Overview

ID MAG01612
Name HFD1_bin.19
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family GWC2-71-9
Genus DASTHG01
Species
Assembly information
Completeness (%) 60.51
Contamination (%) 1.6
GC content (%) 70.0
N50 (bp) 2,858
Genome size (bp) 3,184,778

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3448

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1001177_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000003088 224.0
HFD1_k127_1001177_1 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000000000000000000000000000000000000000001143 192.0
HFD1_k127_1001177_2 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000002622 60.0
HFD1_k127_1004263_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01531,K01535 - 3.6.3.2,3.6.3.6 2.06e-311 991.0
HFD1_k127_1004263_1 Putative peptidoglycan binding domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 325.0
HFD1_k127_1004499_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 358.0
HFD1_k127_1004499_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000001444 143.0
HFD1_k127_1004499_2 NUDIX domain - - - 0.000000000000000000000000001725 114.0
HFD1_k127_1009875_0 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000007873 195.0
HFD1_k127_101077_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000001013 218.0
HFD1_k127_101077_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000005922 59.0
HFD1_k127_1014062_0 siderophore transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 398.0
HFD1_k127_1016248_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 7.845e-242 754.0
HFD1_k127_1016248_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 308.0
HFD1_k127_1016248_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000554 270.0
HFD1_k127_1016248_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000004779 148.0
HFD1_k127_1016248_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000001835 80.0
HFD1_k127_1016248_5 PFAM peptidase M16 domain protein - - - 0.000000000001398 71.0
HFD1_k127_101743_0 Transposase - - - 3.912e-225 709.0
HFD1_k127_101743_1 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 419.0
HFD1_k127_1026586_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 378.0
HFD1_k127_1026586_1 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000000000001554 197.0
HFD1_k127_1026586_2 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000001244 176.0
HFD1_k127_1026586_3 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000000000000000000000001274 134.0
HFD1_k127_1026586_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0001353 49.0
HFD1_k127_1028939_0 aminopeptidase N - - - 3.403e-282 886.0
HFD1_k127_1028939_1 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 505.0
HFD1_k127_1028939_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000001567 179.0
HFD1_k127_1028939_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000131 117.0
HFD1_k127_1028939_4 lactoylglutathione lyase activity - - - 0.000000000000000000005851 104.0
HFD1_k127_1028939_5 Pathogenicity locus - - - 0.000000000000000004175 93.0
HFD1_k127_1028939_6 Protein of unknown function (DUF2914) - - - 0.0000000000000001687 88.0
HFD1_k127_1030372_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000009513 131.0
HFD1_k127_1034452_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 329.0
HFD1_k127_1034452_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 303.0
HFD1_k127_1034452_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008062 256.0
HFD1_k127_1034452_3 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000008828 231.0
HFD1_k127_1034452_4 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000001744 201.0
HFD1_k127_1037140_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 332.0
HFD1_k127_1055523_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 335.0
HFD1_k127_1055523_1 - - - - 0.000000000004147 73.0
HFD1_k127_1055523_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0001648 50.0
HFD1_k127_1057373_0 PFAM Transposase, Mutator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 583.0
HFD1_k127_1057856_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000001228 252.0
HFD1_k127_1057856_1 PFAM Integrase catalytic region - - - 0.000000000972 70.0
HFD1_k127_1058090_0 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000005691 241.0
HFD1_k127_1058090_1 Thioredoxin-like - - - 0.0000000000000000000000000000000000006086 155.0
HFD1_k127_1064829_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 453.0
HFD1_k127_1064963_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 287.0
HFD1_k127_1064963_1 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000003198 228.0
HFD1_k127_1064963_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K04075,K15780 GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000009394 200.0
HFD1_k127_1071516_0 EDD domain protein, DegV family - - - 0.0000000000000000000000000000000000000001748 160.0
HFD1_k127_1071516_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000002563 130.0
HFD1_k127_1071516_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000004325 89.0
HFD1_k127_1084418_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000001511 241.0
HFD1_k127_1084418_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000005743 216.0
HFD1_k127_1084418_2 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.00000002263 65.0
HFD1_k127_1084418_3 Tetratricopeptide repeats - - - 0.0007996 51.0
HFD1_k127_108538_0 Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.483e-209 665.0
HFD1_k127_108538_1 Belongs to the 'phage' integrase family - - - 0.00000000000000226 78.0
HFD1_k127_1101871_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 386.0
HFD1_k127_1101871_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 0.0000000000000000000000000000000000000000000007938 175.0
HFD1_k127_1110466_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 470.0
HFD1_k127_1110466_1 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000005569 199.0
HFD1_k127_1110466_2 DDE_Tnp_1-associated - - - 0.0000000008418 59.0
HFD1_k127_1110466_3 DDE_Tnp_1-associated - - - 0.000000001028 62.0
HFD1_k127_1123977_0 CarboxypepD_reg-like domain - - - 1.771e-224 730.0
HFD1_k127_1123977_1 Carboxypeptidase regulatory-like domain K02014 - - 0.000000000000009979 83.0
HFD1_k127_112548_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009183 284.0
HFD1_k127_112548_1 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005539 278.0
HFD1_k127_1128352_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003177 284.0
HFD1_k127_1128352_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000003844 129.0
HFD1_k127_1128352_2 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000001329 118.0
HFD1_k127_1128352_3 Two component signalling adaptor domain K03408 - - 0.000000000001841 77.0
HFD1_k127_113876_0 Transposase IS66 family - - - 0.0000000000000000000000000000000000000001261 156.0
HFD1_k127_1150140_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 8.741e-235 743.0
HFD1_k127_1150140_1 conserved protein, contains double-stranded beta-helix domain K00450,K06720 - 1.13.11.4,4.2.1.108 0.00000003963 62.0
HFD1_k127_1153439_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.29e-280 879.0
HFD1_k127_1153439_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.067e-238 747.0
HFD1_k127_1153439_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 332.0
HFD1_k127_1153439_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000001004 221.0
HFD1_k127_1153439_4 Putative glucoamylase - - - 0.000000000000000000000009854 100.0
HFD1_k127_1157761_0 Transposase domain (DUF772) K07487 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 426.0
HFD1_k127_1157761_1 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000008264 230.0
HFD1_k127_1170190_0 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006338 274.0
HFD1_k127_1170190_1 PFAM Class III cytochrome C family - - - 0.0000000000000005669 83.0
HFD1_k127_1170190_2 YceI-like domain - - - 0.000002802 58.0
HFD1_k127_1170334_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1254.0
HFD1_k127_1170334_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 331.0
HFD1_k127_1170334_2 efflux transmembrane transporter activity - - - 0.000001164 51.0
HFD1_k127_1177342_0 heat shock protein binding - - - 0.000000000000000000000000000000000000003128 155.0
HFD1_k127_1177342_1 heat shock protein binding - - - 0.0000000000000000000000000000001741 129.0
HFD1_k127_1190564_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 466.0
HFD1_k127_1211128_0 DDE_Tnp_1-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
HFD1_k127_1215947_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000003001 139.0
HFD1_k127_1216945_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000008427 241.0
HFD1_k127_1216945_1 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000002627 219.0
HFD1_k127_1216945_2 chaperone-mediated protein folding - - - 0.00000000000000000001347 106.0
HFD1_k127_1216945_3 - - - - 0.0004026 45.0
HFD1_k127_1217210_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000763 228.0
HFD1_k127_1217210_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000006222 175.0
HFD1_k127_1221255_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001248 224.0
HFD1_k127_1221255_1 domain protein K20276 - - 0.0000000000000000000000000000000000002362 151.0
HFD1_k127_1223153_0 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 318.0
HFD1_k127_1223153_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000001518 235.0
HFD1_k127_123132_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004012 259.0
HFD1_k127_123132_1 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000005176 107.0
HFD1_k127_123132_2 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000007701 96.0
HFD1_k127_1243889_0 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 267.0
HFD1_k127_1243889_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000001005 239.0
HFD1_k127_1243889_2 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000002262 103.0
HFD1_k127_1244086_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 336.0
HFD1_k127_1252395_0 Isocitrate lyase K01637 - 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 594.0
HFD1_k127_1252395_1 protein secretion by the type I secretion system K11085 - - 0.00000000000000000000000000000000000000000000000000000000007309 206.0
HFD1_k127_1252395_2 Malate synthase K01638 - 2.3.3.9 0.0000003262 52.0
HFD1_k127_1255747_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 533.0
HFD1_k127_1255747_1 prohibitin homologues - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 400.0
HFD1_k127_1255747_2 Putative adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000004497 258.0
HFD1_k127_1255747_3 S23 ribosomal protein - - - 0.0000000000000000000000000000000003678 136.0
HFD1_k127_1255747_4 S4 RNA-binding domain K04762 - - 0.00000000000000000000000000000002096 132.0
HFD1_k127_1255747_5 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000003097 100.0
HFD1_k127_1255747_6 membrane - - - 0.00000000000000000000513 92.0
HFD1_k127_1255747_7 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000028 91.0
HFD1_k127_1261979_0 CarboxypepD_reg-like domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 399.0
HFD1_k127_126345_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009899 275.0
HFD1_k127_1268481_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 330.0
HFD1_k127_1268481_1 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 333.0
HFD1_k127_1268481_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K22110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004422 291.0
HFD1_k127_1268481_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000019 120.0
HFD1_k127_1268481_4 - - - - 0.00000000000009661 76.0
HFD1_k127_1276047_0 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000683 194.0
HFD1_k127_1276047_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000002964 95.0
HFD1_k127_1286193_0 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000004484 131.0
HFD1_k127_1286193_1 Peptidase family M1 domain - - - 0.00000000000000000002618 94.0
HFD1_k127_1288799_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000938 255.0
HFD1_k127_1288799_1 - - - - 0.00000000000000000000000007172 112.0
HFD1_k127_1288799_2 Peptidoglycan binding domain - - - 0.0000009415 57.0
HFD1_k127_129201_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 362.0
HFD1_k127_129201_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000004621 128.0
HFD1_k127_1295528_0 LysM domain K08307,K12204 - - 0.00000000000000000000000000005165 131.0
HFD1_k127_1295528_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.0000000000000000000003252 98.0
HFD1_k127_1331727_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 311.0
HFD1_k127_1331727_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003894 278.0
HFD1_k127_1331727_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000002062 147.0
HFD1_k127_1331727_3 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.0000000000000000000000000000000004839 150.0
HFD1_k127_1331727_4 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000001285 130.0
HFD1_k127_1331727_5 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 0.00000000000000000000000000009498 120.0
HFD1_k127_1335130_0 FAD dependent oxidoreductase - - - 9.42e-222 700.0
HFD1_k127_1335130_1 Histidine kinase-like ATPases K01768,K02488,K17763 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 358.0
HFD1_k127_1335130_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000005317 70.0
HFD1_k127_1354274_0 - - - - 0.00000000000000000000000000000000000004291 158.0
HFD1_k127_1354274_1 Sodium:solute symporter family K14393 - - 0.0000000001592 63.0
HFD1_k127_1354274_2 Membrane - - - 0.00000001611 64.0
HFD1_k127_1366387_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000008669 96.0
HFD1_k127_1366387_1 Transposase - - - 0.0001764 46.0
HFD1_k127_1369499_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000005278 233.0
HFD1_k127_13738_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 9.034e-207 660.0
HFD1_k127_13738_1 COGs COG1845 Heme copper-type cytochrome quinol oxidase subunit 3 K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000001191 233.0
HFD1_k127_13738_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000009077 176.0
HFD1_k127_13738_3 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000001405 104.0
HFD1_k127_13738_4 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000008575 88.0
HFD1_k127_1386616_0 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 366.0
HFD1_k127_1386616_1 Late embryogenesis abundant protein - - - 0.0000000000000000000000004505 113.0
HFD1_k127_138890_0 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 494.0
HFD1_k127_138890_1 acyl-CoA dehydrogenase - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000034 81.0
HFD1_k127_1391625_0 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 455.0
HFD1_k127_1391625_1 Polysaccharide deacetylase - - - 0.0000000000000000001976 95.0
HFD1_k127_1391625_2 geranylgeranyl reductase activity K10960,K17830 - 1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11 0.000006245 49.0
HFD1_k127_1395546_0 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000785 265.0
HFD1_k127_1395546_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000001301 50.0
HFD1_k127_1395546_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00002911 49.0
HFD1_k127_1398738_0 - - - - 0.000000000000000000000000000000000004976 145.0
HFD1_k127_1398738_1 transcriptional regulator - - - 0.000000000000000000003945 99.0
HFD1_k127_1403175_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 471.0
HFD1_k127_1403175_1 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001055 298.0
HFD1_k127_1403175_2 Sugar nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004798 270.0
HFD1_k127_1403175_3 Roadblock/LC7 domain K07131 - - 0.0000000000000000000000000005564 116.0
HFD1_k127_1403175_4 cheY-homologous receiver domain - - - 0.00000000000000006376 89.0
HFD1_k127_1403175_5 - - - - 0.000000000000002086 83.0
HFD1_k127_140722_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000003043 192.0
HFD1_k127_140722_1 - - - - 0.00000000000000000001647 104.0
HFD1_k127_1421950_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 501.0
HFD1_k127_1429224_0 protein domain associated with - - - 0.00000000000000000000000000000000000000000000000000002746 194.0
HFD1_k127_1429224_1 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567,K10778 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000000000000000001905 196.0
HFD1_k127_1429224_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000005145 136.0
HFD1_k127_1429224_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.000000000000000000000000000001802 123.0
HFD1_k127_1461991_0 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 542.0
HFD1_k127_1469070_0 Forkhead associated domain - - - 0.0000000000000000000000006588 116.0
HFD1_k127_14753_0 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 313.0
HFD1_k127_14753_1 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000002303 111.0
HFD1_k127_14753_2 serine-type peptidase activity K08676 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000002972 99.0
HFD1_k127_1483553_0 metal-dependent phosphohydrolase, HD sub domain K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002218 251.0
HFD1_k127_1483553_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000001044 98.0
HFD1_k127_1496619_0 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001439 283.0
HFD1_k127_1496619_1 Homeodomain-like domain - - - 0.0000000000000000000000167 102.0
HFD1_k127_1510090_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 402.0
HFD1_k127_1510090_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
HFD1_k127_1520418_0 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000000000000001774 180.0
HFD1_k127_153107_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003709 231.0
HFD1_k127_153107_1 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000000000002844 194.0
HFD1_k127_153595_0 type II secretion system protein K12511 - - 0.0000000000000000000000000000000000000000000000000000005675 205.0
HFD1_k127_153595_1 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000002554 199.0
HFD1_k127_153595_2 PFAM Type II secretion system protein E K02283,K03609 - - 0.0000000000000000000000000818 108.0
HFD1_k127_153595_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000008451 100.0
HFD1_k127_153595_4 ATPases associated with a variety of cellular activities - - - 0.000000003527 61.0
HFD1_k127_153995_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 321.0
HFD1_k127_1553240_0 cobalamin-transporting ATPase activity K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 448.0
HFD1_k127_1553240_1 PFAM ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000004471 110.0
HFD1_k127_156603_0 glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000001531 253.0
HFD1_k127_156603_1 3' exoribonuclease, RNase T-like K03656,K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000001511 188.0
HFD1_k127_157876_0 Glycosyl transferases group 1 K19424 - - 0.000000000000000000000000000000000000000000000000000000000001446 214.0
HFD1_k127_157876_1 O-Antigen Polymerase K02847 - - 0.00000000023 69.0
HFD1_k127_1607413_0 Copper amine oxidase N-terminal domain - - - 0.00000000004402 76.0
HFD1_k127_1610096_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 331.0
HFD1_k127_1612652_0 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000003469 130.0
HFD1_k127_1612652_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000001256 99.0
HFD1_k127_1612652_2 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000007023 86.0
HFD1_k127_161415_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 421.0
HFD1_k127_161415_1 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 375.0
HFD1_k127_161415_10 Copper binding proteins, plastocyanin/azurin family - - - 0.000007965 58.0
HFD1_k127_161415_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006634 274.0
HFD1_k127_161415_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000001406 261.0
HFD1_k127_161415_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000009062 193.0
HFD1_k127_161415_5 NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000273 181.0
HFD1_k127_161415_6 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000003569 153.0
HFD1_k127_161415_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000002528 145.0
HFD1_k127_161415_8 - - - - 0.00000000000000000000000000000001611 141.0
HFD1_k127_161415_9 - - - - 0.000000000000000000000000000009146 121.0
HFD1_k127_1614663_0 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 382.0
HFD1_k127_1614663_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 386.0
HFD1_k127_1614663_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001943 248.0
HFD1_k127_1614679_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 381.0
HFD1_k127_1616200_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000001803 172.0
HFD1_k127_1616200_1 Transposase DDE domain - - - 0.00000000000000000002077 95.0
HFD1_k127_1616200_2 Transposase - - - 0.000000000000001203 86.0
HFD1_k127_1616200_3 PFAM Transposase DDE domain - - - 0.000001436 56.0
HFD1_k127_1618596_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001537 287.0
HFD1_k127_1618596_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002369 241.0
HFD1_k127_1618596_2 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000000000003315 178.0
HFD1_k127_1618596_3 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000104 184.0
HFD1_k127_1618596_4 ADP binding - - - 0.0000000000000000000000000000001028 144.0
HFD1_k127_1618596_5 BlaR1 peptidase M56 - - - 0.00000000002084 72.0
HFD1_k127_1618596_6 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0006809 48.0
HFD1_k127_1619982_0 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 338.0
HFD1_k127_1619982_1 PFAM fumarate lyase K01679 - 4.2.1.2 0.000000000000004616 76.0
HFD1_k127_1622756_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 521.0
HFD1_k127_1629566_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 3.493e-203 650.0
HFD1_k127_1629566_1 PFAM amidohydrolase - - - 5.493e-196 628.0
HFD1_k127_1629566_2 VanZ like family - - - 0.00007076 55.0
HFD1_k127_1629566_3 VanZ like family - - - 0.00009354 55.0
HFD1_k127_1631382_0 RecQ zinc-binding K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 335.0
HFD1_k127_1631382_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - 0.00000000000000004447 82.0
HFD1_k127_1631786_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 301.0
HFD1_k127_1635368_0 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 0.0000000000000000000000000000000000000000000000000000006954 210.0
HFD1_k127_1635368_1 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000001251 109.0
HFD1_k127_1637886_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 460.0
HFD1_k127_1637886_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000215 191.0
HFD1_k127_1639578_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 346.0
HFD1_k127_1639578_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001307 270.0
HFD1_k127_1639578_2 Cys Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000002526 64.0
HFD1_k127_1642879_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001864 287.0
HFD1_k127_1642879_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000009527 224.0
HFD1_k127_1642879_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000008849 179.0
HFD1_k127_1643112_0 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009165 253.0
HFD1_k127_1649210_0 Uncharacterised protein family (UPF0182) K09118 - - 5.928e-216 693.0
HFD1_k127_1649210_1 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000001808 105.0
HFD1_k127_1649696_0 Amidohydrolase family K01466 - 3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 507.0
HFD1_k127_1649696_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 476.0
HFD1_k127_1649696_2 Belongs to the allantoicase family K01477 - 3.5.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 396.0
HFD1_k127_1649696_3 OHCU decarboxylase K16840 - 4.1.1.97 0.000000000001381 69.0
HFD1_k127_1649696_4 DinB family - - - 0.0004458 49.0
HFD1_k127_1653630_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 465.0
HFD1_k127_1653630_1 Methyltransferase small domain K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000006677 184.0
HFD1_k127_1653630_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000015 147.0
HFD1_k127_1653630_3 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000000000000006825 111.0
HFD1_k127_1655464_0 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 327.0
HFD1_k127_1655464_1 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001366 239.0
HFD1_k127_1655464_2 Hexapeptide repeat of succinyl-transferase K00661 - 2.3.1.79 0.0000000000000000000000000000000000006098 146.0
HFD1_k127_1655464_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000872 130.0
HFD1_k127_1655464_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000001356 141.0
HFD1_k127_1655464_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000001317 134.0
HFD1_k127_1655464_6 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000004554 94.0
HFD1_k127_1655464_7 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000000008507 82.0
HFD1_k127_1655464_8 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000004832 72.0
HFD1_k127_1655464_9 40-residue YVTN family beta-propeller repeat - - - 0.0000000005254 72.0
HFD1_k127_1658207_0 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000001243 78.0
HFD1_k127_1658207_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000003547 66.0
HFD1_k127_1660506_0 - - - - 0.000000000000000000000000000000000000000000004997 177.0
HFD1_k127_1661156_0 Transposase K07493 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 551.0
HFD1_k127_1661156_1 PFAM Integrase, catalytic K07497 - - 0.0009645 43.0
HFD1_k127_166374_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 375.0
HFD1_k127_166374_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000004241 152.0
HFD1_k127_166374_2 Thioesterase superfamily - - - 0.0000000000000000000477 95.0
HFD1_k127_1666190_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1431.0
HFD1_k127_1666190_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 577.0
HFD1_k127_1666190_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087,K16055 GO:0003674,GO:0003824,GO:0004805,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044464,GO:0046351,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:1901576 2.4.1.15,3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 568.0
HFD1_k127_1666190_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 335.0
HFD1_k127_1666190_4 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000001428 193.0
HFD1_k127_1666190_5 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000007536 137.0
HFD1_k127_1666190_6 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000005588 113.0
HFD1_k127_1666190_7 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000006278 80.0
HFD1_k127_1666190_8 Tetratricopeptide repeat - - - 0.000003503 58.0
HFD1_k127_1671060_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 494.0
HFD1_k127_1671060_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000002526 115.0
HFD1_k127_1671060_2 Universal stress protein - - - 0.000000003314 64.0
HFD1_k127_1677376_0 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 320.0
HFD1_k127_1677376_1 - - - - 0.0004976 52.0
HFD1_k127_1681613_0 Methyl-accepting chemotaxis protein K02660,K11525 - - 0.00000002306 66.0
HFD1_k127_1681613_1 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0000001815 53.0
HFD1_k127_1684950_0 RNA-directed DNA polymerase (reverse transcriptase) K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 471.0
HFD1_k127_1684950_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000002282 66.0
HFD1_k127_168638_0 Phenazine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 365.0
HFD1_k127_168638_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000005442 269.0
HFD1_k127_168638_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000116 266.0
HFD1_k127_168638_3 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000004536 141.0
HFD1_k127_168638_5 FtsX-like permease family K02004 - - 0.00004754 45.0
HFD1_k127_1690602_0 Translation elongation factor K03833 - - 0.000000000000000000000000001985 119.0
HFD1_k127_1690602_1 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000002243 83.0
HFD1_k127_1695405_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 451.0
HFD1_k127_1695405_1 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000003452 160.0
HFD1_k127_1695405_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K21600 - - 0.00000000000000000000000000000000004857 136.0
HFD1_k127_1695405_3 mercury ion transmembrane transporter activity - - - 0.0000000000000000003146 91.0
HFD1_k127_1695405_4 Winged helix-turn helix - - - 0.00000001285 59.0
HFD1_k127_1696545_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008526 286.0
HFD1_k127_1696545_1 DoxX K15977 - - 0.000000003939 58.0
HFD1_k127_17003_0 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 413.0
HFD1_k127_17003_1 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000101 205.0
HFD1_k127_1701627_0 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000521 235.0
HFD1_k127_1701627_1 23S rRNA-intervening sequence protein - - - 0.0000000000000001934 84.0
HFD1_k127_1703116_0 DNA-directed DNA polymerase K02337,K14162 - 2.7.7.7 1.184e-256 825.0
HFD1_k127_1708624_0 Nicastrin K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 350.0
HFD1_k127_1708624_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000164 231.0
HFD1_k127_1709431_0 Nicastrin K01301 - 3.4.17.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 450.0
HFD1_k127_1709431_1 amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 371.0
HFD1_k127_1717266_0 DNA polymerase alpha chain like domain K02347 - - 0.00000000000000000000000000000000000000000000000008356 187.0
HFD1_k127_1717266_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000323 117.0
HFD1_k127_1720568_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000001189 141.0
HFD1_k127_1720568_1 DDE superfamily endonuclease - - - 0.0000000000000001322 80.0
HFD1_k127_1720568_2 ABC transporter K06147,K06148 - - 0.00000005894 54.0
HFD1_k127_1720568_3 transposition - - - 0.00004682 47.0
HFD1_k127_1732120_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.534e-209 676.0
HFD1_k127_1732120_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000002394 230.0
HFD1_k127_1732120_2 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000003999 70.0
HFD1_k127_1736294_0 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003247 271.0
HFD1_k127_1736294_1 PFAM CBS domain containing protein K03699 - - 0.00002122 57.0
HFD1_k127_1736885_0 Putative porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001942 261.0
HFD1_k127_173951_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 569.0
HFD1_k127_173951_1 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 542.0
HFD1_k127_1740012_0 peptidase activity, acting on L-amino acid peptides K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 323.0
HFD1_k127_1740012_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001001 297.0
HFD1_k127_1740012_2 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007485 274.0
HFD1_k127_1740012_3 xylanase chitin deacetylase - - - 0.0000000000000000000000000000000000000000000003224 176.0
HFD1_k127_1740012_4 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000002048 156.0
HFD1_k127_1740553_0 Ndr family - - - 0.0000000000000000000000000000000000000000000000000000000007638 210.0
HFD1_k127_1740553_1 4Fe-4S binding domain - - - 0.000000000000000000000000025 108.0
HFD1_k127_1740992_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000001186 145.0
HFD1_k127_1740992_1 Surface antigen K07277,K07278 - - 0.00000000000000000000002316 112.0
HFD1_k127_1742206_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 336.0
HFD1_k127_1742206_1 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000001192 205.0
HFD1_k127_1742206_2 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000001058 85.0
HFD1_k127_1742206_3 positive regulation of growth rate - - - 0.0000000000001207 83.0
HFD1_k127_1754117_0 Cell cycle protein K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 456.0
HFD1_k127_1754117_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 372.0
HFD1_k127_175690_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 576.0
HFD1_k127_175690_1 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 457.0
HFD1_k127_175690_2 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001067 238.0
HFD1_k127_175690_3 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000002408 222.0
HFD1_k127_175690_4 ATP binding - - - 0.00000000000000000000000000000005681 144.0
HFD1_k127_175690_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000001572 128.0
HFD1_k127_1757378_0 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001248 282.0
HFD1_k127_1757378_1 - - - - 0.000000000000000000000000000000000002981 145.0
HFD1_k127_1757422_0 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 394.0
HFD1_k127_1762770_0 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 284.0
HFD1_k127_1762770_1 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000004766 277.0
HFD1_k127_1766412_0 ABC transporter, transmembrane region K06147 - - 0.000000000000000000000000000000000000000001062 172.0
HFD1_k127_1771098_0 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000001058 206.0
HFD1_k127_1771098_1 Winged helix-turn helix - - - 0.0000000000000000000000008213 110.0
HFD1_k127_1771098_2 Winged helix-turn helix - - - 0.00000000005621 65.0
HFD1_k127_1772270_0 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 439.0
HFD1_k127_1772270_1 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000926 271.0
HFD1_k127_1772270_2 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000111 215.0
HFD1_k127_1772270_3 - - - - 0.000000000000000000000000000000000000000003885 173.0
HFD1_k127_17731_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 452.0
HFD1_k127_17731_1 S4 RNA-binding domain K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000003438 193.0
HFD1_k127_1775866_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 451.0
HFD1_k127_1775866_1 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000000000000002512 189.0
HFD1_k127_1775866_2 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000001036 173.0
HFD1_k127_1777403_0 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 309.0
HFD1_k127_1777403_1 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000008625 260.0
HFD1_k127_1777403_2 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.00000000000000000000008098 98.0
HFD1_k127_1777471_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 339.0
HFD1_k127_1777471_1 gluconolactonase activity - - - 0.0000000000000000000000000003518 127.0
HFD1_k127_1778834_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 387.0
HFD1_k127_1782608_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006482 245.0
HFD1_k127_1782608_1 Protein kinase domain K12132 - 2.7.11.1 0.00000009385 57.0
HFD1_k127_1785479_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000312 179.0
HFD1_k127_1797710_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 417.0
HFD1_k127_1797710_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000006272 148.0
HFD1_k127_1797710_2 chlorophyll binding K02040,K03286,K21218 - - 0.0000000005123 68.0
HFD1_k127_1799750_0 Thioesterase superfamily K07107 - - 0.00000000000000000000000742 106.0
HFD1_k127_1799750_1 Positively regulates the dhaKLM operon from a sigma-70 promoter K05880 GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000009034 57.0
HFD1_k127_1810846_0 Transposase - - - 4.005e-267 835.0
HFD1_k127_1810846_1 BMC - - - 0.00000000000000000000000008616 117.0
HFD1_k127_1810846_2 Transposase - - - 0.0001091 49.0
HFD1_k127_1811361_0 LssY C-terminus - - - 0.0001699 51.0
HFD1_k127_182089_0 Peptidase, M61 - - - 0.000000000000000000000000000000000000000000000000000006049 204.0
HFD1_k127_1823618_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 373.0
HFD1_k127_1828507_0 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 454.0
HFD1_k127_1828507_1 - - - - 0.0000000000000000000000000000000003343 135.0
HFD1_k127_1843576_0 AAA ATPase domain - - - 0.00000000000000002987 94.0
HFD1_k127_1843674_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 562.0
HFD1_k127_1843674_1 Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000001292 273.0
HFD1_k127_1843674_2 membrane transporter protein K07090 - - 0.0000000000000000000000000001973 117.0
HFD1_k127_1843674_3 Euchromatic histone-lysine N-methyltransferase 2 K11420 GO:0000003,GO:0000122,GO:0000228,GO:0000280,GO:0000785,GO:0000790,GO:0000976,GO:0000977,GO:0001012,GO:0001067,GO:0001708,GO:0002039,GO:0002165,GO:0002682,GO:0002697,GO:0002831,GO:0003006,GO:0003008,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005705,GO:0006139,GO:0006259,GO:0006275,GO:0006304,GO:0006305,GO:0006306,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0007049,GO:0007059,GO:0007127,GO:0007129,GO:0007130,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007399,GO:0007444,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007614,GO:0007616,GO:0007626,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008345,GO:0008757,GO:0009267,GO:0009410,GO:0009566,GO:0009605,GO:0009719,GO:0009725,GO:0009755,GO:0009791,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010424,GO:0010468,GO:0010506,GO:0010507,GO:0010556,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0010639,GO:0010720,GO:0010769,GO:0010770,GO:0010948,GO:0010975,GO:0010976,GO:0014070,GO:0016043,GO:0016241,GO:0016242,GO:0016278,GO:0016279,GO:0016569,GO:0016570,GO:0016571,GO:0016604,GO:0016607,GO:0016740,GO:0016741,GO:0018022,GO:0018024,GO:0018027,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019904,GO:0019953,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0023052,GO:0030154,GO:0030182,GO:0030518,GO:0030522,GO:0030534,GO:0030537,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0031344,GO:0031346,GO:0031347,GO:0031399,GO:0031401,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032259,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032776,GO:0032870,GO:0033043,GO:0033044,GO:0033554,GO:0033993,GO:0034641,GO:0034968,GO:0035075,GO:0035076,GO:0035220,GO:0035265,GO:0035295,GO:0035690,GO:0036166,GO:0036211,GO:0036314,GO:0036315,GO:0040007,GO:0042054,GO:0042220,GO:0042221,GO:0042493,GO:0042594,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043279,GO:0043401,GO:0043412,GO:0043414,GO:0043565,GO:0043900,GO:0044030,GO:0044085,GO:0044087,GO:0044088,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0044728,GO:0045132,GO:0045143,GO:0045165,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045786,GO:0045892,GO:0045934,GO:0046483,GO:0046958,GO:0046959,GO:0046974,GO:0046976,GO:0048148,GO:0048232,GO:0048285,GO:0048468,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048589,GO:0048609,GO:0048663,GO:0048665,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050688,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051052,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051276,GO:0051321,GO:0051567,GO:0051569,GO:0051570,GO:0051574,GO:0051704,GO:0051716,GO:0051726,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0060359,GO:0060429,GO:0061647,GO:0061982,GO:0065007,GO:0070013,GO:0070192,GO:0070193,GO:0070316,GO:0070317,GO:0070734,GO:0070742,GO:0070887,GO:0071242,GO:0071310,GO:0071312,GO:0071314,GO:0071383,GO:0071390,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071496,GO:0071704,GO:0071840,GO:0072347,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097305,GO:0097306,GO:0098687,GO:0098813,GO:0120035,GO:0140013,GO:0140096,GO:1900006,GO:1900109,GO:1900111,GO:1901360,GO:1901363,GO:1901564,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902115,GO:1902116,GO:1902275,GO:1902679,GO:1902902,GO:1903046,GO:1903506,GO:1903507,GO:1905269,GO:1990837,GO:1990841,GO:2000026,GO:2000112,GO:2000113,GO:2000785,GO:2001141,GO:2001252 2.1.1.43 0.00000000000007856 80.0
HFD1_k127_1852217_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 2.559e-232 741.0
HFD1_k127_1852217_1 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004674 289.0
HFD1_k127_1852217_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000007119 228.0
HFD1_k127_1854593_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001098 301.0
HFD1_k127_1854593_1 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001783 201.0
HFD1_k127_1859170_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 556.0
HFD1_k127_1863942_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
HFD1_k127_1863942_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 336.0
HFD1_k127_1863942_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000005554 232.0
HFD1_k127_1863942_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000006531 228.0
HFD1_k127_1863942_4 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000002336 222.0
HFD1_k127_1863942_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000001722 205.0
HFD1_k127_1863942_6 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000006532 114.0
HFD1_k127_1863942_7 Glycosyl transferase family 2 - - - 0.00000000000000000000000177 112.0
HFD1_k127_1863942_8 Acylphosphatase K01512 - 3.6.1.7 0.000000000000005211 80.0
HFD1_k127_1863942_9 protein trimerization - - - 0.0000006241 59.0
HFD1_k127_1866443_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 363.0
HFD1_k127_1866443_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000001335 184.0
HFD1_k127_1866443_2 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000187 125.0
HFD1_k127_1866443_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.000000000000002321 87.0
HFD1_k127_1867738_0 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 589.0
HFD1_k127_1867738_1 - - - - 0.0000000000000000000006756 101.0
HFD1_k127_1867738_2 AcrB/AcrD/AcrF family - - - 0.000000000000003598 78.0
HFD1_k127_1888235_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 418.0
HFD1_k127_1888235_1 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 396.0
HFD1_k127_1893088_0 - - - - 0.00000000000000000000000000000000000000000000000000000000007941 210.0
HFD1_k127_1893088_1 - - - - 0.000000000000000000000000000000362 138.0
HFD1_k127_1893088_2 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.0000000000007849 75.0
HFD1_k127_1897524_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 458.0
HFD1_k127_1905082_0 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000004676 207.0
HFD1_k127_1905082_1 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000002085 118.0
HFD1_k127_1909653_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 417.0
HFD1_k127_1909653_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 332.0
HFD1_k127_1909653_2 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000008748 184.0
HFD1_k127_1909653_3 - - - - 0.000003301 55.0
HFD1_k127_1921620_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.105e-305 960.0
HFD1_k127_1921620_1 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 304.0
HFD1_k127_1921620_2 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007009 277.0
HFD1_k127_1925514_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 6.3e-236 739.0
HFD1_k127_1925514_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000007952 173.0
HFD1_k127_1930189_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 502.0
HFD1_k127_1930189_1 C-terminal AAA-associated domain K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 351.0
HFD1_k127_1930189_2 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000971 186.0
HFD1_k127_193802_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 325.0
HFD1_k127_1945226_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000009733 254.0
HFD1_k127_1945226_1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000001179 130.0
HFD1_k127_1945226_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000004099 84.0
HFD1_k127_1945275_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 378.0
HFD1_k127_1945275_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000003738 56.0
HFD1_k127_195112_0 Zn peptidase - - - 0.00000000000000000000000000000004204 137.0
HFD1_k127_195112_1 response to heat K03695,K03696,K03697,K03798 - - 0.0000000000000000000000000009476 119.0
HFD1_k127_1965823_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 579.0
HFD1_k127_1968298_0 Part of the ABC transporter FtsEX involved in K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000003929 233.0
HFD1_k127_1968298_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000002677 187.0
HFD1_k127_196845_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000559 278.0
HFD1_k127_196845_1 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000000000000001564 154.0
HFD1_k127_196845_2 Uncharacterized conserved protein (COG2071) K09166 - - 0.000000000000000000004396 107.0
HFD1_k127_2008711_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 371.0
HFD1_k127_2008711_1 Protein of unknown function (DUF503) K09764 - - 0.000000000000003944 76.0
HFD1_k127_2012766_0 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 425.0
HFD1_k127_2012766_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 394.0
HFD1_k127_2012766_2 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000001524 233.0
HFD1_k127_2012766_3 L-lysine catabolic process to acetate K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000003396 224.0
HFD1_k127_2012766_4 HAD-hyrolase-like K19270 - 3.1.3.23 0.0000000000000000000000000000000000000000000000003894 189.0
HFD1_k127_2012766_5 Outer membrane protein beta-barrel domain - - - 0.000009895 55.0
HFD1_k127_2013074_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 357.0
HFD1_k127_2015429_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 541.0
HFD1_k127_2015429_1 MacB-like periplasmic core domain - - - 0.00000002672 55.0
HFD1_k127_2018648_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000003715 227.0
HFD1_k127_2018648_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000007219 141.0
HFD1_k127_2018648_2 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000002824 134.0
HFD1_k127_2018648_3 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000006746 67.0
HFD1_k127_2042482_0 Amylo-alpha-1,6-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 356.0
HFD1_k127_2042482_1 TOBE domain K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 292.0
HFD1_k127_2042482_2 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000146 248.0
HFD1_k127_2064578_0 Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 330.0
HFD1_k127_2064578_1 phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001173 242.0
HFD1_k127_2064578_2 Phosphoesterase K07095 - - 0.0000000000000000000000000000000000001475 145.0
HFD1_k127_2068564_0 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002865 202.0
HFD1_k127_2068564_1 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000004131 186.0
HFD1_k127_2068564_2 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000003378 141.0
HFD1_k127_2086368_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001962 258.0
HFD1_k127_2104241_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 352.0
HFD1_k127_2104241_1 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 318.0
HFD1_k127_2104241_2 PAS domain - - - 0.00000000000000000000000000000000000000000000000000003783 192.0
HFD1_k127_2116750_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 392.0
HFD1_k127_2116750_1 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
HFD1_k127_2116750_2 Transposase - - - 0.0000000000000000000000000000000000000003821 151.0
HFD1_k127_2118931_0 Flavin containing amine oxidoreductase - - - 3.867e-238 751.0
HFD1_k127_2118931_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 422.0
HFD1_k127_2118931_2 Glycine cleavage T-protein C-terminal barrel domain - - - 0.0000000000000000000000000000000001633 134.0
HFD1_k127_2118931_3 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.000003126 53.0
HFD1_k127_2128683_0 transposition, DNA-mediated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 331.0
HFD1_k127_2128683_1 Resolvase, N terminal domain - - - 0.00011 53.0
HFD1_k127_2141626_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 362.0
HFD1_k127_2141626_1 ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000358 226.0
HFD1_k127_2141626_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000005673 210.0
HFD1_k127_2141626_3 xylanase chitin deacetylase - - - 0.00000000000000000000000000000000000000000001002 172.0
HFD1_k127_214170_0 Ribosomal protein S2 K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 362.0
HFD1_k127_214170_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 259.0
HFD1_k127_214170_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000001032 229.0
HFD1_k127_2159943_0 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000004661 149.0
HFD1_k127_2159943_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000005832 83.0
HFD1_k127_2159943_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000001597 66.0
HFD1_k127_2159943_3 Amino acid permease K03294 - - 0.000003812 51.0
HFD1_k127_2171076_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 378.0
HFD1_k127_2171076_1 COG0348 Polyferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009669 288.0
HFD1_k127_2171076_2 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 0.000000000000000000000000000000000000001261 150.0
HFD1_k127_2171076_3 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.000000000000000000000000000000001896 136.0
HFD1_k127_2171076_4 cytochrome oxidase maturation protein cbb3-type - - - 0.00005595 55.0
HFD1_k127_2178875_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 476.0
HFD1_k127_2178875_1 transposition K07497 - - 0.0000000000000007035 78.0
HFD1_k127_2198306_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000293 132.0
HFD1_k127_2198306_1 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.00000000000000008693 93.0
HFD1_k127_2198306_2 Protein of unknown function, DUF255 K06888 - - 0.0000007778 53.0
HFD1_k127_2200028_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000005393 248.0
HFD1_k127_2200028_1 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000001145 234.0
HFD1_k127_2200028_2 CcmB protein K02194 - - 0.000000000000000000000000000000000000000000000000000000005204 208.0
HFD1_k127_2200028_3 water channel activity K02440,K06188,K09874 - - 0.0000000000000000000000000000000000000000000000000001545 197.0
HFD1_k127_2200028_4 AAA domain, putative AbiEii toxin, Type IV TA system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000001547 166.0
HFD1_k127_2200028_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000002456 81.0
HFD1_k127_2204544_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 429.0
HFD1_k127_2205200_0 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 329.0
HFD1_k127_2205200_1 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 301.0
HFD1_k127_2205200_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000146 229.0
HFD1_k127_2205200_3 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000003421 230.0
HFD1_k127_2205200_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000001601 196.0
HFD1_k127_2205200_5 Sporulation related domain - - - 0.0000000000001791 83.0
HFD1_k127_2216776_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 351.0
HFD1_k127_2216776_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004948 264.0
HFD1_k127_2216776_2 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000038 214.0
HFD1_k127_2216776_3 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000003729 155.0
HFD1_k127_2216776_4 Transposase DDE domain - - - 0.000000000000000000000002061 113.0
HFD1_k127_2226144_0 cellulose binding - - - 2.267e-208 680.0
HFD1_k127_2226144_1 PFAM magnesium chelatase ChlI subunit K07391 - - 1.136e-198 631.0
HFD1_k127_2226144_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000149 209.0
HFD1_k127_2226144_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000005217 127.0
HFD1_k127_2226144_4 - - - - 0.00000000000000000000000139 111.0
HFD1_k127_2226144_5 Carboxypeptidase regulatory-like domain K02014 - - 0.0000000000000000000001198 108.0
HFD1_k127_2226144_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000001971 100.0
HFD1_k127_2226144_7 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000004557 69.0
HFD1_k127_2226144_8 - - - - 0.0000004191 64.0
HFD1_k127_2226144_9 PEGA domain - - - 0.000001854 58.0
HFD1_k127_2226145_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 578.0
HFD1_k127_2226145_1 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000001491 239.0
HFD1_k127_2226145_2 water channel activity K02440,K06188,K09874 - - 0.00000000000000000000000000000000000000000000000000006068 198.0
HFD1_k127_2226145_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000001378 147.0
HFD1_k127_2226145_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000001476 132.0
HFD1_k127_2246579_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 402.0
HFD1_k127_227713_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000002986 181.0
HFD1_k127_227713_1 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000001225 128.0
HFD1_k127_227725_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000001369 149.0
HFD1_k127_227725_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00001096 50.0
HFD1_k127_2284512_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 363.0
HFD1_k127_2284512_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 328.0
HFD1_k127_2306101_0 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003347 246.0
HFD1_k127_2306101_1 - - - - 0.00000000000248 74.0
HFD1_k127_2346926_0 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 558.0
HFD1_k127_2346926_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000004551 180.0
HFD1_k127_2346926_2 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000008271 174.0
HFD1_k127_2346926_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000001189 112.0
HFD1_k127_2381603_0 Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 326.0
HFD1_k127_2386913_0 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000001338 173.0
HFD1_k127_2386913_1 - - - - 0.00002409 48.0
HFD1_k127_2396054_0 phosphorelay signal transduction system K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000004826 184.0
HFD1_k127_2396054_1 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000002311 182.0
HFD1_k127_2400055_0 Alpha-glucosidase K01187,K21574 - 3.2.1.20,3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 527.0
HFD1_k127_2400055_1 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000197 123.0
HFD1_k127_2411480_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 409.0
HFD1_k127_2411480_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 399.0
HFD1_k127_2411480_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002519 249.0
HFD1_k127_2411480_3 PTS system sorbose subfamily IIB component K19507 - - 0.000000000000000000000000000000000000000000000000000000001883 208.0
HFD1_k127_2411480_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000007348 156.0
HFD1_k127_2411480_5 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.000000000000000000000000000000002399 144.0
HFD1_k127_2411480_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000006326 122.0
HFD1_k127_2411480_7 PTS system sorbose-specific iic component K02795 - - 0.000000000000000009958 94.0
HFD1_k127_2411480_8 system, fructose subfamily IIA component K02793,K02794 - 2.7.1.191 0.00000002117 61.0
HFD1_k127_2411736_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000005517 201.0
HFD1_k127_2411736_1 M61 glycyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000002181 198.0
HFD1_k127_2411882_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.297e-201 643.0
HFD1_k127_2411882_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000008223 244.0
HFD1_k127_2415108_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.268e-230 722.0
HFD1_k127_2415760_0 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 424.0
HFD1_k127_2419264_0 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001768 279.0
HFD1_k127_2419264_1 permease - - - 0.00000000000000000000000000000008846 139.0
HFD1_k127_2420684_0 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000004303 184.0
HFD1_k127_2420684_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000001855 165.0
HFD1_k127_2420684_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000004788 118.0
HFD1_k127_2420684_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000006727 48.0
HFD1_k127_2420709_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005235 259.0
HFD1_k127_2420709_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000003847 158.0
HFD1_k127_2420709_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000029 58.0
HFD1_k127_2420709_3 - - - - 0.00005834 50.0
HFD1_k127_2421929_0 EstX protein - - - 0.0000000000000000000000000001842 128.0
HFD1_k127_2421929_1 4Fe-4S binding domain K11473 - - 0.00000000000000233 77.0
HFD1_k127_2425203_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 334.0
HFD1_k127_2425203_1 Putative ABC exporter - - - 0.000000000003694 73.0
HFD1_k127_2425822_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 456.0
HFD1_k127_2425822_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000003226 135.0
HFD1_k127_2425822_2 - - - - 0.000000002439 60.0
HFD1_k127_2427994_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 370.0
HFD1_k127_2427994_1 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000001839 74.0
HFD1_k127_2427994_2 Domain of unknown function (DUF362) - - - 0.00000003595 56.0
HFD1_k127_2429302_0 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000002507 226.0
HFD1_k127_2429302_1 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000000006306 82.0
HFD1_k127_242997_0 Belongs to the 'phage' integrase family - - - 1.824e-205 648.0
HFD1_k127_242997_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000002641 127.0
HFD1_k127_242997_2 - - - - 0.0000000000000000001345 91.0
HFD1_k127_2432152_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 567.0
HFD1_k127_2435151_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000002029 154.0
HFD1_k127_2435151_1 DinB family - - - 0.000000000000000000000000000000000009091 143.0
HFD1_k127_2435151_2 30S ribosomal protein Thx K19033 - - 0.000004673 49.0
HFD1_k127_2440288_0 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 394.0
HFD1_k127_2440288_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 298.0
HFD1_k127_2440288_2 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 286.0
HFD1_k127_2440288_3 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000002122 216.0
HFD1_k127_2440288_4 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000002066 220.0
HFD1_k127_2440946_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000007068 175.0
HFD1_k127_2440946_1 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000002191 60.0
HFD1_k127_2440946_2 siderophore transport K02014 - - 0.000003752 49.0
HFD1_k127_2440946_3 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0005888 50.0
HFD1_k127_2443310_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 386.0
HFD1_k127_2443310_1 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 305.0
HFD1_k127_2443310_2 polysaccharide deacetylase K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000001937 226.0
HFD1_k127_2443849_0 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000161 215.0
HFD1_k127_2443849_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0006973 45.0
HFD1_k127_2445544_0 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - 0.00000000000000000000000000000000000000000000000000000000000000004306 229.0
HFD1_k127_2445544_1 Cytochrome c - - - 0.00000284 54.0
HFD1_k127_2445544_2 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - 0.00001018 55.0
HFD1_k127_2446231_0 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000001076 117.0
HFD1_k127_2446231_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0000007898 56.0
HFD1_k127_2448900_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 308.0
HFD1_k127_2448900_1 - - - - 0.0000001252 58.0
HFD1_k127_2449454_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 528.0
HFD1_k127_2449454_1 manually curated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 412.0
HFD1_k127_2449454_2 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.000000000000000000000000000000000000000000000000002442 185.0
HFD1_k127_2449454_3 - - - - 0.00000000000000000000000000000000000000000004589 168.0
HFD1_k127_2449454_4 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000003872 97.0
HFD1_k127_2449454_5 DDE superfamily endonuclease - - - 0.000000002874 64.0
HFD1_k127_2449454_6 B-1 B cell differentiation - - - 0.0000002753 52.0
HFD1_k127_2455649_0 long-chain fatty acid transporting porin activity K09806 - - 0.00000000000000000000000000000000000000000000000000000000001091 214.0
HFD1_k127_2455649_1 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000425 130.0
HFD1_k127_2456783_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004135 256.0
HFD1_k127_2456783_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000562 208.0
HFD1_k127_2456783_2 Beta-lactamase - - - 0.0000000000000000005213 87.0
HFD1_k127_2456783_3 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000001207 61.0
HFD1_k127_2457346_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 466.0
HFD1_k127_2457346_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 353.0
HFD1_k127_2457346_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 304.0
HFD1_k127_2457346_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000001289 211.0
HFD1_k127_2457346_4 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000002059 140.0
HFD1_k127_2457346_5 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000004135 98.0
HFD1_k127_2464324_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 451.0
HFD1_k127_2464324_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000009453 192.0
HFD1_k127_2464324_2 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000002013 148.0
HFD1_k127_2464324_3 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000002882 96.0
HFD1_k127_2464324_4 Transposase - - - 0.00000000000003363 83.0
HFD1_k127_2464324_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000001026 57.0
HFD1_k127_2476935_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000004461 232.0
HFD1_k127_2476935_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000224 134.0
HFD1_k127_2476974_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000009187 226.0
HFD1_k127_2476974_1 curli production assembly transport component CsgG K04087 - - 0.0000000000000000000000000000000000000000000009544 181.0
HFD1_k127_2476974_2 - - - - 0.00000000002902 75.0
HFD1_k127_2483455_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0000000000000000000000000000000000000000000000000000000000000002843 227.0
HFD1_k127_248356_0 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 397.0
HFD1_k127_2490577_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000005746 224.0
HFD1_k127_2490577_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000001353 218.0
HFD1_k127_2490577_2 polysaccharide catabolic process K03478 - 3.5.1.105 0.00000000002473 69.0
HFD1_k127_2493568_0 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003364 293.0
HFD1_k127_2493568_1 Endonuclease related to archaeal Holliday junction resolvase - - - 0.00000000000000000000000000002108 123.0
HFD1_k127_2493568_2 TonB-dependent receptor - - - 0.00000000138 70.0
HFD1_k127_2493568_3 EamA-like transporter family - - - 0.0000005213 61.0
HFD1_k127_2501755_0 Acyclic terpene utilisation family protein AtuA - - - 9.081e-203 647.0
HFD1_k127_2501755_1 - - - - 0.00000000000000000000000000000000000000001389 164.0
HFD1_k127_2501755_2 Enoyl-CoA hydratase/isomerase K01692,K13766,K13779 - 4.2.1.17,4.2.1.18,4.2.1.57 0.00000000000000000000000000000339 130.0
HFD1_k127_2503147_0 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 317.0
HFD1_k127_2503147_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000003137 145.0
HFD1_k127_2504365_0 LVIVD repeat - - - 9.269e-223 709.0
HFD1_k127_2504365_1 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000000000000000000001714 224.0
HFD1_k127_2504365_2 LVIVD repeat - - - 0.000000000000000000000000000009913 122.0
HFD1_k127_2507835_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 571.0
HFD1_k127_2507835_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 518.0
HFD1_k127_2507835_2 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000001121 263.0
HFD1_k127_2507835_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000482 247.0
HFD1_k127_2507835_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000005118 173.0
HFD1_k127_2507835_5 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.00000001488 56.0
HFD1_k127_2507835_6 Zinc finger domain - - - 0.00000001519 64.0
HFD1_k127_2507835_7 - K01822 - 5.3.3.1 0.00000002526 63.0
HFD1_k127_2508484_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.183e-224 726.0
HFD1_k127_2508484_1 - - - - 0.000000004767 65.0
HFD1_k127_2508484_2 Regulatory protein RecX K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.00001016 52.0
HFD1_k127_2509055_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 309.0
HFD1_k127_2509055_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000003893 163.0
HFD1_k127_2509055_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000006492 108.0
HFD1_k127_2511644_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 471.0
HFD1_k127_2512801_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 554.0
HFD1_k127_2512801_1 iron-sulfur cluster assembly K07400 - - 0.000000000000000000000000000000000000001358 155.0
HFD1_k127_2513023_0 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 520.0
HFD1_k127_2513023_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 499.0
HFD1_k127_2513023_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 376.0
HFD1_k127_2513023_3 Patatin-like phospholipase - - - 0.00000000000000000000000000000006899 138.0
HFD1_k127_2513023_4 Sulfurtransferase TusA - - - 0.0000000000001351 73.0
HFD1_k127_2515396_0 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 406.0
HFD1_k127_2515396_1 - - - - 0.000000000000000000000001227 104.0
HFD1_k127_2515396_2 Matrixin - - - 0.000000000000002317 84.0
HFD1_k127_2520952_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.491e-278 877.0
HFD1_k127_2520952_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 290.0
HFD1_k127_2520952_2 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000002735 190.0
HFD1_k127_2521875_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 401.0
HFD1_k127_2521875_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 356.0
HFD1_k127_2521875_2 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000002181 109.0
HFD1_k127_2521875_3 nuclear chromosome segregation - - - 0.0000000000000000000000009925 115.0
HFD1_k127_2523348_0 Participates in both transcription termination and antitermination K02600 - - 3.387e-196 619.0
HFD1_k127_2523348_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000004531 80.0
HFD1_k127_2523348_2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family - - - 0.00000000006319 66.0
HFD1_k127_2524886_0 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 337.0
HFD1_k127_2526045_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 347.0
HFD1_k127_2526045_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000004685 99.0
HFD1_k127_2526665_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 537.0
HFD1_k127_2526665_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 379.0
HFD1_k127_2526819_0 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006136 290.0
HFD1_k127_2526819_1 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.00000000000000000000000000000000000000007698 160.0
HFD1_k127_2526819_2 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000002938 59.0
HFD1_k127_2533412_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001338 244.0
HFD1_k127_2533412_1 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000875 207.0
HFD1_k127_2533412_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000001585 183.0
HFD1_k127_2533412_3 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000005096 166.0
HFD1_k127_2533412_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000001267 112.0
HFD1_k127_2542231_0 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000009543 112.0
HFD1_k127_2544245_0 LVIVD repeat - - - 0.000000000000000000000000000000000000002646 165.0
HFD1_k127_2545732_0 Transposase K07485 - - 0.0000000000000000000000000000000000000000000000000002488 197.0
HFD1_k127_2545732_1 Transposase - - - 0.00000000000000000000000000000000264 139.0
HFD1_k127_2545732_2 Transposase DDE domain - - - 0.0000000001835 64.0
HFD1_k127_2547780_0 phosphorelay signal transduction system K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005954 256.0
HFD1_k127_2547780_1 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000001431 166.0
HFD1_k127_2549183_0 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 345.0
HFD1_k127_2549183_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000024 168.0
HFD1_k127_2550848_0 aconitate hydratase K01681 - 4.2.1.3 1.317e-256 801.0
HFD1_k127_2550848_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 402.0
HFD1_k127_2550848_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000005253 193.0
HFD1_k127_2550848_3 - - - - 0.0000000000000000000000000000000000000000001522 162.0
HFD1_k127_2550848_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000005495 160.0
HFD1_k127_2550848_5 ArsC family - - - 0.000000000000000000000000000000000000002742 151.0
HFD1_k127_2550848_6 Thioesterase superfamily - - - 0.000000000000000000000000000002503 131.0
HFD1_k127_2550848_7 - - - - 0.000000000000000000001656 106.0
HFD1_k127_2551324_0 glycosyl transferase group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000000000000005177 196.0
HFD1_k127_2551324_1 Glycosyl transferase family 2 K12984 - - 0.000000000000000004606 86.0
HFD1_k127_2551324_2 PFAM Glycosyl transferase, group 1 K13668 - 2.4.1.346 0.0003772 49.0
HFD1_k127_2553153_0 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000004426 215.0
HFD1_k127_2553153_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000001437 175.0
HFD1_k127_2553153_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000004952 94.0
HFD1_k127_2553153_3 transcriptional regulator - - - 0.0007844 42.0
HFD1_k127_2553896_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1227.0
HFD1_k127_2553896_1 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007038 246.0
HFD1_k127_2553896_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 0.00000000000000001002 95.0
HFD1_k127_2554111_0 PFAM peptidase M55 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000009867 149.0
HFD1_k127_2554111_1 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000225 123.0
HFD1_k127_2554111_2 D-aminopeptidase K16203 - - 0.0000000000000000000000000002429 129.0
HFD1_k127_2554111_3 - - - - 0.00000000000000000000000001377 115.0
HFD1_k127_255788_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000007005 244.0
HFD1_k127_255788_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000406 124.0
HFD1_k127_255788_2 Peptidase M16 - - - 0.0000000000000000000000005188 111.0
HFD1_k127_2560846_0 Invasin, domain 3 K13735 - - 0.00000000000002889 85.0
HFD1_k127_2564463_0 COG4584 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001372 273.0
HFD1_k127_2564463_1 COG4584 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003361 247.0
HFD1_k127_2564463_2 Integrase core domain - - - 0.00000000000000000000000000000001839 139.0
HFD1_k127_2564635_0 aminotransferase class I and II K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 480.0
HFD1_k127_2564635_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 412.0
HFD1_k127_2564635_2 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 339.0
HFD1_k127_2564635_3 NIPSNAP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 293.0
HFD1_k127_2564635_4 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000001212 222.0
HFD1_k127_2564635_5 transcriptional regulator - - - 0.000000000000000136 81.0
HFD1_k127_2569636_0 efflux transmembrane transporter activity K18300,K18308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 384.0
HFD1_k127_2569636_1 transmembrane transporter activity K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001759 265.0
HFD1_k127_2570245_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 8.145e-253 796.0
HFD1_k127_2570245_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000001301 168.0
HFD1_k127_2570245_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000007717 146.0
HFD1_k127_2570245_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.00000000000000000000000000000006092 128.0
HFD1_k127_2570245_4 - - - - 0.0000000000000000000001376 111.0
HFD1_k127_2570245_5 subunit of a heme lyase K02200 - - 0.0000000000000000000002898 108.0
HFD1_k127_2570292_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 529.0
HFD1_k127_2570292_1 Protein of unknown function (DUF1194) K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000009717 238.0
HFD1_k127_2570292_2 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000008797 229.0
HFD1_k127_2570292_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000009463 198.0
HFD1_k127_2570292_4 Oxygen tolerance - - - 0.00000000000000000000000000000000000004897 165.0
HFD1_k127_257625_0 Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 343.0
HFD1_k127_2580942_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 353.0
HFD1_k127_2580942_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 316.0
HFD1_k127_2580942_2 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000958 51.0
HFD1_k127_258108_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 608.0
HFD1_k127_258108_1 CoA binding domain - - - 0.000000000000001233 81.0
HFD1_k127_2589123_0 - - - - 0.000001651 56.0
HFD1_k127_2596761_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 365.0
HFD1_k127_2596949_0 AcrB/AcrD/AcrF family K03296 - - 3.53e-314 993.0
HFD1_k127_2596949_1 Ami_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 319.0
HFD1_k127_2596949_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000001845 152.0
HFD1_k127_2596949_3 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000008769 139.0
HFD1_k127_2596949_4 PFAM outer membrane efflux protein - - - 0.00000000000000000000009547 109.0
HFD1_k127_2596949_5 peptidase U32 - - - 0.0000000000000003164 82.0
HFD1_k127_2597590_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 426.0
HFD1_k127_2597590_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 405.0
HFD1_k127_2597590_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 394.0
HFD1_k127_2600432_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 542.0
HFD1_k127_2600432_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000007167 181.0
HFD1_k127_2600432_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000001506 181.0
HFD1_k127_2600432_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000007323 76.0
HFD1_k127_2604851_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000001721 237.0
HFD1_k127_2604851_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000003093 235.0
HFD1_k127_2604851_2 - - - - 0.0000000000000000001799 94.0
HFD1_k127_2615141_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000001345 237.0
HFD1_k127_2615141_1 - - - - 0.00000000000000005871 88.0
HFD1_k127_2628127_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000000002004 132.0
HFD1_k127_2628127_1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768 - 2.7.1.202 0.0000000000000000000000000001759 120.0
HFD1_k127_2635020_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000002143 183.0
HFD1_k127_2635020_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000002059 143.0
HFD1_k127_2638817_0 Pfam:KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 392.0
HFD1_k127_2638817_1 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000001889 164.0
HFD1_k127_2638817_2 KaiB domain K08481 - - 0.0000000000000000000000000000008091 136.0
HFD1_k127_2641006_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1252.0
HFD1_k127_2641006_1 cation efflux system protein (Heavy metal efflux pump) - - - 0.0 1037.0
HFD1_k127_2641006_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000003354 122.0
HFD1_k127_264815_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000001016 151.0
HFD1_k127_264815_1 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.000000000000000000000009336 106.0
HFD1_k127_2652497_0 Tricorn protease homolog K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 396.0
HFD1_k127_2697646_0 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 403.0
HFD1_k127_2697646_1 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 321.0
HFD1_k127_2697646_2 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000003087 153.0
HFD1_k127_271389_0 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 324.0
HFD1_k127_271389_1 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008305 269.0
HFD1_k127_271389_2 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000001324 81.0
HFD1_k127_271389_3 Domain of unknown function (DUF4350) - - - 0.000000001812 70.0
HFD1_k127_271389_4 Domain of unknown function (DUF4129) - - - 0.00001612 55.0
HFD1_k127_2716270_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 611.0
HFD1_k127_2716270_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000003997 70.0
HFD1_k127_2723781_0 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 344.0
HFD1_k127_2723781_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000006462 68.0
HFD1_k127_2724139_0 Transposase IS66 family K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 366.0
HFD1_k127_2724139_1 Transposase and inactivated derivatives K07498 - - 0.000000000000000000000000000000000002707 140.0
HFD1_k127_2724139_2 Transposase IS66 family K07484 - - 0.000000000000000000000000000000000003511 145.0
HFD1_k127_2732575_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000004821 273.0
HFD1_k127_2732575_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000163 189.0
HFD1_k127_2732575_2 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000000000004558 188.0
HFD1_k127_2732575_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000003962 117.0
HFD1_k127_2732575_4 Biotin-requiring enzyme - - - 0.00000000000000000000000003776 119.0
HFD1_k127_2746406_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 357.0
HFD1_k127_2746406_1 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000004111 101.0
HFD1_k127_2747457_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 2.713e-290 898.0
HFD1_k127_2748730_0 radical SAM domain protein K22226 - - 0.00000000000000000000000000000000000000000000000000000000000000000003643 245.0
HFD1_k127_2752160_0 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 1.085e-244 773.0
HFD1_k127_2752160_1 pilus organization K07004 - - 0.00000000000000000000000000000000000002134 166.0
HFD1_k127_2752160_2 - - - - 0.00000000000000000000000000001068 128.0
HFD1_k127_2771570_0 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000001044 135.0
HFD1_k127_2778754_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 583.0
HFD1_k127_2779164_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000013 280.0
HFD1_k127_2780652_0 Peptidase dimerisation domain K01439,K13049 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 413.0
HFD1_k127_2780652_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000562 84.0
HFD1_k127_2782173_0 helicase activity K03578,K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001828 280.0
HFD1_k127_27852_0 COGs COG3415 Transposase and inactivated derivatives K07494 - - 0.00000000000000000000000000000000000000000000000000000000000003465 229.0
HFD1_k127_27852_1 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000002537 218.0
HFD1_k127_2789163_0 glutamate decarboxylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 578.0
HFD1_k127_2789163_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 315.0
HFD1_k127_2789163_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 317.0
HFD1_k127_2789163_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000009423 237.0
HFD1_k127_2789163_4 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000006602 208.0
HFD1_k127_2789163_5 Alpha beta hydrolase - - - 0.0000000000000000000000001848 119.0
HFD1_k127_2809280_0 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000001079 138.0
HFD1_k127_2809280_1 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.000000000000006045 76.0
HFD1_k127_2809280_2 chaperone-mediated protein folding - - - 0.0000005571 63.0
HFD1_k127_281651_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 335.0
HFD1_k127_281651_1 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000668 180.0
HFD1_k127_2827185_0 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 388.0
HFD1_k127_2827185_1 Transposase K07483 - - 0.0000000000000005769 79.0
HFD1_k127_2827185_2 Transposase K07483 - - 0.00001965 48.0
HFD1_k127_2831123_0 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 338.0
HFD1_k127_2831123_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000001346 177.0
HFD1_k127_2831123_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000006238 77.0
HFD1_k127_283438_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 465.0
HFD1_k127_283438_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000005108 160.0
HFD1_k127_2846961_0 Group II intron, maturase-specific domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 301.0
HFD1_k127_2846961_1 PFAM Transposase IS66 family K07484 - - 0.0000001587 55.0
HFD1_k127_2846961_2 PFAM Transposase, IS111A IS1328 IS1533, N-terminal - - - 0.0000006805 52.0
HFD1_k127_2849283_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 395.0
HFD1_k127_2849283_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000004318 235.0
HFD1_k127_2849283_2 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000006917 102.0
HFD1_k127_2849283_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0006493 49.0
HFD1_k127_287723_0 Cluster 0025 8 SCAB3371, SCAB4481, SCAB7601, SCAB11701, SCAB20281, SCAB40511, SCAB68181 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 475.0
HFD1_k127_287723_1 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000008283 72.0
HFD1_k127_287723_2 family acetyltransferase K03824 - - 0.000001003 53.0
HFD1_k127_2901132_0 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 468.0
HFD1_k127_2901132_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000001586 173.0
HFD1_k127_2911979_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 453.0
HFD1_k127_2918440_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404,K00405,K15862 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 602.0
HFD1_k127_2918440_1 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000006061 133.0
HFD1_k127_2918440_2 biogenesis protein K09792 - - 0.000000000000001866 89.0
HFD1_k127_2923881_0 Serine hydrolase (FSH1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 456.0
HFD1_k127_294421_0 Resolvase K06400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 342.0
HFD1_k127_294858_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004025 289.0
HFD1_k127_2949623_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000004188 222.0
HFD1_k127_2949623_1 Membrane - - - 0.0000000001126 69.0
HFD1_k127_2955879_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000005496 99.0
HFD1_k127_2955879_1 peptidyl-tyrosine sulfation - - - 0.00000000000000006612 96.0
HFD1_k127_2955879_2 domain, Protein - - - 0.00000000000000008889 93.0
HFD1_k127_296346_0 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000001482 82.0
HFD1_k127_2972162_0 PFAM transposase IS4 family protein - - - 3.904e-216 678.0
HFD1_k127_2972162_1 - - - - 0.000000000004456 70.0
HFD1_k127_3003881_0 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 522.0
HFD1_k127_3003881_1 protein conserved in bacteria - - - 0.0000000000000000000000001089 106.0
HFD1_k127_3007094_0 Alkaline phosphatase K01113 - 3.1.3.1 1.566e-227 720.0
HFD1_k127_3007094_1 endonuclease III - - - 0.0000000000000000000000005766 105.0
HFD1_k127_3007094_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000002507 98.0
HFD1_k127_3007094_3 Cyclic nucleotide-monophosphate binding domain K01420 - - 0.00001029 52.0
HFD1_k127_3016885_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 572.0
HFD1_k127_3016885_1 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000001473 156.0
HFD1_k127_3016921_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 579.0
HFD1_k127_3016921_1 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000006864 160.0
HFD1_k127_3021241_0 transposase activity K07493 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 419.0
HFD1_k127_3021241_1 PFAM transposase, IS4 family protein - - - 0.00000000000000000008763 90.0
HFD1_k127_3021241_2 integrase family - - - 0.00000001246 60.0
HFD1_k127_3028479_0 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 418.0
HFD1_k127_3045279_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 304.0
HFD1_k127_3045279_1 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000001246 132.0
HFD1_k127_3045279_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000001754 65.0
HFD1_k127_3045279_3 BlaR1 peptidase M56 - - - 0.000000006529 63.0
HFD1_k127_3050129_0 secondary active sulfate transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000788 259.0
HFD1_k127_3050129_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000005006 195.0
HFD1_k127_3065074_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000335 298.0
HFD1_k127_3065074_1 - - - - 0.00000000000000000000000000000000000000000000000000005651 194.0
HFD1_k127_307095_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 355.0
HFD1_k127_307095_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000005455 184.0
HFD1_k127_307095_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000001191 142.0
HFD1_k127_3086543_0 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 310.0
HFD1_k127_3086543_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001244 273.0
HFD1_k127_310184_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000971 207.0
HFD1_k127_310184_1 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000007523 181.0
HFD1_k127_310184_2 Cytochrome c - - - 0.000000000000000000000000002253 124.0
HFD1_k127_3113390_0 regulation of cell shape K04074,K07484 - - 0.0000000000000000000000000000000000133 146.0
HFD1_k127_3113390_1 AAA-like domain - - - 0.000000000000000000000000000000007905 129.0
HFD1_k127_311959_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000001332 201.0
HFD1_k127_311959_1 phosphoribosyltransferase K07100 - - 0.000000005146 66.0
HFD1_k127_311959_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000001791 50.0
HFD1_k127_3148109_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 316.0
HFD1_k127_3148109_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000002587 142.0
HFD1_k127_3148109_2 Glycosyl transferases group 1 - - - 0.0000000000364 67.0
HFD1_k127_3148109_3 lysyltransferase activity K07027 - - 0.00005459 55.0
HFD1_k127_3155858_0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000000000000002027 205.0
HFD1_k127_3155858_1 - - - - 0.0000000000000000003484 94.0
HFD1_k127_3159883_0 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000005871 126.0
HFD1_k127_3159883_1 peptidase K01415,K07386 - 3.4.24.71 0.000000000000000001567 85.0
HFD1_k127_3159883_2 amine dehydrogenase activity - - - 0.000000000000003327 82.0
HFD1_k127_31626_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 447.0
HFD1_k127_31626_2 Small integral membrane protein 24 - - - 0.000607 47.0
HFD1_k127_3175244_0 DinB family - - - 0.00000000000000000000000000001322 131.0
HFD1_k127_3175244_1 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000008543 114.0
HFD1_k127_3175244_2 Dehydrogenase - - - 0.00000000000000000000002295 100.0
HFD1_k127_3203488_0 Lysin motif K08307 - - 0.0000000000000000000000000000000000000004098 160.0
HFD1_k127_3217889_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 404.0
HFD1_k127_3217889_1 PFAM LemA family K03744 - - 0.00000000000000000000000003736 110.0
HFD1_k127_3218063_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 318.0
HFD1_k127_3218063_1 - - - - 0.000000000000000000001089 100.0
HFD1_k127_3218063_2 Homeodomain-like domain - - - 0.00000000000003214 81.0
HFD1_k127_3218063_3 unidirectional conjugation - - - 0.000003847 53.0
HFD1_k127_3218543_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001426 266.0
HFD1_k127_3218543_1 Transcriptional Regulator, AraC family - - - 0.000000000000000000000000000000000000000000000002943 183.0
HFD1_k127_3218543_2 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.0000000000000000000005373 106.0
HFD1_k127_3218543_3 Protein of unknown function (DUF3761) - - - 0.0000000000000000006842 92.0
HFD1_k127_3218543_4 MacB-like periplasmic core domain - - - 0.000001617 57.0
HFD1_k127_321906_0 Peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000009786 211.0
HFD1_k127_321906_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000004639 188.0
HFD1_k127_321906_2 peptidyl-tyrosine sulfation - - - 0.0000001163 55.0
HFD1_k127_3229702_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008234 259.0
HFD1_k127_3229702_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000001953 163.0
HFD1_k127_3229702_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.00000000000000000000000003155 125.0
HFD1_k127_3230051_0 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 394.0
HFD1_k127_3230051_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000001056 108.0
HFD1_k127_3230051_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000002552 60.0
HFD1_k127_3230985_0 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003414 243.0
HFD1_k127_3230985_1 OmpA family K03286 - - 0.000000009908 63.0
HFD1_k127_3233663_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 432.0
HFD1_k127_3233663_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 324.0
HFD1_k127_3240984_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 479.0
HFD1_k127_3240984_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 359.0
HFD1_k127_3240984_2 Alpha/beta hydrolase family - - - 0.000000000000006788 85.0
HFD1_k127_3240984_3 oxidoreductase - - - 0.00000002203 57.0
HFD1_k127_3243559_0 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 458.0
HFD1_k127_3243559_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 353.0
HFD1_k127_3243559_2 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 302.0
HFD1_k127_3243559_3 - - - - 0.0000000000000000001332 96.0
HFD1_k127_3243559_4 Regulatory protein, FmdB family - - - 0.000002725 49.0
HFD1_k127_3246488_0 efflux transmembrane transporter activity - - - 1.763e-200 660.0
HFD1_k127_3246488_1 TonB dependent receptor K16089 - - 0.000000000000000000000000000000000000000000000000000000000000000007644 242.0
HFD1_k127_3246488_2 tRNA wobble cytosine modification - - - 0.0000000000000000000000000000000000000000000000000000000008195 213.0
HFD1_k127_3246488_3 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000000002795 179.0
HFD1_k127_3246488_4 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000001386 128.0
HFD1_k127_3246488_5 sulfuric ester hydrolase activity - - - 0.000000000000001269 82.0
HFD1_k127_3246713_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 374.0
HFD1_k127_3246713_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000001645 192.0
HFD1_k127_3246713_2 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.0000000000000000000000000002043 121.0
HFD1_k127_3246713_3 Domain of unknown function (DUF4382) - - - 0.0000000000007352 81.0
HFD1_k127_3247747_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 300.0
HFD1_k127_3254066_0 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000000193 186.0
HFD1_k127_3254066_1 Penicillinase repressor - - - 0.0000000000000000000000000000000003545 134.0
HFD1_k127_3256373_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 402.0
HFD1_k127_3256373_1 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000007648 174.0
HFD1_k127_3258155_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 1.004e-250 788.0
HFD1_k127_3258155_1 Peptidase family M28 - - - 2.973e-196 655.0
HFD1_k127_3258155_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 522.0
HFD1_k127_3258155_3 aminopeptidase activity - - - 0.00000000000000000000000000002601 125.0
HFD1_k127_3261217_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 301.0
HFD1_k127_3261217_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000001417 164.0
HFD1_k127_3264536_0 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 550.0
HFD1_k127_3264536_1 PFAM Na dependent nucleoside transporter K03317 - - 0.00000007152 59.0
HFD1_k127_3269730_0 PPIC-type PPIASE domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001406 233.0
HFD1_k127_3275622_0 PFAM transposase IS66 K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 374.0
HFD1_k127_3275622_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07484 - - 0.00000000000000000000000000000000000000000001471 167.0
HFD1_k127_3275622_2 zinc-finger binding domain of transposase IS66 - - - 0.00000000000000000000000000000000001324 143.0
HFD1_k127_3275622_3 transposase activity - - - 0.0000000000000000008615 86.0
HFD1_k127_3275622_4 Transposase K07483 - - 0.0000000000008347 74.0
HFD1_k127_327718_0 Bacterial low temperature requirement A protein (LtrA) - - - 0.0000000000000000000000000000000000000000000000000000000000005547 218.0
HFD1_k127_327718_1 dehydrogenase complex catalyzes the overall conversion of - - - 0.00000000000000000007842 97.0
HFD1_k127_328118_0 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 464.0
HFD1_k127_328118_1 Thioredoxin - - - 0.0000000000000002588 81.0
HFD1_k127_328118_2 Transcriptional regulator K22106 - - 0.000000000003297 74.0
HFD1_k127_328118_3 Peptidase family S41 K03797 - 3.4.21.102 0.000004442 53.0
HFD1_k127_3281823_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003961 267.0
HFD1_k127_3281823_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000416 148.0
HFD1_k127_3283242_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 349.0
HFD1_k127_3283242_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000001271 243.0
HFD1_k127_3283242_2 PFAM Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000001441 185.0
HFD1_k127_3283242_3 ECF sigma factor K03088 - - 0.000000000000000000000000000007207 126.0
HFD1_k127_3284848_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 296.0
HFD1_k127_3284848_1 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005726 266.0
HFD1_k127_3284848_2 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000003887 213.0
HFD1_k127_3284848_3 Transposase DDE domain - - - 0.00000000000000000000000003857 111.0
HFD1_k127_3284848_4 Transposase and inactivated derivatives - - - 0.00000000000000000000008492 100.0
HFD1_k127_3284848_5 Transposase DDE domain - - - 0.00005135 49.0
HFD1_k127_3289753_0 Atp-dependent helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 597.0
HFD1_k127_3289753_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 467.0
HFD1_k127_3289753_2 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000001096 101.0
HFD1_k127_3289753_3 Rdx family K07401 - - 0.0000000001802 63.0
HFD1_k127_3292411_0 Peptidase family M1 domain K01256 - 3.4.11.2 0.000000000000000000000000000000000000000002268 176.0
HFD1_k127_3292411_1 4 iron, 4 sulfur cluster binding K02572,K02573 - - 0.00000000000000000009281 95.0
HFD1_k127_3299092_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 427.0
HFD1_k127_3299092_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000002218 171.0
HFD1_k127_3299092_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000122 127.0
HFD1_k127_3308107_0 DNA ligase (ATP) activity K01971 - 6.5.1.1 7.937e-244 769.0
HFD1_k127_3308361_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 546.0
HFD1_k127_3308361_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 458.0
HFD1_k127_3308361_2 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000006726 258.0
HFD1_k127_3308361_3 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000008125 209.0
HFD1_k127_3308361_4 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000004414 131.0
HFD1_k127_3308361_5 - - - - 0.00000000000000002472 95.0
HFD1_k127_3310151_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 326.0
HFD1_k127_3310151_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000001494 249.0
HFD1_k127_3310151_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000001636 263.0
HFD1_k127_3316599_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 8.076e-224 717.0
HFD1_k127_3316599_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001506 266.0
HFD1_k127_3321024_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.0000000000000000000000128 105.0
HFD1_k127_3321024_1 Transposase IS116/IS110/IS902 family - - - 0.000000001451 66.0
HFD1_k127_3321024_2 Transposase - - - 0.000001797 60.0
HFD1_k127_3328416_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 464.0
HFD1_k127_3339361_0 2-oxoglutarate dehydrogenase C-terminal K00164 - 1.2.4.2 0.0 1114.0
HFD1_k127_3339361_1 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 345.0
HFD1_k127_3339361_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000006659 250.0
HFD1_k127_3339361_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000001515 186.0
HFD1_k127_3339361_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000376 169.0
HFD1_k127_3339361_5 YGGT family K02221 - - 0.00000000000000000000000000000004624 132.0
HFD1_k127_3339361_6 Belongs to the UPF0235 family K09131 - - 0.0000000000000000005921 90.0
HFD1_k127_3341490_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000002786 232.0
HFD1_k127_3341490_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000004765 206.0
HFD1_k127_3341490_2 DDE superfamily endonuclease - - - 0.0000000000000000000001099 101.0
HFD1_k127_3341490_3 DDE superfamily endonuclease - - - 0.0000000000000000001179 91.0
HFD1_k127_3341490_4 PFAM Transposase DDE domain - - - 0.000000000000000006168 83.0
HFD1_k127_3341490_5 PFAM Integrase catalytic K07497 - - 0.0000009448 51.0
HFD1_k127_3350101_0 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 466.0
HFD1_k127_3350101_1 Phage integrase family K03733 - - 0.00000008262 57.0
HFD1_k127_3351399_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 456.0
HFD1_k127_3351399_1 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 384.0
HFD1_k127_3354525_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 294.0
HFD1_k127_3354525_1 transmembrane transporter activity K13021 - - 0.000000000000000000000000000000000000000234 155.0
HFD1_k127_3355895_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000001435 203.0
HFD1_k127_3355895_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000002743 186.0
HFD1_k127_3355895_2 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000002284 162.0
HFD1_k127_3356468_0 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000007047 160.0
HFD1_k127_3356468_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18306 - - 0.0000000000000000000000000000000000002605 162.0
HFD1_k127_3356468_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.0000000000000000000000000004069 116.0
HFD1_k127_3358281_0 Large extracellular alpha-helical protein K06894 - - 3.799e-299 941.0
HFD1_k127_3358281_1 Amidohydrolase family - - - 0.00000000000000000000000000000179 132.0
HFD1_k127_3359016_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000002536 90.0
HFD1_k127_3361133_0 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000001168 161.0
HFD1_k127_3361133_1 methyltransferase activity - - - 0.00000000000001473 87.0
HFD1_k127_3365548_0 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 374.0
HFD1_k127_3368053_0 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 582.0
HFD1_k127_3368053_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 569.0
HFD1_k127_3368053_2 zinc-finger binding domain of transposase IS66 - - - 0.000000002251 59.0
HFD1_k127_3368053_3 Transposase - - - 0.000007298 50.0
HFD1_k127_3371303_0 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 354.0
HFD1_k127_3371303_1 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000009347 132.0
HFD1_k127_3376641_0 Transposase DDE domain group 1 - - - 5.718e-195 618.0
HFD1_k127_3376641_1 Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000114 56.0
HFD1_k127_3376790_0 Prolyl oligopeptidase family K01303 - 3.4.19.1 1.335e-273 858.0
HFD1_k127_3376790_1 Acyl-CoA synthetase (NDP forming) K01905,K18594,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000001909 190.0
HFD1_k127_3376790_2 DinB superfamily - - - 0.00000000000000000000000000000000000007217 155.0
HFD1_k127_3382074_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000005081 226.0
HFD1_k127_3384186_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 623.0
HFD1_k127_3384186_1 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000001035 179.0
HFD1_k127_3384186_2 elongation factor G K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 0.000000000000000000000000000005283 121.0
HFD1_k127_3384194_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 562.0
HFD1_k127_3387810_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000004468 216.0
HFD1_k127_3387810_1 domain protein K13735,K20276 - - 0.00000000008993 74.0
HFD1_k127_3388333_0 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000153 276.0
HFD1_k127_3388333_1 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000007238 243.0
HFD1_k127_3388333_2 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000006333 194.0
HFD1_k127_3393300_0 BNR Asp-box repeat - - - 0.00000000000000000000004446 102.0
HFD1_k127_3401933_0 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 325.0
HFD1_k127_3401933_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 284.0
HFD1_k127_3401933_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000004241 193.0
HFD1_k127_3401933_3 Citrate transporter - - - 0.000000000000000000000000000000007095 132.0
HFD1_k127_3401933_4 Cupin domain - - - 0.00000000000001797 77.0
HFD1_k127_340368_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 328.0
HFD1_k127_340368_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000001156 213.0
HFD1_k127_340368_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000005363 201.0
HFD1_k127_3408934_0 GTPase activity K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 605.0
HFD1_k127_3408934_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 400.0
HFD1_k127_3408934_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000002138 248.0
HFD1_k127_3413049_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 325.0
HFD1_k127_3413049_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000007158 101.0
HFD1_k127_3414417_0 AAA domain K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 569.0
HFD1_k127_3414417_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 342.0
HFD1_k127_3414417_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 327.0
HFD1_k127_3414417_3 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 303.0
HFD1_k127_3416101_0 O-acyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004882 263.0
HFD1_k127_3416101_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005893 256.0
HFD1_k127_3416101_2 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.00000000000000000000134 105.0
HFD1_k127_3416101_3 PFAM CBS domain containing protein - - - 0.00000000000001051 79.0
HFD1_k127_3416101_4 Belongs to the universal stress protein A family - - - 0.000000000004296 77.0
HFD1_k127_3416101_5 PFAM CBS domain containing protein K07182 - - 0.00000000213 68.0
HFD1_k127_3416101_6 Universal stress protein family - - - 0.00001406 56.0
HFD1_k127_342277_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 332.0
HFD1_k127_342277_1 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000638 127.0
HFD1_k127_342277_2 - - - - 0.000000000001025 70.0
HFD1_k127_3425377_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000001544 88.0
HFD1_k127_3425377_1 Tetratricopeptide repeat - - - 0.00000000000302 68.0
HFD1_k127_3429536_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000002 201.0
HFD1_k127_3429536_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000002587 140.0
HFD1_k127_3430111_0 Transposase C of IS166 homeodomain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 383.0
HFD1_k127_3430111_1 COG3436 Transposase and inactivated derivatives K07484 - - 0.00000000000000000000000000000000000000001837 154.0
HFD1_k127_3430111_2 zinc-finger binding domain of transposase IS66 K07484 - - 0.0000000000000000000000000000000004545 139.0
HFD1_k127_3430111_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000517 64.0
HFD1_k127_3434639_0 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 300.0
HFD1_k127_3434639_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000003582 94.0
HFD1_k127_3437929_0 RDD family K06384 - - 0.000000000000000000000000000000000000000000000000000000000000000004123 243.0
HFD1_k127_3437929_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000002325 193.0
HFD1_k127_3438611_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 544.0
HFD1_k127_3438611_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000002746 194.0
HFD1_k127_3438611_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.0000000000000001787 80.0
HFD1_k127_3441187_0 Heat shock protein HtpX K03799 - - 0.000000000000000000000000000000000000000000000001566 187.0
HFD1_k127_3442559_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000004465 203.0
HFD1_k127_3442559_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000009915 157.0
HFD1_k127_3451156_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 576.0
HFD1_k127_3451827_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 439.0
HFD1_k127_3451827_1 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000005146 258.0
HFD1_k127_3456746_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000002498 207.0
HFD1_k127_3456746_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000298 169.0
HFD1_k127_345744_0 Transposase, mutator - - - 0.000000000000000000000000000000000000000000000000000000000005818 218.0
HFD1_k127_345744_1 Transposase, mutator - - - 0.0000000000000000000000000000000000000006546 150.0
HFD1_k127_345744_2 Transposase, mutator - - - 0.000000000000000000000000000000000003037 145.0
HFD1_k127_345744_3 Transposase, mutator - - - 0.0000000000004431 70.0
HFD1_k127_345744_4 Transposase - - - 0.0001393 44.0
HFD1_k127_3457679_0 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 403.0
HFD1_k127_3463526_0 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 434.0
HFD1_k127_3467848_0 - - - - 0.0000000000000000000000000000000000000000000000001357 190.0
HFD1_k127_3475152_0 transposase activity - - - 0.00000000000000000000000000000000000003714 148.0
HFD1_k127_3475152_1 Evidence 2b Function of strongly homologous gene K07497 - - 0.0000000000000000000000000000003028 128.0
HFD1_k127_3475152_2 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.0000000000001102 75.0
HFD1_k127_347964_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 405.0
HFD1_k127_347964_1 Cell division protein FtsQ K03589 - - 0.0000000000299 68.0
HFD1_k127_3479916_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 425.0
HFD1_k127_3479916_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 362.0
HFD1_k127_3479916_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000001337 202.0
HFD1_k127_3479916_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000001105 201.0
HFD1_k127_3479916_4 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.000000000000000000000000000000000001165 146.0
HFD1_k127_3479916_5 - - - - 0.00000003331 66.0
HFD1_k127_3485824_0 PFAM Integrase, catalytic core - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 445.0
HFD1_k127_3485824_1 Polysaccharide pyruvyl transferase - - - 0.000000000000001515 78.0
HFD1_k127_3485824_2 phosphatase - - - 0.0000000000003313 73.0
HFD1_k127_3485824_3 Evidence 2b Function of strongly homologous gene - - - 0.00001235 55.0
HFD1_k127_3488512_0 Transposase K07483 - - 0.0000000000000000000000000000000000005769 141.0
HFD1_k127_3488512_1 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000009939 139.0
HFD1_k127_3488512_2 PFAM Integrase catalytic K07497 - - 0.00000000000000000000000000000002787 130.0
HFD1_k127_3500497_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 511.0
HFD1_k127_3500497_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000001146 126.0
HFD1_k127_3500497_2 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000006846 100.0
HFD1_k127_3506149_0 Ig domain protein group 1 domain protein - - - 0.000000000000003084 86.0
HFD1_k127_3506149_1 Peptidase M1, membrane alanine aminopeptidase - - - 0.00001783 57.0
HFD1_k127_3529940_0 rna polymerase sigma factor K03090 - - 0.000000000000000000000000000000000000001811 154.0
HFD1_k127_3530965_0 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007116 255.0
HFD1_k127_3530965_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002079 249.0
HFD1_k127_3530965_2 PAS PAC sensor signal transduction histidine kinase - - - 0.0000000000000000000000005287 120.0
HFD1_k127_3531386_0 metallocarboxypeptidase activity K14054 - - 1.991e-194 618.0
HFD1_k127_3531386_1 PFAM aldo keto reductase K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000563 263.0
HFD1_k127_3533323_0 dihydroorotate dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000009409 241.0
HFD1_k127_3533323_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000009073 61.0
HFD1_k127_3535850_0 Sigma-70, region 4 K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000004429 220.0
HFD1_k127_3535850_1 PFAM Pentapeptide - - - 0.0000000000000000001292 100.0
HFD1_k127_3537101_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001444 254.0
HFD1_k127_3537101_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000004773 76.0
HFD1_k127_3547117_0 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 533.0
HFD1_k127_3555009_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 470.0
HFD1_k127_3555009_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 345.0
HFD1_k127_3558515_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 302.0
HFD1_k127_3558515_1 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000000000000000000000000000000000002435 209.0
HFD1_k127_3558515_2 - - - - 0.000000000000000000000000000000000000000000004529 171.0
HFD1_k127_3558515_3 Domain of unknown function (DUF309) K09763 - - 0.00000000004076 68.0
HFD1_k127_3569307_0 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000002047 205.0
HFD1_k127_3569307_1 4-vinyl reductase, 4VR - - - 0.0000000000000025 83.0
HFD1_k127_3573387_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000008877 115.0
HFD1_k127_3573387_1 3-hydroxyacyl-CoA dehydrogenase activity - - - 0.0000000000000463 80.0
HFD1_k127_3575975_0 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 273.0
HFD1_k127_3575975_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000002136 130.0
HFD1_k127_3580352_0 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 496.0
HFD1_k127_3580600_0 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000001364 150.0
HFD1_k127_3580600_1 Protein of unknown function (DUF1343) - - - 0.000000000000000000000001933 107.0
HFD1_k127_3582475_0 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 519.0
HFD1_k127_3582475_1 PAS domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000001361 171.0
HFD1_k127_3582475_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000239 67.0
HFD1_k127_3595500_0 PglZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 502.0
HFD1_k127_3595500_1 DnaB-like helicase C terminal domain K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000378 200.0
HFD1_k127_3595500_2 PFAM glycosyl transferase family 9 K02843 - - 0.0000000000000000000000000000000000000000000000000000238 200.0
HFD1_k127_3598458_0 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 348.0
HFD1_k127_3598458_1 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000006117 137.0
HFD1_k127_3598458_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000002622 121.0
HFD1_k127_3598458_3 Iron permease FTR1 family K07243 - - 0.000000303 57.0
HFD1_k127_3598458_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.000001268 61.0
HFD1_k127_3598458_5 PFAM cytochrome - - - 0.00005329 50.0
HFD1_k127_3601172_0 Phosphoesterase family K21302 - 3.1.3.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 304.0
HFD1_k127_3601172_1 Domain of unknown function (DUF5117) - - - 0.000000000000000000000000000000000000000000000000000000000000000009674 234.0
HFD1_k127_3601172_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000005482 191.0
HFD1_k127_3601617_0 PFAM Transposase, IS204 IS1001 IS1096 IS1165 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 392.0
HFD1_k127_3601617_1 transposase activity - - - 0.00001949 49.0
HFD1_k127_3601617_3 N-terminal domain of reverse transcriptase K00986 - 2.7.7.49 0.0002427 46.0
HFD1_k127_3601665_0 Polysaccharide biosynthesis protein K01710,K15894,K15912,K19421 GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 4.2.1.115,4.2.1.135,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 592.0
HFD1_k127_3601665_1 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000007132 164.0
HFD1_k127_3604806_0 Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000835 219.0
HFD1_k127_3604806_1 TRAP-type C4-dicarboxylate transport system, small permease component K11689 - - 0.00000136 50.0
HFD1_k127_3610840_0 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 357.0
HFD1_k127_3610840_1 beta' subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000008568 166.0
HFD1_k127_3620165_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000003219 148.0
HFD1_k127_3620165_1 Winged helix-turn helix - - - 0.00000000000000000000000000000000000005721 148.0
HFD1_k127_363286_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 541.0
HFD1_k127_363286_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 450.0
HFD1_k127_3636382_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 553.0
HFD1_k127_3636382_1 PFAM Integrase catalytic - - - 0.0000000000000000000000002091 109.0
HFD1_k127_3636382_2 IS66 Orf2 like protein K07484 - - 0.0000001465 53.0
HFD1_k127_3636382_3 IS66 Orf2 like protein K07484 - - 0.00001268 56.0
HFD1_k127_3636547_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 433.0
HFD1_k127_3636547_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 316.0
HFD1_k127_3636547_2 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000000000000000000000000001168 148.0
HFD1_k127_3636547_3 - - - - 0.000000005663 66.0
HFD1_k127_3640589_0 HEAT repeats - - - 0.0000001969 63.0
HFD1_k127_3640589_1 deoxyhypusine monooxygenase activity - - - 0.0001612 54.0
HFD1_k127_3653489_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000152 177.0
HFD1_k127_3653489_1 DinB superfamily - - - 0.0000000000000000000003361 104.0
HFD1_k127_3654821_0 DDE superfamily endonuclease K07494 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 326.0
HFD1_k127_3654821_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000005081 117.0
HFD1_k127_3654821_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000005728 121.0
HFD1_k127_3690364_0 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000002813 227.0
HFD1_k127_3690364_1 Predicted membrane protein (DUF2231) - - - 0.000000000000004549 83.0
HFD1_k127_3690364_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000008684 56.0
HFD1_k127_369904_0 thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate K01130 GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509 3.1.6.1 0.0 1466.0
HFD1_k127_369904_1 radical SAM K06871 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 - 1.354e-218 688.0
HFD1_k127_369904_2 - - - - 0.0000000000000000000000000000000000000000541 157.0
HFD1_k127_369904_3 UPF0126 domain - - - 0.000000000000000000000000004529 115.0
HFD1_k127_3700197_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000052 168.0
HFD1_k127_3708643_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006615 246.0
HFD1_k127_3708643_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000003446 104.0
HFD1_k127_371687_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.867e-296 918.0
HFD1_k127_371687_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000007044 206.0
HFD1_k127_371687_2 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000002838 196.0
HFD1_k127_3732526_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 612.0
HFD1_k127_3732526_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 362.0
HFD1_k127_3732526_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000007966 124.0
HFD1_k127_3732526_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000002999 63.0
HFD1_k127_376626_0 Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000001126 246.0
HFD1_k127_376723_0 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 311.0
HFD1_k127_376723_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000003709 111.0
HFD1_k127_3782354_0 Transposase DDE domain group 1 - - - 1.472e-227 712.0
HFD1_k127_3782354_1 - - - - 0.000000000000000000000000000000552 141.0
HFD1_k127_3782354_2 Psort location Cytoplasmic, score - - - 0.000000000001511 75.0
HFD1_k127_3807978_0 - - - - 0.000000000000000000000000000000001801 132.0
HFD1_k127_3807978_1 - - - - 0.00000000000000000000000002757 118.0
HFD1_k127_3814839_0 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000002505 141.0
HFD1_k127_382147_0 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 344.0
HFD1_k127_382147_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000003556 201.0
HFD1_k127_382147_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000002149 135.0
HFD1_k127_382147_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000002075 88.0
HFD1_k127_3822247_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007819 260.0
HFD1_k127_3822247_1 HAD-superfamily subfamily IB hydrolase, TIGR01490 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000001188 179.0
HFD1_k127_3822247_2 Integrase core domain - - - 0.00000000000000000000000000000000881 139.0
HFD1_k127_3822247_3 required for the transposition of insertion element IS2404 - - - 0.0005555 44.0
HFD1_k127_3837164_0 - - - - 0.000000000000000000000000000000000000007209 151.0
HFD1_k127_3837164_1 - - - - 0.00000000000000000000000000000000004514 144.0
HFD1_k127_3845028_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 529.0
HFD1_k127_3845028_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 472.0
HFD1_k127_3845028_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 405.0
HFD1_k127_3845028_3 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 338.0
HFD1_k127_3845028_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 300.0
HFD1_k127_3845028_5 Universal stress protein family - - - 0.000000003648 64.0
HFD1_k127_3852020_0 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 358.0
HFD1_k127_3852020_1 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000001286 177.0
HFD1_k127_3856161_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 406.0
HFD1_k127_3856161_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003017 274.0
HFD1_k127_3856161_2 Hydrogenase 4 membrane - - - 0.00000000000000000001973 91.0
HFD1_k127_3859983_0 Patatin-like phospholipase - - - 0.000000000000000000000000003876 127.0
HFD1_k127_3863833_0 Transposase - - - 0.00000000000000000000000000000000006158 135.0
HFD1_k127_3863833_1 membrane - - - 0.00000000000000000000006918 102.0
HFD1_k127_3863833_2 Transposase - - - 0.000000000000000002635 85.0
HFD1_k127_3884965_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 338.0
HFD1_k127_3884965_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 330.0
HFD1_k127_3884965_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003662 283.0
HFD1_k127_3884965_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000111 204.0
HFD1_k127_3884965_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000001781 177.0
HFD1_k127_3884965_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000005344 149.0
HFD1_k127_3884965_6 Ribosomal protein L33 K02913 - - 0.000000000000000004666 84.0
HFD1_k127_3884965_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000005122 53.0
HFD1_k127_3885528_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 582.0
HFD1_k127_3885528_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003438 279.0
HFD1_k127_3888802_0 PFAM Integrase, catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000001933 237.0
HFD1_k127_3888802_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000001073 85.0
HFD1_k127_3888802_2 PFAM transposase IS3 IS911 family protein - - - 0.0000000000000005323 81.0
HFD1_k127_3888802_3 Integrase core domain - - - 0.0000000005468 67.0
HFD1_k127_3919323_0 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 461.0
HFD1_k127_3919323_1 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001192 259.0
HFD1_k127_3976839_0 Transposase IS116/IS110/IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 464.0
HFD1_k127_3977761_0 - - - - 0.000000000000000000000000000000008646 134.0
HFD1_k127_3977761_1 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000004314 67.0
HFD1_k127_3983164_0 Protein of unknown function (DUF664) - - - 0.00000000000000000002267 94.0
HFD1_k127_4025235_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000001328 230.0
HFD1_k127_4027047_0 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001509 271.0
HFD1_k127_4027047_1 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000003493 205.0
HFD1_k127_4027047_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P) K07094 - - 0.000000000000000000000000002089 115.0
HFD1_k127_4027047_3 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000002507 94.0
HFD1_k127_4028388_0 Transposase K07493 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 474.0
HFD1_k127_4028388_1 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000001716 100.0
HFD1_k127_4028388_2 - - - - 0.00000000000000000001761 95.0
HFD1_k127_4031395_0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 546.0
HFD1_k127_4036031_0 Aldo/keto reductase family K06607 - - 0.0000000000000000000000000000000000000000000000000002117 199.0
HFD1_k127_4036302_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002581 283.0
HFD1_k127_4036302_1 COG0840 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000002498 224.0
HFD1_k127_4036302_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.00000001197 58.0
HFD1_k127_4037438_0 major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 492.0
HFD1_k127_4037438_1 Zincin-like metallopeptidase - - - 0.0000000000000001068 89.0
HFD1_k127_4037438_2 Domain of unknown function (DUF4404) - - - 0.0000002864 63.0
HFD1_k127_403798_0 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000002357 215.0
HFD1_k127_403798_1 UvrB/uvrC motif K19411 - - 0.0000000000000000000000000000000000009226 143.0
HFD1_k127_4039726_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.586e-220 702.0
HFD1_k127_4039726_1 - K00241 - - 0.000000000000000000000000000000000000000000000000000000001074 208.0
HFD1_k127_4043719_0 required for the transposition of insertion element IS2404 - - - 0.00000000000000000000000000000000000000000000004086 179.0
HFD1_k127_4043719_1 required for the transposition of insertion element IS2404 - - - 0.000000000000000000000000002178 126.0
HFD1_k127_4043719_2 required for the transposition of insertion element IS2404 - - - 0.0000000000000000008529 92.0
HFD1_k127_4043719_3 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000005811 68.0
HFD1_k127_4046140_0 COG5659 FOG Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 370.0
HFD1_k127_4046140_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000002464 229.0
HFD1_k127_4046808_0 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005151 242.0
HFD1_k127_4046808_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000002073 224.0
HFD1_k127_4046808_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000003988 213.0
HFD1_k127_4046808_3 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000002672 158.0
HFD1_k127_4054678_0 iron-regulated membrane protein K03863 - - 0.000000000000000000000000000000000000000000000000000000000009829 223.0
HFD1_k127_4054678_1 luxR family - - - 0.00000000000000000000000000000000003186 141.0
HFD1_k127_4054678_2 - - - - 0.0000000001375 63.0
HFD1_k127_4055646_0 - - - - 0.000000000001157 79.0
HFD1_k127_4057054_0 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004979 267.0
HFD1_k127_4057054_1 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000001008 68.0
HFD1_k127_4057054_2 Cbs domain - - - 0.0000003937 58.0
HFD1_k127_4057987_0 lysine biosynthetic process via aminoadipic acid - - - 5.131e-236 754.0
HFD1_k127_4057987_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 322.0
HFD1_k127_4057987_3 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000004582 229.0
HFD1_k127_4057987_4 glyoxalase III activity - - - 0.00000001004 57.0
HFD1_k127_4061801_0 PFAM Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 422.0
HFD1_k127_4061801_1 Maf-like protein K06287 - - 0.000000000000000000000000000000000002944 138.0
HFD1_k127_4065222_0 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 576.0
HFD1_k127_4065222_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 504.0
HFD1_k127_4065222_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000005072 133.0
HFD1_k127_4065222_3 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.0000000000003606 74.0
HFD1_k127_4068463_0 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001876 261.0
HFD1_k127_4068463_1 - - - - 0.000000000000000002464 92.0
HFD1_k127_4073046_0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000002314 192.0
HFD1_k127_4073046_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0008741 42.0
HFD1_k127_4073712_0 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001947 246.0
HFD1_k127_4073712_1 - - - - 0.0000000000000000000000000000000000000000000000000003798 196.0
HFD1_k127_4073712_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000009122 158.0
HFD1_k127_4073712_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000719 129.0
HFD1_k127_4073757_0 Large extracellular alpha-helical protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 422.0
HFD1_k127_4079628_0 PFAM peptidase M18 aminopeptidase I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 426.0
HFD1_k127_4079628_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000009403 180.0
HFD1_k127_4079710_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 334.0
HFD1_k127_4085012_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 450.0
HFD1_k127_4085012_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000004448 226.0
HFD1_k127_4085012_2 Transposase K07483 - - 0.0000000000000000000000000000001698 128.0
HFD1_k127_4087367_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 406.0
HFD1_k127_4087367_1 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 373.0
HFD1_k127_4087367_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005514 262.0
HFD1_k127_4087367_3 Protein of unknown function (DUF1706) - - - 0.000000000000000000000000000000000000000000000000000007493 194.0
HFD1_k127_4087367_4 - - - - 0.000001416 52.0
HFD1_k127_4090460_0 Cellulose biosynthesis protein BcsQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000002444 241.0
HFD1_k127_4090460_1 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000000000000001014 223.0
HFD1_k127_4090460_2 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000001465 220.0
HFD1_k127_4090460_3 Transposase - - - 0.000000000000000000000000000000000804 137.0
HFD1_k127_4090460_4 - - - - 0.00000000000000000000000000001365 120.0
HFD1_k127_4090460_5 Transposase K07492 - - 0.0000000000000000000001987 98.0
HFD1_k127_4090460_6 Transposase - - - 0.0000000000000000003652 91.0
HFD1_k127_4090629_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006065 267.0
HFD1_k127_4090629_1 ABC transporter, ATP-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000312 256.0
HFD1_k127_4090629_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000002424 117.0
HFD1_k127_4090629_3 MlaD protein K02067 - - 0.000000000000000006384 89.0
HFD1_k127_4097982_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 462.0
HFD1_k127_4097982_1 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000001507 151.0
HFD1_k127_4097982_2 Group II intron, maturase-specific domain - - - 0.000000000000000000000000011 111.0
HFD1_k127_4097982_3 - - - - 0.0000005968 56.0
HFD1_k127_4098582_0 PFAM regulatory protein LuxR - - - 0.0004889 52.0
HFD1_k127_4102397_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 417.0
HFD1_k127_4102397_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000004175 64.0
HFD1_k127_4105698_0 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000001651 178.0
HFD1_k127_4105698_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000003708 119.0
HFD1_k127_4105698_2 Transposase DDE domain group 1 - - - 0.00000000000000001698 81.0
HFD1_k127_4107841_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000165 160.0
HFD1_k127_4108288_0 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 364.0
HFD1_k127_4108680_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 570.0
HFD1_k127_4108680_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 417.0
HFD1_k127_4108680_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 329.0
HFD1_k127_4108680_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000007999 110.0
HFD1_k127_4108680_4 Ribosomal protein L34 K02914 - - 0.00000000000000003571 89.0
HFD1_k127_4108680_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.000001851 55.0
HFD1_k127_4112217_0 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 386.0
HFD1_k127_4112217_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 321.0
HFD1_k127_4112217_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000003879 216.0
HFD1_k127_4112217_3 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000006488 168.0
HFD1_k127_4114654_0 Involved in initiation control of chromosome replication K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 387.0
HFD1_k127_4114654_1 CHAT domain - - - 0.00006446 47.0
HFD1_k127_4115126_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 302.0
HFD1_k127_4115126_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007774 291.0
HFD1_k127_4115396_0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000004255 230.0
HFD1_k127_4115396_1 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000003343 157.0
HFD1_k127_4115396_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000003634 82.0
HFD1_k127_4115396_3 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000001937 55.0
HFD1_k127_4116232_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1073.0
HFD1_k127_4116232_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.622e-255 803.0
HFD1_k127_4116232_10 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000009988 111.0
HFD1_k127_4116232_11 TilS substrate C-terminal domain K04075,K15780 - 2.4.2.8,6.3.4.19 0.000000000003127 77.0
HFD1_k127_4116232_12 cheY-homologous receiver domain K03413 - - 0.00000000007268 62.0
HFD1_k127_4116232_13 CheW-like domain - - - 0.0001203 51.0
HFD1_k127_4116232_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 339.0
HFD1_k127_4116232_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007572 272.0
HFD1_k127_4116232_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001233 287.0
HFD1_k127_4116232_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000005543 264.0
HFD1_k127_4116232_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000001621 244.0
HFD1_k127_4116232_7 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000001279 214.0
HFD1_k127_4116232_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000612 195.0
HFD1_k127_4116232_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000001244 154.0
HFD1_k127_4116830_0 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 492.0
HFD1_k127_4116830_1 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 463.0
HFD1_k127_4116830_2 - - - - 0.00000000000000000000000000000000000000000003524 165.0
HFD1_k127_4116830_3 carbon dioxide binding K04653,K04654 - - 0.00000000000000000000000000000009049 126.0
HFD1_k127_4116830_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564 2.1.2.2 0.00000000000000003185 91.0
HFD1_k127_4116830_5 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.0002835 49.0
HFD1_k127_4119406_0 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000001905 257.0
HFD1_k127_4119406_1 Putative esterase - - - 0.000000000000000000000000000000000000000000001005 181.0
HFD1_k127_4119406_2 belongs to the UPF0276 family K09930 - - 0.00000000000000332 85.0
HFD1_k127_4121808_0 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 382.0
HFD1_k127_4121808_1 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000004149 113.0
HFD1_k127_4121808_2 Lsr2 - - - 0.0006611 48.0
HFD1_k127_4131833_0 Tricorn protease PDZ domain K08676 - - 0.0 1526.0
HFD1_k127_4131833_1 beta-galactosidase activity K01190 - 3.2.1.23 7.953e-250 804.0
HFD1_k127_4131833_2 Glycogen debranching enzyme, glucanotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 376.0
HFD1_k127_4131833_3 hydroperoxide reductase activity - - - 0.000000000000000000000000000004446 122.0
HFD1_k127_4131833_4 hydroperoxide reductase activity - - - 0.0000000000000000003019 97.0
HFD1_k127_4131833_5 hydrolase activity, hydrolyzing O-glycosyl compounds K01176 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.1 0.000000000000000001483 88.0
HFD1_k127_413248_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 586.0
HFD1_k127_413248_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 365.0
HFD1_k127_413248_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000244 190.0
HFD1_k127_4133135_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 415.0
HFD1_k127_4133135_1 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 412.0
HFD1_k127_4133135_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 320.0
HFD1_k127_4133135_3 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000009334 188.0
HFD1_k127_4133135_4 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000000000000000000000000000003863 186.0
HFD1_k127_4133135_5 - - - - 0.00000000000000000000000000000000000000000573 160.0
HFD1_k127_4133135_6 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000001682 145.0
HFD1_k127_4133135_7 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000002581 113.0
HFD1_k127_4136006_0 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000001977 148.0
HFD1_k127_4136006_1 LemA family K03744 - - 0.00000001873 64.0
HFD1_k127_4136006_2 general secretion pathway protein K02457 - - 0.000006934 53.0
HFD1_k127_4137986_0 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000006311 257.0
HFD1_k127_4137986_1 MacB-like periplasmic core domain - - - 0.00000000000000001416 93.0
HFD1_k127_4137986_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00001436 49.0
HFD1_k127_4140996_0 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 434.0
HFD1_k127_4140996_1 Pfam:DUF1049 - - - 0.00000000000000000000006615 98.0
HFD1_k127_4141611_0 to Escherichia coli transposase for insertion sequence element IS21 IstA SW ISTA_ECOLI (P15025) (390 aa) fasta scores E() 3e-27, 33.1 id in 329 aa. Identical to the previously sequenced Yersinia pestis,Yersinia pseudotuberculosis and Escherichia coli pesticin plasmid insertion sequence transposase Y1055 TR P74993 (EMBL U59875) (340 aa) fasta scores E() 0, 100.0 id in 340 aa - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 329.0
HFD1_k127_4141611_1 IstB-like ATP binding protein - - - 0.0000000000004978 69.0
HFD1_k127_4144826_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 454.0
HFD1_k127_4144826_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 410.0
HFD1_k127_4144826_2 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.00000000000000000000000000001919 121.0
HFD1_k127_4147778_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 458.0
HFD1_k127_4147778_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000008187 169.0
HFD1_k127_4147778_2 Roadblock/LC7 domain - - - 0.0000000009086 66.0
HFD1_k127_4147778_3 Tetratricopeptide repeat - - - 0.00003454 56.0
HFD1_k127_4147778_4 Roadblock/LC7 domain K07131 - - 0.0001184 53.0
HFD1_k127_4149368_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000004081 233.0
HFD1_k127_4149368_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.00000000000000000000000000001806 122.0
HFD1_k127_4149368_2 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000000000000000009327 113.0
HFD1_k127_4149368_3 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000003035 100.0
HFD1_k127_4152790_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 437.0
HFD1_k127_4154869_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 491.0
HFD1_k127_4154869_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 398.0
HFD1_k127_4154869_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 387.0
HFD1_k127_4154869_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000008088 107.0
HFD1_k127_415739_0 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 380.0
HFD1_k127_415739_1 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002865 276.0
HFD1_k127_415739_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004483 292.0
HFD1_k127_415739_3 Domain of unknown function (DUF4321) - - - 0.000000000000000000002514 104.0
HFD1_k127_4157932_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 465.0
HFD1_k127_4157932_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000002497 160.0
HFD1_k127_4157932_2 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000003799 100.0
HFD1_k127_4157932_3 DoxX K15977 - - 0.00000001089 66.0
HFD1_k127_4157932_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000579 59.0
HFD1_k127_4157932_5 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0007723 51.0
HFD1_k127_4160881_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 338.0
HFD1_k127_4160881_1 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000332 192.0
HFD1_k127_4160881_2 Rhomboid family - - - 0.000000000000000000000000000000000000006142 156.0
HFD1_k127_4160881_3 Zn-dependent protease - - - 0.00000000000000002828 84.0
HFD1_k127_4160881_4 peptidyl-tyrosine sulfation - - - 0.000000874 62.0
HFD1_k127_4164606_0 efflux transmembrane transporter activity - - - 4.179e-305 960.0
HFD1_k127_4164606_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 318.0
HFD1_k127_4164606_2 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000001236 119.0
HFD1_k127_4164606_3 Cupin domain - - - 0.00000000000000000001799 94.0
HFD1_k127_4164804_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 7.917e-218 701.0
HFD1_k127_4164804_1 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001539 260.0
HFD1_k127_4164804_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000007426 180.0
HFD1_k127_4164804_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000971 95.0
HFD1_k127_4170955_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 573.0
HFD1_k127_4170955_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 321.0
HFD1_k127_4170955_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000002779 93.0
HFD1_k127_4170955_3 zinc-finger binding domain of transposase IS66 - - - 0.000000000000000001629 91.0
HFD1_k127_4170955_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000001025 70.0
HFD1_k127_4170955_5 Tetratricopeptide repeat - - - 0.00000001548 62.0
HFD1_k127_4170955_6 transposase activity - - - 0.000000236 52.0
HFD1_k127_4178063_0 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 332.0
HFD1_k127_4178063_1 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000004282 231.0
HFD1_k127_4180899_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000134 238.0
HFD1_k127_4180899_1 Major Facilitator Superfamily - - - 0.000001893 53.0
HFD1_k127_4182273_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 408.0
HFD1_k127_4191090_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 315.0
HFD1_k127_4191090_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000939 284.0
HFD1_k127_4191090_2 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000003458 214.0
HFD1_k127_4191090_3 PFAM Transposase DDE domain - - - 0.000000000000000000000003961 103.0
HFD1_k127_4191090_4 CoA binding domain - - - 0.000000000000005091 80.0
HFD1_k127_4199591_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 408.0
HFD1_k127_4199591_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000009175 159.0
HFD1_k127_4201743_0 Helix-turn-helix domain of transposase family ISL3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 397.0
HFD1_k127_4201743_1 Evidence 2b Function of strongly homologous gene - - - 0.0000000002899 61.0
HFD1_k127_4201743_2 - - - - 0.00001147 49.0
HFD1_k127_4208705_0 Alpha-amylase domain K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 372.0
HFD1_k127_4208705_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 314.0
HFD1_k127_4211722_0 - - - - 0.00000000000000000000000000000000000004478 156.0
HFD1_k127_4212410_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000001243 209.0
HFD1_k127_4212410_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000002765 116.0
HFD1_k127_4214289_0 xanthine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 483.0
HFD1_k127_4214289_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001026 261.0
HFD1_k127_4214289_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000004135 117.0
HFD1_k127_4230106_0 esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000008478 171.0
HFD1_k127_4230106_1 Protein of unknown function, DUF - - - 0.0000000000000000000000000005915 117.0
HFD1_k127_4230106_2 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000000002097 96.0
HFD1_k127_4230106_3 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000004628 79.0
HFD1_k127_4237422_0 Flp pilus polar localization response receiver ATPase TadZ, FlhG domain-containing K02282 - - 0.000000000000000000000000000000000000000000000005705 188.0
HFD1_k127_4237422_1 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000007572 142.0
HFD1_k127_424006_0 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000009621 156.0
HFD1_k127_424006_1 Alpha beta hydrolase - - - 0.0000000000007459 69.0
HFD1_k127_4243121_0 Response regulator, receiver K02485,K11355 - - 0.000000000000000000000000000000000001429 153.0
HFD1_k127_4243121_1 Belongs to the small heat shock protein (HSP20) family K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.0000000000000000000000000002574 125.0
HFD1_k127_4250479_0 PFAM Transposase, Mutator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 593.0
HFD1_k127_4250479_1 - - - - 0.0002543 44.0
HFD1_k127_4255679_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 576.0
HFD1_k127_4255679_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000001309 105.0
HFD1_k127_4257765_0 X-Pro dipeptidyl-peptidase domain protein K06978 - - 2.367e-257 839.0
HFD1_k127_4257765_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 482.0
HFD1_k127_4257765_2 - - - - 0.000000000000000000000000000000000000000000000000000000000003033 218.0
HFD1_k127_4257765_3 Fibronectin type 3 domain - - - 0.0000000000000000001592 94.0
HFD1_k127_4257765_4 Transcriptional regulator - - - 0.00000000000002905 78.0
HFD1_k127_4258750_0 Transposase and inactivated derivatives IS30 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006 287.0
HFD1_k127_4258750_1 Transposase and inactivated derivatives IS30 family K07482 - - 0.0000000000000000000000000000000000004983 140.0
HFD1_k127_425921_0 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000000000001165 220.0
HFD1_k127_425921_1 - - - - 0.000000000000000000005104 102.0
HFD1_k127_425921_2 COGs COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I K00784 - 3.1.26.11 0.0000000002753 61.0
HFD1_k127_4264820_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 424.0
HFD1_k127_4264820_1 PFAM Amidohydrolase 2 K03392,K07045 - 4.1.1.45 0.0000000000000000002075 88.0
HFD1_k127_42695_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 403.0
HFD1_k127_42695_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000929 287.0
HFD1_k127_4281319_0 Transposase, Mutator family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 404.0
HFD1_k127_4287300_0 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000001457 177.0
HFD1_k127_4287300_1 glycogen (starch) synthase activity - - - 0.000000000000000000002833 102.0
HFD1_k127_4287300_2 - - - - 0.0000000003278 67.0
HFD1_k127_4290240_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000006141 156.0
HFD1_k127_4294716_0 amine dehydrogenase activity K17285 - - 4.246e-233 739.0
HFD1_k127_4294716_1 ECF sigma factor - - - 0.0000000000000000000000000000000001716 138.0
HFD1_k127_4294716_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000002875 117.0
HFD1_k127_4294716_3 - - - - 0.00000001359 60.0
HFD1_k127_4304343_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000001461 172.0
HFD1_k127_4304343_1 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000009777 130.0
HFD1_k127_4310171_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 544.0
HFD1_k127_4310171_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000006396 204.0
HFD1_k127_4320204_0 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 503.0
HFD1_k127_4320204_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000008821 207.0
HFD1_k127_4320204_2 PglZ domain - - - 0.000000000000000000000000000000000000000000002064 166.0
HFD1_k127_4323147_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 481.0
HFD1_k127_4326426_0 Fibronectin type 3 domain - - - 4.826e-210 712.0
HFD1_k127_4326426_1 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000011 67.0
HFD1_k127_4326426_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000001269 77.0
HFD1_k127_4331164_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 349.0
HFD1_k127_4334246_0 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.000000000000000000000000162 116.0
HFD1_k127_4334246_1 DHH family K07462 - - 0.000000000000000002631 93.0
HFD1_k127_4346222_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 525.0
HFD1_k127_4346222_1 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 434.0
HFD1_k127_4346222_2 Protein of unknown function (DUF1207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001634 283.0
HFD1_k127_4357321_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 605.0
HFD1_k127_4357321_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000001178 181.0
HFD1_k127_4357321_2 Insulinase (Peptidase family M16) K07263 - - 0.000000000000004841 87.0
HFD1_k127_4365830_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 402.0
HFD1_k127_4365830_1 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000003016 170.0
HFD1_k127_4368059_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 538.0
HFD1_k127_4373967_0 Patatin-like phospholipase K07001 - - 0.00000000000000004331 86.0
HFD1_k127_4377373_0 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 302.0
HFD1_k127_4377373_1 Phospholipase/Carboxylesterase K06999,K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000165 243.0
HFD1_k127_4377373_2 Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000003253 177.0
HFD1_k127_4377373_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00005127 46.0
HFD1_k127_4389294_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000002329 198.0
HFD1_k127_4389294_1 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000002737 177.0
HFD1_k127_4397579_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 296.0
HFD1_k127_4397579_1 Rdx family K07401 - - 0.000000000000000000000000000000000000000144 153.0
HFD1_k127_4397579_2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 - - - 0.0000004597 58.0
HFD1_k127_4418480_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 392.0
HFD1_k127_4418480_1 transposase IS116 IS110 IS902 family - - - 0.00001222 57.0
HFD1_k127_442210_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 465.0
HFD1_k127_442210_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000001834 276.0
HFD1_k127_442210_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000001971 76.0
HFD1_k127_4439292_0 Cytoplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 402.0
HFD1_k127_4439292_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 346.0
HFD1_k127_4439292_2 COG4584 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009175 245.0
HFD1_k127_4439292_3 COG2801 Transposase and inactivated derivatives K07497 - - 0.00000000000000000000000000003039 121.0
HFD1_k127_4439292_4 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000005743 66.0
HFD1_k127_444740_0 PFAM Rhodopirellula transposase K01812,K02529,K16210 - 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 482.0
HFD1_k127_444740_1 PFAM Integrase, catalytic core - - - 0.0000000000000000000000000000272 117.0
HFD1_k127_445840_0 GMC oxidoreductase - - - 1.761e-255 795.0
HFD1_k127_445840_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 618.0
HFD1_k127_445840_2 Gluconate 2-dehydrogenase subunit 3 - - - 0.00000000000000000000000000000000000000000000000002797 202.0
HFD1_k127_445840_3 CAAX protease self-immunity - - - 0.00000003425 64.0
HFD1_k127_445840_4 NmrA-like family K15891 - 1.1.1.354 0.00002911 49.0
HFD1_k127_4459997_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 320.0
HFD1_k127_4459997_1 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
HFD1_k127_4459997_2 PFAM Transposase IS66 family K07484 - - 0.0005136 48.0
HFD1_k127_4460517_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.704e-256 797.0
HFD1_k127_4460517_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000001364 68.0
HFD1_k127_4466891_0 Sporulation related domain - - - 0.0000000000000000000000000004815 123.0
HFD1_k127_4477042_0 Involved in initiation control of chromosome replication K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 511.0
HFD1_k127_4477042_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000009188 150.0
HFD1_k127_4479782_0 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP) K20896 - - 0.000000000000000000000000000000000000000000000000000008184 196.0
HFD1_k127_4482002_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.674e-273 859.0
HFD1_k127_4482002_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000002882 170.0
HFD1_k127_4482002_2 cellulose binding - - - 0.000000004353 59.0
HFD1_k127_4500651_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 514.0
HFD1_k127_4500651_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 379.0
HFD1_k127_4500651_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000001266 128.0
HFD1_k127_4502975_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 530.0
HFD1_k127_4525011_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 513.0
HFD1_k127_45323_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002173 283.0
HFD1_k127_45323_1 - - - - 0.000000000002489 71.0
HFD1_k127_45323_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00009412 53.0
HFD1_k127_4535369_0 GGDEF domain - - - 0.000000000000007895 85.0
HFD1_k127_4547043_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000001169 201.0
HFD1_k127_4547043_1 Bax inhibitor 1 like - - - 0.000000000000000000000000000000000000000003716 162.0
HFD1_k127_459984_0 Nitroreductase family - - - 0.00000000000000000000000003116 110.0
HFD1_k127_459984_1 - - - - 0.0000000000000005548 85.0
HFD1_k127_459984_2 CBS domain - - - 0.0000000006594 68.0
HFD1_k127_4613281_0 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 400.0
HFD1_k127_4613281_1 relaxase mobilization nuclease domain protein - - - 0.0000000000000000000000002351 118.0
HFD1_k127_4613918_0 manually curated - - - 0.000000000000000000000000000000000000000000000000000002512 197.0
HFD1_k127_4613918_1 Transposase - - - 0.00000000000000000000000001264 114.0
HFD1_k127_4613918_2 SPTR A7NFQ2 Transposase and inactivated derivatives-like protein - - - 0.00000009774 59.0
HFD1_k127_4618521_0 COG0433 Predicted ATPase K06915 - - 2.855e-268 841.0
HFD1_k127_4618521_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000002383 188.0
HFD1_k127_4618521_2 COGs COG2380 conserved - - - 0.0000000000000000000000003294 121.0
HFD1_k127_4618521_3 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000009947 63.0
HFD1_k127_4631790_0 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 436.0
HFD1_k127_4631790_1 RibD C-terminal domain - - - 0.0000000000000000000001539 98.0
HFD1_k127_4640836_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 359.0
HFD1_k127_4643501_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 527.0
HFD1_k127_4643501_1 - - - - 0.00000000000000000000000007625 113.0
HFD1_k127_4643501_2 Belongs to the 'phage' integrase family K03733,K04763 - - 0.000000000804 61.0
HFD1_k127_4644719_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007403 280.0
HFD1_k127_4644719_1 type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000007015 229.0
HFD1_k127_4671361_0 ERAP1-like C-terminal domain K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 396.0
HFD1_k127_4671361_1 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005012 259.0
HFD1_k127_4671361_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000658 214.0
HFD1_k127_4671361_3 - - - - 0.0000000000000000000000000000000000000000000003264 177.0
HFD1_k127_4671361_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000007631 118.0
HFD1_k127_4686945_0 sptr a7nhu5 - - - 0.0000000000000000000000000000000000000000000000000000000000000002897 225.0
HFD1_k127_4686945_1 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000005454 171.0
HFD1_k127_4686945_2 PFAM Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000003781 133.0
HFD1_k127_4686945_3 DDE superfamily endonuclease - - - 0.00000000000000000000000000002871 130.0
HFD1_k127_4692996_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 6.835e-203 657.0
HFD1_k127_4692996_1 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001185 240.0
HFD1_k127_4692996_2 Domain of unknown function (DUF3597) - - - 0.0000000000000000000000000000000000000006062 153.0
HFD1_k127_4692996_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000002938 94.0
HFD1_k127_4692996_4 YCII-related domain - - - 0.0000004548 53.0
HFD1_k127_4692996_5 Protein of unknown function (DUF1152) - - - 0.00001207 49.0
HFD1_k127_4693935_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003776 247.0
HFD1_k127_4693935_1 Sodium:solute symporter family - - - 0.00000000000234 69.0
HFD1_k127_4707769_0 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000001568 214.0
HFD1_k127_4707769_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000005469 162.0
HFD1_k127_471857_0 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 0.000000000000000000001191 98.0
HFD1_k127_471857_1 SCO1/SenC K07152 - - 0.00000000008321 72.0
HFD1_k127_4739781_0 PFAM Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 296.0
HFD1_k127_4742241_0 long-chain fatty acid transport protein - - - 0.000000000000000000000002934 115.0
HFD1_k127_4755599_0 manually curated - - - 3.376e-212 662.0
HFD1_k127_4755599_1 Transposase DDE domain K07492 - - 0.00000000000000004227 84.0
HFD1_k127_4755599_2 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.0000000000001598 71.0
HFD1_k127_4755599_3 Putative transposase of IS4/5 family (DUF4096) K07492 - - 0.000158 44.0
HFD1_k127_4756450_0 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000006683 117.0
HFD1_k127_4756450_1 cytochrome c biogenesis protein - - - 0.00000000000000000000002791 107.0
HFD1_k127_4760007_0 Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 495.0
HFD1_k127_478741_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 473.0
HFD1_k127_4797868_0 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 300.0
HFD1_k127_4797868_1 PFAM IS1 transposase K07480 - - 0.000000000000000000000000000000000001151 153.0
HFD1_k127_4797868_2 Transcriptional regulator K02529 - - 0.000000000000000000000000000000000004162 141.0
HFD1_k127_4797868_3 Methyltransferase domain - - - 0.0000000324 57.0
HFD1_k127_4801756_0 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000001373 188.0
HFD1_k127_4801756_1 HD domain - - - 0.0000000000000000000000000000319 128.0
HFD1_k127_4808867_0 - - - - 0.000000000000000000000000002131 116.0
HFD1_k127_4808867_1 - - - - 0.000002042 53.0
HFD1_k127_4810_0 DoxX - - - 0.00000000000000000000000000000000000000000000000001912 188.0
HFD1_k127_4810_1 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000002271 111.0
HFD1_k127_4820353_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 402.0
HFD1_k127_4820353_1 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 312.0
HFD1_k127_4820353_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000006806 201.0
HFD1_k127_4820353_3 OmpA family K03640 - - 0.00000000000000000000000000000000000000000786 162.0
HFD1_k127_4820353_4 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000005367 152.0
HFD1_k127_4820353_5 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000005038 139.0
HFD1_k127_4820353_6 TonB C terminal K03832 - - 0.000000000000000000000001596 115.0
HFD1_k127_4826366_0 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 321.0
HFD1_k127_4832890_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 571.0
HFD1_k127_4832890_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 318.0
HFD1_k127_4836035_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 331.0
HFD1_k127_4836035_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000001807 120.0
HFD1_k127_4836035_2 Bacterial Ig-like domain 2 - - - 0.000000000000000001702 98.0
HFD1_k127_4837233_0 - - - - 0.0005997 43.0
HFD1_k127_4837233_1 Pilus assembly protein PilX K02673 - - 0.0006063 53.0
HFD1_k127_4837886_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 527.0
HFD1_k127_4837886_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 466.0
HFD1_k127_4837886_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000001341 116.0
HFD1_k127_4837886_3 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000001257 115.0
HFD1_k127_4838306_0 Methyl-viologen-reducing hydrogenase, delta subunit K02572,K02573,K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003146 278.0
HFD1_k127_4838306_1 Transcriptional regulator - - - 0.0000000000000000000000006227 111.0
HFD1_k127_4838306_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000114 85.0
HFD1_k127_4847162_0 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 336.0
HFD1_k127_4847162_1 Belongs to the universal stress protein A family - - - 0.00000001854 57.0
HFD1_k127_4855222_0 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 308.0
HFD1_k127_4855222_1 Formate/nitrite transporter K06212,K21993 - - 0.00000000000000000000000000000000000000000000000000007591 199.0
HFD1_k127_4855222_2 Formate/nitrite transporter K06212,K21993 - - 0.0000000000000000000000000000000000000000000000005958 185.0
HFD1_k127_4855222_3 Hemolysin III K11068 - - 0.00000000000001759 73.0
HFD1_k127_4855222_4 - - - - 0.00000000000006329 73.0
HFD1_k127_4862140_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 324.0
HFD1_k127_4862140_1 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000003488 121.0
HFD1_k127_4862140_2 metallocarboxypeptidase activity K14054 - - 0.000000000000000000004121 98.0
HFD1_k127_4862140_3 Domain of unknown function (DUF1707) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000002191 61.0
HFD1_k127_4862391_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000003066 255.0
HFD1_k127_4862403_0 BNR Asp-box repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 572.0
HFD1_k127_4862403_2 Virulence activator alpha C-term - - - 0.0000000000000000000165 101.0
HFD1_k127_4862417_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 352.0
HFD1_k127_4862417_1 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 324.0
HFD1_k127_4862417_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 308.0
HFD1_k127_4862417_3 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003929 247.0
HFD1_k127_4862417_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000005958 230.0
HFD1_k127_4862417_5 Tfp pilus assembly protein FimV K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000005475 204.0
HFD1_k127_4862417_6 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000002493 52.0
HFD1_k127_4862417_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000835 50.0
HFD1_k127_4868376_0 Asparaginase K01444 - 3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 375.0
HFD1_k127_4868376_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 350.0
HFD1_k127_4868376_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004224 258.0
HFD1_k127_4871032_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 6.285e-301 936.0
HFD1_k127_4871032_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 461.0
HFD1_k127_4871032_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005362 275.0
HFD1_k127_4871032_3 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000004184 252.0
HFD1_k127_4871032_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000001866 116.0
HFD1_k127_4871672_0 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
HFD1_k127_4871672_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000006418 195.0
HFD1_k127_4871672_2 Transcriptional Regulator, AraC family - - - 0.000000000000000000000002616 105.0
HFD1_k127_4875095_0 Transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 319.0
HFD1_k127_4875095_1 Transposase DDE domain group 1 - - - 0.00000000000000002437 82.0
HFD1_k127_4876693_0 Belongs to the peptidase S16 family - - - 4.634e-240 766.0
HFD1_k127_4876693_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 295.0
HFD1_k127_4876693_2 Nitroreductase family - - - 0.00000000000000000000003371 114.0
HFD1_k127_4876763_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 432.0
HFD1_k127_4876763_1 COG4313 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000001216 203.0
HFD1_k127_4877742_0 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000002121 216.0
HFD1_k127_4877742_1 acetyltransferase - - - 0.0000000000000002914 80.0
HFD1_k127_4877742_2 PAP2 superfamily - - - 0.000000000000009848 87.0
HFD1_k127_4881891_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000003654 217.0
HFD1_k127_4881891_1 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000001584 188.0
HFD1_k127_4881891_2 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000000001606 173.0
HFD1_k127_4882020_0 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 347.0
HFD1_k127_4883035_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000004742 212.0
HFD1_k127_4883035_1 Tetratricopeptide repeat K08309 - - 0.0000000000000000000000000000000000000002149 168.0
HFD1_k127_4883035_2 Cold shock K03704 - - 0.00000000000000000000000000000003369 130.0
HFD1_k127_4883517_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004767 221.0
HFD1_k127_4883517_1 Histidine kinase K13598 - 2.7.13.3 0.0000009014 58.0
HFD1_k127_4884932_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 463.0
HFD1_k127_4884932_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 449.0
HFD1_k127_4884932_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002188 273.0
HFD1_k127_4885108_0 Amidohydrolase family - - - 0.0 1163.0
HFD1_k127_4885108_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000001668 266.0
HFD1_k127_4885108_2 SURF1 family K14998 - - 0.0000000000000000000000000000000006658 139.0
HFD1_k127_4885108_3 GIY-YIG catalytic domain K07461 - - 0.000005206 49.0
HFD1_k127_4889696_0 Glycosyltransferase 36 associated - - - 2.345e-258 816.0
HFD1_k127_4889696_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 8.133e-197 625.0
HFD1_k127_4889696_2 ABC transporter K10112,K11072,K17324 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 349.0
HFD1_k127_4892563_0 Transposase IS116 IS110 IS902 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001047 270.0
HFD1_k127_4892563_1 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000008265 219.0
HFD1_k127_4892563_2 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000224 188.0
HFD1_k127_4892563_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000008885 157.0
HFD1_k127_4892563_4 transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000008646 123.0
HFD1_k127_4892563_5 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000009311 125.0
HFD1_k127_489631_0 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 329.0
HFD1_k127_489631_1 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 309.0
HFD1_k127_48971_0 PFAM Integrase catalytic K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 531.0
HFD1_k127_48971_1 Transposase K07483 - - 0.0000000000000000000000000000000000000000000002299 168.0
HFD1_k127_4900326_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 1227.0
HFD1_k127_4902991_0 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 424.0
HFD1_k127_4902991_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 387.0
HFD1_k127_4902991_2 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000006021 265.0
HFD1_k127_4903215_0 PFAM Amino acid K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002747 297.0
HFD1_k127_4903215_1 Conserved repeat domain - - - 0.000000000000000000000000000000002809 148.0
HFD1_k127_4903215_2 Acid phosphatase homologues - - - 0.00000000000436 72.0
HFD1_k127_4904724_0 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 290.0
HFD1_k127_4910208_0 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 540.0
HFD1_k127_4910208_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000002397 56.0
HFD1_k127_4912760_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000008862 232.0
HFD1_k127_4912760_3 Domain of unknown function (DUF1918) - - - 0.00000000001731 67.0
HFD1_k127_4915111_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 381.0
HFD1_k127_4917576_0 phosphorelay signal transduction system K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004944 279.0
HFD1_k127_4917576_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000003886 197.0
HFD1_k127_4917576_2 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000007212 147.0
HFD1_k127_4921291_0 Methyl-viologen-reducing hydrogenase, delta subunit K02572,K02573,K03522 - - 0.00000000000000000000000000000000000000000000009464 179.0
HFD1_k127_4921291_1 Transcriptional regulator - - - 0.0000000000000000000000005388 108.0
HFD1_k127_4921984_0 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 564.0
HFD1_k127_4921984_1 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 394.0
HFD1_k127_4921984_2 Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 291.0
HFD1_k127_4921984_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000582 102.0
HFD1_k127_4921984_4 - - - - 0.00000000000001022 80.0
HFD1_k127_4921984_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000002506 64.0
HFD1_k127_4921984_6 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0033554,GO:0033592,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 0.00003808 56.0
HFD1_k127_4925580_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 335.0
HFD1_k127_4925580_1 Major facilitator Superfamily K08178 - - 0.000000000000000000000000000000000000000000000000000000001582 214.0
HFD1_k127_4929917_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000005135 229.0
HFD1_k127_4930143_0 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000004597 169.0
HFD1_k127_4930143_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000001152 125.0
HFD1_k127_4933079_0 peptidyl-tyrosine sulfation - - - 0.0000000004163 70.0
HFD1_k127_4948286_0 Protein of unknown function (DUF2867) - - - 8.633e-220 692.0
HFD1_k127_4948286_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 320.0
HFD1_k127_4948286_2 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005206 240.0
HFD1_k127_4948286_3 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000002872 236.0
HFD1_k127_4948286_4 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000002036 221.0
HFD1_k127_4948286_5 Transposase - - - 0.0000000000000000000000000000000000000000000001401 171.0
HFD1_k127_4948286_6 Transposase - - - 0.00000000000000000000000000000000003118 136.0
HFD1_k127_4948286_7 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 - - - 0.00000000000000000004264 93.0
HFD1_k127_4948286_8 Transposase - - - 0.00000000004905 70.0
HFD1_k127_4949007_0 - - - - 0.00000000000000000000000000000000000000000000000000000031 213.0
HFD1_k127_4949007_1 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000008281 177.0
HFD1_k127_4954082_0 PFAM transposase, IS4 family protein - - - 3.884e-194 614.0
HFD1_k127_4954365_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001733 271.0
HFD1_k127_4954772_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 306.0
HFD1_k127_4956924_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 317.0
HFD1_k127_4956924_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000006674 187.0
HFD1_k127_4958731_0 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 457.0
HFD1_k127_4958731_1 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 413.0
HFD1_k127_4958731_2 - - - - 0.00000007123 61.0
HFD1_k127_4958731_3 peptidase dimerisation domain protein - - - 0.0003393 47.0
HFD1_k127_4960379_0 Polysaccharide lyase family 4, domain III - - - 0.000000000000000000000000000000001942 143.0
HFD1_k127_4960379_1 3-beta hydroxysteroid dehydrogenase isomerase K21793 - - 0.000000259 55.0
HFD1_k127_4960594_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000001064 226.0
HFD1_k127_4963177_0 transposase IS116 IS110 IS902 family protein - - - 1.913e-206 647.0
HFD1_k127_4963972_0 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000008844 198.0
HFD1_k127_4963972_1 PFAM Amidohydrolase 2 K01686 - 4.2.1.8 0.000000000000000006796 96.0
HFD1_k127_4963972_3 Domain of unknown function (DUF4382) - - - 0.000000000000007411 87.0
HFD1_k127_4963972_4 Bacterial Ig-like domain 2 - - - 0.000000002349 70.0
HFD1_k127_4963972_5 Capsule assembly protein Wzi - - - 0.00003328 55.0
HFD1_k127_4969234_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 404.0
HFD1_k127_4969234_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000003901 246.0
HFD1_k127_4974915_0 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000015 282.0
HFD1_k127_4974915_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000595 125.0
HFD1_k127_4977578_0 Carbohydrate family 9 binding domain-like - - - 1.176e-282 893.0
HFD1_k127_4977578_1 protein import - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 422.0
HFD1_k127_4977578_2 peptidyl-tyrosine sulfation K13992 - - 0.00000000000000000000000000000000000000000000000000027 194.0
HFD1_k127_4977578_3 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0007745 42.0
HFD1_k127_4978149_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 474.0
HFD1_k127_4978149_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000002528 64.0
HFD1_k127_4978149_2 - - - - 0.00002038 50.0
HFD1_k127_4978359_0 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000533 216.0
HFD1_k127_4978359_1 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000001209 143.0
HFD1_k127_4978359_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000001633 98.0
HFD1_k127_4978359_3 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000007326 65.0
HFD1_k127_4978359_4 Polysulphide reductase, NrfD K00185 - - 0.00000007742 54.0
HFD1_k127_4986394_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000051 222.0
HFD1_k127_4986394_1 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000003646 175.0
HFD1_k127_4992772_0 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 334.0
HFD1_k127_4992772_1 4Fe-4S single cluster domain K07001 - - 0.000004772 53.0
HFD1_k127_4994400_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000007384 90.0
HFD1_k127_4994400_1 - - - - 0.00000000004132 75.0
HFD1_k127_4994400_2 DNA-templated transcription, initiation - - - 0.00008506 49.0
HFD1_k127_4998836_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 450.0
HFD1_k127_4998836_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000002415 96.0
HFD1_k127_5000972_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 329.0
HFD1_k127_5003227_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000006035 218.0
HFD1_k127_5003227_1 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000001208 162.0
HFD1_k127_5003361_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003661 264.0
HFD1_k127_5003361_1 HD domain - - - 0.00000000000000000000000001732 111.0
HFD1_k127_5005883_0 HTH-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003566 229.0
HFD1_k127_5005883_1 Transposase K07483 - - 0.000000000000000000000000000000000000000000003255 166.0
HFD1_k127_5005883_2 Transposase and inactivated derivatives IS30 family - - - 0.000000000000000000008664 92.0
HFD1_k127_5012527_0 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000001895 161.0
HFD1_k127_5012527_1 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000004901 128.0
HFD1_k127_5012527_2 GTPase activity K03650 - - 0.000000000000006484 77.0
HFD1_k127_5015178_0 Insertion element 4 transposase N-terminal - - - 6.843e-213 666.0
HFD1_k127_5015178_1 Belongs to the glycosyl hydrolase 1 family K01223 - 3.2.1.86 0.0000000000000000000000000000009402 126.0
HFD1_k127_5019172_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000001471 208.0
HFD1_k127_5019172_1 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000001004 98.0
HFD1_k127_5019300_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.00000000000000000000000000000001876 128.0
HFD1_k127_5019300_1 Sodium/hydrogen exchanger family - - - 0.00000000000000002193 95.0
HFD1_k127_5020956_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 348.0
HFD1_k127_5020956_1 PFAM Transposase DDE domain - - - 0.000000000000000000001215 98.0
HFD1_k127_5022530_0 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 280.0
HFD1_k127_5022530_1 Poly (ADP-ribose) glycohydrolase (PARG) - - - 0.0000000000000000000000000000000000000000000000000001317 202.0
HFD1_k127_5023248_0 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 471.0
HFD1_k127_5023248_1 Bacterial dnaA protein K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 434.0
HFD1_k127_5023248_2 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.000000000000000000000000000000000001827 159.0
HFD1_k127_5024317_0 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 453.0
HFD1_k127_5024317_1 - - - - 0.0000000000000000000000000000000000000002138 154.0
HFD1_k127_5024317_2 hydroperoxide reductase activity K01607 - 4.1.1.44 0.0000000000000000000000000000001226 125.0
HFD1_k127_5024317_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000001126 97.0
HFD1_k127_5026089_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 547.0
HFD1_k127_5026089_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000134 96.0
HFD1_k127_5027162_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 393.0
HFD1_k127_5027162_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 294.0
HFD1_k127_5027162_2 MacB-like periplasmic core domain K02004 - - 0.000000000000001957 81.0
HFD1_k127_5031239_0 Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 331.0
HFD1_k127_5032465_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 477.0
HFD1_k127_5032465_1 histidine kinase A domain protein - - - 0.00000009963 63.0
HFD1_k127_5033433_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 479.0
HFD1_k127_5033433_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000001656 77.0
HFD1_k127_5036255_0 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.00000009053 63.0
HFD1_k127_5036680_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 497.0
HFD1_k127_5036680_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000002249 116.0
HFD1_k127_5036680_2 Domain of unknown function (DUF4136) - - - 0.00000000000001873 82.0
HFD1_k127_5036680_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000002061 78.0
HFD1_k127_5036680_4 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.00000221 49.0
HFD1_k127_5038179_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.762e-236 753.0
HFD1_k127_5038179_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000008314 217.0
HFD1_k127_5038179_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000002499 216.0
HFD1_k127_5038179_3 - - - - 0.00000000000000000000000000000004297 146.0
HFD1_k127_5038179_4 - - - - 0.0000000000000000000000000002188 115.0
HFD1_k127_5038179_5 Hsp20/alpha crystallin family K13993 - - 0.00000003565 57.0
HFD1_k127_5047607_0 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000174 277.0
HFD1_k127_5047607_1 TrkA-C domain K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004728 261.0
HFD1_k127_5047607_2 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002808 255.0
HFD1_k127_5047607_3 - - - - 0.0000000000188 72.0
HFD1_k127_505416_0 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000008589 199.0
HFD1_k127_505416_1 Alpha amylase catalytic - - - 0.000000000000000000000000000000000000000000000008724 173.0
HFD1_k127_5054889_0 Transposase K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 474.0
HFD1_k127_5054889_1 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000000000000000000000000000000000000008499 201.0
HFD1_k127_5060897_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 1.324e-230 726.0
HFD1_k127_5060897_1 TonB-dependent Receptor Plug K02014,K16089 - - 0.000000000000000000000000000000000000002074 168.0
HFD1_k127_5060897_2 Transglycosylase associated protein - - - 0.000000000000000000000003263 104.0
HFD1_k127_5060897_3 Peptidase C26 K01658 - 4.1.3.27 0.000000000000846 68.0
HFD1_k127_5060897_5 - - - - 0.0000001187 61.0
HFD1_k127_5075864_0 PFAM ATPase associated with various cellular activities AAA_3 - - - 0.0000000000000000000000000000000000000000000000000000000000953 218.0
HFD1_k127_5083123_0 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 328.0
HFD1_k127_5083123_1 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 259.0
HFD1_k127_5083123_2 - - - - 0.00000000000000000000000269 113.0
HFD1_k127_5088292_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 593.0
HFD1_k127_5088292_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 346.0
HFD1_k127_5088292_2 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003199 281.0
HFD1_k127_5088292_3 Flagellar rod assembly protein muramidase FlgJ K02395,K08259,K08309,K21472 - 3.4.24.75 0.00000000000000000000000004277 121.0
HFD1_k127_5088292_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000004315 118.0
HFD1_k127_5088292_5 23S rRNA-intervening sequence protein - - - 0.00000000000000306 80.0
HFD1_k127_5088292_6 Polymer-forming cytoskeletal - - - 0.00000000001195 70.0
HFD1_k127_5099334_0 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 565.0
HFD1_k127_5105420_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 432.0
HFD1_k127_5105420_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 380.0
HFD1_k127_5105420_2 transposase activity K07497 - - 0.00000000000000000000000000000000000000000000000000000009551 205.0
HFD1_k127_5105420_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000002451 147.0
HFD1_k127_5111320_0 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 547.0
HFD1_k127_5111320_1 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 310.0
HFD1_k127_5111320_2 Glyoxalase-like domain - - - 0.00008505 48.0
HFD1_k127_5113915_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 467.0
HFD1_k127_5113915_1 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 364.0
HFD1_k127_5113915_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002103 246.0
HFD1_k127_5113915_3 ABC-2 type transporter - - - 0.0000002007 55.0
HFD1_k127_5117453_0 Serine hydrolase (FSH1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 509.0
HFD1_k127_5118339_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 526.0
HFD1_k127_5118339_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000001597 141.0
HFD1_k127_5118339_2 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000008277 89.0
HFD1_k127_5118339_3 - - - - 0.000000000000007633 81.0
HFD1_k127_5118339_4 Sugar-specific transcriptional regulator TrmB - - - 0.000000005018 66.0
HFD1_k127_5128886_0 BON domain K04065 - - 0.00000000000000000000000000000000000000000000000000001405 201.0
HFD1_k127_5128886_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00002341 55.0
HFD1_k127_5128886_3 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0002219 53.0
HFD1_k127_5128886_4 Transglutaminase-like superfamily - - - 0.0002282 50.0
HFD1_k127_5135655_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 363.0
HFD1_k127_5138886_0 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 312.0
HFD1_k127_5138886_1 ABC-type sugar transport systems, permease components K02025 - - 0.00000000000000000000000000000000000001158 151.0
HFD1_k127_514290_0 Domain of unknown function (DUF1611_C) P-loop domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 322.0
HFD1_k127_514290_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde - - - 0.00005899 51.0
HFD1_k127_5145272_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 351.0
HFD1_k127_5145272_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 303.0
HFD1_k127_5147928_0 IMP dehydrogenase / GMP reductase domain K22083 - 2.1.1.21 0.0000000000000000000000003768 109.0
HFD1_k127_5147928_1 Belongs to the ParB family K03497 - - 0.00000001076 66.0
HFD1_k127_5151395_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
HFD1_k127_5151395_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000002627 181.0
HFD1_k127_5151395_2 - - - - 0.00001581 48.0
HFD1_k127_5153298_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 421.0
HFD1_k127_5153298_1 Phospholipid methyltransferase - - - 0.00000000000000008414 90.0
HFD1_k127_51661_0 PFAM transposase, IS4 family protein - - - 8.416e-215 680.0
HFD1_k127_51661_1 iron dependent repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 595.0
HFD1_k127_51661_2 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000043 259.0
HFD1_k127_5167403_0 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 360.0
HFD1_k127_5167403_1 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000003155 177.0
HFD1_k127_5174756_0 HAMP domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000007254 277.0
HFD1_k127_517692_0 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 608.0
HFD1_k127_517692_1 Group II intron, maturase-specific domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 505.0
HFD1_k127_517692_2 Signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000001012 192.0
HFD1_k127_517692_3 Group II intron, maturase-specific domain - - - 0.00000000000000000000000002396 112.0
HFD1_k127_517692_4 - - - - 0.00000000000000000001877 94.0
HFD1_k127_517692_5 PFAM transposase IS3 IS911 family protein K07483 - - 0.00000000000002867 76.0
HFD1_k127_517692_7 diguanylate cyclase - - - 0.000000000002747 70.0
HFD1_k127_5185670_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 353.0
HFD1_k127_5185670_1 GHMP kinase - - - 0.00000000000000000007532 103.0
HFD1_k127_5186834_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1025.0
HFD1_k127_5186834_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 338.0
HFD1_k127_5186834_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000002274 286.0
HFD1_k127_5186834_3 integral membrane protein K07027 - - 0.0000000000000000000002998 110.0
HFD1_k127_5186834_4 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits - - - 0.000000000000000004435 98.0
HFD1_k127_5244064_0 Domain of unknown function (DUF4153) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 302.0
HFD1_k127_5244064_1 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000001569 161.0
HFD1_k127_5244064_2 Protein conserved in bacteria K09984 - - 0.000000000000000000000000000000001895 129.0
HFD1_k127_524551_0 Mu transposase, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 531.0
HFD1_k127_524551_1 Type II secretory pathway, component ExeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 342.0
HFD1_k127_524551_2 - - - - 0.000000000000000000000000000000000000000000000001684 180.0
HFD1_k127_524551_4 Belongs to the 'phage' integrase family - - - 0.0001528 51.0
HFD1_k127_5248732_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001445 291.0
HFD1_k127_5248732_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000007275 151.0
HFD1_k127_52525_0 PFAM transposase, IS4 family protein - - - 2.501e-201 642.0
HFD1_k127_5258465_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 473.0
HFD1_k127_5258465_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006565 267.0
HFD1_k127_5258465_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000002492 240.0
HFD1_k127_5258465_3 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000001231 134.0
HFD1_k127_5258465_4 - - - - 0.00004023 50.0
HFD1_k127_5266054_0 Zinc carboxypeptidase - - - 7.18e-206 664.0
HFD1_k127_5266054_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 321.0
HFD1_k127_5266054_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003293 251.0
HFD1_k127_5318865_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000001722 241.0
HFD1_k127_5318865_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000005473 168.0
HFD1_k127_5321356_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 333.0
HFD1_k127_5321356_1 TIGRFAM phosphate ABC transporter K02038 - - 0.0000000000000000000000000000000000000000002991 161.0
HFD1_k127_5325185_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 540.0
HFD1_k127_5325185_1 Bacterial dnaA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 426.0
HFD1_k127_5325185_2 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000531 155.0
HFD1_k127_5325185_3 - - - - 0.0004623 46.0
HFD1_k127_5327573_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 266.0
HFD1_k127_5327573_1 4Fe-4S binding domain - - - 0.00000000000008988 81.0
HFD1_k127_5328052_0 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 520.0
HFD1_k127_5328052_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 292.0
HFD1_k127_5328052_2 PFAM Outer membrane protein, OmpA MotB, C-terminal K02557 - - 0.0000000004453 61.0
HFD1_k127_533037_0 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
HFD1_k127_533037_2 Protein of unknown function (DUF998) - - - 0.0002502 51.0
HFD1_k127_5331843_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 486.0
HFD1_k127_5331843_1 Outer membrane efflux protein - - - 0.0000000429 66.0
HFD1_k127_5340468_0 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 426.0
HFD1_k127_5340468_1 - - - - 0.000000000000000000000000000000000000000000004812 179.0
HFD1_k127_5340468_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000001312 96.0
HFD1_k127_534437_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 356.0
HFD1_k127_534437_1 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000004625 148.0
HFD1_k127_5356030_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 317.0
HFD1_k127_5356030_1 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000157 202.0
HFD1_k127_5356030_2 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000002684 73.0
HFD1_k127_536100_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 640.0
HFD1_k127_536100_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 285.0
HFD1_k127_5372795_0 PFAM cytochrome c oxidase subunit I K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 532.0
HFD1_k127_5372795_1 PFAM Cytochrome C oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000001885 185.0
HFD1_k127_5372795_2 Serine Threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000007947 181.0
HFD1_k127_5372795_3 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000001408 195.0
HFD1_k127_5372795_4 PFAM Oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000005097 162.0
HFD1_k127_5372795_5 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000005694 61.0
HFD1_k127_5390508_0 transposition, DNA-mediated K02342 - 2.7.7.7 0.00000000000000000000000000000000000153 152.0
HFD1_k127_5390945_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000002576 140.0
HFD1_k127_5390945_1 TonB-dependent Receptor Plug Domain - - - 0.00000000002441 76.0
HFD1_k127_5394100_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 470.0
HFD1_k127_5411140_0 COGs COG4584 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000196 235.0
HFD1_k127_5411140_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000001261 151.0
HFD1_k127_5411140_2 COG1484 DNA replication protein - - - 0.0000000000000000000000000000000000004551 153.0
HFD1_k127_5411140_3 chromosome segregation - - - 0.0000000000001065 84.0
HFD1_k127_5413871_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000006105 163.0
HFD1_k127_5413871_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000058 168.0
HFD1_k127_5413871_2 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000000000000000006176 103.0
HFD1_k127_5413871_3 N-acyl-D-aspartate D-glutamate deacylase K01465,K06015 - 3.5.1.81,3.5.2.3 0.0000000000004221 73.0
HFD1_k127_5418863_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1784.0
HFD1_k127_5418863_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 550.0
HFD1_k127_5442429_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 407.0
HFD1_k127_5442429_1 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000008969 138.0
HFD1_k127_5442429_2 - - - - 0.0000000000000000000000000000000413 140.0
HFD1_k127_5442429_3 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000002403 89.0
HFD1_k127_5442429_4 - - - - 0.000000003578 70.0
HFD1_k127_5454114_0 Orn Lys Arg decarboxylase K01582,K01584 - 4.1.1.18,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 451.0
HFD1_k127_5454114_1 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003561 280.0
HFD1_k127_5480336_0 COG4584 Transposase and inactivated derivatives - - - 1.197e-266 827.0
HFD1_k127_5480336_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 423.0
HFD1_k127_5480336_2 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 367.0
HFD1_k127_5480336_3 Transposase DDE domain - - - 0.000000001473 61.0
HFD1_k127_5522490_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000003118 189.0
HFD1_k127_5522490_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000002096 73.0
HFD1_k127_5533081_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 460.0
HFD1_k127_5536652_0 PFAM Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 318.0
HFD1_k127_5554016_0 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 377.0
HFD1_k127_5554016_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000001258 218.0
HFD1_k127_5554016_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000697 113.0
HFD1_k127_5554016_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000001064 78.0
HFD1_k127_5560548_0 impB/mucB/samB family K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000001589 218.0
HFD1_k127_5560548_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000001566 70.0
HFD1_k127_5560548_2 Cupin 2, conserved barrel domain protein - - - 0.0005081 44.0
HFD1_k127_5589908_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000000000000000000000000000000000000000000000000000012 227.0
HFD1_k127_5589908_1 ATPase with chaperone activity - - - 0.0000000000000000000000000000000000000000000000004773 179.0
HFD1_k127_5589908_2 23S rRNA-intervening sequence protein - - - 0.000000000000006383 79.0
HFD1_k127_5589908_3 - - - - 0.00000000005309 71.0
HFD1_k127_5599468_0 Tn3 transposase DDE domain - - - 2.672e-210 671.0
HFD1_k127_5599468_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002904 266.0
HFD1_k127_5605109_0 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 516.0
HFD1_k127_5605109_1 - - - - 0.0000000000000000000004442 96.0
HFD1_k127_5607668_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000006704 268.0
HFD1_k127_5628347_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 2.049e-279 873.0
HFD1_k127_5628347_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000002093 219.0
HFD1_k127_5628347_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000002473 61.0
HFD1_k127_5628741_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 412.0
HFD1_k127_5629121_0 TonB-dependent receptor - - - 5.698e-228 741.0
HFD1_k127_5629121_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004233 232.0
HFD1_k127_5629379_0 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000006881 166.0
HFD1_k127_5629379_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000001995 152.0
HFD1_k127_5629379_2 PFAM Lipocalin family protein K03098 - - 0.000000000000000000000002377 104.0
HFD1_k127_5632306_0 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 306.0
HFD1_k127_5632306_1 - - - - 0.000000000000000000000000000000001352 134.0
HFD1_k127_5632306_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000805 80.0
HFD1_k127_5632306_3 - - - - 0.00000000000001339 86.0
HFD1_k127_5632722_0 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000005069 141.0
HFD1_k127_5632722_1 protein with SCP PR1 domains - - - 0.0000000000000000000000000009515 118.0
HFD1_k127_5632722_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000001365 103.0
HFD1_k127_5632722_3 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000001084 89.0
HFD1_k127_5635707_0 Belongs to the thiolase family K07508 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 445.0
HFD1_k127_5635707_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000001031 216.0
HFD1_k127_5635707_2 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000001132 183.0
HFD1_k127_5636001_0 DNA restriction-modification system - - - 0.0000000000000000000000000000000000000000000000000000000000005334 229.0
HFD1_k127_5636001_1 - - - - 0.00000000000000000000000145 105.0
HFD1_k127_5636207_0 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000001279 138.0
HFD1_k127_5636207_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000009076 134.0
HFD1_k127_5636207_2 6-pyruvoyl tetrahydrobiopterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000003485 100.0
HFD1_k127_5637388_0 Belongs to the peptidase S8 family - - - 0.00007322 56.0
HFD1_k127_5640465_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K01990,K09691,K09693 - 3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000006731 246.0
HFD1_k127_5640465_2 Transport permease protein K09690 - - 0.00002848 47.0
HFD1_k127_5640643_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 563.0
HFD1_k127_5640643_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 304.0
HFD1_k127_5640643_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000002409 192.0
HFD1_k127_5640643_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000167 128.0
HFD1_k127_5642640_0 domain protein K13735 - - 0.00004054 56.0
HFD1_k127_5646102_0 Large extracellular alpha-helical protein K06894 - - 1.597e-205 662.0
HFD1_k127_5647200_0 Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008256 374.0
HFD1_k127_5647200_1 Methyltransferase domain - - - 0.000000000000000000000000003351 116.0
HFD1_k127_5647609_0 Transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 378.0
HFD1_k127_5647609_1 Transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 299.0
HFD1_k127_5647609_2 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000848 258.0
HFD1_k127_5647609_3 Transposase - - - 0.000000000000000000000000000001424 131.0
HFD1_k127_5647609_4 bacterial-type flagellum organization - - - 0.000000000000000003667 90.0
HFD1_k127_5647609_5 Transposase - - - 0.00000000000000001123 91.0
HFD1_k127_5647609_6 Transposase - - - 0.0000000000000000577 82.0
HFD1_k127_5647609_7 Domain of unknown function (DUF4145) - - - 0.000000000000000466 85.0
HFD1_k127_5647609_8 - - - - 0.0000000324 57.0
HFD1_k127_5652370_0 Glucose inhibited division protein A K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000003414 207.0
HFD1_k127_5652370_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000004014 150.0
HFD1_k127_5652370_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000001839 71.0
HFD1_k127_5653946_0 Evidence 2b Function of strongly homologous gene K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 448.0
HFD1_k127_5653946_1 Lsr2 - GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009628,GO:0009636,GO:0009889,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031668,GO:0033554,GO:0034641,GO:0040007,GO:0042221,GO:0042262,GO:0042493,GO:0042542,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.0000002631 55.0
HFD1_k127_5654484_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000001504 254.0
HFD1_k127_5654484_1 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000003546 116.0
HFD1_k127_5654484_2 Transcriptional regulator - - - 0.000000000000000000002428 100.0
HFD1_k127_5654484_3 Iron-sulfur cluster assembly protein - - - 0.000000000000000002465 99.0
HFD1_k127_5654484_4 Uncharacterized conserved protein (DUF2249) - - - 0.000000000004327 76.0
HFD1_k127_5654587_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000009305 155.0
HFD1_k127_5654587_1 Outer membrane protein (OmpH-like) K06142 - - 0.000000000001081 73.0
HFD1_k127_5654893_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000002737 177.0
HFD1_k127_5654893_1 - - - - 0.00006972 55.0
HFD1_k127_5660573_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 404.0
HFD1_k127_5660573_1 Septum formation initiator K05589 - - 0.0000002081 63.0
HFD1_k127_5660573_2 PEGA domain - - - 0.00003539 56.0
HFD1_k127_5662087_0 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000049 192.0
HFD1_k127_5665938_0 - - - - 0.0000000000000006108 89.0
HFD1_k127_5665938_1 alpha-galactosidase K07407 GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0007275,GO:0008150,GO:0009505,GO:0009605,GO:0009607,GO:0009620,GO:0009653,GO:0009909,GO:0009911,GO:0009965,GO:0010016,GO:0015925,GO:0016787,GO:0016798,GO:0030312,GO:0032501,GO:0032502,GO:0043207,GO:0044464,GO:0048046,GO:0048366,GO:0048367,GO:0048518,GO:0048580,GO:0048582,GO:0048731,GO:0048827,GO:0048831,GO:0048856,GO:0050789,GO:0050793,GO:0050896,GO:0051094,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0065007,GO:0071944,GO:0099402,GO:1905392,GO:2000026,GO:2000241,GO:2000243 3.2.1.22 0.000000000000079 81.0
HFD1_k127_5665938_2 PFAM blue (type 1) copper domain protein K00728 - 2.4.1.109 0.0000000000001162 82.0
HFD1_k127_5665938_3 PFAM carbonic anhydrase - - - 0.00001449 54.0
HFD1_k127_5667500_0 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 496.0
HFD1_k127_5667500_1 - K02450,K03112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003012 283.0
HFD1_k127_5667500_2 - - - - 0.000000000000000000000000000000000000000000147 165.0
HFD1_k127_5667500_3 SEC-C motif - - - 0.0000000000000000000001414 107.0
HFD1_k127_5667500_4 AAA domain - - - 0.0000000000000002457 87.0
HFD1_k127_5672591_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000001718 175.0
HFD1_k127_5672591_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000008022 70.0
HFD1_k127_5673830_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001614 250.0
HFD1_k127_5673830_1 Histidine kinase - - - 0.00001849 57.0
HFD1_k127_5674509_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000006198 218.0
HFD1_k127_5674509_1 aminotransferase class I and II - - - 0.0000000000000000000000000003196 117.0
HFD1_k127_5674509_2 Aldehyde dehydrogenase - - - 0.0000000006852 71.0
HFD1_k127_5681985_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 487.0
HFD1_k127_5681985_1 COG1051 ADP-ribose pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000003639 228.0
HFD1_k127_5681985_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000004982 183.0
HFD1_k127_5682313_0 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 496.0
HFD1_k127_5682858_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 598.0
HFD1_k127_5682858_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001252 280.0
HFD1_k127_5682858_2 Thioesterase K07107 - - 0.000000000000000000000000000000000000004804 159.0
HFD1_k127_5684806_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000001252 196.0
HFD1_k127_5684806_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000001162 199.0
HFD1_k127_5685668_0 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004511 265.0
HFD1_k127_5685668_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001346 274.0
HFD1_k127_5685668_2 PFAM Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000001041 241.0
HFD1_k127_5685668_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000001143 202.0
HFD1_k127_5685668_4 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000002699 159.0
HFD1_k127_5685668_5 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000001326 106.0
HFD1_k127_5685807_0 Peptidase, M28 - - - 0.000000000001542 72.0
HFD1_k127_5686452_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 372.0
HFD1_k127_5686452_1 Cytochrome c K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000003892 241.0
HFD1_k127_5686452_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000002527 232.0
HFD1_k127_5688261_0 Chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 477.0
HFD1_k127_5688261_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 301.0
HFD1_k127_5688261_2 Type II secretory pathway, pseudopilin - - - 0.0000000000000000000000000000000000000000000000006354 183.0
HFD1_k127_5688261_3 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000004326 169.0
HFD1_k127_5688261_4 prepilin-type N-terminal cleavage methylation K02456 - - 0.000000000000001004 77.0
HFD1_k127_5690714_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000004655 173.0
HFD1_k127_5690714_1 - - - - 0.00000000003727 70.0
HFD1_k127_5695630_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 361.0
HFD1_k127_5698115_0 - - - - 0.000000000000000000000000000000000000000000000003311 181.0
HFD1_k127_5698115_1 Belongs to the malate synthase family K01638 - 2.3.3.9 0.0000000000000000000005397 98.0
HFD1_k127_5699065_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1047.0
HFD1_k127_5699065_1 Yip1 domain - - - 0.0000000001453 70.0
HFD1_k127_5701120_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 610.0
HFD1_k127_5703853_0 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000009231 106.0
HFD1_k127_5703853_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000001108 79.0
HFD1_k127_5703853_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000007758 88.0
HFD1_k127_5710290_0 efflux transmembrane transporter activity - - - 2.511e-197 641.0
HFD1_k127_5710290_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 420.0
HFD1_k127_5710290_2 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000005589 149.0
HFD1_k127_5714612_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000002057 239.0
HFD1_k127_5714612_1 Protein of unknown function (DUF3618) - - - 0.00000000000000000002333 96.0
HFD1_k127_5714612_2 DDE superfamily endonuclease - - - 0.000005818 56.0
HFD1_k127_5715278_0 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005408 276.0
HFD1_k127_5715278_1 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000003536 151.0
HFD1_k127_5715825_0 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002854 244.0
HFD1_k127_5715825_1 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000003233 134.0
HFD1_k127_5715994_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 412.0
HFD1_k127_5715994_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000001541 213.0
HFD1_k127_5719188_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 1.148e-294 928.0
HFD1_k127_5719188_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 9.486e-240 756.0
HFD1_k127_5719188_2 Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000008781 242.0
HFD1_k127_5719188_3 Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000001083 166.0
HFD1_k127_5719188_4 COG1881 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000005602 165.0
HFD1_k127_5719188_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000005092 72.0
HFD1_k127_5719188_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000008851 56.0
HFD1_k127_5719188_7 Thioesterase superfamily - - - 0.00000009774 59.0
HFD1_k127_5719188_8 Glycosyl hydrolase family 65 central catalytic domain - - - 0.000004674 53.0
HFD1_k127_5722470_0 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 569.0
HFD1_k127_5722470_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 392.0
HFD1_k127_5723231_0 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 419.0
HFD1_k127_5723231_1 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 375.0
HFD1_k127_5723231_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002217 256.0
HFD1_k127_5723231_3 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000000009527 208.0
HFD1_k127_5723231_4 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000001475 189.0
HFD1_k127_5723231_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000005192 153.0
HFD1_k127_5723231_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000002424 91.0
HFD1_k127_5723231_7 Serine aminopeptidase, S33 - - - 0.0000000000000142 78.0
HFD1_k127_5724334_0 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000009215 107.0
HFD1_k127_5724334_1 Transposase - - - 0.0000000003755 63.0
HFD1_k127_5724334_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000007375 65.0
HFD1_k127_5724334_3 ribonuclease activity - GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.0000000786 59.0
HFD1_k127_5725547_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 521.0
HFD1_k127_5725547_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 421.0
HFD1_k127_5725547_2 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 402.0
HFD1_k127_5725547_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000359 289.0
HFD1_k127_5725547_4 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007354 284.0
HFD1_k127_5725547_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003295 288.0
HFD1_k127_5725547_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000001775 51.0
HFD1_k127_5726808_0 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 327.0
HFD1_k127_5726808_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000007525 197.0
HFD1_k127_5726808_2 Transcriptional regulator - - - 0.0000000001013 64.0
HFD1_k127_5727373_0 - - - - 0.0000000305 66.0
HFD1_k127_5727810_0 response regulator K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 422.0
HFD1_k127_5727810_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001026 284.0
HFD1_k127_5727810_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000238 238.0
HFD1_k127_5727810_3 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.00000000000000000000000000000000000000000000000008641 186.0
HFD1_k127_5727810_4 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000001498 161.0
HFD1_k127_5727810_5 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000007639 139.0
HFD1_k127_5727810_6 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00000000000000000000000002201 112.0
HFD1_k127_5727810_7 pilus assembly protein PilW - - - 0.0000009178 61.0
HFD1_k127_5727810_8 Type II secretion system (T2SS), protein G K02456 - - 0.0003206 49.0
HFD1_k127_5728783_0 Prolyl oligopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 240.0
HFD1_k127_5728783_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000002754 133.0
HFD1_k127_5729632_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 414.0
HFD1_k127_5729632_1 Elongator protein 3, MiaB family, Radical SAM K22226,K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 306.0
HFD1_k127_5731132_0 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 525.0
HFD1_k127_5737710_0 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007009 277.0
HFD1_k127_5737710_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000001837 172.0
HFD1_k127_5739958_0 Domain of unknown function (DUF5118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001576 294.0
HFD1_k127_5739958_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003636 248.0
HFD1_k127_5739958_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001526 220.0
HFD1_k127_5739958_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000003569 152.0
HFD1_k127_5740690_0 creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000002531 192.0
HFD1_k127_5741410_0 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000004939 179.0
HFD1_k127_5741410_1 - - - - 0.000000000005588 72.0
HFD1_k127_5741893_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 488.0
HFD1_k127_5745963_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 473.0
HFD1_k127_5745963_1 Transposase, Mutator family - - - 0.000000000000000000000001142 104.0
HFD1_k127_5745963_2 Lsr2 - - - 0.000000000001612 76.0
HFD1_k127_5745963_3 Lsr2 - GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009628,GO:0009636,GO:0009889,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031668,GO:0033554,GO:0034641,GO:0040007,GO:0042221,GO:0042262,GO:0042493,GO:0042542,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000006978 48.0
HFD1_k127_5747772_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 287.0
HFD1_k127_5747772_1 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000002855 136.0
HFD1_k127_5747772_2 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000000000001037 100.0
HFD1_k127_5747772_3 Domain of unknown function (DUF4396) - - - 0.000000000003005 66.0
HFD1_k127_5748604_0 Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002639 269.0
HFD1_k127_5748604_1 iron dependent repressor - - - 0.0000000000000000000000000000000000000000000000000004554 190.0
HFD1_k127_5748604_2 Group II intron, maturase-specific domain - - - 0.000000000000003412 77.0
HFD1_k127_5754728_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.487e-263 819.0
HFD1_k127_5754728_1 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 333.0
HFD1_k127_5755626_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 452.0
HFD1_k127_5755626_1 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 382.0
HFD1_k127_5755626_2 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000008406 209.0
HFD1_k127_5755626_3 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000009613 165.0
HFD1_k127_5755626_4 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000006974 149.0
HFD1_k127_5755626_5 helicase K03580 - - 0.000002859 60.0
HFD1_k127_5756672_0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003512 256.0
HFD1_k127_5756672_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004348 252.0
HFD1_k127_5756672_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000001611 239.0
HFD1_k127_5756672_3 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000003576 164.0
HFD1_k127_5756672_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000641 151.0
HFD1_k127_5756672_5 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000005097 143.0
HFD1_k127_5756672_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000006396 131.0
HFD1_k127_5756672_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000003255 98.0
HFD1_k127_5756672_8 Ribosomal protein L30p/L7e K02907 - - 0.0000000000001745 75.0
HFD1_k127_5757680_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 372.0
HFD1_k127_5757680_1 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000006125 183.0
HFD1_k127_5757680_2 Tetratricopeptide repeat - - - 0.0005734 46.0
HFD1_k127_5760834_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001438 268.0
HFD1_k127_5760981_0 Small subunit K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 436.0
HFD1_k127_5760981_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 346.0
HFD1_k127_5762694_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 411.0
HFD1_k127_5762694_1 Protein of unknown function (DUF498/DUF598) - - - 0.000000004561 58.0
HFD1_k127_5767241_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 490.0
HFD1_k127_5767241_1 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 339.0
HFD1_k127_5767241_2 Anthranilate synthase K01665 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001524 284.0
HFD1_k127_5767241_3 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000001605 88.0
HFD1_k127_5770596_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 325.0
HFD1_k127_5770596_1 - - - - 0.00000000000000000000000000001149 133.0
HFD1_k127_5776895_0 Pfam:SusD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 394.0
HFD1_k127_5776895_1 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000008283 186.0
HFD1_k127_5776895_2 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000005533 150.0
HFD1_k127_5776895_3 Domain of unknown function (DUF4397) - - - 0.00000000000000000000000000000000959 139.0
HFD1_k127_5776895_4 - - - - 0.0000000000001215 82.0
HFD1_k127_5777336_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 412.0
HFD1_k127_5777336_1 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000006571 183.0
HFD1_k127_5777336_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000008309 147.0
HFD1_k127_5777336_3 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000001648 123.0
HFD1_k127_5780801_0 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 429.0
HFD1_k127_5780801_1 Domain of unknown function (DUF3536) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 348.0
HFD1_k127_5780801_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000003339 207.0
HFD1_k127_5788585_0 Serine hydrolase (FSH1) - - - 0.0000000000000000000000000000000000000000000000003658 189.0
HFD1_k127_5788585_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000006528 175.0
HFD1_k127_5788585_2 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.000000000000000000000007733 106.0
HFD1_k127_5790986_0 lysine biosynthetic process via aminoadipic acid - - - 2.341e-240 777.0
HFD1_k127_5790986_1 Domain of unknown function (DUF3471) K06889 - - 0.000000000000000000000000000000000000000000000000000000000000009836 224.0
HFD1_k127_5790986_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000001395 185.0
HFD1_k127_5798381_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 374.0
HFD1_k127_5798381_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000002192 108.0
HFD1_k127_5798436_0 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003896 286.0
HFD1_k127_5798436_1 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000005138 231.0
HFD1_k127_5798436_2 UvrB/uvrC motif K19411 - - 0.0000000000000000000000000000000000001291 156.0
HFD1_k127_5817280_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001561 255.0
HFD1_k127_5823013_0 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 397.0
HFD1_k127_5825867_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000004226 214.0
HFD1_k127_5827243_0 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 381.0
HFD1_k127_5827243_1 HAD-hyrolase-like K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000002833 200.0
HFD1_k127_5827243_2 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000003661 181.0
HFD1_k127_5827243_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.00000000000000000000000000000000000004092 151.0
HFD1_k127_5827243_4 DNA restriction-modification system - - - 0.00000000000000000000000006689 118.0
HFD1_k127_58282_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1581.0
HFD1_k127_58282_1 UDP binding domain K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 593.0
HFD1_k127_58282_10 Nad-dependent epimerase dehydratase K15856,K22252 - 1.1.1.135,1.1.1.281 0.000000000000000000000000000000001944 141.0
HFD1_k127_58282_11 Outer membrane lipoprotein K05807 - - 0.00000000000000000000000000000001154 138.0
HFD1_k127_58282_12 TPR repeat - - - 0.0000000000000000000000000003532 124.0
HFD1_k127_58282_2 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 587.0
HFD1_k127_58282_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 511.0
HFD1_k127_58282_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 487.0
HFD1_k127_58282_5 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 323.0
HFD1_k127_58282_6 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 302.0
HFD1_k127_58282_7 O-acyltransferase activity K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000002801 276.0
HFD1_k127_58282_8 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000001052 247.0
HFD1_k127_58282_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000005001 148.0
HFD1_k127_582858_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 396.0
HFD1_k127_582858_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 337.0
HFD1_k127_582858_2 Protein conserved in bacteria K09984 - - 0.0000000000000000000000000000000000000003891 151.0
HFD1_k127_582858_3 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000006391 152.0
HFD1_k127_582858_4 TPM domain K06872 - - 0.000002496 60.0
HFD1_k127_5833293_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 598.0
HFD1_k127_5833293_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 525.0
HFD1_k127_5833293_2 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001182 258.0
HFD1_k127_5833293_3 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000002577 173.0
HFD1_k127_5833293_4 GYD domain - - - 0.0000000000000000000000000000000000001048 145.0
HFD1_k127_5833293_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000007286 109.0
HFD1_k127_5833293_6 IMP dehydrogenase activity K07182 - - 0.000000000007915 72.0
HFD1_k127_5833293_7 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000008828 63.0
HFD1_k127_5838128_0 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000002576 208.0
HFD1_k127_5838128_1 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000773 166.0
HFD1_k127_5840740_0 Putative transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 594.0
HFD1_k127_5840740_1 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 317.0
HFD1_k127_5845551_0 membrane organization - - - 1.902e-217 708.0
HFD1_k127_5845551_1 protein kinase activity - - - 0.0000000000000000000000000000000000003716 143.0
HFD1_k127_5845551_2 Domain of unknown function (DUF4956) - - - 0.0000000000000000000000004729 117.0
HFD1_k127_5856158_0 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 466.0
HFD1_k127_5856158_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 355.0
HFD1_k127_5856158_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000004705 92.0
HFD1_k127_5856158_11 F5/8 type C domain - - - 0.0008309 53.0
HFD1_k127_5856158_2 PFAM Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 326.0
HFD1_k127_5856158_3 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001679 311.0
HFD1_k127_5856158_4 PFAM IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008046 251.0
HFD1_k127_5856158_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002078 259.0
HFD1_k127_5856158_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000001021 228.0
HFD1_k127_5856158_7 Epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000002455 211.0
HFD1_k127_5856158_8 TIGRFAM polymorphic outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000001184 223.0
HFD1_k127_5856158_9 Metallo-peptidase family M12 - - - 0.00000000000000000000000000001755 138.0
HFD1_k127_5856678_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 555.0
HFD1_k127_5858108_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 498.0
HFD1_k127_5858108_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003623 256.0
HFD1_k127_5858108_2 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000006318 90.0
HFD1_k127_5860764_0 Transposase and inactivated derivatives - - - 6.946e-258 803.0
HFD1_k127_5860764_1 insertion sequence ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 377.0
HFD1_k127_5860764_2 Transposase - - - 0.00000000000000000000000005554 108.0
HFD1_k127_5860764_3 Transposase - - - 0.000000000002308 66.0
HFD1_k127_5864429_0 - - - - 0.000000000000000000000007245 107.0
HFD1_k127_5864429_1 - - - - 0.000001735 54.0
HFD1_k127_5864429_2 - - - - 0.00001912 52.0
HFD1_k127_5865076_0 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
HFD1_k127_5866289_0 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000001282 91.0
HFD1_k127_5868131_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 598.0
HFD1_k127_5868131_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000005047 173.0
HFD1_k127_5871906_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 342.0
HFD1_k127_5871906_1 HNH endonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000007343 130.0
HFD1_k127_5871906_2 - - - - 0.00000000000000000007335 93.0
HFD1_k127_5871906_3 PFAM Transposase IS3 K07483 - - 0.00000000000000000008704 104.0
HFD1_k127_5877300_0 PFAM Glycosyl transferase family 2 - - - 9.189e-246 776.0
HFD1_k127_5881020_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 411.0
HFD1_k127_5881020_1 Pyridine nucleotide-disulphide oxidoreductase K21567 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 383.0
HFD1_k127_5881020_2 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001786 271.0
HFD1_k127_5881020_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000005721 148.0
HFD1_k127_5884183_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 297.0
HFD1_k127_5884183_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000003659 156.0
HFD1_k127_5890867_0 PFAM transposase, IS4 family protein - - - 0.000000001003 68.0
HFD1_k127_5902495_0 Aldehyde dehydrogenase family K22187 - - 4.479e-263 816.0
HFD1_k127_5902495_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 596.0
HFD1_k127_5902495_2 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000004178 251.0
HFD1_k127_5902495_3 - - - - 0.0000000000000009582 91.0
HFD1_k127_5902495_4 efflux transmembrane transporter activity - - - 0.0000000000006877 82.0
HFD1_k127_5902495_5 - - - - 0.0000001096 60.0
HFD1_k127_5903275_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000004686 167.0
HFD1_k127_5903275_1 Autotransporter beta-domain - - - 0.00000000004922 72.0
HFD1_k127_5905043_0 O-Antigen ligase - - - 0.000000000000000000000000000000000000035 162.0
HFD1_k127_5905043_1 Deoxynucleoside kinase - - - 0.000001894 53.0
HFD1_k127_5906011_0 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001236 293.0
HFD1_k127_5906011_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000003387 156.0
HFD1_k127_5906011_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001956 147.0
HFD1_k127_5908207_0 Leishmanolysin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002164 256.0
HFD1_k127_5918114_0 PFAM transposase IS66 - - - 1.139e-255 798.0
HFD1_k127_5918114_1 Transposase IS4 family - - - 1.027e-212 670.0
HFD1_k127_5918114_2 PFAM transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 340.0
HFD1_k127_5918114_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001188 246.0
HFD1_k127_5918114_4 Transposase K07483 - - 0.00000000009229 64.0
HFD1_k127_592811_0 Divalent cation transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 377.0
HFD1_k127_592811_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 313.0
HFD1_k127_5940856_1 PFAM biotin lipoyl attachment domain-containing protein K00382 - 1.8.1.4 0.000000000000000000000000003367 110.0
HFD1_k127_5941511_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 312.0
HFD1_k127_5941511_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000001979 145.0
HFD1_k127_5945905_0 extracellular polysaccharide biosynthetic process K16554,K16692 - - 0.0000000000000000006895 99.0
HFD1_k127_5953139_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 392.0
HFD1_k127_5953139_1 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000000000000000003556 197.0
HFD1_k127_5957131_0 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 306.0
HFD1_k127_5957131_1 Integrase core domain - - - 0.0000000000000000000000000000000001144 135.0
HFD1_k127_5957131_2 Transposase - - - 0.0000000000000007035 78.0
HFD1_k127_5963549_0 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 372.0
HFD1_k127_5963549_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000003705 265.0
HFD1_k127_5963549_2 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000002387 246.0
HFD1_k127_5963549_3 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000001145 241.0
HFD1_k127_5963549_4 Mazg nucleotide pyrophosphohydrolase K00800 - 2.5.1.19 0.00000000000000000000000000000000000000009196 153.0
HFD1_k127_5963549_5 - - - - 0.00000008285 55.0
HFD1_k127_5978481_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 302.0
HFD1_k127_5978481_1 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000003459 121.0
HFD1_k127_59792_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 407.0
HFD1_k127_59792_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 391.0
HFD1_k127_59792_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000008236 209.0
HFD1_k127_59792_3 Short-chain dehydrogenase reductase SDR K00059,K11610 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0018454,GO:0019752,GO:0030497,GO:0032787,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046459,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000005464 185.0
HFD1_k127_59792_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000002539 169.0
HFD1_k127_59792_5 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000004766 93.0
HFD1_k127_5988734_0 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000001135 201.0
HFD1_k127_5988734_1 pfam abc K06857 - 3.6.3.55 0.000000000000000000000000000000000000007652 156.0
HFD1_k127_5988734_2 - - - - 0.0000000000002572 79.0
HFD1_k127_5988734_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 0.00001483 47.0
HFD1_k127_5995002_0 Cluster 0025 8 SCAB3371, SCAB4481, SCAB7601, SCAB11701, SCAB20281, SCAB40511, SCAB68181 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 334.0
HFD1_k127_5995002_1 Evidence 2b Function of strongly homologous gene K07497 - - 0.0000000000000000000000000000000000000000000000000000000000002324 215.0
HFD1_k127_5995002_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000005666 169.0
HFD1_k127_599639_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 6.808e-266 842.0
HFD1_k127_599639_1 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000000001947 213.0
HFD1_k127_599639_2 Amino acid permease K03294 - - 0.0000000000000000000000000005556 125.0
HFD1_k127_599639_3 DALR_2 K01883 - 6.1.1.16 0.00000000000000000000000003966 111.0
HFD1_k127_5997036_0 FAD binding domain K09828 - 1.3.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 591.0
HFD1_k127_5997036_1 - - - - 0.000000000000000000000000000000000053 156.0
HFD1_k127_6002750_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 348.0
HFD1_k127_6002750_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000003751 231.0
HFD1_k127_6005297_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 300.0
HFD1_k127_6005297_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000001282 111.0
HFD1_k127_6007450_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 294.0
HFD1_k127_6007450_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000007698 182.0
HFD1_k127_6008316_0 PFAM extracellular solute-binding protein family 1 K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 314.0
HFD1_k127_6008316_1 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000003694 61.0
HFD1_k127_6010694_0 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000003637 166.0
HFD1_k127_6010694_1 Domain of unknown function (DUF3943) - - - 0.0000000000000000000001198 108.0
HFD1_k127_6018603_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003012 253.0
HFD1_k127_6018603_1 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000538 177.0
HFD1_k127_60221_0 Transposase and inactivated derivatives IS30 family - - - 9.637e-211 667.0
HFD1_k127_60221_1 Integrase core domain - - - 0.00000000000000000000006984 106.0
HFD1_k127_60221_2 Belongs to the 'phage' integrase family - - - 0.00000000000444 68.0
HFD1_k127_6027178_0 phosphorelay signal transduction system K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 409.0
HFD1_k127_6027178_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000006725 119.0
HFD1_k127_6027178_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000002259 118.0
HFD1_k127_6027178_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000008515 75.0
HFD1_k127_6052360_0 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000007904 194.0
HFD1_k127_6052360_1 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000228 158.0
HFD1_k127_6059457_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 554.0
HFD1_k127_6059457_1 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000006664 256.0
HFD1_k127_6082972_0 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 332.0
HFD1_k127_6082972_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 317.0
HFD1_k127_6084811_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 1.828e-194 623.0
HFD1_k127_6084811_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002811 254.0
HFD1_k127_6084811_2 Transcriptional regulator K03710,K07978,K07979 - - 0.000000000000000000000005598 108.0
HFD1_k127_6084811_3 reverse transcriptase - - - 0.000002056 54.0
HFD1_k127_6084811_4 cAMP biosynthetic process - - - 0.000002702 50.0
HFD1_k127_6092607_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 370.0
HFD1_k127_6092607_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 347.0
HFD1_k127_6092607_2 B3/4 domain K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 342.0
HFD1_k127_6092607_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000002201 241.0
HFD1_k127_6092607_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000004488 171.0
HFD1_k127_6092607_5 arginine K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000002273 166.0
HFD1_k127_6092607_6 Ribosomal protein L35 K02916 - - 0.000000001061 64.0
HFD1_k127_6099665_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 390.0
HFD1_k127_6099665_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 373.0
HFD1_k127_6099813_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 348.0
HFD1_k127_6099813_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
HFD1_k127_6099813_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002452 221.0
HFD1_k127_6104297_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 415.0
HFD1_k127_6129497_0 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 477.0
HFD1_k127_6131248_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 359.0
HFD1_k127_6131248_1 - - - - 0.00000000000000000000000000002774 125.0
HFD1_k127_6131248_2 Response regulator, receiver K02487,K03407,K06596 - 2.7.13.3 0.0004455 46.0
HFD1_k127_6131804_0 ERAP1-like C-terminal domain K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 608.0
HFD1_k127_6139196_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 556.0
HFD1_k127_6146135_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 349.0
HFD1_k127_6146135_1 Transposase - - - 0.0000000002828 68.0
HFD1_k127_6150071_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 400.0
HFD1_k127_6150071_1 Methyltransferase FkbM domain - - - 0.0000000000000000002962 99.0
HFD1_k127_6157688_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 415.0
HFD1_k127_6157688_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 409.0
HFD1_k127_6157688_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000007185 120.0
HFD1_k127_6175985_0 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 443.0
HFD1_k127_6175985_1 transferase activity, transferring glycosyl groups - - - 0.000000000005501 69.0
HFD1_k127_6178009_0 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000004257 235.0
HFD1_k127_6178009_1 Spore coat protein K00973 - 2.7.7.24 0.00004286 49.0
HFD1_k127_6178712_0 E1-E2 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 338.0
HFD1_k127_6180008_0 HypF finger K04656 - - 1.226e-307 959.0
HFD1_k127_6180008_1 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 317.0
HFD1_k127_6180008_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000001198 117.0
HFD1_k127_6180008_3 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000001466 112.0
HFD1_k127_6180008_4 - - - - 0.00005272 48.0
HFD1_k127_6190652_0 Aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 440.0
HFD1_k127_6190652_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 429.0
HFD1_k127_6190652_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000001827 180.0
HFD1_k127_6191868_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002215 266.0
HFD1_k127_6191868_1 Sugar (and other) transporter - - - 0.0000000004876 68.0
HFD1_k127_6197566_0 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000009412 194.0
HFD1_k127_6197566_1 Tetratricopeptide repeats - - - 0.000002364 59.0
HFD1_k127_6198943_0 DDE_Tnp_1-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 505.0
HFD1_k127_6201588_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000002807 188.0
HFD1_k127_6201588_1 - - - - 0.0000000000000000000000000000000001364 139.0
HFD1_k127_6201588_2 Metallopeptidase family M24 - - - 0.00000000000000000000000000215 115.0
HFD1_k127_6201588_3 Putative zinc-finger - - - 0.00000000000001797 77.0
HFD1_k127_6221859_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000517 210.0
HFD1_k127_6221859_1 Peptidase m28 - - - 0.00000000000000000000000000000000000000000000000002434 183.0
HFD1_k127_623213_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 325.0
HFD1_k127_6232931_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 327.0
HFD1_k127_6232931_1 IS66 Orf2 like protein K07484 - - 0.000000000000000000000000000000000000000000000000000000000001136 218.0
HFD1_k127_6232931_2 Transposase K07483 - - 0.0000000000000000000000000003794 118.0
HFD1_k127_6237118_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000104 285.0
HFD1_k127_6246555_0 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000001305 259.0
HFD1_k127_62492_0 - - - - 0.00000000000000000000000000000000001121 151.0
HFD1_k127_62492_1 PFAM secretion protein HlyD family protein - - - 0.000000057 66.0
HFD1_k127_6256188_0 FAD linked oxidase domain protein - - - 5.313e-235 737.0
HFD1_k127_6257073_0 HTH-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 467.0
HFD1_k127_6257073_1 PFAM transposase IS3 IS911 family protein K07483 - - 0.00000000000000000000000000000000000000000000119 167.0
HFD1_k127_6257073_2 Fibronectin type III-like domain K05349 - 3.2.1.21 0.000000000000000000000000003207 116.0
HFD1_k127_6257073_3 PFAM PKD domain containing protein - - - 0.00000000002726 66.0
HFD1_k127_6271530_0 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000003122 123.0
HFD1_k127_6281880_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000005777 166.0
HFD1_k127_6281880_1 PFAM Membrane protein of K08972 - - 0.00000000000000000000000006683 118.0
HFD1_k127_6281880_2 Protein of unknown function (DUF423) - - - 0.00000000000000005213 91.0
HFD1_k127_6308135_0 molybdenum ion binding K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 292.0
HFD1_k127_6308135_1 AraC-like ligand binding domain - - - 0.00000001747 56.0
HFD1_k127_6318655_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0 1127.0
HFD1_k127_6318655_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 385.0
HFD1_k127_6318655_2 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000001077 227.0
HFD1_k127_6329121_0 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 406.0
HFD1_k127_6329121_1 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005877 272.0
HFD1_k127_6329121_2 UPF0126 domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000003744 141.0
HFD1_k127_6329121_3 Oligoendopeptidase f - - - 0.0000004799 63.0
HFD1_k127_6332089_0 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 294.0
HFD1_k127_6332089_1 - - - - 0.0000000000000000000000000000000000000000000000009629 184.0
HFD1_k127_6332089_2 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000002896 175.0
HFD1_k127_6332089_3 - - - - 0.000000000000000000008788 106.0
HFD1_k127_6344974_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 341.0
HFD1_k127_6344974_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.000000000003918 78.0
HFD1_k127_6387773_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 287.0
HFD1_k127_6387773_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000002886 202.0
HFD1_k127_6387773_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001447 156.0
HFD1_k127_6387773_3 DNA polymerase X K02347 - - 0.0000000001079 63.0
HFD1_k127_639581_0 Amidohydrolase family K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 501.0
HFD1_k127_639581_1 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.00000000000000001236 82.0
HFD1_k127_641745_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 454.0
HFD1_k127_6431338_0 Peptidase family M1 domain K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000007119 253.0
HFD1_k127_6431448_0 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 455.0
HFD1_k127_6431448_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 312.0
HFD1_k127_6431448_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000008054 255.0
HFD1_k127_6431448_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000007922 241.0
HFD1_k127_6431448_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000003566 198.0
HFD1_k127_6432579_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.0 1048.0
HFD1_k127_6432579_1 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 1.31e-270 850.0
HFD1_k127_6432579_2 Belongs to the GcvT family K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 448.0
HFD1_k127_6434060_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 336.0
HFD1_k127_6434060_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000001494 217.0
HFD1_k127_6434060_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00002557 46.0
HFD1_k127_6437448_0 Modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 317.0
HFD1_k127_6437448_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000008295 88.0
HFD1_k127_6439618_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 289.0
HFD1_k127_6439618_1 GMC oxidoreductase K00108 - 1.1.99.1 0.00000000000000000000000000000000000004365 143.0
HFD1_k127_6441855_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 456.0
HFD1_k127_6441855_1 Sodium:dicarboxylate symporter family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 381.0
HFD1_k127_6441855_2 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.000000000000000000000000000000000000001463 160.0
HFD1_k127_6441855_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000009319 131.0
HFD1_k127_6441855_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000005086 87.0
HFD1_k127_6441855_5 Ribonuclease B OB domain K03704 - - 0.00000000000008366 75.0
HFD1_k127_6441855_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000007546 63.0
HFD1_k127_6444761_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000002628 204.0
HFD1_k127_6444761_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000001506 169.0
HFD1_k127_6444761_2 - - - - 0.00000000000000000000000000000006981 140.0
HFD1_k127_6446055_0 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000000000000000000000000000000000000000000000000009631 202.0
HFD1_k127_6446055_1 Transposase - - - 0.000000000000000000000000000000437 127.0
HFD1_k127_6448465_0 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 388.0
HFD1_k127_6448465_1 of the major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001147 266.0
HFD1_k127_6448465_2 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000002454 119.0
HFD1_k127_6448465_3 Limonene-1,2-epoxide hydrolase catalytic domain K06893 - - 0.00005763 55.0
HFD1_k127_6449545_0 ATP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006591 291.0
HFD1_k127_6449545_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000005214 132.0
HFD1_k127_6453324_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 574.0
HFD1_k127_6457042_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 592.0
HFD1_k127_6457042_1 N,N-dimethylaniline monooxygenase activity K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 481.0
HFD1_k127_6457042_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 412.0
HFD1_k127_6457042_3 Protein of unknown function (DUF2167) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000146 280.0
HFD1_k127_6457042_4 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000003651 218.0
HFD1_k127_6457042_5 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000002937 198.0
HFD1_k127_6461444_0 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 374.0
HFD1_k127_6461444_1 Tetratricopeptide repeat - - - 0.000000000000001047 88.0
HFD1_k127_6461444_2 protein secretion K03116 GO:0008150,GO:0040007 - 0.0000000005971 63.0
HFD1_k127_6461456_0 Nucleoside H+ symporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 561.0
HFD1_k127_6461456_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 449.0
HFD1_k127_6461456_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000122 247.0
HFD1_k127_6461456_3 acetyltransferase - - - 0.00000000000000000000000000000000000000004915 165.0
HFD1_k127_6461456_4 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000001921 147.0
HFD1_k127_6461456_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000136 50.0
HFD1_k127_6463014_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 361.0
HFD1_k127_6463014_1 - - - - 0.0000000000000001223 88.0
HFD1_k127_6463975_0 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000002161 173.0
HFD1_k127_6463975_1 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000002097 106.0
HFD1_k127_6464169_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.0 1166.0
HFD1_k127_6464169_1 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000002327 238.0
HFD1_k127_6464169_2 HAD-hyrolase-like - - - 0.00000000000000001483 90.0
HFD1_k127_6467661_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 308.0
HFD1_k127_6467954_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000003784 228.0
HFD1_k127_6467954_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000002845 222.0
HFD1_k127_6467954_2 Cupin 2, conserved barrel domain protein - - - 0.0000000003037 66.0
HFD1_k127_6474942_0 TrkA-C domain K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 488.0
HFD1_k127_6478164_0 Involved in the tonB-independent uptake of proteins K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000006237 190.0
HFD1_k127_6478164_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000006669 177.0
HFD1_k127_6478164_2 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000003967 179.0
HFD1_k127_6481545_0 Major Facilitator K16211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001071 271.0
HFD1_k127_6481545_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000006569 196.0
HFD1_k127_6481951_0 PA14 domain K05349 - 3.2.1.21 0.0 1046.0
HFD1_k127_6481951_1 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002051 258.0
HFD1_k127_6481951_3 Transglycosylase associated protein - - - 0.00000000000000237 78.0
HFD1_k127_6481951_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000005419 57.0
HFD1_k127_6487181_0 Protein involved in DNA binding, transposase activity and DNA transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 510.0
HFD1_k127_6488102_0 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 377.0
HFD1_k127_6488102_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000007283 243.0
HFD1_k127_6488102_2 GGDEF domain' - - - 0.000000000000000000000000000004063 126.0
HFD1_k127_6489244_0 PFAM Integrase, catalytic core - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 592.0
HFD1_k127_6491497_0 PFAM SAF domain K02279 - - 0.00000000000000000000000000000000000000000001387 172.0
HFD1_k127_6491497_1 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000000000000000002932 107.0
HFD1_k127_6491497_2 TadE-like protein - - - 0.00000002374 64.0
HFD1_k127_6495217_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 375.0
HFD1_k127_6495217_1 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.00000000001714 68.0
HFD1_k127_6497049_0 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.00000000000000000000000000000000000000000000007245 182.0
HFD1_k127_6497049_1 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000557 56.0
HFD1_k127_6501625_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 584.0
HFD1_k127_6501625_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 385.0
HFD1_k127_6501625_2 redox protein regulator of disulfide bond formation K04063 - - 0.000000000000000000000000000000002998 134.0
HFD1_k127_6502149_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 392.0
HFD1_k127_6502149_1 Glycine oxidase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000003646 202.0
HFD1_k127_6502149_2 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000157 186.0
HFD1_k127_6502149_3 Glycosyl transferase family 2 K08301 - - 0.000000000000000000000000000000000000000000004325 182.0
HFD1_k127_6502149_4 - - - - 0.00000000000000000009855 91.0
HFD1_k127_6502149_5 - - - - 0.0000006023 54.0
HFD1_k127_6510330_0 peptidase - - - 0.000000000000000000000000000000000000003289 163.0
HFD1_k127_6517297_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000176 61.0
HFD1_k127_6525148_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 280.0
HFD1_k127_6525148_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008588 270.0
HFD1_k127_6525148_2 MacB-like periplasmic core domain K02004 - - 0.0000000000001082 78.0
HFD1_k127_6529519_0 Membrane dipeptidase (Peptidase family M19) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 394.0
HFD1_k127_6529519_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 314.0
HFD1_k127_6529519_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000003454 220.0
HFD1_k127_6529519_3 Tetratricopeptide repeat - - - 0.00000000001528 68.0
HFD1_k127_6529519_4 Sulfotransferase family - - - 0.0000000002224 74.0
HFD1_k127_6529625_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 394.0
HFD1_k127_6531560_0 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 420.0
HFD1_k127_6531560_1 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 353.0
HFD1_k127_6531560_2 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.000000000000000000000006865 105.0
HFD1_k127_6532266_0 Transposase or inactivated derivative - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 517.0
HFD1_k127_6535307_0 Transcriptional regulatory protein, C terminal - - - 0.0005064 52.0
HFD1_k127_6537581_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 538.0
HFD1_k127_6537704_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 333.0
HFD1_k127_6537704_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 288.0
HFD1_k127_6553042_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 529.0
HFD1_k127_6553042_1 Transposase and inactivated derivatives K07498,K18320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 360.0
HFD1_k127_6553042_2 Acyl-CoA dehydrogenase, middle domain - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000144 164.0
HFD1_k127_6557649_0 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000001257 164.0
HFD1_k127_6557649_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000003659 114.0
HFD1_k127_6557649_2 Dodecin K09165 - - 0.0000000000000000003396 95.0
HFD1_k127_6574702_0 - - - - 0.0000000000000000000000002813 122.0
HFD1_k127_6574702_1 PFAM glycoside hydrolase family 13 domain protein - - - 0.000000000000000000004975 95.0
HFD1_k127_6574702_2 - - - - 0.00000000000819 76.0
HFD1_k127_6577633_0 PFAM Transposase K07485 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 9.319e-212 664.0
HFD1_k127_6577633_1 Activator of Hsp90 ATPase 1 family protein - - - 0.00000000001478 64.0
HFD1_k127_6584001_0 Domain of unknown function (DUF5118) - - - 1.792e-208 676.0
HFD1_k127_6584001_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 460.0
HFD1_k127_6584001_2 Predicted membrane protein (DUF2238) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
HFD1_k127_6587613_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 391.0
HFD1_k127_6587613_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000003789 173.0
HFD1_k127_6598179_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000006404 161.0
HFD1_k127_6598179_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000002147 85.0
HFD1_k127_6600556_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001032 277.0
HFD1_k127_6600556_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000328 64.0
HFD1_k127_6604542_0 - - - - 0.0000000000132 73.0
HFD1_k127_6604549_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 380.0
HFD1_k127_6604549_1 Protein of unknown function (DUF1565) - - - 0.00000000000000000005664 106.0
HFD1_k127_6609234_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000001722 205.0
HFD1_k127_6609234_1 PFAM Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000002259 86.0
HFD1_k127_6613421_0 Ankyrin repeats (3 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 487.0
HFD1_k127_6613421_1 Transcriptional regulator - - - 0.00000000000000000000000000000000001924 142.0
HFD1_k127_6616851_0 Transposase - - - 1.933e-283 877.0
HFD1_k127_6616851_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 405.0
HFD1_k127_6623301_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 397.0
HFD1_k127_6623301_1 Belongs to the ompA family K03640 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 - 0.000000000000000000000009992 113.0
HFD1_k127_6642051_0 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000544 222.0
HFD1_k127_6642051_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000005691 63.0
HFD1_k127_6645636_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 330.0
HFD1_k127_6651289_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 550.0
HFD1_k127_6652631_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 614.0
HFD1_k127_6652631_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000007941 210.0
HFD1_k127_6652631_2 Transposase - - - 0.000000000000000000000000000001199 123.0
HFD1_k127_6658038_0 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002208 300.0
HFD1_k127_6658038_1 endoribonuclease L-PSP - - - 0.0000000002416 72.0
HFD1_k127_6659832_0 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000001816 258.0
HFD1_k127_6659832_1 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000001762 150.0
HFD1_k127_6662164_0 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 282.0
HFD1_k127_6662164_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000002518 75.0
HFD1_k127_6664241_0 - - - - 1.109e-218 695.0
HFD1_k127_6664241_1 Domain of unknown function (DUF4118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 328.0
HFD1_k127_6666803_0 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 304.0
HFD1_k127_6666803_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000002219 201.0
HFD1_k127_6666803_2 Transcriptional K07979 - - 0.00000000000000000007956 93.0
HFD1_k127_6669188_0 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001585 268.0
HFD1_k127_6669188_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008839 260.0
HFD1_k127_6669188_2 Transposase - - - 0.00000000000000000000000000000000000000000000000000000001298 203.0
HFD1_k127_6669188_3 Transposase - - - 0.00000000000000000000000000000000000000000000000000000005607 206.0
HFD1_k127_6669188_4 Transposase - - - 0.00000000000000000000000000000000000000000000003932 177.0
HFD1_k127_6669188_5 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000004292 118.0
HFD1_k127_6669188_6 Pfam Integrase core domain - - - 0.0000000000000000008504 98.0
HFD1_k127_6669188_7 PFAM Transposase K07483 - - 0.00000000000004385 73.0
HFD1_k127_6669188_8 Integrase core domain - - - 0.000000003446 68.0
HFD1_k127_6669188_9 Transposase - - - 0.00000001377 61.0
HFD1_k127_6671931_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 425.0
HFD1_k127_6671931_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 359.0
HFD1_k127_6671931_10 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000006902 59.0
HFD1_k127_6671931_2 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007392 251.0
HFD1_k127_6671931_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000008152 213.0
HFD1_k127_6671931_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000002142 205.0
HFD1_k127_6671931_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000003155 201.0
HFD1_k127_6671931_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000009536 145.0
HFD1_k127_6671931_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000001327 141.0
HFD1_k127_6671931_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000002561 116.0
HFD1_k127_6671931_9 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000004055 98.0
HFD1_k127_6680994_0 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000001365 218.0
HFD1_k127_6680994_1 alginic acid biosynthetic process - - - 0.00000000000000000000000000000001038 139.0
HFD1_k127_6682567_0 PFAM Glycoside hydrolase, family 20, catalytic core K12373 - 3.2.1.52 1.593e-204 657.0
HFD1_k127_6682567_1 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000001943 210.0
HFD1_k127_6682567_2 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000004025 60.0
HFD1_k127_6684005_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 434.0
HFD1_k127_669924_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000005799 235.0
HFD1_k127_669924_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000002473 250.0
HFD1_k127_669924_2 Belongs to the peptidase S8 family - - - 0.000000000001358 82.0
HFD1_k127_6714856_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 487.0
HFD1_k127_6714856_1 Glutamine amidotransferase - - - 0.000000000000000000001403 96.0
HFD1_k127_6719153_0 cation efflux system protein (Heavy metal efflux pump) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 366.0
HFD1_k127_6721456_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 344.0
HFD1_k127_6721456_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000002137 75.0
HFD1_k127_6721456_2 amidohydrolase - - - 0.00000003294 65.0
HFD1_k127_6725761_0 Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 428.0
HFD1_k127_6730234_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000002557 233.0
HFD1_k127_6730234_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000122 48.0
HFD1_k127_6735608_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 342.0
HFD1_k127_6735744_0 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 446.0
HFD1_k127_6736929_0 Belongs to the peptidase S8 family - - - 0.0000000000000000003546 102.0
HFD1_k127_6739415_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 507.0
HFD1_k127_6739652_0 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 292.0
HFD1_k127_6739652_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000003507 197.0
HFD1_k127_6739652_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000004554 147.0
HFD1_k127_6742033_0 Protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000000000000000000000000000000000000003239 199.0
HFD1_k127_6742033_1 - - - - 0.000000000000000000000000000000002471 138.0
HFD1_k127_6742460_0 Transposase DDE domain K07492 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 317.0
HFD1_k127_6742460_1 helicase activity - - - 0.00000000000000000116 98.0
HFD1_k127_6745234_0 HTH-like domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002149 249.0
HFD1_k127_6745234_1 Transposase K07483 - - 0.0000000000000000000000000000000000009439 141.0
HFD1_k127_6751382_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004469 250.0
HFD1_k127_6751382_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001286 255.0
HFD1_k127_6751382_2 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000002406 76.0
HFD1_k127_6751382_3 Zinc finger domain - - - 0.00000000002944 69.0
HFD1_k127_6752041_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003359 267.0
HFD1_k127_6752041_1 - - - - 0.00000000000000000000000000000000000000004118 162.0
HFD1_k127_6752041_2 Helix-turn-helix domain - - - 0.000000000000000000000279 104.0
HFD1_k127_6756563_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1215.0
HFD1_k127_6763504_0 Hsp70 protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 594.0
HFD1_k127_6763504_1 rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000001062 192.0
HFD1_k127_6763504_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000005764 156.0
HFD1_k127_6763504_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000001045 130.0
HFD1_k127_6763504_4 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000001115 132.0
HFD1_k127_6763504_5 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000002181 63.0
HFD1_k127_6768504_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000003273 179.0
HFD1_k127_6768504_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000422 174.0
HFD1_k127_6768504_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000001135 162.0
HFD1_k127_6768504_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000006422 172.0
HFD1_k127_6768504_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000002135 153.0
HFD1_k127_6772568_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 426.0
HFD1_k127_6775961_0 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000008303 179.0
HFD1_k127_6775961_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000006188 168.0
HFD1_k127_6775961_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000001241 75.0
HFD1_k127_6794707_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 383.0
HFD1_k127_6794707_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000006862 150.0
HFD1_k127_6794707_2 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000003932 126.0
HFD1_k127_6794707_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000929 123.0
HFD1_k127_6796841_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 6.924e-210 660.0
HFD1_k127_6796841_1 mannose metabolic process - - - 0.00000000000000000008694 95.0
HFD1_k127_6800879_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000001032 98.0
HFD1_k127_6800879_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000007278 55.0
HFD1_k127_6805851_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 318.0
HFD1_k127_6805851_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000005372 166.0
HFD1_k127_6808278_0 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000001421 175.0
HFD1_k127_6808278_1 Putative lumazine-binding - - - 0.000000000000000000000000000000000004884 143.0
HFD1_k127_6808278_2 Thioesterase superfamily - - - 0.000000007223 59.0
HFD1_k127_6813643_0 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000002104 199.0
HFD1_k127_6813643_1 bacterial OsmY and nodulation domain - - - 0.0000000000000000000000000000000000000000702 160.0
HFD1_k127_6813643_2 nuclear chromosome segregation - - - 0.0000000000000000000000005535 117.0
HFD1_k127_6813643_3 Proline dehydrogenase K00318 - - 0.0000007406 56.0
HFD1_k127_6827234_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 593.0
HFD1_k127_6850278_0 protein kinase activity - - - 0.000000000000000000000000008871 122.0
HFD1_k127_6850278_1 Penicillinase repressor - - - 0.00000000000005562 72.0
HFD1_k127_6857998_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 370.0
HFD1_k127_6868154_0 Elongation factor G, domain IV K02355 - - 1.273e-235 742.0
HFD1_k127_6887148_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 355.0
HFD1_k127_6887148_1 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 298.0
HFD1_k127_6897851_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005161 291.0
HFD1_k127_6897851_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007973 273.0
HFD1_k127_6897851_2 - - - - 0.00000000000000000000000000000000000000000000000000000008451 203.0
HFD1_k127_6897851_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000001107 200.0
HFD1_k127_6897851_4 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000002164 97.0
HFD1_k127_6902823_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 392.0
HFD1_k127_69094_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000002748 236.0
HFD1_k127_69094_1 Transposase IS66 family K07484 - - 0.00000000000000000000000000000000106 138.0
HFD1_k127_69094_2 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000009402 126.0
HFD1_k127_6910727_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000119 273.0
HFD1_k127_6910727_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000004556 132.0
HFD1_k127_6930095_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 331.0
HFD1_k127_6930095_1 - - - - 0.0000000000000000000000000000000000005549 145.0
HFD1_k127_6938060_0 Thrombospondin type 3 repeat - - - 0.00000000000000000000000000000000000000000000000000000000003812 211.0
HFD1_k127_6938060_1 chlorophyll binding - - - 0.000000000000000000000000000000000000000002756 169.0
HFD1_k127_6943163_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 383.0
HFD1_k127_6943163_1 DinB family - - - 0.0000000000000000000000000000000000000000000002447 172.0
HFD1_k127_6943163_2 Response regulator receiver K02477 - - 0.00000005856 57.0
HFD1_k127_6943163_3 - - - - 0.000001864 56.0
HFD1_k127_6945980_0 - - - - 0.00000000000000172 89.0
HFD1_k127_6945980_1 COG0739 Membrane proteins related to metalloendopeptidases K19304 GO:0000270,GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008237,GO:0009987,GO:0012501,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564 - 0.0000000000004182 77.0
HFD1_k127_6987412_0 Peptidase M56 - - - 0.000000000000000000000002909 118.0
HFD1_k127_6987412_1 cytochrome oxidase assembly K02259 - - 0.0000156 51.0
HFD1_k127_6990232_0 Transposase domain (DUF772) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 462.0
HFD1_k127_7063142_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1163.0
HFD1_k127_7063142_1 PFAM regulator of chromosome condensation, RCC1 - - - 0.000002578 49.0
HFD1_k127_7068640_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000013 243.0
HFD1_k127_7068640_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000007243 93.0
HFD1_k127_7072908_0 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007086 290.0
HFD1_k127_7072908_1 Transposase - - - 0.00000000000001589 76.0
HFD1_k127_7091248_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 437.0
HFD1_k127_7091248_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000006209 181.0
HFD1_k127_7117273_0 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 312.0
HFD1_k127_7117273_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000002977 110.0
HFD1_k127_7117273_2 Virulence factor BrkB K07058 - - 0.00000000000000000000000004403 124.0
HFD1_k127_7117273_3 Threonine aldolase K01620 - 4.1.2.48 0.00001382 57.0
HFD1_k127_7152589_0 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 462.0
HFD1_k127_7158421_0 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 419.0
HFD1_k127_7158421_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000001218 234.0
HFD1_k127_7158421_2 - - - - 0.000000000000000005524 91.0
HFD1_k127_7158421_3 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.0000000000001632 70.0
HFD1_k127_7187272_0 Fibronectin type 3 domain - - - 0.00000000000000000000000000000002308 145.0
HFD1_k127_7187272_1 Aminotransferase class I and II K10907 - - 0.0000001026 58.0
HFD1_k127_7206299_0 Domain of unknown function (DUF1732) - - - 0.00000000000000000006785 94.0
HFD1_k127_7213242_0 NUDIX domain - - - 0.000000000000000000000000000000000006597 138.0
HFD1_k127_7213242_1 Outer membrane protein beta-barrel domain - - - 0.00000000000111 76.0
HFD1_k127_7213242_2 MlaD protein K02067 - - 0.000000001856 61.0
HFD1_k127_7217348_0 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 414.0
HFD1_k127_7217348_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000001282 160.0
HFD1_k127_7217348_2 PFAM DoxX K15977 - - 0.000000000000000000000000000000000006038 147.0
HFD1_k127_7232578_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000573 246.0
HFD1_k127_7232578_1 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000001163 69.0
HFD1_k127_7234901_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001019 291.0
HFD1_k127_7234901_1 Aminotransferase class-V - - - 0.00000000000000000000783 94.0
HFD1_k127_7246518_0 PFAM Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 297.0
HFD1_k127_7246518_1 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000001837 80.0
HFD1_k127_7246518_2 Adenine deaminase C-terminal domain K01486 - 3.5.4.2 0.0000000009836 61.0
HFD1_k127_7248692_0 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000001459 233.0
HFD1_k127_7248692_1 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000001308 183.0
HFD1_k127_7248692_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000001004 86.0
HFD1_k127_7250027_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - 0.0000000000000000000000000000000000000000000000001377 184.0
HFD1_k127_7250027_1 Transposase DDE domain - - - 0.000000000000000000000000001361 115.0
HFD1_k127_7250027_2 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000000000000003398 94.0
HFD1_k127_7250027_3 manually curated - - - 0.000000000000718 69.0
HFD1_k127_7250027_4 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - 0.0006697 45.0
HFD1_k127_7257643_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 293.0
HFD1_k127_7257643_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000001528 73.0
HFD1_k127_7259874_0 3-phosphoshikimate 1-carboxyvinyltransferase activity K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 364.0
HFD1_k127_7259874_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.0000000000000000000000000000000000009348 147.0
HFD1_k127_7259874_2 PFAM NHL repeat containing protein K13735 - - 0.00005754 55.0
HFD1_k127_7269939_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 393.0
HFD1_k127_7269939_1 - - - - 0.000000000000000004675 91.0
HFD1_k127_7269939_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000007208 85.0
HFD1_k127_7269939_3 Heat shock 70 kDa protein K04043 - - 0.000000000000000026 86.0
HFD1_k127_7274778_0 Rhodanese Homology Domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 491.0
HFD1_k127_7274778_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007906 274.0
HFD1_k127_7274778_2 Putative tRNA binding domain K06878 - - 0.00000000000000000000000000000000000000001195 158.0
HFD1_k127_7274778_3 - - - - 0.00000000009662 70.0
HFD1_k127_7275572_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 350.0
HFD1_k127_7280279_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 392.0
HFD1_k127_7280279_1 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000001039 225.0
HFD1_k127_7280279_2 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000009338 175.0
HFD1_k127_7282040_1 Glycosyl transferases group 1 - - - 0.0000002886 62.0
HFD1_k127_7283491_0 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 389.0
HFD1_k127_7283491_1 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.0000000000000000006125 101.0
HFD1_k127_7285897_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 446.0
HFD1_k127_7285897_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000401 214.0
HFD1_k127_7285897_2 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000001434 172.0
HFD1_k127_7291531_0 Glycine cleavage T-protein C-terminal barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 420.0
HFD1_k127_7291531_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000001409 94.0
HFD1_k127_7291531_2 Tetratricopeptide repeat - - - 0.00002319 56.0
HFD1_k127_7297903_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 436.0
HFD1_k127_7297903_1 Domain of unknown function (DUF4382) - - - 0.000000000000000004231 92.0
HFD1_k127_7300478_0 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 314.0
HFD1_k127_7302881_0 cellulase activity - - - 0.000000003303 69.0
HFD1_k127_7303129_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 574.0
HFD1_k127_7303129_1 PQQ-like domain K17713 - - 0.000000000000001474 91.0
HFD1_k127_7303129_2 - - - - 0.000000000006101 72.0
HFD1_k127_7307917_0 Protein involved in outer membrane biogenesis - - - 0.000000000000000003081 96.0
HFD1_k127_7314145_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 412.0
HFD1_k127_731869_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 356.0
HFD1_k127_7319140_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 436.0
HFD1_k127_7319140_1 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000004668 189.0
HFD1_k127_7319140_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000394 154.0
HFD1_k127_7319140_3 - - - - 0.000000000000003755 78.0
HFD1_k127_7319140_4 Patatin-like phospholipase - - - 0.000000006744 64.0
HFD1_k127_7329771_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000007045 185.0
HFD1_k127_7330367_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 372.0
HFD1_k127_7330367_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000002747 177.0
HFD1_k127_73341_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.00000000000000000000000000000000000000000000000000000000002502 213.0
HFD1_k127_73341_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000002264 159.0
HFD1_k127_7338307_0 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 6.499e-260 812.0
HFD1_k127_7338307_1 Carboxyl transferase domain - - - 9.927e-236 750.0
HFD1_k127_7338307_2 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 359.0
HFD1_k127_7338307_3 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000001478 227.0
HFD1_k127_7338307_4 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000000000009045 167.0
HFD1_k127_7339964_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 341.0
HFD1_k127_7339964_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 325.0
HFD1_k127_7339964_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000006652 181.0
HFD1_k127_7339964_3 ROK family K00845 - 2.7.1.2 0.000000000000421 70.0
HFD1_k127_7339964_4 - - - - 0.000000000004099 75.0
HFD1_k127_7342709_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 442.0
HFD1_k127_7342709_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000351 231.0
HFD1_k127_7342709_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000005028 208.0
HFD1_k127_7342709_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000002074 158.0
HFD1_k127_7342709_4 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000002682 123.0
HFD1_k127_7344074_0 PFAM Acetyltransferase (GNAT) family K06976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000721 252.0
HFD1_k127_7344074_1 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000104 94.0
HFD1_k127_7362389_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00006608 51.0
HFD1_k127_7366310_0 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003628 231.0
HFD1_k127_7376783_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000976 236.0
HFD1_k127_7376783_1 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000001387 181.0
HFD1_k127_7376783_2 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.000000000000000000000000000000007445 129.0
HFD1_k127_7376783_3 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000000004097 91.0
HFD1_k127_7388970_0 Domain of unknown function (DUF3471) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 361.0
HFD1_k127_7388970_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 345.0
HFD1_k127_7411333_0 PFAM aldo keto reductase K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 297.0
HFD1_k127_7411333_1 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000007069 117.0
HFD1_k127_7411333_2 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000005054 115.0
HFD1_k127_7414932_0 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000000000000000000000000002319 149.0
HFD1_k127_7414932_1 Transposase - - - 0.000000000000000001409 85.0
HFD1_k127_7414932_2 Involved in chromosome K16922 - - 0.00000000000002078 80.0
HFD1_k127_7414932_3 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000002958 74.0
HFD1_k127_7416965_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 586.0
HFD1_k127_7416965_1 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000001244 143.0
HFD1_k127_7418443_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 328.0
HFD1_k127_7418443_1 PFAM Rhomboid family - - - 0.0000000000000000000000000007286 123.0
HFD1_k127_7421632_0 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 401.0
HFD1_k127_7421632_1 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001159 238.0
HFD1_k127_7421632_2 - - - - 0.0000000000000000000000000000000000000001634 164.0
HFD1_k127_7424723_0 Cytochrome c K00406,K16255 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 354.0
HFD1_k127_7424723_1 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004727 256.0
HFD1_k127_7424723_2 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000000000000000000000000000000009716 242.0
HFD1_k127_7424723_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.0000000000000000000000000000002239 131.0
HFD1_k127_7425978_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000006679 141.0
HFD1_k127_7425978_1 - - - - 0.000000000000009766 79.0
HFD1_k127_7425978_2 - - - - 0.000005505 56.0
HFD1_k127_7427612_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 364.0
HFD1_k127_7427612_1 Major facilitator Superfamily K00943,K08217,K18833 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000129 194.0
HFD1_k127_7427612_2 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000003946 173.0
HFD1_k127_7427612_3 - - - - 0.0000000000005662 83.0
HFD1_k127_7427612_4 - - - - 0.0001224 52.0
HFD1_k127_7427612_5 DinB family - - - 0.000703 42.0
HFD1_k127_7436561_0 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 345.0
HFD1_k127_7436561_1 Transposase - - - 0.0000000000000000003774 89.0
HFD1_k127_7438635_0 P2 response regulator binding domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 402.0
HFD1_k127_7438635_1 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000003285 218.0
HFD1_k127_7443739_0 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 595.0
HFD1_k127_7443739_1 Peptidase S46 - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000006489 171.0
HFD1_k127_7443739_2 - - - - 0.0000000000000000000000000000000004646 134.0
HFD1_k127_7458707_0 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 542.0
HFD1_k127_7458707_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003242 280.0
HFD1_k127_7461273_0 serine-type peptidase activity K08676 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0 1118.0
HFD1_k127_7461273_1 DNA-binding transcriptional activator of the SARP family - - - 0.00001129 53.0
HFD1_k127_7464398_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000001098 232.0
HFD1_k127_7464398_1 - - - - 0.0000000000000000000000000000000000000000000001412 184.0
HFD1_k127_7464398_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000001415 143.0
HFD1_k127_7464398_3 Trm112p-like protein K09791 - - 0.000000000000002482 79.0
HFD1_k127_7464398_4 long-chain fatty acid transport protein - - - 0.0003892 52.0
HFD1_k127_7468160_0 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 374.0
HFD1_k127_7468160_1 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000008337 213.0
HFD1_k127_7468160_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000009118 201.0
HFD1_k127_7468160_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000001312 159.0
HFD1_k127_7468160_4 Ribonuclease B OB domain K03704 - - 0.0000000000000000000000000000001432 127.0
HFD1_k127_7468160_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000009373 122.0
HFD1_k127_7468160_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000001717 63.0
HFD1_k127_7468160_7 Ribosomal protein S21 K02970 - - 0.0000000003843 64.0
HFD1_k127_7474559_0 transport - - - 0.00000000000000000000000000000001628 136.0
HFD1_k127_7474559_1 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000001493 127.0
HFD1_k127_7474559_2 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000002881 124.0
HFD1_k127_7474559_3 WD40 domain protein beta Propeller K03641 - - 0.0000000000000617 78.0
HFD1_k127_7475309_0 hydroxymethylglutaryl-CoA reductase (NADPH) activity K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 334.0
HFD1_k127_7475309_1 ABC1 family K03688 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000002441 116.0
HFD1_k127_7476087_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 570.0
HFD1_k127_7476087_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000001048 230.0
HFD1_k127_7476087_2 4Fe-4S binding domain K11473 - - 0.00000000000000000000000000000000000000000000000000000009066 207.0
HFD1_k127_7476087_3 Glycolate oxidase subunit GlcE K11472 - - 0.00000000000000000000000000000000000000008083 166.0
HFD1_k127_7478408_0 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 552.0
HFD1_k127_7484148_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000007435 173.0
HFD1_k127_7484148_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000003585 177.0
HFD1_k127_7484148_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000003059 127.0
HFD1_k127_7485268_0 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000001053 199.0
HFD1_k127_7485268_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000002516 165.0
HFD1_k127_7486885_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001345 204.0
HFD1_k127_7495518_0 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000001994 233.0
HFD1_k127_7495518_1 Transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000004935 173.0
HFD1_k127_7498858_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000005771 211.0
HFD1_k127_7498858_1 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000008561 132.0
HFD1_k127_7501628_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000233 231.0
HFD1_k127_7501628_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000002059 179.0
HFD1_k127_7501628_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000004194 115.0
HFD1_k127_7501628_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000007463 72.0
HFD1_k127_7503413_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 285.0
HFD1_k127_7503413_1 Beta-lactamase - - - 0.0000000000000000000000000000000000002148 154.0
HFD1_k127_7506306_0 Glycosyl transferase 4-like K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 317.0
HFD1_k127_7506306_1 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.00000001067 64.0
HFD1_k127_7510706_0 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 439.0
HFD1_k127_7510706_1 Glycine zipper - - - 0.00000000000000000000000000000000000000000000000000000000000002806 221.0
HFD1_k127_7510706_2 Peptidase family M48 - - - 0.00000000000000000000001013 105.0
HFD1_k127_7510706_3 - - - - 0.0000000000000002916 85.0
HFD1_k127_7510706_4 - - - - 0.00000007658 55.0
HFD1_k127_7513203_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000001415 213.0
HFD1_k127_7513203_1 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000002267 152.0
HFD1_k127_7513203_2 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000001926 80.0
HFD1_k127_7517490_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 620.0
HFD1_k127_7525683_0 Zinc carboxypeptidase - - - 2.63e-298 938.0
HFD1_k127_7525683_1 MacB-like periplasmic core domain - - - 3.67e-290 927.0
HFD1_k127_7525683_2 Beta-lactamase K01286 - 3.4.16.4 0.0000000000002322 80.0
HFD1_k127_7527197_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 6.185e-227 731.0
HFD1_k127_7527197_1 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 495.0
HFD1_k127_7527197_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 429.0
HFD1_k127_7527197_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 295.0
HFD1_k127_7527197_4 Cupredoxin-like domain - - - 0.0000000000000000000000000000005247 128.0
HFD1_k127_7527197_5 - - - - 0.0000000000000000001476 92.0
HFD1_k127_7527197_6 Heavy metal transport detoxification protein - - - 0.000000003622 69.0
HFD1_k127_7534964_0 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000001764 221.0
HFD1_k127_7534964_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000002056 138.0
HFD1_k127_7534964_2 AntiSigma factor - - - 0.00000000000000000000000000006958 118.0
HFD1_k127_7553819_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 302.0
HFD1_k127_7554171_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.797e-203 664.0
HFD1_k127_7554171_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004377 271.0
HFD1_k127_7554171_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000002147 85.0
HFD1_k127_7557076_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 602.0
HFD1_k127_7557076_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 537.0
HFD1_k127_7557076_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 331.0
HFD1_k127_7557076_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003298 285.0
HFD1_k127_7557076_4 Participates in the control of copper homeostasis K06201 - - 0.000000000000000000000000000000000000000000000000000000000000000000006346 249.0
HFD1_k127_7557076_5 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000004405 223.0
HFD1_k127_7557076_6 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000004755 133.0
HFD1_k127_7557482_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 498.0
HFD1_k127_7557482_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000016 126.0
HFD1_k127_7557905_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 349.0
HFD1_k127_7563022_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000165 117.0
HFD1_k127_7591042_0 PFAM Glycoside hydrolase 15-related - - - 7.331e-201 649.0
HFD1_k127_7594856_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 432.0
HFD1_k127_7594856_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 350.0
HFD1_k127_7599628_0 COG0493 NADPH-dependent glutamate synthase beta chain and related K00266,K17722 - 1.3.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 394.0
HFD1_k127_7599628_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 382.0
HFD1_k127_7602850_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 457.0
HFD1_k127_7602850_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000234 272.0
HFD1_k127_7607535_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 417.0
HFD1_k127_7622012_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 595.0
HFD1_k127_7625223_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 300.0
HFD1_k127_7630731_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.000000000000000000000000000000000000000000000000002422 194.0
HFD1_k127_7630731_1 HTH domain - - - 0.0000000000000000000000000000000000000000204 162.0
HFD1_k127_7630731_2 Transcriptional regulator K02529 - - 0.0000000000000000000000004049 106.0
HFD1_k127_7631643_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002416 257.0
HFD1_k127_7631643_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.000000000000000000000000000000000000000001212 159.0
HFD1_k127_7631643_2 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000002944 153.0
HFD1_k127_7634357_0 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 532.0
HFD1_k127_7634357_1 peptidoglycan turnover - - - 0.00000005166 65.0
HFD1_k127_7641884_0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001431 273.0
HFD1_k127_7652840_0 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 293.0
HFD1_k127_7652840_1 PFAM Amino acid permease K03294 - - 0.0000000000001341 77.0
HFD1_k127_7652840_2 Putative phosphatase (DUF442) - - - 0.000000000001507 74.0
HFD1_k127_7652840_3 Domain of unknown function (DUF1772) - - - 0.00001029 52.0
HFD1_k127_7652840_4 cell adhesion involved in biofilm formation - - - 0.00002675 56.0
HFD1_k127_7663000_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 556.0
HFD1_k127_7669205_0 PFAM Integrase, catalytic core - - - 4.372e-198 623.0
HFD1_k127_7669205_1 PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein - - - 0.0003504 44.0
HFD1_k127_7688921_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001262 231.0
HFD1_k127_7694261_0 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000009826 253.0
HFD1_k127_76967_0 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004681 289.0
HFD1_k127_76967_1 - - - - 0.00000000000001757 83.0
HFD1_k127_7729663_0 MULE transposase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 577.0
HFD1_k127_7729663_1 Signal transduction protein with Nacht domain - - - 0.0000000006043 71.0
HFD1_k127_7729663_2 Sulfatase-modifying factor enzyme 1 - - - 0.00001503 57.0
HFD1_k127_7743470_0 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 442.0
HFD1_k127_7743470_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 0.00000000000000000000000000000000003186 138.0
HFD1_k127_7743470_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000001724 124.0
HFD1_k127_7743958_0 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 353.0
HFD1_k127_7743958_1 cell redox homeostasis - - - 0.000000000000000001807 100.0
HFD1_k127_7743958_2 Putative beta-lactamase-inhibitor-like, PepSY-like - - - 0.00000000000000003919 88.0
HFD1_k127_7743958_4 SnoaL-like domain - - - 0.000000007269 64.0
HFD1_k127_7759900_0 PFAM Protein kinase K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 412.0
HFD1_k127_7759900_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000007298 210.0
HFD1_k127_7775597_0 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 328.0
HFD1_k127_7775597_1 Ribonuclease HII K03470 - 3.1.26.4 0.00000000000000000000000002155 110.0
HFD1_k127_7782410_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 9.991e-320 997.0
HFD1_k127_7782410_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 346.0
HFD1_k127_7782410_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000003468 240.0
HFD1_k127_7782410_3 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000003965 232.0
HFD1_k127_7782410_4 Prokaryotic cytochrome b561 - - - 0.00000000000000000000002407 112.0
HFD1_k127_7782410_5 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000009671 106.0
HFD1_k127_78399_0 Aminotransferase class-III K03851,K15372 - 2.6.1.55,2.6.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000006177 254.0
HFD1_k127_7843265_0 electron transfer activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 448.0
HFD1_k127_7843265_1 - - - - 0.000000000000000000000000000000000006464 144.0
HFD1_k127_7857079_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000001085 148.0
HFD1_k127_7857079_1 - - - - 0.000000000000000000000003576 106.0
HFD1_k127_7857079_2 ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting K01551 GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005783,GO:0005789,GO:0006810,GO:0006811,GO:0006820,GO:0006950,GO:0006986,GO:0006996,GO:0007029,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007416,GO:0008104,GO:0008150,GO:0008509,GO:0009636,GO:0009987,GO:0010033,GO:0010256,GO:0010646,GO:0010647,GO:0010817,GO:0012505,GO:0015075,GO:0015103,GO:0015105,GO:0015318,GO:0015698,GO:0015700,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022857,GO:0023051,GO:0023052,GO:0023056,GO:0030424,GO:0030968,GO:0031974,GO:0031981,GO:0031984,GO:0032024,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0033036,GO:0033365,GO:0033554,GO:0034220,GO:0034613,GO:0034620,GO:0034976,GO:0035966,GO:0035967,GO:0036477,GO:0036498,GO:0042175,GO:0042221,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045048,GO:0045184,GO:0046685,GO:0046883,GO:0046887,GO:0048518,GO:0048522,GO:0048731,GO:0048856,GO:0050708,GO:0050714,GO:0050789,GO:0050794,GO:0050796,GO:0050808,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051179,GO:0051205,GO:0051222,GO:0051223,GO:0051234,GO:0051641,GO:0051716,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071310,GO:0071722,GO:0071816,GO:0071840,GO:0072657,GO:0090087,GO:0090150,GO:0090276,GO:0090277,GO:0097458,GO:0098656,GO:0098754,GO:0098827,GO:0120025,GO:1903530,GO:1903532,GO:1904951 3.6.3.16 0.0000105 52.0
HFD1_k127_7857079_3 - - - - 0.00002357 51.0
HFD1_k127_786650_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 354.0
HFD1_k127_786650_1 DinB superfamily - - - 0.000000000000000000000000000000005698 136.0
HFD1_k127_786650_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000001945 137.0
HFD1_k127_786650_3 esterase - - - 0.000000008217 56.0
HFD1_k127_7910065_0 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000001883 165.0
HFD1_k127_7915562_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 364.0
HFD1_k127_7915562_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000125 293.0
HFD1_k127_7925189_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 574.0
HFD1_k127_7925189_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 316.0
HFD1_k127_7925189_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001797 250.0
HFD1_k127_7925189_3 Acetyltransferase (GNAT) domain - - - 0.000000000004118 71.0
HFD1_k127_7961663_0 Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses K07497 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 342.0
HFD1_k127_7961663_1 PFAM Transposase IS3 IS911family K07483 - - 0.0000000000000000004391 89.0
HFD1_k127_7961663_2 Integrase core domain K07497 - - 0.0000000001067 67.0
HFD1_k127_7973458_0 - - - - 0.00000000000000000000000000000000000000001721 165.0
HFD1_k127_7975894_0 regulation of response to stimulus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 512.0
HFD1_k127_7975894_1 response to abiotic stimulus K03086,K06867 - - 0.000000000000000000000000000000000000003653 150.0
HFD1_k127_7993630_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 486.0
HFD1_k127_7993630_1 efflux transmembrane transporter activity K02004 - - 0.000000000000005147 77.0
HFD1_k127_7993630_2 efflux transmembrane transporter activity - - - 0.0001006 46.0
HFD1_k127_8008631_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 331.0
HFD1_k127_8031586_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003112 249.0
HFD1_k127_8031586_1 transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000001111 203.0
HFD1_k127_804419_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 373.0
HFD1_k127_804419_1 PFAM Cache K08738 - - 0.0000000000000000000000000000000000000000000000000000000000007198 238.0
HFD1_k127_804419_10 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000297 89.0
HFD1_k127_804419_11 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000004375 82.0
HFD1_k127_804419_12 general secretion pathway protein G K02456 - - 0.00005682 53.0
HFD1_k127_804419_13 RibD C-terminal domain - - - 0.0005064 46.0
HFD1_k127_804419_2 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000008072 204.0
HFD1_k127_804419_3 Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000002142 188.0
HFD1_k127_804419_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000002256 190.0
HFD1_k127_804419_5 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000001101 152.0
HFD1_k127_804419_6 YCII-related domain - - - 0.00000000000000000000000000000000000357 149.0
HFD1_k127_804419_7 PFAM Cache type 2 domain protein - - - 0.0000000000000000000000109 118.0
HFD1_k127_804419_8 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000009441 101.0
HFD1_k127_804419_9 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000004717 89.0
HFD1_k127_806089_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 360.0
HFD1_k127_806089_1 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000008652 273.0
HFD1_k127_806089_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000006566 207.0
HFD1_k127_806089_3 STAS domain K04749 - - 0.00000000000000000000000000000000000001113 155.0
HFD1_k127_806089_4 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000005233 141.0
HFD1_k127_806089_5 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757 - 2.7.11.1 0.00000000000000000000504 98.0
HFD1_k127_806144_0 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K01992,K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 481.0
HFD1_k127_806144_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 329.0
HFD1_k127_806144_2 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000005295 202.0
HFD1_k127_806144_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000006473 180.0
HFD1_k127_806695_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 565.0
HFD1_k127_806695_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000003776 213.0
HFD1_k127_806695_2 Fibronectin type 3 domain - - - 0.00000000007544 75.0
HFD1_k127_812825_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 497.0
HFD1_k127_812825_1 Elongator protein 3, MiaB family, Radical SAM K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 371.0
HFD1_k127_812825_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 308.0
HFD1_k127_812825_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000002694 110.0
HFD1_k127_814471_0 TonB-dependent Receptor Plug - - - 0.000003128 59.0
HFD1_k127_815638_0 ASPIC UnbV domain protein - - - 0.0 1321.0
HFD1_k127_815638_1 TonB dependent receptor - - - 1.87e-213 699.0
HFD1_k127_815638_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 311.0
HFD1_k127_815638_3 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002242 267.0
HFD1_k127_815638_4 PFAM TonB-dependent Receptor Plug K21573 - - 0.0000008623 56.0
HFD1_k127_817431_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000007541 261.0
HFD1_k127_817431_1 transporter K07238,K11021,K16267 - - 0.0000000000000000001923 100.0
HFD1_k127_822971_0 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000288 233.0
HFD1_k127_822971_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000002968 124.0
HFD1_k127_823146_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 608.0
HFD1_k127_823146_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000001653 215.0
HFD1_k127_823146_2 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000007826 152.0
HFD1_k127_823849_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 336.0
HFD1_k127_823849_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002841 292.0
HFD1_k127_823849_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000009949 144.0
HFD1_k127_824814_0 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 328.0
HFD1_k127_824814_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000006502 254.0
HFD1_k127_825586_0 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 349.0
HFD1_k127_827540_0 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000011 224.0
HFD1_k127_827540_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000677 189.0
HFD1_k127_827540_2 COG1910 Periplasmic molybdate-binding protein domain - - - 0.0003791 49.0
HFD1_k127_827905_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 7.517e-214 677.0
HFD1_k127_827905_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002095 268.0
HFD1_k127_827905_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000282 251.0
HFD1_k127_827905_3 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000001819 215.0
HFD1_k127_827905_4 3-hydroxyacyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000009859 205.0
HFD1_k127_827905_5 PFAM Inosine uridine-preferring nucleoside hydrolase K01250 - - 0.0000000000000000000000000000000000000000000000000001492 197.0
HFD1_k127_827905_6 Universal stress protein family - - - 0.00000000000000000000000000000000000000004144 173.0
HFD1_k127_83457_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000002144 177.0
HFD1_k127_83457_1 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000001318 116.0
HFD1_k127_836672_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 400.0
HFD1_k127_836672_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 396.0
HFD1_k127_836672_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000001226 162.0
HFD1_k127_838855_0 transmembrane transporter activity K18138 - - 0.0 1436.0
HFD1_k127_838855_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 408.0
HFD1_k127_839082_0 DEAD DEAH box helicase K03724 - - 1.434e-299 935.0
HFD1_k127_839082_1 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000001186 186.0
HFD1_k127_845595_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001663 226.0
HFD1_k127_845595_1 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000002196 67.0
HFD1_k127_845595_2 Domain of unknown function (DUF389) - - - 0.00001401 47.0
HFD1_k127_848640_0 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 1.706e-268 846.0
HFD1_k127_848640_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.00000000000000000000000000000000000000000000000000005331 194.0
HFD1_k127_850985_0 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000001853 216.0
HFD1_k127_850985_1 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000001465 160.0
HFD1_k127_857144_0 Ferrous iron transport protein B K04759 - - 4.427e-237 747.0
HFD1_k127_857144_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004641 274.0
HFD1_k127_857144_2 FeoA K04758 - - 0.0000000000000000001475 90.0
HFD1_k127_867275_0 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 461.0
HFD1_k127_867275_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003971 244.0
HFD1_k127_86819_0 Voltage gated chloride channel - - - 2.394e-194 619.0
HFD1_k127_86819_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000001929 249.0
HFD1_k127_86819_2 - - - - 0.00000000004749 64.0
HFD1_k127_86819_3 - - - - 0.00000001209 65.0
HFD1_k127_868212_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 519.0
HFD1_k127_868212_1 ABC-2 type transporter K01992 - - 0.000001607 55.0
HFD1_k127_869210_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 393.0
HFD1_k127_869210_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000007623 149.0
HFD1_k127_869210_2 RHS Repeat - - - 0.00002231 57.0
HFD1_k127_870533_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 518.0
HFD1_k127_870533_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 356.0
HFD1_k127_871198_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000005253 251.0
HFD1_k127_871198_1 Glutathione peroxidase - - - 0.00000000000000000000000000004071 133.0
HFD1_k127_871198_2 cell redox homeostasis - - - 0.00000000000000002039 87.0
HFD1_k127_871198_3 PASTA domain - - - 0.000000008468 60.0
HFD1_k127_871494_0 cyclic nucleotide binding K12132,K20074 - 2.7.11.1,3.1.3.16 0.00000000000000000000000000000000000000000000000000004275 214.0
HFD1_k127_871494_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000001897 123.0
HFD1_k127_871494_2 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.0000007588 51.0
HFD1_k127_873494_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006451 248.0
HFD1_k127_873494_1 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000002543 162.0
HFD1_k127_876443_0 AAA ATPase domain - - - 0.000000000000000000000000000000000003037 145.0
HFD1_k127_876443_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000005194 60.0
HFD1_k127_87687_0 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 305.0
HFD1_k127_87687_1 WG containing repeat - - - 0.00009197 52.0
HFD1_k127_87687_2 DinB family - - - 0.0001062 51.0
HFD1_k127_878224_0 L COG2826 Transposase and inactivated derivatives, IS30 family K07482 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 400.0
HFD1_k127_878224_2 Tetratricopeptide repeat - - - 0.00000000006764 64.0
HFD1_k127_8911_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 7.344e-206 651.0
HFD1_k127_8911_1 - - - - 0.000001459 61.0
HFD1_k127_892927_0 heme binding - - - 0.000000000000000000000000000000000000000000000007547 183.0
HFD1_k127_892927_1 PFAM regulatory protein, ArsR - - - 0.00000000001578 70.0
HFD1_k127_892927_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.00000003855 57.0
HFD1_k127_901519_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.000000000000000000006171 98.0
HFD1_k127_901885_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 327.0
HFD1_k127_901885_1 Belongs to the universal stress protein A family - - - 0.000000000003814 77.0
HFD1_k127_903271_0 ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009826 271.0
HFD1_k127_903271_1 Glycosyltransferase family 87 - - - 0.000000000000000000002978 107.0
HFD1_k127_903271_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000001218 87.0
HFD1_k127_903491_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 455.0
HFD1_k127_903491_1 Subtilase family - - - 0.000000000000002187 78.0
HFD1_k127_908986_0 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000004025 154.0
HFD1_k127_912255_0 Protein of unknown function (DUF445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 356.0
HFD1_k127_912255_1 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000483 240.0
HFD1_k127_916679_0 Chain length determinant protein K16554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 299.0
HFD1_k127_916679_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000007062 262.0
HFD1_k127_920554_0 PFAM Transposase, IS4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 490.0
HFD1_k127_922046_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000005671 210.0
HFD1_k127_922046_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000008981 164.0
HFD1_k127_930813_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000007923 239.0
HFD1_k127_936619_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001379 281.0
HFD1_k127_936619_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000002253 139.0
HFD1_k127_936619_2 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.00000000000000000000000000000002358 132.0
HFD1_k127_936619_3 Transposase IS200 like - - - 0.00000000000001949 83.0
HFD1_k127_936947_0 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 538.0
HFD1_k127_936947_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 437.0
HFD1_k127_936947_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 353.0
HFD1_k127_937150_0 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 410.0
HFD1_k127_937150_1 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 359.0
HFD1_k127_937150_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003992 249.0
HFD1_k127_937150_3 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000016 240.0
HFD1_k127_939107_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 289.0
HFD1_k127_940783_0 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 548.0
HFD1_k127_940783_1 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 368.0
HFD1_k127_940783_2 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000279 162.0
HFD1_k127_940783_3 PIN domain - - - 0.0000000000000326 74.0
HFD1_k127_940783_4 - - - - 0.0001268 44.0
HFD1_k127_94150_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 354.0
HFD1_k127_94150_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000003442 134.0
HFD1_k127_94150_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000003669 55.0
HFD1_k127_945543_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 424.0
HFD1_k127_945543_1 Lipopolysaccharide-assembly - - - 0.000000000000000000000003372 108.0
HFD1_k127_945543_2 - - - - 0.00000002517 66.0
HFD1_k127_946_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 308.0
HFD1_k127_946_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000008883 260.0
HFD1_k127_946_2 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000000000000000000972 178.0
HFD1_k127_949428_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 9.841e-267 842.0
HFD1_k127_949428_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003341 287.0
HFD1_k127_949428_2 Helix-hairpin-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009746 272.0
HFD1_k127_949428_3 Belongs to the universal stress protein A family - - - 0.000000000002276 76.0
HFD1_k127_950811_0 COG3121 P pilus assembly protein, chaperone PapD - - - 0.00003358 55.0
HFD1_k127_951591_0 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001227 274.0
HFD1_k127_951591_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000002107 153.0
HFD1_k127_951591_2 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000002659 136.0
HFD1_k127_963332_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 370.0
HFD1_k127_963332_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 309.0
HFD1_k127_963332_2 penicillin binding K05367 - 2.4.1.129 0.0000000000000000000000000000012 136.0
HFD1_k127_967630_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000239 120.0
HFD1_k127_97750_0 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000005799 251.0
HFD1_k127_97750_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000003099 110.0
HFD1_k127_97750_2 Belongs to the peptidase S1B family K01183,K03791 - 3.2.1.14 0.0000000000000003991 93.0
HFD1_k127_9786_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 335.0
HFD1_k127_9786_1 Rhomboid family - - - 0.00000000000000000000000000000000000009988 153.0
HFD1_k127_9786_2 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.00000000000000000000000001513 111.0
HFD1_k127_988430_0 ATPases associated with a variety of cellular activities K06147 - - 0.00000000000000000000000000000000000000000000003906 170.0
HFD1_k127_988430_1 - - - - 0.0000000000000000000000000000000000000000000002308 172.0
HFD1_k127_99024_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 477.0
HFD1_k127_99024_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000004904 66.0
HFD1_k127_99166_0 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 363.0
HFD1_k127_99166_1 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000001127 179.0
HFD1_k127_99166_2 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000001391 155.0
HFD1_k127_992503_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 557.0
HFD1_k127_992503_1 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000133 113.0
HFD1_k127_992569_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 6.8e-215 692.0
HFD1_k127_992569_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 395.0
HFD1_k127_992569_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 367.0
HFD1_k127_992569_3 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000001524 221.0
HFD1_k127_992569_4 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000005355 183.0
HFD1_k127_992569_5 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000009008 151.0
HFD1_k127_992569_6 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000001691 160.0
HFD1_k127_992569_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000001246 126.0
HFD1_k127_996408_0 oligopeptide transporter, OPT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 546.0
HFD1_k127_996982_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1187.0