 269.0
HFD1_k127_1733347_14 - - - - 0.00000000000000000000000000000000000000000000001106 180.0
HFD1_k127_1733347_15 - - - - 0.00000000000000000000000000000000000000005057 157.0
HFD1_k127_1733347_16 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000005408 149.0
HFD1_k127_1733347_17 PIN domain - - - 0.000000000000000000005206 99.0
HFD1_k127_1733347_18 domain protein - - - 0.00000000000000001796 84.0
HFD1_k127_1733347_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 4.349e-237 752.0
HFD1_k127_1733347_20 toxin-antitoxin pair type II binding - - - 0.00001029 52.0
HFD1_k127_1733347_3 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 3.049e-211 676.0
HFD1_k127_1733347_4 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 619.0
HFD1_k127_1733347_5 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 572.0
HFD1_k127_1733347_6 alcohol dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 540.0
HFD1_k127_1733347_7 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 525.0
HFD1_k127_1733347_8 enterobactin catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 511.0
HFD1_k127_1733347_9 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 477.0
HFD1_k127_1743130_0 manually curated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 303.0
HFD1_k127_1745963_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 569.0
HFD1_k127_1745963_1 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 537.0
HFD1_k127_1745963_2 choline dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 533.0
HFD1_k127_1745963_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 492.0
HFD1_k127_1745963_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 424.0
HFD1_k127_1745963_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 281.0
HFD1_k127_1745963_6 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000005032 252.0
HFD1_k127_1745963_7 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000002031 198.0
HFD1_k127_1745963_8 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000004958 197.0
HFD1_k127_1745963_9 metallopeptidase activity K08738,K20276 - - 0.000000000000000000000005645 112.0
HFD1_k127_175899_0 GTP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 425.0
HFD1_k127_1767814_0 DDE superfamily endonuclease K07494 - - 0.0000000000000000000000000000000000000000000000000000000000000002058 224.0
HFD1_k127_1767814_1 Transposase K07499 - - 0.0000000000000000000000000000000000000000000000000000000000001031 216.0
HFD1_k127_1769675_0 Peptidase C39 family K06147 - - 1.381e-287 910.0
HFD1_k127_1769675_1 ABC transporter, ATP-binding protein - - - 4.138e-194 628.0
HFD1_k127_1769675_2 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 302.0
HFD1_k127_1769675_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000005572 220.0
HFD1_k127_1778059_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 579.0
HFD1_k127_1778059_1 isochorismatase - - - 0.0000000000000000000000000000000000000006602 155.0
HFD1_k127_1785180_0 Subtilase family K14645 GO:0005575,GO:0005576 - 0.000000000000000000000000000000002915 136.0
HFD1_k127_1785180_1 DinB family - - - 0.000000000000000000000000157 113.0
HFD1_k127_1785180_2 methylisocitrate lyase activity K03417 - 4.1.3.30 0.0000000000000006895 81.0
HFD1_k127_1786945_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000000000000000000000000000000000001609 167.0
HFD1_k127_178786_0 domain protein - - - 0.0 1153.0
HFD1_k127_178786_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 641.0
HFD1_k127_178786_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 449.0
HFD1_k127_178786_3 Protein of unknown function (DUF3179) - - - 0.00000000000000000000000000000000000000000000000008338 185.0
HFD1_k127_178786_4 - - - - 0.000000000000000000000000000000000000000001485 158.0
HFD1_k127_178786_5 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000001326 131.0
HFD1_k127_178786_6 Cytochrome c554 and c-prime - - - 0.000000000000000000002948 101.0
HFD1_k127_178786_7 Protein of unknown function (DUF3179) - - - 0.00000000006317 70.0
HFD1_k127_1792844_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001203 279.0
HFD1_k127_1807973_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.824e-315 995.0
HFD1_k127_1807973_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.438e-203 642.0
HFD1_k127_1807973_10 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000496 269.0
HFD1_k127_1807973_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000001881 233.0
HFD1_k127_1807973_12 oxidoreductase activity K12511 - - 0.0000000000000000000000000000000000000000000000000000000000003803 226.0
HFD1_k127_1807973_13 lactoylglutathione lyase activity K11210,K21253,K21264,K21265 GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 2.5.1.18 0.000000000000000000000000000000000000000000000000001082 186.0
HFD1_k127_1807973_14 oxidoreductase activity K12511 - - 0.00000000000000000000000000000000000000000000007699 182.0
HFD1_k127_1807973_15 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000001605 164.0
HFD1_k127_1807973_16 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.000000000000000000000000000003187 129.0
HFD1_k127_1807973_17 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000001139 122.0
HFD1_k127_1807973_18 von Willebrand factor, type A K07114 - - 0.0000000000000000000000001306 118.0
HFD1_k127_1807973_19 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000001637 105.0
HFD1_k127_1807973_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 576.0
HFD1_k127_1807973_20 general stress protein - - - 0.00000004351 60.0
HFD1_k127_1807973_21 CYTH K01768 - 4.6.1.1 0.00000006702 61.0
HFD1_k127_1807973_3 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 514.0
HFD1_k127_1807973_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 512.0
HFD1_k127_1807973_5 Amidohydrolase family K01465,K06015 - 3.5.1.81,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 505.0
HFD1_k127_1807973_6 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 470.0
HFD1_k127_1807973_7 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 435.0
HFD1_k127_1807973_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 307.0
HFD1_k127_1807973_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001917 276.0
HFD1_k127_1810047_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000002225 226.0
HFD1_k127_1810047_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.00000000000000000000000000000000000000000000000000000000001218 214.0
HFD1_k127_1825360_0 transport - - - 5.11e-312 990.0
HFD1_k127_1825360_1 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 3.703e-200 639.0
HFD1_k127_1825360_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000007935 102.0
HFD1_k127_1825360_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000007464 88.0
HFD1_k127_1825360_12 Carboxypeptidase regulatory-like domain - - - 0.000000000000001484 91.0
HFD1_k127_1825360_13 - - - - 0.000000000008705 73.0
HFD1_k127_1825360_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0002535 53.0
HFD1_k127_1825360_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 392.0
HFD1_k127_1825360_3 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 374.0
HFD1_k127_1825360_4 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002972 221.0
HFD1_k127_1825360_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000001242 199.0
HFD1_k127_1825360_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000007321 145.0
HFD1_k127_1825360_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000000000004288 149.0
HFD1_k127_1825360_8 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000002359 95.0
HFD1_k127_1825360_9 domain protein K14194 - - 0.00000000000000000001281 107.0
HFD1_k127_1825482_0 PFAM Transposase, Rhodopirellula-type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 381.0
HFD1_k127_1829969_0 - - - - 0.00000000000000000000000000000001752 131.0
HFD1_k127_1847256_0 Belongs to the xylose isomerase family K01805 - 5.3.1.5 2.207e-197 621.0
HFD1_k127_1854962_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 400.0
HFD1_k127_1854962_1 unidirectional conjugation K03205 - - 0.00000000002364 71.0
HFD1_k127_1865171_0 Tetratricopeptide repeat - - - 0.000003198 55.0
HFD1_k127_1869812_0 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005113 263.0
HFD1_k127_1869812_1 CoA binding domain K06929 - - 0.000000000000000000001282 97.0
HFD1_k127_1869812_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00001324 50.0
HFD1_k127_1892223_0 COG0675 Transposase and inactivated derivatives K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 428.0
HFD1_k127_1896046_0 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000215 126.0
HFD1_k127_1897929_0 efflux transmembrane transporter activity - - - 3.327e-229 734.0
HFD1_k127_1897929_1 efflux transmembrane transporter activity K02004 - - 5.979e-213 691.0
HFD1_k127_1897929_10 Putative adhesin - - - 0.0000000000000000000000000000000001977 141.0
HFD1_k127_1897929_11 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000002494 115.0
HFD1_k127_1897929_12 efflux transmembrane transporter activity K02004 - - 0.00000000000014 75.0
HFD1_k127_1897929_14 outer membrane protein protective antigen - - - 0.000000005914 68.0
HFD1_k127_1897929_15 - - - - 0.00000005374 61.0
HFD1_k127_1897929_17 efflux transmembrane transporter activity - - - 0.00001427 48.0
HFD1_k127_1897929_18 MacB-like periplasmic core domain - - - 0.00002083 47.0
HFD1_k127_1897929_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 604.0
HFD1_k127_1897929_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 442.0
HFD1_k127_1897929_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 365.0
HFD1_k127_1897929_5 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 332.0
HFD1_k127_1897929_6 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000009577 212.0
HFD1_k127_1897929_7 - - - - 0.0000000000000000000000000000000000000000000000000000001101 208.0
HFD1_k127_1897929_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000001766 177.0
HFD1_k127_1897929_9 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000003373 178.0
HFD1_k127_1903709_0 Cytochrome c554 and c-prime - - - 1.01e-256 806.0
HFD1_k127_1912371_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1134.0
HFD1_k127_1912371_1 Amidohydrolase family - - - 0.0 1041.0
HFD1_k127_1912371_10 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 444.0
HFD1_k127_1912371_11 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 438.0
HFD1_k127_1912371_12 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 429.0
HFD1_k127_1912371_13 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 383.0
HFD1_k127_1912371_14 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 380.0
HFD1_k127_1912371_15 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 364.0
HFD1_k127_1912371_16 Lycopene cyclase protein K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 336.0
HFD1_k127_1912371_17 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 343.0
HFD1_k127_1912371_18 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 321.0
HFD1_k127_1912371_19 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 327.0
HFD1_k127_1912371_2 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 4.865e-290 911.0
HFD1_k127_1912371_20 prohibitin homologues - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 306.0
HFD1_k127_1912371_21 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 304.0
HFD1_k127_1912371_22 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 286.0
HFD1_k127_1912371_23 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 303.0
HFD1_k127_1912371_24 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000004302 276.0
HFD1_k127_1912371_25 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002138 272.0
HFD1_k127_1912371_26 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004943 253.0
HFD1_k127_1912371_27 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001014 256.0
HFD1_k127_1912371_28 Domain of unknown function (DUF4922) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004269 255.0
HFD1_k127_1912371_29 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000003512 241.0
HFD1_k127_1912371_3 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 4.024e-260 820.0
HFD1_k127_1912371_30 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000005289 242.0
HFD1_k127_1912371_31 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000000000001231 224.0
HFD1_k127_1912371_32 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000001126 215.0
HFD1_k127_1912371_33 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000003134 220.0
HFD1_k127_1912371_34 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000646 228.0
HFD1_k127_1912371_35 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000009402 216.0
HFD1_k127_1912371_36 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K03585 - - 0.0000000000000000000000000000000000000000000000000000000003399 218.0
HFD1_k127_1912371_37 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000001879 214.0
HFD1_k127_1912371_38 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000001288 198.0
HFD1_k127_1912371_39 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000001552 180.0
HFD1_k127_1912371_4 Carbon starvation protein K06200 - - 4.492e-214 681.0
HFD1_k127_1912371_40 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000007267 187.0
HFD1_k127_1912371_41 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000005211 179.0
HFD1_k127_1912371_42 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000000007518 169.0
HFD1_k127_1912371_43 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000004412 168.0
HFD1_k127_1912371_44 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000802 167.0
HFD1_k127_1912371_45 AAA domain - - - 0.00000000000000000000000000000000000009367 150.0
HFD1_k127_1912371_46 - - - - 0.000000000000000000000000000000000007052 150.0
HFD1_k127_1912371_47 - - - - 0.0000000000000000000000000000000001004 141.0
HFD1_k127_1912371_49 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000001285 121.0
HFD1_k127_1912371_5 PFAM Type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 514.0
HFD1_k127_1912371_50 - - - - 0.000000000000000000000000634 108.0
HFD1_k127_1912371_51 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000001563 106.0
HFD1_k127_1912371_52 Protein of unknown function (DUF1460) - - - 0.00000000000000000002022 100.0
HFD1_k127_1912371_53 hyperosmotic response K04065 - - 0.000000000000000001643 95.0
HFD1_k127_1912371_54 Frataxin-like domain K06202 - - 0.000000000000000006975 87.0
HFD1_k127_1912371_55 NfeD-like C-terminal, partner-binding - - - 0.0000000000000001566 87.0
HFD1_k127_1912371_56 Ankyrin 1, erythrocytic K10380,K15502,K15503 - - 0.000000000000001526 83.0
HFD1_k127_1912371_58 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000001437 83.0
HFD1_k127_1912371_59 - - - - 0.000000000001068 74.0
HFD1_k127_1912371_6 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 495.0
HFD1_k127_1912371_60 Molecular chaperone - - - 0.000000000001903 76.0
HFD1_k127_1912371_61 Acetyltransferase (GNAT) domain - - - 0.00000002615 62.0
HFD1_k127_1912371_64 Prokaryotic N-terminal methylation motif K02650 - - 0.0002259 52.0
HFD1_k127_1912371_65 - - - - 0.0005322 47.0
HFD1_k127_1912371_7 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 496.0
HFD1_k127_1912371_8 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 505.0
HFD1_k127_1912371_9 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 471.0
HFD1_k127_1950282_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004613 276.0
HFD1_k127_1950282_1 response regulator K07685 - - 0.00000000000000000000000000000000000000000000003354 178.0
HFD1_k127_1952327_0 Dienelactone hydrolase family - - - 3.67e-293 913.0
HFD1_k127_1952327_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 516.0
HFD1_k127_1952327_10 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000007366 230.0
HFD1_k127_1952327_11 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000001255 185.0
HFD1_k127_1952327_12 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000006236 169.0
HFD1_k127_1952327_13 Ribosomal protein L19 K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000008639 158.0
HFD1_k127_1952327_14 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000002513 156.0
HFD1_k127_1952327_15 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000000000006137 122.0
HFD1_k127_1952327_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000000000309 114.0
HFD1_k127_1952327_17 Ribosomal protein S16 K02959 - - 0.000000000000000000000003131 105.0
HFD1_k127_1952327_18 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000002879 98.0
HFD1_k127_1952327_19 PFAM SNARE associated Golgi protein - - - 0.0000000000000000007247 95.0
HFD1_k127_1952327_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 484.0
HFD1_k127_1952327_20 Tetratricopeptide repeat - - - 0.00000000000000002572 85.0
HFD1_k127_1952327_21 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000004039 89.0
HFD1_k127_1952327_22 Tetratricopeptide repeat K06665 GO:0000122,GO:0000228,GO:0000785,GO:0000790,GO:0000988,GO:0000989,GO:0001076,GO:0001190,GO:0001191,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006139,GO:0006323,GO:0006325,GO:0006333,GO:0006338,GO:0006342,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016458,GO:0016584,GO:0017053,GO:0018130,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031497,GO:0031974,GO:0031981,GO:0032774,GO:0032879,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0034728,GO:0035950,GO:0035952,GO:0035953,GO:0035955,GO:0040029,GO:0042304,GO:0042826,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0045814,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046890,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0060255,GO:0062012,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0072364,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090088,GO:0090089,GO:0090304,GO:0090568,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000531,GO:2000877,GO:2000879,GO:2001020,GO:2001141 - 0.00000000000001717 85.0
HFD1_k127_1952327_23 G5 domain protein - - - 0.00000000000007749 79.0
HFD1_k127_1952327_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 472.0
HFD1_k127_1952327_4 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 451.0
HFD1_k127_1952327_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 338.0
HFD1_k127_1952327_6 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 345.0
HFD1_k127_1952327_7 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 288.0
HFD1_k127_1952327_8 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001855 276.0
HFD1_k127_1952327_9 amine dehydrogenase activity K14647,K21449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001002 271.0
HFD1_k127_1988014_0 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 597.0
HFD1_k127_1988014_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961,K01965,K01968 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 574.0
HFD1_k127_1988014_2 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 497.0
HFD1_k127_1988014_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 417.0
HFD1_k127_1988014_4 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 327.0
HFD1_k127_1988014_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 299.0
HFD1_k127_1988014_6 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000002846 197.0
HFD1_k127_1988014_7 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000002718 189.0
HFD1_k127_1988014_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000003907 108.0
HFD1_k127_1996495_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 555.0
HFD1_k127_1996495_1 Periplasmic protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 516.0
HFD1_k127_1996495_10 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000002936 203.0
HFD1_k127_1996495_11 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000005417 186.0
HFD1_k127_1996495_12 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000001545 147.0
HFD1_k127_1996495_13 TIR domain - - - 0.00000000000000000000000000005547 123.0
HFD1_k127_1996495_14 Tyrosine phosphatase family - - - 0.00000000000000000000003164 108.0
HFD1_k127_1996495_15 PFAM peptidase S16 lon domain protein K07157 - - 0.000000000000000000001183 104.0
HFD1_k127_1996495_16 DNA-templated transcription, initiation K03088 - - 0.0000000000000000004091 96.0
HFD1_k127_1996495_17 transferase activity, transferring glycosyl groups - - - 0.000000000000005733 87.0
HFD1_k127_1996495_18 - - - - 0.00000000000005262 82.0
HFD1_k127_1996495_19 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000006845 74.0
HFD1_k127_1996495_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 399.0
HFD1_k127_1996495_20 O-Antigen ligase - - - 0.00000000008505 75.0
HFD1_k127_1996495_21 - - - - 0.0007563 48.0
HFD1_k127_1996495_3 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 376.0
HFD1_k127_1996495_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 298.0
HFD1_k127_1996495_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004524 300.0
HFD1_k127_1996495_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001224 271.0
HFD1_k127_1996495_7 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001303 248.0
HFD1_k127_1996495_8 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
HFD1_k127_1996495_9 - - - - 0.0000000000000000000000000000000000000000000000000000000001611 210.0
HFD1_k127_2000445_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02256 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.9.3.1 0.000000000008344 67.0
HFD1_k127_2013140_0 transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 449.0
HFD1_k127_2013140_1 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000002664 126.0
HFD1_k127_2013140_2 DDE superfamily endonuclease - - - 0.000000000000945 70.0
HFD1_k127_2017040_0 efflux transmembrane transporter activity K02004 - - 1.732e-200 652.0
HFD1_k127_2017040_1 Beta-lactamase class C and other penicillin binding K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 306.0
HFD1_k127_2017040_2 - - - - 0.0000000000000000000000000000000000000000000000000000000001993 209.0
HFD1_k127_2017040_3 Tricorn protease homolog - - - 0.000000000000000000000000000000000000000009446 155.0
HFD1_k127_2038920_0 polysaccharide biosynthetic process K06409 - - 0.000000000000000000000000000000000000000000000000000000000000008839 232.0
HFD1_k127_2042352_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 326.0
HFD1_k127_2051393_0 acetyltransferase - - - 0.0000000000000000000000000000000000000000000001604 177.0
HFD1_k127_2051393_1 Calcineurin-like phosphoesterase K07098 - - 0.0001857 44.0
HFD1_k127_2058306_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 500.0
HFD1_k127_2058306_1 thiamine-containing compound biosynthetic process K02051 - - 0.000006772 52.0
HFD1_k127_2058378_0 similarity to SP Q54513 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 332.0
HFD1_k127_2058378_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000007049 49.0
HFD1_k127_2088600_0 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 467.0
HFD1_k127_2088600_1 Enoyl-(Acyl carrier protein) reductase K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000745 66.0
HFD1_k127_2098711_0 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000385 271.0
HFD1_k127_2114073_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 6.768e-287 888.0
HFD1_k127_2114073_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 2.024e-238 756.0
HFD1_k127_2114073_10 O-methyltransferase activity K00543,K13169 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008172,GO:0008757,GO:0009058,GO:0009059,GO:0009308,GO:0009309,GO:0009987,GO:0010467,GO:0010817,GO:0016740,GO:0016741,GO:0017096,GO:0017144,GO:0018130,GO:0019438,GO:0019538,GO:0030186,GO:0030187,GO:0032259,GO:0034641,GO:0034645,GO:0034754,GO:0042401,GO:0042430,GO:0042435,GO:0042445,GO:0042446,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046483,GO:0046983,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1905939,GO:1905940,GO:2000018,GO:2000019,GO:2000026,GO:2000241,GO:2000242 2.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000007023 257.0
HFD1_k127_2114073_11 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000003908 190.0
HFD1_k127_2114073_12 YCII-related domain - - - 0.0000000000000000000000000000000005796 131.0
HFD1_k127_2114073_14 Forkhead associated domain - - - 0.0000000000000000000000000004038 129.0
HFD1_k127_2114073_15 Glyoxalase-like domain - - - 0.000000000000000000003466 96.0
HFD1_k127_2114073_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000002917 83.0
HFD1_k127_2114073_17 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000005248 78.0
HFD1_k127_2114073_18 - - - - 0.000005754 49.0
HFD1_k127_2114073_2 Sigma-70 region 2 K03088 - - 2.083e-225 708.0
HFD1_k127_2114073_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.248e-224 715.0
HFD1_k127_2114073_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 579.0
HFD1_k127_2114073_5 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 437.0
HFD1_k127_2114073_6 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 307.0
HFD1_k127_2114073_7 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 300.0
HFD1_k127_2114073_8 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 283.0
HFD1_k127_2114073_9 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 274.0
HFD1_k127_2140539_0 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000000000000000000000009332 146.0
HFD1_k127_2140539_1 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000004375 96.0
HFD1_k127_2140539_2 ORF located using Blastx - - - 0.000000000000001573 77.0
HFD1_k127_2140539_3 - - - - 0.00000000000002491 74.0
HFD1_k127_2140539_4 - - - - 0.000000000005295 67.0
HFD1_k127_2140539_5 - - - - 0.0000000001046 63.0
HFD1_k127_2140539_6 - - - - 0.0000001316 53.0
HFD1_k127_2140539_8 - - - - 0.00006289 46.0
HFD1_k127_2140539_9 - - - - 0.0001086 45.0
HFD1_k127_2144867_0 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 320.0
HFD1_k127_2144867_1 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002118 273.0
HFD1_k127_2144867_2 - - - - 0.0000000000000000006509 94.0
HFD1_k127_2144867_3 - - - - 0.000000000000008146 81.0
HFD1_k127_2144867_4 Belongs to the 'phage' integrase family - - - 0.0000006176 57.0
HFD1_k127_214793_0 Beta galactosidase small chain K01190 - 3.2.1.23 0.0 1272.0
HFD1_k127_214793_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000007044 56.0
HFD1_k127_214891_0 glucose-6-phosphate isomerase activity K01810 - 5.3.1.9 6.853e-203 636.0
HFD1_k127_2208279_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 462.0
HFD1_k127_2208279_1 Transcriptional regulatory protein, C terminal - - - 0.000000002856 58.0
HFD1_k127_2258369_0 cellulose 1,4-beta-cellobiosidase activity - - - 0.0007466 49.0
HFD1_k127_2313583_0 IS30 family K07482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 381.0
HFD1_k127_2317091_0 DDE superfamily endonuclease K07494 - - 0.000000000000000000000000000000000000000000000000000000000000008656 220.0
HFD1_k127_2317091_1 Transposase K07492 - - 0.000000000000000000000000000000304 126.0
HFD1_k127_2317091_2 PFAM Transposase, Synechocystis PCC 6803 K07494 - - 0.0000000000000000007155 90.0
HFD1_k127_2317091_3 NERD domain protein - - - 0.00000000000002333 76.0
HFD1_k127_2351699_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.12e-202 633.0
HFD1_k127_2378602_0 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 578.0
HFD1_k127_2420644_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 467.0
HFD1_k127_2420644_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 343.0
HFD1_k127_2420644_10 Two component signalling adaptor domain K03408 - - 0.0000000006316 66.0
HFD1_k127_2420644_11 - - - - 0.00000000127 63.0
HFD1_k127_2420644_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 347.0
HFD1_k127_2420644_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 341.0
HFD1_k127_2420644_4 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 302.0
HFD1_k127_2420644_5 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000004004 217.0
HFD1_k127_2420644_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000002592 197.0
HFD1_k127_2420644_7 membrane protein (homolog of Drosophila rhomboid) K19225 - 3.4.21.105 0.0000000000000000000000000000000000000002002 166.0
HFD1_k127_2420644_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000003267 133.0
HFD1_k127_2420644_9 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000004588 111.0
HFD1_k127_2427052_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 584.0
HFD1_k127_2427052_1 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 356.0
HFD1_k127_2427052_2 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 352.0
HFD1_k127_2427052_3 - - - - 0.000000000000000000000000000000000000000000000005727 186.0
HFD1_k127_2427052_5 FMN biosynthetic process K01091,K07732 - 2.7.1.161,3.1.3.18 0.0007563 44.0
HFD1_k127_2428171_0 TIGRFAM TonB K03832 - - 0.0000000000005135 79.0
HFD1_k127_2428171_1 Belongs to the ompA family - - - 0.000001117 52.0
HFD1_k127_2449399_0 Protein of unknown function (DUF521) K09123 - - 1.369e-212 669.0
HFD1_k127_2449399_1 Protein of unknown function DUF126 K09123,K09128 - - 0.0000000000000000000001961 97.0
HFD1_k127_2449399_2 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.00003657 46.0
HFD1_k127_245118_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 333.0
HFD1_k127_245118_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000151 181.0
HFD1_k127_2452813_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.464e-237 741.0
HFD1_k127_2452813_1 amino acid K03294 - - 3.004e-218 690.0
HFD1_k127_2452813_10 COG1078 HD superfamily phosphohydrolases K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 311.0
HFD1_k127_2452813_11 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002694 275.0
HFD1_k127_2452813_12 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001417 262.0
HFD1_k127_2452813_13 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000002493 246.0
HFD1_k127_2452813_14 PFAM ParB domain protein nuclease K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
HFD1_k127_2452813_15 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000000000001048 196.0
HFD1_k127_2452813_16 PFAM Response regulator receiver domain K02483,K18344 - - 0.00000000000000000000000000000000000000000000000000000766 197.0
HFD1_k127_2452813_17 - - - - 0.00000000000000000000000000000000000000000000000000002992 204.0
HFD1_k127_2452813_18 Phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000005882 193.0
HFD1_k127_2452813_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001692 189.0
HFD1_k127_2452813_2 AAA ATPase domain K12132 - 2.7.11.1 2.547e-203 675.0
HFD1_k127_2452813_20 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000002891 173.0
HFD1_k127_2452813_21 - - - - 0.00000000000000000000000000000000000000000003645 171.0
HFD1_k127_2452813_22 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000002933 169.0
HFD1_k127_2452813_23 MarR family transcriptional regulator - - - 0.00000000000000000000000000000000000002834 147.0
HFD1_k127_2452813_24 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000003549 144.0
HFD1_k127_2452813_25 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000594 139.0
HFD1_k127_2452813_26 Protein tyrosine kinase - - - 0.000000000000000000000000001149 129.0
HFD1_k127_2452813_27 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000001373 113.0
HFD1_k127_2452813_28 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000007858 103.0
HFD1_k127_2452813_29 RDD family - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000003097 100.0
HFD1_k127_2452813_3 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 574.0
HFD1_k127_2452813_30 - - - - 0.0000000000000000001055 92.0
HFD1_k127_2452813_32 - - - - 0.0000000000001811 75.0
HFD1_k127_2452813_33 PFAM metallophosphoesterase K07098 - - 0.00000009424 62.0
HFD1_k127_2452813_34 PEGA domain - - - 0.0000344 57.0
HFD1_k127_2452813_4 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 548.0
HFD1_k127_2452813_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 484.0
HFD1_k127_2452813_6 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 482.0
HFD1_k127_2452813_7 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 460.0
HFD1_k127_2452813_8 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 327.0
HFD1_k127_2452813_9 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 305.0
HFD1_k127_2461475_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000352 208.0
HFD1_k127_2461475_1 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000000001224 175.0
HFD1_k127_2473818_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 527.0
HFD1_k127_2484981_0 K02A2.6-like - - - 1.263e-269 916.0
HFD1_k127_2489189_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1253.0
HFD1_k127_2489189_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 6.708e-318 987.0
HFD1_k127_2489189_11 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 313.0
HFD1_k127_2489189_12 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 301.0
HFD1_k127_2489189_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 293.0
HFD1_k127_2489189_14 response regulator, receiver K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 282.0
HFD1_k127_2489189_15 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000005565 243.0
HFD1_k127_2489189_16 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000002554 144.0
HFD1_k127_2489189_17 - - - - 0.00000000000000000000000000002085 124.0
HFD1_k127_2489189_18 Cold shock protein K03704 - - 0.0000000000000000000000004633 105.0
HFD1_k127_2489189_19 ACT domain - - - 0.00000000002797 71.0
HFD1_k127_2489189_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 2.307e-247 776.0
HFD1_k127_2489189_20 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000041 67.0
HFD1_k127_2489189_21 His Kinase A (phosphoacceptor) domain - - - 0.000004239 55.0
HFD1_k127_2489189_3 Amino acid permease - - - 8.869e-236 753.0
HFD1_k127_2489189_4 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 469.0
HFD1_k127_2489189_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 456.0
HFD1_k127_2489189_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 441.0
HFD1_k127_2489189_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 413.0
HFD1_k127_2489189_8 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 415.0
HFD1_k127_2489189_9 protein histidine kinase activity K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 413.0
HFD1_k127_2492420_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 305.0
HFD1_k127_2492420_1 Phage integrase family - - - 0.00003292 49.0
HFD1_k127_2499657_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 8.327e-272 852.0
HFD1_k127_2499657_1 Cysteine-rich domain K00113 - 1.1.5.3 2.91e-209 658.0
HFD1_k127_2499657_10 virulence factor MVIN family protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 476.0
HFD1_k127_2499657_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 447.0
HFD1_k127_2499657_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 435.0
HFD1_k127_2499657_13 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 422.0
HFD1_k127_2499657_14 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 406.0
HFD1_k127_2499657_15 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 372.0
HFD1_k127_2499657_16 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 363.0
HFD1_k127_2499657_17 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 382.0
HFD1_k127_2499657_18 phosphate acetyltransferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 349.0
HFD1_k127_2499657_19 Peptidase dimerisation domain protein K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 346.0
HFD1_k127_2499657_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 9.27e-209 657.0
HFD1_k127_2499657_20 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 312.0
HFD1_k127_2499657_21 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 309.0
HFD1_k127_2499657_22 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 303.0
HFD1_k127_2499657_23 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 293.0
HFD1_k127_2499657_24 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001505 283.0
HFD1_k127_2499657_25 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007626 273.0
HFD1_k127_2499657_26 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001597 264.0
HFD1_k127_2499657_27 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 264.0
HFD1_k127_2499657_28 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006376 254.0
HFD1_k127_2499657_29 mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001302 250.0
HFD1_k127_2499657_3 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 607.0
HFD1_k127_2499657_30 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002708 260.0
HFD1_k127_2499657_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001131 234.0
HFD1_k127_2499657_32 xylan catabolic process K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000003928 230.0
HFD1_k127_2499657_33 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000005301 225.0
HFD1_k127_2499657_34 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000005984 221.0
HFD1_k127_2499657_35 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000001511 240.0
HFD1_k127_2499657_36 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000002638 207.0
HFD1_k127_2499657_37 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000009652 198.0
HFD1_k127_2499657_38 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000001429 192.0
HFD1_k127_2499657_39 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000004504 193.0
HFD1_k127_2499657_4 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 582.0
HFD1_k127_2499657_40 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000001114 181.0
HFD1_k127_2499657_41 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000008221 190.0
HFD1_k127_2499657_42 - - - - 0.00000000000000000000000000000000000000000000003346 171.0
HFD1_k127_2499657_43 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000221 175.0
HFD1_k127_2499657_44 Cupin 2, conserved barrel domain protein K01809,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000006421 154.0
HFD1_k127_2499657_45 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000004746 141.0
HFD1_k127_2499657_46 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000002553 139.0
HFD1_k127_2499657_47 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000002993 143.0
HFD1_k127_2499657_48 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000001837 123.0
HFD1_k127_2499657_49 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000004057 129.0
HFD1_k127_2499657_5 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 606.0
HFD1_k127_2499657_50 domain, Protein - - - 0.00000000000000000000000000503 130.0
HFD1_k127_2499657_51 TIGRFAM TonB K03832 - - 0.000000000000000000000000396 117.0
HFD1_k127_2499657_52 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000004138 124.0
HFD1_k127_2499657_53 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000006392 113.0
HFD1_k127_2499657_54 Belongs to the Fur family K09825 - - 0.000000000000000000000002991 109.0
HFD1_k127_2499657_55 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000001327 106.0
HFD1_k127_2499657_56 Biotin-requiring enzyme - - - 0.000000000000000000001518 103.0
HFD1_k127_2499657_57 Belongs to the UPF0102 family K07460 - - 0.0000000000003773 78.0
HFD1_k127_2499657_58 Sigma-70, region 4 K03088 - - 0.0000000000004376 77.0
HFD1_k127_2499657_59 Protein of unknown function (DUF4230) - - - 0.0000000006353 68.0
HFD1_k127_2499657_6 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 504.0
HFD1_k127_2499657_60 Roadblock/LC7 domain - - - 0.00000000493 62.0
HFD1_k127_2499657_63 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000003778 58.0
HFD1_k127_2499657_64 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000006036 55.0
HFD1_k127_2499657_65 Protein of unknown function (DUF3225) - - - 0.00001508 53.0
HFD1_k127_2499657_66 - - - - 0.0001474 50.0
HFD1_k127_2499657_67 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0003243 52.0
HFD1_k127_2499657_7 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 507.0
HFD1_k127_2499657_8 Lamin Tail Domain K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 520.0
HFD1_k127_2499657_9 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 487.0
HFD1_k127_250209_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 2.295e-235 748.0
HFD1_k127_250209_1 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 567.0
HFD1_k127_250209_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 458.0
HFD1_k127_250209_3 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 398.0
HFD1_k127_250209_4 - - - - 0.0000000000000000000003506 101.0
HFD1_k127_2504518_0 - - - - 0.0000000000000000002331 89.0
HFD1_k127_2504518_3 - - - - 0.0000000003495 62.0
HFD1_k127_2506725_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 312.0
HFD1_k127_2516495_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.133e-224 707.0
HFD1_k127_2516495_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 457.0
HFD1_k127_2516495_10 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003945 235.0
HFD1_k127_2516495_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000007517 220.0
HFD1_k127_2516495_12 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000003135 216.0
HFD1_k127_2516495_13 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000000000005636 186.0
HFD1_k127_2516495_14 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000008313 174.0
HFD1_k127_2516495_15 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000001889 156.0
HFD1_k127_2516495_16 cellular response to heat K09807 - - 0.000000000000000000000000000000000006332 146.0
HFD1_k127_2516495_17 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000946 132.0
HFD1_k127_2516495_18 Glycosyltransferase family 87 K13671 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000001498 70.0
HFD1_k127_2516495_19 NIPSNAP - - - 0.000007976 48.0
HFD1_k127_2516495_2 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 467.0
HFD1_k127_2516495_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 428.0
HFD1_k127_2516495_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 393.0
HFD1_k127_2516495_5 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 392.0
HFD1_k127_2516495_6 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 338.0
HFD1_k127_2516495_7 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 324.0
HFD1_k127_2516495_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000424 284.0
HFD1_k127_2516495_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003717 262.0
HFD1_k127_2517665_0 Protein of unknown function (DUF4256) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 318.0
HFD1_k127_2517665_1 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000003181 221.0
HFD1_k127_2517665_2 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000001623 121.0
HFD1_k127_2523053_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001026 278.0
HFD1_k127_2532489_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1296.0
HFD1_k127_2532489_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009189 570.0
HFD1_k127_2532489_10 - - - - 0.000000000000000000002373 102.0
HFD1_k127_2532489_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 348.0
HFD1_k127_2532489_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 351.0
HFD1_k127_2532489_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 323.0
HFD1_k127_2532489_5 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000947 272.0
HFD1_k127_2532489_6 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004058 259.0
HFD1_k127_2532489_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000009294 246.0
HFD1_k127_2532489_8 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000505 194.0
HFD1_k127_2532489_9 Dna alkylation repair - - - 0.000000000000000000000000000000000000000000000000000114 193.0
HFD1_k127_253289_0 PFAM Integrase catalytic - - - 0.000000000003477 78.0
HFD1_k127_2535658_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 531.0
HFD1_k127_2535658_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 420.0
HFD1_k127_2535658_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000008507 124.0
HFD1_k127_2535658_11 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000001064 112.0
HFD1_k127_2535658_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 292.0
HFD1_k127_2535658_3 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000000000000000000000000000000000000000000000000000002614 240.0
HFD1_k127_2535658_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000002369 164.0
HFD1_k127_2535658_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000004627 142.0
HFD1_k127_2535658_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000008132 138.0
HFD1_k127_2535658_7 transport - - - 0.00000000000000000000000000000000006934 141.0
HFD1_k127_2535658_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000003986 128.0
HFD1_k127_2535658_9 competence protein - - - 0.0000000000000000000000000000007167 132.0
HFD1_k127_2546245_0 queuine tRNA-ribosyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 621.0
HFD1_k127_2547936_0 FtsX-like permease family - - - 1.415e-221 715.0
HFD1_k127_2547936_1 MacB-like periplasmic core domain - - - 2.738e-210 680.0
HFD1_k127_2547936_2 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000228 138.0
HFD1_k127_2547936_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000004164 121.0
HFD1_k127_2547936_5 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.00001374 53.0
HFD1_k127_2547936_6 - - - - 0.00002999 51.0
HFD1_k127_2549822_0 Belongs to the type-B carboxylesterase lipase family - GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - 0.0008996 43.0
HFD1_k127_2576015_0 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000002325 117.0
HFD1_k127_2576015_1 Hep Hag repeat protein - - - 0.00007121 54.0
HFD1_k127_259719_0 Putative glucoamylase K13688 - - 0.0 2735.0
HFD1_k127_259719_1 Carboxyl transferase domain - - - 8.75e-207 655.0
HFD1_k127_259719_10 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000002042 245.0
HFD1_k127_259719_11 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000007457 188.0
HFD1_k127_259719_12 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K16881 GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051748,GO:0055086,GO:0070569,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000523 179.0
HFD1_k127_259719_13 - - - - 0.000000000000000000000000000000000001069 153.0
HFD1_k127_259719_14 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000001118 151.0
HFD1_k127_259719_15 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000746 149.0
HFD1_k127_259719_16 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000000002509 142.0
HFD1_k127_259719_17 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000009757 121.0
HFD1_k127_259719_18 CYTH K05873 - 4.6.1.1 0.00000000000000000000000004498 115.0
HFD1_k127_259719_19 Belongs to the ompA family - - - 0.00000000000000000000007726 110.0
HFD1_k127_259719_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 562.0
HFD1_k127_259719_20 alkyl hydroperoxide reductase - - - 0.00000000000001773 77.0
HFD1_k127_259719_21 Redoxin K03564 - 1.11.1.15 0.0000002518 54.0
HFD1_k127_259719_3 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 487.0
HFD1_k127_259719_4 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 478.0
HFD1_k127_259719_5 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 480.0
HFD1_k127_259719_6 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 469.0
HFD1_k127_259719_7 Aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 364.0
HFD1_k127_259719_8 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 318.0
HFD1_k127_259719_9 Carboxypeptidase regulatory-like domain K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001394 284.0
HFD1_k127_2614211_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 387.0
HFD1_k127_2616515_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0 1180.0
HFD1_k127_2616515_1 Belongs to the malate synthase family K01638 - 2.3.3.9 2.939e-309 957.0
HFD1_k127_2616515_10 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 391.0
HFD1_k127_2616515_11 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 359.0
HFD1_k127_2616515_12 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000005661 242.0
HFD1_k127_2616515_14 - - - - 0.000000000000000000000000000000000000000008061 157.0
HFD1_k127_2616515_15 - - - - 0.00000000000000000000000000000000001239 141.0
HFD1_k127_2616515_16 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000000002408 115.0
HFD1_k127_2616515_17 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000001206 106.0
HFD1_k127_2616515_18 Transcriptional regulatory protein, C terminal - - - 0.0000000000000004951 93.0
HFD1_k127_2616515_19 Transcriptional regulatory protein, C terminal - - - 0.000000000000000638 93.0
HFD1_k127_2616515_2 Belongs to the carbamoyltransferase HypF family K04656 - - 1.511e-305 957.0
HFD1_k127_2616515_3 dna ligase - - - 1.084e-232 726.0
HFD1_k127_2616515_4 hydrogenase expression formation protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 593.0
HFD1_k127_2616515_5 ATP dependent DNA ligase C terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 558.0
HFD1_k127_2616515_6 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 539.0
HFD1_k127_2616515_7 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 494.0
HFD1_k127_2616515_8 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 519.0
HFD1_k127_2616515_9 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 416.0
HFD1_k127_2617090_0 - - - - 0.00001972 57.0
HFD1_k127_2617090_1 Tetratricopeptide repeat - - - 0.0001059 54.0
HFD1_k127_2627189_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 393.0
HFD1_k127_2627189_1 Fibronectin type 3 domain - - - 0.00000000000008218 86.0
HFD1_k127_2627189_2 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000009388 63.0
HFD1_k127_2633928_0 ThiC-associated domain K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 8.657e-314 971.0
HFD1_k127_2647571_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009092 246.0
HFD1_k127_2647571_1 - - - - 0.0000000000000000000000000000000000000000001979 161.0
HFD1_k127_2647571_11 - - - - 0.00000000000000005168 80.0
HFD1_k127_2647571_13 - - - - 0.000000000000002088 76.0
HFD1_k127_2647571_14 - - - - 0.0000000000003336 70.0
HFD1_k127_2647571_15 - - - - 0.000000000001284 71.0
HFD1_k127_2647571_16 mitotic sister chromatid biorientation - - - 0.000000000006262 66.0
HFD1_k127_2647571_17 - - - - 0.0000000000651 62.0
HFD1_k127_2647571_18 - - - - 0.000000001774 59.0
HFD1_k127_2647571_2 - - - - 0.000000000000000000000000000002154 120.0
HFD1_k127_2647571_22 protein Sb1514s002020 source - - - 0.0000003592 53.0
HFD1_k127_2647571_23 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000003845 56.0
HFD1_k127_2647571_24 - - - - 0.0000005871 56.0
HFD1_k127_2647571_25 - - - - 0.0000007086 54.0
HFD1_k127_2647571_26 - - - - 0.000000803 51.0
HFD1_k127_2647571_27 mitotic sister chromatid biorientation - - - 0.000006013 48.0
HFD1_k127_2647571_28 - - - - 0.000006792 48.0
HFD1_k127_2647571_3 - - - - 0.000000000000000000000000000005864 119.0
HFD1_k127_2647571_4 - - - - 0.0000000000000000000000002591 107.0
HFD1_k127_2647571_6 - - - - 0.000000000000000000004961 98.0
HFD1_k127_2647571_7 - - - - 0.00000000000000000002845 92.0
HFD1_k127_2647571_8 - - - - 0.0000000000000000003916 87.0
HFD1_k127_2647571_9 peptide cross-linking - - - 0.000000000000000002392 84.0
HFD1_k127_2650969_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986,K15342 - 2.7.7.49 8.482e-198 624.0
HFD1_k127_2653959_0 - - - - 0.000000000000000000000000000000000001249 151.0
HFD1_k127_2653959_1 Rubrerythrin - - - 0.00000000000000000000002488 101.0
HFD1_k127_2673298_0 reverse transcriptase - - - 3.227e-198 660.0
HFD1_k127_2678604_0 - - - - 7.608e-243 760.0
HFD1_k127_2678604_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000009043 207.0
HFD1_k127_2678604_2 Phage portal protein, lambda family - - - 0.000000000000000000000000000000000296 134.0
HFD1_k127_2685579_0 glutamate-cysteine ligase activity K06048 GO:0003674,GO:0003824,GO:0016874,GO:0016879 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
HFD1_k127_2685579_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 338.0
HFD1_k127_2686422_0 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 384.0
HFD1_k127_2686422_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 294.0
HFD1_k127_2686422_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443,K16786,K16787 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000001846 230.0
HFD1_k127_2686422_3 cell redox homeostasis K02199 - - 0.0000000000000000000000000004797 120.0
HFD1_k127_2686422_4 Pfam:N_methyl_2 - - - 0.0000000000000000004063 94.0
HFD1_k127_2686422_5 Pfam:N_methyl_2 K02650 - - 0.0002405 44.0
HFD1_k127_2686422_6 Ring finger domain K10635 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008285,GO:0009056,GO:0009057,GO:0009791,GO:0009908,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0022414,GO:0030163,GO:0031624,GO:0032446,GO:0032501,GO:0032502,GO:0036211,GO:0040008,GO:0042127,GO:0043161,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044390,GO:0045926,GO:0046620,GO:0046621,GO:0048367,GO:0048437,GO:0048518,GO:0048519,GO:0048523,GO:0048608,GO:0048638,GO:0048640,GO:0048731,GO:0048831,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051094,GO:0051239,GO:0051240,GO:0051241,GO:0051603,GO:0051865,GO:0061458,GO:0061630,GO:0061659,GO:0065007,GO:0070647,GO:0071704,GO:0090567,GO:0099402,GO:0140096,GO:1900055,GO:1900057,GO:1901564,GO:1901565,GO:1901575,GO:1905623,GO:2000024,GO:2000026 2.3.2.27 0.0003516 49.0
HFD1_k127_2694142_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000877 44.0
HFD1_k127_27092_0 self proteolysis K11021 - - 0.0000000000000000000000000000000000000000000000000000000000001921 244.0
HFD1_k127_27092_1 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000001433 221.0
HFD1_k127_27092_2 TraM recognition site of TraD and TraG K03205 - - 0.00000000000002793 87.0
HFD1_k127_27092_3 - - - - 0.000001582 49.0
HFD1_k127_27092_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000729 44.0
HFD1_k127_2715418_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1163.0
HFD1_k127_2715418_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1045.0
HFD1_k127_2715418_10 His Kinase A (phosphoacceptor) domain K03320 - - 0.00000000000000000003619 95.0
HFD1_k127_2715418_13 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000003721 52.0
HFD1_k127_2715418_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 544.0
HFD1_k127_2715418_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 384.0
HFD1_k127_2715418_4 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004479 284.0
HFD1_k127_2715418_5 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000003184 232.0
HFD1_k127_2715418_6 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000208 171.0
HFD1_k127_2715418_7 Tetratricopeptide repeat - - - 0.0000000000000000000000002321 120.0
HFD1_k127_2715418_8 - - - - 0.0000000000000000000001412 104.0
HFD1_k127_2715418_9 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.00000000000000000001033 96.0
HFD1_k127_2716000_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 604.0
HFD1_k127_2716000_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 312.0
HFD1_k127_2716000_2 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001119 241.0
HFD1_k127_2716000_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000005094 115.0
HFD1_k127_2716000_4 typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.000007814 57.0
HFD1_k127_2717012_0 protein kinase activity - - - 1.233e-195 642.0
HFD1_k127_2717012_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 433.0
HFD1_k127_2717012_2 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007547 293.0
HFD1_k127_2717012_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000005098 216.0
HFD1_k127_2717012_4 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000001087 190.0
HFD1_k127_2722886_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000227 85.0
HFD1_k127_2722886_1 cAMP biosynthetic process K03641 - - 0.00001102 52.0
HFD1_k127_2730324_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1416.0
HFD1_k127_2730324_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.536e-262 821.0
HFD1_k127_2730324_10 Uncharacterized conserved protein (COG2071) - - - 0.0000000001056 71.0
HFD1_k127_2730324_12 cell adhesion involved in biofilm formation - - - 0.000119 49.0
HFD1_k127_2730324_2 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 359.0
HFD1_k127_2730324_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000003119 200.0
HFD1_k127_2730324_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000007464 215.0
HFD1_k127_2730324_5 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000007442 176.0
HFD1_k127_2730324_6 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000001314 153.0
HFD1_k127_2730324_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000001632 127.0
HFD1_k127_2730324_8 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.000000000000000000000000000007223 132.0
HFD1_k127_2730324_9 Pkd domain containing protein - - - 0.0000000000000000000000000006877 126.0
HFD1_k127_274173_0 reverse transcriptase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 544.0
HFD1_k127_274173_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 341.0
HFD1_k127_274173_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000004935 183.0
HFD1_k127_2750502_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 346.0
HFD1_k127_2762621_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 508.0
HFD1_k127_2762621_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 351.0
HFD1_k127_2762621_2 transcriptional regulator K21900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 307.0
HFD1_k127_2762621_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000001909 233.0
HFD1_k127_2762621_4 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000000005258 87.0
HFD1_k127_2762621_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0002177 44.0
HFD1_k127_2781650_0 Transposase - - - 1.021e-208 663.0
HFD1_k127_2783120_0 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000003125 183.0
HFD1_k127_2783120_1 alpha-ribazole phosphatase activity - - - 0.0000000000000000001125 91.0
HFD1_k127_2783120_2 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.00000000000000003361 83.0
HFD1_k127_2820320_0 - - - - 0.00000000000000000000000000000000000000251 146.0
HFD1_k127_2820320_1 - - - - 0.0000000000000000001176 89.0
HFD1_k127_2820320_2 - - - - 0.0000000000000000001603 88.0
HFD1_k127_2820320_6 - - - - 0.0000000000003951 71.0
HFD1_k127_2820320_8 - - - - 0.00000002137 56.0
HFD1_k127_2828344_0 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 420.0
HFD1_k127_2828344_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000001928 177.0
HFD1_k127_283981_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 587.0
HFD1_k127_283981_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 461.0
HFD1_k127_283981_2 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 456.0
HFD1_k127_283981_3 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001936 291.0
HFD1_k127_283981_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000001026 191.0
HFD1_k127_283981_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.0000000000000000000000000000001012 138.0
HFD1_k127_283981_6 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000202 119.0
HFD1_k127_283981_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000005734 71.0
HFD1_k127_2842296_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 284.0
HFD1_k127_2842296_1 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002565 260.0
HFD1_k127_2842296_2 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000000003013 91.0
HFD1_k127_2908017_0 IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 568.0
HFD1_k127_2908017_1 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000000000003524 165.0
HFD1_k127_2914848_0 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 417.0
HFD1_k127_2914848_1 PFAM HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000004632 147.0
HFD1_k127_2914848_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000006776 130.0
HFD1_k127_2914848_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000002662 68.0
HFD1_k127_2926912_0 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 4.347e-266 832.0
HFD1_k127_2926912_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 574.0
HFD1_k127_2926912_10 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 316.0
HFD1_k127_2926912_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002348 269.0
HFD1_k127_2926912_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000004731 243.0
HFD1_k127_2926912_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000002779 241.0
HFD1_k127_2926912_14 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000005867 246.0
HFD1_k127_2926912_15 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000002384 244.0
HFD1_k127_2926912_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000002556 221.0
HFD1_k127_2926912_17 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000000002654 234.0
HFD1_k127_2926912_18 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000005006 186.0
HFD1_k127_2926912_19 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000005969 166.0
HFD1_k127_2926912_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 503.0
HFD1_k127_2926912_20 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000001281 169.0
HFD1_k127_2926912_21 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000001367 136.0
HFD1_k127_2926912_22 - - - - 0.00000000000000000000000000001527 128.0
HFD1_k127_2926912_23 Thioredoxin-like - - - 0.00000000000000000000000000002392 135.0
HFD1_k127_2926912_24 - - - - 0.00000000000000000000000002524 115.0
HFD1_k127_2926912_25 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000002926 116.0
HFD1_k127_2926912_26 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000121 109.0
HFD1_k127_2926912_27 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000005288 111.0
HFD1_k127_2926912_28 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000002641 103.0
HFD1_k127_2926912_29 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000311 105.0
HFD1_k127_2926912_3 Mur ligase middle domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 463.0
HFD1_k127_2926912_30 XdhC and CoxI family K07402 - - 0.000000000000000000001072 98.0
HFD1_k127_2926912_31 Rhomboid family - - - 0.00000000000000007054 94.0
HFD1_k127_2926912_32 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000004865 91.0
HFD1_k127_2926912_33 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000007703 81.0
HFD1_k127_2926912_34 Universal stress protein family - - - 0.0000000000002313 81.0
HFD1_k127_2926912_35 ABC-type multidrug transport system ATPase component - - - 0.0000000000003385 84.0
HFD1_k127_2926912_36 PFAM S-layer domain protein - - - 0.000000000001984 80.0
HFD1_k127_2926912_37 Protein of unknown function (DUF3616) - - - 0.00000002104 68.0
HFD1_k127_2926912_38 hydroxyisourate hydrolase activity - - - 0.0000003431 52.0
HFD1_k127_2926912_4 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 416.0
HFD1_k127_2926912_40 Belongs to the peptidase M10A family K01388,K01394,K01396,K01402,K01413,K07763,K07994,K07999 GO:0000122,GO:0001047,GO:0001067,GO:0001666,GO:0001817,GO:0001819,GO:0001959,GO:0001960,GO:0001961,GO:0002009,GO:0002011,GO:0002682,GO:0002683,GO:0002684,GO:0002697,GO:0002791,GO:0002793,GO:0002831,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005509,GO:0005518,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006355,GO:0006357,GO:0006508,GO:0006606,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006928,GO:0006950,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0008284,GO:0009056,GO:0009605,GO:0009607,GO:0009611,GO:0009615,GO:0009628,GO:0009653,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0014070,GO:0015031,GO:0015833,GO:0016043,GO:0016477,GO:0016787,GO:0017038,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0022411,GO:0022617,GO:0023051,GO:0023056,GO:0023057,GO:0030198,GO:0030334,GO:0030574,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031348,GO:0031349,GO:0032101,GO:0032479,GO:0032481,GO:0032502,GO:0032647,GO:0032727,GO:0032879,GO:0032880,GO:0032963,GO:0033036,GO:0033365,GO:0034504,GO:0034613,GO:0035313,GO:0036293,GO:0040011,GO:0040012,GO:0042060,GO:0042127,GO:0042221,GO:0042493,GO:0042886,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0043900,GO:0044212,GO:0044238,GO:0044319,GO:0044421,GO:0044424,GO:0044464,GO:0044877,GO:0045088,GO:0045089,GO:0045184,GO:0045824,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046872,GO:0046907,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048729,GO:0048856,GO:0048870,GO:0050678,GO:0050679,GO:0050688,GO:0050691,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0060054,GO:0060255,GO:0060338,GO:0060339,GO:0060340,GO:0060429,GO:0060759,GO:0060760,GO:0060761,GO:0065007,GO:0070011,GO:0070201,GO:0070482,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0080090,GO:0080134,GO:0090087,GO:0090504,GO:0090505,GO:0097159,GO:0098586,GO:0140096,GO:1901163,GO:1901363,GO:1901564,GO:1902679,GO:1902680,GO:1902739,GO:1902741,GO:1903506,GO:1903507,GO:1903508,GO:1903530,GO:1903532,GO:1904951,GO:2000026,GO:2000112,GO:2000113,GO:2000145,GO:2000241,GO:2001141 3.4.24.17,3.4.24.22,3.4.24.34,3.4.24.65,3.4.24.7,3.4.24.80 0.000002845 60.0
HFD1_k127_2926912_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 338.0
HFD1_k127_2926912_6 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 332.0
HFD1_k127_2926912_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 322.0
HFD1_k127_2926912_8 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 331.0
HFD1_k127_2926912_9 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 315.0
HFD1_k127_2960142_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001021 275.0
HFD1_k127_2966209_0 PFAM Transposase IS66 family K07484 - - 0.00000000000000000000000000000000000000000000000000000000000003025 232.0
HFD1_k127_2985683_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 8.952e-266 849.0
HFD1_k127_2985683_1 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 392.0
HFD1_k127_2985683_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000001149 50.0
HFD1_k127_301678_0 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000964 233.0
HFD1_k127_301678_1 Transposase DDE domain - - - 0.000000000000000000000000000000004035 133.0
HFD1_k127_302762_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005682 288.0
HFD1_k127_3083421_0 choline dehydrogenase activity - - - 2.768e-306 947.0
HFD1_k127_3083421_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.811e-223 713.0
HFD1_k127_3083421_10 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000004239 55.0
HFD1_k127_3083421_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 7.376e-219 702.0
HFD1_k127_3083421_3 Aldehyde dehydrogenase K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 416.0
HFD1_k127_3083421_4 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 385.0
HFD1_k127_3083421_5 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 330.0
HFD1_k127_3083421_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004088 259.0
HFD1_k127_3083421_7 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000003472 226.0
HFD1_k127_3083421_9 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002145 126.0
HFD1_k127_3086138_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 574.0
HFD1_k127_3086138_1 domain protein - - - 0.00000000000000000002377 101.0
HFD1_k127_3086138_2 PFAM Tetratricopeptide repeat - - - 0.0000001156 63.0
HFD1_k127_3086138_3 peptidyl-tyrosine sulfation - - - 0.00002533 56.0
HFD1_k127_309769_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000004107 133.0
HFD1_k127_309769_1 HNH endonuclease - - - 0.000000000000000000001788 104.0
HFD1_k127_309769_3 Ead/Ea22-like protein - - - 0.00000000000001351 79.0
HFD1_k127_3103907_0 Transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 314.0
HFD1_k127_3139697_0 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000002694 95.0
HFD1_k127_3166039_0 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000001391 199.0
HFD1_k127_316782_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 597.0
HFD1_k127_3191274_0 transposase - - - 0.000000000000000000000000000000000000000000000000000000004085 205.0
HFD1_k127_3191274_1 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.000000000000000000000000000000000002546 138.0
HFD1_k127_3191274_2 sequence-specific DNA binding - - - 0.000000000000000000001191 98.0
HFD1_k127_319264_0 Zinc-binding dehydrogenase - - - 6.356e-214 691.0
HFD1_k127_319264_1 Highly conserved protein containing a thioredoxin domain K20948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 325.0
HFD1_k127_319264_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000861 184.0
HFD1_k127_319264_3 metallopeptidase activity - - - 0.0000000000000000000000000001313 124.0
HFD1_k127_319264_4 Disulphide bond corrector protein DsbC - - - 0.000000000000000000006852 99.0
HFD1_k127_319264_5 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000006704 49.0
HFD1_k127_3233950_0 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000002983 184.0
HFD1_k127_3233950_1 Peptidase family C25 - - - 0.0000000000000000000000000001717 135.0
HFD1_k127_3233950_2 Belongs to the peptidase S8 family - - - 0.000000000000009502 90.0
HFD1_k127_3233950_3 Uncharacterised nucleotidyltransferase - - - 0.00000008756 64.0
HFD1_k127_3236033_0 Fibronectin type III-like domain K05349 - 3.2.1.21 5e-324 1015.0
HFD1_k127_3236033_1 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 1.527e-282 874.0
HFD1_k127_3236033_2 Putative esterase K07214 - - 3.722e-210 658.0
HFD1_k127_3236033_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 416.0
HFD1_k127_3236033_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000002838 240.0
HFD1_k127_3236033_5 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000003389 186.0
HFD1_k127_3236033_6 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000006079 100.0
HFD1_k127_3236033_7 Alpha-L-fucosidase C-terminal domain K01206 - 3.2.1.51 0.000000000000002137 81.0
HFD1_k127_3236033_8 belongs to the aldehyde dehydrogenase family K13877,K14519 - 1.2.1.26,1.2.1.4 0.00000000000002944 73.0
HFD1_k127_3236033_9 - - - - 0.00005235 51.0
HFD1_k127_3240301_0 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000618 132.0
HFD1_k127_3240301_1 polysaccharide biosynthetic process K06409 - - 0.0000002076 56.0
HFD1_k127_3241919_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1316.0
HFD1_k127_3241919_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1202.0
HFD1_k127_3241919_10 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000001805 234.0
HFD1_k127_3241919_11 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000002839 194.0
HFD1_k127_3241919_12 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000001303 160.0
HFD1_k127_3241919_13 GGDEF domain - - - 0.000000000000000000000000000000000000000005146 167.0
HFD1_k127_3241919_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000003502 156.0
HFD1_k127_3241919_15 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000000006034 150.0
HFD1_k127_3241919_16 PFAM homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000531 147.0
HFD1_k127_3241919_17 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000000000000000000000000004828 145.0
HFD1_k127_3241919_18 cheY-homologous receiver domain - - - 0.000000000000000000000000000000009038 146.0
HFD1_k127_3241919_19 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000001123 108.0
HFD1_k127_3241919_2 valine-tRNA ligase activity K01873 GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 1.059e-314 986.0
HFD1_k127_3241919_20 response regulator, receiver - - - 0.00000000000000000000004649 103.0
HFD1_k127_3241919_21 Putative NAD(P)-binding K03499 - - 0.000000000000000000001353 108.0
HFD1_k127_3241919_22 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000001922 109.0
HFD1_k127_3241919_23 - - - - 0.000000000000001313 83.0
HFD1_k127_3241919_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 557.0
HFD1_k127_3241919_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 532.0
HFD1_k127_3241919_5 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 525.0
HFD1_k127_3241919_6 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 515.0
HFD1_k127_3241919_7 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 413.0
HFD1_k127_3241919_8 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 291.0
HFD1_k127_3241919_9 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005692 254.0
HFD1_k127_3245281_0 - - - - 0.00000000000000000000000008415 109.0
HFD1_k127_3245281_1 - - - - 0.000000000000003802 76.0
HFD1_k127_3245281_2 - - - - 0.0000000000466 65.0
HFD1_k127_3245281_3 - - - - 0.000000003717 58.0
HFD1_k127_3251572_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 489.0
HFD1_k127_3251572_1 Transposase - - - 0.0000000000000000000000000000000000000000459 153.0
HFD1_k127_3262164_0 Ankyrin repeats (many copies) - - - 1.333e-209 675.0
HFD1_k127_3262164_1 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 546.0
HFD1_k127_3262164_10 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002489 239.0
HFD1_k127_3262164_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000007206 183.0
HFD1_k127_3262164_12 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001566 184.0
HFD1_k127_3262164_13 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000003048 158.0
HFD1_k127_3262164_14 Yqey-like protein K09117 - - 0.000000000000000000000000000000000002367 143.0
HFD1_k127_3262164_15 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000006878 150.0
HFD1_k127_3262164_16 - - - - 0.000000000000000000000000000000007397 146.0
HFD1_k127_3262164_17 - - - - 0.000000000000000000000000001332 122.0
HFD1_k127_3262164_18 Tyrosine phosphatase family - - - 0.000000000000000000000004869 109.0
HFD1_k127_3262164_19 PFAM membrane-flanked domain - - - 0.00000001406 63.0
HFD1_k127_3262164_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 515.0
HFD1_k127_3262164_20 - - - - 0.0000003161 54.0
HFD1_k127_3262164_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 473.0
HFD1_k127_3262164_4 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 452.0
HFD1_k127_3262164_5 Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
HFD1_k127_3262164_6 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 375.0
HFD1_k127_3262164_7 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 321.0
HFD1_k127_3262164_8 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 296.0
HFD1_k127_3262164_9 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 292.0
HFD1_k127_3274183_0 Heat shock 70 kDa protein K04043 - - 2.489e-232 735.0
HFD1_k127_3274183_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 598.0
HFD1_k127_3274183_10 COG0438 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002118 280.0
HFD1_k127_3274183_11 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003872 271.0
HFD1_k127_3274183_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000000000007798 136.0
HFD1_k127_3274183_13 iron-sulfur cluster assembly K07400 - - 0.00000000000000000000000000000001559 134.0
HFD1_k127_3274183_15 Response regulator, receiver - - - 0.0000002338 61.0
HFD1_k127_3274183_16 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00001323 47.0
HFD1_k127_3274183_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00001868 55.0
HFD1_k127_3274183_18 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0003546 51.0
HFD1_k127_3274183_2 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 519.0
HFD1_k127_3274183_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 520.0
HFD1_k127_3274183_4 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 496.0
HFD1_k127_3274183_5 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 461.0
HFD1_k127_3274183_6 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 457.0
HFD1_k127_3274183_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 402.0
HFD1_k127_3274183_8 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 386.0
HFD1_k127_3274183_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 319.0
HFD1_k127_3279339_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000002086 89.0
HFD1_k127_3279339_2 Multicopper oxidase K22348 - 1.16.3.3 0.00001336 48.0
HFD1_k127_3279879_0 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002141 265.0
HFD1_k127_3279879_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000001429 211.0
HFD1_k127_3279879_2 helix_turn_helix, Lux Regulon - - - 0.000003269 57.0
HFD1_k127_3280749_0 Transposase - - - 0.000000000000000000000000000000000000000005579 169.0
HFD1_k127_3282299_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 396.0
HFD1_k127_3282299_1 Probable transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 330.0
HFD1_k127_3284298_0 Domain of unknown function (DUF5117) - - - 0.0 1021.0
HFD1_k127_3284298_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.554e-266 841.0
HFD1_k127_3284298_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 317.0
HFD1_k127_3284298_11 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 294.0
HFD1_k127_3284298_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006211 251.0
HFD1_k127_3284298_13 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000258 221.0
HFD1_k127_3284298_14 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000009305 195.0
HFD1_k127_3284298_15 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000007447 174.0
HFD1_k127_3284298_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000002703 171.0
HFD1_k127_3284298_17 COGs COG4636 conserved - - - 0.00000000000000000000000000000000000000000006932 166.0
HFD1_k127_3284298_18 spore germination - - - 0.00000000000000000000000000000000000000176 151.0
HFD1_k127_3284298_19 membrane K08978 - - 0.000000000000000000000000000004316 123.0
HFD1_k127_3284298_2 SMART Elongator protein 3 MiaB NifB - - - 3.793e-223 700.0
HFD1_k127_3284298_20 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000001382 128.0
HFD1_k127_3284298_21 GDP-mannose mannosyl hydrolase activity K00974,K03574,K18445 - 2.7.7.72,3.6.1.55,3.6.1.61 0.0000000000000000000000000001784 119.0
HFD1_k127_3284298_22 - - - - 0.000000000000000000000000001936 125.0
HFD1_k127_3284298_23 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000584 102.0
HFD1_k127_3284298_24 Modulates RecA activity K03565 - - 0.0000000656 61.0
HFD1_k127_3284298_25 - - - - 0.000001495 49.0
HFD1_k127_3284298_26 Circadian clock protein KaiC - - - 0.00008131 55.0
HFD1_k127_3284298_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 548.0
HFD1_k127_3284298_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 499.0
HFD1_k127_3284298_5 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 418.0
HFD1_k127_3284298_6 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 393.0
HFD1_k127_3284298_7 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 363.0
HFD1_k127_3284298_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 336.0
HFD1_k127_3284298_9 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 338.0
HFD1_k127_3297395_0 DinB family - - - 0.000000001065 66.0
HFD1_k127_3323939_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 392.0
HFD1_k127_3323939_1 Carboxypeptidase regulatory-like domain - - - 0.00000000001525 69.0
HFD1_k127_3323939_2 Helix-turn-helix domain, rpiR family K15835 GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000009937 65.0
HFD1_k127_3326236_0 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000001431 192.0
HFD1_k127_3326236_1 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000000000000000000004796 138.0
HFD1_k127_3326236_3 - - - - 0.00000000006121 64.0
HFD1_k127_3326236_4 COG NOG14600 non supervised orthologous group - - - 0.000006704 49.0
HFD1_k127_3354523_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 456.0
HFD1_k127_3354523_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 407.0
HFD1_k127_3354523_10 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.000000000000000003852 86.0
HFD1_k127_3354523_2 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 306.0
HFD1_k127_3354523_3 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001421 263.0
HFD1_k127_3354523_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 261.0
HFD1_k127_3354523_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000003971 240.0
HFD1_k127_3354523_6 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000001448 231.0
HFD1_k127_3354523_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000009592 225.0
HFD1_k127_3354523_8 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000002468 205.0
HFD1_k127_3354523_9 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000005338 174.0
HFD1_k127_3360752_0 Ribonuclease H protein - - - 0.00000000000000000000000007913 113.0
HFD1_k127_3372088_0 serine-type peptidase activity K01278 - 3.4.14.5 5.481e-207 667.0
HFD1_k127_3372088_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 357.0
HFD1_k127_3372088_10 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000001269 61.0
HFD1_k127_3372088_11 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000001715 61.0
HFD1_k127_3372088_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003952 269.0
HFD1_k127_3372088_3 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001544 265.0
HFD1_k127_3372088_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000003761 258.0
HFD1_k127_3372088_5 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000001072 196.0
HFD1_k127_3372088_6 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000171 160.0
HFD1_k127_3372088_7 Rubrerythrin - - - 0.00000000000000000000000000000000000003757 149.0
HFD1_k127_3372088_8 PFAM Peptidase S53, propeptide - - - 0.000000000000000000000002272 123.0
HFD1_k127_3372088_9 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000001217 62.0
HFD1_k127_337411_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1382.0
HFD1_k127_337411_1 Putative glucoamylase - - - 9.288e-246 763.0
HFD1_k127_337411_10 Ankyrin repeats (many copies) K06015,K06867,K06886 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 376.0
HFD1_k127_337411_11 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 332.0
HFD1_k127_337411_12 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000001109 190.0
HFD1_k127_337411_13 Low affinity iron permease - - - 0.000000000000000000000000000000000000000000000005821 177.0
HFD1_k127_337411_14 Cupin domain - - - 0.000000000000000000000000000000000000000000000006142 174.0
HFD1_k127_337411_15 acetyltransferase - - - 0.00000000000000000000000000000000000000000000002472 175.0
HFD1_k127_337411_16 - - - - 0.00000000000000000000000000000000000000000001499 168.0
HFD1_k127_337411_17 Peptidoglycan-binding domain 1 protein K03286,K12543 - - 0.00000000000000000000000000000001715 138.0
HFD1_k127_337411_18 - - - - 0.00000000000000000000000000000006431 132.0
HFD1_k127_337411_19 - - - - 0.0000000000000000000000000001097 121.0
HFD1_k127_337411_2 Putative glucoamylase - - - 1.652e-201 635.0
HFD1_k127_337411_20 Tyrosine phosphatase family - - - 0.000000000000000000000000009126 118.0
HFD1_k127_337411_21 Transcriptional regulatory protein, C terminal - - - 0.000000000000000007776 99.0
HFD1_k127_337411_22 Beta-xylosidase K01198 - 3.2.1.37 0.00000000000000002815 83.0
HFD1_k127_337411_25 Zinc metalloprotease (Elastase) - - - 0.000000000002939 81.0
HFD1_k127_337411_26 Belongs to the UPF0337 (CsbD) family - - - 0.00003034 49.0
HFD1_k127_337411_3 Holliday junction DNA helicase ruvB N-terminus - - - 9.055e-200 646.0
HFD1_k127_337411_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 610.0
HFD1_k127_337411_5 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 523.0
HFD1_k127_337411_6 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 520.0
HFD1_k127_337411_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 467.0
HFD1_k127_337411_8 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 439.0
HFD1_k127_337411_9 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 370.0
HFD1_k127_3374442_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 1.624e-220 692.0
HFD1_k127_3374442_1 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.933e-215 686.0
HFD1_k127_3374442_10 - - - - 0.00000000000000000000000000000000000000000000000000000000002676 225.0
HFD1_k127_3374442_11 PFAM Major Facilitator Superfamily K08196,K08369 - - 0.0000000000000000000000000000000000000000000000000000000001065 210.0
HFD1_k127_3374442_12 DoxX - - - 0.0000000000000000000000000000000000000005559 152.0
HFD1_k127_3374442_13 OsmC-like protein - - - 0.000000000000000000000000000000000002872 145.0
HFD1_k127_3374442_14 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000002291 136.0
HFD1_k127_3374442_15 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000000000006459 84.0
HFD1_k127_3374442_16 -Thioesterase K01075 - 3.1.2.23 0.000000000006934 72.0
HFD1_k127_3374442_2 NADH oxidase - - - 1.556e-208 658.0
HFD1_k127_3374442_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 431.0
HFD1_k127_3374442_4 PFAM Transketolase central region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 430.0
HFD1_k127_3374442_5 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 400.0
HFD1_k127_3374442_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 379.0
HFD1_k127_3374442_7 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 378.0
HFD1_k127_3374442_8 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 378.0
HFD1_k127_3374442_9 Dehydrogenase E1 component K00161,K00166,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000003906 245.0
HFD1_k127_3389270_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 8.246e-226 713.0
HFD1_k127_3389270_1 FAD binding domain K07077 - - 3.531e-205 651.0
HFD1_k127_3389270_2 Dehydrogenase K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 5.588e-197 638.0
HFD1_k127_3389270_3 COG0208 Ribonucleotide reductase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 490.0
HFD1_k127_3389270_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 431.0
HFD1_k127_3389270_5 YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 373.0
HFD1_k127_3389270_6 Sir2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 325.0
HFD1_k127_3389270_7 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 308.0
HFD1_k127_3389270_8 Cytochrome c554 and c-prime K03620 - - 0.00000000000002183 82.0
HFD1_k127_3389270_9 efflux transmembrane transporter activity - - - 0.000001686 51.0
HFD1_k127_3391704_0 Putative ATPase subunit of terminase (gpP-like) - - - 0.000000000000000000000000000004233 123.0
HFD1_k127_3391704_1 PFAM IS1 transposase K07480 - - 0.000000000000000000000000000007313 123.0
HFD1_k127_3391704_2 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.0000000000000000000005576 97.0
HFD1_k127_3403814_0 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000009448 85.0
HFD1_k127_3414138_0 Cytochrome c - - - 0.0 1090.0
HFD1_k127_3414138_1 Vault protein inter-alpha-trypsin domain K07114 - - 5.831e-194 634.0
HFD1_k127_3414138_10 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 312.0
HFD1_k127_3414138_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
HFD1_k127_3414138_12 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
HFD1_k127_3414138_13 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000003095 247.0
HFD1_k127_3414138_14 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000005213 242.0
HFD1_k127_3414138_15 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001024 238.0
HFD1_k127_3414138_16 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000001532 245.0
HFD1_k127_3414138_17 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000000000000000000000000000001373 230.0
HFD1_k127_3414138_18 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000003832 212.0
HFD1_k127_3414138_19 - K19693 - - 0.000000000000000000000000000000000000000000000000000001931 215.0
HFD1_k127_3414138_2 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 621.0
HFD1_k127_3414138_20 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000000111 194.0
HFD1_k127_3414138_21 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000001484 187.0
HFD1_k127_3414138_22 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000002407 184.0
HFD1_k127_3414138_23 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000232 197.0
HFD1_k127_3414138_24 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000383 182.0
HFD1_k127_3414138_25 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.00000000000000000000000000000000000000000000007072 171.0
HFD1_k127_3414138_26 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000000004221 147.0
HFD1_k127_3414138_27 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000002445 150.0
HFD1_k127_3414138_28 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000002836 106.0
HFD1_k127_3414138_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 612.0
HFD1_k127_3414138_31 Yip1 domain - - - 0.00000000000000007492 91.0
HFD1_k127_3414138_32 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000001521 71.0
HFD1_k127_3414138_33 COG3209 Rhs family protein - - - 0.0000000004067 69.0
HFD1_k127_3414138_4 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 579.0
HFD1_k127_3414138_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 455.0
HFD1_k127_3414138_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 448.0
HFD1_k127_3414138_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 476.0
HFD1_k127_3414138_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 363.0
HFD1_k127_3414138_9 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 347.0
HFD1_k127_3416238_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000001857 207.0
HFD1_k127_3416238_1 DDE superfamily endonuclease - - - 0.00000000000001932 78.0
HFD1_k127_34336_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009494 370.0
HFD1_k127_34336_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 313.0
HFD1_k127_34336_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000475 185.0
HFD1_k127_34336_3 cAMP biosynthetic process - - - 0.0000000000000000000000007215 110.0
HFD1_k127_34336_4 MacB-like periplasmic core domain - - - 0.0000000000000006068 82.0
HFD1_k127_3446762_0 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 471.0
HFD1_k127_3446762_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000002646 187.0
HFD1_k127_3446762_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000003407 165.0
HFD1_k127_3467415_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 593.0
HFD1_k127_3483078_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.161e-219 697.0
HFD1_k127_3483078_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 484.0
HFD1_k127_3483078_10 Dihydrodipicolinate synthase N-acetylneuraminate lyase K01714 - 4.3.3.7 0.00006231 55.0
HFD1_k127_3483078_2 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 480.0
HFD1_k127_3483078_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002003 275.0
HFD1_k127_3483078_4 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002847 291.0
HFD1_k127_3483078_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000002905 184.0
HFD1_k127_3483078_6 PFAM OsmC family protein K07397 - - 0.0000000000000000000000000000006636 127.0
HFD1_k127_3483078_7 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000003155 102.0
HFD1_k127_3483078_8 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000006856 66.0
HFD1_k127_3483078_9 DNA-binding transcriptional activator of the SARP family - - - 0.0000006803 62.0
HFD1_k127_3484567_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.268e-316 989.0
HFD1_k127_3484567_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.116e-297 931.0
HFD1_k127_3484567_10 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 477.0
HFD1_k127_3484567_11 PhoPQ-activated pathogenicity-related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 485.0
HFD1_k127_3484567_12 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 431.0
HFD1_k127_3484567_13 Alkyl sulfatase dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 436.0
HFD1_k127_3484567_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 399.0
HFD1_k127_3484567_15 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 393.0
HFD1_k127_3484567_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 372.0
HFD1_k127_3484567_17 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 361.0
HFD1_k127_3484567_18 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 355.0
HFD1_k127_3484567_19 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 339.0
HFD1_k127_3484567_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.121e-273 868.0
HFD1_k127_3484567_20 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 355.0
HFD1_k127_3484567_21 unusual protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 346.0
HFD1_k127_3484567_22 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 318.0
HFD1_k127_3484567_23 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 338.0
HFD1_k127_3484567_24 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 286.0
HFD1_k127_3484567_25 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003294 279.0
HFD1_k127_3484567_26 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002759 285.0
HFD1_k127_3484567_27 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002246 285.0
HFD1_k127_3484567_28 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
HFD1_k127_3484567_29 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002382 275.0
HFD1_k127_3484567_3 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 593.0
HFD1_k127_3484567_30 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004186 254.0
HFD1_k127_3484567_31 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000004307 256.0
HFD1_k127_3484567_32 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001275 249.0
HFD1_k127_3484567_33 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000001044 240.0
HFD1_k127_3484567_34 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000004851 237.0
HFD1_k127_3484567_35 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000025 231.0
HFD1_k127_3484567_36 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000002595 228.0
HFD1_k127_3484567_37 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
HFD1_k127_3484567_38 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000001215 217.0
HFD1_k127_3484567_39 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000112 213.0
HFD1_k127_3484567_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 567.0
HFD1_k127_3484567_40 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000005815 203.0
HFD1_k127_3484567_41 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000004515 201.0
HFD1_k127_3484567_42 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000127 189.0
HFD1_k127_3484567_43 - - - - 0.0000000000000000000000000000000000000000000000001097 185.0
HFD1_k127_3484567_44 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000007978 183.0
HFD1_k127_3484567_45 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000002897 184.0
HFD1_k127_3484567_46 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000001033 175.0
HFD1_k127_3484567_47 FAD binding domain - - - 0.000000000000000000000000000000000000000000001084 181.0
HFD1_k127_3484567_48 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000002863 166.0
HFD1_k127_3484567_49 Methyltransferase domain - - - 0.000000000000000000000000000000000000001412 156.0
HFD1_k127_3484567_5 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 562.0
HFD1_k127_3484567_50 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000000000000000000000000000000005066 148.0
HFD1_k127_3484567_51 Methyltransferase domain - - - 0.000000000000000000000000000000000001822 151.0
HFD1_k127_3484567_52 PFAM NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000001175 139.0
HFD1_k127_3484567_53 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000005625 136.0
HFD1_k127_3484567_54 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000006064 128.0
HFD1_k127_3484567_55 Tetratricopeptide repeat - - - 0.0000000000000000000000000000006145 141.0
HFD1_k127_3484567_56 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000007974 124.0
HFD1_k127_3484567_57 AraC-like ligand binding domain - - - 0.000000000000000000000000000001296 128.0
HFD1_k127_3484567_58 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000008425 119.0
HFD1_k127_3484567_59 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000003413 121.0
HFD1_k127_3484567_6 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 547.0
HFD1_k127_3484567_60 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000007172 112.0
HFD1_k127_3484567_61 Glycoprotease K14742 - - 0.0000000000000000000000000804 117.0
HFD1_k127_3484567_62 Putative adhesin - - - 0.0000000000000000000000006038 121.0
HFD1_k127_3484567_63 general stress protein - - - 0.0000000000000000000000008546 109.0
HFD1_k127_3484567_64 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.00000000000000000000001619 116.0
HFD1_k127_3484567_65 lipolytic protein G-D-S-L family - - - 0.00000000000000003702 84.0
HFD1_k127_3484567_66 - - - - 0.0000000005936 68.0
HFD1_k127_3484567_67 - - - - 0.000000005532 59.0
HFD1_k127_3484567_68 Gaf domain K03832 - - 0.00000000718 69.0
HFD1_k127_3484567_69 - - - - 0.000000007223 59.0
HFD1_k127_3484567_7 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 554.0
HFD1_k127_3484567_70 Protein of unknown function (DUF2911) - - - 0.00000001255 63.0
HFD1_k127_3484567_71 CAAX protease self-immunity - - - 0.00000002167 65.0
HFD1_k127_3484567_72 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000005164 64.0
HFD1_k127_3484567_73 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000003051 55.0
HFD1_k127_3484567_76 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.00004045 52.0
HFD1_k127_3484567_77 - - - - 0.00004389 46.0
HFD1_k127_3484567_8 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 524.0
HFD1_k127_3484567_9 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 490.0
HFD1_k127_3492325_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 409.0
HFD1_k127_3492325_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002979 276.0
HFD1_k127_3492325_2 Protein of unknown function (DUF4242) - - - 0.0000000000000000007895 88.0
HFD1_k127_3493235_0 Carboxypeptidase regulatory-like domain - - - 6.525e-303 964.0
HFD1_k127_3493235_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 631.0
HFD1_k127_3493235_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 627.0
HFD1_k127_3493235_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000004753 227.0
HFD1_k127_3493235_4 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - 0.00001184 56.0
HFD1_k127_3493549_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 302.0
HFD1_k127_3493549_1 Transposase - - - 0.00000000000000000000000000000000000001164 146.0
HFD1_k127_3498045_0 Tricorn protease C1 domain K08676 - - 0.0 1370.0
HFD1_k127_3498045_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1284.0
HFD1_k127_3498045_10 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 385.0
HFD1_k127_3498045_11 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 355.0
HFD1_k127_3498045_12 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 349.0
HFD1_k127_3498045_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 336.0
HFD1_k127_3498045_14 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 332.0
HFD1_k127_3498045_15 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 337.0
HFD1_k127_3498045_16 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 327.0
HFD1_k127_3498045_17 Serine aminopeptidase, S33 K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 308.0
HFD1_k127_3498045_18 Methyltransferase domain K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 302.0
HFD1_k127_3498045_19 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
HFD1_k127_3498045_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.853e-272 860.0
HFD1_k127_3498045_20 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
HFD1_k127_3498045_21 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 295.0
HFD1_k127_3498045_22 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000001319 261.0
HFD1_k127_3498045_23 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000001076 232.0
HFD1_k127_3498045_24 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000007058 224.0
HFD1_k127_3498045_25 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000001714 211.0
HFD1_k127_3498045_26 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000006612 218.0
HFD1_k127_3498045_27 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000001629 203.0
HFD1_k127_3498045_28 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000001513 178.0
HFD1_k127_3498045_29 DoxX - - - 0.00000000000000000000000000000000000000000001357 168.0
HFD1_k127_3498045_3 Amidohydrolase family - - - 4.022e-249 778.0
HFD1_k127_3498045_30 EthD domain - - - 0.0000000000000000000000000000000000002151 143.0
HFD1_k127_3498045_31 Protein of unknown function (DUF3303) - - - 0.00000000000000000000000000006091 119.0
HFD1_k127_3498045_32 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000001065 124.0
HFD1_k127_3498045_33 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000001314 116.0
HFD1_k127_3498045_34 HEAT repeat - - - 0.0000000000000000000000002592 118.0
HFD1_k127_3498045_35 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.000000000000000000000001618 112.0
HFD1_k127_3498045_36 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000001197 102.0
HFD1_k127_3498045_37 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000004701 70.0
HFD1_k127_3498045_38 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000007386 68.0
HFD1_k127_3498045_39 CBS domain - - - 0.00000003376 61.0
HFD1_k127_3498045_4 PFAM Amidase - - - 8.191e-199 635.0
HFD1_k127_3498045_40 Tetratricopeptide repeat - - - 0.0002017 53.0
HFD1_k127_3498045_5 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 532.0
HFD1_k127_3498045_6 Aldo Keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 492.0
HFD1_k127_3498045_7 Metalloenzyme superfamily K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 469.0
HFD1_k127_3498045_8 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006578 469.0
HFD1_k127_3498045_9 PFAM Acetamidase Formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 457.0
HFD1_k127_3500576_0 - - - - 0.00000000000000000000006374 104.0
HFD1_k127_3500576_1 ORF located using Blastx - - - 0.0000000003788 63.0
HFD1_k127_3500576_2 - - - - 0.00002134 51.0
HFD1_k127_3521620_0 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 445.0
HFD1_k127_3521620_1 PFAM Transposase domain (DUF772) - - - 0.000000000000000000004349 95.0
HFD1_k127_3558549_0 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001162 250.0
HFD1_k127_3561978_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000002407 255.0
HFD1_k127_3561978_1 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000004418 180.0
HFD1_k127_3564771_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 544.0
HFD1_k127_359496_0 cytochrome c peroxidase K00428 - 1.11.1.5 2.748e-236 755.0
HFD1_k127_359496_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 552.0
HFD1_k127_359496_10 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000005859 232.0
HFD1_k127_359496_11 Protein of unknown function (DUF969) - - - 0.0000000000000000000000000000000000000000000000000001693 194.0
HFD1_k127_359496_13 hyperosmotic response - - - 0.000000001365 68.0
HFD1_k127_359496_2 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 500.0
HFD1_k127_359496_3 D-arabinono-1,4-lactone oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 460.0
HFD1_k127_359496_4 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 449.0
HFD1_k127_359496_5 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 418.0
HFD1_k127_359496_6 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 300.0
HFD1_k127_359496_7 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 295.0
HFD1_k127_359496_8 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002136 286.0
HFD1_k127_359496_9 Protein of unknown function (DUF979) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001942 261.0
HFD1_k127_3602638_0 choline dehydrogenase activity - - - 8.067e-241 755.0
HFD1_k127_3602638_1 Histidine kinase K02480,K07683 - 2.7.13.3 8.054e-221 724.0
HFD1_k127_3602638_10 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000000000000000000000000000000000002205 166.0
HFD1_k127_3602638_11 BMC K04025 - - 0.00000000000000000000000000000000000007494 151.0
HFD1_k127_3602638_12 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000001799 138.0
HFD1_k127_3602638_13 Domain of unknown function (DUF4252) - - - 0.0000000000000000000000000000000005794 139.0
HFD1_k127_3602638_14 response regulator K02282 - - 0.00000000000000000000000000000009138 127.0
HFD1_k127_3602638_15 - - - - 0.00000000000000000000000001051 111.0
HFD1_k127_3602638_16 RNA polymerase II activating transcription factor binding - - - 0.00000000000002566 80.0
HFD1_k127_3602638_17 - - - - 0.00007181 52.0
HFD1_k127_3602638_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 581.0
HFD1_k127_3602638_3 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 378.0
HFD1_k127_3602638_4 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 340.0
HFD1_k127_3602638_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000041 289.0
HFD1_k127_3602638_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003228 282.0
HFD1_k127_3602638_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000001212 247.0
HFD1_k127_3602638_8 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000003848 216.0
HFD1_k127_3602638_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000233 190.0
HFD1_k127_3603055_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1760.0
HFD1_k127_3603055_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1148.0
HFD1_k127_3603055_10 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 417.0
HFD1_k127_3603055_11 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 410.0
HFD1_k127_3603055_12 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 394.0
HFD1_k127_3603055_13 MaoC like domain K14449,K18290 - 4.2.1.148,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 359.0
HFD1_k127_3603055_14 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 347.0
HFD1_k127_3603055_15 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 335.0
HFD1_k127_3603055_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 344.0
HFD1_k127_3603055_17 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 309.0
HFD1_k127_3603055_18 Phosphatidate cytidylyltransferase K00981 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 307.0
HFD1_k127_3603055_19 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 289.0
HFD1_k127_3603055_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1062.0
HFD1_k127_3603055_20 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001501 293.0
HFD1_k127_3603055_21 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004019 263.0
HFD1_k127_3603055_22 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005455 251.0
HFD1_k127_3603055_23 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002872 246.0
HFD1_k127_3603055_24 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000000000000000000000001166 237.0
HFD1_k127_3603055_25 Caulimovirus viroplasmin K06993 - - 0.00000000000000000000000000000000000000000000000000000000000000001037 237.0
HFD1_k127_3603055_26 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000647 224.0
HFD1_k127_3603055_27 DNA recombination-mediator protein A - - - 0.00000000000000000000000000000000000000000000000000000000000008843 226.0
HFD1_k127_3603055_28 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000008951 199.0
HFD1_k127_3603055_29 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000001804 194.0
HFD1_k127_3603055_3 helicase superfamily c-terminal domain K03654 - 3.6.4.12 1.294e-244 774.0
HFD1_k127_3603055_31 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000001606 187.0
HFD1_k127_3603055_32 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000005304 195.0
HFD1_k127_3603055_33 Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid K05714 - 3.7.1.14 0.0000000000000000000000000000000000000000000009477 181.0
HFD1_k127_3603055_34 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000001837 172.0
HFD1_k127_3603055_36 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000001006 165.0
HFD1_k127_3603055_37 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000006333 158.0
HFD1_k127_3603055_38 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000004998 135.0
HFD1_k127_3603055_39 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000001945 136.0
HFD1_k127_3603055_4 Pyrrolo-quinoline quinone - - - 4.793e-227 722.0
HFD1_k127_3603055_41 Lysozyme inhibitor LprI - - - 0.00000000000000000000002146 104.0
HFD1_k127_3603055_42 Evidence 4 Homologs of previously reported genes of K21440 - - 0.00000000000000000002488 97.0
HFD1_k127_3603055_43 Uncharacterized ACR, COG1993 K09137 - - 0.00000000003363 68.0
HFD1_k127_3603055_44 - - - - 0.0000008161 60.0
HFD1_k127_3603055_45 - - - - 0.00001605 55.0
HFD1_k127_3603055_5 Peptidase S46 - - - 3.734e-214 687.0
HFD1_k127_3603055_6 Oxidoreductase domain protein - - - 6.048e-204 640.0
HFD1_k127_3603055_7 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 525.0
HFD1_k127_3603055_8 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 465.0
HFD1_k127_3603055_9 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 459.0
HFD1_k127_3645990_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 349.0
HFD1_k127_3701155_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 505.0
HFD1_k127_3701155_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 429.0
HFD1_k127_3701155_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 293.0
HFD1_k127_3701155_3 PFAM Uncharacterised protein family UPF0150 K18843 - - 0.00000000000000000000000000006383 118.0
HFD1_k127_3701155_4 HicA toxin of bacterial toxin-antitoxin, K07339 - - 0.00000000000000000007727 91.0
HFD1_k127_3720162_0 transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 337.0
HFD1_k127_3720162_1 There are 9 addittional ORFs identical to this one - - - 0.000000000000000000000000000000000000000000000000000000001341 211.0
HFD1_k127_373981_0 - - - - 0.000000000001237 73.0
HFD1_k127_373981_1 Methyltransferase FkbM domain - - - 0.000000000001539 81.0
HFD1_k127_373981_2 Glycosyltransferase Family 4 - - - 0.0000005489 63.0
HFD1_k127_375569_0 - - - - 0.0000000000000000000000000000000001943 133.0
HFD1_k127_375569_1 - - - - 0.00000000000000001839 83.0
HFD1_k127_375569_4 - - - - 0.0000879 45.0
HFD1_k127_3776000_0 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 355.0
HFD1_k127_3776000_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000003248 90.0
HFD1_k127_3828641_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000004091 105.0
HFD1_k127_38410_0 Trypsin-like peptidase domain - - - 0.0000002637 54.0
HFD1_k127_3863511_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 488.0
HFD1_k127_3863511_1 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000005012 181.0
HFD1_k127_3902361_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005735 282.0
HFD1_k127_3902361_1 - - - - 0.0000000000000000000000000000000000000000000001473 188.0
HFD1_k127_3929911_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 329.0
HFD1_k127_3929911_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000008172 209.0
HFD1_k127_3929911_2 PFAM Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.00000000000000000000000000000000000000001056 169.0
HFD1_k127_3929911_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000458 158.0
HFD1_k127_3929911_4 polysaccharide deacetylase - - - 0.0000000000000000000005084 108.0
HFD1_k127_3929911_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000003856 99.0
HFD1_k127_393794_0 - - - - 0.00000000000000000000009045 109.0
HFD1_k127_4020914_0 Ribonuclease H protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 390.0
HFD1_k127_4021768_0 Arylsulfatase a K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 365.0
HFD1_k127_4021768_1 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000224 162.0
HFD1_k127_4021768_3 - - - - 0.00000288 49.0
HFD1_k127_4023905_0 Belongs to the UbiD family K03182 - 4.1.1.98 8.307e-209 661.0
HFD1_k127_4023905_1 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 502.0
HFD1_k127_4023905_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000004187 60.0
HFD1_k127_4023905_11 S-layer homology domain - - - 0.0002588 50.0
HFD1_k127_4023905_2 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 452.0
HFD1_k127_4023905_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 314.0
HFD1_k127_4023905_4 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 305.0
HFD1_k127_4023905_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 290.0
HFD1_k127_4023905_6 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000009224 258.0
HFD1_k127_4023905_7 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000004674 152.0
HFD1_k127_4023905_8 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000004635 69.0
HFD1_k127_4023905_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000008954 75.0
HFD1_k127_4037565_0 Uncharacterised protein family (UPF0182) K09118 - - 8.654e-221 719.0
HFD1_k127_4037565_1 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 371.0
HFD1_k127_4037565_2 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 373.0
HFD1_k127_4037565_3 ABC-type transport system involved in multi-copper enzyme maturation K01992 - - 0.0000000000000000000000000000000000000000000000000000000000002196 220.0
HFD1_k127_4037565_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000005641 177.0
HFD1_k127_4037565_5 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000001496 161.0
HFD1_k127_4037565_6 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000001075 124.0
HFD1_k127_4037565_7 Domain of unknown function (DUF4340) - - - 0.00001858 57.0
HFD1_k127_4039817_0 PFAM 4Fe-4S binding domain - - - 6.198e-204 643.0
HFD1_k127_4039817_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000001306 224.0
HFD1_k127_404481_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0 1017.0
HFD1_k127_404481_1 PFAM Glycosyl hydrolases family 31 K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 615.0
HFD1_k127_4045033_0 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000001377 60.0
HFD1_k127_404537_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000004028 250.0
HFD1_k127_4049687_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1055.0
HFD1_k127_4049687_1 TIGRFAM rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - 2.546e-319 994.0
HFD1_k127_4049687_10 Glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 585.0
HFD1_k127_4049687_11 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 581.0
HFD1_k127_4049687_12 Coagulation factor 5 8 type domain protein K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 565.0
HFD1_k127_4049687_13 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 551.0
HFD1_k127_4049687_14 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 502.0
HFD1_k127_4049687_15 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 474.0
HFD1_k127_4049687_16 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 495.0
HFD1_k127_4049687_17 beta-galactosidase activity K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 431.0
HFD1_k127_4049687_18 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 420.0
HFD1_k127_4049687_19 carbohydrate kinase FGGY K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 424.0
HFD1_k127_4049687_2 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 9.529e-286 897.0
HFD1_k127_4049687_20 inositol monophosphate 1-phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 414.0
HFD1_k127_4049687_21 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 391.0
HFD1_k127_4049687_22 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 387.0
HFD1_k127_4049687_23 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 359.0
HFD1_k127_4049687_24 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 325.0
HFD1_k127_4049687_25 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 317.0
HFD1_k127_4049687_26 Dual specificity phosphatase, catalytic domain K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 326.0
HFD1_k127_4049687_27 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002882 278.0
HFD1_k127_4049687_28 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000009015 263.0
HFD1_k127_4049687_29 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009963 254.0
HFD1_k127_4049687_3 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 3.489e-264 832.0
HFD1_k127_4049687_30 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000007803 240.0
HFD1_k127_4049687_31 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000003245 193.0
HFD1_k127_4049687_32 Acyl-transferase - - - 0.00000000000000000000000000000000000000005253 162.0
HFD1_k127_4049687_33 Oligogalacturonate lyase K01730 - 4.2.2.6 0.000000000000000000004166 98.0
HFD1_k127_4049687_34 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000001656 96.0
HFD1_k127_4049687_35 PFAM ROK family - - - 0.00000000000000003794 87.0
HFD1_k127_4049687_36 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000005972 70.0
HFD1_k127_4049687_37 D-galactarate dehydratase / Altronate hydrolase, C terminus - - - 0.0000002137 58.0
HFD1_k127_4049687_38 Belongs to the glycosyl hydrolase 28 family K19172 - - 0.000001378 53.0
HFD1_k127_4049687_39 Trypsin - GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006508,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009507,GO:0009526,GO:0009532,GO:0009533,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009657,GO:0009658,GO:0009765,GO:0009941,GO:0009987,GO:0010206,GO:0015979,GO:0016020,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0019684,GO:0030091,GO:0030163,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000003165 58.0
HFD1_k127_4049687_4 Alpha-L-rhamnosidase - - - 1.194e-258 826.0
HFD1_k127_4049687_40 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins - - - 0.0001461 47.0
HFD1_k127_4049687_5 PFAM carbohydrate kinase K00854 - 2.7.1.17 3.045e-221 695.0
HFD1_k127_4049687_6 mandelate racemase muconate lactonizing K08323 - 4.2.1.8 6.638e-215 671.0
HFD1_k127_4049687_7 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 605.0
HFD1_k127_4049687_8 isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 601.0
HFD1_k127_4049687_9 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 605.0
HFD1_k127_4051363_0 Tricorn protease PDZ domain K08676 - - 0.0 1275.0
HFD1_k127_4051363_1 Tricorn protease PDZ domain K08676 - - 0.0 1266.0
HFD1_k127_4051363_10 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 463.0
HFD1_k127_4051363_11 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 350.0
HFD1_k127_4051363_12 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 292.0
HFD1_k127_4051363_13 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001828 259.0
HFD1_k127_4051363_14 peptidase S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000001186 243.0
HFD1_k127_4051363_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000005974 218.0
HFD1_k127_4051363_16 PFAM Cache K08738 - - 0.0000000000000000000000000000000000000000000000000000000000001283 234.0
HFD1_k127_4051363_17 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000001964 218.0
HFD1_k127_4051363_18 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000000000000000000002509 206.0
HFD1_k127_4051363_19 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000008489 177.0
HFD1_k127_4051363_2 Tricorn protease PDZ domain K08676 - - 3.417e-235 765.0
HFD1_k127_4051363_20 lactoylglutathione lyase activity - - - 0.00000000000000000000000000003356 120.0
HFD1_k127_4051363_21 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000022 118.0
HFD1_k127_4051363_22 - - - - 0.000000000000000000004336 97.0
HFD1_k127_4051363_23 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000002604 96.0
HFD1_k127_4051363_24 Putative diguanylate phosphodiesterase - - - 0.0000000008535 72.0
HFD1_k127_4051363_25 Transcriptional regulatory protein, C terminal - - - 0.0002383 48.0
HFD1_k127_4051363_3 efflux transmembrane transporter activity K02004 - - 3.864e-230 737.0
HFD1_k127_4051363_4 efflux transmembrane transporter activity - - - 2.477e-223 718.0
HFD1_k127_4051363_5 efflux transmembrane transporter activity - - - 7.448e-209 677.0
HFD1_k127_4051363_6 FtsX-like permease family - - - 6.062e-206 672.0
HFD1_k127_4051363_7 efflux transmembrane transporter activity K02004 - - 1.457e-203 659.0
HFD1_k127_4051363_8 efflux transmembrane transporter activity - - - 6.193e-199 647.0
HFD1_k127_4051363_9 PFAM Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 545.0
HFD1_k127_405733_0 K02A2.6-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 342.0
HFD1_k127_4057403_0 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000011 200.0
HFD1_k127_4057403_1 cytochrome C peroxidase - - - 0.00001736 53.0
HFD1_k127_4062212_0 IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 576.0
HFD1_k127_4067349_0 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 5.607e-231 723.0
HFD1_k127_4067349_1 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 420.0
HFD1_k127_4067349_2 (Rhomboid) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 333.0
HFD1_k127_4067349_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 293.0
HFD1_k127_4067349_4 - - - - 0.000000000000000000000000000000000000000000000000000000164 200.0
HFD1_k127_4067349_5 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000005378 198.0
HFD1_k127_4067349_6 Peptidase, M16 K07263,K07623 - - 0.0000000006307 70.0
HFD1_k127_4075977_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.647e-262 817.0
HFD1_k127_4075977_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 4.387e-201 657.0
HFD1_k127_4075977_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 488.0
HFD1_k127_4075977_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 475.0
HFD1_k127_4075977_4 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 396.0
HFD1_k127_4075977_5 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 320.0
HFD1_k127_4075977_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000001777 129.0
HFD1_k127_4075977_7 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000006998 113.0
HFD1_k127_4082992_0 IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 281.0
HFD1_k127_4084335_0 COG5659 FOG Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 436.0
HFD1_k127_4084335_1 Protein of unknown function, DUF488 - - - 0.000000000000000000000000003871 114.0
HFD1_k127_4085497_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1244.0
HFD1_k127_4085497_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 296.0
HFD1_k127_4085497_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008428 240.0
HFD1_k127_4085497_3 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000001172 222.0
HFD1_k127_4085497_5 - - - - 0.00000000000000000000000000000000000000001708 160.0
HFD1_k127_4085497_6 chlorophyll binding - - - 0.0000000000000000000000004461 117.0
HFD1_k127_4085497_7 Belongs to the ompA family - - - 0.00000000000000000105 97.0
HFD1_k127_4085497_8 Domain of unknown function (DUF4956) - - - 0.0000000008783 70.0
HFD1_k127_4085594_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000001306 199.0
HFD1_k127_4108856_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002276 276.0
HFD1_k127_4112235_0 TonB-dependent receptor - - - 1.046e-247 802.0
HFD1_k127_4112235_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 617.0
HFD1_k127_4112235_10 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 293.0
HFD1_k127_4112235_11 Periplasmic binding protein-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 289.0
HFD1_k127_4112235_12 PFAM Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000005787 262.0
HFD1_k127_4112235_13 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000004955 248.0
HFD1_k127_4112235_14 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000005188 258.0
HFD1_k127_4112235_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007413 255.0
HFD1_k127_4112235_16 Domain of unknown function (DUF4287) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001701 241.0
HFD1_k127_4112235_17 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000001043 246.0
HFD1_k127_4112235_18 Subtilase family K14645 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000000000005047 247.0
HFD1_k127_4112235_19 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000001971 203.0
HFD1_k127_4112235_2 TIGRFAM glutamine synthetase, type I K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 595.0
HFD1_k127_4112235_20 COG3622 Hydroxypyruvate isomerase K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000001466 198.0
HFD1_k127_4112235_21 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000003066 192.0
HFD1_k127_4112235_22 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000562 178.0
HFD1_k127_4112235_23 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000004589 166.0
HFD1_k127_4112235_24 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000001974 134.0
HFD1_k127_4112235_26 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000007364 138.0
HFD1_k127_4112235_27 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000001787 134.0
HFD1_k127_4112235_28 Belongs to the ompA family - - - 0.0000000000000000000000001796 115.0
HFD1_k127_4112235_29 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000002985 110.0
HFD1_k127_4112235_3 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 504.0
HFD1_k127_4112235_31 Periplasmic or secreted lipoprotein - - - 0.0000000000001309 80.0
HFD1_k127_4112235_32 Matrixin - - - 0.000000000002637 80.0
HFD1_k127_4112235_33 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00001994 57.0
HFD1_k127_4112235_4 sequence-specific DNA binding K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 424.0
HFD1_k127_4112235_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 394.0
HFD1_k127_4112235_6 Zinc-binding dehydrogenase K17818 - 1.1.1.287 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 382.0
HFD1_k127_4112235_7 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 347.0
HFD1_k127_4112235_8 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 346.0
HFD1_k127_4112235_9 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 331.0
HFD1_k127_4119669_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1167.0
HFD1_k127_4119669_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.0 1044.0
HFD1_k127_4119669_10 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000009511 190.0
HFD1_k127_4119669_11 Protein of unknown function (DUF4199) - - - 0.000000000000000001085 91.0
HFD1_k127_4119669_12 Protein of unknown function (DUF4199) - - - 0.00000000000000007036 86.0
HFD1_k127_4119669_13 Glycine D-amino acid oxidase (deaminating) - - - 0.00000003183 56.0
HFD1_k127_4119669_14 Polyketide cyclase dehydrase and lipid transport - - - 0.000004993 55.0
HFD1_k127_4119669_15 marr family - - - 0.0004568 49.0
HFD1_k127_4119669_2 Sortilin, neurotensin receptor 3, - - - 8.462e-314 986.0
HFD1_k127_4119669_3 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 4.553e-299 934.0
HFD1_k127_4119669_4 - - - - 1.782e-266 850.0
HFD1_k127_4119669_5 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 4.781e-243 759.0
HFD1_k127_4119669_6 Beta-L-arabinofuranosidase, GH127 K09955 - - 7.195e-214 691.0
HFD1_k127_4119669_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 384.0
HFD1_k127_4119669_8 DNA-binding transcription factor activity K02081,K02444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002235 266.0
HFD1_k127_4119669_9 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004475 256.0
HFD1_k127_4121933_0 peptidase K01415,K07386 - 3.4.24.71 1.044e-300 934.0
HFD1_k127_4121933_1 GAF domain - - - 2.892e-246 803.0
HFD1_k127_4121933_10 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000001149 260.0
HFD1_k127_4121933_11 ABC transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000001189 232.0
HFD1_k127_4121933_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000002938 226.0
HFD1_k127_4121933_13 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000001323 184.0
HFD1_k127_4121933_14 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000001591 161.0
HFD1_k127_4121933_15 Appr-1'-p processing enzyme - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000001224 153.0
HFD1_k127_4121933_16 domain, Protein K07004 - - 0.0000000000000000000000000000000000332 148.0
HFD1_k127_4121933_17 Belongs to the ompA family - - - 0.0000000000000000000000000000003519 132.0
HFD1_k127_4121933_18 - - - - 0.000000004095 65.0
HFD1_k127_4121933_2 glutamate decarboxylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 596.0
HFD1_k127_4121933_3 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 544.0
HFD1_k127_4121933_4 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 497.0
HFD1_k127_4121933_5 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 414.0
HFD1_k127_4121933_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 402.0
HFD1_k127_4121933_7 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 374.0
HFD1_k127_4121933_8 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 336.0
HFD1_k127_4121933_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 303.0
HFD1_k127_4124385_0 -O-antigen - - - 0.00000000000000000000000000000000000000000000003708 187.0
HFD1_k127_4124976_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000003151 208.0
HFD1_k127_4124976_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.000000000000000000000000000000000000000000005833 169.0
HFD1_k127_4124976_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000002838 155.0
HFD1_k127_4124976_3 Transposase K07492 - - 0.000000000000000000000000000416 119.0
HFD1_k127_4149009_0 cellulose binding - - - 0.0 1109.0
HFD1_k127_4149009_1 Response regulator receiver - - - 4.468e-203 640.0
HFD1_k127_4149009_10 TIR domain - - - 0.00000006597 63.0
HFD1_k127_4149009_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 562.0
HFD1_k127_4149009_3 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 438.0
HFD1_k127_4149009_4 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 369.0
HFD1_k127_4149009_5 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 358.0
HFD1_k127_4149009_6 PFAM Calcineurin-like phosphoesterase K07099 - - 0.000000000000000000000000000000000000000000000000000000000000000004885 233.0
HFD1_k127_4149009_7 - - - - 0.000000000000000000000000000000000000000000000000000001057 197.0
HFD1_k127_4149009_8 - - - - 0.0000000000000000000000000000000000000000006926 166.0
HFD1_k127_4149009_9 - - - - 0.00000000000000000000000000384 115.0
HFD1_k127_4171346_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 436.0
HFD1_k127_418271_0 Transposase zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009016 282.0
HFD1_k127_418271_1 MobA MobL family protein - - - 0.000000000000000000000000000000000000000002318 169.0
HFD1_k127_4186534_0 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 552.0
HFD1_k127_4186534_1 IS1 transposase K07480 - - 0.00000000000000000000000000000000000000000000000000000000004329 208.0
HFD1_k127_4186534_2 InsA C-terminal domain - - - 0.00000000000000000000002744 102.0
HFD1_k127_4190631_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1135.0
HFD1_k127_4190631_1 Acyclic terpene utilisation family protein AtuA - - - 1.944e-197 624.0
HFD1_k127_4190631_10 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000001654 109.0
HFD1_k127_4190631_11 - - - - 0.000000000000000001306 92.0
HFD1_k127_4190631_12 Cupredoxin-like domain - - - 0.00000000000001283 87.0
HFD1_k127_4190631_13 Transposase - - - 0.00003149 46.0
HFD1_k127_4190631_2 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 399.0
HFD1_k127_4190631_3 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.000000000000000000000000000000000000000000000000000001936 199.0
HFD1_k127_4190631_4 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000005417 178.0
HFD1_k127_4190631_5 Biotin-lipoyl like K15727 - - 0.0000000000000000000000000000000000000000003488 178.0
HFD1_k127_4190631_6 - - - - 0.000000000000000000000000000000000000000006647 156.0
HFD1_k127_4190631_7 Transposase IS200 like K07491 - - 0.0000000000000000000000000000007991 126.0
HFD1_k127_4190631_8 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000000214 104.0
HFD1_k127_4190631_9 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000002166 104.0
HFD1_k127_4199417_0 Alcohol dehydrogenase GroES-like domain K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 381.0
HFD1_k127_4199417_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 341.0
HFD1_k127_4199417_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 336.0
HFD1_k127_4199417_3 Ribosomal RNA adenine dimethylases K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000003687 222.0
HFD1_k127_4199417_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000001865 201.0
HFD1_k127_4199417_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001704 189.0
HFD1_k127_4199417_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000008018 165.0
HFD1_k127_4199417_7 - K07164 - - 0.0006697 45.0
HFD1_k127_4223324_0 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 409.0
HFD1_k127_4225952_0 Putative transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 456.0
HFD1_k127_4225952_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 292.0
HFD1_k127_4225952_2 Alpha/beta hydrolase family - - - 0.00000000000006627 71.0
HFD1_k127_4226312_0 PQQ-like domain K00114 - 1.1.2.8 5.255e-241 754.0
HFD1_k127_4226312_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 408.0
HFD1_k127_4226312_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000001146 227.0
HFD1_k127_4244546_0 - - - - 0.0000005419 54.0
HFD1_k127_4275214_0 the current gene model (or a revised gene model) may contain a premature stop - - - 0.00000000000000000000000001185 111.0
HFD1_k127_4277905_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002159 278.0
HFD1_k127_4277905_1 Ankyrin repeat - - - 0.0000000003429 65.0
HFD1_k127_4280386_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 554.0
HFD1_k127_4280386_1 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000374 166.0
HFD1_k127_4280386_2 - - - - 0.000000000000000000000000000000000000000003656 169.0
HFD1_k127_4280386_3 Two component signalling adaptor domain K03408 - - 0.0000000000000000001947 88.0
HFD1_k127_4283614_0 LVIVD repeat - - - 0.0 1375.0
HFD1_k127_4283614_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1110.0
HFD1_k127_4283614_10 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 595.0
HFD1_k127_4283614_100 Protein of unknown function (DUF1573) - - - 0.0001569 48.0
HFD1_k127_4283614_11 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 591.0
HFD1_k127_4283614_12 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 585.0
HFD1_k127_4283614_13 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 535.0
HFD1_k127_4283614_14 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 512.0
HFD1_k127_4283614_15 FAD linked oxidase domain protein K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 503.0
HFD1_k127_4283614_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 494.0
HFD1_k127_4283614_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 472.0
HFD1_k127_4283614_18 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 467.0
HFD1_k127_4283614_19 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 467.0
HFD1_k127_4283614_2 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 2.39e-321 1009.0
HFD1_k127_4283614_20 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 471.0
HFD1_k127_4283614_21 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 465.0
HFD1_k127_4283614_22 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 444.0
HFD1_k127_4283614_23 glycogen (starch) synthase activity K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 443.0
HFD1_k127_4283614_24 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 411.0
HFD1_k127_4283614_25 4Fe-4S binding domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 396.0
HFD1_k127_4283614_26 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 369.0
HFD1_k127_4283614_27 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 323.0
HFD1_k127_4283614_28 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0
HFD1_k127_4283614_29 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
HFD1_k127_4283614_3 Belongs to the transketolase family K00615 - 2.2.1.1 4.803e-315 976.0
HFD1_k127_4283614_30 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 313.0
HFD1_k127_4283614_31 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 298.0
HFD1_k127_4283614_32 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 306.0
HFD1_k127_4283614_33 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 304.0
HFD1_k127_4283614_34 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002252 300.0
HFD1_k127_4283614_35 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003591 281.0
HFD1_k127_4283614_36 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
HFD1_k127_4283614_37 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002191 301.0
HFD1_k127_4283614_38 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
HFD1_k127_4283614_39 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003965 266.0
HFD1_k127_4283614_4 B12 binding domain - - - 3.711e-238 746.0
HFD1_k127_4283614_40 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000654 264.0
HFD1_k127_4283614_41 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001973 267.0
HFD1_k127_4283614_42 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000806 263.0
HFD1_k127_4283614_43 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001138 224.0
HFD1_k127_4283614_44 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000007974 222.0
HFD1_k127_4283614_45 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000001411 224.0
HFD1_k127_4283614_46 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000001831 233.0
HFD1_k127_4283614_47 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000008993 217.0
HFD1_k127_4283614_48 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000472 215.0
HFD1_k127_4283614_49 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000001482 217.0
HFD1_k127_4283614_5 Transcriptional regulator K06921 - - 3.03e-228 738.0
HFD1_k127_4283614_50 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000004783 223.0
HFD1_k127_4283614_51 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000008027 218.0
HFD1_k127_4283614_52 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000004061 203.0
HFD1_k127_4283614_53 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000005673 193.0
HFD1_k127_4283614_54 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000001022 194.0
HFD1_k127_4283614_55 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.000000000000000000000000000000000000000000000000000001183 220.0
HFD1_k127_4283614_56 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000001859 198.0
HFD1_k127_4283614_57 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000003372 190.0
HFD1_k127_4283614_58 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000007517 181.0
HFD1_k127_4283614_59 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000002656 179.0
HFD1_k127_4283614_6 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 2.115e-200 636.0
HFD1_k127_4283614_60 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000005575 177.0
HFD1_k127_4283614_61 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000005759 174.0
HFD1_k127_4283614_62 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000347 191.0
HFD1_k127_4283614_63 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000006088 173.0
HFD1_k127_4283614_64 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000002794 169.0
HFD1_k127_4283614_65 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000000000000000000000000003449 179.0
HFD1_k127_4283614_66 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000114 176.0
HFD1_k127_4283614_67 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000002709 152.0
HFD1_k127_4283614_68 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000003337 153.0
HFD1_k127_4283614_69 Lysin motif - - - 0.00000000000000000000000000000000000001704 151.0
HFD1_k127_4283614_7 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 3.664e-200 633.0
HFD1_k127_4283614_70 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000002145 146.0
HFD1_k127_4283614_71 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000000000000000004575 144.0
HFD1_k127_4283614_72 DinB superfamily K07552 - - 0.000000000000000000000000000000000001691 144.0
HFD1_k127_4283614_73 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000008997 138.0
HFD1_k127_4283614_74 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000007285 133.0
HFD1_k127_4283614_75 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000003047 135.0
HFD1_k127_4283614_76 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000001029 125.0
HFD1_k127_4283614_77 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000002224 131.0
HFD1_k127_4283614_78 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000001808 127.0
HFD1_k127_4283614_79 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000003706 105.0
HFD1_k127_4283614_8 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 613.0
HFD1_k127_4283614_80 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000007849 106.0
HFD1_k127_4283614_81 Thioredoxin - - - 0.0000000000000000001224 103.0
HFD1_k127_4283614_82 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000002608 91.0
HFD1_k127_4283614_83 GrpB protein - - - 0.000000000000000003555 92.0
HFD1_k127_4283614_84 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000115 82.0
HFD1_k127_4283614_85 Domain of unknown function (DUF309) K09763 - - 0.0000000000000002702 88.0
HFD1_k127_4283614_86 Ribosomal protein L30 K02907 - - 0.0000000000000003463 79.0
HFD1_k127_4283614_87 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000009548 79.0
HFD1_k127_4283614_88 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001576 74.0
HFD1_k127_4283614_89 His Kinase A (phosphoacceptor) domain - - - 0.00000000000007904 79.0
HFD1_k127_4283614_9 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 594.0
HFD1_k127_4283614_90 12 heme-binding sites - - - 0.0000000000009827 79.0
HFD1_k127_4283614_91 Ribosomal L29 protein K02904 - - 0.0000000001668 66.0
HFD1_k127_4283614_92 IMG reference gene - - - 0.0000000002666 70.0
HFD1_k127_4283614_93 Forkhead associated domain - - - 0.000000001634 68.0
HFD1_k127_4283614_94 PFAM Cytochrome c, bacterial - - - 0.00000001388 64.0
HFD1_k127_4283614_95 FHA domain - - - 0.0000002225 65.0
HFD1_k127_4283614_96 Putative zinc- or iron-chelating domain K06940 - - 0.00001708 52.0
HFD1_k127_4283614_97 TIGRFAM cytochrome C family protein - - - 0.00002109 56.0
HFD1_k127_4283614_98 PFAM Cytochrome c, bacterial - - - 0.00002786 57.0
HFD1_k127_4283614_99 Protein of unknown function (DUF2934) - - - 0.00003034 49.0
HFD1_k127_4291095_0 Putative transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 432.0
HFD1_k127_4291095_1 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 308.0
HFD1_k127_4292673_0 Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 346.0
HFD1_k127_43216_0 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000003057 238.0
HFD1_k127_4328405_0 Transposase, Mutator family - - - 2.504e-231 720.0
HFD1_k127_4328405_1 - - - - 0.000000000000000000000000000000000000003132 147.0
HFD1_k127_4328405_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000007615 108.0
HFD1_k127_4328405_3 COG3316 Transposase and inactivated derivatives K07498 - - 0.000000000000000000006122 93.0
HFD1_k127_4328405_4 COG3316 Transposase and inactivated derivatives K07498 - - 0.000001426 51.0
HFD1_k127_4365332_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 288.0
HFD1_k127_4365332_1 Homeodomain-like domain - - - 0.000000000000000000000000000000000002053 144.0
HFD1_k127_4365332_2 ribonuclease BN K07058 - - 0.000000000000000000001051 96.0
HFD1_k127_4367215_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.572e-233 736.0
HFD1_k127_4367215_1 Nickel-dependent hydrogenase - - - 8.928e-217 678.0
HFD1_k127_4367215_10 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001487 241.0
HFD1_k127_4367215_11 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000004782 211.0
HFD1_k127_4367215_12 HD domain - - - 0.000000000000000000000000000000000000000000000004689 189.0
HFD1_k127_4367215_13 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000006189 175.0
HFD1_k127_4367215_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000005158 145.0
HFD1_k127_4367215_15 Hydrogenase maturation protease - - - 0.000000000000000000000000000000005694 133.0
HFD1_k127_4367215_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000008137 101.0
HFD1_k127_4367215_17 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000007781 90.0
HFD1_k127_4367215_18 Domain of unknown function (DUF4384) - - - 0.0000000000001433 79.0
HFD1_k127_4367215_19 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000001159 78.0
HFD1_k127_4367215_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.683e-215 676.0
HFD1_k127_4367215_20 Domain of unknown function (DUF4384) - - - 0.00000007205 63.0
HFD1_k127_4367215_21 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000001383 55.0
HFD1_k127_4367215_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 537.0
HFD1_k127_4367215_4 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 455.0
HFD1_k127_4367215_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 460.0
HFD1_k127_4367215_6 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 379.0
HFD1_k127_4367215_7 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002681 250.0
HFD1_k127_4367215_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009664 239.0
HFD1_k127_4367215_9 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001903 250.0
HFD1_k127_4367745_0 Galactose oxidase, central domain - - - 0.000000000000000003785 89.0
HFD1_k127_4367745_1 Endonuclease-reverse transcriptase - - - 0.0002464 51.0
HFD1_k127_4369168_0 Prolyl oligopeptidase family K01303 - 3.4.19.1 7.212e-220 703.0
HFD1_k127_4369168_1 regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000004582 212.0
HFD1_k127_4369168_2 - - - - 0.000000000000000000000000000000000005906 142.0
HFD1_k127_4369168_3 - - - - 0.00000000000000000000000000000000003324 142.0
HFD1_k127_4369168_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000002026 78.0
HFD1_k127_4369168_5 Methyltransferase domain - - - 0.0001109 46.0
HFD1_k127_438002_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 293.0
HFD1_k127_438002_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000001153 184.0
HFD1_k127_438002_2 Glucose / Sorbosone dehydrogenase K00428,K01728 - 1.11.1.5,4.2.2.2 0.0000000000000000000003508 113.0
HFD1_k127_4392965_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 332.0
HFD1_k127_4399625_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 538.0
HFD1_k127_4408229_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0 1147.0
HFD1_k127_4408229_1 Amidohydrolase family K06015 - 3.5.1.81 7.002e-217 687.0
HFD1_k127_4408229_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 450.0
HFD1_k127_4408229_11 threonine synthase activity K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 420.0
HFD1_k127_4408229_12 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 432.0
HFD1_k127_4408229_13 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 407.0
HFD1_k127_4408229_14 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 403.0
HFD1_k127_4408229_15 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 376.0
HFD1_k127_4408229_16 In Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 364.0
HFD1_k127_4408229_17 FRG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 346.0
HFD1_k127_4408229_18 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 290.0
HFD1_k127_4408229_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006608 280.0
HFD1_k127_4408229_2 SMART Elongator protein 3 MiaB NifB - - - 5.54e-214 678.0
HFD1_k127_4408229_20 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000005597 229.0
HFD1_k127_4408229_21 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000006526 216.0
HFD1_k127_4408229_22 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000003637 185.0
HFD1_k127_4408229_23 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000002074 182.0
HFD1_k127_4408229_24 TIGRFAM N-terminal double-transmembrane domain - - - 0.0000000000000000000000000000000000000001276 171.0
HFD1_k127_4408229_25 Protein of unknown function (DUF983) - - - 0.000000000000000001778 91.0
HFD1_k127_4408229_3 MacB-like periplasmic core domain - - - 5.354e-201 653.0
HFD1_k127_4408229_4 efflux transmembrane transporter activity K02004 - - 9.261e-199 646.0
HFD1_k127_4408229_5 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 581.0
HFD1_k127_4408229_6 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 529.0
HFD1_k127_4408229_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 470.0
HFD1_k127_4408229_8 Luciferase-like monooxygenase K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 446.0
HFD1_k127_4408229_9 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 432.0
HFD1_k127_4410675_0 Transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 383.0
HFD1_k127_4410675_1 - - - - 0.00000000000000000000005692 105.0
HFD1_k127_4420142_0 Penicillin amidase - - - 0.0 1064.0
HFD1_k127_4420142_1 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 422.0
HFD1_k127_4420142_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 364.0
HFD1_k127_4420142_3 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000002531 264.0
HFD1_k127_4420142_4 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002018 275.0
HFD1_k127_4420142_5 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000001844 214.0
HFD1_k127_4420142_6 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000008401 198.0
HFD1_k127_4420142_7 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000382 163.0
HFD1_k127_4420142_8 PFAM Transposase IS200 like K07491 - - 0.00001041 57.0
HFD1_k127_4459395_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 402.0
HFD1_k127_4459395_1 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 303.0
HFD1_k127_4459395_2 Penicillin-binding Protein K05364 - - 0.00000000000000000000000000000000000000000000000000004125 207.0
HFD1_k127_4459395_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000002979 173.0
HFD1_k127_4459395_4 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000761 124.0
HFD1_k127_4459395_5 Forkhead associated domain K03466 - - 0.000000003888 67.0
HFD1_k127_4467127_0 PBS lyase HEAT-like repeat - - - 6.169e-317 994.0
HFD1_k127_4467127_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 7.502e-223 711.0
HFD1_k127_4467127_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 496.0
HFD1_k127_4467127_3 Methyltransferase, chemotaxis proteins K00575,K13486 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 372.0
HFD1_k127_4467127_4 CheC inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000098 250.0
HFD1_k127_4467127_5 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000002561 188.0
HFD1_k127_4467127_6 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000004093 161.0
HFD1_k127_4467127_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000007459 153.0
HFD1_k127_4467127_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000002896 75.0
HFD1_k127_4468766_0 COG3666 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 481.0
HFD1_k127_4474626_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 548.0
HFD1_k127_4474626_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 356.0
HFD1_k127_4474626_2 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 348.0
HFD1_k127_4474626_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000005301 206.0
HFD1_k127_4474626_4 Transcriptional regulator, LysR family K21703 - - 0.00000000000000000000000000000000000361 149.0
HFD1_k127_4486659_0 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 452.0
HFD1_k127_4486659_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 372.0
HFD1_k127_4486659_2 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002896 285.0
HFD1_k127_4486659_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001076 255.0
HFD1_k127_4486659_4 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000001994 185.0
HFD1_k127_4501163_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 450.0
HFD1_k127_4501163_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 295.0
HFD1_k127_4501163_2 - - - - 0.0002799 46.0
HFD1_k127_4502852_0 protein adenylyltransferase activity - GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006952,GO:0007600,GO:0007601,GO:0007610,GO:0007632,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015696,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0023051,GO:0030176,GO:0030544,GO:0030554,GO:0031072,GO:0031224,GO:0031227,GO:0031967,GO:0031975,GO:0031984,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034260,GO:0034976,GO:0035639,GO:0036094,GO:0036211,GO:0042175,GO:0042578,GO:0042742,GO:0042802,GO:0042803,GO:0043086,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044601,GO:0044602,GO:0044603,GO:0045117,GO:0046983,GO:0048519,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050877,GO:0050896,GO:0050906,GO:0050908,GO:0050953,GO:0050962,GO:0051087,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051606,GO:0051608,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0065009,GO:0070566,GO:0070733,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:0098542,GO:0098827,GO:0140096,GO:1900101,GO:1901265,GO:1901363,GO:1901564,GO:1903894,GO:1905897 - 0.0000000000004596 79.0
HFD1_k127_4524643_0 Transposase DDE domain - - - 2.541e-204 639.0
HFD1_k127_4529452_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1056.0
HFD1_k127_4529452_1 ASPIC and UnbV - - - 9.449e-246 773.0
HFD1_k127_4529452_2 Alpha-L-fucosidase C-terminal domain - - - 3.883e-237 743.0
HFD1_k127_4529452_3 WD40-like Beta Propeller Repeat - - - 9.006e-234 732.0
HFD1_k127_4529452_4 Pfam Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 312.0
HFD1_k127_4529452_5 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000005323 216.0
HFD1_k127_4529452_6 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000000000000000001098 109.0
HFD1_k127_4532520_0 Sortilin, neurotensin receptor 3, - - - 0.0 1422.0
HFD1_k127_4532520_1 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1158.0
HFD1_k127_4532520_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 591.0
HFD1_k127_4532520_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 462.0
HFD1_k127_4532520_4 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 430.0
HFD1_k127_4532520_5 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001269 217.0
HFD1_k127_4532520_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000008359 196.0
HFD1_k127_4532520_7 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000004393 157.0
HFD1_k127_4532520_8 - - - - 0.000000000000000000000001148 108.0
HFD1_k127_4541244_0 PFAM Type II secretion system protein E K02652 - - 9.299e-214 677.0
HFD1_k127_4541244_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 538.0
HFD1_k127_4541244_10 ATPases associated with a variety of cellular activities K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 322.0
HFD1_k127_4541244_11 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001017 282.0
HFD1_k127_4541244_12 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002677 268.0
HFD1_k127_4541244_13 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007755 283.0
HFD1_k127_4541244_14 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009772 274.0
HFD1_k127_4541244_15 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004967 246.0
HFD1_k127_4541244_16 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000006087 242.0
HFD1_k127_4541244_17 Putative Ig domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008421 252.0
HFD1_k127_4541244_18 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000009637 238.0
HFD1_k127_4541244_19 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000002297 214.0
HFD1_k127_4541244_2 Replicative DNA helicase K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 488.0
HFD1_k127_4541244_20 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000458 199.0
HFD1_k127_4541244_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000002455 196.0
HFD1_k127_4541244_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000000000000000006279 214.0
HFD1_k127_4541244_23 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000008589 201.0
HFD1_k127_4541244_24 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000009623 195.0
HFD1_k127_4541244_25 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000001037 187.0
HFD1_k127_4541244_26 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000007628 181.0
HFD1_k127_4541244_27 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000002112 198.0
HFD1_k127_4541244_28 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000642 179.0
HFD1_k127_4541244_29 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000874 193.0
HFD1_k127_4541244_3 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 453.0
HFD1_k127_4541244_30 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000001106 175.0
HFD1_k127_4541244_31 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000001008 153.0
HFD1_k127_4541244_32 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000002105 149.0
HFD1_k127_4541244_33 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000002293 140.0
HFD1_k127_4541244_34 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000003593 136.0
HFD1_k127_4541244_35 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000004976 139.0
HFD1_k127_4541244_36 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.0000000000000000000000000000002413 136.0
HFD1_k127_4541244_37 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000003497 130.0
HFD1_k127_4541244_38 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000001546 115.0
HFD1_k127_4541244_39 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000001747 112.0
HFD1_k127_4541244_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 398.0
HFD1_k127_4541244_40 GtrA-like protein - - - 0.0000000000000000000000002155 111.0
HFD1_k127_4541244_41 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000002177 108.0
HFD1_k127_4541244_42 Polymer-forming cytoskeletal - - - 0.000000000000000002531 90.0
HFD1_k127_4541244_43 Tetratricopeptide repeat - - - 0.0000000001297 72.0
HFD1_k127_4541244_45 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.00000000229 65.0
HFD1_k127_4541244_47 Protein of unknown function (DUF465) - - - 0.00000002635 61.0
HFD1_k127_4541244_48 Pilus assembly protein - - - 0.000001543 59.0
HFD1_k127_4541244_5 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 398.0
HFD1_k127_4541244_50 general secretion pathway protein G K02456 - - 0.0003445 50.0
HFD1_k127_4541244_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 405.0
HFD1_k127_4541244_7 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 383.0
HFD1_k127_4541244_8 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 347.0
HFD1_k127_4541244_9 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 336.0
HFD1_k127_4571052_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000001253 151.0
HFD1_k127_4571052_1 Transglycosylase associated protein - - - 0.00000000001775 69.0
HFD1_k127_458023_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 389.0
HFD1_k127_458023_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000001555 130.0
HFD1_k127_458023_2 Ankyrin repeats (3 copies) - - - 0.0000001717 58.0
HFD1_k127_4612962_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000001244 132.0
HFD1_k127_462980_0 InterPro IPR001584 COGs COG2801 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 586.0
HFD1_k127_462980_1 Selenoprotein B glycine betaine sarcosine D-proline reductase K10672 - 1.21.4.2 0.000000000000000002196 86.0
HFD1_k127_469441_0 Carboxypeptidase regulatory-like domain - - - 4.771e-246 795.0
HFD1_k127_469441_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 480.0
HFD1_k127_469441_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000002697 228.0
HFD1_k127_469441_3 cell redox homeostasis - - - 0.00000000000000001685 87.0
HFD1_k127_474484_0 MgtE intracellular N domain K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 571.0
HFD1_k127_474484_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 524.0
HFD1_k127_474484_2 methyltransferase activity - - - 0.000000000000000000000000001303 115.0
HFD1_k127_474484_3 Amidohydrolase family - - - 0.000000000000006703 78.0
HFD1_k127_474484_4 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00002741 48.0
HFD1_k127_474484_5 Zn peptidase - - - 0.0006819 50.0
HFD1_k127_4795999_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.141e-216 702.0
HFD1_k127_4795999_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 499.0
HFD1_k127_4795999_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 402.0
HFD1_k127_4795999_3 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 316.0
HFD1_k127_4795999_4 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005847 291.0
HFD1_k127_4795999_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family K05928 - 2.1.1.95 0.00000000000000000000000000000000000000000000000000001438 203.0
HFD1_k127_4795999_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000004018 143.0
HFD1_k127_4795999_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000202 118.0
HFD1_k127_4795999_8 nuclear chromosome segregation - - - 0.00000000000000000008238 103.0
HFD1_k127_4795999_9 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00000000000001771 88.0
HFD1_k127_4809298_0 PFAM IS1 transposase K07480 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005581 280.0
HFD1_k127_481202_0 ASCH - - - 0.000000009729 57.0
HFD1_k127_481202_1 cAMP biosynthetic process - - - 0.00002698 52.0
HFD1_k127_4824742_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 438.0
HFD1_k127_4824742_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000006311 215.0
HFD1_k127_4824742_2 Hep Hag repeat protein K11904,K21449 - - 0.000000000000000000537 98.0
HFD1_k127_4824742_3 Hep Hag repeat protein K11904,K21449 - - 0.00000000000000001681 98.0
HFD1_k127_4824742_4 tail collar domain protein - - - 0.00000004939 67.0
HFD1_k127_4830698_0 - - - - 0.00000000000000000000000000000000009124 134.0
HFD1_k127_4830698_1 ORF located using Blastx - - - 0.000000000000000000000000004887 113.0
HFD1_k127_4830698_2 - - - - 0.00000005923 55.0
HFD1_k127_4830698_3 - - - - 0.0000001507 59.0
HFD1_k127_4835127_0 transduction histidine kinase - - - 0.00000000000000000000000000000000000000595 150.0
HFD1_k127_4839709_0 PFAM transposase mutator type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 416.0
HFD1_k127_4846991_0 - - - - 0.0000000000000000000000000000001798 126.0
HFD1_k127_4846991_1 - - - - 0.0000000000000000000000000000006329 124.0
HFD1_k127_4846991_2 - - - - 0.000000000000000000000009071 101.0
HFD1_k127_4846991_4 COG NOG14552 non supervised orthologous group - - - 0.000000000001853 66.0
HFD1_k127_4872712_0 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 407.0
HFD1_k127_4872712_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 366.0
HFD1_k127_4872712_2 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 333.0
HFD1_k127_4873804_0 PQQ enzyme repeat K00117 - 1.1.5.2 1.334e-320 996.0
HFD1_k127_4873804_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 366.0
HFD1_k127_4873804_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000006985 230.0
HFD1_k127_4873804_3 - - - - 0.0000000000000000000000000000000000000000000000000000000006443 215.0
HFD1_k127_4873804_4 -acetyltransferase - - - 0.00000000000000000000000000000000000000000001929 168.0
HFD1_k127_4882520_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000463 223.0
HFD1_k127_4882520_1 COGs COG3677 Transposase and inactivated derivatives K07480 - - 0.00000000000000000000000000000000000000000000000000000001967 205.0
HFD1_k127_4882520_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000001001 149.0
HFD1_k127_4882520_3 Nitrile hydratase beta subunit - - - 0.0000000000000000000000000000000000000011 150.0
HFD1_k127_4882520_4 Transposase DDE domain - - - 0.000000000000000000000000000000000000003235 150.0
HFD1_k127_4888750_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1371.0
HFD1_k127_4888750_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 9.208e-214 673.0
HFD1_k127_4888750_10 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 405.0
HFD1_k127_4888750_11 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 398.0
HFD1_k127_4888750_12 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 394.0
HFD1_k127_4888750_13 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 391.0
HFD1_k127_4888750_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 337.0
HFD1_k127_4888750_15 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 338.0
HFD1_k127_4888750_16 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 334.0
HFD1_k127_4888750_17 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 323.0
HFD1_k127_4888750_18 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 325.0
HFD1_k127_4888750_19 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 325.0
HFD1_k127_4888750_2 glutamine synthetase K01915 - 6.3.1.2 8.055e-205 646.0
HFD1_k127_4888750_20 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 288.0
HFD1_k127_4888750_21 Belongs to the PAPS reductase family. CysH subfamily K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000006652 266.0
HFD1_k127_4888750_22 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001177 266.0
HFD1_k127_4888750_23 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009591 261.0
HFD1_k127_4888750_24 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001023 267.0
HFD1_k127_4888750_25 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000001223 249.0
HFD1_k127_4888750_26 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000002655 246.0
HFD1_k127_4888750_27 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001102 238.0
HFD1_k127_4888750_28 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000007647 234.0
HFD1_k127_4888750_29 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000207 230.0
HFD1_k127_4888750_3 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 592.0
HFD1_k127_4888750_30 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000004357 216.0
HFD1_k127_4888750_31 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000004482 214.0
HFD1_k127_4888750_32 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000008495 207.0
HFD1_k127_4888750_33 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000001613 219.0
HFD1_k127_4888750_34 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000003497 209.0
HFD1_k127_4888750_35 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000009873 204.0
HFD1_k127_4888750_37 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000006592 153.0
HFD1_k127_4888750_38 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000000006278 147.0
HFD1_k127_4888750_39 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000009731 146.0
HFD1_k127_4888750_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 545.0
HFD1_k127_4888750_40 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000926 143.0
HFD1_k127_4888750_41 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.000000000000000000000000000007874 133.0
HFD1_k127_4888750_42 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000005137 123.0
HFD1_k127_4888750_43 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000001804 113.0
HFD1_k127_4888750_44 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000001521 108.0
HFD1_k127_4888750_45 Protein of unknown function (DUF2892) - - - 0.000000000000000000001403 96.0
HFD1_k127_4888750_46 cheY-homologous receiver domain K22010 - - 0.000000000000000003151 94.0
HFD1_k127_4888750_47 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000007805 91.0
HFD1_k127_4888750_5 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 503.0
HFD1_k127_4888750_6 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 499.0
HFD1_k127_4888750_7 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366 - 1.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 483.0
HFD1_k127_4888750_8 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 467.0
HFD1_k127_4888750_9 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 486.0
HFD1_k127_4890121_0 HemY domain protein - - - 0.00000000000000000000005919 111.0
HFD1_k127_4890121_1 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000183 59.0
HFD1_k127_4894687_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0 1097.0
HFD1_k127_4894687_1 TonB-dependent receptor - - - 1.967e-260 839.0
HFD1_k127_4894687_10 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 391.0
HFD1_k127_4894687_11 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 387.0
HFD1_k127_4894687_12 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 385.0
HFD1_k127_4894687_13 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 376.0
HFD1_k127_4894687_14 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 369.0
HFD1_k127_4894687_15 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 355.0
HFD1_k127_4894687_16 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 359.0
HFD1_k127_4894687_17 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 339.0
HFD1_k127_4894687_18 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 331.0
HFD1_k127_4894687_19 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 319.0
HFD1_k127_4894687_2 TonB-dependent receptor - - - 4.905e-212 699.0
HFD1_k127_4894687_20 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 314.0
HFD1_k127_4894687_21 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 340.0
HFD1_k127_4894687_22 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 302.0
HFD1_k127_4894687_23 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 297.0
HFD1_k127_4894687_24 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 290.0
HFD1_k127_4894687_25 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000512 290.0
HFD1_k127_4894687_26 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000007797 269.0
HFD1_k127_4894687_27 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001724 260.0
HFD1_k127_4894687_28 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000542 272.0
HFD1_k127_4894687_29 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000001688 239.0
HFD1_k127_4894687_3 amino acid transport K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 510.0
HFD1_k127_4894687_30 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000004213 219.0
HFD1_k127_4894687_31 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.0000000000000000000000000000000000000000000000000000000000881 224.0
HFD1_k127_4894687_32 helix_turn_helix, mercury resistance K22491 - - 0.00000000000000000000000000000000000000000000000002661 191.0
HFD1_k127_4894687_33 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000002345 172.0
HFD1_k127_4894687_34 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000004896 168.0
HFD1_k127_4894687_35 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000005139 166.0
HFD1_k127_4894687_36 YhhN family - - - 0.00000000000000000000000000000000000000001492 162.0
HFD1_k127_4894687_37 TonB-dependent receptor - - - 0.00000000000000000000000000000000000001989 159.0
HFD1_k127_4894687_38 MFS transporter - - - 0.00000000000000000000000000000009659 138.0
HFD1_k127_4894687_39 PFAM Cyclic nucleotide-binding K10914 - - 0.000000000000000000000000002863 121.0
HFD1_k127_4894687_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 503.0
HFD1_k127_4894687_40 - - - - 0.0000000000000002757 89.0
HFD1_k127_4894687_41 Cupredoxin-like domain - - - 0.0000000000000005936 91.0
HFD1_k127_4894687_42 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000004538 82.0
HFD1_k127_4894687_43 Reeler domain - - - 0.000000000000008989 85.0
HFD1_k127_4894687_44 peptidyl-tyrosine sulfation - - - 0.0000000000826 70.0
HFD1_k127_4894687_45 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000008854 70.0
HFD1_k127_4894687_46 Prokaryotic N-terminal methylation motif K02650 - - 0.00000001949 63.0
HFD1_k127_4894687_47 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000002986 61.0
HFD1_k127_4894687_49 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0007022 50.0
HFD1_k127_4894687_5 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 476.0
HFD1_k127_4894687_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 444.0
HFD1_k127_4894687_7 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 426.0
HFD1_k127_4894687_8 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 412.0
HFD1_k127_4894687_9 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 411.0
HFD1_k127_4905179_0 Reverse transcriptase K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 314.0
HFD1_k127_4912002_0 Tricorn protease homolog K08676 - - 0.0 1553.0
HFD1_k127_4912002_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.555e-239 750.0
HFD1_k127_4912002_10 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 373.0
HFD1_k127_4912002_11 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 366.0
HFD1_k127_4912002_12 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 351.0
HFD1_k127_4912002_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 331.0
HFD1_k127_4912002_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 318.0
HFD1_k127_4912002_15 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 336.0
HFD1_k127_4912002_16 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 318.0
HFD1_k127_4912002_17 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 310.0
HFD1_k127_4912002_18 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 295.0
HFD1_k127_4912002_19 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 287.0
HFD1_k127_4912002_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 610.0
HFD1_k127_4912002_20 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002469 287.0
HFD1_k127_4912002_21 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008675 271.0
HFD1_k127_4912002_22 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
HFD1_k127_4912002_23 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000005713 253.0
HFD1_k127_4912002_24 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004303 244.0
HFD1_k127_4912002_25 COGs COG2912 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000004689 241.0
HFD1_k127_4912002_26 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000001402 209.0
HFD1_k127_4912002_27 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000007172 211.0
HFD1_k127_4912002_28 Putative esterase - - - 0.00000000000000000000000000000000000000000000000001429 192.0
HFD1_k127_4912002_29 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000001294 174.0
HFD1_k127_4912002_3 PFAM Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 580.0
HFD1_k127_4912002_30 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000003127 160.0
HFD1_k127_4912002_31 Trm112p-like protein K09791 - - 0.000000000000000000000005576 102.0
HFD1_k127_4912002_32 reductase K00059 - 1.1.1.100 0.0000000000000000000000336 109.0
HFD1_k127_4912002_33 Caspase domain - - - 0.000000000000000000008195 108.0
HFD1_k127_4912002_34 Phosphocarrier protein HPr K08485,K11189 - - 0.00000000000000000000896 94.0
HFD1_k127_4912002_35 - - - - 0.00000000000000000009862 103.0
HFD1_k127_4912002_36 Polymer-forming cytoskeletal - - - 0.0000000000000000004082 93.0
HFD1_k127_4912002_37 Methyltransferase small domain - - - 0.000000000000001489 86.0
HFD1_k127_4912002_38 PFAM glutaredoxin K18917 - 1.20.4.3 0.0000000005178 66.0
HFD1_k127_4912002_39 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000002005 59.0
HFD1_k127_4912002_4 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 580.0
HFD1_k127_4912002_40 - - - - 0.000000561 59.0
HFD1_k127_4912002_41 TIGRFAM TonB K03832 - - 0.00000128 60.0
HFD1_k127_4912002_42 Domain of unknown function (DUF4190) - - - 0.0004662 49.0
HFD1_k127_4912002_43 Tetratricopeptide repeat - - - 0.0005938 52.0
HFD1_k127_4912002_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 522.0
HFD1_k127_4912002_6 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 446.0
HFD1_k127_4912002_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 435.0
HFD1_k127_4912002_8 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 425.0
HFD1_k127_4912002_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 376.0
HFD1_k127_4913417_0 class II (D K K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 603.0
HFD1_k127_4913417_1 RQC K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 493.0
HFD1_k127_4913417_10 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000000002415 73.0
HFD1_k127_4913417_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 432.0
HFD1_k127_4913417_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 402.0
HFD1_k127_4913417_4 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 361.0
HFD1_k127_4913417_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001306 263.0
HFD1_k127_4913417_6 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000007275 225.0
HFD1_k127_4913417_7 LysM domain K08307,K12204 - - 0.000000000000000000000000000000000000000001488 171.0
HFD1_k127_4913417_8 oxidoreductase activity - - - 0.0000000000000000000000000000000001043 151.0
HFD1_k127_4913417_9 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000027 126.0
HFD1_k127_4922644_0 AcrB/AcrD/AcrF family - - - 0.0 1454.0
HFD1_k127_4922644_1 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 472.0
HFD1_k127_4933639_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003232 252.0
HFD1_k127_4933639_1 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000001558 214.0
HFD1_k127_4933639_2 DDE_Tnp_1-associated - - - 0.000000000000000000000000000000000004698 143.0
HFD1_k127_4933639_3 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000000000000000034 116.0
HFD1_k127_4933639_4 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000004058 108.0
HFD1_k127_4950371_0 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002681 281.0
HFD1_k127_4950371_1 methyltransferase - - - 0.00000000000000000000000000522 118.0
HFD1_k127_4950371_2 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000335 67.0
HFD1_k127_4950371_3 Glycosyl transferases group 1 - - - 0.000007822 48.0
HFD1_k127_495142_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 390.0
HFD1_k127_495142_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 335.0
HFD1_k127_495142_2 sequence-specific DNA binding K18830 - - 0.000001247 56.0
HFD1_k127_4956851_0 - - - - 0.0000000000000000000000000000000445 136.0
HFD1_k127_4956851_1 lytic transglycosylase activity - - - 0.0000006038 58.0
HFD1_k127_4956851_2 translation initiation factor activity - - - 0.00003168 57.0
HFD1_k127_4956851_3 - - - - 0.0004774 53.0
HFD1_k127_4979293_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.862e-316 990.0
HFD1_k127_4979293_1 Amidohydrolase family K01464 - 3.5.2.2 4.911e-208 655.0
HFD1_k127_4979293_10 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000001431 224.0
HFD1_k127_4979293_11 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000004388 188.0
HFD1_k127_4979293_12 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000004918 185.0
HFD1_k127_4979293_13 Protein involved in hydrolase activity K06889 - - 0.00000000000000000000000000000000001411 150.0
HFD1_k127_4979293_14 HEAT repeat - - - 0.00000000000001607 85.0
HFD1_k127_4979293_15 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.000001464 51.0
HFD1_k127_4979293_16 Domain of unknown function (DUF4440) - - - 0.0006535 49.0
HFD1_k127_4979293_2 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 582.0
HFD1_k127_4979293_3 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 507.0
HFD1_k127_4979293_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 447.0
HFD1_k127_4979293_5 Protein of unknown function (DUF3089) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 447.0
HFD1_k127_4979293_6 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 449.0
HFD1_k127_4979293_7 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 437.0
HFD1_k127_4979293_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 409.0
HFD1_k127_4992306_0 Psort location Cytoplasmic, score 7.50 - - - 0.0 1146.0
HFD1_k127_5002643_0 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000001946 101.0
HFD1_k127_5007501_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 321.0
HFD1_k127_5019751_0 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 386.0
HFD1_k127_5019751_1 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000000000000000001769 173.0
HFD1_k127_5020437_0 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000000000000000000000000000000000000000000000000000003722 213.0
HFD1_k127_5020437_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000002246 147.0
HFD1_k127_5020437_2 Transposase - - - 0.000000000000000000000000000000000001052 145.0
HFD1_k127_5023326_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 344.0
HFD1_k127_5023326_1 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000001256 222.0
HFD1_k127_5023326_2 SnoaL-like polyketide cyclase - - - 0.00000000000000001773 82.0
HFD1_k127_5025403_0 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.000000000000000000000000000000000000000000000000001252 191.0
HFD1_k127_5025403_1 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000000001206 157.0
HFD1_k127_5042684_0 transposition, RNA-mediated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 298.0
HFD1_k127_5043095_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000385 65.0
HFD1_k127_5043095_3 glyoxalase III activity - - - 0.0003061 43.0
HFD1_k127_5068238_0 C-terminus of AA_permease K03294 - - 1.692e-224 706.0
HFD1_k127_5068238_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 610.0
HFD1_k127_5068238_10 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000001129 229.0
HFD1_k127_5068238_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000007217 177.0
HFD1_k127_5068238_13 PFAM sugar transferase - - - 0.000000000000000000000000000000000000005249 146.0
HFD1_k127_5068238_14 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000001232 113.0
HFD1_k127_5068238_15 AAA ATPase domain - - - 0.0000000000000000003533 103.0
HFD1_k127_5068238_16 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - - 0.000000000000000004983 94.0
HFD1_k127_5068238_17 Protein of unknown function (DUF2752) - - - 0.0000000003117 68.0
HFD1_k127_5068238_18 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000008698 55.0
HFD1_k127_5068238_19 Recombinase zinc beta ribbon domain - - - 0.0003865 49.0
HFD1_k127_5068238_2 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 595.0
HFD1_k127_5068238_3 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 561.0
HFD1_k127_5068238_4 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 367.0
HFD1_k127_5068238_5 DNA polymerase III subunits gamma and tau domain III K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 339.0
HFD1_k127_5068238_6 histone H2A K63-linked ubiquitination K00998,K06131 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002978 286.0
HFD1_k127_5068238_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003961 273.0
HFD1_k127_5068238_8 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 258.0
HFD1_k127_5068238_9 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000002046 249.0
HFD1_k127_5068294_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 436.0
HFD1_k127_5068294_1 Amino acid adenylation domain - - - 0.000000000000001917 77.0
HFD1_k127_5071038_0 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001425 226.0
HFD1_k127_5071038_1 - - - - 0.00000000000000000000000000000000000000000004425 179.0
HFD1_k127_5071038_2 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000000000000000000000000000000009675 149.0
HFD1_k127_5071038_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000004843 59.0
HFD1_k127_5077290_0 Ribonuclease H protein - - - 4.437e-254 817.0
HFD1_k127_508560_0 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000007605 125.0
HFD1_k127_5095385_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 470.0
HFD1_k127_5095385_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 463.0
HFD1_k127_5095385_10 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002677 273.0
HFD1_k127_5095385_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002975 263.0
HFD1_k127_5095385_12 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000002594 258.0
HFD1_k127_5095385_13 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003437 243.0
HFD1_k127_5095385_14 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000001128 162.0
HFD1_k127_5095385_15 diguanylate cyclase - - - 0.0000000000000000000000000000000000000001021 175.0
HFD1_k127_5095385_16 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000133 154.0
HFD1_k127_5095385_17 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000000000000000003251 134.0
HFD1_k127_5095385_18 HD domain - - - 0.00000000000000000000000001083 127.0
HFD1_k127_5095385_19 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000008078 112.0
HFD1_k127_5095385_2 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 477.0
HFD1_k127_5095385_20 Receptor family ligand binding region K01999 - - 0.000000000000000000000001916 122.0
HFD1_k127_5095385_21 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000005458 98.0
HFD1_k127_5095385_22 Fe2 transport system protein A K04758 - - 0.0000000001746 66.0
HFD1_k127_5095385_23 - - - - 0.000000001483 69.0
HFD1_k127_5095385_24 Tetratricopeptide repeat - - - 0.000002114 62.0
HFD1_k127_5095385_25 Quinol cytochrome c oxidoreductase membrane protein - - - 0.0009685 48.0
HFD1_k127_5095385_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 458.0
HFD1_k127_5095385_4 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 466.0
HFD1_k127_5095385_5 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 357.0
HFD1_k127_5095385_6 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 330.0
HFD1_k127_5095385_7 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 314.0
HFD1_k127_5095385_8 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 311.0
HFD1_k127_5095385_9 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 303.0
HFD1_k127_5101945_0 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001059 236.0
HFD1_k127_5101945_1 Transposase - - - 0.000000000000000000000000001305 117.0
HFD1_k127_5101945_2 PFAM Integrase catalytic region - - - 0.00000000000000000000002233 101.0
HFD1_k127_5101945_3 Integrase core domain - - - 0.00000000115 60.0
HFD1_k127_5101945_4 Elements of external origin K07497 - - 0.00004266 50.0
HFD1_k127_5108121_0 K02A2.6-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 442.0
HFD1_k127_5117218_0 protein kinase activity - - - 0.000000000000000000000000000000113 128.0
HFD1_k127_5117218_1 Winged helix-turn helix - - - 0.00000000000000000000008069 105.0
HFD1_k127_5117218_2 DDE superfamily endonuclease - - - 0.00000000002237 69.0
HFD1_k127_5118567_0 hmm pf02371 K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 341.0
HFD1_k127_5118567_1 PFAM Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000006519 177.0
HFD1_k127_5118567_2 PFAM Transposase - - - 0.00000000000000000000000000000000000007259 142.0
HFD1_k127_5147115_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 538.0
HFD1_k127_5147115_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 359.0
HFD1_k127_5147115_2 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004096 261.0
HFD1_k127_514894_0 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 400.0
HFD1_k127_514894_1 response to abiotic stimulus K03086,K06867 - - 0.000000000001497 76.0
HFD1_k127_5150352_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 363.0
HFD1_k127_5159542_0 Peptidase M14, carboxypeptidase A - - - 0.0 1118.0
HFD1_k127_5159542_1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 7.92e-207 657.0
HFD1_k127_5159542_10 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 409.0
HFD1_k127_5159542_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 413.0
HFD1_k127_5159542_12 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 410.0
HFD1_k127_5159542_13 Ethanolamine ammonia-lyase light chain (EutC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 414.0
HFD1_k127_5159542_14 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 384.0
HFD1_k127_5159542_15 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 375.0
HFD1_k127_5159542_16 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 373.0
HFD1_k127_5159542_17 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 346.0
HFD1_k127_5159542_18 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 342.0
HFD1_k127_5159542_19 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 334.0
HFD1_k127_5159542_2 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 605.0
HFD1_k127_5159542_20 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 321.0
HFD1_k127_5159542_21 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 307.0
HFD1_k127_5159542_22 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 298.0
HFD1_k127_5159542_23 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 302.0
HFD1_k127_5159542_24 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002647 272.0
HFD1_k127_5159542_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002394 284.0
HFD1_k127_5159542_26 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000002744 222.0
HFD1_k127_5159542_27 methyltransferase K04786 - - 0.0000000000000000000000000000000000000000000000000000000001339 213.0
HFD1_k127_5159542_28 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000007429 207.0
HFD1_k127_5159542_29 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000005321 201.0
HFD1_k127_5159542_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 574.0
HFD1_k127_5159542_30 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000223 185.0
HFD1_k127_5159542_31 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000003396 192.0
HFD1_k127_5159542_32 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000004951 167.0
HFD1_k127_5159542_33 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000001281 170.0
HFD1_k127_5159542_34 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000008297 148.0
HFD1_k127_5159542_35 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000001623 139.0
HFD1_k127_5159542_36 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000009334 137.0
HFD1_k127_5159542_37 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000001013 135.0
HFD1_k127_5159542_38 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000001946 123.0
HFD1_k127_5159542_39 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000003515 115.0
HFD1_k127_5159542_4 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 582.0
HFD1_k127_5159542_40 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000000000000003265 109.0
HFD1_k127_5159542_41 response regulator receiver K03407 - 2.7.13.3 0.000000000000000000004498 98.0
HFD1_k127_5159542_42 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000001464 89.0
HFD1_k127_5159542_43 Belongs to the peptidase S1C family K04771,K04772,K08070 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0031224,GO:0031226,GO:0031233,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051603,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 1.3.1.74,3.4.21.107 0.00000000000002683 86.0
HFD1_k127_5159542_44 Domain of unknown function (DUF4149) - - - 0.0000000000002796 77.0
HFD1_k127_5159542_45 peptidase M15B and M15C DD-carboxypeptidase VanY - - - 0.0000000000005395 79.0
HFD1_k127_5159542_46 - - - - 0.00000007131 65.0
HFD1_k127_5159542_5 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 576.0
HFD1_k127_5159542_6 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K01710,K02377 - 1.1.1.271,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 544.0
HFD1_k127_5159542_7 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 482.0
HFD1_k127_5159542_8 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 446.0
HFD1_k127_5159542_9 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 409.0
HFD1_k127_5175574_0 cellulose binding - - - 0.0 1156.0
HFD1_k127_5175574_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 599.0
HFD1_k127_5175574_10 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000001209 83.0
HFD1_k127_5175574_11 sodium proton antiporter K03316 - - 0.000000000006256 69.0
HFD1_k127_5175574_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 370.0
HFD1_k127_5175574_3 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 321.0
HFD1_k127_5175574_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001146 244.0
HFD1_k127_5175574_5 -O-antigen - - - 0.000000000000000000000000000000000000000000000000001953 199.0
HFD1_k127_5175574_6 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000002272 141.0
HFD1_k127_5175574_7 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.00000000000000000000000000000349 132.0
HFD1_k127_5175574_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000007269 115.0
HFD1_k127_5175574_9 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000406 83.0
HFD1_k127_5190013_0 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 326.0
HFD1_k127_5190013_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000005572 263.0
HFD1_k127_5190013_2 Sodium Bile acid symporter family - - - 0.00000000000000000000000000004846 127.0
HFD1_k127_51906_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 3.271e-315 983.0
HFD1_k127_51906_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000017 244.0
HFD1_k127_51906_10 Protein of unknown function (DUF2958) - - - 0.00001965 48.0
HFD1_k127_51906_2 Cation transport regulator - - - 0.000000000000000000000000000000000000000000000000000000000000006252 221.0
HFD1_k127_51906_3 Prolyl oligopeptidase, N-terminal beta-propeller domain - - - 0.0000000000000000000000000000000000000000001131 166.0
HFD1_k127_51906_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000007007 169.0
HFD1_k127_51906_5 domain, Protein - - - 0.0000000000000000000000000001558 132.0
HFD1_k127_51906_6 Hep Hag repeat protein K11904,K21449 - - 0.000000000000000002609 99.0
HFD1_k127_51906_7 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000008189 74.0
HFD1_k127_51906_8 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000002099 53.0
HFD1_k127_5192901_0 CHASE3 domain - - - 5.903e-240 758.0
HFD1_k127_5192901_1 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 446.0
HFD1_k127_5192901_10 FG-GAP repeat - - - 0.0000000002006 76.0
HFD1_k127_5192901_2 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 304.0
HFD1_k127_5192901_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 303.0
HFD1_k127_5192901_4 COG2931 RTX toxins and related Ca2 -binding - - - 0.000000000000000000000000000000000000000000000000000000000001143 241.0
HFD1_k127_5192901_5 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000003173 201.0
HFD1_k127_5192901_6 Universal stress protein family - - - 0.00000000000000000000000000000000000000001471 166.0
HFD1_k127_5192901_7 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.00000000000000000000000000000000003725 157.0
HFD1_k127_5192901_8 AMP binding K06149 - - 0.00000000000000000000000004938 115.0
HFD1_k127_5192901_9 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000001406 103.0
HFD1_k127_5204674_0 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 424.0
HFD1_k127_5204674_1 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000009533 236.0
HFD1_k127_5204674_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 0.000000000000000000000000000000000000000000000005649 174.0
HFD1_k127_5204674_3 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000002634 170.0
HFD1_k127_5234101_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.434e-295 926.0
HFD1_k127_5234101_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 3.327e-238 766.0
HFD1_k127_5234101_10 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003005 259.0
HFD1_k127_5234101_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000001202 262.0
HFD1_k127_5234101_12 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000001495 262.0
HFD1_k127_5234101_13 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
HFD1_k127_5234101_14 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003605 250.0
HFD1_k127_5234101_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001669 252.0
HFD1_k127_5234101_16 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000004462 223.0
HFD1_k127_5234101_17 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000000000000000000002593 145.0
HFD1_k127_5234101_18 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000183 110.0
HFD1_k127_5234101_19 - - - - 0.00000000000000000000001383 102.0
HFD1_k127_5234101_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 593.0
HFD1_k127_5234101_20 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000007235 93.0
HFD1_k127_5234101_21 Domain of unknown function (DUF1844) - - - 0.000000000007128 73.0
HFD1_k127_5234101_22 Type II secretion system (T2SS), protein G K02456 - - 0.0000000001227 70.0
HFD1_k127_5234101_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 341.0
HFD1_k127_5234101_4 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 323.0
HFD1_k127_5234101_5 Belongs to the ATCase OTCase family K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 322.0
HFD1_k127_5234101_6 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 303.0
HFD1_k127_5234101_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000637 284.0
HFD1_k127_5234101_8 Mo-molybdopterin cofactor biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001204 280.0
HFD1_k127_5234101_9 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000193 275.0
HFD1_k127_5240844_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 508.0
HFD1_k127_5240844_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 385.0
HFD1_k127_5240844_2 PFAM Short-chain dehydrogenase reductase SDR K00059,K00076 - 1.1.1.100,1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001567 274.0
HFD1_k127_5240844_3 response to heat K03695,K03696,K03697,K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001084 271.0
HFD1_k127_5240844_4 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000000000002545 113.0
HFD1_k127_5240844_5 - - - - 0.00000000000000000000000002834 112.0
HFD1_k127_5240844_6 E1-E2 ATPase K01531 - 3.6.3.2 0.000000000001088 70.0
HFD1_k127_5240844_7 Belongs to the 'phage' integrase family - - - 0.0000001315 59.0
HFD1_k127_5246723_0 - - - - 0.000000000000000000000000000000001969 132.0
HFD1_k127_5246723_1 - - - - 0.0000000000000000000001867 100.0
HFD1_k127_5246723_4 ATP synthase K02132 - - 0.00005332 45.0
HFD1_k127_5253898_0 Trehalose utilisation K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 435.0
HFD1_k127_5253898_1 Trehalose utilisation K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 415.0
HFD1_k127_5253898_2 Trehalose utilisation K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 400.0
HFD1_k127_5253898_3 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000004184 252.0
HFD1_k127_5253898_4 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002058 242.0
HFD1_k127_5253898_5 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000794 164.0
HFD1_k127_5275223_0 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 539.0
HFD1_k127_5275223_1 Soluble NSF attachment protein, SNAP - - - 0.00000000000001948 77.0
HFD1_k127_5285172_0 - - - - 0.0000000000000000000000000000000001989 132.0
HFD1_k127_5285172_1 - - - - 0.0000000000000000000000000000005829 124.0
HFD1_k127_5285172_2 - - - - 0.000000000000000000000001025 103.0
HFD1_k127_5285172_3 - - - - 0.0000000000000000000004834 96.0
HFD1_k127_5285172_4 - - - - 0.00000000000000000003086 90.0
HFD1_k127_5294112_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 6.296e-270 854.0
HFD1_k127_5294112_1 Domain of unknown function (DUF5117) - - - 1.41e-252 805.0
HFD1_k127_5294112_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000001595 205.0
HFD1_k127_5294112_11 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000004353 194.0
HFD1_k127_5294112_12 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000009408 184.0
HFD1_k127_5294112_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000002246 154.0
HFD1_k127_5294112_14 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000001936 130.0
HFD1_k127_5294112_15 - - - - 0.00000000000000000000000000000002745 131.0
HFD1_k127_5294112_16 acetyltransferase - - - 0.000000000000000000000000000000133 138.0
HFD1_k127_5294112_17 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000511 100.0
HFD1_k127_5294112_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 608.0
HFD1_k127_5294112_3 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 593.0
HFD1_k127_5294112_4 N-4 methylation of cytosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 447.0
HFD1_k127_5294112_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 407.0
HFD1_k127_5294112_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 388.0
HFD1_k127_5294112_7 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 381.0
HFD1_k127_5294112_8 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 316.0
HFD1_k127_5294112_9 - - - - 0.000000000000000000000000000000000000000000000000000000005248 214.0
HFD1_k127_5306995_0 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002934 261.0
HFD1_k127_5306995_1 Patatin-like phospholipase K07001 - - 0.0000000000000000007257 98.0
HFD1_k127_5306995_2 TOBE domain K02010,K02052 - 3.6.3.30 0.000000000000000004367 87.0
HFD1_k127_5306995_3 N-6 DNA Methylase - - - 0.000007168 48.0
HFD1_k127_5306995_4 - - - - 0.0003248 47.0
HFD1_k127_5309830_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 324.0
HFD1_k127_5352337_0 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 400.0
HFD1_k127_5352337_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000008377 73.0
HFD1_k127_5354376_0 PFAM Transposase - - - 0.0000000000000000000000000000000000000000231 166.0
HFD1_k127_5366486_0 Domain of unknown function (DUF4277) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 565.0
HFD1_k127_5366486_1 Psort location Cytoplasmic, score 8.96 - - - 0.00000008285 55.0
HFD1_k127_5439523_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 443.0
HFD1_k127_54766_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 316.0
HFD1_k127_54766_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000002906 106.0
HFD1_k127_553223_0 Sodium:solute symporter family - - - 7.208e-250 784.0
HFD1_k127_553223_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 614.0
HFD1_k127_553223_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 426.0
HFD1_k127_553223_11 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 415.0
HFD1_k127_553223_12 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 368.0
HFD1_k127_553223_13 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 370.0
HFD1_k127_553223_14 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 357.0
HFD1_k127_553223_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 331.0
HFD1_k127_553223_16 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 307.0
HFD1_k127_553223_17 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 295.0
HFD1_k127_553223_18 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002572 255.0
HFD1_k127_553223_19 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001131 264.0
HFD1_k127_553223_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 580.0
HFD1_k127_553223_20 modulates the activities of several proteins which are inactive in their K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000003081 240.0
HFD1_k127_553223_21 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000003758 236.0
HFD1_k127_553223_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000065 216.0
HFD1_k127_553223_23 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000005836 189.0
HFD1_k127_553223_24 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000001372 185.0
HFD1_k127_553223_25 - - - - 0.0000000000000000000000000000000000000001263 153.0
HFD1_k127_553223_26 diguanylate cyclase - - - 0.000000000000000000000000000000000000000221 169.0
HFD1_k127_553223_28 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000002821 139.0
HFD1_k127_553223_29 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000271 121.0
HFD1_k127_553223_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 492.0
HFD1_k127_553223_30 Bacterial DNA-binding protein K03530 - - 0.0000000000000000000000003438 111.0
HFD1_k127_553223_31 phosphorelay signal transduction system K02488,K04757 - 2.7.11.1,2.7.7.65 0.0000000000000000000000007452 111.0
HFD1_k127_553223_32 LUD domain K18929 - - 0.0000000000001476 73.0
HFD1_k127_553223_33 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000002023 81.0
HFD1_k127_553223_35 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000001038 65.0
HFD1_k127_553223_36 - - - - 0.000000003505 66.0
HFD1_k127_553223_38 Belongs to the ompA family - - - 0.0000007392 59.0
HFD1_k127_553223_39 AntiSigma factor - - - 0.000004788 57.0
HFD1_k127_553223_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 454.0
HFD1_k127_553223_40 - - - - 0.00008374 51.0
HFD1_k127_553223_41 Domain of unknown function (DUF4440) - - - 0.0001442 49.0
HFD1_k127_553223_5 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 449.0
HFD1_k127_553223_6 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 443.0
HFD1_k127_553223_7 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 443.0
HFD1_k127_553223_8 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 436.0
HFD1_k127_553223_9 carboxylic ester hydrolase activity K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 426.0
HFD1_k127_5589017_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 538.0
HFD1_k127_5589017_1 Nucleotidyltransferase domain - - - 0.000000000000000000000000000004425 121.0
HFD1_k127_5628754_0 Dehydrogenase K00117 - 1.1.5.2 1.962e-307 957.0
HFD1_k127_5628754_1 GMC oxidoreductase - - - 3.06e-235 739.0
HFD1_k127_5628754_10 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000002473 147.0
HFD1_k127_5628754_11 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000000000000000000000000000002653 148.0
HFD1_k127_5628754_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 556.0
HFD1_k127_5628754_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 425.0
HFD1_k127_5628754_4 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 398.0
HFD1_k127_5628754_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 315.0
HFD1_k127_5628754_6 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000001864 212.0
HFD1_k127_5628754_7 - - - - 0.000000000000000000000000000000000000000000000000000001096 196.0
HFD1_k127_5628754_8 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000005134 184.0
HFD1_k127_5628754_9 Cytochrome c - - - 0.0000000000000000000000000000000000001379 149.0
HFD1_k127_5632675_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 412.0
HFD1_k127_5632675_1 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 294.0
HFD1_k127_5632675_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000007703 174.0
HFD1_k127_5632675_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000003254 96.0
HFD1_k127_5632675_5 Helix-turn-helix domain - - - 0.00000006154 56.0
HFD1_k127_5640627_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 405.0
HFD1_k127_5640627_1 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000002693 150.0
HFD1_k127_5640627_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.0000000000001351 73.0
HFD1_k127_5640627_3 AhpC TSA family - - - 0.000000006635 61.0
HFD1_k127_5640627_4 Redoxin - - - 0.00000002929 58.0
HFD1_k127_5640627_5 Protein of unknown function (DUF2889) - - - 0.000001946 57.0
HFD1_k127_5642287_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000001406 151.0
HFD1_k127_5642419_0 Phosphate acyltransferases K01897 - 6.2.1.3 6.57e-257 818.0
HFD1_k127_5642419_1 SMART Elongator protein 3 MiaB NifB - - - 1.956e-231 752.0
HFD1_k127_5642419_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 377.0
HFD1_k127_5642419_11 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 374.0
HFD1_k127_5642419_12 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 385.0
HFD1_k127_5642419_13 PFAM Helix-turn-helix, type 11 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 353.0
HFD1_k127_5642419_14 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 331.0
HFD1_k127_5642419_15 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 305.0
HFD1_k127_5642419_16 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 298.0
HFD1_k127_5642419_17 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 302.0
HFD1_k127_5642419_18 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 321.0
HFD1_k127_5642419_19 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003175 265.0
HFD1_k127_5642419_2 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 606.0
HFD1_k127_5642419_20 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
HFD1_k127_5642419_21 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000002102 248.0
HFD1_k127_5642419_22 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000001504 250.0
HFD1_k127_5642419_23 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002074 250.0
HFD1_k127_5642419_24 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000001117 241.0
HFD1_k127_5642419_25 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000001133 219.0
HFD1_k127_5642419_26 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000001934 212.0
HFD1_k127_5642419_27 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000008284 183.0
HFD1_k127_5642419_28 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000000000000000000000000000006108 181.0
HFD1_k127_5642419_29 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000008615 178.0
HFD1_k127_5642419_3 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 524.0
HFD1_k127_5642419_30 transcriptional regulator containing an HTH domain and an K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000006617 176.0
HFD1_k127_5642419_31 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.0000000000000000000000000000000000000001089 154.0
HFD1_k127_5642419_32 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000002964 154.0
HFD1_k127_5642419_33 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000008396 152.0
HFD1_k127_5642419_34 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000001029 133.0
HFD1_k127_5642419_35 ribosomal large subunit export from nucleus - - - 0.000000000000000000000001568 109.0
HFD1_k127_5642419_36 lysyltransferase activity K07027 - - 0.0000000000000000001101 101.0
HFD1_k127_5642419_37 Competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.00000000001654 68.0
HFD1_k127_5642419_38 shape-determining protein MreD K03571 - - 0.0000000004903 67.0
HFD1_k127_5642419_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 512.0
HFD1_k127_5642419_40 Outer membrane lipoprotein K05807,K08309 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000003199 62.0
HFD1_k127_5642419_41 Putative peptidoglycan binding domain - - - 0.00000003262 63.0
HFD1_k127_5642419_42 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000008848 59.0
HFD1_k127_5642419_43 - - - - 0.000003249 55.0
HFD1_k127_5642419_44 - - - - 0.00003653 54.0
HFD1_k127_5642419_5 Ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 539.0
HFD1_k127_5642419_6 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 496.0
HFD1_k127_5642419_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 485.0
HFD1_k127_5642419_8 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 461.0
HFD1_k127_5642419_9 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 392.0
HFD1_k127_5652049_1 - - - - 0.00000000000000000008103 91.0
HFD1_k127_5652049_2 COG NOG15344 non supervised orthologous group - - - 0.00000000000000001697 82.0
HFD1_k127_5659547_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 511.0
HFD1_k127_5659547_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000001228 233.0
HFD1_k127_5659547_2 electron transfer activity - - - 0.00000000000000000000000000000000128 143.0
HFD1_k127_5659547_4 - - - - 0.000000000005369 71.0
HFD1_k127_5659547_5 PIN domain - - - 0.00000934 48.0
HFD1_k127_5660958_0 - - - - 0.0000000000000000000000000000000000000000000003872 184.0
HFD1_k127_5669923_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 5e-324 1011.0
HFD1_k127_5669923_1 iron-nicotianamine transmembrane transporter activity - - - 2.774e-287 905.0
HFD1_k127_5669923_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 308.0
HFD1_k127_5669923_11 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 299.0
HFD1_k127_5669923_12 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 306.0
HFD1_k127_5669923_13 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007269 279.0
HFD1_k127_5669923_14 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001141 283.0
HFD1_k127_5669923_15 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007048 282.0
HFD1_k127_5669923_16 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000001103 255.0
HFD1_k127_5669923_17 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000001969 248.0
HFD1_k127_5669923_18 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001288 221.0
HFD1_k127_5669923_19 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000458 199.0
HFD1_k127_5669923_2 Domain of unknown function (DUF3536) - - - 4.024e-238 761.0
HFD1_k127_5669923_20 RDD family - - - 0.00000000000000000000000000000000000000000000002006 180.0
HFD1_k127_5669923_21 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000003129 169.0
HFD1_k127_5669923_22 WHG domain - - - 0.000000000000000000000000000000000000000001889 164.0
HFD1_k127_5669923_23 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000000000000000000000007692 145.0
HFD1_k127_5669923_24 positive regulation of translation, ncRNA-mediated K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000000002371 106.0
HFD1_k127_5669923_25 Reeler domain - - - 0.00000000000000002224 94.0
HFD1_k127_5669923_26 Beta-lactamase - - - 0.0000000000006311 71.0
HFD1_k127_5669923_27 Transcription factor zinc-finger K09981 - - 0.00000000009707 66.0
HFD1_k127_5669923_28 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000417 51.0
HFD1_k127_5669923_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 2.629e-225 711.0
HFD1_k127_5669923_4 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 575.0
HFD1_k127_5669923_5 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 496.0
HFD1_k127_5669923_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 434.0
HFD1_k127_5669923_7 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 425.0
HFD1_k127_5669923_8 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 411.0
HFD1_k127_5669923_9 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 312.0
HFD1_k127_5677803_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.542e-227 713.0
HFD1_k127_5677803_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 602.0
HFD1_k127_5677803_2 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 364.0
HFD1_k127_5677803_3 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 349.0
HFD1_k127_5677803_4 BON domain - - - 0.00000000000000000000000000000000000000000000002967 177.0
HFD1_k127_5677803_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000007483 64.0
HFD1_k127_5677803_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000002624 57.0
HFD1_k127_5678374_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000146 177.0
HFD1_k127_5680695_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 469.0
HFD1_k127_5680695_1 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 437.0
HFD1_k127_5680695_2 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 323.0
HFD1_k127_5680695_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
HFD1_k127_5680695_4 Protein of unknown function (DUF454) K09790 - - 0.0000000000000277 82.0
HFD1_k127_5682846_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 600.0
HFD1_k127_5682846_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 498.0
HFD1_k127_5682846_2 Phage plasmid primase, P4 K06919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 301.0
HFD1_k127_5682846_3 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000000001054 200.0
HFD1_k127_5682846_4 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000004316 146.0
HFD1_k127_5682846_5 - - - - 0.00000000000000000000001375 108.0
HFD1_k127_5682846_6 Belongs to the 'phage' integrase family - - - 0.000000000000000008985 92.0
HFD1_k127_5682846_7 TPR Domain containing protein K12600 - - 0.00000000000000041 90.0
HFD1_k127_5682846_8 D5 N terminal like - - - 0.0001063 47.0
HFD1_k127_5695859_0 O-antigen - - - 0.00000000000000000001602 108.0
HFD1_k127_5695859_1 ABC transporter K06147,K11085 - - 0.000000000000000001054 86.0
HFD1_k127_5695859_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000001371 92.0
HFD1_k127_5695859_3 ABC transporter transmembrane region K11085 - - 0.00000000000728 66.0
HFD1_k127_5695861_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 601.0
HFD1_k127_5695861_1 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 281.0
HFD1_k127_5695861_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000009166 57.0
HFD1_k127_5695861_11 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00002336 54.0
HFD1_k127_5695861_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001296 289.0
HFD1_k127_5695861_3 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000002089 160.0
HFD1_k127_5695861_4 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000004752 130.0
HFD1_k127_5695861_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000043 130.0
HFD1_k127_5695861_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000001505 118.0
HFD1_k127_5695861_7 ABC-type multidrug transport system ATPase and permease K06147,K11085 - - 0.000000000000000001448 86.0
HFD1_k127_5695861_9 protein secretion K03116 - - 0.0000000001276 64.0
HFD1_k127_5700998_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.293e-205 650.0
HFD1_k127_5700998_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 606.0
HFD1_k127_5700998_10 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000001092 239.0
HFD1_k127_5700998_11 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000003614 217.0
HFD1_k127_5700998_12 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000002032 210.0
HFD1_k127_5700998_13 - - - - 0.00000000000000000000000000000000000000000000000000001093 192.0
HFD1_k127_5700998_14 lipid kinase, YegS Rv2252 BmrU family - - - 0.00000000000000000000000000000000000000000000000000001982 201.0
HFD1_k127_5700998_15 thiolester hydrolase activity K07000 - - 0.0000000000000000000000000000000000000000000007115 175.0
HFD1_k127_5700998_16 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000007589 182.0
HFD1_k127_5700998_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000242 153.0
HFD1_k127_5700998_19 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000002271 118.0
HFD1_k127_5700998_2 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 587.0
HFD1_k127_5700998_20 methyltransferase - - - 0.00000000000000000000000000002516 127.0
HFD1_k127_5700998_21 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - 0.00000000000000000000000000006084 121.0
HFD1_k127_5700998_22 DinB family - - - 0.00000000000000000000000003023 116.0
HFD1_k127_5700998_23 DinB family - - - 0.00000000000000002572 88.0
HFD1_k127_5700998_24 Beta-lactamase - - - 0.0000000000000006574 85.0
HFD1_k127_5700998_25 - - - - 0.0000101 58.0
HFD1_k127_5700998_26 Transposase - - - 0.0001746 48.0
HFD1_k127_5700998_3 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 356.0
HFD1_k127_5700998_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 336.0
HFD1_k127_5700998_5 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 322.0
HFD1_k127_5700998_6 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006721 283.0
HFD1_k127_5700998_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003855 280.0
HFD1_k127_5700998_8 Pfam Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001571 270.0
HFD1_k127_5700998_9 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004294 266.0
HFD1_k127_5708015_0 radical SAM domain protein - - - 6.402e-240 749.0
HFD1_k127_5708015_1 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 619.0
HFD1_k127_5708015_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003105 275.0
HFD1_k127_5708015_11 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000009606 241.0
HFD1_k127_5708015_12 PQQ enzyme repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001927 244.0
HFD1_k127_5708015_13 PFAM peptidylprolyl isomerase FKBP-type K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000009596 160.0
HFD1_k127_5708015_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000007103 166.0
HFD1_k127_5708015_15 HAD-superfamily hydrolase, subfamily IA K01091,K06019 - 3.1.3.18,3.6.1.1 0.0000000000000000000000000000000000000002733 157.0
HFD1_k127_5708015_16 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000006937 140.0
HFD1_k127_5708015_17 von Willebrand factor, type A - - - 0.0000000000000000000000000000000005266 145.0
HFD1_k127_5708015_18 phosphoserine phosphatase activity K04757 - 2.7.11.1 0.00000000000000000000003391 103.0
HFD1_k127_5708015_19 Response regulator, receiver K06147 - - 0.00000000000000008444 86.0
HFD1_k127_5708015_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 497.0
HFD1_k127_5708015_20 PFAM Forkhead-associated protein - - - 0.0000000000000118 83.0
HFD1_k127_5708015_21 TIGRFAM TonB family C-terminal domain K03832 - - 0.0000000000005929 78.0
HFD1_k127_5708015_22 Belongs to the 5'-nucleotidase family - - - 0.0000001063 63.0
HFD1_k127_5708015_23 - K03686 - - 0.0000003441 56.0
HFD1_k127_5708015_24 TPR repeat-containing protein K07452 - - 0.00004676 55.0
HFD1_k127_5708015_3 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 454.0
HFD1_k127_5708015_4 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 345.0
HFD1_k127_5708015_5 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 314.0
HFD1_k127_5708015_6 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 321.0
HFD1_k127_5708015_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 303.0
HFD1_k127_5708015_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003926 301.0
HFD1_k127_5708015_9 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001193 273.0
HFD1_k127_5715516_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008965 459.0
HFD1_k127_5715516_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 356.0
HFD1_k127_5718216_0 Ribosomal protein S1 K02945 - - 5.366e-205 656.0
HFD1_k127_5718216_1 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 439.0
HFD1_k127_5718216_2 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005737 265.0
HFD1_k127_5718216_3 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002006 272.0
HFD1_k127_5718216_4 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000009574 202.0
HFD1_k127_5718216_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000006834 180.0
HFD1_k127_5718216_6 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000005111 145.0
HFD1_k127_5718216_7 Beta-lactamase class C - - - 0.0000000000000000004013 89.0
HFD1_k127_5719422_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 497.0
HFD1_k127_5719422_1 ECF sigma factor - - - 0.000000000000000000000000000000004443 131.0
HFD1_k127_5719422_2 serine threonine protein kinase - - - 0.000000000000000000216 91.0
HFD1_k127_5719422_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000001112 69.0
HFD1_k127_5719422_4 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.00000001245 58.0
HFD1_k127_5720827_0 Carboxypeptidase regulatory-like domain - - - 1.063e-268 861.0
HFD1_k127_5720827_1 Trehalase K01194 - 3.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 617.0
HFD1_k127_57419_0 FtsX-like permease family - - - 1.729e-250 798.0
HFD1_k127_57419_1 efflux transmembrane transporter activity K02004 - - 2.072e-212 686.0
HFD1_k127_57419_2 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 335.0
HFD1_k127_57419_3 protein conserved in bacteria K09990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 284.0
HFD1_k127_57419_4 Rhodanese Homology Domain - - - 0.000000000000000000001686 99.0
HFD1_k127_57419_5 - - - - 0.000000000000000000009283 93.0
HFD1_k127_5744964_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.274e-309 965.0
HFD1_k127_5744964_1 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 4.296e-206 647.0
HFD1_k127_5744964_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000009536 262.0
HFD1_k127_5744964_11 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000276 235.0
HFD1_k127_5744964_12 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000001808 233.0
HFD1_k127_5744964_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000005952 209.0
HFD1_k127_5744964_14 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000007807 192.0
HFD1_k127_5744964_15 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000004803 177.0
HFD1_k127_5744964_16 - - - - 0.00000000000000000000000000000000000000006517 156.0
HFD1_k127_5744964_17 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000000000000000001133 148.0
HFD1_k127_5744964_18 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000000000006312 119.0
HFD1_k127_5744964_19 chlorophyll binding - - - 0.000000000000000000000001083 112.0
HFD1_k127_5744964_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 597.0
HFD1_k127_5744964_20 Chorismate mutase type II K04093 - 5.4.99.5 0.00000000000000000008651 94.0
HFD1_k127_5744964_21 - - - - 0.000000000000002815 79.0
HFD1_k127_5744964_22 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000003705 79.0
HFD1_k127_5744964_23 - - - - 0.0000000194 59.0
HFD1_k127_5744964_24 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00008807 55.0
HFD1_k127_5744964_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 574.0
HFD1_k127_5744964_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 506.0
HFD1_k127_5744964_5 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 468.0
HFD1_k127_5744964_6 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 466.0
HFD1_k127_5744964_7 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 372.0
HFD1_k127_5744964_8 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 321.0
HFD1_k127_5744964_9 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001885 274.0
HFD1_k127_5756664_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1110.0
HFD1_k127_5756664_1 helicase activity - - - 0.0 1035.0
HFD1_k127_5756664_10 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 562.0
HFD1_k127_5756664_101 Domain of unknown function (DUF4388) - - - 0.00007967 53.0
HFD1_k127_5756664_102 Belongs to the AAA ATPase family K03798 - - 0.0003351 51.0
HFD1_k127_5756664_103 YjbR - - - 0.0005702 50.0
HFD1_k127_5756664_11 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 565.0
HFD1_k127_5756664_12 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 560.0
HFD1_k127_5756664_13 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 549.0
HFD1_k127_5756664_14 COG0471 Di- and tricarboxylate transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 551.0
HFD1_k127_5756664_15 succinyl-diaminopimelate desuccinylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 531.0
HFD1_k127_5756664_16 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 527.0
HFD1_k127_5756664_17 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 543.0
HFD1_k127_5756664_18 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 535.0
HFD1_k127_5756664_19 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 485.0
HFD1_k127_5756664_2 radical SAM domain protein - - - 4.28e-285 886.0
HFD1_k127_5756664_20 cystathionine gamma-synthase activity K01758,K01760,K01761 - 4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 486.0
HFD1_k127_5756664_21 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 484.0
HFD1_k127_5756664_22 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 473.0
HFD1_k127_5756664_23 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 473.0
HFD1_k127_5756664_24 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 473.0
HFD1_k127_5756664_25 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 475.0
HFD1_k127_5756664_26 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 458.0
HFD1_k127_5756664_27 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 442.0
HFD1_k127_5756664_28 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 421.0
HFD1_k127_5756664_29 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 417.0
HFD1_k127_5756664_3 Urocanase Rossmann-like domain K01712 - 4.2.1.49 7.185e-278 865.0
HFD1_k127_5756664_30 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 419.0
HFD1_k127_5756664_31 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 414.0
HFD1_k127_5756664_32 amine oxidase K00276 - 1.4.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 414.0
HFD1_k127_5756664_33 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 396.0
HFD1_k127_5756664_34 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 406.0
HFD1_k127_5756664_35 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 367.0
HFD1_k127_5756664_36 Major intrinsic protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 365.0
HFD1_k127_5756664_37 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 378.0
HFD1_k127_5756664_38 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 382.0
HFD1_k127_5756664_39 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 336.0
HFD1_k127_5756664_4 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 1.616e-247 778.0
HFD1_k127_5756664_40 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 324.0
HFD1_k127_5756664_41 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 317.0
HFD1_k127_5756664_42 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 314.0
HFD1_k127_5756664_43 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 298.0
HFD1_k127_5756664_44 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 301.0
HFD1_k127_5756664_45 surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 315.0
HFD1_k127_5756664_46 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 290.0
HFD1_k127_5756664_47 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001231 286.0
HFD1_k127_5756664_48 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 279.0
HFD1_k127_5756664_49 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001964 276.0
HFD1_k127_5756664_5 Zinc carboxypeptidase - - - 5.417e-208 680.0
HFD1_k127_5756664_50 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008917 281.0
HFD1_k127_5756664_51 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006673 268.0
HFD1_k127_5756664_52 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001041 261.0
HFD1_k127_5756664_53 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000001327 258.0
HFD1_k127_5756664_54 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000002934 261.0
HFD1_k127_5756664_55 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002225 255.0
HFD1_k127_5756664_56 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000003129 250.0
HFD1_k127_5756664_57 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000001929 224.0
HFD1_k127_5756664_58 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000003936 218.0
HFD1_k127_5756664_59 sugar phosphate isomerase involved in capsule formation K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000001759 216.0
HFD1_k127_5756664_6 Peptidase family M28 - - - 1.082e-206 662.0
HFD1_k127_5756664_60 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000001366 210.0
HFD1_k127_5756664_61 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000006255 219.0
HFD1_k127_5756664_62 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000006446 226.0
HFD1_k127_5756664_63 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000006765 202.0
HFD1_k127_5756664_64 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000007271 198.0
HFD1_k127_5756664_65 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000001129 198.0
HFD1_k127_5756664_66 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000001946 189.0
HFD1_k127_5756664_67 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000002411 187.0
HFD1_k127_5756664_68 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000003837 193.0
HFD1_k127_5756664_69 YjbR - - - 0.000000000000000000000000000000000000000000000003765 177.0
HFD1_k127_5756664_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.026e-202 642.0
HFD1_k127_5756664_70 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000008202 181.0
HFD1_k127_5756664_71 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000002523 160.0
HFD1_k127_5756664_72 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000001876 145.0
HFD1_k127_5756664_73 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000002246 149.0
HFD1_k127_5756664_74 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000008232 138.0
HFD1_k127_5756664_75 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000004404 126.0
HFD1_k127_5756664_76 RNA recognition motif - - - 0.0000000000000000000000000006076 116.0
HFD1_k127_5756664_77 Hfq protein - - - 0.0000000000000000000000000133 113.0
HFD1_k127_5756664_78 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000008546 109.0
HFD1_k127_5756664_79 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000001535 121.0
HFD1_k127_5756664_8 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 595.0
HFD1_k127_5756664_80 NUDIX domain K08310 - 3.6.1.67 0.000000000000000000000001731 108.0
HFD1_k127_5756664_81 YceI-like domain - - - 0.00000000000000000000002101 109.0
HFD1_k127_5756664_82 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000004594 115.0
HFD1_k127_5756664_83 Dodecin K09165 - - 0.00000000000000000000016 99.0
HFD1_k127_5756664_84 - - - - 0.000000000000000000003039 98.0
HFD1_k127_5756664_85 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000001163 105.0
HFD1_k127_5756664_86 Lysin motif - - - 0.00000000000000000008694 95.0
HFD1_k127_5756664_87 Putative phosphatase (DUF442) - - - 0.0000000000000000003965 94.0
HFD1_k127_5756664_89 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000006226 87.0
HFD1_k127_5756664_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 575.0
HFD1_k127_5756664_90 Transcriptional regulator K07506 - - 0.0000000000000002233 85.0
HFD1_k127_5756664_91 Tetratricopeptide repeat - - - 0.000000000000001932 86.0
HFD1_k127_5756664_92 Carboxypeptidase regulatory-like domain - - - 0.00000000000001571 85.0
HFD1_k127_5756664_93 integral membrane protein - - - 0.00000000000006856 82.0
HFD1_k127_5756664_94 Outer membrane lipoprotein-sorting protein - - - 0.000000000003754 77.0
HFD1_k127_5756664_95 NUDIX domain - - - 0.0000000001018 69.0
HFD1_k127_5756664_96 - - - - 0.00000000013 63.0
HFD1_k127_5756664_97 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0000000001613 71.0
HFD1_k127_5756664_98 Outer membrane protein (OmpH-like) K06142 - - 0.000000003721 66.0
HFD1_k127_5756664_99 Outer membrane protein (OmpH-like) K06142 - - 0.000005564 56.0
HFD1_k127_5758081_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.0 1025.0
HFD1_k127_5758081_1 serine-type peptidase activity K01278 - 3.4.14.5 1.5e-323 1004.0
HFD1_k127_5758081_10 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000001932 113.0
HFD1_k127_5758081_11 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000077 80.0
HFD1_k127_5758081_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000006645 83.0
HFD1_k127_5758081_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 3.364e-298 929.0
HFD1_k127_5758081_3 outer membrane efflux protein - - - 5.611e-198 629.0
HFD1_k127_5758081_4 Transport permease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 559.0
HFD1_k127_5758081_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 528.0
HFD1_k127_5758081_6 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 510.0
HFD1_k127_5758081_7 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 412.0
HFD1_k127_5758081_8 Carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 376.0
HFD1_k127_5758081_9 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 352.0
HFD1_k127_5766846_0 Sortilin, neurotensin receptor 3, - - - 0.0 1475.0
HFD1_k127_5766846_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1134.0
HFD1_k127_5766846_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000005063 266.0
HFD1_k127_5766846_11 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000001893 255.0
HFD1_k127_5766846_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008149 259.0
HFD1_k127_5766846_13 COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002022 238.0
HFD1_k127_5766846_14 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000003139 237.0
HFD1_k127_5766846_15 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000008695 243.0
HFD1_k127_5766846_16 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000138 229.0
HFD1_k127_5766846_17 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000003641 215.0
HFD1_k127_5766846_18 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000008203 178.0
HFD1_k127_5766846_19 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000002745 178.0
HFD1_k127_5766846_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.376e-279 869.0
HFD1_k127_5766846_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000008635 166.0
HFD1_k127_5766846_21 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000004816 153.0
HFD1_k127_5766846_22 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000003666 152.0
HFD1_k127_5766846_23 PFAM TfoX N-terminal domain K07343 - - 0.0000000000000000000000000000003572 130.0
HFD1_k127_5766846_24 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000004277 120.0
HFD1_k127_5766846_25 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000308 106.0
HFD1_k127_5766846_26 - - - - 0.000000000000000000000004696 108.0
HFD1_k127_5766846_27 SNARE associated Golgi protein - - - 0.00000000000000000000003184 108.0
HFD1_k127_5766846_28 PIN domain - - - 0.0000000000000000000008259 100.0
HFD1_k127_5766846_29 energy transducer activity K03832 - - 0.0000000000000001682 89.0
HFD1_k127_5766846_3 Tetratricopeptide repeats K12132 - 2.7.11.1 8.525e-196 635.0
HFD1_k127_5766846_30 Putative zinc-finger - GO:0005575,GO:0016020 - 0.0000003405 61.0
HFD1_k127_5766846_31 gag-polyprotein putative aspartyl protease - - - 0.0000006818 62.0
HFD1_k127_5766846_32 Tetratricopeptide repeat protein - - - 0.00001352 56.0
HFD1_k127_5766846_33 - - - - 0.00007813 49.0
HFD1_k127_5766846_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 616.0
HFD1_k127_5766846_5 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 520.0
HFD1_k127_5766846_6 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 496.0
HFD1_k127_5766846_7 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 435.0
HFD1_k127_5766846_8 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 344.0
HFD1_k127_5766846_9 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 331.0
HFD1_k127_5767441_0 Sulfate permease family - - - 4.122e-240 757.0
HFD1_k127_5767441_1 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 451.0
HFD1_k127_5767441_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 457.0
HFD1_k127_5767441_3 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 331.0
HFD1_k127_5767441_5 CHAD - - - 0.0000000000000000000000000000000000000000007798 169.0
HFD1_k127_5767441_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000003207 136.0
HFD1_k127_5767441_7 Ion transport 2 domain protein - - - 0.00000000000000000000000000005172 124.0
HFD1_k127_5767441_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000003512 70.0
HFD1_k127_5767441_9 Belongs to the glycosyl hydrolase 13 family - - - 0.00000002807 57.0
HFD1_k127_5771683_0 Histidine kinase - - - 0.0 1652.0
HFD1_k127_5771683_1 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 569.0
HFD1_k127_5771683_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 347.0
HFD1_k127_5771683_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 320.0
HFD1_k127_5771683_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000002724 240.0
HFD1_k127_5771683_5 Transposase K07491 - - 0.0000000000000000000000000000000000000000000003165 173.0
HFD1_k127_5771683_6 metallopeptidase activity K08738,K20276 - - 0.00000000000000000000000000006566 134.0
HFD1_k127_5771683_7 - - - - 0.0000000002075 70.0
HFD1_k127_5771683_9 Transposase IS200 like K07491 - - 0.00004567 47.0
HFD1_k127_5794830_0 K02A2.6-like - - - 0.0000000000000000000000000000000000000000000000000000000000000002238 232.0
HFD1_k127_5795921_0 Belongs to the metal hydrolase YfiT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001331 233.0
HFD1_k127_5795921_1 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.0000000000000000000000000000000000005831 143.0
HFD1_k127_57977_0 transport - - - 0.0 1201.0
HFD1_k127_57977_1 Carboxypeptidase regulatory-like domain - - - 0.0 1031.0
HFD1_k127_57977_2 beta-lactamase - - - 9.921e-261 830.0
HFD1_k127_57977_3 IgA Peptidase M64 - - - 1.778e-210 667.0
HFD1_k127_57977_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.942e-197 637.0
HFD1_k127_57977_5 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 541.0
HFD1_k127_57977_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 441.0
HFD1_k127_57977_7 BadF BadG BcrA BcrD K00884,K02616 - 2.7.1.59 0.000000000000000000000000000000000000000008419 167.0
HFD1_k127_57977_8 SIS domain K00820 - 2.6.1.16 0.00000000000000000000000000000000000312 151.0
HFD1_k127_57977_9 DNA topological change - - - 0.00000001081 57.0
HFD1_k127_5802912_0 metallocarboxypeptidase activity K14054 - - 0.0 1229.0
HFD1_k127_5802912_1 metallocarboxypeptidase activity K14054 - - 8.764e-283 900.0
HFD1_k127_5802912_10 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000002318 183.0
HFD1_k127_5802912_11 - - - - 0.0000000000000000000000000000000000004175 152.0
HFD1_k127_5802912_12 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000002071 113.0
HFD1_k127_5802912_13 Periplasmic copper-binding protein (NosD) - - - 0.000000003305 68.0
HFD1_k127_5802912_14 - - - - 0.0000000114 68.0
HFD1_k127_5802912_2 PQQ-like domain K05889 - 1.1.2.6 1.289e-252 793.0
HFD1_k127_5802912_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 566.0
HFD1_k127_5802912_4 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 511.0
HFD1_k127_5802912_5 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 291.0
HFD1_k127_5802912_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006075 273.0
HFD1_k127_5802912_7 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000004613 252.0
HFD1_k127_5802912_8 fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000004143 220.0
HFD1_k127_5802912_9 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000001454 207.0
HFD1_k127_5803433_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 1.787e-268 843.0
HFD1_k127_5803433_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 2.202e-212 664.0
HFD1_k127_5803433_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 495.0
HFD1_k127_5803433_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 477.0
HFD1_k127_5803433_4 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000005179 189.0
HFD1_k127_5803433_5 Haem-binding domain - - - 0.0000000000000000000000000000005156 129.0
HFD1_k127_5803433_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000003928 66.0
HFD1_k127_5844945_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 345.0
HFD1_k127_5848752_0 - - - - 0.0000000000000000000000000000000000000000000000000000000463 200.0
HFD1_k127_5848752_1 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000007086 162.0
HFD1_k127_5848752_10 ORF located using Blastx - - - 0.000002213 55.0
HFD1_k127_5848752_2 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000000000002716 111.0
HFD1_k127_5848752_3 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000008999 92.0
HFD1_k127_5848752_4 - - - - 0.000000000000000008994 82.0
HFD1_k127_5848752_5 - - - - 0.00000000000002002 74.0
HFD1_k127_5848752_6 - - - - 0.000000000000421 70.0
HFD1_k127_5848752_8 - - - - 0.00000000002528 64.0
HFD1_k127_5858964_0 PFAM Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 504.0
HFD1_k127_5861508_0 ABC transporter K06020 - 3.6.3.25 1.163e-301 934.0
HFD1_k127_5861508_1 PFAM peptidase - - - 1.51e-222 703.0
HFD1_k127_5861508_10 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 365.0
HFD1_k127_5861508_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 359.0
HFD1_k127_5861508_12 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001006 282.0
HFD1_k127_5861508_13 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006594 269.0
HFD1_k127_5861508_14 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000002863 220.0
HFD1_k127_5861508_15 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000000006487 206.0
HFD1_k127_5861508_16 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000002473 215.0
HFD1_k127_5861508_17 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000000000002782 160.0
HFD1_k127_5861508_18 DinB superfamily - - - 0.00000000000000000000000000000000000000121 152.0
HFD1_k127_5861508_19 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.000000000000000000000000000000000000002103 161.0
HFD1_k127_5861508_2 (ABC) transporter K06147,K06148 - - 6.621e-213 678.0
HFD1_k127_5861508_20 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000859 156.0
HFD1_k127_5861508_22 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool K06019 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 0.000000000000000000000000001112 123.0
HFD1_k127_5861508_23 SpoVT / AbrB like domain K07172 - - 0.00000000000000000000000487 103.0
HFD1_k127_5861508_24 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000001024 112.0
HFD1_k127_5861508_25 SnoaL-like domain - - - 0.000000000000000003824 91.0
HFD1_k127_5861508_26 pilus organization K02674,K07004 - - 0.000000000001529 78.0
HFD1_k127_5861508_27 Leucine rich repeat variant - - - 0.00000000123 66.0
HFD1_k127_5861508_28 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000001965 59.0
HFD1_k127_5861508_29 PQQ-like domain - - - 0.0001089 49.0
HFD1_k127_5861508_3 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 1.106e-209 662.0
HFD1_k127_5861508_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 541.0
HFD1_k127_5861508_5 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 493.0
HFD1_k127_5861508_6 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 456.0
HFD1_k127_5861508_7 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 436.0
HFD1_k127_5861508_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 426.0
HFD1_k127_5861508_9 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 416.0
HFD1_k127_586159_0 protein phosphatase regulator activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001455 289.0
HFD1_k127_5872246_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 366.0
HFD1_k127_5878060_0 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001722 282.0
HFD1_k127_5878060_1 Major facilitator Superfamily K08222 - - 0.000000000000000000000000000002461 122.0
HFD1_k127_5880736_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 392.0
HFD1_k127_5901073_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 518.0
HFD1_k127_5904424_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005516 271.0
HFD1_k127_5904424_1 - - - - 0.0001663 48.0
HFD1_k127_5910314_0 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003407 230.0
HFD1_k127_5910314_1 Transposase - - - 0.00000000000000000000000000000000000000006802 156.0
HFD1_k127_5910314_2 DNA methylase K07316 - 2.1.1.72 0.000000000000000000000000000002019 120.0
HFD1_k127_593116_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001592 257.0
HFD1_k127_5938377_0 the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - 0.000000000000000000000003377 107.0
HFD1_k127_5938377_2 - - - - 0.00000000008102 63.0
HFD1_k127_5951335_0 Radical SAM - - - 0.0 1212.0
HFD1_k127_5951335_1 (ABC) transporter K06147,K18890 - - 5.506e-202 646.0
HFD1_k127_5951335_10 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 366.0
HFD1_k127_5951335_11 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 363.0
HFD1_k127_5951335_12 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 358.0
HFD1_k127_5951335_13 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 330.0
HFD1_k127_5951335_14 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 321.0
HFD1_k127_5951335_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004102 269.0
HFD1_k127_5951335_16 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001575 235.0
HFD1_k127_5951335_17 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000002866 219.0
HFD1_k127_5951335_18 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000001463 216.0
HFD1_k127_5951335_19 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000002124 186.0
HFD1_k127_5951335_2 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 592.0
HFD1_k127_5951335_20 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000002758 175.0
HFD1_k127_5951335_21 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000003894 125.0
HFD1_k127_5951335_22 ATPase or kinase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000001904 119.0
HFD1_k127_5951335_23 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000004146 117.0
HFD1_k127_5951335_24 SCO1/SenC - - - 0.000000000000000000000000005052 122.0
HFD1_k127_5951335_25 Domain of unknown function (DUF4442) K02614 - - 0.000000000000000000000001495 110.0
HFD1_k127_5951335_26 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.0000000000000000000002766 104.0
HFD1_k127_5951335_27 DinB family - - - 0.0000000000002869 76.0
HFD1_k127_5951335_28 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000551 79.0
HFD1_k127_5951335_29 transcriptional regulator, SARP family - - - 0.000008018 58.0
HFD1_k127_5951335_30 Sporulation related domain K03749 - - 0.00002858 55.0
HFD1_k127_5951335_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 487.0
HFD1_k127_5951335_5 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 478.0
HFD1_k127_5951335_6 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 470.0
HFD1_k127_5951335_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 446.0
HFD1_k127_5951335_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 392.0
HFD1_k127_5951335_9 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 393.0
HFD1_k127_6001666_0 transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000009917 231.0
HFD1_k127_6036202_0 PFAM GCN5-related N-acetyltransferase K03824 - - 0.00000000000000000000000000000000000000000000000001378 189.0
HFD1_k127_6036202_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000173 47.0
HFD1_k127_6038863_0 Tricorn protease homolog - - - 0.0 1401.0
HFD1_k127_6038863_1 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 395.0
HFD1_k127_6038863_2 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
HFD1_k127_6038863_3 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 292.0
HFD1_k127_6038863_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000001043 194.0
HFD1_k127_6038863_5 - - - - 0.000000000000000000000000000000000000000000004089 168.0
HFD1_k127_6038863_6 membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000000002808 160.0
HFD1_k127_6038863_7 Lysin motif - - - 0.00000000000000000000000000000000000006144 147.0
HFD1_k127_6038863_8 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000001315 132.0
HFD1_k127_6038863_9 PFAM Response regulator receiver domain K11521 - - 0.000006764 51.0
HFD1_k127_6040790_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 536.0
HFD1_k127_6048080_0 Belongs to the peptidase M16 family K07263 - - 0.0 1135.0
HFD1_k127_6048080_1 transport - - - 1.631e-300 959.0
HFD1_k127_6048080_10 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 323.0
HFD1_k127_6048080_11 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000001051 287.0
HFD1_k127_6048080_12 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009271 244.0
HFD1_k127_6048080_13 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000001035 256.0
HFD1_k127_6048080_14 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000000000000000000000000000000000000000000000001109 246.0
HFD1_k127_6048080_15 competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004442 235.0
HFD1_k127_6048080_16 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000004548 234.0
HFD1_k127_6048080_17 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007639 234.0
HFD1_k127_6048080_18 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000001502 230.0
HFD1_k127_6048080_19 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000004723 223.0
HFD1_k127_6048080_2 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 625.0
HFD1_k127_6048080_20 - - - - 0.000000000000000000000000000000000000000000000000000000003232 201.0
HFD1_k127_6048080_21 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000001136 213.0
HFD1_k127_6048080_22 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000006459 198.0
HFD1_k127_6048080_23 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000005422 188.0
HFD1_k127_6048080_24 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000001462 192.0
HFD1_k127_6048080_25 nitrite reductase [NAD(P)H] activity - - - 0.000000000000000000000000000000000000000000000001592 194.0
HFD1_k127_6048080_26 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000001339 173.0
HFD1_k127_6048080_27 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000002998 144.0
HFD1_k127_6048080_28 Domain of unknown function (DUF4350) - - - 0.00000000000000000000000000005497 129.0
HFD1_k127_6048080_29 protein conserved in bacteria K04750 - - 0.0000000000000000000000000001977 120.0
HFD1_k127_6048080_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 442.0
HFD1_k127_6048080_30 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000008212 113.0
HFD1_k127_6048080_31 Domain of unknown function (DUF4440) - - - 0.00000000000000000136 90.0
HFD1_k127_6048080_32 peptidoglycan binding K02453,K03749 GO:0000910,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0030428,GO:0032153,GO:0032506,GO:0042834,GO:0044464,GO:0051301,GO:0097367 - 0.00004861 51.0
HFD1_k127_6048080_4 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 411.0
HFD1_k127_6048080_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 407.0
HFD1_k127_6048080_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 394.0
HFD1_k127_6048080_7 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 367.0
HFD1_k127_6048080_8 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 344.0
HFD1_k127_6048080_9 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 332.0
HFD1_k127_6059005_0 Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002744 262.0
HFD1_k127_6059005_1 PFAM Transposase IS66 family K07484 - - 0.0000000000000000000001415 106.0
HFD1_k127_6098013_0 SMART PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 366.0
HFD1_k127_6098013_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 343.0
HFD1_k127_6098013_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000007678 101.0
HFD1_k127_6111486_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005691 243.0
HFD1_k127_6111486_1 recombinase activity - - - 0.0000000000000000000000000000000000000002267 153.0
HFD1_k127_6138016_0 protein phosphatase regulator activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 625.0
HFD1_k127_6138016_1 - - - - 0.0002532 48.0
HFD1_k127_6161873_0 nucleosomal DNA binding K11253 GO:0000785,GO:0000786,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0031490,GO:0031491,GO:0031492,GO:0031497,GO:0032991,GO:0032993,GO:0034622,GO:0034728,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0044815,GO:0044877,GO:0051276,GO:0065003,GO:0065004,GO:0071103,GO:0071824,GO:0071840,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008686 265.0
HFD1_k127_6161873_1 chromatin silencing K11251 GO:0000228,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006325,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0031974,GO:0031981,GO:0032991,GO:0032993,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0051276,GO:0070013,GO:0071840,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000001176 240.0
HFD1_k127_6161873_2 protein heterodimerization activity K11252,K11275 - - 0.0000000000000000000000000000000000000000000000000000000000000009503 222.0
HFD1_k127_6161873_3 Histone H2A K11251 GO:0000228,GO:0000785,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006325,GO:0006342,GO:0006355,GO:0006996,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0040029,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051276,GO:0060255,GO:0065007,GO:0070013,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000003883 209.0
HFD1_k127_6177890_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 416.0
HFD1_k127_6177890_1 Zinc metalloprotease (Elastase) K01186,K05994,K21449 - 3.2.1.18,3.4.11.10 0.0000000000000000000000000000000000000000000000000000000000000002473 240.0
HFD1_k127_6177890_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000001318 163.0
HFD1_k127_6177890_3 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.0000000000000000000000002077 111.0
HFD1_k127_617850_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 333.0
HFD1_k127_619681_0 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 529.0
HFD1_k127_6214753_0 Carboxypeptidase regulatory-like domain - - - 0.0 1264.0
HFD1_k127_6214753_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1052.0
HFD1_k127_6214753_10 Prolyl oligopeptidase family - - - 1.868e-241 767.0
HFD1_k127_6214753_100 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000216 166.0
HFD1_k127_6214753_101 Type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000232 186.0
HFD1_k127_6214753_102 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.00000000000000000000000000000000000000009551 154.0
HFD1_k127_6214753_103 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000002546 149.0
HFD1_k127_6214753_104 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000006379 139.0
HFD1_k127_6214753_105 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000006518 139.0
HFD1_k127_6214753_106 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000006576 141.0
HFD1_k127_6214753_107 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000001313 136.0
HFD1_k127_6214753_108 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000006199 135.0
HFD1_k127_6214753_109 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000001015 131.0
HFD1_k127_6214753_11 heat shock protein 70 K04043,K04044 - - 3.821e-218 693.0
HFD1_k127_6214753_110 nucleotidyltransferase activity - - - 0.0000000000000000000000000000003885 131.0
HFD1_k127_6214753_111 - - - - 0.000000000000000000000000000006987 133.0
HFD1_k127_6214753_112 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.00000000000000000000000000001092 121.0
HFD1_k127_6214753_113 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000002931 117.0
HFD1_k127_6214753_114 Methanol dehydrogenase K06872 - - 0.0000000000000000000000000003094 125.0
HFD1_k127_6214753_115 Protein of unknown function (DUF3307) - - - 0.0000000000000000000000000006977 122.0
HFD1_k127_6214753_116 - - - - 0.000000000000000000000001085 113.0
HFD1_k127_6214753_117 Thioredoxin-like - - - 0.00000000000000000000001654 109.0
HFD1_k127_6214753_118 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0000000000000000000003519 97.0
HFD1_k127_6214753_119 C4-type zinc ribbon domain K07164 - - 0.000000000000000000001404 104.0
HFD1_k127_6214753_12 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 4.118e-214 674.0
HFD1_k127_6214753_120 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000002862 97.0
HFD1_k127_6214753_121 - - - - 0.00000000000000000004362 93.0
HFD1_k127_6214753_122 - - - - 0.000000000000005662 77.0
HFD1_k127_6214753_123 - - - - 0.000000000000009873 80.0
HFD1_k127_6214753_124 - - - - 0.00000000000005884 83.0
HFD1_k127_6214753_125 AraC-like ligand binding domain - - - 0.0000000000001341 75.0
HFD1_k127_6214753_126 Roadblock/LC7 domain - - - 0.000000000000162 75.0
HFD1_k127_6214753_127 SatD family (SatD) - - - 0.000000000001162 76.0
HFD1_k127_6214753_128 Bacterial regulatory protein, Fis family - - - 0.0000000004722 64.0
HFD1_k127_6214753_129 - - - - 0.0000000145 61.0
HFD1_k127_6214753_13 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 1.382e-200 630.0
HFD1_k127_6214753_130 Pilus assembly protein, PilO K02664 - - 0.00000001942 64.0
HFD1_k127_6214753_131 PFAM TonB-dependent Receptor Plug - - - 0.0000001254 63.0
HFD1_k127_6214753_132 PFAM Tetratricopeptide - - - 0.0000001774 62.0
HFD1_k127_6214753_133 - - - - 0.0000008233 60.0
HFD1_k127_6214753_135 colicin V production K03558 - - 0.000004765 56.0
HFD1_k127_6214753_136 repeat-containing protein - - - 0.000008738 57.0
HFD1_k127_6214753_137 - K06950 - - 0.0000478 49.0
HFD1_k127_6214753_138 PFAM sigma-70 region 2 domain protein K03088 - - 0.00007794 54.0
HFD1_k127_6214753_139 helicase activity - - - 0.00009115 53.0
HFD1_k127_6214753_14 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 611.0
HFD1_k127_6214753_140 hyperosmotic response - - - 0.00009892 51.0
HFD1_k127_6214753_141 AMIN domain K01448 - 3.5.1.28 0.0001244 56.0
HFD1_k127_6214753_142 PFAM ThiJ PfpI - - - 0.0002033 46.0
HFD1_k127_6214753_143 PFAM Fimbrial assembly family protein K02663 - - 0.0002819 51.0
HFD1_k127_6214753_144 Cell division protein FtsQ K03589 - - 0.0005669 51.0
HFD1_k127_6214753_145 - - - - 0.0007529 49.0
HFD1_k127_6214753_146 alpha-galactosidase K01179,K01183 - 3.2.1.14,3.2.1.4 0.0009088 51.0
HFD1_k127_6214753_15 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 593.0
HFD1_k127_6214753_16 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 591.0
HFD1_k127_6214753_17 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 569.0
HFD1_k127_6214753_18 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 579.0
HFD1_k127_6214753_19 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 565.0
HFD1_k127_6214753_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.464e-305 947.0
HFD1_k127_6214753_20 Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 548.0
HFD1_k127_6214753_21 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 545.0
HFD1_k127_6214753_22 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 518.0
HFD1_k127_6214753_23 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 518.0
HFD1_k127_6214753_24 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 505.0
HFD1_k127_6214753_25 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 461.0
HFD1_k127_6214753_26 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 467.0
HFD1_k127_6214753_27 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 448.0
HFD1_k127_6214753_28 DNA polymerase K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 457.0
HFD1_k127_6214753_29 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 448.0
HFD1_k127_6214753_3 PFAM Prolyl oligopeptidase family - - - 2.975e-291 906.0
HFD1_k127_6214753_30 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 455.0
HFD1_k127_6214753_31 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 440.0
HFD1_k127_6214753_32 proteins of the AP superfamily K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 441.0
HFD1_k127_6214753_33 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 457.0
HFD1_k127_6214753_34 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 436.0
HFD1_k127_6214753_35 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 429.0
HFD1_k127_6214753_36 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 430.0
HFD1_k127_6214753_37 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 428.0
HFD1_k127_6214753_38 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 424.0
HFD1_k127_6214753_39 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 442.0
HFD1_k127_6214753_4 hydrolase, family 3 K05349 - 3.2.1.21 5.275e-281 883.0
HFD1_k127_6214753_40 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 416.0
HFD1_k127_6214753_41 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 415.0
HFD1_k127_6214753_42 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 409.0
HFD1_k127_6214753_43 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 411.0
HFD1_k127_6214753_44 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 393.0
HFD1_k127_6214753_45 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 400.0
HFD1_k127_6214753_46 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 395.0
HFD1_k127_6214753_47 Domain of unknown function (DUF3471) K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 400.0
HFD1_k127_6214753_48 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 401.0
HFD1_k127_6214753_49 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 379.0
HFD1_k127_6214753_5 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 5.284e-276 854.0
HFD1_k127_6214753_50 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 375.0
HFD1_k127_6214753_51 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 363.0
HFD1_k127_6214753_52 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 361.0
HFD1_k127_6214753_53 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 350.0
HFD1_k127_6214753_54 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 353.0
HFD1_k127_6214753_55 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 344.0
HFD1_k127_6214753_56 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 332.0
HFD1_k127_6214753_57 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 325.0
HFD1_k127_6214753_58 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 329.0
HFD1_k127_6214753_59 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 314.0
HFD1_k127_6214753_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.252e-273 854.0
HFD1_k127_6214753_60 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 303.0
HFD1_k127_6214753_61 PFAM YdjC family protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 302.0
HFD1_k127_6214753_62 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 288.0
HFD1_k127_6214753_63 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 287.0
HFD1_k127_6214753_64 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001464 284.0
HFD1_k127_6214753_65 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002196 286.0
HFD1_k127_6214753_66 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007108 286.0
HFD1_k127_6214753_67 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001349 292.0
HFD1_k127_6214753_68 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
HFD1_k127_6214753_69 TIGRFAM sulfate ABC transporter K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004043 279.0
HFD1_k127_6214753_7 Sodium:solute symporter family K03307 - - 2.787e-259 809.0
HFD1_k127_6214753_70 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001642 271.0
HFD1_k127_6214753_71 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005325 273.0
HFD1_k127_6214753_72 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006033 274.0
HFD1_k127_6214753_73 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001587 290.0
HFD1_k127_6214753_74 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005293 268.0
HFD1_k127_6214753_75 sulfate ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003156 269.0
HFD1_k127_6214753_76 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000893 250.0
HFD1_k127_6214753_77 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000003168 239.0
HFD1_k127_6214753_78 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000345 243.0
HFD1_k127_6214753_79 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000105 232.0
HFD1_k127_6214753_8 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 6.481e-247 771.0
HFD1_k127_6214753_80 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005436 241.0
HFD1_k127_6214753_81 ZIP Zinc transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000005216 231.0
HFD1_k127_6214753_82 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000008366 234.0
HFD1_k127_6214753_83 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000009381 224.0
HFD1_k127_6214753_84 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000001997 224.0
HFD1_k127_6214753_85 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000004936 224.0
HFD1_k127_6214753_86 PFAM YdjC family protein - - - 0.0000000000000000000000000000000000000000000000000000000007437 211.0
HFD1_k127_6214753_87 TIGRFAM SUF system FeS K04488 - - 0.00000000000000000000000000000000000000000000000000000003926 201.0
HFD1_k127_6214753_88 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000004144 209.0
HFD1_k127_6214753_89 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000004608 196.0
HFD1_k127_6214753_9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.678e-246 770.0
HFD1_k127_6214753_90 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000003438 193.0
HFD1_k127_6214753_91 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000008712 188.0
HFD1_k127_6214753_92 phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000001413 202.0
HFD1_k127_6214753_93 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001913 187.0
HFD1_k127_6214753_94 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000005094 192.0
HFD1_k127_6214753_95 - - - - 0.000000000000000000000000000000000000000000000000008477 187.0
HFD1_k127_6214753_96 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000009731 187.0
HFD1_k127_6214753_97 PFAM Nickel cobalt transporter, high-affinity - - - 0.0000000000000000000000000000000000000000000000116 179.0
HFD1_k127_6214753_98 PFAM heat shock protein DnaJ K04082 - - 0.00000000000000000000000000000000000000000000003412 179.0
HFD1_k127_6214753_99 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000007435 173.0
HFD1_k127_6247840_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003671 281.0
HFD1_k127_6247840_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000005348 205.0
HFD1_k127_6261164_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000003848 204.0
HFD1_k127_6261164_1 Transposase - - - 0.00000000000000000000000000003148 132.0
HFD1_k127_6261164_2 transposase activity - - - 0.000000000000000000004757 95.0
HFD1_k127_6263024_0 PFAM Na-Ca exchanger integrin-beta4 - - - 0.000000000000000000000000000000000000000000000000000005853 207.0
HFD1_k127_6288390_0 - - - - 0.0000000000000000000000006141 117.0
HFD1_k127_6289327_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 349.0
HFD1_k127_6289327_1 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002001 271.0
HFD1_k127_6289327_2 - - - - 0.000000000000000000000000000000003347 141.0
HFD1_k127_6289327_3 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000001356 113.0
HFD1_k127_6289327_4 SNARE associated Golgi protein - - - 0.00000000000004554 78.0
HFD1_k127_6289703_0 Domain of unknown function (DUF3390) K18929 - - 0.000000000000000000000000000000000000000000000001204 179.0
HFD1_k127_6289703_1 LUD domain K00782 - - 0.00000000000000000000000000008195 124.0
HFD1_k127_6289703_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000003399 97.0
HFD1_k127_6289703_4 bacterial OsmY and nodulation domain - - - 0.0000000000000005664 85.0
HFD1_k127_6289703_5 PhoQ Sensor - - - 0.00008191 48.0
HFD1_k127_631680_0 Integrase, catalytic region - - - 2.158e-205 643.0
HFD1_k127_631680_1 - - - - 0.000000000000000000000000000000000000009824 152.0
HFD1_k127_631680_2 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000351 114.0
HFD1_k127_6365643_0 transposition K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008276 270.0
HFD1_k127_6365643_1 Evidence 2b Function of strongly homologous gene - - - 0.000005136 53.0
HFD1_k127_6441431_0 UvrD/REP helicase N-terminal domain - - - 0.0 1094.0
HFD1_k127_6441431_1 DNA polymerase Ligase (LigD) - - - 1.046e-296 929.0
HFD1_k127_6441431_10 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001954 274.0
HFD1_k127_6441431_11 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005812 257.0
HFD1_k127_6441431_12 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 255.0
HFD1_k127_6441431_13 deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002922 249.0
HFD1_k127_6441431_14 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000001179 231.0
HFD1_k127_6441431_15 - - - - 0.0000000000000000000000000003037 119.0
HFD1_k127_6441431_16 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000241 96.0
HFD1_k127_6441431_17 WD40-like Beta Propeller Repeat - - - 0.0002909 51.0
HFD1_k127_6441431_2 PD-(D/E)XK nuclease superfamily - - - 1.222e-290 927.0
HFD1_k127_6441431_3 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 7.202e-200 635.0
HFD1_k127_6441431_4 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 606.0
HFD1_k127_6441431_5 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 526.0
HFD1_k127_6441431_6 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 404.0
HFD1_k127_6441431_7 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 365.0
HFD1_k127_6441431_8 Transcriptional regulator K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 334.0
HFD1_k127_6441431_9 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000743 279.0
HFD1_k127_6442118_0 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 3.206e-212 672.0
HFD1_k127_6442118_1 - - - - 0.000000000000000000000000004718 115.0
HFD1_k127_6442118_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000005092 111.0
HFD1_k127_6442118_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000005077 73.0
HFD1_k127_6442118_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000006365 74.0
HFD1_k127_6442118_5 alcohol dehydrogenase K17760 - 1.1.9.1 0.000001078 52.0
HFD1_k127_6442118_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000537 52.0
HFD1_k127_6442118_7 Glycosyl transferase family 41 - - - 0.000356 53.0
HFD1_k127_6444281_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 338.0
HFD1_k127_6446027_0 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 349.0
HFD1_k127_6449383_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 536.0
HFD1_k127_6449383_1 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 494.0
HFD1_k127_6449383_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 365.0
HFD1_k127_6449383_3 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006312 286.0
HFD1_k127_6449383_4 Peptidase, S9A B C family, catalytic domain protein - - - 0.0000000000000000000000000000000000000000000001408 177.0
HFD1_k127_6449383_5 Belongs to the ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000002029 149.0
HFD1_k127_6449383_6 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.000000000000000000000000000000004202 142.0
HFD1_k127_6449383_7 von Willebrand factor, type A K07114 - - 0.000000151 63.0
HFD1_k127_6449383_8 Beta-lactamase - - - 0.0000002369 57.0
HFD1_k127_6450780_0 Carboxypeptidase regulatory-like domain - - - 8.907e-218 715.0
HFD1_k127_6450780_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 523.0
HFD1_k127_6450780_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 437.0
HFD1_k127_6450780_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000008682 98.0
HFD1_k127_6450780_4 cAMP biosynthetic process - - - 0.0005693 43.0
HFD1_k127_6460430_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 375.0
HFD1_k127_6471324_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 351.0
HFD1_k127_6471324_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 331.0
HFD1_k127_6471324_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000645 240.0
HFD1_k127_6471324_3 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000000547 114.0
HFD1_k127_6471324_4 - - - - 0.00000000003602 75.0
HFD1_k127_6471851_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000248 234.0
HFD1_k127_6471851_1 DDE superfamily endonuclease - - - 0.0000000000000000000000000000008862 123.0
HFD1_k127_6471851_2 DDE superfamily endonuclease - - - 0.00000000000000002677 92.0
HFD1_k127_6472534_0 protein heterodimerization activity K11252,K11275 - - 0.00000000000000000000000000000000000000000000000000000000000001648 216.0
HFD1_k127_647522_0 - - - - 0.0000000000000000000000000000000000003235 143.0
HFD1_k127_647522_1 DNA methylase K07316 - 2.1.1.72 0.0000001163 55.0
HFD1_k127_647522_2 Amidohydrolase family - - - 0.000000566 54.0
HFD1_k127_6482837_0 Galactose oxidase, central domain - - - 0.0000000000000003163 84.0
HFD1_k127_6482837_1 RNA-directed DNA polymerase from mobile element jockey-like - - - 0.000001954 56.0
HFD1_k127_6485089_0 RNA-directed DNA polymerase from mobile element jockey-like - - - 0.000004603 53.0
HFD1_k127_6498723_0 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000000000000000000000000000000000000002707 238.0
HFD1_k127_6498723_1 - - - - 0.000000000000000000000000001963 120.0
HFD1_k127_6498723_2 Cadherin repeats. - - - 0.0000000000000005771 93.0
HFD1_k127_6498723_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000004701 70.0
HFD1_k127_6498723_4 - - - - 0.00001459 53.0
HFD1_k127_6498724_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 490.0
HFD1_k127_6498724_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000342 71.0
HFD1_k127_6510310_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 503.0
HFD1_k127_6510310_1 RmlD substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 409.0
HFD1_k127_6510310_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 310.0
HFD1_k127_6510310_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000004455 225.0
HFD1_k127_6510310_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000111 182.0
HFD1_k127_6510310_5 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000003176 103.0
HFD1_k127_6510310_6 PD-(D/E)XK nuclease superfamily - - - 0.000003318 52.0
HFD1_k127_6511057_0 hydrolase, family 3 K05349 - 3.2.1.21 3.345e-266 845.0
HFD1_k127_6511057_1 Belongs to the glycosyl hydrolase 3 family K05349 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.21 6.246e-256 811.0
HFD1_k127_6511057_10 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 387.0
HFD1_k127_6511057_11 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 360.0
HFD1_k127_6511057_12 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 327.0
HFD1_k127_6511057_13 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 312.0
HFD1_k127_6511057_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 308.0
HFD1_k127_6511057_15 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 291.0
HFD1_k127_6511057_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004021 261.0
HFD1_k127_6511057_17 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004267 249.0
HFD1_k127_6511057_18 - - - - 0.0000000000000000000000000000000000000000000000000001881 211.0
HFD1_k127_6511057_19 DinB family - - - 0.0000000000000000000000000000000000000000004069 163.0
HFD1_k127_6511057_2 ASPIC and UnbV - - - 2.261e-227 717.0
HFD1_k127_6511057_20 Xylose isomerase - - - 0.0000000000000000000000000000000000001737 147.0
HFD1_k127_6511057_21 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000003681 105.0
HFD1_k127_6511057_22 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000297 113.0
HFD1_k127_6511057_23 Tetratricopeptide repeat - - - 0.0001025 54.0
HFD1_k127_6511057_3 Beta-lactamase - - - 1.593e-198 627.0
HFD1_k127_6511057_4 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 632.0
HFD1_k127_6511057_5 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 603.0
HFD1_k127_6511057_6 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 532.0
HFD1_k127_6511057_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 515.0
HFD1_k127_6511057_8 gluconolactonase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 472.0
HFD1_k127_6511057_9 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 459.0
HFD1_k127_6516378_0 Chaperone of endosialidase - - - 0.0000004679 61.0
HFD1_k127_6517615_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 499.0
HFD1_k127_6517615_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000005562 72.0
HFD1_k127_6524142_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 3.53e-321 1005.0
HFD1_k127_6524142_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 319.0
HFD1_k127_6524142_2 Domain of unknown function (DUF2383) - - - 0.0000000000000000000000000000000000000000005139 166.0
HFD1_k127_6524142_3 Transcriptional regulator - - - 0.00000000000000000000000000000000002344 143.0
HFD1_k127_6524142_4 DinB family - - - 0.000000000000000000000002045 110.0
HFD1_k127_6530827_0 - - - - 0.00000000000000000000000000001033 123.0
HFD1_k127_6530827_1 Tetratricopeptide repeat - - - 0.000001355 54.0
HFD1_k127_6541862_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 434.0
HFD1_k127_6547776_0 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 520.0
HFD1_k127_6564310_0 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000871 75.0
HFD1_k127_6564310_1 PQQ-like domain K00114 - 1.1.2.8 0.000000005973 57.0
HFD1_k127_6564310_2 Helix-turn-helix domain - - - 0.00007283 48.0
HFD1_k127_6606529_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 467.0
HFD1_k127_6616642_0 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 328.0
HFD1_k127_6616642_1 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002507 261.0
HFD1_k127_6616642_2 - - - - 0.00000000000000000000007712 106.0
HFD1_k127_6616642_3 S-layer homology domain - - - 0.000000000000002913 91.0
HFD1_k127_6616642_4 - - - - 0.0000000006316 66.0
HFD1_k127_6616642_5 Chaperone of endosialidase K21449 - - 0.000404 47.0
HFD1_k127_6621387_0 Hep Hag repeat protein K11904,K21449 - - 0.0003277 52.0
HFD1_k127_6622929_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 6.906e-312 973.0
HFD1_k127_6622929_1 cellulose binding - - - 1.172e-223 696.0
HFD1_k127_6622929_10 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 366.0
HFD1_k127_6622929_11 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 341.0
HFD1_k127_6622929_12 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 297.0
HFD1_k127_6622929_13 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009006 276.0
HFD1_k127_6622929_14 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 252.0
HFD1_k127_6622929_15 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003964 243.0
HFD1_k127_6622929_16 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
HFD1_k127_6622929_17 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000000000008714 206.0
HFD1_k127_6622929_18 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
HFD1_k127_6622929_19 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000000000003993 204.0
HFD1_k127_6622929_2 Erythromycin esterase - - - 7.67e-199 628.0
HFD1_k127_6622929_20 - - - - 0.0000000000000000000000000000000000000000000000000000004919 201.0
HFD1_k127_6622929_21 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000005798 194.0
HFD1_k127_6622929_22 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002428 179.0
HFD1_k127_6622929_23 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000008211 186.0
HFD1_k127_6622929_24 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000001052 169.0
HFD1_k127_6622929_26 - - - - 0.000000000000000000000000000000000000000000005186 176.0
HFD1_k127_6622929_27 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000003847 162.0
HFD1_k127_6622929_28 YCII-related domain - - - 0.0000000000000000000000000000000000000001579 153.0
HFD1_k127_6622929_29 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000001564 152.0
HFD1_k127_6622929_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 1.553e-196 644.0
HFD1_k127_6622929_30 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000002173 141.0
HFD1_k127_6622929_31 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000002963 140.0
HFD1_k127_6622929_33 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000003145 129.0
HFD1_k127_6622929_34 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000001977 128.0
HFD1_k127_6622929_35 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000008086 115.0
HFD1_k127_6622929_36 Tyrosine phosphatase family - - - 0.00000000000000000000001035 109.0
HFD1_k127_6622929_37 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000002293 111.0
HFD1_k127_6622929_38 AMP binding - - - 0.000000000000000000000192 108.0
HFD1_k127_6622929_4 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 589.0
HFD1_k127_6622929_40 Universal stress protein - - - 0.00000000000000000001979 96.0
HFD1_k127_6622929_41 AMP binding - - - 0.0000000000000000009418 97.0
HFD1_k127_6622929_42 Universal stress protein family - - - 0.000000000000000001272 96.0
HFD1_k127_6622929_43 - - - - 0.000000000001138 70.0
HFD1_k127_6622929_44 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.0000000003559 61.0
HFD1_k127_6622929_45 AMP binding - - - 0.0000000004455 70.0
HFD1_k127_6622929_47 Domain of unknown function (DUF4956) - - - 0.000000001877 69.0
HFD1_k127_6622929_48 COG0457 FOG TPR repeat - - - 0.0000002168 62.0
HFD1_k127_6622929_49 von Willebrand factor, type A K07114 - - 0.000004835 58.0
HFD1_k127_6622929_5 RNA polymerase, sigma subunit, ECF family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 572.0
HFD1_k127_6622929_50 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0001144 53.0
HFD1_k127_6622929_6 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 571.0
HFD1_k127_6622929_7 Cellulase (glycosyl hydrolase family 5) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 531.0
HFD1_k127_6622929_8 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 395.0
HFD1_k127_6622929_9 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 377.0
HFD1_k127_6628560_0 TonB dependent receptor - - - 1.03e-242 781.0
HFD1_k127_6628560_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 620.0
HFD1_k127_6628560_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004771 265.0
HFD1_k127_6628560_12 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001214 203.0
HFD1_k127_6628560_13 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000008102 203.0
HFD1_k127_6628560_14 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000000000000000000000000000000000000000000005663 193.0
HFD1_k127_6628560_15 Transcriptional regulator, Crp Fnr family K10914 - - 0.00000000000000000000000000000000000000000000000002113 187.0
HFD1_k127_6628560_16 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000000003658 186.0
HFD1_k127_6628560_17 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000001961 184.0
HFD1_k127_6628560_18 - - - - 0.000000000000000000000000000000000000000000000003608 186.0
HFD1_k127_6628560_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000002562 175.0
HFD1_k127_6628560_2 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 567.0
HFD1_k127_6628560_20 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000243 166.0
HFD1_k127_6628560_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000002352 168.0
HFD1_k127_6628560_22 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000005481 161.0
HFD1_k127_6628560_23 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000002081 152.0
HFD1_k127_6628560_24 TonB dependent receptor K02014,K16087 - - 0.0000000000000000000000000000000002807 153.0
HFD1_k127_6628560_25 guanyl-nucleotide exchange factor activity K06978,K12287,K21105 - 3.1.1.102 0.00000000000000000000000000000000052 152.0
HFD1_k127_6628560_26 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000006061 138.0
HFD1_k127_6628560_27 ABC-2 family transporter protein - - - 0.00000000000000000000000000000001177 132.0
HFD1_k127_6628560_28 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.00000000000000000000000002016 113.0
HFD1_k127_6628560_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 542.0
HFD1_k127_6628560_30 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000001772 111.0
HFD1_k127_6628560_31 amine dehydrogenase activity - - - 0.0000000000000000000000004282 123.0
HFD1_k127_6628560_32 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000197 106.0
HFD1_k127_6628560_33 Transglycosylase associated protein - - - 0.000000000000000000000002466 104.0
HFD1_k127_6628560_34 SnoaL-like polyketide cyclase - - - 0.00000000000000000000005866 102.0
HFD1_k127_6628560_35 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000003579 96.0
HFD1_k127_6628560_36 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000005451 100.0
HFD1_k127_6628560_37 Response regulator, receiver K06147 - - 0.0000000000000000123 87.0
HFD1_k127_6628560_38 Response regulator, receiver - - - 0.00000000000000002006 87.0
HFD1_k127_6628560_39 - - - - 0.0000000000005159 70.0
HFD1_k127_6628560_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 519.0
HFD1_k127_6628560_40 Pyruvate phosphate dikinase - - - 0.000000000006925 66.0
HFD1_k127_6628560_41 Osmotically inducible protein Y K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.00000000002496 74.0
HFD1_k127_6628560_42 ErfK ybiS ycfS ynhG family protein K16291 - - 0.00000000008438 74.0
HFD1_k127_6628560_44 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0002277 51.0
HFD1_k127_6628560_45 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0004488 47.0
HFD1_k127_6628560_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 512.0
HFD1_k127_6628560_6 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 477.0
HFD1_k127_6628560_7 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 458.0
HFD1_k127_6628560_8 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 426.0
HFD1_k127_6628560_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 336.0
HFD1_k127_6629333_0 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 413.0
HFD1_k127_6629333_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 359.0
HFD1_k127_6629333_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 338.0
HFD1_k127_6629333_3 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002439 280.0
HFD1_k127_6629333_4 Response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000001402 240.0
HFD1_k127_6629333_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000001994 173.0
HFD1_k127_6629333_6 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000003256 113.0
HFD1_k127_6629333_7 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.0000000003041 67.0
HFD1_k127_6635096_0 R3H domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 612.0
HFD1_k127_6635096_1 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 584.0
HFD1_k127_6635096_10 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 312.0
HFD1_k127_6635096_11 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 297.0
HFD1_k127_6635096_12 PFAM type I phosphodiesterase nucleotide pyrophosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001092 293.0
HFD1_k127_6635096_13 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000009406 220.0
HFD1_k127_6635096_14 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000186 218.0
HFD1_k127_6635096_15 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000009401 195.0
HFD1_k127_6635096_16 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000227 154.0
HFD1_k127_6635096_17 ABC-2 family transporter protein - - - 0.00000000000000000000000003108 118.0
HFD1_k127_6635096_18 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000508 125.0
HFD1_k127_6635096_2 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 522.0
HFD1_k127_6635096_20 DinB superfamily - - - 0.0000000000000001144 86.0
HFD1_k127_6635096_21 hydrolase family 81 - - - 0.0000000000001614 83.0
HFD1_k127_6635096_22 Tetratricopeptide repeat - - - 0.00000000003636 76.0
HFD1_k127_6635096_23 - - - - 0.000000001498 68.0
HFD1_k127_6635096_24 type II secretion system protein K - - - 0.00002487 57.0
HFD1_k127_6635096_25 Type IV Pilus-assembly protein W K02672 - - 0.00003681 56.0
HFD1_k127_6635096_26 type IV pilus modification protein PilV K02458,K02671 - - 0.0001528 51.0
HFD1_k127_6635096_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 426.0
HFD1_k127_6635096_4 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 395.0
HFD1_k127_6635096_5 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 397.0
HFD1_k127_6635096_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 353.0
HFD1_k127_6635096_7 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 342.0
HFD1_k127_6635096_8 Predicted membrane protein (DUF2238) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 329.0
HFD1_k127_6635096_9 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 328.0
HFD1_k127_6638354_0 Transposase K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 301.0
HFD1_k127_6658202_0 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 348.0
HFD1_k127_6658202_1 Transposase K07483 - - 0.0000000000000000000000001378 109.0
HFD1_k127_6663271_0 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001793 243.0
HFD1_k127_6663271_1 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000001339 220.0
HFD1_k127_6663271_2 Transposase - - - 0.000006003 57.0
HFD1_k127_6663271_3 Phage integrase, N-terminal SAM-like domain - - - 0.0001648 50.0
HFD1_k127_6664411_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 509.0
HFD1_k127_6664411_1 DDE_Tnp_1-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009452 271.0
HFD1_k127_6664411_2 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003976 227.0
HFD1_k127_6667687_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 492.0
HFD1_k127_6667687_1 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000002237 65.0
HFD1_k127_6667687_2 - - - - 0.000255 47.0
HFD1_k127_6705614_0 One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation K02704 - - 0.00003002 48.0
HFD1_k127_6719500_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006848 271.0
HFD1_k127_6719500_1 transposase activity - - - 0.00002116 50.0
HFD1_k127_67241_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 555.0
HFD1_k127_67241_1 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 511.0
HFD1_k127_67241_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 361.0
HFD1_k127_67241_3 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 332.0
HFD1_k127_67241_4 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 312.0
HFD1_k127_67241_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004625 281.0
HFD1_k127_67241_6 Prolyl oligopeptidase family - - - 0.0000000000000000000000000008949 124.0
HFD1_k127_67241_7 - - - - 0.0000000000001473 78.0
HFD1_k127_6724936_0 Transposase IS116/IS110/IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 471.0
HFD1_k127_6724936_1 Transposase - - - 0.000000000000000000000000000000000000000000000005913 181.0
HFD1_k127_6724936_2 transposase activity - - - 0.0000000000009899 68.0
HFD1_k127_6729688_0 Carboxypeptidase regulatory-like domain - - - 0.0 1236.0
HFD1_k127_6729688_10 - - - - 0.0000000000000000000000000000000002954 134.0
HFD1_k127_6729688_11 lactoylglutathione lyase activity - - - 0.0000000000000000000000000001274 119.0
HFD1_k127_6729688_12 Glyoxalase-like domain - - - 0.0000000000000001657 84.0
HFD1_k127_6729688_13 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000003926 77.0
HFD1_k127_6729688_14 - - - - 0.000000000000004141 81.0
HFD1_k127_6729688_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000001473 77.0
HFD1_k127_6729688_16 - K07039 - - 0.00000001257 60.0
HFD1_k127_6729688_17 PFAM amidohydrolase - - - 0.0000005461 53.0
HFD1_k127_6729688_18 Bacterial protein of unknown function (DUF899) - - - 0.0000144 53.0
HFD1_k127_6729688_19 PFAM amidohydrolase - - - 0.0001025 46.0
HFD1_k127_6729688_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 593.0
HFD1_k127_6729688_3 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 485.0
HFD1_k127_6729688_4 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 462.0
HFD1_k127_6729688_5 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 354.0
HFD1_k127_6729688_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005593 246.0
HFD1_k127_6729688_7 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000000006165 221.0
HFD1_k127_6729688_8 - - - - 0.0000000000000000000000000000000000000000000000000000002669 207.0
HFD1_k127_6729688_9 - - - - 0.0000000000000000000000000000000000000004382 149.0
HFD1_k127_6733611_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.423e-276 862.0
HFD1_k127_6733611_1 PFAM TonB-dependent Receptor K16090 - - 1.108e-222 715.0
HFD1_k127_6733611_10 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 329.0
HFD1_k127_6733611_11 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 325.0
HFD1_k127_6733611_12 Acts as a magnesium transporter K03281,K04767,K06213,K15986 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 325.0
HFD1_k127_6733611_13 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 312.0
HFD1_k127_6733611_14 Belongs to the GPAT DAPAT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005573 287.0
HFD1_k127_6733611_15 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000009791 241.0
HFD1_k127_6733611_16 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000002402 233.0
HFD1_k127_6733611_17 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000008969 199.0
HFD1_k127_6733611_18 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000002535 200.0
HFD1_k127_6733611_19 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.000000000000000000000000000000000001052 146.0
HFD1_k127_6733611_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 612.0
HFD1_k127_6733611_20 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000002038 136.0
HFD1_k127_6733611_21 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000006774 112.0
HFD1_k127_6733611_22 PFAM von Willebrand factor type A - - - 0.0000000000000000000000135 115.0
HFD1_k127_6733611_23 Domain of unknown function (DUF4870) - - - 0.00000000000005207 78.0
HFD1_k127_6733611_24 peptidyl-tyrosine sulfation - - - 0.000000000002739 78.0
HFD1_k127_6733611_25 Tetratricopeptide repeats - - - 0.00000003939 65.0
HFD1_k127_6733611_26 SnoaL-like polyketide cyclase - - - 0.0000004295 61.0
HFD1_k127_6733611_27 SnoaL-like domain - - - 0.0009063 51.0
HFD1_k127_6733611_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 485.0
HFD1_k127_6733611_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 408.0
HFD1_k127_6733611_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 383.0
HFD1_k127_6733611_6 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 383.0
HFD1_k127_6733611_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 371.0
HFD1_k127_6733611_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 360.0
HFD1_k127_6733611_9 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 355.0
HFD1_k127_6737298_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 612.0
HFD1_k127_6737298_1 ECF sigma factor - - - 0.0000000000000000000000000000000001281 137.0
HFD1_k127_6783356_0 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000009398 193.0
HFD1_k127_6791098_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 586.0
HFD1_k127_6793821_0 FtsX-like permease family - - - 9.146e-218 718.0
HFD1_k127_6793821_1 COG1012 NAD-dependent aldehyde - - - 4.054e-209 659.0
HFD1_k127_6793821_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 577.0
HFD1_k127_6793821_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 480.0
HFD1_k127_6793821_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 353.0
HFD1_k127_6793821_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004935 279.0
HFD1_k127_6793821_6 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000000000000000000000002008 141.0
HFD1_k127_6793821_7 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000000000000000000000002814 137.0
HFD1_k127_6793821_8 PQQ-like domain - - - 0.00000000000000000000004493 102.0
HFD1_k127_6793821_9 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000005904 68.0
HFD1_k127_6794463_0 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 606.0
HFD1_k127_6794463_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 401.0
HFD1_k127_6794463_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 370.0
HFD1_k127_6794463_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003245 227.0
HFD1_k127_6794463_4 - - - - 0.000000000000000000000000000000000000000000000000000000001496 206.0
HFD1_k127_6794463_5 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000022 190.0
HFD1_k127_6794463_6 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.0000000000000000000003731 103.0
HFD1_k127_6794463_8 Belongs to the UPF0337 (CsbD) family - - - 0.0001373 48.0
HFD1_k127_6795134_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
HFD1_k127_6795134_1 Transposase - - - 0.00000000000000000000000000000000000000003949 157.0
HFD1_k127_6795134_2 PFAM transposase, IS4 family protein - - - 0.000002909 51.0
HFD1_k127_6802236_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 380.0
HFD1_k127_6802236_1 Cation efflux family K16264 - - 0.000000000000000000000000000000001881 132.0
HFD1_k127_6802236_2 TIGRFAM iron-sulfur cluster assembly accessory protein - - - 0.0000000000000000000006318 100.0
HFD1_k127_6803217_0 Heparinase II/III N-terminus - - - 0.000004152 58.0
HFD1_k127_6811585_0 Belongs to the TPP enzyme family K03336 GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 1.567e-255 801.0
HFD1_k127_6811585_1 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 462.0
HFD1_k127_6811585_2 helix_turn _helix lactose operon repressor K05499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 436.0
HFD1_k127_6811585_3 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 427.0
HFD1_k127_6811585_4 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 412.0
HFD1_k127_6811585_5 TonB-dependent Receptor Plug Domain - - - 0.0000000000001128 73.0
HFD1_k127_6820450_0 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000004028 211.0
HFD1_k127_6835456_0 repeat protein - - - 3.177e-288 898.0
HFD1_k127_6835456_1 Protein kinase domain K12132 - 2.7.11.1 5.058e-198 648.0
HFD1_k127_6835456_2 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000878 253.0
HFD1_k127_6835456_3 methylisocitrate lyase activity K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000738 194.0
HFD1_k127_6835456_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000001371 51.0
HFD1_k127_6851107_0 PrkA AAA domain protein K07180 - - 9.426e-300 932.0
HFD1_k127_6851107_1 Elongation factor G, domain IV K02355 - - 2.232e-244 773.0
HFD1_k127_6851107_10 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 405.0
HFD1_k127_6851107_11 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 383.0
HFD1_k127_6851107_12 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 327.0
HFD1_k127_6851107_13 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 291.0
HFD1_k127_6851107_14 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001741 286.0
HFD1_k127_6851107_15 enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000003221 236.0
HFD1_k127_6851107_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000008324 226.0
HFD1_k127_6851107_17 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001233 226.0
HFD1_k127_6851107_18 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000001819 217.0
HFD1_k127_6851107_19 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000004224 190.0
HFD1_k127_6851107_2 SMART Elongator protein 3 MiaB NifB - - - 1.37e-233 733.0
HFD1_k127_6851107_20 Soluble NSF attachment protein, SNAP - - - 0.0000000000000000000000000000000000000000000000007113 201.0
HFD1_k127_6851107_21 CHAT domain - - - 0.0000000000000000000000000000000000000000000854 185.0
HFD1_k127_6851107_22 Putative glycolipid-binding K09957 - - 0.0000000000000000000000000000000000000000004642 164.0
HFD1_k127_6851107_23 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000005684 151.0
HFD1_k127_6851107_24 - - - - 0.0000000000000000000000000000000000011 145.0
HFD1_k127_6851107_25 response to abiotic stimulus - - - 0.000000000000000000000000004707 117.0
HFD1_k127_6851107_26 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000000001396 91.0
HFD1_k127_6851107_27 Protein of unknown function (DUF3108) - - - 0.000000000000000004089 96.0
HFD1_k127_6851107_29 Domain of unknown function (DUF4129) - - - 0.000000000004469 78.0
HFD1_k127_6851107_3 radical SAM domain protein - - - 2.309e-221 698.0
HFD1_k127_6851107_30 CAAX protease self-immunity - - - 0.00000000001909 74.0
HFD1_k127_6851107_31 pathogenesis K02417,K02519 - - 0.00000000003538 75.0
HFD1_k127_6851107_32 Glycosyltransferase like family - - - 0.000000042 66.0
HFD1_k127_6851107_33 BON domain - - - 0.0001482 51.0
HFD1_k127_6851107_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 552.0
HFD1_k127_6851107_5 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 550.0
HFD1_k127_6851107_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 478.0
HFD1_k127_6851107_7 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 464.0
HFD1_k127_6851107_8 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 409.0
HFD1_k127_6851107_9 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 397.0
HFD1_k127_6858654_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 307.0
HFD1_k127_6858654_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000004045 183.0
HFD1_k127_6878186_0 lipopolysaccharide transport K22110 - - 0.0 1442.0
HFD1_k127_6878186_1 Large extracellular alpha-helical protein K06894 - - 0.0 1441.0
HFD1_k127_6878186_10 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 349.0
HFD1_k127_6878186_11 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 311.0
HFD1_k127_6878186_12 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 298.0
HFD1_k127_6878186_13 Glycogen debranching enzyme K18206 - 3.2.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000002334 268.0
HFD1_k127_6878186_14 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000007719 224.0
HFD1_k127_6878186_15 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000005946 218.0
HFD1_k127_6878186_16 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.0000000000000000000000000000000000000000000000000000215 191.0
HFD1_k127_6878186_17 Yhs domain-containing protein - - - 0.00000000000000000000000000000000000000000000000001592 184.0
HFD1_k127_6878186_18 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000004064 190.0
HFD1_k127_6878186_19 Peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000315 190.0
HFD1_k127_6878186_2 Sortilin, neurotensin receptor 3, - - - 0.0 1134.0
HFD1_k127_6878186_20 SMART Mov34 MPN PAD-1 family protein - - - 0.0000000000000000000000003607 112.0
HFD1_k127_6878186_21 DinB superfamily - - - 0.00000000000000000005496 96.0
HFD1_k127_6878186_22 Outer membrane lipoprotein - - - 0.000000001724 68.0
HFD1_k127_6878186_3 choline dehydrogenase activity - - - 1.604e-273 848.0
HFD1_k127_6878186_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.673e-260 820.0
HFD1_k127_6878186_5 Glycogen debranching enzyme - - - 2.605e-233 740.0
HFD1_k127_6878186_6 Amylo-alpha-1,6-glucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 631.0
HFD1_k127_6878186_7 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 550.0
HFD1_k127_6878186_8 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 461.0
HFD1_k127_6878186_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 454.0
HFD1_k127_6886378_0 Transposase is116 is110 is902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 323.0
HFD1_k127_6905088_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.023e-287 905.0
HFD1_k127_6905088_1 reverse transcriptase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 589.0
HFD1_k127_6905088_10 chlorophyll binding - - - 0.0001996 55.0
HFD1_k127_6905088_2 beta-N-acetylhexosaminidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 552.0
HFD1_k127_6905088_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 302.0
HFD1_k127_6905088_4 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000004894 266.0
HFD1_k127_6905088_5 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000001286 213.0
HFD1_k127_6905088_6 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000007812 149.0
HFD1_k127_6905088_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000002454 123.0
HFD1_k127_6905088_9 lysine biosynthesis protein LysW K05826 - - 0.00000008285 55.0
HFD1_k127_6918116_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 5.569e-293 910.0
HFD1_k127_6918116_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 5.744e-261 822.0
HFD1_k127_6918116_10 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002054 224.0
HFD1_k127_6918116_11 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001619 225.0
HFD1_k127_6918116_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000001852 229.0
HFD1_k127_6918116_13 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000004707 144.0
HFD1_k127_6918116_14 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000001919 149.0
HFD1_k127_6918116_15 Transcriptional regulator - - - 0.0000000000000000000000000000001342 128.0
HFD1_k127_6918116_16 ABC transporter K01990 - - 0.00000000000000000000000000001885 135.0
HFD1_k127_6918116_17 GAF domain - - - 0.0000000000000000000000000001047 125.0
HFD1_k127_6918116_18 Protein involved in outer membrane biogenesis K07289 - - 0.00000001074 67.0
HFD1_k127_6918116_19 Protein involved in outer membrane biogenesis K07289 - - 0.000006811 58.0
HFD1_k127_6918116_2 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 574.0
HFD1_k127_6918116_21 Cytochrome c554 and c-prime - - - 0.00004945 55.0
HFD1_k127_6918116_22 PFAM Sporulation and spore germination - - - 0.0006641 50.0
HFD1_k127_6918116_3 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 427.0
HFD1_k127_6918116_4 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 377.0
HFD1_k127_6918116_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 388.0
HFD1_k127_6918116_6 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 324.0
HFD1_k127_6918116_7 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 300.0
HFD1_k127_6918116_8 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002738 258.0
HFD1_k127_6918116_9 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000004483 261.0
HFD1_k127_69564_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 329.0
HFD1_k127_69564_1 domain protein - - - 0.000000000000000000000000000000000000000004725 166.0
HFD1_k127_6956731_0 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000001041 241.0
HFD1_k127_6959555_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.458e-197 623.0
HFD1_k127_6959555_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 334.0
HFD1_k127_6959555_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 311.0
HFD1_k127_6959555_3 Peptidase family M28 - - - 0.00000000000000000000000000000000002631 147.0
HFD1_k127_6959555_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000005745 126.0
HFD1_k127_6973021_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 437.0
HFD1_k127_6973021_1 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000006435 106.0
HFD1_k127_7009877_0 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000004518 175.0
HFD1_k127_7009877_1 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000000000000002191 126.0
HFD1_k127_7009877_2 COG NOG38524 non supervised orthologous group - - - 0.00000000000000000002779 93.0
HFD1_k127_7009877_4 - - - - 0.000000001735 64.0
HFD1_k127_7009877_5 Truncated CDS - - - 0.000000002533 60.0
HFD1_k127_7009877_6 - - - - 0.000000209 54.0
HFD1_k127_7009877_7 COG NOG20805 non supervised orthologous group - - - 0.0000002157 54.0
HFD1_k127_7009877_8 - - - - 0.00001418 50.0
HFD1_k127_7035087_0 membrane organization K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 352.0
HFD1_k127_7035087_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
HFD1_k127_7035087_2 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000000000000000000000000000005069 235.0
HFD1_k127_7035087_3 Fis family transcriptional regulator K10941 - - 0.000000000000000000000000000000000000005979 158.0
HFD1_k127_7035087_4 endopeptidase activity - - - 0.0000000000000000005025 104.0
HFD1_k127_7035087_5 Putative Ig domain - - - 0.0000000000001596 85.0
HFD1_k127_7035087_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000002227 79.0
HFD1_k127_7035087_7 Calx-beta domain - - - 0.0000005996 64.0
HFD1_k127_7035087_8 glyoxalase K01759 - 4.4.1.5 0.0002245 53.0
HFD1_k127_7035087_9 Belongs to the peptidase M10A family K01402 - 3.4.24.34 0.0005825 54.0
HFD1_k127_7036654_0 Transposase IS116/IS110/IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 347.0
HFD1_k127_7048417_0 Carboxypeptidase regulatory-like domain - - - 0.0 1054.0
HFD1_k127_7048417_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 605.0
HFD1_k127_7048417_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 484.0
HFD1_k127_7048417_3 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 417.0
HFD1_k127_7048417_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 343.0
HFD1_k127_7048417_5 oligoendopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 330.0
HFD1_k127_7048417_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000002213 183.0
HFD1_k127_7048417_7 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.0000000000000000000000000000000000000000000000002661 183.0
HFD1_k127_7048417_8 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000007118 133.0
HFD1_k127_7048417_9 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000644 98.0
HFD1_k127_70499_0 K02A2.6-like - - - 0.000000000000000000000000000000000000000000000000000001566 194.0
HFD1_k127_7069165_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 421.0
HFD1_k127_707631_0 PFAM NHL repeat - - - 6.595e-196 631.0
HFD1_k127_707631_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 301.0
HFD1_k127_707631_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001714 228.0
HFD1_k127_707631_3 AntiSigma factor - - - 0.0000000000000000000000000000000000000000007776 169.0
HFD1_k127_707631_4 DoxX-like family - - - 0.000000000000000000000000000000001083 134.0
HFD1_k127_707631_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000001298 66.0
HFD1_k127_707631_6 - - - - 0.00000001839 64.0
HFD1_k127_7112591_0 transposition - - - 1.681e-221 689.0
HFD1_k127_7174742_0 transposase activity K07483 - - 0.000000000000000000000000049 110.0
HFD1_k127_7174742_1 Integrase core domain - - - 0.0000000000000000009583 96.0
HFD1_k127_7189981_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 491.0
HFD1_k127_7189981_1 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000513 244.0
HFD1_k127_7189981_2 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000001364 228.0
HFD1_k127_7189981_3 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000002676 174.0
HFD1_k127_7189981_4 - - - - 0.0000000000000000000000001636 111.0
HFD1_k127_7207832_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000001228 119.0
HFD1_k127_7207832_1 beta-propeller repeat - - - 0.0000000000000000000000000004883 119.0
HFD1_k127_722233_0 mannose metabolic process - - - 0.000007168 48.0
HFD1_k127_7235404_0 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 336.0
HFD1_k127_7235404_1 PFAM transposase IS3 IS911 family protein - - - 0.0000000000000000000000007529 108.0
HFD1_k127_7236951_0 PFAM RibD C-terminal domain K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001266 280.0
HFD1_k127_7236951_1 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001533 223.0
HFD1_k127_7236951_2 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000000000000000000006306 211.0
HFD1_k127_7236951_3 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000002239 166.0
HFD1_k127_7236951_5 Rifampin ADP-ribosyl transferase K19062 - - 0.00000000000001656 77.0
HFD1_k127_7236951_6 Rifampin ADP-ribosyl transferase - - - 0.0000000000000855 74.0
HFD1_k127_7240778_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000002231 204.0
HFD1_k127_7245076_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 527.0
HFD1_k127_7245076_1 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 444.0
HFD1_k127_7245076_2 PFAM Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000497 260.0
HFD1_k127_7245076_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000003651 93.0
HFD1_k127_7245076_4 Transposase K07497 - - 0.0001589 49.0
HFD1_k127_7247913_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1369.0
HFD1_k127_7247913_1 Tricorn protease C1 domain K08676 - - 0.0 1052.0
HFD1_k127_7247913_10 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 459.0
HFD1_k127_7247913_11 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 399.0
HFD1_k127_7247913_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 341.0
HFD1_k127_7247913_13 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 331.0
HFD1_k127_7247913_14 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 348.0
HFD1_k127_7247913_15 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 316.0
HFD1_k127_7247913_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002342 290.0
HFD1_k127_7247913_17 Predicted Zn-dependent protease (DUF2268) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002657 282.0
HFD1_k127_7247913_18 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009823 269.0
HFD1_k127_7247913_19 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001436 237.0
HFD1_k127_7247913_2 AcrB/AcrD/AcrF family - - - 0.0 1048.0
HFD1_k127_7247913_20 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000002041 234.0
HFD1_k127_7247913_21 Glycerophosphoryl diester phosphodiesterase family K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000000005843 206.0
HFD1_k127_7247913_22 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000005316 179.0
HFD1_k127_7247913_23 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000002064 109.0
HFD1_k127_7247913_24 - - - - 0.00000000000000000001308 96.0
HFD1_k127_7247913_25 2-aminoethylphosphonate-pyruvate transaminase activity - - - 0.00000000000006192 81.0
HFD1_k127_7247913_26 Protein of unknown function (DUF2911) - - - 0.0000009237 59.0
HFD1_k127_7247913_3 MacB-like periplasmic core domain - - - 9.094e-247 787.0
HFD1_k127_7247913_4 Bacterial protein of unknown function (DUF885) - - - 4.409e-212 676.0
HFD1_k127_7247913_5 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 589.0
HFD1_k127_7247913_6 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 535.0
HFD1_k127_7247913_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 526.0
HFD1_k127_7247913_8 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 484.0
HFD1_k127_7247913_9 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 467.0
HFD1_k127_7247994_0 Cytochrome c - - - 1.031e-204 645.0
HFD1_k127_7247994_1 Reductase C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 570.0
HFD1_k127_7247994_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 574.0
HFD1_k127_7247994_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 409.0
HFD1_k127_7247994_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000004611 241.0
HFD1_k127_7247994_5 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000000000297 182.0
HFD1_k127_7247994_6 - - - - 0.000000000000000000000000000000000008032 141.0
HFD1_k127_7247994_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000002346 93.0
HFD1_k127_7250712_0 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 596.0
HFD1_k127_7250712_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 594.0
HFD1_k127_7250712_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002881 288.0
HFD1_k127_7250712_11 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
HFD1_k127_7250712_12 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007877 277.0
HFD1_k127_7250712_13 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000004857 254.0
HFD1_k127_7250712_14 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000001563 255.0
HFD1_k127_7250712_15 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000000001308 241.0
HFD1_k127_7250712_16 Probable molybdopterin binding domain K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000009544 235.0
HFD1_k127_7250712_17 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000003421 227.0
HFD1_k127_7250712_18 PFAM Peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000001817 233.0
HFD1_k127_7250712_19 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.0000000000000000000000000000000000000000000000000000000000002205 222.0
HFD1_k127_7250712_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 542.0
HFD1_k127_7250712_20 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000000000000000007536 209.0
HFD1_k127_7250712_21 PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000003295 208.0
HFD1_k127_7250712_22 Bacterial transferase hexapeptide (six repeats) K13006,K15673,K15894 - 4.2.1.115 0.00000000000000000000000000000000000000002371 162.0
HFD1_k127_7250712_23 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000001337 152.0
HFD1_k127_7250712_24 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000000000000405 145.0
HFD1_k127_7250712_25 von Willebrand factor, type A - - - 0.0000000000000000000000006042 118.0
HFD1_k127_7250712_26 Bacterial sugar transferase K19428 - - 0.000000000000000000000002427 103.0
HFD1_k127_7250712_27 - - - - 0.000000000000000000000006108 106.0
HFD1_k127_7250712_28 - - - - 0.000000000002424 74.0
HFD1_k127_7250712_29 PFAM Plasmid pRiA4b ORF-3-like protein - - - 0.00000000002419 71.0
HFD1_k127_7250712_3 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 455.0
HFD1_k127_7250712_30 pyridoxamine 5-phosphate K07005 - - 0.000000002364 64.0
HFD1_k127_7250712_31 4-amino-4-deoxy-L-arabinose transferase activity K02277 - 1.9.3.1 0.00000001969 67.0
HFD1_k127_7250712_32 deoxyhypusine monooxygenase activity - - - 0.00001877 57.0
HFD1_k127_7250712_33 Belongs to the peptidase M10A family K07761,K07999 GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241 - 0.000192 55.0
HFD1_k127_7250712_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001974 54.0
HFD1_k127_7250712_4 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 456.0
HFD1_k127_7250712_5 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 431.0
HFD1_k127_7250712_6 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 428.0
HFD1_k127_7250712_7 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 420.0
HFD1_k127_7250712_8 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 398.0
HFD1_k127_7250712_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 301.0
HFD1_k127_7258367_0 Chromatin organization modifier domain - - - 0.0000000000000000000000001577 111.0
HFD1_k127_7258367_1 Integrase core domain - - - 0.00000000001646 69.0
HFD1_k127_7272221_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 486.0
HFD1_k127_7272221_1 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 393.0
HFD1_k127_7272221_2 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 385.0
HFD1_k127_7272221_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 319.0
HFD1_k127_7272221_4 Periplasmic or secreted lipoprotein - - - 0.0000000000002525 79.0
HFD1_k127_7272221_5 Protein of unknown function (DUF1573) - - - 0.000000000211 70.0
HFD1_k127_7289995_0 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006717 273.0
HFD1_k127_7293662_0 Amino acid adenylation domain - - - 0.0 1440.0
HFD1_k127_7293662_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 9.098e-275 867.0
HFD1_k127_7293662_10 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 451.0
HFD1_k127_7293662_11 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 440.0
HFD1_k127_7293662_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 434.0
HFD1_k127_7293662_13 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 440.0
HFD1_k127_7293662_14 response regulator K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 428.0
HFD1_k127_7293662_15 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 411.0
HFD1_k127_7293662_16 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 383.0
HFD1_k127_7293662_17 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 378.0
HFD1_k127_7293662_18 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 354.0
HFD1_k127_7293662_19 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 348.0
HFD1_k127_7293662_2 acyl-CoA dehydrogenase - - - 7.245e-199 637.0
HFD1_k127_7293662_20 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 351.0
HFD1_k127_7293662_21 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 354.0
HFD1_k127_7293662_22 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 313.0
HFD1_k127_7293662_23 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 330.0
HFD1_k127_7293662_24 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 296.0
HFD1_k127_7293662_25 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 293.0
HFD1_k127_7293662_26 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 288.0
HFD1_k127_7293662_27 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003257 272.0
HFD1_k127_7293662_28 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000007022 243.0
HFD1_k127_7293662_29 Histidine kinase K02660,K03406,K11525 - - 0.000000000000000000000000000000000000000000000000000000000000000001882 256.0
HFD1_k127_7293662_3 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 578.0
HFD1_k127_7293662_30 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000008506 236.0
HFD1_k127_7293662_31 WD40-like Beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000001692 231.0
HFD1_k127_7293662_32 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000002699 225.0
HFD1_k127_7293662_33 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000001836 219.0
HFD1_k127_7293662_34 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000002434 212.0
HFD1_k127_7293662_35 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000007368 222.0
HFD1_k127_7293662_36 Zn-dependent hydrolase, glyoxylase - - - 0.0000000000000000000000000000000000000000000000000000009854 204.0
HFD1_k127_7293662_37 Bacterial regulatory proteins, tetR family K13770 - - 0.00000000000000000000000000000000000000000000000002265 186.0
HFD1_k127_7293662_38 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000816 181.0
HFD1_k127_7293662_39 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000007044 182.0
HFD1_k127_7293662_4 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 550.0
HFD1_k127_7293662_40 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000002046 179.0
HFD1_k127_7293662_41 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.0000000000000000000000000000000000000007075 158.0
HFD1_k127_7293662_42 PhoQ Sensor - - - 0.000000000000000000000000000000000000001428 170.0
HFD1_k127_7293662_43 PFAM MscS Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000005331 153.0
HFD1_k127_7293662_44 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000006749 152.0
HFD1_k127_7293662_45 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000006939 154.0
HFD1_k127_7293662_46 nucleotide catabolic process - - - 0.000000000000000000000000000000000006975 152.0
HFD1_k127_7293662_47 outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000111 143.0
HFD1_k127_7293662_48 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000007714 143.0
HFD1_k127_7293662_49 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000005655 129.0
HFD1_k127_7293662_5 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 535.0
HFD1_k127_7293662_50 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000001623 121.0
HFD1_k127_7293662_51 Single cache domain 3 - - - 0.0000000000000000000000000003143 127.0
HFD1_k127_7293662_52 protein-glutamate methylesterase activity K03412,K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.000000000000000000000000001354 119.0
HFD1_k127_7293662_53 von Willebrand factor, type A K07114 - - 0.000000000000000000000000001408 126.0
HFD1_k127_7293662_54 Response regulator receiver domain K03413 - - 0.00000000000000000000000001446 113.0
HFD1_k127_7293662_55 lytic transglycosylase activity K03194 - - 0.000000000000000000000005474 116.0
HFD1_k127_7293662_56 Chemotaxis protein CheX K03409 - - 0.00000000000000000000002415 105.0
HFD1_k127_7293662_57 Outer membrane lipoprotein - - - 0.000000000000000000000076 108.0
HFD1_k127_7293662_58 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000007413 90.0
HFD1_k127_7293662_59 Phospholipase_D-nuclease N-terminal - - - 0.000000000000001142 80.0
HFD1_k127_7293662_6 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 508.0
HFD1_k127_7293662_60 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000005622 61.0
HFD1_k127_7293662_61 energy transducer activity K03646,K03832 - - 0.0000001913 62.0
HFD1_k127_7293662_62 Domain of unknown function (DUF4388) - - - 0.0005108 52.0
HFD1_k127_7293662_7 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 493.0
HFD1_k127_7293662_8 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 462.0
HFD1_k127_7293662_9 ABC transporter, solute-binding protein K11069,K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 467.0
HFD1_k127_7296582_0 PFAM Alcohol dehydrogenase GroES-like - - - 4.655e-200 628.0
HFD1_k127_7296582_1 PFAM Ribonuclease BN-like family K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 332.0
HFD1_k127_7296582_2 - - - - 0.000000000000000000000000000000000000000000000000000000002142 213.0
HFD1_k127_7296582_3 Transposase K07491 - - 0.000000000000000000000000000000000139 141.0
HFD1_k127_7296582_4 sequence-specific DNA binding - - - 0.000000000000000000000003942 102.0
HFD1_k127_7297536_0 MacB-like periplasmic core domain - - - 1.14e-278 883.0
HFD1_k127_7297536_1 - - - - 9.332e-219 702.0
HFD1_k127_7297536_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000004339 212.0
HFD1_k127_7297536_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000002783 183.0
HFD1_k127_7297536_4 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000584 119.0
HFD1_k127_7297536_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000134 100.0
HFD1_k127_7297536_6 Cytochrome c class I - - - 0.00000000004476 70.0
HFD1_k127_73039_0 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000001056 228.0
HFD1_k127_7309677_0 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 341.0
HFD1_k127_7309677_1 - - - - 0.000000000000000000000000000000000000000000005993 175.0
HFD1_k127_7309677_2 Peptidase family C25 - - - 0.00000000000000000000000000000001429 136.0
HFD1_k127_7309677_3 Polysaccharide export protein K01991,K20988 - - 0.00000000000000000000000000001674 132.0
HFD1_k127_7309677_5 Tetratricopeptide repeat - - - 0.000000000000006083 88.0
HFD1_k127_7309677_6 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0003116 44.0
HFD1_k127_7317397_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1050.0
HFD1_k127_7317397_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 4.252e-268 834.0
HFD1_k127_7317397_10 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 525.0
HFD1_k127_7317397_11 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 482.0
HFD1_k127_7317397_12 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 456.0
HFD1_k127_7317397_13 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 461.0
HFD1_k127_7317397_14 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 419.0
HFD1_k127_7317397_15 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 411.0
HFD1_k127_7317397_16 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 411.0
HFD1_k127_7317397_17 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 399.0
HFD1_k127_7317397_18 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 381.0
HFD1_k127_7317397_19 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 377.0
HFD1_k127_7317397_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.093e-252 798.0
HFD1_k127_7317397_20 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 355.0
HFD1_k127_7317397_21 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 355.0
HFD1_k127_7317397_22 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 351.0
HFD1_k127_7317397_23 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 348.0
HFD1_k127_7317397_24 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 336.0
HFD1_k127_7317397_25 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 301.0
HFD1_k127_7317397_26 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008306 276.0
HFD1_k127_7317397_27 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003653 263.0
HFD1_k127_7317397_28 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000001518 204.0
HFD1_k127_7317397_29 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000113 193.0
HFD1_k127_7317397_3 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 1.098e-246 782.0
HFD1_k127_7317397_30 Endoribonuclease L-PSP K09021,K09022 GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.99.10 0.000000000000000000000000000000000000000000002251 169.0
HFD1_k127_7317397_31 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000002038 166.0
HFD1_k127_7317397_32 methyltransferase activity - - - 0.0000000000000000000000000000000000000001031 155.0
HFD1_k127_7317397_33 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000000000000000000000001597 153.0
HFD1_k127_7317397_34 Glycosyl transferase family 2 - - - 0.000000000000000000000000000004716 131.0
HFD1_k127_7317397_35 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000001576 117.0
HFD1_k127_7317397_36 TIGRFAM TonB K03832 - - 0.000000000000000000000004471 112.0
HFD1_k127_7317397_37 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.00000000000000000000002994 103.0
HFD1_k127_7317397_38 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000003389 100.0
HFD1_k127_7317397_39 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000001446 92.0
HFD1_k127_7317397_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 605.0
HFD1_k127_7317397_40 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000007349 86.0
HFD1_k127_7317397_41 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.0000000000000007633 90.0
HFD1_k127_7317397_42 von Willebrand factor, type A - - - 0.000000000000004821 87.0
HFD1_k127_7317397_43 Tetratricopeptide repeat - - - 0.00000000002155 74.0
HFD1_k127_7317397_44 gluconolactonase activity K13276,K13735,K14274 GO:0005575,GO:0005576 - 0.0000003016 61.0
HFD1_k127_7317397_45 Rhodanese Homology Domain - - - 0.000001909 56.0
HFD1_k127_7317397_46 PFAM glycosyl transferase family 9 - - - 0.000002939 59.0
HFD1_k127_7317397_47 Peptidase M16 inactive domain K07263 - - 0.0008049 50.0
HFD1_k127_7317397_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 589.0
HFD1_k127_7317397_6 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 596.0
HFD1_k127_7317397_7 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 590.0
HFD1_k127_7317397_8 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007574 565.0
HFD1_k127_7317397_9 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 546.0
HFD1_k127_7318103_0 DEAD DEAH box helicase K03724 - - 0.0 1739.0
HFD1_k127_7318103_1 metallocarboxypeptidase activity K14054 - - 0.0 1199.0
HFD1_k127_7318103_10 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 550.0
HFD1_k127_7318103_11 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 498.0
HFD1_k127_7318103_12 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 467.0
HFD1_k127_7318103_13 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 424.0
HFD1_k127_7318103_14 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 424.0
HFD1_k127_7318103_15 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 418.0
HFD1_k127_7318103_16 Sigma-54 interaction domain K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 449.0
HFD1_k127_7318103_17 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 404.0
HFD1_k127_7318103_18 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 385.0
HFD1_k127_7318103_19 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 330.0
HFD1_k127_7318103_2 Serine Threonine protein kinase - - - 0.0 1173.0
HFD1_k127_7318103_20 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 322.0
HFD1_k127_7318103_21 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 327.0
HFD1_k127_7318103_22 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005492 249.0
HFD1_k127_7318103_23 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000002952 251.0
HFD1_k127_7318103_24 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000005899 242.0
HFD1_k127_7318103_25 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000003416 227.0
HFD1_k127_7318103_26 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000009344 217.0
HFD1_k127_7318103_27 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000001883 208.0
HFD1_k127_7318103_28 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000733 199.0
HFD1_k127_7318103_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000008682 192.0
HFD1_k127_7318103_3 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 6.622e-314 974.0
HFD1_k127_7318103_30 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000004861 190.0
HFD1_k127_7318103_31 dehydratase - - - 0.000000000000000000000000000000000000000000000001104 179.0
HFD1_k127_7318103_32 TspO/MBR family - - - 0.00000000000000000000000000000000000000000000001165 175.0
HFD1_k127_7318103_33 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000001184 184.0
HFD1_k127_7318103_34 - - - - 0.000000000000000000000000000000000000000000002455 169.0
HFD1_k127_7318103_35 dehydratase - - - 0.00000000000000000000000000000000000000000001539 172.0
HFD1_k127_7318103_36 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000001342 161.0
HFD1_k127_7318103_38 Haem-degrading - - - 0.0000000000000000000000000000000000008323 145.0
HFD1_k127_7318103_39 - - - - 0.000000000000000000000000000000005292 134.0
HFD1_k127_7318103_4 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 1.182e-301 940.0
HFD1_k127_7318103_40 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000001047 124.0
HFD1_k127_7318103_41 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000003444 126.0
HFD1_k127_7318103_42 - - - - 0.000000000000001657 81.0
HFD1_k127_7318103_43 F420H(2)-dependent quinone reductase - - - 0.00000000000006359 76.0
HFD1_k127_7318103_44 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000815 79.0
HFD1_k127_7318103_45 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000009745 81.0
HFD1_k127_7318103_46 AntiSigma factor - - - 0.0005435 52.0
HFD1_k127_7318103_5 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 2.625e-261 832.0
HFD1_k127_7318103_6 Peptidase S46 - - - 3.182e-234 745.0
HFD1_k127_7318103_7 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 9.563e-206 657.0
HFD1_k127_7318103_8 PFAM NAD-dependent epimerase dehydratase - - - 1.427e-203 644.0
HFD1_k127_7318103_9 gluconolactonase activity K01053 - 3.1.1.17 1.701e-194 622.0
HFD1_k127_7320371_0 Fibronectin type III-like domain K05349 - 3.2.1.21 7.523e-301 941.0
HFD1_k127_7320371_1 Pfam Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 1.582e-194 617.0
HFD1_k127_7320371_2 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000001686 212.0
HFD1_k127_7321969_0 Polysulphide reductase, NrfD K00185 - - 1.257e-224 703.0
HFD1_k127_7321969_1 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009433 243.0
HFD1_k127_7321969_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000008431 228.0
HFD1_k127_7321969_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000001822 166.0
HFD1_k127_7322279_0 Response regulator receiver domain - - - 0.0 1918.0
HFD1_k127_7322279_1 PFAM Conserved region in glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1502.0
HFD1_k127_7322279_10 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 476.0
HFD1_k127_7322279_11 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 479.0
HFD1_k127_7322279_12 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 398.0
HFD1_k127_7322279_13 PFAM CheR methyltransferase, SAM binding domain K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 305.0
HFD1_k127_7322279_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005091 254.0
HFD1_k127_7322279_15 DinB family - - - 0.00000000000000000000000000000000000000000000000000001042 198.0
HFD1_k127_7322279_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000001007 156.0
HFD1_k127_7322279_17 Calcium/calmodulin dependent protein kinase II association domain - - - 0.00000000000000000000000000000000001441 141.0
HFD1_k127_7322279_18 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000002454 104.0
HFD1_k127_7322279_19 RNA recognition motif - - - 0.00000000000000000003019 93.0
HFD1_k127_7322279_2 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1250.0
HFD1_k127_7322279_20 PFAM Transcription factor CarD K07736 - - 0.00000000005233 70.0
HFD1_k127_7322279_3 Dehydrogenase E1 component K11381 - 1.2.4.4 2.234e-289 905.0
HFD1_k127_7322279_4 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 2.18e-239 754.0
HFD1_k127_7322279_5 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 7.026e-233 738.0
HFD1_k127_7322279_6 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 1.334e-225 709.0
HFD1_k127_7322279_7 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 6.271e-214 674.0
HFD1_k127_7322279_8 Ammonium Transporter K03320 - - 2.695e-195 620.0
HFD1_k127_7322279_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 518.0
HFD1_k127_7337902_0 Protein of unknown function, DUF255 K06888 - - 2.548e-243 769.0
HFD1_k127_7337902_1 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 6.879e-208 659.0
HFD1_k127_7337902_10 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 396.0
HFD1_k127_7337902_11 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 378.0
HFD1_k127_7337902_12 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 360.0
HFD1_k127_7337902_13 Acts as a magnesium transporter K03281,K04767,K06213,K15986 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 319.0
HFD1_k127_7337902_14 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 294.0
HFD1_k127_7337902_15 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 301.0
HFD1_k127_7337902_16 integrase domain protein SAM domain protein K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 295.0
HFD1_k127_7337902_17 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008856 283.0
HFD1_k127_7337902_18 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003557 273.0
HFD1_k127_7337902_19 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000002901 241.0
HFD1_k127_7337902_2 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 600.0
HFD1_k127_7337902_20 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000009362 230.0
HFD1_k127_7337902_21 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000004623 223.0
HFD1_k127_7337902_22 tigr00255 - - - 0.0000000000000000000000000000000000000000000000000000000000009916 220.0
HFD1_k127_7337902_23 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000472 220.0
HFD1_k127_7337902_24 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000002361 225.0
HFD1_k127_7337902_25 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000001796 205.0
HFD1_k127_7337902_26 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000001869 189.0
HFD1_k127_7337902_27 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000002147 191.0
HFD1_k127_7337902_28 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000009679 187.0
HFD1_k127_7337902_29 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000002084 171.0
HFD1_k127_7337902_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 561.0
HFD1_k127_7337902_30 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000000002467 177.0
HFD1_k127_7337902_31 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000006819 170.0
HFD1_k127_7337902_32 YHS domain K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000009494 166.0
HFD1_k127_7337902_33 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000005552 158.0
HFD1_k127_7337902_34 Protein of unknown function (DUF2834) - - - 0.000000000000000000000000000000000000000559 152.0
HFD1_k127_7337902_35 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000007174 140.0
HFD1_k127_7337902_36 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000003381 136.0
HFD1_k127_7337902_37 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000000000000006979 133.0
HFD1_k127_7337902_38 Domain of unknown function (DUF4112) - - - 0.000000000000000000000001429 109.0
HFD1_k127_7337902_39 Cupin domain - - - 0.000000000000000000000003498 106.0
HFD1_k127_7337902_4 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 541.0
HFD1_k127_7337902_40 transcriptional regulator - - - 0.00000000000000000002444 99.0
HFD1_k127_7337902_41 peroxiredoxin activity K03564 - 1.11.1.15 0.0000000000000000000344 93.0
HFD1_k127_7337902_43 Tetratricopeptide repeat - - - 0.00000000000000001194 97.0
HFD1_k127_7337902_44 multi-organism process - - - 0.0000000000000001592 94.0
HFD1_k127_7337902_45 - - - - 0.000000000000001244 80.0
HFD1_k127_7337902_47 YbbR-like protein - - - 0.00000000000001607 84.0
HFD1_k127_7337902_48 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000004535 74.0
HFD1_k127_7337902_49 NAD(P)-dependent K07119 - - 0.0000000000002022 72.0
HFD1_k127_7337902_5 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 478.0
HFD1_k127_7337902_50 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000002436 52.0
HFD1_k127_7337902_51 Peptidoglycan-binding domain 1 protein - - - 0.00002085 55.0
HFD1_k127_7337902_52 - - - - 0.0001064 53.0
HFD1_k127_7337902_53 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000611 46.0
HFD1_k127_7337902_6 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 461.0
HFD1_k127_7337902_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 413.0
HFD1_k127_7337902_8 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 392.0
HFD1_k127_7337902_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 389.0
HFD1_k127_7338792_0 cellulose binding - - - 0.0 1383.0
HFD1_k127_7338792_1 Tetratricopeptide repeat K12132 - 2.7.11.1 2.317e-271 893.0
HFD1_k127_7338792_10 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000001886 141.0
HFD1_k127_7338792_11 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000008057 134.0
HFD1_k127_7338792_12 BMC - - - 0.00000000000000000000000000000000147 134.0
HFD1_k127_7338792_13 Thioesterase superfamily - - - 0.000000000000000000000000000003017 124.0
HFD1_k127_7338792_14 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000001947 113.0
HFD1_k127_7338792_15 - - - - 0.000000000000000002654 89.0
HFD1_k127_7338792_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 1.009e-196 629.0
HFD1_k127_7338792_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 499.0
HFD1_k127_7338792_4 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 375.0
HFD1_k127_7338792_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 293.0
HFD1_k127_7338792_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 293.0
HFD1_k127_7338792_7 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000003706 241.0
HFD1_k127_7338792_8 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000583 226.0
HFD1_k127_7338792_9 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000005903 210.0
HFD1_k127_7343655_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 383.0
HFD1_k127_7343655_1 - - - - 0.00000000000000000003025 96.0
HFD1_k127_7343655_2 Belongs to the metal hydrolase YfiT family - - - 0.00007884 45.0
HFD1_k127_7372326_0 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 567.0
HFD1_k127_7372326_1 Oxidoreductase family, C-terminal alpha beta domain K00118,K13020 - 1.1.1.335,1.1.99.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 484.0
HFD1_k127_7372326_2 Domain of unknown function (DUF4118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 489.0
HFD1_k127_7372326_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 368.0
HFD1_k127_7372326_5 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000007829 181.0
HFD1_k127_7372326_6 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000002051 153.0
HFD1_k127_7372326_7 Protein of unknown function (DUF3309) - - - 0.00000000000000003491 87.0
HFD1_k127_7372326_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000001543 61.0
HFD1_k127_7372326_9 Rhodanese domain protein - - - 0.00000001019 57.0
HFD1_k127_7386_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009974 487.0
HFD1_k127_7386_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 451.0
HFD1_k127_7386_10 RDD family - - - 0.0000000001224 74.0
HFD1_k127_7386_11 sequence-specific DNA binding - - - 0.00000002615 62.0
HFD1_k127_7386_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 425.0
HFD1_k127_7386_3 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 400.0
HFD1_k127_7386_4 undecaprenyl-diphosphatase activity K06153 GO:0006950,GO:0008150,GO:0050896,GO:0051409 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 287.0
HFD1_k127_7386_5 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003126 284.0
HFD1_k127_7386_6 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000002957 220.0
HFD1_k127_7386_7 response regulator - - - 0.000000000000000000000000000000000000000000000000000000001882 209.0
HFD1_k127_7386_8 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000001422 203.0
HFD1_k127_7386_9 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000004538 146.0
HFD1_k127_7391924_0 K02A2.6-like - - - 7.551e-271 877.0
HFD1_k127_7392430_0 microtubule motor activity K02988,K10403 GO:0000070,GO:0000278,GO:0000280,GO:0000775,GO:0000776,GO:0000785,GO:0000819,GO:0000902,GO:0000904,GO:0001654,GO:0001756,GO:0001966,GO:0002376,GO:0002478,GO:0002495,GO:0002504,GO:0003002,GO:0003674,GO:0003676,GO:0003677,GO:0003774,GO:0003777,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005819,GO:0005829,GO:0005856,GO:0005871,GO:0005875,GO:0006810,GO:0006890,GO:0006928,GO:0006996,GO:0007017,GO:0007018,GO:0007049,GO:0007059,GO:0007062,GO:0007080,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007417,GO:0007420,GO:0007423,GO:0008150,GO:0009605,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009952,GO:0009987,GO:0015630,GO:0016043,GO:0016192,GO:0016462,GO:0016604,GO:0016607,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019882,GO:0019884,GO:0019886,GO:0021952,GO:0021953,GO:0021954,GO:0021955,GO:0022008,GO:0022402,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0032991,GO:0035282,GO:0040011,GO:0042330,GO:0043009,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0048002,GO:0048193,GO:0048285,GO:0048468,GO:0048513,GO:0048592,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050000,GO:0050896,GO:0051179,GO:0051234,GO:0051276,GO:0051303,GO:0051310,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0060322,GO:0060429,GO:0061053,GO:0061564,GO:0070013,GO:0071840,GO:0072686,GO:0090596,GO:0097159,GO:0098687,GO:0098813,GO:0120036,GO:0120039,GO:0140014,GO:1901363,GO:1903047 - 0.000000000000000000000000000001375 123.0
HFD1_k127_7392430_1 Ribonuclease H protein - - - 0.000000002614 65.0
HFD1_k127_7396239_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 443.0
HFD1_k127_7407277_0 Polysulphide reductase, NrfD - - - 7.317e-205 647.0
HFD1_k127_7407277_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 579.0
HFD1_k127_7407277_2 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 374.0
HFD1_k127_7407277_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 351.0
HFD1_k127_7407277_4 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 353.0
HFD1_k127_7407277_5 PFAM cytoplasmic chaperone TorD family protein - - - 0.00000000000000002605 90.0
HFD1_k127_7407277_6 DisA bacterial checkpoint controller nucleotide-binding - - - 0.0000682 47.0
HFD1_k127_7410872_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 1.474e-218 716.0
HFD1_k127_7410872_1 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 544.0
HFD1_k127_7410872_10 Smr domain - - - 0.0000000000000000000000000005284 119.0
HFD1_k127_7410872_12 Protein of unknown function (DUF1573) - - - 0.0001056 46.0
HFD1_k127_7410872_13 Belongs to the 'phage' integrase family - - - 0.0001769 49.0
HFD1_k127_7410872_14 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0002416 44.0
HFD1_k127_7410872_2 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 353.0
HFD1_k127_7410872_3 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 343.0
HFD1_k127_7410872_4 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 321.0
HFD1_k127_7410872_5 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004013 249.0
HFD1_k127_7410872_6 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000007617 198.0
HFD1_k127_7410872_7 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000002111 194.0
HFD1_k127_7410872_8 PQQ enzyme repeat - - - 0.0000000000000000000000000001104 130.0
HFD1_k127_7410872_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000001236 132.0
HFD1_k127_7412638_0 Gypsy retrotransposon - - - 0.0000000000000000000000000000000001188 151.0
HFD1_k127_7414132_0 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 576.0
HFD1_k127_7414132_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000103 187.0
HFD1_k127_7414132_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000001152 158.0
HFD1_k127_7414132_3 Fatty acid desaturase - - - 0.000000000000000000007215 105.0
HFD1_k127_7414132_5 Pkd domain containing protein - - - 0.0003777 48.0
HFD1_k127_7427614_0 Protein tyrosine kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002364 234.0
HFD1_k127_7440784_0 von Willebrand factor (vWF) type A domain - - - 8.524e-250 808.0
HFD1_k127_7440784_1 von Willebrand factor (vWF) type A domain - - - 1.617e-197 657.0
HFD1_k127_7440784_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003611 298.0
HFD1_k127_7440784_3 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000006399 134.0
HFD1_k127_7440784_4 Putative glucoamylase - - - 0.000000000000008436 77.0
HFD1_k127_7457967_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.47e-197 622.0
HFD1_k127_7457967_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 471.0
HFD1_k127_7466706_0 COG2931 RTX toxins and related Ca2 -binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001271 273.0
HFD1_k127_7486402_0 GTP-binding protein TypA K06207 - - 3.772e-266 839.0
HFD1_k127_7486402_1 ASPIC and UnbV - - - 4.364e-256 800.0
HFD1_k127_7486402_10 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 336.0
HFD1_k127_7486402_11 PFAM intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 304.0
HFD1_k127_7486402_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 317.0
HFD1_k127_7486402_13 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 301.0
HFD1_k127_7486402_14 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002822 269.0
HFD1_k127_7486402_15 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002244 259.0
HFD1_k127_7486402_16 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003941 260.0
HFD1_k127_7486402_17 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000833 260.0
HFD1_k127_7486402_18 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000002878 251.0
HFD1_k127_7486402_19 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001279 250.0
HFD1_k127_7486402_2 PFAM Magnesium chelatase, ChlI subunit K07391 - - 1.278e-222 700.0
HFD1_k127_7486402_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000003685 236.0
HFD1_k127_7486402_21 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000003933 228.0
HFD1_k127_7486402_22 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000001363 225.0
HFD1_k127_7486402_23 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000402 219.0
HFD1_k127_7486402_24 GAF domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000001812 214.0
HFD1_k127_7486402_25 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000001309 199.0
HFD1_k127_7486402_26 DinB superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000007114 188.0
HFD1_k127_7486402_27 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000001206 183.0
HFD1_k127_7486402_28 - - - - 0.000000000000000000000000000000000000000000139 173.0
HFD1_k127_7486402_29 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000004427 162.0
HFD1_k127_7486402_3 peptidyl-tyrosine sulfation - - - 1.464e-219 696.0
HFD1_k127_7486402_30 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000003835 159.0
HFD1_k127_7486402_31 von Willebrand factor, type A - - - 0.00000000000000000000000000000007126 145.0
HFD1_k127_7486402_32 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000008223 133.0
HFD1_k127_7486402_33 PFAM Transposase IS200 like K07491 - - 0.0000000000000000000000000006838 117.0
HFD1_k127_7486402_34 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000001303 124.0
HFD1_k127_7486402_35 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000000001005 109.0
HFD1_k127_7486402_36 PAP2 superfamily - - - 0.00000000000000000000007884 110.0
HFD1_k127_7486402_37 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000009142 90.0
HFD1_k127_7486402_38 Domain of unknown function (DUF4149) - - - 0.00000000000000003236 88.0
HFD1_k127_7486402_39 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00000000000008181 74.0
HFD1_k127_7486402_4 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 627.0
HFD1_k127_7486402_40 ABC-type transport system involved in multi-copper enzyme maturation - - - 0.000000000000782 74.0
HFD1_k127_7486402_41 COG3209 Rhs family protein - - - 0.0000000001278 72.0
HFD1_k127_7486402_42 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000003144 70.0
HFD1_k127_7486402_43 PFAM Na dependent nucleoside transporter K03317 - - 0.0000005619 53.0
HFD1_k127_7486402_5 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 611.0
HFD1_k127_7486402_6 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 551.0
HFD1_k127_7486402_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 514.0
HFD1_k127_7486402_8 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 397.0
HFD1_k127_7486402_9 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 357.0
HFD1_k127_7534619_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009406 255.0
HFD1_k127_7534619_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000003426 181.0
HFD1_k127_7534619_2 Phosphoglycerate mutase family K03574 - 3.6.1.55 0.000000000000000000000001536 109.0
HFD1_k127_7537723_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 522.0
HFD1_k127_7538309_0 - - - - 0.0008193 51.0
HFD1_k127_7572118_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 564.0
HFD1_k127_7572118_1 Surface antigen - - - 0.0000000002122 66.0
HFD1_k127_7584917_0 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 483.0
HFD1_k127_7590258_0 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 477.0
HFD1_k127_7590258_1 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 385.0
HFD1_k127_7590258_2 COGs COG0463 Glycosyltransferase involved in cell wall biogenesis K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 294.0
HFD1_k127_7590258_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 264.0
HFD1_k127_7590258_4 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000001028 177.0
HFD1_k127_76085_0 serine-type peptidase activity - - - 0.0 1118.0
HFD1_k127_76085_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.102e-311 995.0
HFD1_k127_76085_10 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 323.0
HFD1_k127_76085_11 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 342.0
HFD1_k127_76085_12 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 321.0
HFD1_k127_76085_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 326.0
HFD1_k127_76085_14 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000635 284.0
HFD1_k127_76085_15 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000819 279.0
HFD1_k127_76085_16 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001 242.0
HFD1_k127_76085_17 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000001337 181.0
HFD1_k127_76085_18 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000001798 169.0
HFD1_k127_76085_19 Thioredoxin domain - - - 0.00000000000000000000000000000000000000008246 156.0
HFD1_k127_76085_2 MacB-like periplasmic core domain - - - 7.163e-237 761.0
HFD1_k127_76085_20 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000004461 149.0
HFD1_k127_76085_21 - - - - 0.0000000000000000000000000000000000001936 145.0
HFD1_k127_76085_22 Thioesterase superfamily K07107 - - 0.00000000000000000000816 97.0
HFD1_k127_76085_23 Thioredoxin domain - - - 0.000000000000000001221 87.0
HFD1_k127_76085_24 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000002438 91.0
HFD1_k127_76085_25 - - - - 0.000000000000000274 89.0
HFD1_k127_76085_26 - - - - 0.00000000000003338 76.0
HFD1_k127_76085_27 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000007796 80.0
HFD1_k127_76085_28 Ribosome-associated heat shock protein implicated in recycling of 50S subunit - - - 0.0000000000007804 73.0
HFD1_k127_76085_29 - - - - 0.0000000000009285 72.0
HFD1_k127_76085_3 Acyl-coa dehydrogenase K00249 - 1.3.8.7 1.094e-199 628.0
HFD1_k127_76085_30 Glycosyl hydrolase family 26 - - - 0.0000002191 60.0
HFD1_k127_76085_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 569.0
HFD1_k127_76085_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 506.0
HFD1_k127_76085_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 508.0
HFD1_k127_76085_7 - K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 484.0
HFD1_k127_76085_8 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 472.0
HFD1_k127_76085_9 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 445.0
HFD1_k127_7611116_0 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 390.0
HFD1_k127_7611116_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008852 272.0
HFD1_k127_7663885_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 5.813e-278 887.0
HFD1_k127_7663885_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 2.358e-255 821.0
HFD1_k127_7663885_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000007559 109.0
HFD1_k127_7663885_11 - - - - 0.0000000008555 69.0
HFD1_k127_7663885_2 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 358.0
HFD1_k127_7663885_3 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000008455 248.0
HFD1_k127_7663885_4 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000007031 235.0
HFD1_k127_7663885_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000003593 228.0
HFD1_k127_7663885_6 SNARE associated Golgi protein K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000172 169.0
HFD1_k127_7663885_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.0000000000000000000000000000000000000000002974 176.0
HFD1_k127_7663885_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000001923 157.0
HFD1_k127_7663885_9 outer membrane efflux protein - - - 0.000000000000000000000000000001315 138.0
HFD1_k127_7684316_0 - - - - 0.00000000000000000000000000000000001683 137.0
HFD1_k127_7684316_1 - - - - 0.00000000000000000000000000009019 117.0
HFD1_k127_7684316_2 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000000000002581 111.0
HFD1_k127_7684316_3 - - - - 0.00000000000000000000003997 103.0
HFD1_k127_7684316_4 - - - - 0.000000000000000001016 86.0
HFD1_k127_7684316_9 - - - - 0.00009202 45.0
HFD1_k127_7687963_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009535 253.0
HFD1_k127_7687963_1 Transposase - - - 0.00008383 51.0
HFD1_k127_77402_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 462.0
HFD1_k127_77402_1 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000051 237.0
HFD1_k127_77402_2 PBS lyase HEAT-like repeat - - - 0.00000000000000000000006801 105.0
HFD1_k127_77402_3 Zinc metalloprotease (Elastase) K20274 - - 0.000008774 50.0
HFD1_k127_77402_4 peptidase S9 - - - 0.0000924 48.0
HFD1_k127_7790503_0 - - - - 0.000000000000000000000000000000000000000000000001999 181.0
HFD1_k127_7790503_1 - - - - 0.00000000000000000000000000000000000000000000003105 178.0
HFD1_k127_7790503_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000001502 99.0
HFD1_k127_7790503_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000007817 93.0
HFD1_k127_7790503_4 Peptidase dimerisation domain K12941 - - 0.0005102 43.0
HFD1_k127_7790610_0 Hydrolase CocE NonD family - - - 0.0 1009.0
HFD1_k127_7790610_1 Putative diguanylate phosphodiesterase - - - 1.28e-208 672.0
HFD1_k127_7790610_10 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 390.0
HFD1_k127_7790610_11 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 378.0
HFD1_k127_7790610_12 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 380.0
HFD1_k127_7790610_13 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 354.0
HFD1_k127_7790610_14 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 352.0
HFD1_k127_7790610_15 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 305.0
HFD1_k127_7790610_16 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 311.0
HFD1_k127_7790610_17 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 309.0
HFD1_k127_7790610_18 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002885 260.0
HFD1_k127_7790610_19 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000005516 243.0
HFD1_k127_7790610_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 548.0
HFD1_k127_7790610_20 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000392 210.0
HFD1_k127_7790610_21 cytochrome - - - 0.0000000000000000000000000000000000000000000002308 172.0
HFD1_k127_7790610_22 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000005464 159.0
HFD1_k127_7790610_23 CYTH - - - 0.00000002246 66.0
HFD1_k127_7790610_3 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 529.0
HFD1_k127_7790610_4 5'-3' exonuclease, N-terminal resolvase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 460.0
HFD1_k127_7790610_5 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 469.0
HFD1_k127_7790610_6 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 472.0
HFD1_k127_7790610_7 magnesium chelatase K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 434.0
HFD1_k127_7790610_8 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 432.0
HFD1_k127_7790610_9 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 389.0
HFD1_k127_7795826_0 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000007528 253.0
HFD1_k127_7795826_1 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000938 123.0
HFD1_k127_7797469_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003019 266.0
HFD1_k127_7797469_1 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000002883 192.0
HFD1_k127_7850678_0 protein phosphatase regulator activity K13506,K15407 - 2.3.1.15,2.4.2.29 7.105e-231 751.0
HFD1_k127_7852058_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 617.0
HFD1_k127_7852058_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 498.0
HFD1_k127_7852058_10 Protein of unknown function (DUF2911) - - - 0.00000000006855 69.0
HFD1_k127_7852058_11 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.0000000006683 72.0
HFD1_k127_7852058_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 436.0
HFD1_k127_7852058_3 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 419.0
HFD1_k127_7852058_4 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 344.0
HFD1_k127_7852058_5 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001103 281.0
HFD1_k127_7852058_6 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.0000000000000000000000000000000000000000000000000000000000000000003318 243.0
HFD1_k127_7852058_7 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000001015 216.0
HFD1_k127_7852058_9 CAAX protease self-immunity K07052 - - 0.00000000000000000000001368 109.0
HFD1_k127_7857426_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 413.0
HFD1_k127_7857426_1 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 332.0
HFD1_k127_7857426_2 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 304.0
HFD1_k127_7857426_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000005021 201.0
HFD1_k127_7857426_4 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000002895 119.0
HFD1_k127_7857426_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000007098 74.0
HFD1_k127_7883607_0 SPTR Transposase IS4 family - - - 0.0000000000000000000000000000000000000002593 158.0
HFD1_k127_7883607_1 Xaa-His dipeptidase K01270 - - 0.0000000000000000003432 89.0
HFD1_k127_7911859_0 Carboxyl transferase domain - - - 3.714e-226 713.0
HFD1_k127_7911859_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.966e-218 695.0
HFD1_k127_7911859_10 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 363.0
HFD1_k127_7911859_11 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 305.0
HFD1_k127_7911859_12 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001744 280.0
HFD1_k127_7911859_13 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000238 207.0
HFD1_k127_7911859_14 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000007385 172.0
HFD1_k127_7911859_15 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000163 184.0
HFD1_k127_7911859_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000007169 143.0
HFD1_k127_7911859_17 Penicillinase repressor - - - 0.0000000000000000000000000000000002621 136.0
HFD1_k127_7911859_18 PDZ DHR GLGF domain protein - - - 0.00000000000000000000005023 111.0
HFD1_k127_7911859_19 Putative adhesin - - - 0.0000000000000007859 89.0
HFD1_k127_7911859_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.261e-213 678.0
HFD1_k127_7911859_20 - - - - 0.000000000000004159 85.0
HFD1_k127_7911859_21 Domain of unknown function (DUF4956) - - - 0.0000000008562 68.0
HFD1_k127_7911859_22 energy transducer activity K03832 - - 0.000000004325 70.0
HFD1_k127_7911859_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 563.0
HFD1_k127_7911859_4 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 513.0
HFD1_k127_7911859_5 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 430.0
HFD1_k127_7911859_6 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 396.0
HFD1_k127_7911859_7 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 402.0
HFD1_k127_7911859_8 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 388.0
HFD1_k127_7911859_9 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 381.0
HFD1_k127_7918973_0 Amino acid permease - - - 9.37e-251 795.0
HFD1_k127_7918973_1 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 527.0
HFD1_k127_7918973_10 amine dehydrogenase activity - - - 0.000000000085 77.0
HFD1_k127_7918973_11 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00006358 54.0
HFD1_k127_7918973_2 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 390.0
HFD1_k127_7918973_3 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004799 286.0
HFD1_k127_7918973_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000004788 237.0
HFD1_k127_7918973_5 - - - - 0.00000000000000000000000000000000000000000000000000000002597 208.0
HFD1_k127_7918973_6 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000002177 205.0
HFD1_k127_7918973_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000006935 173.0
HFD1_k127_7918973_8 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000005952 127.0
HFD1_k127_7918973_9 alpha beta - - - 0.00000000000000006898 97.0
HFD1_k127_7924399_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000309 260.0
HFD1_k127_798332_0 - - - - 0.000000000000000000000000000000000000000000000000000119 191.0
HFD1_k127_798332_1 SpoIIAA-like - - - 0.000000000000000000000000000000000000000001843 161.0
HFD1_k127_798332_2 Protein of unknown function (DUF2905) - - - 0.00000000000000001277 84.0
HFD1_k127_798332_3 SCP-2 sterol transfer family - - - 0.0000000111 55.0
HFD1_k127_7987541_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002686 249.0
HFD1_k127_7987541_1 Cold shock protein K03704 - - 0.0000000000000000000000002814 107.0
HFD1_k127_7987541_2 - - - - 0.00000000000000000000005033 106.0
HFD1_k127_7987541_3 Protein conserved in bacteria - - - 0.00000107 60.0
HFD1_k127_804441_0 Caspase domain - - - 0.000000000000000000008049 105.0
HFD1_k127_811719_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1090.0
HFD1_k127_811719_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 2.561e-222 719.0
HFD1_k127_811719_10 COGs COG1432 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000268 217.0
HFD1_k127_811719_11 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000009971 182.0
HFD1_k127_811719_12 electron transfer activity - - - 0.00000000000000000000000000000000000000003486 169.0
HFD1_k127_811719_13 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000001349 158.0
HFD1_k127_811719_14 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.000000000000000000000000000000000008741 141.0
HFD1_k127_811719_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000003145 141.0
HFD1_k127_811719_16 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.00000000000000000000000000001574 137.0
HFD1_k127_811719_17 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000008377 110.0
HFD1_k127_811719_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 583.0
HFD1_k127_811719_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 481.0
HFD1_k127_811719_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 392.0
HFD1_k127_811719_5 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 385.0
HFD1_k127_811719_6 RNA polymerase sigma-54 factor K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 377.0
HFD1_k127_811719_7 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 316.0
HFD1_k127_811719_8 histidine kinase, HAMP K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 302.0
HFD1_k127_811719_9 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000964 285.0
HFD1_k127_818448_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 361.0
HFD1_k127_818448_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000003322 234.0
HFD1_k127_818448_2 WD40 repeats - - - 0.000000000000000000001192 95.0
HFD1_k127_822013_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1281.0
HFD1_k127_822013_1 Peptidase dimerisation domain - - - 8.914e-215 677.0
HFD1_k127_822013_10 methyltransferase activity - - - 0.0000000000000000000000000000002467 130.0
HFD1_k127_822013_11 spectrin binding - - - 0.000000000000000000000000001389 122.0
HFD1_k127_822013_13 Forkhead associated domain - - - 0.0000000000000005389 90.0
HFD1_k127_822013_14 Cytochrome c K00406,K08906 - - 0.0000000001271 67.0
HFD1_k127_822013_15 Zinc finger domain - - - 0.00000746 58.0
HFD1_k127_822013_2 Protein of unknown function (DUF763) K09003 - - 7.225e-194 611.0
HFD1_k127_822013_3 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 572.0
HFD1_k127_822013_4 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 516.0
HFD1_k127_822013_5 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 458.0
HFD1_k127_822013_6 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 365.0
HFD1_k127_822013_7 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000003037 224.0
HFD1_k127_822013_8 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.000000000000000000000000000000000000000000000000005737 190.0
HFD1_k127_822013_9 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000000000000002613 168.0
HFD1_k127_825940_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 432.0
HFD1_k127_825940_2 COG2931 RTX toxins and related Ca2 -binding - - - 0.0000000006915 65.0
HFD1_k127_825940_3 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000007448 53.0
HFD1_k127_825940_4 - - - - 0.0004774 53.0
HFD1_k127_827536_0 transport - - - 4.012e-257 816.0
HFD1_k127_827536_1 - - - - 0.000000000000000000293 92.0
HFD1_k127_827536_2 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia - - - 0.00000000008665 66.0
HFD1_k127_827536_3 Belongs to the 'phage' integrase family - - - 0.0000000005974 62.0
HFD1_k127_827536_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000696 59.0
HFD1_k127_827536_5 Belongs to the UPF0225 family K09858 - - 0.000003214 49.0
HFD1_k127_832157_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 629.0
HFD1_k127_832157_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 458.0
HFD1_k127_832157_10 Sulfatase-modifying factor enzyme 1 K20333 - - 0.00000000000000000000000000000000000000002281 175.0
HFD1_k127_832157_11 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000006287 160.0
HFD1_k127_832157_12 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000001236 143.0
HFD1_k127_832157_13 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000001411 131.0
HFD1_k127_832157_14 - - - - 0.000000001371 68.0
HFD1_k127_832157_15 EF-hand domain pair - - - 0.000000005429 66.0
HFD1_k127_832157_16 Sh3 type 3 domain protein - - - 0.00000002111 65.0
HFD1_k127_832157_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 380.0
HFD1_k127_832157_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 323.0
HFD1_k127_832157_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 300.0
HFD1_k127_832157_5 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005082 270.0
HFD1_k127_832157_6 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000002804 218.0
HFD1_k127_832157_7 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000249 192.0
HFD1_k127_832157_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000001201 182.0
HFD1_k127_832157_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000008289 181.0
HFD1_k127_837556_0 carboxylic acid catabolic process K01187 - 3.2.1.20 2.015e-275 860.0
HFD1_k127_837556_1 histidine kinase A domain protein - - - 1.354e-221 724.0
HFD1_k127_837556_10 OmpA family K02557,K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 487.0
HFD1_k127_837556_11 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 467.0
HFD1_k127_837556_12 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 461.0
HFD1_k127_837556_13 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 447.0
HFD1_k127_837556_14 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 435.0
HFD1_k127_837556_15 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133,K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363 1.2.1.11,1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 423.0
HFD1_k127_837556_16 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 414.0
HFD1_k127_837556_17 Methane oxygenase PmoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 411.0
HFD1_k127_837556_18 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 403.0
HFD1_k127_837556_19 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 413.0
HFD1_k127_837556_2 TonB-dependent receptor - - - 8.896e-209 688.0
HFD1_k127_837556_20 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 382.0
HFD1_k127_837556_21 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 372.0
HFD1_k127_837556_22 COG2721 Altronate dehydratase K01685 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 382.0
HFD1_k127_837556_23 Arylsulfatase a K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 376.0
HFD1_k127_837556_24 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 366.0
HFD1_k127_837556_25 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 341.0
HFD1_k127_837556_26 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 338.0
HFD1_k127_837556_27 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 324.0
HFD1_k127_837556_28 oxidation-reduction process K00826 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006694,GO:0006703,GO:0006706,GO:0008150,GO:0008152,GO:0008202,GO:0008210,GO:0008610,GO:0009056,GO:0009058,GO:0009987,GO:0010817,GO:0016042,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0033764,GO:0034754,GO:0042445,GO:0042446,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0047045,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 320.0
HFD1_k127_837556_29 peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 318.0
HFD1_k127_837556_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.585e-206 672.0
HFD1_k127_837556_30 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 309.0
HFD1_k127_837556_31 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 317.0
HFD1_k127_837556_32 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 319.0
HFD1_k127_837556_33 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
HFD1_k127_837556_34 macromolecule localization K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 293.0
HFD1_k127_837556_35 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 291.0
HFD1_k127_837556_36 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001209 287.0
HFD1_k127_837556_37 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001249 276.0
HFD1_k127_837556_38 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003359 273.0
HFD1_k127_837556_39 myo-inosose-2 dehydratase activity K03335,K15652 - 4.2.1.118,4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000004456 272.0
HFD1_k127_837556_4 Glycosyltransferase like family 2 - - - 8.968e-205 651.0
HFD1_k127_837556_40 G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005542 265.0
HFD1_k127_837556_41 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008379 260.0
HFD1_k127_837556_42 Predicted integral membrane protein (DUF2270) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002407 255.0
HFD1_k127_837556_43 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002663 255.0
HFD1_k127_837556_44 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000008671 244.0
HFD1_k127_837556_45 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000002695 244.0
HFD1_k127_837556_46 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000008015 238.0
HFD1_k127_837556_47 TIGRFAM Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000006331 223.0
HFD1_k127_837556_48 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000001663 228.0
HFD1_k127_837556_49 Putative peptidoglycan binding domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000008325 214.0
HFD1_k127_837556_5 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 612.0
HFD1_k127_837556_50 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000001984 200.0
HFD1_k127_837556_51 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000007101 201.0
HFD1_k127_837556_52 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000009375 202.0
HFD1_k127_837556_53 Protein conserved in bacteria K07011 - - 0.0000000000000000000000000000000000000000000000000000003078 199.0
HFD1_k127_837556_54 photosynthesis - - - 0.00000000000000000000000000000000000000000000000000001263 195.0
HFD1_k127_837556_55 - - - - 0.0000000000000000000000000000000000000000000000001022 186.0
HFD1_k127_837556_56 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000003437 189.0
HFD1_k127_837556_57 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000272 188.0
HFD1_k127_837556_58 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000005428 184.0
HFD1_k127_837556_59 protein methyltransferase activity K02687 - - 0.0000000000000000000000000000000000000000000002833 186.0
HFD1_k127_837556_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 584.0
HFD1_k127_837556_60 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000006126 177.0
HFD1_k127_837556_61 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000000008235 161.0
HFD1_k127_837556_62 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000001345 168.0
HFD1_k127_837556_63 ig-like, plexins, transcription factors - - - 0.000000000000000000000000000000000000000001075 181.0
HFD1_k127_837556_64 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000002196 170.0
HFD1_k127_837556_65 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000001641 156.0
HFD1_k127_837556_66 - - - - 0.0000000000000000000000002482 108.0
HFD1_k127_837556_68 transglycosylase associated protein - - - 0.0000000000000000002669 90.0
HFD1_k127_837556_69 heme-binding sites - - - 0.000000000000002262 91.0
HFD1_k127_837556_7 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 544.0
HFD1_k127_837556_70 Putative transmembrane protein (PGPGW) - - - 0.000000000000005292 79.0
HFD1_k127_837556_71 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.000000000007041 77.0
HFD1_k127_837556_72 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.0000000004345 74.0
HFD1_k127_837556_73 Periplasmic or secreted lipoprotein - - - 0.000003478 59.0
HFD1_k127_837556_75 endonuclease exonuclease phosphatase - - - 0.0004436 53.0
HFD1_k127_837556_8 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 529.0
HFD1_k127_837556_9 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 495.0
HFD1_k127_838185_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 493.0
HFD1_k127_838185_1 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 410.0
HFD1_k127_838185_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000001044 89.0
HFD1_k127_838185_3 Protein of unknown function (DUF3616) - - - 0.000000000000008094 88.0
HFD1_k127_838185_4 Carbonic anhydrase K01673 - 4.2.1.1 0.00002606 52.0
HFD1_k127_838185_5 Serine dehydratase K01752 - 4.3.1.17 0.0001341 45.0
HFD1_k127_843099_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1273.0
HFD1_k127_843099_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 618.0
HFD1_k127_843099_10 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 380.0
HFD1_k127_843099_11 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 390.0
HFD1_k127_843099_12 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 349.0
HFD1_k127_843099_13 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 327.0
HFD1_k127_843099_14 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 321.0
HFD1_k127_843099_15 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 309.0
HFD1_k127_843099_16 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 305.0
HFD1_k127_843099_17 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 301.0
HFD1_k127_843099_18 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
HFD1_k127_843099_19 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001802 280.0
HFD1_k127_843099_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 544.0
HFD1_k127_843099_20 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001237 274.0
HFD1_k127_843099_21 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000484 299.0
HFD1_k127_843099_22 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 270.0
HFD1_k127_843099_23 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000001264 233.0
HFD1_k127_843099_24 Mechanosensitive ion channel K05802,K22051 - - 0.00000000000000000000000000000000000000000000000000000000000002293 225.0
HFD1_k127_843099_25 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000000000000000000003026 200.0
HFD1_k127_843099_26 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000146 198.0
HFD1_k127_843099_27 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.0000000000000000000000000000000000000000000000007094 192.0
HFD1_k127_843099_28 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000002141 192.0
HFD1_k127_843099_29 - - - - 0.00000000000000000000000000000000000000000002343 167.0
HFD1_k127_843099_3 succinyl-diaminopimelate desuccinylase activity K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 484.0
HFD1_k127_843099_30 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000702 155.0
HFD1_k127_843099_31 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000006849 146.0
HFD1_k127_843099_32 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000000281 133.0
HFD1_k127_843099_33 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000001087 132.0
HFD1_k127_843099_34 - - - - 0.00000000000000000000000000004849 121.0
HFD1_k127_843099_35 Uncharacterized protein conserved in bacteria (DUF2199) - - - 0.0000000000000000000000001747 112.0
HFD1_k127_843099_36 Regulatory protein, FmdB family - - - 0.0000000000000000000006028 96.0
HFD1_k127_843099_37 DNA-binding transcription factor activity K15973 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000003298 99.0
HFD1_k127_843099_38 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000000000001395 95.0
HFD1_k127_843099_39 Putative regulatory protein - - - 0.00000000000000000005144 93.0
HFD1_k127_843099_4 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 445.0
HFD1_k127_843099_40 - - - - 0.0000000000000000002932 94.0
HFD1_k127_843099_41 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000001179 88.0
HFD1_k127_843099_42 Tetratricopeptide repeats - - - 0.0000000000000007089 91.0
HFD1_k127_843099_43 membrane - - - 0.000000000000001036 93.0
HFD1_k127_843099_44 Tetratricopeptide repeat - - - 0.000000000002492 79.0
HFD1_k127_843099_5 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 437.0
HFD1_k127_843099_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 444.0
HFD1_k127_843099_7 2-amino-3-ketobutyrate coenzyme A ligase K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 392.0
HFD1_k127_843099_8 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 404.0
HFD1_k127_843099_9 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 386.0
HFD1_k127_848279_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 531.0
HFD1_k127_848279_1 CDP-archaeol synthase - - - 0.0000000000000000005269 93.0
HFD1_k127_84903_0 Carboxypeptidase regulatory-like domain - - - 8.348e-307 979.0
HFD1_k127_84903_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.54e-266 842.0
HFD1_k127_84903_10 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 464.0
HFD1_k127_84903_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 460.0
HFD1_k127_84903_12 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 426.0
HFD1_k127_84903_13 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 391.0
HFD1_k127_84903_14 nuclease activity - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 377.0
HFD1_k127_84903_15 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 378.0
HFD1_k127_84903_16 Transporter-associated region K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 363.0
HFD1_k127_84903_17 PFAM Basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HFD1_k127_84903_18 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 371.0
HFD1_k127_84903_19 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 344.0
HFD1_k127_84903_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.798e-218 683.0
HFD1_k127_84903_20 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 310.0
HFD1_k127_84903_21 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 304.0
HFD1_k127_84903_22 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000191 292.0
HFD1_k127_84903_23 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002455 287.0
HFD1_k127_84903_24 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000214 248.0
HFD1_k127_84903_25 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000002792 259.0
HFD1_k127_84903_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000007222 247.0
HFD1_k127_84903_27 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000005376 247.0
HFD1_k127_84903_28 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000007047 249.0
HFD1_k127_84903_29 abc transporter, permease K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000004374 233.0
HFD1_k127_84903_3 PFAM AMP-dependent synthetase and ligase K00666 - - 1.791e-214 679.0
HFD1_k127_84903_30 ABC-type molybdate transport system, ATPase component K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000007344 240.0
HFD1_k127_84903_31 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000001041 222.0
HFD1_k127_84903_32 PFAM Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000005404 221.0
HFD1_k127_84903_33 - - - - 0.000000000000000000000000000000000000000000000000000000001336 215.0
HFD1_k127_84903_34 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000001312 202.0
HFD1_k127_84903_35 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000000000001674 205.0
HFD1_k127_84903_36 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000008775 196.0
HFD1_k127_84903_37 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000002185 197.0
HFD1_k127_84903_38 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000005373 193.0
HFD1_k127_84903_39 - - - - 0.000000000000000000000000000000000000000000000000006874 183.0
HFD1_k127_84903_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.325e-211 667.0
HFD1_k127_84903_40 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000007548 196.0
HFD1_k127_84903_41 - K07018 - - 0.0000000000000000000000000000000000000000000000001586 186.0
HFD1_k127_84903_42 Phage integrase, N-terminal SAM-like domain K14059 - - 0.000000000000000000000000000000000000000000000001164 188.0
HFD1_k127_84903_43 DinB superfamily - - - 0.000000000000000000000000000000000000000000004871 168.0
HFD1_k127_84903_44 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000004015 144.0
HFD1_k127_84903_45 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000001658 143.0
HFD1_k127_84903_46 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000018 143.0
HFD1_k127_84903_47 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000001423 131.0
HFD1_k127_84903_48 von Willebrand factor, type A - - - 0.0000000000000000000000000005491 130.0
HFD1_k127_84903_49 5'-nucleotidase - - - 0.000000000000000000000008507 115.0
HFD1_k127_84903_5 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.1e-204 644.0
HFD1_k127_84903_50 Tyrosine phosphatase family - - - 0.000000000000000000004126 101.0
HFD1_k127_84903_51 oxidoreductase activity K12511 - - 0.000000000000000003729 96.0
HFD1_k127_84903_52 LysM domain K01185,K02030,K04043 - 3.2.1.17 0.000000000000000004023 96.0
HFD1_k127_84903_53 sequence-specific DNA binding K03719 - - 0.00000000000000009077 83.0
HFD1_k127_84903_54 iron ion homeostasis - - - 0.0000000000000004541 91.0
HFD1_k127_84903_55 YacP-like NYN domain - - - 0.00000000000009228 78.0
HFD1_k127_84903_56 Endonuclease I - - - 0.000000006296 68.0
HFD1_k127_84903_57 TPR repeat - - - 0.00000006083 65.0
HFD1_k127_84903_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 547.0
HFD1_k127_84903_60 Helix-turn-helix domain - - - 0.0007132 48.0
HFD1_k127_84903_7 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 535.0
HFD1_k127_84903_8 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 472.0
HFD1_k127_84903_9 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 467.0
HFD1_k127_850422_0 Transcriptional regulator - - - 0.0000002026 59.0
HFD1_k127_852550_0 Insulinase (Peptidase family M16) K07263 - - 3.699e-255 819.0
HFD1_k127_852550_1 Prokaryotic cytochrome b561 - - - 2.743e-232 736.0
HFD1_k127_852550_10 oxidoreductase activity K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000101 299.0
HFD1_k127_852550_11 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004762 258.0
HFD1_k127_852550_12 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000002097 224.0
HFD1_k127_852550_13 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000002384 232.0
HFD1_k127_852550_14 Cytochrome b(N-terminal)/b6/petB K00412,K02635,K02637,K03887,K03891,K15879 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009512,GO:0009579,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044436,GO:0044459,GO:0044464,GO:0070069,GO:0071944 - 0.0000000000000000000000000000000000000000000000000002117 199.0
HFD1_k127_852550_15 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000003762 180.0
HFD1_k127_852550_16 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000001987 135.0
HFD1_k127_852550_17 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000000000005592 101.0
HFD1_k127_852550_18 YwiC-like protein - - - 0.000000000000000003903 94.0
HFD1_k127_852550_19 Domain of unknown function (DU1801) - - - 0.00000000000000003665 87.0
HFD1_k127_852550_2 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 479.0
HFD1_k127_852550_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000003914 83.0
HFD1_k127_852550_21 Universal stress protein - - - 0.000000000000001565 82.0
HFD1_k127_852550_22 - - - - 0.00000000004771 70.0
HFD1_k127_852550_23 heat shock protein binding - - - 0.00007341 54.0
HFD1_k127_852550_24 Cytochrome c553 K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0001007 50.0
HFD1_k127_852550_26 Belongs to the GSP D family - - - 0.0006581 50.0
HFD1_k127_852550_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 479.0
HFD1_k127_852550_4 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 404.0
HFD1_k127_852550_5 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 403.0
HFD1_k127_852550_6 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 382.0
HFD1_k127_852550_7 denitrification pathway K02569,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 398.0
HFD1_k127_852550_8 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 376.0
HFD1_k127_852550_9 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 346.0
HFD1_k127_860287_0 Mate efflux family protein K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 536.0
HFD1_k127_860287_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 367.0
HFD1_k127_860287_2 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005501 274.0
HFD1_k127_860287_3 MASE1 - - - 0.000000000000000000000000000000000000000000002005 185.0
HFD1_k127_861846_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.471e-207 662.0
HFD1_k127_861846_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 430.0
HFD1_k127_861846_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 335.0
HFD1_k127_861846_3 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000000000000000000000000000000000000002931 233.0
HFD1_k127_861846_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000009513 201.0
HFD1_k127_861846_5 Redoxin - - - 0.000000000000000000000000000000002923 146.0
HFD1_k127_861846_6 domain protein K14194 - - 0.00000000000000002765 96.0
HFD1_k127_861846_7 domain protein K14194 - - 0.00000000001164 78.0
HFD1_k127_861846_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.0000001851 61.0
HFD1_k127_86274_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 363.0
HFD1_k127_86649_0 Ankyrin repeats (many copies) K06015,K06867,K06886 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000007933 209.0
HFD1_k127_872628_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 502.0
HFD1_k127_872628_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000799 127.0
HFD1_k127_872628_2 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000003578 113.0
HFD1_k127_872628_3 Tetratricopeptide repeat - - - 0.000000000000000000008399 106.0
HFD1_k127_872628_5 Outer membrane lipoprotein - - - 0.00000001936 66.0
HFD1_k127_872628_6 Secretion system protein K12511 - - 0.00009728 45.0
HFD1_k127_875778_0 Prolyl oligopeptidase family - - - 7.56e-232 736.0
HFD1_k127_875778_1 Major Facilitator Superfamily - - - 2.661e-204 649.0
HFD1_k127_875778_2 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 543.0
HFD1_k127_875778_3 Belongs to the Pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 362.0
HFD1_k127_875778_4 NADPH:quinone reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 353.0
HFD1_k127_875778_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 295.0
HFD1_k127_875778_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000007672 194.0
HFD1_k127_875778_7 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.0000000000000000000000000000000000000000004363 158.0
HFD1_k127_875778_8 Thioesterase-like superfamily - - - 0.00000000000000000000000000000001613 131.0
HFD1_k127_875778_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.000000000000000000000000001262 119.0
HFD1_k127_883762_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1793.0
HFD1_k127_883762_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1096.0
HFD1_k127_883762_10 Voltage-dependent anion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 545.0
HFD1_k127_883762_11 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 551.0
HFD1_k127_883762_12 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 528.0
HFD1_k127_883762_13 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 502.0
HFD1_k127_883762_14 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 476.0
HFD1_k127_883762_15 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 463.0
HFD1_k127_883762_16 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 430.0
HFD1_k127_883762_17 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 402.0
HFD1_k127_883762_18 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 383.0
HFD1_k127_883762_19 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 381.0
HFD1_k127_883762_2 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 9.47e-304 940.0
HFD1_k127_883762_20 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 375.0
HFD1_k127_883762_21 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 370.0
HFD1_k127_883762_22 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 377.0
HFD1_k127_883762_23 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 359.0
HFD1_k127_883762_24 phosphohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 341.0
HFD1_k127_883762_25 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 340.0
HFD1_k127_883762_26 TIGRFAM parallel beta-helix repeat (two copies) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 329.0
HFD1_k127_883762_27 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 320.0
HFD1_k127_883762_28 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 317.0
HFD1_k127_883762_29 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 305.0
HFD1_k127_883762_3 4Fe-4S dicluster domain K00184 - - 1.699e-274 875.0
HFD1_k127_883762_30 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 311.0
HFD1_k127_883762_31 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 294.0
HFD1_k127_883762_32 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000072 310.0
HFD1_k127_883762_33 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003867 306.0
HFD1_k127_883762_34 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005315 265.0
HFD1_k127_883762_35 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003108 258.0
HFD1_k127_883762_36 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004985 252.0
HFD1_k127_883762_37 Domain of Unknown function (DUF542) K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000007032 242.0
HFD1_k127_883762_38 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000905 237.0
HFD1_k127_883762_39 - - - - 0.000000000000000000000000000000000000000000000000000000000000002779 229.0
HFD1_k127_883762_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 7.299e-244 769.0
HFD1_k127_883762_40 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000392 221.0
HFD1_k127_883762_41 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.000000000000000000000000000000000000000000000000000000000002199 215.0
HFD1_k127_883762_42 - - - - 0.00000000000000000000000000000000000000000000000000000000003003 221.0
HFD1_k127_883762_43 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000000000886 213.0
HFD1_k127_883762_44 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000754 202.0
HFD1_k127_883762_45 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000002207 205.0
HFD1_k127_883762_46 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000007298 218.0
HFD1_k127_883762_47 - - - - 0.000000000000000000000000000000000000000000000000000002014 207.0
HFD1_k127_883762_48 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000003507 197.0
HFD1_k127_883762_49 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000829 195.0
HFD1_k127_883762_5 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 1.109e-232 729.0
HFD1_k127_883762_50 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000002144 191.0
HFD1_k127_883762_51 ABC-2 family transporter protein K01992,K19341 - - 0.0000000000000000000000000000000000000000000000001771 186.0
HFD1_k127_883762_52 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000005836 199.0
HFD1_k127_883762_53 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000001068 181.0
HFD1_k127_883762_54 Cytochrome c - - - 0.000000000000000000000000000000000000000000002275 175.0
HFD1_k127_883762_55 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000478 166.0
HFD1_k127_883762_56 cytochrome c - - - 0.000000000000000000000000000000000000000005219 160.0
HFD1_k127_883762_57 Capsular polysaccharide biosynthesis protein CapK - - - 0.000000000000000000000000000000000000000009557 171.0
HFD1_k127_883762_58 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.00000000000000000000000000000000000000001741 158.0
HFD1_k127_883762_59 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000001834 140.0
HFD1_k127_883762_6 Polysulphide reductase, NrfD K00185 - - 1.458e-214 675.0
HFD1_k127_883762_60 Hemerythrin hhe cation binding - - - 0.000000000000000000000000000000001849 139.0
HFD1_k127_883762_61 cheY-homologous receiver domain - - - 0.00000000000000000000000000000002948 131.0
HFD1_k127_883762_62 - - - - 0.0000000000000000000000000000009216 131.0
HFD1_k127_883762_63 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000001097 121.0
HFD1_k127_883762_64 Protein of unknown function (DUF1440) K08996 - - 0.0000000000000000000000000001372 123.0
HFD1_k127_883762_65 Di-glucose binding within endoplasmic reticulum - - - 0.0000000000000000000000000002499 134.0
HFD1_k127_883762_66 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000006184 127.0
HFD1_k127_883762_67 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.0000000000000000000000000006561 117.0
HFD1_k127_883762_68 Plasmid stabilization - - - 0.0000000000000000000000000009688 113.0
HFD1_k127_883762_69 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000002268 130.0
HFD1_k127_883762_7 DNA polymerase beta thumb K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 582.0
HFD1_k127_883762_70 biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000000006587 121.0
HFD1_k127_883762_72 NosL K19342 - - 0.00000000000000000000003403 105.0
HFD1_k127_883762_73 - - - - 0.00000000000000000003638 92.0
HFD1_k127_883762_74 TIGRFAM Transcriptional regulator, Rrf2 - - - 0.00000000000000000004888 95.0
HFD1_k127_883762_75 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000001413 96.0
HFD1_k127_883762_76 - K05594 - - 0.000000000000000002437 90.0
HFD1_k127_883762_77 - - - - 0.00000000000000002211 86.0
HFD1_k127_883762_78 O-Antigen ligase - - - 0.0000000000000002975 92.0
HFD1_k127_883762_79 - - - - 0.0000000000000003139 85.0
HFD1_k127_883762_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 560.0
HFD1_k127_883762_80 Chain-length determining protein - - - 0.000000000000001711 90.0
HFD1_k127_883762_81 Hemerythrin HHE cation binding domain - - - 0.000000000000006472 81.0
HFD1_k127_883762_82 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000003962 78.0
HFD1_k127_883762_83 - - - - 0.000000000003843 70.0
HFD1_k127_883762_84 Periplasmic protein involved in polysaccharide export K01991 - - 0.00000000004876 73.0
HFD1_k127_883762_85 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000005633 67.0
HFD1_k127_883762_86 helix_turn_helix, Lux Regulon K07684 - - 0.00000007464 63.0
HFD1_k127_883762_87 Belongs to the TPP enzyme family K00156 - 1.2.5.1 0.0000003772 53.0
HFD1_k127_883762_9 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 566.0
HFD1_k127_892215_0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family K01406,K13276,K20276 - 3.4.24.40 0.0000001654 63.0
HFD1_k127_895996_0 MacB-like periplasmic core domain - - - 7.524e-218 702.0
HFD1_k127_895996_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 524.0
HFD1_k127_895996_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 303.0
HFD1_k127_895996_3 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004321 242.0
HFD1_k127_895996_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001633 206.0
HFD1_k127_895996_5 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000004759 181.0
HFD1_k127_895996_6 efflux transmembrane transporter activity - - - 0.0000000000000000000000000004827 123.0
HFD1_k127_895996_7 - - - - 0.000000000000008132 77.0
HFD1_k127_895996_8 - - - - 0.000000006327 59.0
HFD1_k127_896128_0 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000006241 202.0
HFD1_k127_89957_0 efflux transmembrane transporter activity - - - 4.778e-203 661.0
HFD1_k127_89957_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 565.0
HFD1_k127_89957_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 473.0
HFD1_k127_91027_0 cellulose binding - - - 0.0 1069.0
HFD1_k127_91027_1 Domain of unknown function (DUF3471) - - - 2.505e-195 619.0
HFD1_k127_91027_2 PFAM WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003044 277.0
HFD1_k127_91027_3 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004027 259.0
HFD1_k127_91027_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000001012 99.0
HFD1_k127_91027_6 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000001105 78.0
HFD1_k127_933410_0 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000008513 188.0
HFD1_k127_933410_1 Glucuronate isomerase K01812 - 5.3.1.12 0.00000000000000000000000000000000000000000012 160.0
HFD1_k127_933410_2 YCII-related domain - - - 0.00005706 49.0
HFD1_k127_940822_0 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.0000000000000000000172 99.0
HFD1_k127_940822_1 DNA methylase - - - 0.0000000000000002058 92.0
HFD1_k127_940822_2 ParB-like nuclease domain K03497 - - 0.00000000002315 76.0
HFD1_k127_940822_3 AAA domain - - - 0.000003778 58.0
HFD1_k127_940822_5 - - - - 0.0001548 46.0
HFD1_k127_94227_0 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 399.0
HFD1_k127_94227_1 transposase activity - - - 0.0000000000000000000000002449 105.0
HFD1_k127_94373_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 5.771e-307 960.0
HFD1_k127_94373_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.389e-276 857.0
HFD1_k127_94373_10 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000000000001899 108.0
HFD1_k127_94373_11 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000005466 99.0
HFD1_k127_94373_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000001045 81.0
HFD1_k127_94373_13 - - - - 0.00000000007473 69.0
HFD1_k127_94373_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 437.0
HFD1_k127_94373_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 432.0
HFD1_k127_94373_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 397.0
HFD1_k127_94373_5 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 306.0
HFD1_k127_94373_6 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000002164 250.0
HFD1_k127_94373_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001415 235.0
HFD1_k127_94373_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000001177 187.0
HFD1_k127_94373_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000003185 180.0
HFD1_k127_953927_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000002433 139.0
HFD1_k127_953927_1 Endonuclease-reverse transcriptase K11320 - - 0.000000000000004019 79.0
HFD1_k127_957247_0 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 360.0
HFD1_k127_957247_1 PFAM transposase IS3 IS911 family protein - - - 0.0002103 45.0
HFD1_k127_973875_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.399e-260 828.0
HFD1_k127_989695_0 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000331 212.0
HFD1_k127_989695_1 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000001736 162.0
HFD1_k127_989695_2 - - - - 0.0007745 42.0
HFD1_k127_997046_0 Tricorn protease PDZ domain K08676 - - 0.0 1332.0
HFD1_k127_997046_1 domain protein - - - 9.806e-243 794.0
HFD1_k127_997046_10 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 543.0
HFD1_k127_997046_11 Domain of unknown function (DUF3471) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 528.0
HFD1_k127_997046_12 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 534.0
HFD1_k127_997046_13 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 489.0
HFD1_k127_997046_14 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000006211 246.0
HFD1_k127_997046_15 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000008943 247.0
HFD1_k127_997046_16 Probable molybdopterin binding domain K03638,K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000008803 176.0
HFD1_k127_997046_17 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000000003942 166.0
HFD1_k127_997046_18 - - - - 0.0000000000000000000000000006536 131.0
HFD1_k127_997046_19 WD40-like Beta Propeller Repeat - - - 0.00000000004284 65.0
HFD1_k127_997046_2 efflux transmembrane transporter activity K02004 - - 1.86e-235 756.0
HFD1_k127_997046_3 efflux transmembrane transporter activity K02004 - - 6.53e-222 714.0
HFD1_k127_997046_4 Involved in the tonB-independent uptake of proteins - - - 1.761e-212 690.0
HFD1_k127_997046_5 efflux transmembrane transporter activity - - - 1.915e-197 642.0
HFD1_k127_997046_6 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 599.0
HFD1_k127_997046_7 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 591.0
HFD1_k127_997046_8 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 585.0
HFD1_k127_997046_9 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 556.0
HFD1_k127_997447_0 cell adhesion involved in biofilm formation K13735,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 451.0
HFD1_k127_997447_1 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 317.0
HFD1_k127_997447_2 von Willebrand factor, type A K07114 - - 0.0000000000000000000003952 111.0
HFD1_k127_997447_3 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000003534 111.0
HFD1_k127_997447_4 amine dehydrogenase activity - - - 0.0000000001142 76.0