Overview

ID MAG01614
Name HFD1_bin.21
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class BSN033
Order BSN033
Family UBA1163
Genus UBA1163
Species
Assembly information
Completeness (%) 79.44
Contamination (%) 2.06
GC content (%) 48.0
N50 (bp) 7,011
Genome size (bp) 3,402,798

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3175

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1000083_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 7.399e-240 765.0
HFD1_k127_1000083_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 597.0
HFD1_k127_1000083_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000002702 137.0
HFD1_k127_1000083_3 PFAM regulatory protein, MerR - - - 0.000000000000000000000003289 106.0
HFD1_k127_1000083_4 Belongs to the UPF0145 family - - - 0.000000000001507 74.0
HFD1_k127_1000083_5 Belongs to the 'phage' integrase family - - - 0.00002975 49.0
HFD1_k127_1005398_0 S1, RNA binding domain K06959 - - 0.0 1116.0
HFD1_k127_1005398_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000003097 137.0
HFD1_k127_1005398_2 self proteolysis - - - 0.000000000000000000000000000000000579 139.0
HFD1_k127_1008849_0 Domain of unknown function (DUF4301) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 565.0
HFD1_k127_1008849_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 359.0
HFD1_k127_1008849_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000001764 224.0
HFD1_k127_1008849_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000006622 222.0
HFD1_k127_1062915_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 1.245e-216 701.0
HFD1_k127_1062915_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 537.0
HFD1_k127_1062915_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 416.0
HFD1_k127_1062915_3 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K15022 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 337.0
HFD1_k127_1062915_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000005588 155.0
HFD1_k127_1062915_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000004865 125.0
HFD1_k127_1062915_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000001003 119.0
HFD1_k127_1068789_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 562.0
HFD1_k127_1068789_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 387.0
HFD1_k127_1068789_2 Aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000024 260.0
HFD1_k127_1068789_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000001883 233.0
HFD1_k127_1085095_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000004681 221.0
HFD1_k127_1085095_1 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000000007982 190.0
HFD1_k127_1085095_2 outer membrane autotransporter barrel domain - - - 0.000000000000000000000000001946 121.0
HFD1_k127_1085095_3 KaiB domain K08481 - - 0.0000000000000001299 83.0
HFD1_k127_1085095_4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000003833 54.0
HFD1_k127_1085640_0 Belongs to the UPF0251 family - - - 0.000000000000000000000000000000000000000006581 158.0
HFD1_k127_1085640_1 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000001441 151.0
HFD1_k127_1085640_2 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.0000000000000008227 85.0
HFD1_k127_1085640_3 Putative regulatory protein - - - 0.0000000006782 63.0
HFD1_k127_1085640_4 MoaE protein K03635 - 2.8.1.12 0.0000004986 51.0
HFD1_k127_1085640_5 Belongs to the HesB IscA family - - - 0.00005664 47.0
HFD1_k127_1104374_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 303.0
HFD1_k127_1104374_1 (ABC) transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001827 246.0
HFD1_k127_1104374_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000489 155.0
HFD1_k127_1104374_3 PFAM ABC transporter K01996 - - 0.0000000000000000000000000009858 114.0
HFD1_k127_1122905_0 dEAD DEAH box helicase K06877 - - 1.004e-295 927.0
HFD1_k127_1122905_1 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 365.0
HFD1_k127_1122905_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006727 261.0
HFD1_k127_1122905_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000001287 91.0
HFD1_k127_1122905_4 Putative transmembrane protein (PGPGW) - - - 0.0000000001425 65.0
HFD1_k127_1124296_0 ferredoxin-NADP+ reductase activity K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 361.0
HFD1_k127_1124296_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 358.0
HFD1_k127_1124296_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000001831 242.0
HFD1_k127_1124296_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000002546 217.0
HFD1_k127_1124296_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000006385 196.0
HFD1_k127_1124296_5 DNA polymerase beta domain protein region - - - 0.00000000000000000000000000001721 121.0
HFD1_k127_1124296_6 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000001637 115.0
HFD1_k127_1124296_7 HEPN domain - - - 0.000000000000000006816 88.0
HFD1_k127_114139_0 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 358.0
HFD1_k127_114139_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005522 268.0
HFD1_k127_114139_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000004693 184.0
HFD1_k127_114139_3 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000005507 153.0
HFD1_k127_114139_4 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000116 53.0
HFD1_k127_1161319_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 479.0
HFD1_k127_1161319_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 380.0
HFD1_k127_1161319_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 349.0
HFD1_k127_1161319_3 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 317.0
HFD1_k127_1161319_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K02302,K02303,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000007448 248.0
HFD1_k127_1161319_5 Rod shape-determining protein K03569 - - 0.0000000000000000000000000000000000000000000218 162.0
HFD1_k127_1173809_0 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 539.0
HFD1_k127_1173809_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 426.0
HFD1_k127_1173809_2 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 390.0
HFD1_k127_1173809_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 288.0
HFD1_k127_1173809_4 PFAM response regulator receiver K07657,K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 288.0
HFD1_k127_1173809_5 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005637 246.0
HFD1_k127_1181181_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 2.984e-260 815.0
HFD1_k127_1181181_1 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 548.0
HFD1_k127_1181181_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 319.0
HFD1_k127_1181181_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 302.0
HFD1_k127_1181181_4 pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003483 289.0
HFD1_k127_1181181_5 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000007849 204.0
HFD1_k127_1181181_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000005645 97.0
HFD1_k127_1181181_7 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000005608 80.0
HFD1_k127_118161_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 334.0
HFD1_k127_118161_1 helix_turn_helix, Lux Regulon - - - 0.00001184 51.0
HFD1_k127_1184386_0 DEAD/H associated K03724 - - 0.0 1240.0
HFD1_k127_1184386_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000004162 218.0
HFD1_k127_1184386_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000002278 172.0
HFD1_k127_1194254_0 Cys/Met metabolism PLP-dependent enzyme K01758,K01761 - 4.4.1.1,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 530.0
HFD1_k127_1194254_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 434.0
HFD1_k127_1194254_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000001578 174.0
HFD1_k127_1194254_3 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00005441 46.0
HFD1_k127_1214400_0 von Willebrand factor, type A K07114 - - 2.686e-295 925.0
HFD1_k127_1214400_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 517.0
HFD1_k127_1214400_10 - - - - 0.00000000000000000008584 91.0
HFD1_k127_1214400_11 PHP domain protein - - - 0.000046 54.0
HFD1_k127_1214400_12 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0004845 45.0
HFD1_k127_1214400_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 440.0
HFD1_k127_1214400_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000003207 273.0
HFD1_k127_1214400_4 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000001001 274.0
HFD1_k127_1214400_5 chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000000000002942 217.0
HFD1_k127_1214400_6 - - - - 0.0000000000000000000000000006976 121.0
HFD1_k127_1214400_8 PFAM CheW domain protein K03408 - - 0.000000000000000000000006352 106.0
HFD1_k127_1214400_9 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000001591 107.0
HFD1_k127_1223063_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 2.119e-246 788.0
HFD1_k127_1223063_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 502.0
HFD1_k127_1223063_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 311.0
HFD1_k127_1223063_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000002336 230.0
HFD1_k127_1223063_4 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000002158 169.0
HFD1_k127_1223063_5 PFAM glycine cleavage H-protein - - - 0.000000000000000000000007231 111.0
HFD1_k127_1223063_6 Glycine cleavage H-protein - - - 0.00000000000000000000002295 109.0
HFD1_k127_1223063_7 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000331 54.0
HFD1_k127_1226176_0 PFAM V-type ATPase 116 kDa K02123 - - 3.788e-243 769.0
HFD1_k127_1226176_1 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000002566 248.0
HFD1_k127_1226176_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000004189 217.0
HFD1_k127_1226176_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000001168 192.0
HFD1_k127_1226176_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000002691 175.0
HFD1_k127_1226176_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000000003844 169.0
HFD1_k127_1226176_6 subunit (C K02119 - - 0.0000000000000000000000000001251 117.0
HFD1_k127_1248401_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 504.0
HFD1_k127_1248401_1 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000004561 203.0
HFD1_k127_1248401_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000545 199.0
HFD1_k127_1248401_3 O-Antigen ligase K16705 - - 0.0000000000000000000000000000000000000000003133 178.0
HFD1_k127_1248401_4 VanZ like family - - - 0.000000000000000000000000000000000000000001094 160.0
HFD1_k127_1248401_5 Transcription termination factor nusG - - - 0.00000000000000000000005338 105.0
HFD1_k127_1248401_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000001595 79.0
HFD1_k127_1248401_7 23S rRNA-intervening sequence protein - - - 0.00000001875 61.0
HFD1_k127_1249867_0 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 355.0
HFD1_k127_1249867_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000746 184.0
HFD1_k127_1249867_2 Rhodanese Homology Domain - - - 0.0000000000000000000005645 97.0
HFD1_k127_1251679_0 Catalase K03781 - 1.11.1.6 2.58e-299 920.0
HFD1_k127_1251679_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 339.0
HFD1_k127_1251679_10 Universal stress protein - - - 0.0000000000000000004556 93.0
HFD1_k127_1251679_11 Helix-turn-helix domain - - - 0.00001148 48.0
HFD1_k127_1251679_2 Rubredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 295.0
HFD1_k127_1251679_3 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001201 256.0
HFD1_k127_1251679_4 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000002711 248.0
HFD1_k127_1251679_5 Belongs to the Fur family K09825 - - 0.00000000000000000000000000000000000335 141.0
HFD1_k127_1251679_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000002025 136.0
HFD1_k127_1251679_7 - - - - 0.000000000000000000000008757 102.0
HFD1_k127_1251679_8 Universal stress protein - - - 0.00000000000000000000009216 104.0
HFD1_k127_1268294_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 459.0
HFD1_k127_1268294_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 368.0
HFD1_k127_1268294_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000001146 196.0
HFD1_k127_1268294_3 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000004768 133.0
HFD1_k127_1268294_4 4 iron, 4 sulfur cluster binding K00176,K05524 - 1.2.7.3 0.000000000000000001126 87.0
HFD1_k127_1270644_0 GTP-binding protein TypA K06207 - - 1.206e-256 803.0
HFD1_k127_1270644_1 Belongs to the DEAD box helicase family K05592 GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001827 291.0
HFD1_k127_1270644_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000003054 84.0
HFD1_k127_1271918_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.067e-238 751.0
HFD1_k127_1271918_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 477.0
HFD1_k127_1271918_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 370.0
HFD1_k127_1271918_3 PFAM Pyruvate K00177 - 1.2.7.3 0.0000000000000000000000000000000000000002211 155.0
HFD1_k127_1271918_4 4 iron, 4 sulfur cluster binding K00176,K05524 - 1.2.7.3 0.000000000000000004005 86.0
HFD1_k127_128263_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 379.0
HFD1_k127_128263_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 301.0
HFD1_k127_128263_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000001301 127.0
HFD1_k127_1284196_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1152.0
HFD1_k127_1284196_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000006911 111.0
HFD1_k127_1302906_0 permease - - - 0.000000000000000000000000000000000000000000000000000000009652 212.0
HFD1_k127_1302906_1 Protein of unknown function (DUF4242) - - - 0.0000000000000000000004531 98.0
HFD1_k127_1302906_2 Alkylmercury lyase - - - 0.0000000000000000000141 94.0
HFD1_k127_1302906_4 Alkylmercury lyase - - - 0.0000000000001418 72.0
HFD1_k127_1302906_5 - - - - 0.0000000004743 70.0
HFD1_k127_1302906_6 regulation of DNA-templated transcription, elongation - - - 0.00002729 53.0
HFD1_k127_131975_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 499.0
HFD1_k127_131975_1 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 356.0
HFD1_k127_131975_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 334.0
HFD1_k127_131975_3 Pyridoxal-phosphate dependent enzyme K01883,K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 298.0
HFD1_k127_1319771_0 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 556.0
HFD1_k127_1319771_1 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000002474 261.0
HFD1_k127_1319771_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002322 237.0
HFD1_k127_1319771_3 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000001226 181.0
HFD1_k127_1332681_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 1.273e-234 736.0
HFD1_k127_1332681_1 TIGRFAM hopanoid-associated sugar epimerase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000009353 251.0
HFD1_k127_1332681_2 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000007554 190.0
HFD1_k127_1332681_3 alpha beta - - - 0.00000000000000000000000000000000000000000000001306 186.0
HFD1_k127_1332681_4 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000001569 120.0
HFD1_k127_1332681_5 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000001656 90.0
HFD1_k127_1332681_7 FtsZ-dependent cytokinesis - - - 0.00000000000002867 76.0
HFD1_k127_1342862_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 559.0
HFD1_k127_1342862_1 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003928 252.0
HFD1_k127_1342862_2 Cysteine-rich secretory protein family - - - 0.00000000000000000009757 96.0
HFD1_k127_1342862_3 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.00000003639 65.0
HFD1_k127_1342862_4 SPFH domain-Band 7 family - - - 0.00009614 54.0
HFD1_k127_1365669_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 377.0
HFD1_k127_1365669_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 360.0
HFD1_k127_1365669_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 324.0
HFD1_k127_1365669_3 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 302.0
HFD1_k127_1365669_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001425 276.0
HFD1_k127_1365669_5 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000001034 231.0
HFD1_k127_1365669_6 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000006729 230.0
HFD1_k127_1365669_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000331 220.0
HFD1_k127_1365669_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000005851 159.0
HFD1_k127_1365669_9 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000009164 147.0
HFD1_k127_1418192_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 591.0
HFD1_k127_1418192_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 351.0
HFD1_k127_1418192_2 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 294.0
HFD1_k127_1418192_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000009152 199.0
HFD1_k127_1418192_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000005047 190.0
HFD1_k127_1418192_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 0.0000000000000000000000000000005715 126.0
HFD1_k127_1418192_6 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000005791 111.0
HFD1_k127_1418192_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000003509 81.0
HFD1_k127_1419380_0 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01615 - 4.1.1.70 4.53e-301 930.0
HFD1_k127_1419380_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000006722 172.0
HFD1_k127_1428666_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002875 270.0
HFD1_k127_1428666_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002237 255.0
HFD1_k127_1428666_2 4Fe-4S single cluster domain - - - 0.0000000000000002021 80.0
HFD1_k127_1428666_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695,K11050 - - 0.0000000002512 63.0
HFD1_k127_1433975_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.612e-201 633.0
HFD1_k127_1433975_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 324.0
HFD1_k127_1433975_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 310.0
HFD1_k127_1447317_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 437.0
HFD1_k127_1447317_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 428.0
HFD1_k127_1447317_10 cheY-homologous receiver domain K07658 - - 0.000000000000000000000009214 105.0
HFD1_k127_1447317_11 Tetratricopeptide repeat - - - 0.0000000002239 72.0
HFD1_k127_1447317_2 fumarylacetoacetate (FAA) hydrolase K14259 - 4.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000178 287.0
HFD1_k127_1447317_3 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008338 273.0
HFD1_k127_1447317_4 EcsC protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001865 244.0
HFD1_k127_1447317_5 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000001135 186.0
HFD1_k127_1447317_6 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000000002032 157.0
HFD1_k127_1447317_7 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000001647 134.0
HFD1_k127_1447317_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000009767 136.0
HFD1_k127_1468034_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.785e-223 698.0
HFD1_k127_1468034_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.897e-214 681.0
HFD1_k127_1468034_2 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 498.0
HFD1_k127_1468034_3 alcohol dehydrogenase K19954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 403.0
HFD1_k127_1468034_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003138 277.0
HFD1_k127_1468034_5 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001773 257.0
HFD1_k127_1468034_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000002764 177.0
HFD1_k127_1468034_7 Glycine cleavage H-protein - - - 0.00000000000000000000002295 100.0
HFD1_k127_1468034_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K18337 - 1.1.1.173,1.1.1.377,1.1.1.378 0.0000001509 57.0
HFD1_k127_1477419_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.456e-222 712.0
HFD1_k127_1477419_1 NMT1-like family K02051,K15553 - - 0.00000000000000000000000000000000000002178 156.0
HFD1_k127_1488192_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 548.0
HFD1_k127_1488192_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 307.0
HFD1_k127_1488192_2 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000441 287.0
HFD1_k127_1488192_3 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000001839 239.0
HFD1_k127_1488192_4 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000001629 174.0
HFD1_k127_1488192_5 Alkylmercury lyase - - - 0.00000000000000000002906 93.0
HFD1_k127_1488192_7 Alkylmercury lyase - - - 0.0000000002142 63.0
HFD1_k127_1494558_0 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 512.0
HFD1_k127_1494558_1 CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 457.0
HFD1_k127_1494558_2 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001646 259.0
HFD1_k127_1494558_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000002094 91.0
HFD1_k127_1494558_4 translation elongation factor activity K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 0.000000000000007503 74.0
HFD1_k127_1494558_5 - - - - 0.0000001547 53.0
HFD1_k127_1494558_7 Putative esterase - - - 0.00003865 56.0
HFD1_k127_1500796_0 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 609.0
HFD1_k127_1500796_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 406.0
HFD1_k127_1500796_2 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 342.0
HFD1_k127_1500796_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000005406 220.0
HFD1_k127_1500796_4 B12 binding domain - - - 0.000000000000000000000000003706 118.0
HFD1_k127_1506171_0 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 350.0
HFD1_k127_1506171_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000003562 207.0
HFD1_k127_1506171_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000006782 180.0
HFD1_k127_1506171_3 ACT domain - - - 0.0000000000000000000000000000000000000000000006791 169.0
HFD1_k127_1507995_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000003141 254.0
HFD1_k127_1507995_1 radical SAM domain protein K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005256 265.0
HFD1_k127_1524055_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 535.0
HFD1_k127_1524055_1 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 430.0
HFD1_k127_1524055_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000002277 207.0
HFD1_k127_1524055_11 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000001868 198.0
HFD1_k127_1524055_12 Putative regulatory protein - - - 0.000000000000000000000000000001557 124.0
HFD1_k127_1524055_13 cAMP biosynthetic process - - - 0.00000000000000000001094 103.0
HFD1_k127_1524055_14 - - - - 0.0000000003178 65.0
HFD1_k127_1524055_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 410.0
HFD1_k127_1524055_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 389.0
HFD1_k127_1524055_4 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 363.0
HFD1_k127_1524055_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 336.0
HFD1_k127_1524055_6 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 287.0
HFD1_k127_1524055_7 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001943 248.0
HFD1_k127_1524055_8 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000004367 243.0
HFD1_k127_1524055_9 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000002178 224.0
HFD1_k127_1534986_0 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000003335 143.0
HFD1_k127_1534986_1 response regulator K07814 - - 0.00000000000000000000000000001582 123.0
HFD1_k127_1534986_2 PAS fold - - - 0.0000000000000000001648 101.0
HFD1_k127_1534986_3 PFAM Transposase - - - 0.00001996 51.0
HFD1_k127_1590804_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 4.008e-288 907.0
HFD1_k127_1590804_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 469.0
HFD1_k127_1590804_2 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 405.0
HFD1_k127_1590804_3 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000008793 157.0
HFD1_k127_1590804_4 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000004414 105.0
HFD1_k127_1590804_5 - - - - 0.000000000000000001547 87.0
HFD1_k127_1590804_6 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000000005371 88.0
HFD1_k127_1590804_7 - - - - 0.00000000000000004836 85.0
HFD1_k127_1608739_0 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 469.0
HFD1_k127_1608739_1 PFAM ATP dependent DNA ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 433.0
HFD1_k127_1608739_2 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 425.0
HFD1_k127_1608739_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 293.0
HFD1_k127_1608739_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000105 225.0
HFD1_k127_1608739_5 - - - - 0.000000000000000000000000000000000000000000000000000002739 198.0
HFD1_k127_1618121_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 2.329e-254 799.0
HFD1_k127_1618121_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.474e-231 732.0
HFD1_k127_1618121_10 OmpA family - - - 0.00000000000000000003604 99.0
HFD1_k127_1618121_11 DUF167 K09131 - - 0.0000000000000000002123 91.0
HFD1_k127_1618121_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000001136 88.0
HFD1_k127_1618121_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 578.0
HFD1_k127_1618121_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 423.0
HFD1_k127_1618121_4 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001281 218.0
HFD1_k127_1618121_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000001225 178.0
HFD1_k127_1618121_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000007788 180.0
HFD1_k127_1618121_7 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000009692 168.0
HFD1_k127_1618121_8 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000001389 162.0
HFD1_k127_1618121_9 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000005436 144.0
HFD1_k127_1623060_0 Belongs to the ClpX chaperone family - - - 1.426e-210 670.0
HFD1_k127_1623060_1 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 341.0
HFD1_k127_1623060_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000001161 171.0
HFD1_k127_1623060_3 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.00006219 47.0
HFD1_k127_162743_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 2.742e-256 803.0
HFD1_k127_162743_1 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000008894 214.0
HFD1_k127_162743_2 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000002477 182.0
HFD1_k127_162743_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000004643 174.0
HFD1_k127_162743_4 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000002425 119.0
HFD1_k127_1627492_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.438e-198 625.0
HFD1_k127_1627492_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.295e-194 614.0
HFD1_k127_1627492_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 428.0
HFD1_k127_1627492_3 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 372.0
HFD1_k127_1627492_4 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 331.0
HFD1_k127_1627492_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007645 274.0
HFD1_k127_1627492_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000002933 223.0
HFD1_k127_1627492_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000003482 146.0
HFD1_k127_1627492_8 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K00605,K18847 - 2.1.2.1,2.1.2.10,2.2.1.8 0.0000006677 52.0
HFD1_k127_1630623_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 596.0
HFD1_k127_1630623_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
HFD1_k127_1630623_3 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000000000000000000000000000000008681 171.0
HFD1_k127_1630623_4 PRC-barrel domain - - - 0.00000002877 61.0
HFD1_k127_1639177_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 487.0
HFD1_k127_1639177_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 432.0
HFD1_k127_1639177_2 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 334.0
HFD1_k127_164101_0 Iron-sulfur cluster-binding domain K06871 - - 9.165e-220 688.0
HFD1_k127_164101_1 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002031 243.0
HFD1_k127_164101_2 - - - - 0.00000000000000000000000000000000000002922 154.0
HFD1_k127_164101_3 Sulfatase K01130 - 3.1.6.1 0.000004425 49.0
HFD1_k127_1642370_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 422.0
HFD1_k127_1642370_1 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 372.0
HFD1_k127_1642370_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000007533 184.0
HFD1_k127_1642370_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000008281 125.0
HFD1_k127_1648712_0 Belongs to the glycosyl hydrolase 57 family - - - 1.269e-198 648.0
HFD1_k127_1648712_1 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 612.0
HFD1_k127_1648712_2 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 458.0
HFD1_k127_1648712_3 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 362.0
HFD1_k127_1648712_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 299.0
HFD1_k127_1648712_5 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004977 245.0
HFD1_k127_1648712_6 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K04488 - - 0.0000000000000000000000000000000000000000000008852 168.0
HFD1_k127_1660393_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 621.0
HFD1_k127_1660393_1 ethanolamine kinase activity K07251 - 2.7.1.89 0.0000000000000000000004761 106.0
HFD1_k127_1663834_0 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 586.0
HFD1_k127_1663834_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 379.0
HFD1_k127_1663834_2 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000001879 126.0
HFD1_k127_1664390_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 566.0
HFD1_k127_1664390_1 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 535.0
HFD1_k127_1664390_2 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 349.0
HFD1_k127_1664390_3 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 350.0
HFD1_k127_1664390_4 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 295.0
HFD1_k127_1664390_5 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000002017 263.0
HFD1_k127_1664390_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000003505 211.0
HFD1_k127_1664390_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000002711 134.0
HFD1_k127_1664390_8 4Fe-4S binding domain - - - 0.00000000000000002282 87.0
HFD1_k127_1664390_9 HAD-hyrolase-like - - - 0.00004733 48.0
HFD1_k127_1670564_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 5e-324 1007.0
HFD1_k127_1670564_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 570.0
HFD1_k127_1670564_10 Oxidoreductase molybdopterin binding domain K00387,K07147 - 1.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000009177 269.0
HFD1_k127_1670564_11 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003676 252.0
HFD1_k127_1670564_12 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003135 247.0
HFD1_k127_1670564_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000135 239.0
HFD1_k127_1670564_14 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000005459 229.0
HFD1_k127_1670564_15 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000002976 220.0
HFD1_k127_1670564_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 447.0
HFD1_k127_1670564_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 439.0
HFD1_k127_1670564_4 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 424.0
HFD1_k127_1670564_5 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 330.0
HFD1_k127_1670564_6 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 321.0
HFD1_k127_1670564_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 314.0
HFD1_k127_1670564_8 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 321.0
HFD1_k127_1670564_9 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 301.0
HFD1_k127_167419_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.166e-291 902.0
HFD1_k127_167419_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 9.694e-239 757.0
HFD1_k127_167419_2 GUN4-like - - - 0.000000000000000008304 86.0
HFD1_k127_167419_3 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000001489 64.0
HFD1_k127_1678274_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 2.273e-236 739.0
HFD1_k127_1678274_1 Major facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 600.0
HFD1_k127_1678274_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 598.0
HFD1_k127_1678274_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 572.0
HFD1_k127_1678274_4 Stage II sporulation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 552.0
HFD1_k127_1678274_5 Domain of unknown function (DUF4922) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 362.0
HFD1_k127_1678274_6 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000009072 227.0
HFD1_k127_1678274_7 PFAM Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000008586 213.0
HFD1_k127_1678274_8 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000001934 169.0
HFD1_k127_1678274_9 - - - - 0.00000303 57.0
HFD1_k127_1684585_0 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 375.0
HFD1_k127_1684585_1 Cold shock protein K03704 - - 0.00000000000000000000001392 102.0
HFD1_k127_1684585_2 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.0003547 46.0
HFD1_k127_1684585_3 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0006898 53.0
HFD1_k127_1715814_0 Glycosyl hydrolases family 15 - - - 1.751e-215 685.0
HFD1_k127_1715814_1 Belongs to the TPP enzyme family K00156 - 1.2.5.1 0.00000000000000000000000007925 108.0
HFD1_k127_1715814_2 E1-E2 ATPase K17686 - 3.6.3.54 0.00000000003725 65.0
HFD1_k127_1741515_0 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 1.615e-225 708.0
HFD1_k127_1741515_1 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 1.148e-210 664.0
HFD1_k127_1741515_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 516.0
HFD1_k127_1741515_3 extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 371.0
HFD1_k127_1741515_4 helix_turn_helix gluconate operon transcriptional repressor K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005304 282.0
HFD1_k127_1741515_5 translation release factor activity - - - 0.000000000000000000000005414 102.0
HFD1_k127_1741515_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000007628 109.0
HFD1_k127_1777093_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 465.0
HFD1_k127_1777093_1 copper resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 443.0
HFD1_k127_1777093_2 PFAM Endonuclease exonuclease phosphatase K06896 - 3.1.3.90 0.000000000000000000000000000000000000000000000000000000000000005321 229.0
HFD1_k127_1777093_3 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.00000000000000000000000000000000000004932 150.0
HFD1_k127_1778795_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 564.0
HFD1_k127_1778795_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 541.0
HFD1_k127_1778795_10 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003182 274.0
HFD1_k127_1778795_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004137 281.0
HFD1_k127_1778795_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001531 253.0
HFD1_k127_1778795_13 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000003921 239.0
HFD1_k127_1778795_14 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000006162 234.0
HFD1_k127_1778795_15 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000001737 228.0
HFD1_k127_1778795_16 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000004881 216.0
HFD1_k127_1778795_17 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000003115 219.0
HFD1_k127_1778795_18 - - - - 0.0000000000000000000000000000000000000000000000000001152 187.0
HFD1_k127_1778795_19 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000009686 173.0
HFD1_k127_1778795_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 473.0
HFD1_k127_1778795_20 HNH nucleases - - - 0.0000000000000000000000000000000000000001568 152.0
HFD1_k127_1778795_21 Calcineurin-like phosphoesterase superfamily domain K03269 - 3.6.1.54 0.00000000000000000000000000000000005463 143.0
HFD1_k127_1778795_22 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000005224 101.0
HFD1_k127_1778795_23 - - - - 0.00000000000000000001828 94.0
HFD1_k127_1778795_24 DNA-sulfur modification-associated - - - 0.00000000000000000006098 102.0
HFD1_k127_1778795_26 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000003219 81.0
HFD1_k127_1778795_27 - - - - 0.0000000009147 65.0
HFD1_k127_1778795_28 Rhodanese Homology Domain - - - 0.00004389 46.0
HFD1_k127_1778795_29 Aminotransferase - - - 0.0003443 44.0
HFD1_k127_1778795_3 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 406.0
HFD1_k127_1778795_4 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 392.0
HFD1_k127_1778795_5 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 375.0
HFD1_k127_1778795_6 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 369.0
HFD1_k127_1778795_7 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 349.0
HFD1_k127_1778795_8 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 335.0
HFD1_k127_1778795_9 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 350.0
HFD1_k127_1791814_0 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 296.0
HFD1_k127_1791814_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004121 286.0
HFD1_k127_1791814_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000001915 119.0
HFD1_k127_1791814_3 sodium-dependent phosphate transmembrane transporter activity - - - 0.000000000007355 74.0
HFD1_k127_1808012_0 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 306.0
HFD1_k127_1808012_1 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001476 270.0
HFD1_k127_1808012_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001205 255.0
HFD1_k127_1808012_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000888 71.0
HFD1_k127_181528_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.316e-292 910.0
HFD1_k127_181528_1 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 4.868e-195 613.0
HFD1_k127_181528_10 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000000000000000001 138.0
HFD1_k127_181528_11 - - - - 0.0000000000000000000000001882 112.0
HFD1_k127_181528_2 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 487.0
HFD1_k127_181528_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 419.0
HFD1_k127_181528_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 326.0
HFD1_k127_181528_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 293.0
HFD1_k127_181528_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005658 256.0
HFD1_k127_181528_7 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004827 246.0
HFD1_k127_181528_8 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000001548 202.0
HFD1_k127_181528_9 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000008969 144.0
HFD1_k127_1821035_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 443.0
HFD1_k127_1821035_1 GPR1/FUN34/yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 311.0
HFD1_k127_1821035_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 302.0
HFD1_k127_1821035_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000626 218.0
HFD1_k127_1821035_4 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000009759 201.0
HFD1_k127_1821035_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000003036 199.0
HFD1_k127_1821035_6 AAA domain - - - 0.00000000000000000000000000000000000000008417 154.0
HFD1_k127_1821035_7 metallopeptidase activity K01186 - 3.2.1.18 0.00000000000000000000009725 106.0
HFD1_k127_1821035_8 DnaJ molecular chaperone homology domain - - - 0.0000000000007638 81.0
HFD1_k127_1821035_9 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.000001964 61.0
HFD1_k127_1835010_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000979 248.0
HFD1_k127_1835010_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000006758 220.0
HFD1_k127_1835010_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000004174 154.0
HFD1_k127_1848665_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 464.0
HFD1_k127_1848665_1 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 343.0
HFD1_k127_1848665_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 274.0
HFD1_k127_1848665_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008463 259.0
HFD1_k127_1848665_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000002166 205.0
HFD1_k127_1848665_5 Eukaryotic integral membrane protein (DUF1751) K09650 - 3.4.21.105 0.00000000000000000000000000000000000000000000002274 178.0
HFD1_k127_1848665_6 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein - - - 0.00004244 52.0
HFD1_k127_1874245_0 Phosphoglucomutase K01835 - 5.4.2.2 4.409e-280 868.0
HFD1_k127_1874245_1 Belongs to the GPI family K01810 - 5.3.1.9 1.09e-275 855.0
HFD1_k127_1874245_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 2.015e-262 822.0
HFD1_k127_1874245_3 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.711e-197 626.0
HFD1_k127_1874245_4 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 353.0
HFD1_k127_1874245_5 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.000006587 48.0
HFD1_k127_1877151_0 Psort location CytoplasmicMembrane, score - - - 1.618e-246 782.0
HFD1_k127_1877151_1 Psort location Cytoplasmic, score K03518,K20446 - 1.17.1.5,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000001922 209.0
HFD1_k127_1877151_2 xanthine dehydrogenase activity K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000007239 190.0
HFD1_k127_1888552_0 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004873 280.0
HFD1_k127_1888552_1 Belongs to the OprB family K07267 - - 0.00000000000000000000000000000000000000000000000000000007859 211.0
HFD1_k127_1888552_2 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000004127 174.0
HFD1_k127_1888552_3 Ion transport 2 domain protein - - - 0.000000000000000000000000000000000000000001202 165.0
HFD1_k127_1888552_4 Oxygen tolerance - - - 0.00000000000000000000000000000000000000006191 169.0
HFD1_k127_1906313_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 451.0
HFD1_k127_1906313_1 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
HFD1_k127_1906313_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000009754 185.0
HFD1_k127_1906313_3 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000006738 153.0
HFD1_k127_1906313_4 Domain of unknown function (DUF4416) - - - 0.000000000000000000000005053 102.0
HFD1_k127_1906313_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000001433 85.0
HFD1_k127_1919690_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 606.0
HFD1_k127_1919690_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 401.0
HFD1_k127_1919690_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001445 270.0
HFD1_k127_1919690_3 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001111 241.0
HFD1_k127_1925162_0 Conserved region in glutamate synthase - - - 4.29e-231 726.0
HFD1_k127_1925162_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.917e-218 688.0
HFD1_k127_1925162_10 Clostripain family - - - 0.0000000000000000001412 104.0
HFD1_k127_1925162_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 583.0
HFD1_k127_1925162_3 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 542.0
HFD1_k127_1925162_4 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 459.0
HFD1_k127_1925162_5 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 433.0
HFD1_k127_1925162_6 ANTAR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005706 250.0
HFD1_k127_1925162_7 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000001217 251.0
HFD1_k127_1925162_8 LUD domain - - - 0.0000000000000000000000000000000000000000000000000000000002041 209.0
HFD1_k127_1925162_9 ANTAR - - - 0.00000000000000000000000000000000000000000000001403 184.0
HFD1_k127_1943230_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 363.0
HFD1_k127_1943230_1 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 355.0
HFD1_k127_1943230_2 AraC-like ligand binding domain - - - 0.0000000000000000000000000002607 118.0
HFD1_k127_1943230_3 acid phosphatase activity - - - 0.000000000000000000000000001205 118.0
HFD1_k127_1943230_4 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0003497 47.0
HFD1_k127_1943620_0 Type II and III secretion system protein K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 499.0
HFD1_k127_1943620_1 Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006369 284.0
HFD1_k127_1943620_2 Flp Fap pilin component K02651 - - 0.000006884 49.0
HFD1_k127_1951822_0 PD-(D/E)XK nuclease superfamily - - - 5.231e-260 835.0
HFD1_k127_1951822_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000005354 168.0
HFD1_k127_1951822_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000005177 102.0
HFD1_k127_1951822_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000003897 96.0
HFD1_k127_1951822_4 TIGRFAM DNA binding domain, excisionase family - - - 0.00008658 49.0
HFD1_k127_1958013_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 429.0
HFD1_k127_1958013_1 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 353.0
HFD1_k127_1958013_2 transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000613 199.0
HFD1_k127_1958013_3 Glutathione peroxidase - - - 0.00000000000000000000000000000000009652 139.0
HFD1_k127_1958013_4 TIGRFAM MoaD family protein K03636 - - 0.00000000000000000000000001262 111.0
HFD1_k127_1958013_5 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000006486 87.0
HFD1_k127_1961862_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 535.0
HFD1_k127_1961862_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 354.0
HFD1_k127_1961862_2 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000001268 143.0
HFD1_k127_1962544_0 response regulator receiver K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 393.0
HFD1_k127_1962544_1 GAF domain - - - 0.00000000000000000000000000000001834 141.0
HFD1_k127_1962544_2 diguanylate cyclase - - - 0.00000000001078 75.0
HFD1_k127_1963954_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 597.0
HFD1_k127_1963954_1 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 479.0
HFD1_k127_1963954_2 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 417.0
HFD1_k127_1963954_3 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000001036 226.0
HFD1_k127_1963954_4 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000007862 126.0
HFD1_k127_1964571_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.235e-229 726.0
HFD1_k127_1964571_1 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000002336 175.0
HFD1_k127_1964571_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000002752 74.0
HFD1_k127_1968136_0 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 349.0
HFD1_k127_1968136_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 316.0
HFD1_k127_1968136_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000001739 220.0
HFD1_k127_1968136_3 TRAP transporter, 4TM 12TM fusion protein - - - 0.000000000000001731 79.0
HFD1_k127_1968136_4 Transporter - - - 0.000000000009172 68.0
HFD1_k127_1968495_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.567e-270 852.0
HFD1_k127_1968495_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 591.0
HFD1_k127_1968495_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 405.0
HFD1_k127_1968495_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 342.0
HFD1_k127_1968495_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000003848 205.0
HFD1_k127_1968495_5 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000000000000000000000000000539 164.0
HFD1_k127_1968495_6 - - - - 0.00000000000000000000000000000001306 132.0
HFD1_k127_1968495_7 Thioredoxin-like - - - 0.0000000000000000000000001359 114.0
HFD1_k127_1968495_8 Helix-turn-helix domain K15539 - - 0.0000000000000000000002319 109.0
HFD1_k127_1968495_9 shape-determining protein MreD K03571 - - 0.0000001032 61.0
HFD1_k127_2000222_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1114.0
HFD1_k127_2000222_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 3.126e-203 651.0
HFD1_k127_2000222_2 xanthine dehydrogenase activity K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 377.0
HFD1_k127_2000222_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 335.0
HFD1_k127_2000222_4 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000004821 246.0
HFD1_k127_2000222_5 Single Cache domain 2 K03406 - - 0.000000000000000000000000000000000000000000000619 172.0
HFD1_k127_2029403_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 563.0
HFD1_k127_2029403_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 498.0
HFD1_k127_2029403_2 MgtE intracellular - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 415.0
HFD1_k127_2029403_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 355.0
HFD1_k127_2029403_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 295.0
HFD1_k127_2029403_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000001569 255.0
HFD1_k127_2029403_6 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000115 115.0
HFD1_k127_2029403_7 - - - - 0.0000000000000000000009323 103.0
HFD1_k127_2029403_8 sequence-specific DNA binding - - - 0.00000000000000000004646 91.0
HFD1_k127_2029403_9 TRANSCRIPTIONal - - - 0.000000006103 63.0
HFD1_k127_2063363_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 377.0
HFD1_k127_2063363_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000002064 251.0
HFD1_k127_2063363_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000003422 232.0
HFD1_k127_2063363_3 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000001518 191.0
HFD1_k127_2063363_4 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000003485 129.0
HFD1_k127_2063363_5 YtxH-like protein - - - 0.000000000000000000000000005842 113.0
HFD1_k127_2063363_6 Smr domain - - - 0.0000000000000000000000001493 108.0
HFD1_k127_2063363_7 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000005766 105.0
HFD1_k127_2072912_0 - - - - 1.307e-230 726.0
HFD1_k127_2072912_1 Domain of Unknown Function (DUF748) - - - 0.000000006923 60.0
HFD1_k127_2101897_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 340.0
HFD1_k127_2101897_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002734 266.0
HFD1_k127_2101897_2 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000007324 207.0
HFD1_k127_2101897_3 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000001006 207.0
HFD1_k127_2101897_4 Domain of unknown function (DUF4392) - - - 0.000000000000000000000000000000000000000000000000006491 192.0
HFD1_k127_2101897_5 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000002713 132.0
HFD1_k127_2103431_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 520.0
HFD1_k127_2103431_1 FCD K05799 - - 0.00000000000000000000000000000000001768 141.0
HFD1_k127_2103431_2 - - - - 0.0000000000000001617 80.0
HFD1_k127_211073_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003689 274.0
HFD1_k127_211073_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000001539 212.0
HFD1_k127_211073_2 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000001893 134.0
HFD1_k127_211073_3 PLD-like domain - - - 0.000000000000000000000000008354 116.0
HFD1_k127_212103_0 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 496.0
HFD1_k127_212103_1 GIY-YIG type nucleases (URI domain) K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000001754 213.0
HFD1_k127_212103_2 PFAM CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000005859 186.0
HFD1_k127_2123214_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 289.0
HFD1_k127_2123214_1 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000005434 234.0
HFD1_k127_2123214_2 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000005554 212.0
HFD1_k127_2123214_3 protein secretion K21449 - - 0.0005136 48.0
HFD1_k127_2145571_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 506.0
HFD1_k127_2145571_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K00605,K18847 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.1,2.1.2.10,2.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 443.0
HFD1_k127_214761_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 7.121e-196 627.0
HFD1_k127_214761_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 440.0
HFD1_k127_214761_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 430.0
HFD1_k127_214761_3 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000009052 160.0
HFD1_k127_214761_4 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000000006686 118.0
HFD1_k127_2168269_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 334.0
HFD1_k127_2168269_1 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000001189 143.0
HFD1_k127_2168269_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000001737 136.0
HFD1_k127_2169213_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000461 255.0
HFD1_k127_2169213_1 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000004745 127.0
HFD1_k127_2169213_2 - - - - 0.0002194 53.0
HFD1_k127_2176175_0 Belongs to the enoyl-CoA hydratase isomerase family K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 2.81e-259 812.0
HFD1_k127_2176175_1 AMP-binding enzyme K01897 - 6.2.1.3 6.634e-242 760.0
HFD1_k127_2176175_10 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 259.0
HFD1_k127_2176175_11 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000959 150.0
HFD1_k127_2176175_2 PFAM 2-nitropropane dioxygenase NPD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 610.0
HFD1_k127_2176175_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 561.0
HFD1_k127_2176175_4 PFAM Extracellular ligand-binding receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 443.0
HFD1_k127_2176175_5 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 408.0
HFD1_k127_2176175_6 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 370.0
HFD1_k127_2176175_7 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 362.0
HFD1_k127_2176175_8 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 358.0
HFD1_k127_2176175_9 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 345.0
HFD1_k127_2176646_0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 294.0
HFD1_k127_2176646_1 Urea transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 314.0
HFD1_k127_2176646_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000003029 128.0
HFD1_k127_2176646_3 repeat-containing protein - - - 0.0008605 49.0
HFD1_k127_217824_0 FAD dependent oxidoreductase K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 433.0
HFD1_k127_217824_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 296.0
HFD1_k127_217824_2 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000006534 235.0
HFD1_k127_217824_3 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.000000000000000000000000000000005328 129.0
HFD1_k127_217824_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000107 79.0
HFD1_k127_217824_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000004107 57.0
HFD1_k127_219694_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 361.0
HFD1_k127_219694_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 363.0
HFD1_k127_219694_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000003162 225.0
HFD1_k127_2197160_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 446.0
HFD1_k127_2197160_1 Iron-containing alcohol dehydrogenase K13954,K19714 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.1,1.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 412.0
HFD1_k127_2197160_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 408.0
HFD1_k127_2197160_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000002387 213.0
HFD1_k127_2197160_4 UPF0391 membrane protein - - - 0.000000000007652 66.0
HFD1_k127_2197160_5 SPW repeat - - - 0.0001514 48.0
HFD1_k127_2208243_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 534.0
HFD1_k127_2208243_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 292.0
HFD1_k127_2208243_2 - - - - 0.0000000000000000000000000008639 123.0
HFD1_k127_2208243_3 Domain of unknown function (DUF4911) - - - 0.000000000008344 67.0
HFD1_k127_2208243_4 gas vesicle protein - - - 0.000000007581 59.0
HFD1_k127_2210031_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 395.0
HFD1_k127_2210031_1 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 296.0
HFD1_k127_2210031_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000002141 156.0
HFD1_k127_2210031_3 - - - - 0.0000000000000000000000000000000253 134.0
HFD1_k127_2225624_0 Bacterial type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 395.0
HFD1_k127_2225624_1 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 308.0
HFD1_k127_2225624_10 - - - - 0.00003421 55.0
HFD1_k127_2225624_11 general secretion pathway protein K02456,K02458,K02459,K10927 - - 0.0004985 49.0
HFD1_k127_2225624_2 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000006754 238.0
HFD1_k127_2225624_3 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000001156 201.0
HFD1_k127_2225624_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000005509 179.0
HFD1_k127_2225624_5 Pfam Response regulator receiver - - - 0.0000000000000000000000005046 109.0
HFD1_k127_2225624_6 pilus assembly protein PilW K02459 - - 0.00000000000000000005308 99.0
HFD1_k127_2225624_7 Fimbrial assembly protein (PilN) - - - 0.00000000002205 76.0
HFD1_k127_2225624_8 Type II secretion system (T2SS), protein M subtype b - - - 0.000001913 57.0
HFD1_k127_2225624_9 Prokaryotic N-terminal methylation motif K02457 - - 0.000003462 56.0
HFD1_k127_2230729_0 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 424.0
HFD1_k127_2230729_1 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 306.0
HFD1_k127_2230729_2 TAT (twin-arginine translocation) pathway signal sequence K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009543 273.0
HFD1_k127_2230729_3 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
HFD1_k127_2230729_4 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000009721 219.0
HFD1_k127_2230729_5 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.000000000000002613 80.0
HFD1_k127_2233488_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1413.0
HFD1_k127_2233488_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 607.0
HFD1_k127_2233488_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000353 252.0
HFD1_k127_2233488_3 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000009567 242.0
HFD1_k127_2233488_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000428 230.0
HFD1_k127_2233488_5 transferase activity, transferring glycosyl groups - - - 0.000007568 55.0
HFD1_k127_2244040_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 387.0
HFD1_k127_2244040_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003303 264.0
HFD1_k127_2244040_2 Protein of unknown function (DUF3309) - - - 0.00000000000000008255 80.0
HFD1_k127_2271191_0 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 469.0
HFD1_k127_2271191_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000002704 184.0
HFD1_k127_2271191_2 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000282 147.0
HFD1_k127_2271191_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000002625 140.0
HFD1_k127_2271191_4 PFAM response regulator receiver - - - 0.000000000000000000003958 95.0
HFD1_k127_2271191_5 Multidrug transporter - - - 0.00001213 51.0
HFD1_k127_2271191_6 - - - - 0.0002145 49.0
HFD1_k127_2300888_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 301.0
HFD1_k127_2300888_1 PFAM Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001507 266.0
HFD1_k127_2300888_2 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008169 259.0
HFD1_k127_2300888_3 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000042 250.0
HFD1_k127_2300888_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002156 250.0
HFD1_k127_2300888_5 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000004138 227.0
HFD1_k127_2309228_0 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 587.0
HFD1_k127_2309228_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 349.0
HFD1_k127_2309228_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 342.0
HFD1_k127_2309228_3 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 329.0
HFD1_k127_2309228_4 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 320.0
HFD1_k127_2309228_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003483 289.0
HFD1_k127_2309228_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000001776 215.0
HFD1_k127_2317825_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 498.0
HFD1_k127_2317825_1 Protein of unknown function (DUF933) K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 313.0
HFD1_k127_2317825_10 Pfam:DUF479 - - - 0.000000000000000000000000000000000000000000000000000000007348 204.0
HFD1_k127_2317825_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000004171 179.0
HFD1_k127_2317825_12 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.000000000000000000000000000000000000000000000004754 175.0
HFD1_k127_2317825_13 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000002449 176.0
HFD1_k127_2317825_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000007986 159.0
HFD1_k127_2317825_15 Lipocalin-like domain - - - 0.000000000000000000000000000000000000007235 152.0
HFD1_k127_2317825_16 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000001359 132.0
HFD1_k127_2317825_2 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 304.0
HFD1_k127_2317825_3 iron-sulfur cluster-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 303.0
HFD1_k127_2317825_4 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 296.0
HFD1_k127_2317825_5 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 297.0
HFD1_k127_2317825_6 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001112 279.0
HFD1_k127_2317825_7 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004143 240.0
HFD1_k127_2317825_8 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000004644 212.0
HFD1_k127_2317825_9 electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000143 209.0
HFD1_k127_2326942_0 mannitol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 350.0
HFD1_k127_2326942_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 312.0
HFD1_k127_2326942_2 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000004438 102.0
HFD1_k127_23493_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 610.0
HFD1_k127_23493_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 435.0
HFD1_k127_23493_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 432.0
HFD1_k127_23493_3 Belongs to the GarS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 340.0
HFD1_k127_23493_4 aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 317.0
HFD1_k127_23493_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000001728 147.0
HFD1_k127_23493_6 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000001584 62.0
HFD1_k127_23493_7 GAF domain - - - 0.0001137 51.0
HFD1_k127_236847_0 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001984 282.0
HFD1_k127_236847_1 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000002419 243.0
HFD1_k127_236847_2 Dodecin K09165 - - 0.0000000000000000000008028 96.0
HFD1_k127_2434661_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 460.0
HFD1_k127_2434661_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 381.0
HFD1_k127_243573_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 446.0
HFD1_k127_243573_1 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 426.0
HFD1_k127_243573_2 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 400.0
HFD1_k127_243573_3 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003862 261.0
HFD1_k127_243573_4 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000011 203.0
HFD1_k127_243573_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000001796 193.0
HFD1_k127_243573_6 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000004035 149.0
HFD1_k127_243573_7 Pfam Response regulator receiver - - - 0.0000000000000000000000002427 110.0
HFD1_k127_2437059_0 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 512.0
HFD1_k127_2437059_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009871 245.0
HFD1_k127_2437059_2 - - - - 0.0000000000004513 79.0
HFD1_k127_2439996_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 6.962e-246 774.0
HFD1_k127_2439996_1 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 510.0
HFD1_k127_2439996_2 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000004615 228.0
HFD1_k127_2439996_3 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000002434 212.0
HFD1_k127_2439996_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000008428 176.0
HFD1_k127_2439996_5 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00192,K00193 - 1.2.7.4 0.00000000000000000000000000000000000000000004305 164.0
HFD1_k127_2439996_6 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000008198 147.0
HFD1_k127_2439996_7 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000005937 114.0
HFD1_k127_2440788_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 456.0
HFD1_k127_2440788_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 387.0
HFD1_k127_2440788_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 323.0
HFD1_k127_2440788_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 294.0
HFD1_k127_2440788_5 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000003284 118.0
HFD1_k127_2440788_6 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.0000000000000000000002736 102.0
HFD1_k127_2440788_7 Regulatory protein, FmdB family - - - 0.0000000000000003907 81.0
HFD1_k127_2440788_8 sequence-specific DNA binding K18830 - - 0.000000000000005922 79.0
HFD1_k127_2440788_9 nuclease activity K06218,K07334 - - 0.000000003351 60.0
HFD1_k127_2450854_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000001419 227.0
HFD1_k127_2450854_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000001732 222.0
HFD1_k127_2461229_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.447e-197 629.0
HFD1_k127_2461229_1 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 392.0
HFD1_k127_2461229_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000004891 229.0
HFD1_k127_2461229_3 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000007511 89.0
HFD1_k127_2463207_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 467.0
HFD1_k127_2463207_1 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 432.0
HFD1_k127_2463207_10 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000521 170.0
HFD1_k127_2463207_11 sam-dependent methyltransferase - - - 0.0000000000000142 82.0
HFD1_k127_2463207_12 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000001123 63.0
HFD1_k127_2463207_2 Beta-eliminating lyase K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 338.0
HFD1_k127_2463207_3 glycosyl transferase family 39 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 315.0
HFD1_k127_2463207_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 306.0
HFD1_k127_2463207_5 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001403 272.0
HFD1_k127_2463207_6 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000823 267.0
HFD1_k127_2463207_7 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003543 271.0
HFD1_k127_2463207_8 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004719 251.0
HFD1_k127_2463207_9 glycosyl transferase family 39 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000001466 253.0
HFD1_k127_2466357_0 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 360.0
HFD1_k127_2466357_1 - - - - 0.0000000000000000000000000001738 119.0
HFD1_k127_2504825_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.702e-246 773.0
HFD1_k127_2504825_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 599.0
HFD1_k127_2504825_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 486.0
HFD1_k127_2504825_3 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000006991 154.0
HFD1_k127_2506860_0 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005587 258.0
HFD1_k127_2506860_1 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000000000001384 156.0
HFD1_k127_2506860_2 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000000000000000003271 153.0
HFD1_k127_2506860_3 Phospholipid methyltransferase - - - 0.00000000000000000329 93.0
HFD1_k127_2514024_0 PFAM Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004104 280.0
HFD1_k127_2514024_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000001263 144.0
HFD1_k127_2514024_2 beta-lactamase domain protein - - - 0.0000000000000000000000000003046 121.0
HFD1_k127_2514024_3 Metallo-beta-lactamase superfamily - - - 0.000000000000003032 87.0
HFD1_k127_2523863_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 529.0
HFD1_k127_2523863_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 387.0
HFD1_k127_2523863_2 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000003384 139.0
HFD1_k127_2533187_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.005e-255 795.0
HFD1_k127_2533187_1 CoA binding domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 621.0
HFD1_k127_2533187_2 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 364.0
HFD1_k127_2533187_3 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 321.0
HFD1_k127_2533187_4 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.0000000000000000000000000000000000000000000000000000000000003773 219.0
HFD1_k127_2533187_5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - GO:0000166,GO:0000959,GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006970,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009451,GO:0009628,GO:0009631,GO:0009651,GO:0009791,GO:0009845,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034336,GO:0034641,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043242,GO:0043244,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090351,GO:0097159,GO:0097367,GO:1900864,GO:1901265,GO:1901360,GO:1901363,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000004637 125.0
HFD1_k127_2533187_6 YCII-related domain - - - 0.00000000000000001044 85.0
HFD1_k127_2541050_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.637e-229 720.0
HFD1_k127_2541050_1 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000006214 210.0
HFD1_k127_2541050_2 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000319 66.0
HFD1_k127_2552860_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1204.0
HFD1_k127_2552860_1 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 4.878e-217 685.0
HFD1_k127_2552860_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 8.594e-211 664.0
HFD1_k127_2552860_3 Phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000009281 236.0
HFD1_k127_2552860_4 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.00000000000000000000000000000000000001096 147.0
HFD1_k127_258574_0 PFAM Type II secretion system protein E K02283,K03609 - - 7.797e-197 623.0
HFD1_k127_258574_1 PFAM TadE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 505.0
HFD1_k127_258574_2 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 329.0
HFD1_k127_258574_3 PFAM type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 291.0
HFD1_k127_258574_4 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 285.0
HFD1_k127_258574_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000001389 205.0
HFD1_k127_258574_6 PFAM TadE family protein - - - 0.0000000000000000000000000000005068 126.0
HFD1_k127_258574_7 domain, Protein K15125,K21449 - - 0.000000000000000000000000003637 128.0
HFD1_k127_258574_8 Carboxylesterase family - - - 0.00000000000000000000004189 106.0
HFD1_k127_258574_9 Belongs to the peptidase S8 family K20276 - - 0.00000000000000000005083 105.0
HFD1_k127_261279_0 Protein involved in outer membrane biogenesis - - - 7.413e-211 690.0
HFD1_k127_261279_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 368.0
HFD1_k127_261279_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000009207 266.0
HFD1_k127_2615080_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 289.0
HFD1_k127_2615080_1 Putative cyclase - - - 0.00000000000000000000000000004053 119.0
HFD1_k127_2615080_2 membrane K07794 - - 0.000005945 49.0
HFD1_k127_2624725_0 symporter activity K11928,K14392 - - 1.737e-241 755.0
HFD1_k127_2624725_1 CBS domain containing protein K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 491.0
HFD1_k127_2624725_2 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000006993 146.0
HFD1_k127_2624725_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000009006 119.0
HFD1_k127_2667602_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 611.0
HFD1_k127_2667602_1 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 562.0
HFD1_k127_2667602_2 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 559.0
HFD1_k127_2667602_3 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 347.0
HFD1_k127_2667602_4 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000009615 228.0
HFD1_k127_2667602_5 radical SAM domain protein - - - 0.0000000001006 62.0
HFD1_k127_2689216_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 391.0
HFD1_k127_2689216_1 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 325.0
HFD1_k127_2689216_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003496 276.0
HFD1_k127_2689216_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000001385 201.0
HFD1_k127_2689216_4 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000002047 154.0
HFD1_k127_2695372_0 AAA family ATPase, CDC48 subfamily - - - 1.32e-207 662.0
HFD1_k127_2695372_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 476.0
HFD1_k127_2695372_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 304.0
HFD1_k127_2695372_3 COGs COG1144 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase delta subunit K00171,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000002263 209.0
HFD1_k127_2695372_4 Regulatory protein GntR HTH K05799 - - 0.0000000000000000000000000000000000004367 152.0
HFD1_k127_2695372_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000004073 114.0
HFD1_k127_2696491_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.778e-227 709.0
HFD1_k127_2696491_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.069e-226 710.0
HFD1_k127_2696491_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000004385 67.0
HFD1_k127_2696491_11 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000006543 57.0
HFD1_k127_2696491_2 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 593.0
HFD1_k127_2696491_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 319.0
HFD1_k127_2696491_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005737 265.0
HFD1_k127_2696491_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000008232 143.0
HFD1_k127_2696491_6 Polymer-forming cytoskeletal - - - 0.00000000000000000000000002279 113.0
HFD1_k127_2696491_7 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000005259 111.0
HFD1_k127_2696491_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000001332 98.0
HFD1_k127_2696491_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000001327 79.0
HFD1_k127_2712383_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 595.0
HFD1_k127_2712383_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004714 259.0
HFD1_k127_2712383_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006898 233.0
HFD1_k127_2712383_3 - - - - 0.00000000000000000000000000000000000000000000000000000000001619 214.0
HFD1_k127_2712383_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000001742 148.0
HFD1_k127_2712383_5 GntR family - - - 0.0000000000000000000000000000002752 132.0
HFD1_k127_2712383_6 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00009016 44.0
HFD1_k127_2725842_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.744e-320 1002.0
HFD1_k127_2725842_1 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 567.0
HFD1_k127_2746945_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.405e-316 979.0
HFD1_k127_2746945_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 417.0
HFD1_k127_2746945_10 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000001824 53.0
HFD1_k127_2746945_11 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00001102 49.0
HFD1_k127_2746945_12 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0005888 46.0
HFD1_k127_2746945_2 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 402.0
HFD1_k127_2746945_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 404.0
HFD1_k127_2746945_4 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 377.0
HFD1_k127_2746945_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 357.0
HFD1_k127_2746945_6 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 351.0
HFD1_k127_2746945_7 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 311.0
HFD1_k127_2746945_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005139 277.0
HFD1_k127_2746945_9 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000009668 79.0
HFD1_k127_2782656_0 COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 404.0
HFD1_k127_2782656_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000008401 177.0
HFD1_k127_2782656_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000004244 119.0
HFD1_k127_2786903_0 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 590.0
HFD1_k127_2786903_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 469.0
HFD1_k127_2786903_10 Rubrerythrin - - - 0.0000000000000000000000000000002466 125.0
HFD1_k127_2786903_12 FtsZ-dependent cytokinesis - - - 0.0000000000000002905 79.0
HFD1_k127_2786903_13 CAAX protease self-immunity K07052 - - 0.000000000001004 77.0
HFD1_k127_2786903_14 Short C-terminal domain K08982 - - 0.000000000009106 69.0
HFD1_k127_2786903_15 smart pdz dhr glgf - - - 0.000000002643 63.0
HFD1_k127_2786903_2 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 410.0
HFD1_k127_2786903_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 319.0
HFD1_k127_2786903_4 PFAM NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006697 276.0
HFD1_k127_2786903_5 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000001461 244.0
HFD1_k127_2786903_6 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000102 237.0
HFD1_k127_2786903_7 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000004848 157.0
HFD1_k127_2786903_8 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000159 152.0
HFD1_k127_2786903_9 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000000000000001748 129.0
HFD1_k127_2816926_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1234.0
HFD1_k127_2816926_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 9.707e-227 706.0
HFD1_k127_2816926_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 586.0
HFD1_k127_2816926_3 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 501.0
HFD1_k127_2816926_4 protein kinase activity - - - 0.00000000000000000000000000000000000000002644 165.0
HFD1_k127_2816926_5 Sporulation and spore germination - - - 0.00000000000000000000000000001964 126.0
HFD1_k127_2816926_6 membrane - - - 0.0000000000000000000000000001875 118.0
HFD1_k127_2816926_7 4Fe-4S dicluster domain - - - 0.000000000000005915 77.0
HFD1_k127_281895_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 582.0
HFD1_k127_281895_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 379.0
HFD1_k127_281895_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 331.0
HFD1_k127_281895_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 319.0
HFD1_k127_281895_4 cellulase activity - - - 0.000000000000000000001626 99.0
HFD1_k127_2837837_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.516e-268 847.0
HFD1_k127_2837837_1 Psort location CytoplasmicMembrane, score K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 549.0
HFD1_k127_2837837_2 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 392.0
HFD1_k127_2837837_3 LysR substrate binding domain K16135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 387.0
HFD1_k127_2837837_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 357.0
HFD1_k127_2837837_5 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002348 285.0
HFD1_k127_2837837_6 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000003193 266.0
HFD1_k127_2837837_7 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000003293 58.0
HFD1_k127_2837837_8 Tripartite tricarboxylate transporter TctA family - - - 0.0002677 44.0
HFD1_k127_284602_0 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 3.577e-207 654.0
HFD1_k127_284602_1 radical SAM domain protein K04034 - 1.21.98.3 1.645e-197 627.0
HFD1_k127_284602_2 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 438.0
HFD1_k127_284602_3 TIGRFAM hopanoid biosynthesis associated membrane protein HpnM K07323 - - 0.00000000000000000000000000000000000000000000000002466 187.0
HFD1_k127_2856259_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 431.0
HFD1_k127_2856259_1 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 353.0
HFD1_k127_2856259_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002418 246.0
HFD1_k127_2856259_3 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000001372 148.0
HFD1_k127_2856259_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000881 139.0
HFD1_k127_285707_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 490.0
HFD1_k127_285707_1 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008813 450.0
HFD1_k127_285707_2 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 289.0
HFD1_k127_2861250_0 carbon-monoxide dehydrogenase (ferredoxin) activity K00192,K02572,K02573,K14138 - 1.2.7.4,2.3.1.169 7.862e-315 980.0
HFD1_k127_2861250_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 9.11e-240 745.0
HFD1_k127_2861250_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 465.0
HFD1_k127_2861250_3 Pterin binding enzyme K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 339.0
HFD1_k127_2861250_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 319.0
HFD1_k127_2861250_5 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000006576 222.0
HFD1_k127_2861250_6 PFAM CO dehydrogenase beta subunit acetyl-CoA synthase epsilon subunit K00195,K03800 - 6.3.1.20 0.0000000000000000000000004689 107.0
HFD1_k127_2869478_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 394.0
HFD1_k127_2869478_1 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 355.0
HFD1_k127_2869478_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 309.0
HFD1_k127_2869478_3 transferase hexapeptide K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001734 278.0
HFD1_k127_2869478_4 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000106 177.0
HFD1_k127_2906032_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 521.0
HFD1_k127_2906032_1 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 435.0
HFD1_k127_2906032_2 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 334.0
HFD1_k127_2906032_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 329.0
HFD1_k127_2906032_4 PFAM FAD linked oxidase domain protein K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 329.0
HFD1_k127_293254_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 293.0
HFD1_k127_293254_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000001861 123.0
HFD1_k127_2939328_0 Flagellar basal body protein FlaE K02390 - - 0.000000000000000000000000000000000000000000000000000007056 198.0
HFD1_k127_3008820_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 428.0
HFD1_k127_3008820_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002477 218.0
HFD1_k127_3008820_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000004058 147.0
HFD1_k127_3008820_3 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000001781 107.0
HFD1_k127_3008820_4 Fe-S oxidoreductase - - - 0.000000002217 63.0
HFD1_k127_3008820_5 4Fe-4S binding domain - - - 0.000000004095 65.0
HFD1_k127_3021970_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000007991 221.0
HFD1_k127_3021970_1 (2R)-phospho-3-sulfolactate synthase (ComA) K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000002456 170.0
HFD1_k127_3021970_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000002521 140.0
HFD1_k127_3021970_3 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000003426 134.0
HFD1_k127_3021970_4 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000004216 139.0
HFD1_k127_3021970_5 anaerobic respiration - - - 0.00000000000000000000000991 110.0
HFD1_k127_3021970_6 Protein of unknown function (DUF1018) - - - 0.00009374 51.0
HFD1_k127_3030845_0 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 421.0
HFD1_k127_3030845_1 HEAT repeats K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 302.0
HFD1_k127_3030845_2 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000428 230.0
HFD1_k127_3030845_3 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.00000000000000000000000000000000000000000000000000142 184.0
HFD1_k127_3030845_4 Hydrolase - - - 0.00000000000000000000000000000000000003163 153.0
HFD1_k127_3030845_5 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000001628 118.0
HFD1_k127_3030845_6 Nitrate reductase gamma subunit - - - 0.00000000000000003079 92.0
HFD1_k127_3030845_7 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000001395 55.0
HFD1_k127_3035152_0 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 328.0
HFD1_k127_3035152_1 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002668 280.0
HFD1_k127_3035152_2 Fumarate reductase succinate dehydrogenase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002968 276.0
HFD1_k127_3035152_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000008566 222.0
HFD1_k127_3035152_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000001576 144.0
HFD1_k127_3035152_5 COGs COG4087 Soluble P-type ATPase - - - 0.000000000000000000000001627 109.0
HFD1_k127_3035152_6 - - - - 0.00000000000001068 76.0
HFD1_k127_3035152_7 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000003333 74.0
HFD1_k127_3058326_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
HFD1_k127_3058326_1 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000006445 104.0
HFD1_k127_3058326_2 histidine kinase A domain protein - - - 0.000000000000001182 82.0
HFD1_k127_3064623_0 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000373 152.0
HFD1_k127_3064623_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000002603 101.0
HFD1_k127_3064623_2 Protein of unknown function (DUF3309) - - - 0.0000000000000004046 78.0
HFD1_k127_308280_0 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 345.0
HFD1_k127_308280_1 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 264.0
HFD1_k127_308280_2 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000004059 165.0
HFD1_k127_3097746_0 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 295.0
HFD1_k127_3097746_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007943 255.0
HFD1_k127_3097746_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000312 244.0
HFD1_k127_3097746_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000007525 217.0
HFD1_k127_3097746_4 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000002928 205.0
HFD1_k127_3097746_5 sequence-specific DNA binding K18830 - - 0.00000000000000000000000000000000000001143 148.0
HFD1_k127_3097746_6 Transposase IS200 like - - - 0.00000000000000000000000000000000000002918 147.0
HFD1_k127_3097746_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000005383 114.0
HFD1_k127_3097746_8 chlorophyll binding - - - 0.00000000000000000005448 104.0
HFD1_k127_3109748_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 1.047e-280 870.0
HFD1_k127_3109748_1 growth of symbiont in host cell K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 515.0
HFD1_k127_3109748_2 Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 282.0
HFD1_k127_3125058_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 3.73e-253 791.0
HFD1_k127_3125058_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 469.0
HFD1_k127_3125058_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 464.0
HFD1_k127_3125058_3 - - - - 0.00000000000000000000000000000002655 130.0
HFD1_k127_3128456_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 523.0
HFD1_k127_3128456_1 Pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 318.0
HFD1_k127_3128456_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001848 199.0
HFD1_k127_3128456_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000002949 167.0
HFD1_k127_3128456_4 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000002982 155.0
HFD1_k127_3128456_5 spore germination K03605 - - 0.0000000000000000000000000000000000003966 144.0
HFD1_k127_3128456_6 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000004443 139.0
HFD1_k127_3128456_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00003926 48.0
HFD1_k127_3140796_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 518.0
HFD1_k127_3140796_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 370.0
HFD1_k127_3140796_2 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000003297 231.0
HFD1_k127_3140796_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000003036 204.0
HFD1_k127_3140796_4 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000154 205.0
HFD1_k127_3151880_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.986e-253 793.0
HFD1_k127_3151880_1 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 496.0
HFD1_k127_3151880_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 475.0
HFD1_k127_3151880_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 445.0
HFD1_k127_3151880_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 420.0
HFD1_k127_3151880_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 326.0
HFD1_k127_3151880_6 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007269 279.0
HFD1_k127_3151880_7 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003541 274.0
HFD1_k127_3151880_8 Transposase for insertion sequence element - - - 0.00000000000000000000000006366 110.0
HFD1_k127_3151880_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000003389 98.0
HFD1_k127_3152933_0 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000033 276.0
HFD1_k127_3152933_1 Domain of unknown function (DUF3842) - - - 0.000000000000000000000000000000000000000002148 160.0
HFD1_k127_3152933_2 PFAM Cobalt transport protein K02008 - - 0.00000000000000000000000000000001199 138.0
HFD1_k127_3152933_3 cobalt ion transport K02009 - - 0.0000000000000000000000009184 107.0
HFD1_k127_3152933_4 Predicted RNA-binding protein - - - 0.000000000000000007208 85.0
HFD1_k127_3160928_0 PFAM magnesium chelatase ChlI subunit K07391 - - 1.453e-224 707.0
HFD1_k127_3160928_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 561.0
HFD1_k127_3160928_2 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 293.0
HFD1_k127_3163348_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.219e-248 781.0
HFD1_k127_3163348_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 520.0
HFD1_k127_3163348_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000006398 214.0
HFD1_k127_3163348_11 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000001437 205.0
HFD1_k127_3163348_12 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000001145 175.0
HFD1_k127_3163348_13 Pyridoxamine 5'-phosphate oxidase K11473 - - 0.0000000000000000314 82.0
HFD1_k127_3163348_14 Protein of unknown function (DUF465) K09794 - - 0.0000000005691 63.0
HFD1_k127_3163348_2 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 439.0
HFD1_k127_3163348_3 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 359.0
HFD1_k127_3163348_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 351.0
HFD1_k127_3163348_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 299.0
HFD1_k127_3163348_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002117 264.0
HFD1_k127_3163348_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002771 241.0
HFD1_k127_3163348_8 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000007397 234.0
HFD1_k127_3163348_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000267 222.0
HFD1_k127_316957_0 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000001209 205.0
HFD1_k127_316957_1 carbamate kinase K00926 - 2.7.2.2 0.00000000000000000000000000000000000729 139.0
HFD1_k127_316957_2 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000001052 109.0
HFD1_k127_316957_3 - - - - 0.00000000000000000004643 106.0
HFD1_k127_316957_4 Protein of unknown function (DUF3243) - - - 0.00000003641 59.0
HFD1_k127_3183267_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1453.0
HFD1_k127_3183267_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.734e-300 932.0
HFD1_k127_3183267_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.415e-254 796.0
HFD1_k127_3183267_3 4 iron, 4 sulfur cluster binding K03522,K13795,K15511 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000000000005104 253.0
HFD1_k127_3183267_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000001108 124.0
HFD1_k127_3183267_5 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000001589 105.0
HFD1_k127_3200272_0 AcrB/AcrD/AcrF family K03296,K19594 - - 1.888e-308 960.0
HFD1_k127_3200272_1 outer membrane efflux - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 602.0
HFD1_k127_3200272_2 Biotin-lipoyl like K19595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 429.0
HFD1_k127_3232038_0 Glyoxalase-like domain K01759,K08234 - 4.4.1.5 0.000000000000000000000000000000000000000000003594 166.0
HFD1_k127_3232038_1 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000007377 160.0
HFD1_k127_3232038_2 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000001364 149.0
HFD1_k127_3232038_3 SMART helix-turn-helix domain protein K15539 - - 0.00000000003097 72.0
HFD1_k127_3232038_4 M61 glycyl aminopeptidase - - - 0.000004399 49.0
HFD1_k127_3232038_5 DnaJ domain protein K05516 - - 0.00003299 53.0
HFD1_k127_3234355_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001109 293.0
HFD1_k127_3234355_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000387 237.0
HFD1_k127_3234355_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000002389 169.0
HFD1_k127_3234355_3 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' - - - 0.00000000000000000000000000000000008031 142.0
HFD1_k127_3238569_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000375 270.0
HFD1_k127_3238569_1 PFAM Roadblock LC7 - - - 0.00000000000000000000000000000004069 130.0
HFD1_k127_3238569_2 Tetratricopeptide repeats - - - 0.000000000000000001161 97.0
HFD1_k127_3238569_3 Tetratricopeptide repeat - - - 0.0000000000000003361 89.0
HFD1_k127_3239593_0 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 330.0
HFD1_k127_3239593_1 - - - - 0.00000000000000000000000000000000000000000009217 166.0
HFD1_k127_3239593_2 - - - - 0.0000000000000000000000000000001082 128.0
HFD1_k127_3239593_3 Tetratricopeptide repeat - - - 0.00000000003235 68.0
HFD1_k127_3272875_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1186.0
HFD1_k127_3272875_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1083.0
HFD1_k127_3272875_2 Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000000000233 159.0
HFD1_k127_3272875_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000008868 134.0
HFD1_k127_3272875_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000004606 86.0
HFD1_k127_3272875_5 - - - - 0.000000000000007783 78.0
HFD1_k127_3273180_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 5.955e-228 724.0
HFD1_k127_3273180_1 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000302 214.0
HFD1_k127_3289796_0 Belongs to the carbamoyltransferase HypF family K04656 - - 4.635e-267 842.0
HFD1_k127_3289796_1 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000241 209.0
HFD1_k127_3289796_2 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000002059 139.0
HFD1_k127_3289796_3 HupF/HypC family K04653 - - 0.000000000000000001956 87.0
HFD1_k127_3292660_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 294.0
HFD1_k127_3292660_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
HFD1_k127_3292660_2 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003568 244.0
HFD1_k127_3292660_3 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000002018 235.0
HFD1_k127_3292660_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000381 221.0
HFD1_k127_3292660_5 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000001016 215.0
HFD1_k127_3292660_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000003569 141.0
HFD1_k127_3292660_7 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000004349 136.0
HFD1_k127_3293379_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 7.436e-246 786.0
HFD1_k127_3293379_1 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 483.0
HFD1_k127_3293379_2 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 310.0
HFD1_k127_3293379_3 - - - - 0.000002831 53.0
HFD1_k127_3293379_4 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00006026 50.0
HFD1_k127_3308767_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.197e-280 870.0
HFD1_k127_3308767_1 extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 345.0
HFD1_k127_3308767_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006855 279.0
HFD1_k127_3308767_3 Histidine kinase K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000001502 99.0
HFD1_k127_3308767_4 - - - - 0.0000009537 55.0
HFD1_k127_3340180_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 529.0
HFD1_k127_3340180_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 438.0
HFD1_k127_3340180_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 325.0
HFD1_k127_3344391_0 ATP-grasp domain K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 579.0
HFD1_k127_3344391_1 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 566.0
HFD1_k127_3344391_10 Thioesterase superfamily protein - - - 0.0000000000000000000000000003838 119.0
HFD1_k127_3344391_11 response regulator K13599 - - 0.0000000000000000008093 90.0
HFD1_k127_3344391_12 Outer membrane lipoprotein - - - 0.00000000000000009426 92.0
HFD1_k127_3344391_2 CoA-ligase K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 468.0
HFD1_k127_3344391_3 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 273.0
HFD1_k127_3344391_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002706 274.0
HFD1_k127_3344391_5 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000316 263.0
HFD1_k127_3344391_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000005435 263.0
HFD1_k127_3344391_7 NlpC/P60 family K19223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006683 252.0
HFD1_k127_3344391_8 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004795 244.0
HFD1_k127_3344391_9 flavin reductase - - - 0.0000000000000000000000000000000000000000000000000000000002024 208.0
HFD1_k127_3355033_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.44e-228 723.0
HFD1_k127_3355033_1 FAD binding domain - - - 6.719e-197 621.0
HFD1_k127_3355033_2 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000002576 194.0
HFD1_k127_3355033_3 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000003774 179.0
HFD1_k127_3355033_4 PFAM Cysteine-rich region, CCG K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000001063 93.0
HFD1_k127_3370360_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.138e-252 790.0
HFD1_k127_3370360_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 517.0
HFD1_k127_3370360_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 402.0
HFD1_k127_3370360_3 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 328.0
HFD1_k127_3370360_4 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 320.0
HFD1_k127_3370360_5 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000002812 162.0
HFD1_k127_3370360_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000009127 142.0
HFD1_k127_3370360_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000001015 100.0
HFD1_k127_3370360_8 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000002835 87.0
HFD1_k127_3370360_9 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000002436 75.0
HFD1_k127_3379613_0 PFAM OsmC family protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 532.0
HFD1_k127_3379613_1 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 362.0
HFD1_k127_3379613_2 Membrane - - - 0.00000000000000000000000000000002335 131.0
HFD1_k127_3379613_4 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000003266 66.0
HFD1_k127_3384734_0 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 432.0
HFD1_k127_3384734_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 357.0
HFD1_k127_3384734_2 - - - - 0.0001677 48.0
HFD1_k127_3407726_0 Belongs to the OprB family K07267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 298.0
HFD1_k127_3407726_1 outer membrane porin, OprD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001257 273.0
HFD1_k127_3407726_2 - - - - 0.000000000000000008197 85.0
HFD1_k127_3419104_0 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 334.0
HFD1_k127_3419104_1 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000000000000001443 158.0
HFD1_k127_3419104_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000002517 99.0
HFD1_k127_3419104_3 Protein of unknown function (DUF1722) - - - 0.0000000000003643 71.0
HFD1_k127_3419104_4 Ankyrin repeat - - - 0.0000000001348 73.0
HFD1_k127_3419104_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.00007066 46.0
HFD1_k127_3427541_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 544.0
HFD1_k127_3427541_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 349.0
HFD1_k127_3427541_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000002752 229.0
HFD1_k127_3427541_3 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000477 224.0
HFD1_k127_3427541_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000007614 188.0
HFD1_k127_3427541_5 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000001235 183.0
HFD1_k127_3427541_6 QueT transporter K16928 - - 0.00000000000000000000000000000000000000000000002069 179.0
HFD1_k127_3427541_7 PFAM ABC transporter related K16786,K16787 - - 0.00000000000000000000000000000000000000000000006199 173.0
HFD1_k127_3427541_8 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.000000000000000000000006513 111.0
HFD1_k127_3427541_9 phosphorelay signal transduction system K03974 - - 0.00000000000006424 77.0
HFD1_k127_3429886_0 DDE_Tnp_1-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 469.0
HFD1_k127_3429886_1 Transposase DDE domain - - - 0.0000000000000000000000000000000001305 143.0
HFD1_k127_3434418_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 535.0
HFD1_k127_3434418_1 PFAM D-galactarate dehydratase Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 394.0
HFD1_k127_3453311_0 PAS domain K13598 - 2.7.13.3 8.498e-221 707.0
HFD1_k127_3453311_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000001614 213.0
HFD1_k127_3471533_0 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 466.0
HFD1_k127_3471533_1 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000168 271.0
HFD1_k127_3471533_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000006707 229.0
HFD1_k127_3471533_3 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000003038 198.0
HFD1_k127_3481855_0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 K03738 - 1.2.7.5 2.408e-218 691.0
HFD1_k127_3481855_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 437.0
HFD1_k127_3481855_2 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 387.0
HFD1_k127_3481855_3 dTDP-4-dehydrorhamnose 3,5-epimerase activity - - - 0.000000000000000000000000000000000000000000000009755 174.0
HFD1_k127_3493886_0 Belongs to the aldehyde dehydrogenase family - - - 7.465e-207 654.0
HFD1_k127_3493886_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 394.0
HFD1_k127_3493886_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 327.0
HFD1_k127_3493886_3 sam-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002559 237.0
HFD1_k127_3493886_4 PFAM regulatory protein TetR K16137 - - 0.00000000000000000000000000000000000000002338 160.0
HFD1_k127_3493886_5 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.000000000000000000000000000000003545 131.0
HFD1_k127_3493886_6 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000000000000000000000000008691 137.0
HFD1_k127_3493886_7 TIGRFAM C_GCAxxG_C_C family - - - 0.0000002899 57.0
HFD1_k127_3493886_8 4Fe-4S binding domain - - - 0.00002639 50.0
HFD1_k127_3497824_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 308.0
HFD1_k127_3497824_1 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001742 263.0
HFD1_k127_3497824_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000006826 160.0
HFD1_k127_3538521_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 288.0
HFD1_k127_3538521_1 ABC transporter, ATP-binding protein K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001477 277.0
HFD1_k127_3538521_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004717 265.0
HFD1_k127_3538521_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009928 264.0
HFD1_k127_3538521_4 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001072 252.0
HFD1_k127_3553628_0 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 6.553e-218 683.0
HFD1_k127_3553628_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 501.0
HFD1_k127_3553628_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 404.0
HFD1_k127_3553628_3 PFAM Saccharopine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 365.0
HFD1_k127_3553628_4 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.00000000000000000000000000000000000000000000005425 173.0
HFD1_k127_3553628_5 PFAM response regulator receiver - - - 0.00000000000000000000000000007835 119.0
HFD1_k127_3553872_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 537.0
HFD1_k127_3553872_1 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 467.0
HFD1_k127_3553872_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000008618 146.0
HFD1_k127_3578047_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 330.0
HFD1_k127_3578047_1 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000004902 192.0
HFD1_k127_3578047_2 NUDIX domain - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000000000000000000000000008723 159.0
HFD1_k127_3578047_3 Phospholipid methyltransferase - - - 0.000000000000000000007931 100.0
HFD1_k127_3578047_4 - - - - 0.000000000001281 69.0
HFD1_k127_3598467_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000006648 240.0
HFD1_k127_3598467_1 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000007781 233.0
HFD1_k127_3598467_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000008944 234.0
HFD1_k127_3598467_3 Putative ATP-dependant zinc protease - - - 0.00000000000000001124 89.0
HFD1_k127_3619181_0 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 357.0
HFD1_k127_3619181_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 329.0
HFD1_k127_3619181_2 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 333.0
HFD1_k127_3619181_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 338.0
HFD1_k127_3619181_4 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000004548 238.0
HFD1_k127_3619181_5 cell adhesion involved in biofilm formation K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000004495 205.0
HFD1_k127_3619181_6 (ABC) transporter K02050 - - 0.00000000000000000000000000000000000000000000000000000001834 222.0
HFD1_k127_3619181_7 (ABC) transporter K02051 - - 0.000000000000000000000000000000000000000005354 168.0
HFD1_k127_3619181_8 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000005609 80.0
HFD1_k127_366053_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.3e-228 719.0
HFD1_k127_366053_1 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 359.0
HFD1_k127_366483_0 DegT/DnrJ/EryC1/StrS aminotransferase family K20429 - 2.6.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 567.0
HFD1_k127_366483_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005215 226.0
HFD1_k127_366483_2 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000001131 165.0
HFD1_k127_366483_3 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000009613 116.0
HFD1_k127_366483_4 transferase activity, transferring amino-acyl groups - - - 0.0002447 52.0
HFD1_k127_3695436_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1128.0
HFD1_k127_3695436_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 310.0
HFD1_k127_3695436_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000004873 183.0
HFD1_k127_369591_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.189e-243 761.0
HFD1_k127_369591_1 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 297.0
HFD1_k127_369591_2 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009228 261.0
HFD1_k127_369591_3 Involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000006825 164.0
HFD1_k127_369591_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000003511 145.0
HFD1_k127_369591_5 GIY-YIG catalytic domain - - - 0.0000000000000000000000001977 108.0
HFD1_k127_369591_6 regulator of chromosome condensation, RCC1 - - - 0.000000000008605 76.0
HFD1_k127_3696991_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000003993 172.0
HFD1_k127_3696991_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01907 - 6.2.1.16 0.000000000000000000000000000001751 122.0
HFD1_k127_3696991_2 PAS domain - - - 0.000000000000000000000000003145 122.0
HFD1_k127_3696991_3 Histidine kinase - - - 0.00000000000485 68.0
HFD1_k127_3696991_4 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000005294 68.0
HFD1_k127_3697674_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 3.706e-226 709.0
HFD1_k127_3697674_1 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 532.0
HFD1_k127_3697674_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 476.0
HFD1_k127_3697674_3 COG1233 Phytoene dehydrogenase and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 462.0
HFD1_k127_3697674_4 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 438.0
HFD1_k127_3697674_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 396.0
HFD1_k127_3697674_6 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000002488 211.0
HFD1_k127_3697674_7 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000185 186.0
HFD1_k127_3697674_8 4 iron, 4 sulfur cluster binding K03522,K13795,K15511,K19516 - 1.14.13.208 0.0000000000000000000000000000003932 126.0
HFD1_k127_3697674_9 Flavin containing amine oxidoreductase - - - 0.00000009561 53.0
HFD1_k127_3708092_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 474.0
HFD1_k127_3708092_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 385.0
HFD1_k127_3708092_2 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 362.0
HFD1_k127_3708092_3 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 359.0
HFD1_k127_3708092_4 peptidyl-tyrosine sulfation K03217,K06872 - - 0.000000000000000000000000000000000000000000000000000000000001456 222.0
HFD1_k127_3708092_5 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000004576 154.0
HFD1_k127_3708092_6 Membrane - - - 0.0000000000000000000000000000000000001192 151.0
HFD1_k127_3708092_7 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000005004 100.0
HFD1_k127_3729118_0 AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 502.0
HFD1_k127_3729118_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 466.0
HFD1_k127_3729118_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 383.0
HFD1_k127_3729118_3 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 360.0
HFD1_k127_3729118_4 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 340.0
HFD1_k127_3729118_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000004458 212.0
HFD1_k127_3729118_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000007812 193.0
HFD1_k127_3729118_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000003639 120.0
HFD1_k127_3732691_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 9.826e-229 717.0
HFD1_k127_3732691_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 314.0
HFD1_k127_3732691_2 TIGRFAM MazG family protein K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000008559 148.0
HFD1_k127_3736363_0 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 500.0
HFD1_k127_3736363_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 494.0
HFD1_k127_3736363_2 Indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000008865 224.0
HFD1_k127_3736363_3 ECF sigma factor K03088 - - 0.0000000000000000000000101 104.0
HFD1_k127_3744027_0 Conserved carboxylase domain K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 506.0
HFD1_k127_3744027_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 432.0
HFD1_k127_3744027_2 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 389.0
HFD1_k127_3744027_3 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 292.0
HFD1_k127_3744027_4 Fumarate K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002753 267.0
HFD1_k127_3744027_5 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005077 254.0
HFD1_k127_3744027_6 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000002323 237.0
HFD1_k127_3744027_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000633 144.0
HFD1_k127_375485_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 481.0
HFD1_k127_375485_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004808 295.0
HFD1_k127_375485_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000004906 180.0
HFD1_k127_375485_3 TIGRFAM PAS domain S-box K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000001896 191.0
HFD1_k127_375485_4 - - - - 0.0002049 52.0
HFD1_k127_3760679_0 Psort location CytoplasmicMembrane, score K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 402.0
HFD1_k127_3760679_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 376.0
HFD1_k127_3760679_10 - - - - 0.000000000000000000000000000000000004152 145.0
HFD1_k127_3760679_11 - - - - 0.000000000000000000000000000003351 127.0
HFD1_k127_3760679_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000005245 71.0
HFD1_k127_3760679_13 Domain of unknown function (DUF4115) - - - 0.00000000006575 68.0
HFD1_k127_3760679_2 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 323.0
HFD1_k127_3760679_3 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007287 277.0
HFD1_k127_3760679_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009892 265.0
HFD1_k127_3760679_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001431 244.0
HFD1_k127_3760679_6 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004909 225.0
HFD1_k127_3760679_7 2-keto-3-deoxy-L-rhamnonate aldolase activity K01630,K02510 - 4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000000001806 197.0
HFD1_k127_3760679_8 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000191 189.0
HFD1_k127_3760679_9 HPP family - - - 0.0000000000000000000000000000000000000000000000008876 179.0
HFD1_k127_3823_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001289 277.0
HFD1_k127_3823_1 Flavodoxin domain K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000001467 241.0
HFD1_k127_3823_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000004729 163.0
HFD1_k127_3827052_0 branched-chain amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004937 290.0
HFD1_k127_3827052_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004845 245.0
HFD1_k127_3827052_2 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000003844 236.0
HFD1_k127_3827052_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000002702 171.0
HFD1_k127_383966_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 507.0
HFD1_k127_383966_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 424.0
HFD1_k127_383966_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 290.0
HFD1_k127_383966_3 COG1233 Phytoene dehydrogenase and related - - - 0.000000000000000000000000000000000000000000000000000003218 206.0
HFD1_k127_385523_0 Sigma-54 interaction domain K07714,K07715 - - 4.973e-214 673.0
HFD1_k127_385523_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 520.0
HFD1_k127_385523_2 nuclear chromosome segregation - - - 0.000000000000000000000000000005742 128.0
HFD1_k127_385523_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000008392 115.0
HFD1_k127_385523_4 cheY-homologous receiver domain - - - 0.0000000000000004998 82.0
HFD1_k127_3869040_0 - - - - 0.000000000000000000000000000000000000000003389 159.0
HFD1_k127_3869040_1 translation initiation factor activity K03699 - - 0.000000000000000000000000000000000153 143.0
HFD1_k127_3869040_2 PFAM aldo keto reductase - - - 0.0000000000000000000000005109 105.0
HFD1_k127_389827_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 5.745e-234 741.0
HFD1_k127_389827_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000001062 262.0
HFD1_k127_389827_10 cheY-homologous receiver domain - - - 0.000000152 55.0
HFD1_k127_389827_11 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.000004197 58.0
HFD1_k127_389827_2 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000003004 261.0
HFD1_k127_389827_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001958 239.0
HFD1_k127_389827_4 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000002372 199.0
HFD1_k127_389827_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000006691 188.0
HFD1_k127_389827_6 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000001696 127.0
HFD1_k127_389827_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000003169 75.0
HFD1_k127_389827_8 Belongs to the IPP transferase family K00791 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000002946 59.0
HFD1_k127_389827_9 gas vesicle protein - - - 0.00000005296 59.0
HFD1_k127_390407_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 422.0
HFD1_k127_390407_1 DeoC/LacD family aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 303.0
HFD1_k127_390407_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000003565 235.0
HFD1_k127_390407_3 PFAM periplasmic binding protein LacI transcriptional regulator K10439 - - 0.00000000000000000000000000005819 129.0
HFD1_k127_3929968_0 Histidine kinase K19693 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 299.0
HFD1_k127_3929968_1 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003298 301.0
HFD1_k127_3929968_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000651 228.0
HFD1_k127_3929968_3 Histidine kinase - - - 0.0000000000000000000000000000000009748 151.0
HFD1_k127_3929968_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000004157 134.0
HFD1_k127_3929968_5 - K19687 - - 0.00000000000001464 76.0
HFD1_k127_3950318_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 594.0
HFD1_k127_3950318_1 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000104 190.0
HFD1_k127_3950318_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000008697 164.0
HFD1_k127_3950318_3 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000316 108.0
HFD1_k127_3950318_4 - - - - 0.0000004291 56.0
HFD1_k127_395948_0 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 313.0
HFD1_k127_395948_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000001475 189.0
HFD1_k127_395948_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0005322 49.0
HFD1_k127_396608_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 9.546e-287 899.0
HFD1_k127_396608_1 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000008986 202.0
HFD1_k127_396608_2 2Fe-2S -binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000001969 195.0
HFD1_k127_396608_3 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000004667 81.0
HFD1_k127_39833_0 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 470.0
HFD1_k127_39833_1 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 301.0
HFD1_k127_39833_2 enoyl-CoA hydratase isomerase K01715 - 4.2.1.17 0.0000000000000117 75.0
HFD1_k127_39833_3 Protein of unknown function (DUF3426) - - - 0.00000002517 64.0
HFD1_k127_399980_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 555.0
HFD1_k127_399980_1 gluconate transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 306.0
HFD1_k127_399980_2 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003076 255.0
HFD1_k127_399980_3 Putative RNA methylase family UPF0020 - - - 0.00000000000000000000000000000000000000000000000000002668 207.0
HFD1_k127_399980_4 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000002932 148.0
HFD1_k127_4001633_0 FecR protein - - - 0.0 1180.0
HFD1_k127_4001633_1 CHASE2 K01768 - 4.6.1.1 5.224e-250 792.0
HFD1_k127_4001633_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 336.0
HFD1_k127_4001633_3 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001388 282.0
HFD1_k127_4001633_4 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000003394 126.0
HFD1_k127_4001633_5 phosphorelay signal transduction system - - - 0.00000000000000000000000003343 111.0
HFD1_k127_4024346_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 544.0
HFD1_k127_4024346_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000001722 259.0
HFD1_k127_4024346_2 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000001547 162.0
HFD1_k127_4024346_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000002883 139.0
HFD1_k127_4024346_4 methyltransferase - - - 0.000000000000000000000003739 111.0
HFD1_k127_4029864_0 PFAM Formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 349.0
HFD1_k127_4029864_1 - - - - 0.00000000000000000000000000000000000000000000000006156 189.0
HFD1_k127_4029864_2 Methenyl tetrahydrofolate cyclohydrolase - - - 0.0000000000000000000000000003745 121.0
HFD1_k127_4029864_3 - - - - 0.000000000000000000000000002482 114.0
HFD1_k127_4029864_4 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000008788 112.0
HFD1_k127_4053241_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 2.292e-210 679.0
HFD1_k127_4053241_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 610.0
HFD1_k127_4053241_10 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000001429 137.0
HFD1_k127_4053241_11 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000001068 132.0
HFD1_k127_4053241_12 Cytochrome c K00413 - - 0.00000000000000000000000000000666 125.0
HFD1_k127_4053241_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 497.0
HFD1_k127_4053241_3 Fe-S center protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 441.0
HFD1_k127_4053241_4 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 414.0
HFD1_k127_4053241_5 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 337.0
HFD1_k127_4053241_6 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 314.0
HFD1_k127_4053241_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000262 242.0
HFD1_k127_4053241_8 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000000000000000000000000009811 194.0
HFD1_k127_4053241_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000002431 190.0
HFD1_k127_4054792_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 481.0
HFD1_k127_4054792_1 D-galactarate dehydratase / Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 384.0
HFD1_k127_4054792_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 339.0
HFD1_k127_4054792_3 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 319.0
HFD1_k127_4054792_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
HFD1_k127_4054792_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000005288 232.0
HFD1_k127_4054792_6 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000001631 197.0
HFD1_k127_4054792_7 - - - - 0.0000000000000000008305 100.0
HFD1_k127_4054792_8 PFAM SAF domain K16849 - 4.2.1.7 0.0000000000000001982 81.0
HFD1_k127_4054792_9 DNA excision - - - 0.00001053 49.0
HFD1_k127_40940_0 PFAM Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 5.422e-251 787.0
HFD1_k127_40940_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 387.0
HFD1_k127_40940_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 301.0
HFD1_k127_40940_3 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 306.0
HFD1_k127_40940_4 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000002307 225.0
HFD1_k127_40940_5 - - - - 0.0000000000000000000000000000000001876 134.0
HFD1_k127_4101774_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 521.0
HFD1_k127_4101774_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 504.0
HFD1_k127_4101774_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000002098 236.0
HFD1_k127_4101774_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000002383 173.0
HFD1_k127_4101774_4 sulfurtransferase K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000002665 175.0
HFD1_k127_4113568_0 Aromatic ring hydroxylase K14534 - 4.2.1.120,5.3.3.3 4.305e-219 689.0
HFD1_k127_4113568_1 PFAM regulatory protein MerR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003231 258.0
HFD1_k127_4113568_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000001888 184.0
HFD1_k127_4113568_3 Belongs to the enoyl-CoA hydratase isomerase family K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000002373 166.0
HFD1_k127_4142080_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 357.0
HFD1_k127_4142080_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 321.0
HFD1_k127_4142080_2 alpha/beta hydrolase fold K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 316.0
HFD1_k127_4142080_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 304.0
HFD1_k127_4142080_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001016 282.0
HFD1_k127_4160360_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 588.0
HFD1_k127_4160360_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 496.0
HFD1_k127_4160360_10 Methylene-tetrahydrofolate reductase C terminal - - - 0.000001612 51.0
HFD1_k127_4160360_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001787 261.0
HFD1_k127_4160360_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007252 256.0
HFD1_k127_4160360_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000002306 229.0
HFD1_k127_4160360_5 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000002527 181.0
HFD1_k127_4160360_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000001318 154.0
HFD1_k127_4160360_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000003839 160.0
HFD1_k127_4160360_8 Class III cytochrome C family - - - 0.000000000000000000001548 100.0
HFD1_k127_4160360_9 - - - - 0.00000007498 60.0
HFD1_k127_4166428_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 533.0
HFD1_k127_4166428_1 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 336.0
HFD1_k127_4166428_2 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004102 283.0
HFD1_k127_4166428_3 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000000000000000000000000000000000000007231 171.0
HFD1_k127_4172019_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 571.0
HFD1_k127_4172019_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 443.0
HFD1_k127_4172019_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 375.0
HFD1_k127_4172019_3 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 361.0
HFD1_k127_4172019_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 343.0
HFD1_k127_4172019_5 Psort location Cytoplasmic, score 8.87 K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 310.0
HFD1_k127_4172019_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 294.0
HFD1_k127_4172019_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000006475 166.0
HFD1_k127_4172019_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000001141 151.0
HFD1_k127_4172019_9 - - - - 0.000000000003282 73.0
HFD1_k127_4172215_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 483.0
HFD1_k127_4172215_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001714 263.0
HFD1_k127_4172215_2 ATPase (AAA K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000319 242.0
HFD1_k127_4172215_3 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002143 205.0
HFD1_k127_4172215_4 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000005048 110.0
HFD1_k127_4172215_5 Protein of unknown function (DUF3309) - - - 0.00000000000005343 72.0
HFD1_k127_4180382_0 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 341.0
HFD1_k127_4180382_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000013 280.0
HFD1_k127_4180382_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087,K20447 - 1.17.1.4,1.17.1.5 0.00000000000000000000000000000000000000000000000000000003233 201.0
HFD1_k127_4180382_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000629 197.0
HFD1_k127_4180382_4 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.0000000000001346 75.0
HFD1_k127_4186187_0 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 517.0
HFD1_k127_4186187_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 287.0
HFD1_k127_4186187_2 3-hydroxyacyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001393 255.0
HFD1_k127_4186187_3 radical SAM domain protein - - - 0.0000005188 54.0
HFD1_k127_4186187_4 Acetyltransferase (GNAT) domain - - - 0.0001619 49.0
HFD1_k127_4201718_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1070.0
HFD1_k127_4201718_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 510.0
HFD1_k127_4201718_10 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000002093 102.0
HFD1_k127_4201718_11 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001126 71.0
HFD1_k127_4201718_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000006735 67.0
HFD1_k127_4201718_2 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 459.0
HFD1_k127_4201718_3 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 439.0
HFD1_k127_4201718_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 437.0
HFD1_k127_4201718_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 374.0
HFD1_k127_4201718_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 327.0
HFD1_k127_4201718_7 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 317.0
HFD1_k127_4201718_8 Beta-lactamase superfamily domain K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001159 268.0
HFD1_k127_4201718_9 Jag_N K06346 - - 0.00000000000000000000000000001063 123.0
HFD1_k127_4221423_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 302.0
HFD1_k127_4221423_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 295.0
HFD1_k127_4221423_2 DNA photolyase activity K03716 - 4.1.99.14 0.0000000000000000000000000000000000000000000000000000000000000004753 227.0
HFD1_k127_4221423_3 ParB-like nuclease domain K03497 - - 0.000000000000000000000000136 119.0
HFD1_k127_4221423_4 - - - - 0.0000000000000000003047 92.0
HFD1_k127_4232018_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 356.0
HFD1_k127_4232018_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 331.0
HFD1_k127_4232018_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000009234 163.0
HFD1_k127_4232018_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000007627 123.0
HFD1_k127_4235680_0 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 596.0
HFD1_k127_4235680_1 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 475.0
HFD1_k127_4235680_10 Cytosol aminopeptidase family, N-terminal domain - - - 0.000000007979 64.0
HFD1_k127_4235680_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 404.0
HFD1_k127_4235680_3 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001779 252.0
HFD1_k127_4235680_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000002796 244.0
HFD1_k127_4235680_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000006803 241.0
HFD1_k127_4235680_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000007202 216.0
HFD1_k127_4235680_7 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000007058 209.0
HFD1_k127_4235680_8 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000002162 166.0
HFD1_k127_4235680_9 NusB family K03625 - - 0.0000000000000000000000000000000006199 135.0
HFD1_k127_4268861_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 7.757e-202 635.0
HFD1_k127_4268861_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 430.0
HFD1_k127_4268861_2 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000000002502 207.0
HFD1_k127_4268861_3 MlaD protein K02067 - - 0.0000000000000000000001597 102.0
HFD1_k127_4268861_4 Peptidase family M48 - - - 0.0000005956 57.0
HFD1_k127_4274709_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000007806 252.0
HFD1_k127_4274709_1 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000009069 239.0
HFD1_k127_4274709_2 PFAM Transketolase K21417 - - 0.00000000000000000000000000000000000000000000000000000000003612 208.0
HFD1_k127_4274709_3 PFAM short-chain dehydrogenase reductase SDR K00059,K00068,K03366 - 1.1.1.100,1.1.1.140,1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000005731 199.0
HFD1_k127_4274709_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000005663 174.0
HFD1_k127_4274709_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000008437 90.0
HFD1_k127_4279562_0 fatty acid transporter K02106 - - 1.664e-198 629.0
HFD1_k127_4279562_1 - - - - 0.00000000000000000000000000000000000000000000000000000004335 206.0
HFD1_k127_4332543_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 349.0
HFD1_k127_4332543_1 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006414 252.0
HFD1_k127_4332543_2 Branched-chain amino acid transport system, permease component K01997,K01998,K11955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001264 256.0
HFD1_k127_4332543_3 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001007 247.0
HFD1_k127_4332543_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000218 220.0
HFD1_k127_4332543_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000006121 214.0
HFD1_k127_4332543_6 - - - - 0.0000000008608 67.0
HFD1_k127_4333534_0 Belongs to the enoyl-CoA hydratase isomerase family K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 515.0
HFD1_k127_4333534_1 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 502.0
HFD1_k127_433579_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 403.0
HFD1_k127_433579_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 285.0
HFD1_k127_433579_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000001424 196.0
HFD1_k127_433579_3 sequence-specific DNA binding K18830 - - 0.00000000000000000000000000000000000000000003758 164.0
HFD1_k127_433579_4 Predicted membrane protein (DUF2318) K09005 - - 0.00000000000000000000000000000000000000299 155.0
HFD1_k127_433579_5 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000002172 143.0
HFD1_k127_433579_6 membrane - - - 0.000000000000000000000000000004371 126.0
HFD1_k127_433579_7 peptidyl-prolyl cis-trans isomerase activity K03770,K07533 - 5.2.1.8 0.000001106 60.0
HFD1_k127_4347307_0 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 377.0
HFD1_k127_4347307_1 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001215 276.0
HFD1_k127_4347307_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000003298 231.0
HFD1_k127_4347307_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000002259 98.0
HFD1_k127_4347307_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000003586 66.0
HFD1_k127_4347307_5 Lytic murein transglycosylase K08309 - - 0.00001864 51.0
HFD1_k127_4348060_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1863.0
HFD1_k127_4348060_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 337.0
HFD1_k127_4348060_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 323.0
HFD1_k127_4348060_3 Ribosomal protein L11/L12 K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001271 223.0
HFD1_k127_4348060_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000001591 162.0
HFD1_k127_4348060_5 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.000000000000000000000000000000000000000000301 159.0
HFD1_k127_4348060_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000002295 153.0
HFD1_k127_4353114_0 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 454.0
HFD1_k127_4353114_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 357.0
HFD1_k127_4353114_2 ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 350.0
HFD1_k127_4353114_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 304.0
HFD1_k127_4359592_0 PFAM Carboxyl transferase domain - - - 1.116e-250 781.0
HFD1_k127_4359592_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 462.0
HFD1_k127_4359592_2 PFAM short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 318.0
HFD1_k127_4359592_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
HFD1_k127_4359592_4 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002738 258.0
HFD1_k127_4369566_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000001594 223.0
HFD1_k127_4369566_1 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000005242 220.0
HFD1_k127_4369566_2 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000006392 201.0
HFD1_k127_4378169_0 4-alpha-glucanotransferase K00700,K00705,K02438,K06044 - 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 1.503e-211 675.0
HFD1_k127_4378169_1 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 595.0
HFD1_k127_4378169_2 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000008349 151.0
HFD1_k127_4378169_3 Belongs to the ompA family - - - 0.0000000000000000000000000000000000003864 148.0
HFD1_k127_4378169_4 FecR protein - - - 0.00000000000000000000000000000000001406 142.0
HFD1_k127_4378169_5 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0000009963 51.0
HFD1_k127_4396327_0 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 292.0
HFD1_k127_4396327_1 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000005606 177.0
HFD1_k127_4396327_2 Putative peptidoglycan binding domain K21470 - - 0.00000000000000000000000000000001447 134.0
HFD1_k127_4396327_3 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000005372 82.0
HFD1_k127_4439636_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 325.0
HFD1_k127_4461267_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 3.542e-297 924.0
HFD1_k127_4461267_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 372.0
HFD1_k127_4461267_2 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 355.0
HFD1_k127_4461267_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000003046 241.0
HFD1_k127_4461267_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000002065 228.0
HFD1_k127_4461267_5 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000000000000000002058 191.0
HFD1_k127_4461267_6 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000002137 183.0
HFD1_k127_4461267_7 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000001378 154.0
HFD1_k127_4461267_8 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000002467 103.0
HFD1_k127_4488174_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 4.048e-195 615.0
HFD1_k127_4488174_1 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007079 261.0
HFD1_k127_4488174_2 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000009626 242.0
HFD1_k127_4488174_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000004579 181.0
HFD1_k127_4488174_4 Branched-chain amino acid ABC transporter substrate-binding protein K01999 - - 0.00000000000000000000000000000004725 133.0
HFD1_k127_4488174_5 PFAM thioesterase superfamily K02614 - - 0.00000000000000000001357 96.0
HFD1_k127_4488174_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.00001077 47.0
HFD1_k127_4491268_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 465.0
HFD1_k127_4491268_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 464.0
HFD1_k127_4491268_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 364.0
HFD1_k127_4491268_3 L-phenylalanine transmembrane transporter activity K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 326.0
HFD1_k127_4491268_4 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 297.0
HFD1_k127_4491268_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006459 280.0
HFD1_k127_4491268_6 Histidine kinase - - - 0.00000000000000000000000000004958 137.0
HFD1_k127_4507434_0 ABC transporter substrate-binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 387.0
HFD1_k127_4507434_1 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 341.0
HFD1_k127_4507434_10 metal-dependent hydrolase of the TIM-barrel fold K07045,K22213 - 4.1.1.52 0.00000000000000000000000000005162 126.0
HFD1_k127_4507434_2 Psort location CytoplasmicMembrane, score 10.00 K01998,K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000507 280.0
HFD1_k127_4507434_3 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001271 266.0
HFD1_k127_4507434_4 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000782 256.0
HFD1_k127_4507434_5 Psort location CytoplasmicMembrane, score 10.00 K01997,K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002063 254.0
HFD1_k127_4507434_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000001208 248.0
HFD1_k127_4507434_7 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002159 246.0
HFD1_k127_4507434_8 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000004031 245.0
HFD1_k127_4507434_9 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000001239 128.0
HFD1_k127_4511743_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 2.133e-218 687.0
HFD1_k127_4511743_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 362.0
HFD1_k127_4511743_2 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000371 283.0
HFD1_k127_4511743_3 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007474 256.0
HFD1_k127_4511743_4 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000004649 171.0
HFD1_k127_4523475_0 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002565 260.0
HFD1_k127_4523475_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000001362 149.0
HFD1_k127_4523475_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000002082 66.0
HFD1_k127_4538154_0 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 458.0
HFD1_k127_4538154_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 333.0
HFD1_k127_4538154_2 YdjC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 246.0
HFD1_k127_4538154_4 Belongs to the FPG family K05522 - 4.2.99.18 0.00000000000000000000000000000000000004842 152.0
HFD1_k127_4538154_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000297 128.0
HFD1_k127_4538154_6 NADPH-dependent FMN reductase - - - 0.0000001722 53.0
HFD1_k127_4567537_0 Ftsk_gamma K03466 - - 1.601e-219 703.0
HFD1_k127_4567537_1 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 500.0
HFD1_k127_4567537_10 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000004771 143.0
HFD1_k127_4567537_11 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000001849 90.0
HFD1_k127_4567537_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 402.0
HFD1_k127_4567537_3 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 372.0
HFD1_k127_4567537_4 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 362.0
HFD1_k127_4567537_5 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 312.0
HFD1_k127_4567537_6 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000004486 211.0
HFD1_k127_4567537_7 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000004605 198.0
HFD1_k127_4567537_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000004966 172.0
HFD1_k127_4567537_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000004913 176.0
HFD1_k127_4569235_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 4.989e-249 793.0
HFD1_k127_4569235_1 PFAM PrkA AAA domain K07180 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 599.0
HFD1_k127_4569235_10 SpoVR like protein K06415 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000000000000000000000006053 113.0
HFD1_k127_4569235_11 - - - - 0.000000000000000000000000009901 121.0
HFD1_k127_4569235_12 - - - - 0.00000000000000000001614 94.0
HFD1_k127_4569235_13 Cation transport regulator K06197 - - 0.000000001697 61.0
HFD1_k127_4569235_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 485.0
HFD1_k127_4569235_3 Mur ligase middle domain K01932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 400.0
HFD1_k127_4569235_4 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 351.0
HFD1_k127_4569235_5 Ku70/Ku80 beta-barrel domain K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 318.0
HFD1_k127_4569235_6 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003797 289.0
HFD1_k127_4569235_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003743 242.0
HFD1_k127_4569235_8 PFAM response regulator receiver - - - 0.0000000000000000000000000000002461 128.0
HFD1_k127_4569235_9 Capsule biosynthesis CapC K22116 - - 0.000000000000000000000000000001773 126.0
HFD1_k127_4569830_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001225 281.0
HFD1_k127_4569830_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000003156 269.0
HFD1_k127_4569830_2 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002163 262.0
HFD1_k127_4569830_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000001899 240.0
HFD1_k127_4569830_4 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000005085 239.0
HFD1_k127_4569830_5 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000001781 116.0
HFD1_k127_4569830_6 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000003162 95.0
HFD1_k127_4594522_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1221.0
HFD1_k127_4594522_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 4.785e-219 690.0
HFD1_k127_4594522_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 357.0
HFD1_k127_4594522_3 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000002033 188.0
HFD1_k127_4594522_4 peptidyl-tyrosine sulfation - - - 0.000543 50.0
HFD1_k127_4597737_0 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 494.0
HFD1_k127_4597737_1 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000007684 243.0
HFD1_k127_4597737_3 Methyltransferase type - - - 0.00000000000007372 71.0
HFD1_k127_462237_0 PFAM MltA K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 323.0
HFD1_k127_462237_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 311.0
HFD1_k127_462237_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000001778 112.0
HFD1_k127_4624318_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 468.0
HFD1_k127_4624318_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 359.0
HFD1_k127_4624318_2 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 264.0
HFD1_k127_4624318_3 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000144 144.0
HFD1_k127_4627371_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 529.0
HFD1_k127_4627371_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 416.0
HFD1_k127_4627371_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 293.0
HFD1_k127_4627371_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000008264 230.0
HFD1_k127_4627371_4 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000001247 160.0
HFD1_k127_4656541_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 576.0
HFD1_k127_4656541_1 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001001 263.0
HFD1_k127_4656541_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001031 242.0
HFD1_k127_4673235_0 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003106 283.0
HFD1_k127_4673235_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000001058 231.0
HFD1_k127_4673235_2 molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000000000000000003651 218.0
HFD1_k127_4673235_3 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000002184 208.0
HFD1_k127_4673235_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.0000000000000000000000000000000000000000000000000002936 191.0
HFD1_k127_4681038_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 355.0
HFD1_k127_4681038_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 306.0
HFD1_k127_4681038_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000008999 241.0
HFD1_k127_4690574_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 470.0
HFD1_k127_4690574_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000001476 178.0
HFD1_k127_4691848_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000002364 70.0
HFD1_k127_4691848_1 - - - - 0.0000000000005859 82.0
HFD1_k127_4691848_2 - - - - 0.0001412 49.0
HFD1_k127_4700711_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 377.0
HFD1_k127_4700711_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002615 263.0
HFD1_k127_4700711_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002696 255.0
HFD1_k127_4700711_3 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000001941 223.0
HFD1_k127_4700711_4 Phosphoadenosine phosphosulfate reductase family K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000006185 147.0
HFD1_k127_4700711_5 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000000000000000000006439 111.0
HFD1_k127_4700711_6 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000005775 81.0
HFD1_k127_4715967_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 628.0
HFD1_k127_4715967_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 367.0
HFD1_k127_4715967_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 317.0
HFD1_k127_4715967_3 - - - - 0.000000000000000000000000007283 113.0
HFD1_k127_4715967_4 Competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.000000009632 63.0
HFD1_k127_4719376_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 4.865e-277 860.0
HFD1_k127_4719376_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 378.0
HFD1_k127_4719376_2 Protein of unknown function DUF89 K09680 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000001927 251.0
HFD1_k127_472939_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.311e-296 920.0
HFD1_k127_472939_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 416.0
HFD1_k127_472939_2 4Fe-4S binding domain K02572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 367.0
HFD1_k127_472939_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002418 249.0
HFD1_k127_4733866_0 Elongation factor Tu domain 2 K02355 - - 1.1e-237 750.0
HFD1_k127_4733866_1 Amino acid polyamine organocation transporter, APC superfamily K03294 - - 5.55e-235 737.0
HFD1_k127_4733866_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 478.0
HFD1_k127_4733866_3 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000001286 207.0
HFD1_k127_4733866_4 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000005538 198.0
HFD1_k127_4733866_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000003836 184.0
HFD1_k127_4733866_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000004381 121.0
HFD1_k127_4733866_7 TrkA-N domain K03499,K10716 - - 0.0000000000000000000000000007735 117.0
HFD1_k127_4744375_0 Tim44 K02117,K08678,K11646,K15539,K17835,K21636 - 1.1.98.6,1.4.1.24,3.6.3.14,3.6.3.15,4.1.1.35,4.1.99.20 2.299e-226 736.0
HFD1_k127_4744375_1 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 407.0
HFD1_k127_4744375_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 381.0
HFD1_k127_4744375_3 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 373.0
HFD1_k127_4744375_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000008929 213.0
HFD1_k127_4744375_5 CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000001414 156.0
HFD1_k127_4744375_6 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000007711 113.0
HFD1_k127_4744375_7 Universal stress protein - - - 0.0000000000000000000002483 110.0
HFD1_k127_4744375_9 - - - - 0.000006375 54.0
HFD1_k127_4805097_0 Glucose / Sorbosone dehydrogenase - - - 1.895e-211 664.0
HFD1_k127_4805097_1 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 508.0
HFD1_k127_4805097_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 460.0
HFD1_k127_4805097_3 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 424.0
HFD1_k127_4805097_4 Receptor family ligand binding region family protein 22 K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 335.0
HFD1_k127_4805097_5 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 302.0
HFD1_k127_4805097_6 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 270.0
HFD1_k127_4805097_7 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006118 267.0
HFD1_k127_4805097_8 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001416 274.0
HFD1_k127_4805097_9 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008612 225.0
HFD1_k127_4811785_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 522.0
HFD1_k127_4811785_1 4Fe-4S binding domain - - - 0.0000000000000000004721 87.0
HFD1_k127_4815943_0 Elongator protein 3, MiaB family, Radical SAM - - - 8.364e-196 617.0
HFD1_k127_4815943_1 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 2.513e-195 633.0
HFD1_k127_4815943_10 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.000000005299 62.0
HFD1_k127_4815943_11 dehydratase - - - 0.000000384 58.0
HFD1_k127_4815943_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 428.0
HFD1_k127_4815943_3 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 298.0
HFD1_k127_4815943_4 lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000002136 188.0
HFD1_k127_4815943_5 3-oxoacyl-ACP synthase - - - 0.00000000000000000000000000000000000000000000001594 178.0
HFD1_k127_4815943_6 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000008274 114.0
HFD1_k127_4815943_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000007777 116.0
HFD1_k127_4815943_8 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000004924 109.0
HFD1_k127_4815943_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000009722 66.0
HFD1_k127_4817781_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 481.0
HFD1_k127_4846332_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.515e-226 712.0
HFD1_k127_4846332_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.816e-202 638.0
HFD1_k127_4846332_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000001216 149.0
HFD1_k127_4846332_11 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000003048 106.0
HFD1_k127_4846332_12 TIGRFAM competence protein ComEA helix-hairpin-helix repeat region K02237 - - 0.000000000000581 78.0
HFD1_k127_4846332_2 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 561.0
HFD1_k127_4846332_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 492.0
HFD1_k127_4846332_4 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 366.0
HFD1_k127_4846332_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 326.0
HFD1_k127_4846332_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 296.0
HFD1_k127_4846332_7 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008313 280.0
HFD1_k127_4846332_8 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000001044 179.0
HFD1_k127_4846332_9 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000002762 173.0
HFD1_k127_4870811_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 506.0
HFD1_k127_4870811_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 408.0
HFD1_k127_4870811_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000001083 245.0
HFD1_k127_4870811_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000002327 150.0
HFD1_k127_4870811_4 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.0000000000002741 76.0
HFD1_k127_4876310_0 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009092 252.0
HFD1_k127_4876310_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000002739 240.0
HFD1_k127_4876310_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000001568 212.0
HFD1_k127_4876310_3 Belongs to the binding-protein-dependent transport system permease family K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000005877 80.0
HFD1_k127_4880868_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1372.0
HFD1_k127_4880868_1 PilZ domain K03406 - - 0.00005823 51.0
HFD1_k127_4883255_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.611e-279 876.0
HFD1_k127_4883255_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 509.0
HFD1_k127_4883255_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 449.0
HFD1_k127_4883255_3 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 345.0
HFD1_k127_4883255_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 311.0
HFD1_k127_4883255_5 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001043 280.0
HFD1_k127_4883255_6 - - - - 0.0000000000000000000000000000000000000002733 157.0
HFD1_k127_4883255_7 Lysin motif - - - 0.000000000000000000001968 102.0
HFD1_k127_4884016_0 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 313.0
HFD1_k127_4884016_1 PIN domain - - - 0.000000000001109 71.0
HFD1_k127_4909925_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 471.0
HFD1_k127_4909925_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 310.0
HFD1_k127_4909925_2 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000003636 226.0
HFD1_k127_4909925_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000003576 158.0
HFD1_k127_4909925_4 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000006289 149.0
HFD1_k127_4909925_5 Phage integrase family - - - 0.0002688 44.0
HFD1_k127_4911985_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 388.0
HFD1_k127_4911985_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 331.0
HFD1_k127_4911985_2 oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000001457 129.0
HFD1_k127_4911985_3 Membrane - - - 0.00000000000000002073 93.0
HFD1_k127_4911985_4 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000002153 81.0
HFD1_k127_4911985_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000001261 79.0
HFD1_k127_4946478_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 294.0
HFD1_k127_4946478_1 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004087 249.0
HFD1_k127_4946478_2 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000641 151.0
HFD1_k127_495070_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 3.263e-230 720.0
HFD1_k127_495070_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 539.0
HFD1_k127_495070_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 494.0
HFD1_k127_495070_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 308.0
HFD1_k127_495070_4 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 287.0
HFD1_k127_495070_5 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000001227 182.0
HFD1_k127_495070_6 Calcineurin-like phosphoesterase K01081,K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000001662 115.0
HFD1_k127_4962612_0 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 514.0
HFD1_k127_4962612_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 356.0
HFD1_k127_4962612_2 Domain of unknown function (DUF4203) - - - 0.000000000000000000000000000000007234 134.0
HFD1_k127_4962612_3 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000509 100.0
HFD1_k127_4962612_4 Major facilitator Superfamily - - - 0.00000000000000003398 88.0
HFD1_k127_4962612_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000142 75.0
HFD1_k127_4962612_6 PFAM ATP-grasp domain - - - 0.0000005352 53.0
HFD1_k127_4986641_0 PFAM Tannase and feruloyl esterase K21105 - 3.1.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 606.0
HFD1_k127_4986641_1 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000691 240.0
HFD1_k127_4989114_0 Bacterial protein of unknown function (DUF853) K06915 - - 8.543e-228 713.0
HFD1_k127_4989114_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 545.0
HFD1_k127_4989114_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 324.0
HFD1_k127_4989114_3 Protein of unknown function (DUF4197) - - - 0.000000000000009809 74.0
HFD1_k127_5000470_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 5.465e-239 758.0
HFD1_k127_5000470_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 9.111e-215 674.0
HFD1_k127_5000470_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 359.0
HFD1_k127_5000470_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 288.0
HFD1_k127_5000470_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000294 248.0
HFD1_k127_5000470_13 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000002708 249.0
HFD1_k127_5000470_14 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000427 245.0
HFD1_k127_5000470_15 Psort location CytoplasmicMembrane, score K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000002297 236.0
HFD1_k127_5000470_16 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000004479 237.0
HFD1_k127_5000470_17 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000005863 206.0
HFD1_k127_5000470_18 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000004338 173.0
HFD1_k127_5000470_19 - - - - 0.0000000000000000000000000000000195 131.0
HFD1_k127_5000470_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 610.0
HFD1_k127_5000470_21 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000005426 70.0
HFD1_k127_5000470_22 Cell division protein FtsL - - - 0.0000000002006 66.0
HFD1_k127_5000470_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 599.0
HFD1_k127_5000470_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 519.0
HFD1_k127_5000470_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 505.0
HFD1_k127_5000470_6 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 482.0
HFD1_k127_5000470_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 468.0
HFD1_k127_5000470_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 381.0
HFD1_k127_5000470_9 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 374.0
HFD1_k127_5012263_0 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 422.0
HFD1_k127_5012263_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 336.0
HFD1_k127_5012263_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 296.0
HFD1_k127_5012263_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004108 263.0
HFD1_k127_5012263_4 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002481 254.0
HFD1_k127_5012263_5 NTPase - - - 0.00000000000000000000000000000000000000000000009995 174.0
HFD1_k127_5012263_6 - K01507 - 3.6.1.1 0.00000000000000000000000000002159 120.0
HFD1_k127_5034088_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 372.0
HFD1_k127_5034088_1 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000007118 146.0
HFD1_k127_5034088_2 - - - - 0.000000000000001634 89.0
HFD1_k127_5037800_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 445.0
HFD1_k127_5037800_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 402.0
HFD1_k127_5037800_2 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 343.0
HFD1_k127_5037800_3 Vi polysaccharide biosynthesis protein VipB TviC K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000002345 85.0
HFD1_k127_5037800_4 Diadenylate cyclase - - - 0.0000000000002038 76.0
HFD1_k127_5037800_5 Tetratricopeptide repeat - - - 0.00000005882 61.0
HFD1_k127_5048185_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.581e-251 801.0
HFD1_k127_5048185_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 484.0
HFD1_k127_5048185_2 tRNA pseudouridylate synthase B C-terminal domain K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000217 252.0
HFD1_k127_5048185_3 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000004699 167.0
HFD1_k127_5048185_4 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000002967 154.0
HFD1_k127_5048185_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000001082 128.0
HFD1_k127_5048185_6 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000008473 103.0
HFD1_k127_5048185_7 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.000000003354 63.0
HFD1_k127_5048185_8 Lipopolysaccharide assembly protein A domain - - - 0.00001962 51.0
HFD1_k127_5058960_0 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 306.0
HFD1_k127_5058960_1 Belongs to the ompA family K03640 - - 0.00000000000000000000000003187 118.0
HFD1_k127_5106734_0 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 523.0
HFD1_k127_5106734_1 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000012 295.0
HFD1_k127_5106734_2 PRC-barrel domain - - - 0.000000000000000000000000000000000000000000000127 170.0
HFD1_k127_5106734_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000576 109.0
HFD1_k127_5106734_4 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000001006 68.0
HFD1_k127_5120398_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 325.0
HFD1_k127_5120398_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000001083 209.0
HFD1_k127_5120398_2 cobalamin biosynthesis protein - - - 0.000000000000000000000000004056 122.0
HFD1_k127_5120398_3 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.0000000001987 65.0
HFD1_k127_5121928_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 7.465e-275 854.0
HFD1_k127_5121928_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 565.0
HFD1_k127_5125599_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.412e-283 895.0
HFD1_k127_5125599_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 511.0
HFD1_k127_5125599_2 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 351.0
HFD1_k127_5125599_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 293.0
HFD1_k127_5125599_4 Lysin motif K06194 - - 0.000000000000000000000000000000000000000002963 164.0
HFD1_k127_5128922_0 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 373.0
HFD1_k127_5128922_1 small subunit K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 337.0
HFD1_k127_5128922_2 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000004627 165.0
HFD1_k127_5155694_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 1.15e-230 739.0
HFD1_k127_5155694_1 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 599.0
HFD1_k127_5155694_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 326.0
HFD1_k127_5155694_3 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001922 136.0
HFD1_k127_5155694_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001148 121.0
HFD1_k127_5156558_0 acetyl coenzyme A synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007833 274.0
HFD1_k127_5156558_1 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000001957 217.0
HFD1_k127_5156558_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000003874 185.0
HFD1_k127_5156558_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000003354 174.0
HFD1_k127_5168273_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 4.176e-218 688.0
HFD1_k127_5168273_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000005754 195.0
HFD1_k127_5168273_2 Polynucleotide kinase that can phosphorylate the 5'- hydroxyl groups of both single-stranded RNA (ssRNA) and single- stranded DNA (ssDNA). Exhibits a strong preference for ssRNA K06947 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019205,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0051731,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000001304 138.0
HFD1_k127_5199242_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.556e-205 649.0
HFD1_k127_5199242_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 429.0
HFD1_k127_5199242_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000003673 188.0
HFD1_k127_5199242_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000005717 185.0
HFD1_k127_5199242_4 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000001064 119.0
HFD1_k127_5199242_5 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000001415 69.0
HFD1_k127_5212179_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 1.122e-264 821.0
HFD1_k127_5212179_1 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000006568 237.0
HFD1_k127_5212179_2 Belongs to the FPP GGPP synthase family - - - 0.000000000000000000000000000000000000000000000000000000000002626 221.0
HFD1_k127_5212179_3 Pfam:Kce - - - 0.00000000000000000000000000000000000000007954 153.0
HFD1_k127_5212179_4 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000007929 149.0
HFD1_k127_5212179_6 Collagen triple helix repeat (20 copies) - - - 0.00000001611 64.0
HFD1_k127_5212179_7 YHS domain - - - 0.000001328 51.0
HFD1_k127_5222932_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 615.0
HFD1_k127_5222932_1 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 441.0
HFD1_k127_5222932_10 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000001937 55.0
HFD1_k127_5222932_12 Helix-turn-helix domain - - - 0.0001924 49.0
HFD1_k127_5222932_2 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 410.0
HFD1_k127_5222932_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 329.0
HFD1_k127_5222932_4 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000001083 224.0
HFD1_k127_5222932_5 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000001497 185.0
HFD1_k127_5222932_6 PFAM response regulator receiver - - - 0.0000000000000000000000000000001629 128.0
HFD1_k127_5222932_7 PFAM response regulator receiver - - - 0.000000000000000000000000000003073 126.0
HFD1_k127_5222932_8 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000008393 117.0
HFD1_k127_5229826_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008968 275.0
HFD1_k127_5229826_1 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000001197 207.0
HFD1_k127_5229826_2 general secretion pathway protein K02450 - - 0.00000000001411 68.0
HFD1_k127_5236935_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 319.0
HFD1_k127_5236935_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000001348 184.0
HFD1_k127_5248157_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 563.0
HFD1_k127_5248157_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 552.0
HFD1_k127_5248157_2 - - - - 0.00000000000000262 78.0
HFD1_k127_5255421_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.205e-240 754.0
HFD1_k127_5255421_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 551.0
HFD1_k127_5255421_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 393.0
HFD1_k127_5255421_3 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000002285 219.0
HFD1_k127_5331331_0 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 462.0
HFD1_k127_5331331_1 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000246 291.0
HFD1_k127_5331331_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001395 282.0
HFD1_k127_5331331_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000007329 207.0
HFD1_k127_5331331_4 diguanylate cyclase K21022 - 2.7.7.65 0.0000000000000000000000000000000000000000000000002032 190.0
HFD1_k127_5331331_5 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000005207 184.0
HFD1_k127_5331331_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000009601 175.0
HFD1_k127_5331331_7 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000006566 171.0
HFD1_k127_534074_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000002264 88.0
HFD1_k127_534074_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000001839 84.0
HFD1_k127_534074_2 - - - - 0.000004399 49.0
HFD1_k127_534074_3 PRC-barrel domain - - - 0.0005953 46.0
HFD1_k127_5391689_0 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 304.0
HFD1_k127_5391689_1 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000005061 149.0
HFD1_k127_5391689_2 Protein of unknown function (DUF721) - - - 0.0000000000000005506 84.0
HFD1_k127_5391689_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000002885 56.0
HFD1_k127_5392723_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 2.312e-211 669.0
HFD1_k127_5392723_1 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005189 243.0
HFD1_k127_5392723_2 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007644 247.0
HFD1_k127_5392723_3 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000003554 196.0
HFD1_k127_5392723_4 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000008942 181.0
HFD1_k127_5392723_5 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000002533 176.0
HFD1_k127_5392723_6 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000009435 99.0
HFD1_k127_5392723_7 Pyruvate phosphate dikinase - - - 0.000002135 52.0
HFD1_k127_5419857_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 597.0
HFD1_k127_5419857_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 601.0
HFD1_k127_5419857_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 587.0
HFD1_k127_5419857_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 430.0
HFD1_k127_5419857_4 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 405.0
HFD1_k127_5419857_5 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 293.0
HFD1_k127_5419857_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 287.0
HFD1_k127_5419857_7 PTS system fructose IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000000000000005611 158.0
HFD1_k127_5419857_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000004518 139.0
HFD1_k127_5419857_9 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000000000000005437 117.0
HFD1_k127_5426196_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 556.0
HFD1_k127_5426196_1 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.0001126 50.0
HFD1_k127_5450414_0 phosphoglycolate phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 325.0
HFD1_k127_5450414_1 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001317 281.0
HFD1_k127_5450414_2 Shikimate kinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000003297 183.0
HFD1_k127_5450414_3 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.000000000000000000000000000000000000000000009798 163.0
HFD1_k127_5450414_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000002328 166.0
HFD1_k127_5456610_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 556.0
HFD1_k127_5456610_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 333.0
HFD1_k127_5465295_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 8.259e-197 625.0
HFD1_k127_5465295_1 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 333.0
HFD1_k127_5465295_2 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000001481 239.0
HFD1_k127_5465295_3 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000004643 146.0
HFD1_k127_5465295_4 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000004737 76.0
HFD1_k127_5468011_0 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 554.0
HFD1_k127_5468011_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 421.0
HFD1_k127_5468011_2 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 317.0
HFD1_k127_5468011_3 Glycine cleavage H-protein - - - 0.0000000000000000000000003907 106.0
HFD1_k127_5468011_4 - - - - 0.0000000004168 72.0
HFD1_k127_5468011_5 transferase activity, transferring glycosyl groups - - - 0.000008596 49.0
HFD1_k127_5471620_1 PFAM Polysulphide reductase, NrfD K16294 - - 0.000000000000000000000000000000000000000000000000003648 194.0
HFD1_k127_5493934_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 455.0
HFD1_k127_5493934_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 443.0
HFD1_k127_5493934_2 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 340.0
HFD1_k127_5493934_3 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 307.0
HFD1_k127_5493934_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000533 246.0
HFD1_k127_5493934_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000001729 150.0
HFD1_k127_5493934_6 ParB-like nuclease domain - - - 0.000000000000000000000000000002628 126.0
HFD1_k127_549479_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1594.0
HFD1_k127_549479_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 423.0
HFD1_k127_549479_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000001611 198.0
HFD1_k127_549479_3 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000006203 130.0
HFD1_k127_5509183_0 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 390.0
HFD1_k127_5509183_1 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 317.0
HFD1_k127_5509183_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
HFD1_k127_5509183_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000009174 179.0
HFD1_k127_5509183_4 cytochrome c - - - 0.00000000000000006162 85.0
HFD1_k127_5509183_5 radical SAM domain protein - - - 0.0000000000002958 74.0
HFD1_k127_5509183_6 cystathionine K01760 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.8 0.0000000342 56.0
HFD1_k127_5533595_0 PFAM Glycosyl transferase, group 1 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 310.0
HFD1_k127_5533595_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007402 263.0
HFD1_k127_5533595_2 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000002577 126.0
HFD1_k127_5533595_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000001393 119.0
HFD1_k127_5533595_4 Hexapeptide repeat of succinyl-transferase K08280 - - 0.0000000000000000000000004835 113.0
HFD1_k127_5533595_5 Glycosyl transferases group 1 - - - 0.0000000000000000000005678 98.0
HFD1_k127_5533595_6 Methyltransferase domain - - - 0.00003299 53.0
HFD1_k127_5564462_0 Belongs to the catalase family K03781 - 1.11.1.6 0.0 1156.0
HFD1_k127_5564462_1 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 2.168e-218 690.0
HFD1_k127_5564462_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 353.0
HFD1_k127_5564462_3 Low affinity iron permease - - - 0.0000000000000000000000000000000000000000000704 164.0
HFD1_k127_5564462_4 Transglycosylase associated protein - - - 0.0000000000000000000000000005937 114.0
HFD1_k127_5564462_5 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000007313 112.0
HFD1_k127_5564462_6 ribonuclease BN K07058 - - 0.000000000000000000000001173 107.0
HFD1_k127_5564462_7 Membrane - - - 0.0000000000003104 71.0
HFD1_k127_5564462_8 PFAM YHS domain - - - 0.0000005795 59.0
HFD1_k127_5564462_9 Bacterial protein of unknown function (DUF937) - - - 0.00001608 50.0
HFD1_k127_5574067_0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000487 314.0
HFD1_k127_5574067_1 Histidine kinase - - - 0.0000000000000000000000000000000000001357 164.0
HFD1_k127_5574067_2 Histidine kinase - - - 0.000000000000000000000000000000000002859 160.0
HFD1_k127_5574067_3 S23 ribosomal protein - - - 0.000000000000000003572 85.0
HFD1_k127_557663_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 6.714e-275 857.0
HFD1_k127_557663_1 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 309.0
HFD1_k127_557663_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 305.0
HFD1_k127_557663_3 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 289.0
HFD1_k127_5578735_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 503.0
HFD1_k127_5578735_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 492.0
HFD1_k127_5578735_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 430.0
HFD1_k127_5578735_3 PFAM ABC transporter related K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 341.0
HFD1_k127_5637331_0 Transglycosylase - - - 0.0 1418.0
HFD1_k127_5637331_1 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000006046 211.0
HFD1_k127_5637331_2 Pfam Response regulator receiver - - - 0.0000000000000000000000009877 108.0
HFD1_k127_5637331_3 Pfam Response regulator receiver - - - 0.0000000000000000000001546 101.0
HFD1_k127_5637331_4 COG2217 Cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000009578 55.0
HFD1_k127_5637331_5 PRC-barrel domain - - - 0.00001061 54.0
HFD1_k127_5642772_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 297.0
HFD1_k127_5642772_1 ABC transporter, ATP-binding protein K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006304 270.0
HFD1_k127_5642772_2 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001718 263.0
HFD1_k127_5642772_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000001039 261.0
HFD1_k127_5642772_4 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001635 252.0
HFD1_k127_5642772_5 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000006521 238.0
HFD1_k127_5672229_0 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 318.0
HFD1_k127_5672229_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004453 278.0
HFD1_k127_5672229_2 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000005552 115.0
HFD1_k127_5672229_3 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000005683 93.0
HFD1_k127_5689032_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 5.923e-208 654.0
HFD1_k127_5689032_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 580.0
HFD1_k127_5689032_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000002368 63.0
HFD1_k127_5689032_3 protein N-acetylglucosaminyltransferase activity - - - 0.000002698 59.0
HFD1_k127_5690117_0 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 448.0
HFD1_k127_5690117_1 Ras family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009933 259.0
HFD1_k127_5690117_2 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000002246 246.0
HFD1_k127_5690117_3 Two component signalling adaptor domain K03408 - - 0.0007031 52.0
HFD1_k127_5699444_0 PFAM Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000003607 208.0
HFD1_k127_5699444_1 PFAM transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000005008 136.0
HFD1_k127_5701603_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 417.0
HFD1_k127_5701603_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 336.0
HFD1_k127_5701603_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000003176 156.0
HFD1_k127_5701603_11 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001258 147.0
HFD1_k127_5701603_12 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000164 138.0
HFD1_k127_5701603_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000005968 123.0
HFD1_k127_5701603_14 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001004 111.0
HFD1_k127_5701603_15 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000008188 107.0
HFD1_k127_5701603_16 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000927 76.0
HFD1_k127_5701603_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 293.0
HFD1_k127_5701603_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001739 251.0
HFD1_k127_5701603_4 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001173 242.0
HFD1_k127_5701603_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000009439 218.0
HFD1_k127_5701603_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000004821 198.0
HFD1_k127_5701603_7 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000009153 178.0
HFD1_k127_5701603_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000009106 173.0
HFD1_k127_5701603_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000006166 163.0
HFD1_k127_5702305_0 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000622 172.0
HFD1_k127_5702305_1 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000006042 167.0
HFD1_k127_5702305_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000001312 157.0
HFD1_k127_5702305_4 PFAM ribonuclease II K01147 - 3.1.13.1 0.000001036 51.0
HFD1_k127_5702487_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 8.887e-308 973.0
HFD1_k127_5702487_1 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 6.211e-266 828.0
HFD1_k127_5702487_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 342.0
HFD1_k127_5702487_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 316.0
HFD1_k127_5702487_4 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003326 246.0
HFD1_k127_5702487_5 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000002471 152.0
HFD1_k127_5702487_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000006469 134.0
HFD1_k127_5702487_7 Endonuclease/Exonuclease/phosphatase family - - - 0.000002156 61.0
HFD1_k127_573055_0 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 373.0
HFD1_k127_573055_1 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 330.0
HFD1_k127_573055_2 Radical_SAM C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002963 275.0
HFD1_k127_573055_3 PFAM ApbE family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000333 233.0
HFD1_k127_573055_4 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000001705 234.0
HFD1_k127_573055_5 electron transfer activity K00428 - 1.11.1.5 0.000000000000000004181 87.0
HFD1_k127_573055_6 ligase activity - - - 0.0000000000000002606 86.0
HFD1_k127_5731565_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 608.0
HFD1_k127_5731565_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 493.0
HFD1_k127_5731565_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 423.0
HFD1_k127_5750957_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 4.472e-263 816.0
HFD1_k127_5750957_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 2.619e-240 750.0
HFD1_k127_5750957_2 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 292.0
HFD1_k127_5750957_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 300.0
HFD1_k127_5750957_4 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000009855 243.0
HFD1_k127_5750957_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000001249 85.0
HFD1_k127_5750957_6 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) - - - 0.0000000000000000425 83.0
HFD1_k127_576581_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0 1118.0
HFD1_k127_576581_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 556.0
HFD1_k127_576581_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000007008 171.0
HFD1_k127_576581_11 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000006228 178.0
HFD1_k127_576581_12 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000006275 128.0
HFD1_k127_576581_13 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000009988 124.0
HFD1_k127_576581_14 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000001228 119.0
HFD1_k127_576581_15 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001817 108.0
HFD1_k127_576581_16 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000002708 106.0
HFD1_k127_576581_17 - - - - 0.000000000001237 73.0
HFD1_k127_576581_2 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 520.0
HFD1_k127_576581_3 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 359.0
HFD1_k127_576581_4 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 305.0
HFD1_k127_576581_5 Phosphomethylpyrimidine kinase K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 299.0
HFD1_k127_576581_6 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000001792 228.0
HFD1_k127_576581_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000003816 223.0
HFD1_k127_576581_8 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000207 207.0
HFD1_k127_576581_9 SAM-dependent RNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000003995 206.0
HFD1_k127_5768011_0 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000004455 185.0
HFD1_k127_5768011_1 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000001087 179.0
HFD1_k127_5768011_2 PFAM ABC transporter K02052 - - 0.000000000000000000000000000000000001253 142.0
HFD1_k127_5768011_3 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000005475 138.0
HFD1_k127_577493_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 550.0
HFD1_k127_577493_1 PFAM AAA ATPase central domain protein K06027 - 3.6.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 480.0
HFD1_k127_577493_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 453.0
HFD1_k127_577493_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 351.0
HFD1_k127_577493_4 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000003111 205.0
HFD1_k127_577493_5 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000004926 104.0
HFD1_k127_5784369_0 E1-E2 ATPase K01533,K01534,K17686 - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 497.0
HFD1_k127_5784369_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 359.0
HFD1_k127_5784369_10 - - - - 0.00001818 50.0
HFD1_k127_5784369_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 339.0
HFD1_k127_5784369_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000002008 236.0
HFD1_k127_5784369_4 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000003682 210.0
HFD1_k127_5784369_5 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000002634 127.0
HFD1_k127_5784369_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000001926 122.0
HFD1_k127_5784369_7 Rubrerythrin - - - 0.000000000000000000000001419 109.0
HFD1_k127_5784369_8 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000001498 100.0
HFD1_k127_5784369_9 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000001001 94.0
HFD1_k127_5803058_0 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 542.0
HFD1_k127_5803058_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000005703 256.0
HFD1_k127_581064_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.105e-297 929.0
HFD1_k127_581064_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 393.0
HFD1_k127_581064_10 Protein of unknown function (DUF3108) - - - 0.00000000001563 74.0
HFD1_k127_581064_2 mannitol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 342.0
HFD1_k127_581064_3 transporter solute receptor, DctP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 325.0
HFD1_k127_581064_4 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 317.0
HFD1_k127_581064_5 PFAM fumarate reductase succinate dehydrogenase flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 312.0
HFD1_k127_581064_6 Tetracycline repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003884 237.0
HFD1_k127_581064_7 Protein of unknown function (DUF2848) - - - 0.00000000000000000000000000000000000000000000000000000000000000226 231.0
HFD1_k127_581064_8 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.00000000000000000000000000000000003424 148.0
HFD1_k127_581064_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000002827 81.0
HFD1_k127_5816769_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.049e-279 886.0
HFD1_k127_5816769_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001488 273.0
HFD1_k127_5816769_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000003372 231.0
HFD1_k127_5816769_3 - - - - 0.0000000000000000000000000000000000000000000000000000000572 209.0
HFD1_k127_5816769_4 Protease prsW family - - - 0.00000000000000000000000000000000000000000001432 172.0
HFD1_k127_5816769_5 Protein of unknown function (DUF434) - - - 0.0000000000000000000000000001258 117.0
HFD1_k127_5816769_6 - - - - 0.000000000000001298 80.0
HFD1_k127_5816769_7 Glutaredoxin K03676,K04771 - 3.4.21.107 0.00000000000005867 73.0
HFD1_k127_5821193_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1691.0
HFD1_k127_5821193_1 Family membership - - - 1.241e-211 698.0
HFD1_k127_5821193_10 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000002513 171.0
HFD1_k127_5821193_11 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000000000000000000000000006697 134.0
HFD1_k127_5821193_12 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000002722 114.0
HFD1_k127_5821193_13 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000689 107.0
HFD1_k127_5821193_14 - - - - 0.00000001368 66.0
HFD1_k127_5821193_15 Protein of unknown function K09800 - - 0.000007749 58.0
HFD1_k127_5821193_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 497.0
HFD1_k127_5821193_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 462.0
HFD1_k127_5821193_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 441.0
HFD1_k127_5821193_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 430.0
HFD1_k127_5821193_6 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 388.0
HFD1_k127_5821193_7 Alpha/beta hydrolase family K16050 - 3.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 302.0
HFD1_k127_5821193_8 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002852 256.0
HFD1_k127_5821193_9 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000003361 191.0
HFD1_k127_5833138_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 503.0
HFD1_k127_5833138_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 389.0
HFD1_k127_5833138_2 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 301.0
HFD1_k127_5833138_3 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 300.0
HFD1_k127_5833138_4 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000833 113.0
HFD1_k127_5833138_5 RNA-binding protein - - - 0.000000000000000000000009689 103.0
HFD1_k127_5833138_6 deoxyhypusine monooxygenase activity - - - 0.0000000000009736 78.0
HFD1_k127_5833138_7 - - - - 0.0000001254 61.0
HFD1_k127_5833138_9 Ribbon-helix-helix domain - - - 0.000001952 52.0
HFD1_k127_5852599_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 492.0
HFD1_k127_5852599_1 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 414.0
HFD1_k127_5852599_2 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 407.0
HFD1_k127_58606_0 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 326.0
HFD1_k127_58606_1 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000001964 151.0
HFD1_k127_58606_2 Yip1 domain - - - 0.0000000000000000000000001993 120.0
HFD1_k127_592089_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 614.0
HFD1_k127_592089_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 353.0
HFD1_k127_592089_2 FMN binding - - - 0.0000000000000000000000000000000007155 137.0
HFD1_k127_592089_3 Domain of unknown function (DUF1330) - - - 0.00000000000728 66.0
HFD1_k127_5934275_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 590.0
HFD1_k127_5934275_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 572.0
HFD1_k127_5934275_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000001226 210.0
HFD1_k127_5934275_3 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000003291 154.0
HFD1_k127_5934275_4 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000008595 152.0
HFD1_k127_5934275_5 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000002034 131.0
HFD1_k127_5934275_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000003877 122.0
HFD1_k127_5934275_7 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000001335 111.0
HFD1_k127_5934275_8 Single-strand binding protein family K03111 - - 0.0002028 49.0
HFD1_k127_5937757_0 MMPL family K07003 - - 7.685e-233 757.0
HFD1_k127_5937757_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 514.0
HFD1_k127_5937757_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 347.0
HFD1_k127_5937757_3 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000002173 168.0
HFD1_k127_5937757_4 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000001054 141.0
HFD1_k127_5937757_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000008672 114.0
HFD1_k127_5939000_0 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001229 273.0
HFD1_k127_5939000_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000001888 222.0
HFD1_k127_5939000_2 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000006149 61.0
HFD1_k127_5943221_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.866e-314 976.0
HFD1_k127_5943221_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 3.665e-255 799.0
HFD1_k127_5943221_2 Osmosensitive K channel histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 493.0
HFD1_k127_5943221_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 395.0
HFD1_k127_5943221_4 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000008227 217.0
HFD1_k127_5943221_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000002103 214.0
HFD1_k127_5954286_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1094.0
HFD1_k127_5954286_1 ABC transporter transmembrane region K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 594.0
HFD1_k127_5954286_2 ABC transporter transmembrane region K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 529.0
HFD1_k127_5954286_3 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 329.0
HFD1_k127_5954286_4 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 299.0
HFD1_k127_5954286_5 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000001056 231.0
HFD1_k127_5954286_6 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000001141 199.0
HFD1_k127_5954286_7 exodeoxyribonuclease I activity - - - 0.00000000000001726 75.0
HFD1_k127_6006602_0 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 385.0
HFD1_k127_6006602_1 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 348.0
HFD1_k127_6006602_2 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001329 242.0
HFD1_k127_6006602_3 Flavin containing amine oxidoreductase - - - 0.000004131 53.0
HFD1_k127_6011533_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 310.0
HFD1_k127_6011533_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 290.0
HFD1_k127_6011533_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000001225 223.0
HFD1_k127_6011533_3 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000125 208.0
HFD1_k127_6011533_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000116 162.0
HFD1_k127_6028557_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 345.0
HFD1_k127_6028557_1 PFAM Integrase K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 306.0
HFD1_k127_6028557_2 transposase activity K07483 - - 0.00000000000000000000003942 101.0
HFD1_k127_60412_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001895 277.0
HFD1_k127_60412_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001086 274.0
HFD1_k127_60412_2 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002425 250.0
HFD1_k127_60412_3 L-lysine catabolic process to acetate K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000001203 214.0
HFD1_k127_60412_4 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000008924 210.0
HFD1_k127_60412_5 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000002326 209.0
HFD1_k127_60412_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000156 143.0
HFD1_k127_6043461_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.925e-223 707.0
HFD1_k127_6043461_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 477.0
HFD1_k127_6043461_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 439.0
HFD1_k127_6043461_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003988 276.0
HFD1_k127_6043461_4 Cytidylate kinase K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000003883 245.0
HFD1_k127_6043461_5 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000126 217.0
HFD1_k127_6076591_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 6.028e-218 690.0
HFD1_k127_6076591_1 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 468.0
HFD1_k127_6076591_2 histidine kinase, HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000006589 193.0
HFD1_k127_6076591_3 - - - - 0.000000000000000000000000000000267 128.0
HFD1_k127_6087730_0 Rhodanese Homology Domain K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 469.0
HFD1_k127_6087730_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 422.0
HFD1_k127_6087730_10 Phage-related replication protein - - - 0.000000000000000000000000000000000000000001439 162.0
HFD1_k127_6087730_11 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000004788 156.0
HFD1_k127_6087730_12 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000001644 160.0
HFD1_k127_6087730_13 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000004022 148.0
HFD1_k127_6087730_14 PFAM Class I peptide chain release factor - - - 0.00000000000000000000000000000000000003887 146.0
HFD1_k127_6087730_16 Cupin domain K11312 - - 0.000000000000000000000000000000000001248 141.0
HFD1_k127_6087730_17 PFAM SpoVT AbrB K07172 - - 0.000000000000000000000000000000000003672 139.0
HFD1_k127_6087730_18 COG0084 Mg-dependent DNase K03424 - - 0.0000000000000000000000000000001353 134.0
HFD1_k127_6087730_19 Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000001661 79.0
HFD1_k127_6087730_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 407.0
HFD1_k127_6087730_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 357.0
HFD1_k127_6087730_4 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001908 280.0
HFD1_k127_6087730_5 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000252 257.0
HFD1_k127_6087730_6 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000001999 255.0
HFD1_k127_6087730_7 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000003724 196.0
HFD1_k127_6087730_8 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000002393 198.0
HFD1_k127_6087730_9 Oxidoreductase molybdopterin binding domain K07147 - - 0.0000000000000000000000000000000000000000000000005803 181.0
HFD1_k127_6090365_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.704e-259 817.0
HFD1_k127_6090365_1 phosphate ion binding K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 354.0
HFD1_k127_6090365_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000004578 174.0
HFD1_k127_6090365_3 - - - - 0.0000000000000000001178 91.0
HFD1_k127_6094997_0 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001166 269.0
HFD1_k127_6094997_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003096 246.0
HFD1_k127_6094997_2 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000003812 201.0
HFD1_k127_6094997_3 ABC-type branched-chain amino acid transport K07121 - - 0.00000000000000000000000000000000003725 152.0
HFD1_k127_6094997_4 Thiamine-binding protein - - - 0.000000000000000000000000000003892 124.0
HFD1_k127_6106512_0 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 609.0
HFD1_k127_6106512_1 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007659 276.0
HFD1_k127_6106512_2 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000009122 225.0
HFD1_k127_6106512_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000004534 159.0
HFD1_k127_6112795_0 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000001978 243.0
HFD1_k127_6112795_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000003383 244.0
HFD1_k127_6112795_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000003747 190.0
HFD1_k127_6112795_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000004531 149.0
HFD1_k127_6122112_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1459.0
HFD1_k127_6122112_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 4.669e-212 667.0
HFD1_k127_6122112_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 478.0
HFD1_k127_6122112_3 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 293.0
HFD1_k127_6122112_4 GXGXG motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000196 295.0
HFD1_k127_6122112_5 Glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000002941 238.0
HFD1_k127_6122112_6 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000596 191.0
HFD1_k127_6122112_7 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000003762 102.0
HFD1_k127_6122112_8 - - - - 0.0000003449 61.0
HFD1_k127_6122112_9 Belongs to the glutamate synthase family - - - 0.0001233 46.0
HFD1_k127_6138521_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.868e-280 870.0
HFD1_k127_6138521_1 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 324.0
HFD1_k127_6138521_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007879 271.0
HFD1_k127_6138521_3 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000001508 201.0
HFD1_k127_6138521_4 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000001929 141.0
HFD1_k127_6138521_5 Endonuclease containing a URI domain K07461 - - 0.0000000000000000007532 89.0
HFD1_k127_6173923_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 456.0
HFD1_k127_6173923_1 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000002978 220.0
HFD1_k127_6173923_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000003137 162.0
HFD1_k127_6173923_3 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000001755 145.0
HFD1_k127_6173923_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000002918 136.0
HFD1_k127_6173923_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000001264 124.0
HFD1_k127_6202349_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 8.656e-236 742.0
HFD1_k127_6202349_1 Protein export membrane protein K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 567.0
HFD1_k127_6202349_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 308.0
HFD1_k127_6202349_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 305.0
HFD1_k127_6202349_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001521 211.0
HFD1_k127_6202349_5 Glycine cleavage system H protein K02437 - - 0.00000000000000000000000000000000000000000000001683 174.0
HFD1_k127_6202349_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000003609 169.0
HFD1_k127_6212046_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000002302 238.0
HFD1_k127_6212046_2 - - - - 0.0001452 49.0
HFD1_k127_6212046_3 - - - - 0.0006472 48.0
HFD1_k127_6220998_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.732e-200 630.0
HFD1_k127_6220998_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 607.0
HFD1_k127_6220998_2 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 552.0
HFD1_k127_6220998_3 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 520.0
HFD1_k127_6220998_4 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 399.0
HFD1_k127_6220998_5 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 307.0
HFD1_k127_6220998_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000002672 244.0
HFD1_k127_622968_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 9.381e-257 803.0
HFD1_k127_622968_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.365e-197 627.0
HFD1_k127_622968_2 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.000000000000000000000000000000000000000005153 159.0
HFD1_k127_622968_3 - - - - 0.0000000000000000000001516 103.0
HFD1_k127_622968_4 binding domain protein - - - 0.00002388 49.0
HFD1_k127_622968_5 Nitroreductase family - - - 0.0007303 48.0
HFD1_k127_62441_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 459.0
HFD1_k127_62441_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 440.0
HFD1_k127_6246927_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 9.402e-213 681.0
HFD1_k127_6246927_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 454.0
HFD1_k127_6246927_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000001504 231.0
HFD1_k127_6246927_3 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000000002064 199.0
HFD1_k127_6246927_4 THUMP - - - 0.0000000000000000000000000000001377 130.0
HFD1_k127_6246927_5 Pfam Response regulator receiver - - - 0.0000000000000000000000000001605 119.0
HFD1_k127_6277891_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1092.0
HFD1_k127_6277891_1 PFAM molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000756 284.0
HFD1_k127_6277891_2 helix_turn_helix, Lux Regulon K02282 - - 0.000000000000000000000000000000000000000000000000000000000008296 214.0
HFD1_k127_6277891_3 PRC-barrel domain - - - 0.000000000000000000000000000000000000000000008486 166.0
HFD1_k127_6277891_4 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000003453 140.0
HFD1_k127_6277891_5 CsbD-like - - - 0.000000000000000000000003176 103.0
HFD1_k127_6277891_6 unusual protein kinase K03688 - - 0.0000000000001675 72.0
HFD1_k127_63122_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 361.0
HFD1_k127_63122_1 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 292.0
HFD1_k127_63122_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000000000001437 189.0
HFD1_k127_63122_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000003933 179.0
HFD1_k127_63122_4 - - - - 0.0000000000000003914 79.0
HFD1_k127_6317773_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 458.0
HFD1_k127_632985_0 COG0618 Exopolyphosphatase-related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 310.0
HFD1_k127_632985_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001257 248.0
HFD1_k127_632985_2 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000007742 213.0
HFD1_k127_632985_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000001383 163.0
HFD1_k127_632985_4 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000003726 154.0
HFD1_k127_632985_5 oxidoreductase activity, acting on diphenols and related substances as donors K02636 - 1.10.9.1 0.00000000000000000000000006564 113.0
HFD1_k127_6338964_0 PFAM Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 407.0
HFD1_k127_6338964_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 314.0
HFD1_k127_6338964_2 acetyltransferase - - - 0.000000000000000000000000000000000000000195 155.0
HFD1_k127_6338964_3 Glycosyl transferase K13693 - 2.4.1.266 0.000000000000518 72.0
HFD1_k127_6362130_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 416.0
HFD1_k127_6362130_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003807 282.0
HFD1_k127_6362130_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003576 258.0
HFD1_k127_6373423_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 431.0
HFD1_k127_6373423_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 312.0
HFD1_k127_6373423_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00034,K00038,K00046 - 1.1.1.47,1.1.1.53,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000835 231.0
HFD1_k127_6373423_3 Putative cyclase - - - 0.00000000000000000000000000000000000004474 148.0
HFD1_k127_6375700_0 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000001242 241.0
HFD1_k127_6375700_1 COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000001205 190.0
HFD1_k127_6375700_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000118 121.0
HFD1_k127_6384725_0 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 432.0
HFD1_k127_6384725_1 transmembrane transport - - - 0.00000000000000000000000000000000000000003581 161.0
HFD1_k127_6394723_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 2.971e-233 736.0
HFD1_k127_6394723_1 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 621.0
HFD1_k127_6394723_10 Phospholipid methyltransferase - - - 0.0000000000000000007234 94.0
HFD1_k127_6394723_11 kinase activity - - - 0.00000000000000002101 96.0
HFD1_k127_6394723_12 Psort location Cytoplasmic, score 8.96 - - - 0.000000006852 68.0
HFD1_k127_6394723_2 AAA domain K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 440.0
HFD1_k127_6394723_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 454.0
HFD1_k127_6394723_4 PFAM Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 396.0
HFD1_k127_6394723_5 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003304 281.0
HFD1_k127_6394723_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000002488 238.0
HFD1_k127_6394723_7 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000001528 213.0
HFD1_k127_6394723_8 serine threonine protein kinase - - - 0.00000000000000000000000001189 117.0
HFD1_k127_6394723_9 Uncharacterized protein family UPF0054 K07042 - - 0.000000000000000000000001207 109.0
HFD1_k127_6401178_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 7.511e-199 627.0
HFD1_k127_6401178_1 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 387.0
HFD1_k127_6429406_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 381.0
HFD1_k127_6429406_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 327.0
HFD1_k127_6429406_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000008779 212.0
HFD1_k127_6429406_3 HAD-superfamily hydrolase, subfamily IB K08966 - 3.1.3.87 0.000000000000000000000000000000000000000000000000000006482 197.0
HFD1_k127_6429406_4 PFAM conserved K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000225 168.0
HFD1_k127_6429406_5 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000003588 126.0
HFD1_k127_6429406_6 Flavin containing amine oxidoreductase - - - 0.00000009637 64.0
HFD1_k127_6435893_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 7.737e-263 838.0
HFD1_k127_6435893_1 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 536.0
HFD1_k127_6435893_2 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000001659 181.0
HFD1_k127_6435893_3 nucleotidyltransferase activity K00984 - 2.7.7.47 0.000000000000000000000000000000001835 136.0
HFD1_k127_6435893_4 HEPN domain - - - 0.0000000000000000008844 92.0
HFD1_k127_6435893_5 PFAM import inner membrane translocase, subunit Tim44 - - - 0.00000000000000001374 82.0
HFD1_k127_6435893_6 - - - - 0.00000000000000007526 87.0
HFD1_k127_6435893_7 Helix-turn-helix domain - - - 0.0000000000000009608 83.0
HFD1_k127_6467910_0 membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 408.0
HFD1_k127_6467910_1 - - - - 0.0000000000000000000000000000000000000000000003149 174.0
HFD1_k127_6467910_2 - - - - 0.0000000000000000006507 94.0
HFD1_k127_6467910_3 domain, Protein - - - 0.00000000000003282 87.0
HFD1_k127_6467910_4 PhoD-like phosphatase K07004 - - 0.00000001481 68.0
HFD1_k127_6478713_0 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 448.0
HFD1_k127_6478713_1 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000363 214.0
HFD1_k127_6478713_2 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000004478 157.0
HFD1_k127_6499370_0 Coenzyme F420 hydrogenase dehydrogenase, beta subunit C terminus K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002776 287.0
HFD1_k127_6499370_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000003283 208.0
HFD1_k127_6499370_2 Zn-dependent hydrolases including glyoxylases-like protein - - - 0.00000000000000000007552 95.0
HFD1_k127_6499370_3 Protein of unknown function (DUF1161) - - - 0.00000000000000001277 84.0
HFD1_k127_6506787_0 Heat shock 70 kDa protein K04043 - - 2.794e-293 907.0
HFD1_k127_6506787_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 349.0
HFD1_k127_6506787_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 346.0
HFD1_k127_6506787_3 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 333.0
HFD1_k127_6506787_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000003417 152.0
HFD1_k127_6516599_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.0 1118.0
HFD1_k127_6516599_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 551.0
HFD1_k127_6516599_2 4 iron, 4 sulfur cluster binding K03522,K13795,K15511,K19516 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 298.0
HFD1_k127_6516599_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000005105 163.0
HFD1_k127_6516599_4 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000001354 124.0
HFD1_k127_6516599_5 Putative transposon-encoded protein (DUF2080) - - - 0.00000000000000000231 85.0
HFD1_k127_6516599_6 PRC-barrel domain - - - 0.00000000000148 73.0
HFD1_k127_6522878_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 536.0
HFD1_k127_6522878_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 404.0
HFD1_k127_6522878_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 310.0
HFD1_k127_6522878_3 curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000001697 166.0
HFD1_k127_6536949_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 628.0
HFD1_k127_6536949_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 535.0
HFD1_k127_6536949_2 8-oxoguanine DNA glycosylase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000003043 217.0
HFD1_k127_6536949_3 Elongation factor Tu domain 2 K03833 - - 0.00000000000000000000000000000000000000000004565 168.0
HFD1_k127_6536949_4 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000001093 139.0
HFD1_k127_6536949_5 Anaphase-promoting complex, cyclosome, subunit 3 K03350 GO:0000070,GO:0000151,GO:0000152,GO:0000278,GO:0000280,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005680,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007049,GO:0007050,GO:0007059,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0022402,GO:0030071,GO:0030163,GO:0031145,GO:0031331,GO:0031461,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032446,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045732,GO:0045786,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045930,GO:0045931,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051276,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0071849,GO:0071850,GO:0071851,GO:0090068,GO:0097159,GO:0098813,GO:0140014,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903047,GO:1903052,GO:1903364,GO:1905818,GO:1905820,GO:1990234,GO:2001252 - 0.0000258 54.0
HFD1_k127_6551225_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00184 - - 9.437e-243 782.0
HFD1_k127_6551225_1 cytochrome c oxidase K00404 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 526.0
HFD1_k127_6551225_10 - - - - 0.00004024 51.0
HFD1_k127_6551225_11 Cytochrome oxidase maturation protein - - - 0.0004156 47.0
HFD1_k127_6551225_2 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 524.0
HFD1_k127_6551225_3 cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 449.0
HFD1_k127_6551225_4 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000408 233.0
HFD1_k127_6551225_5 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000005462 198.0
HFD1_k127_6551225_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000001019 119.0
HFD1_k127_6551225_7 Protein of unknown function (DUF3341) - - - 0.000000000000000000001199 102.0
HFD1_k127_6551225_8 PFAM Ferric reductase like transmembrane component K09792 - - 0.00000000000000000003174 97.0
HFD1_k127_6553873_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 410.0
HFD1_k127_6553873_1 PFAM NAD dependent epimerase dehydratase family K01709,K01710,K01784 - 4.2.1.45,4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 396.0
HFD1_k127_6553873_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 354.0
HFD1_k127_6553873_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001211 254.0
HFD1_k127_6553873_4 PFAM Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002106 246.0
HFD1_k127_6553873_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000984 105.0
HFD1_k127_6553873_6 Male sterility protein K01784 - 5.1.3.2 0.000000000000002858 78.0
HFD1_k127_6553873_7 protein involved in methicillin resistance - - - 0.0000000000001086 82.0
HFD1_k127_6553873_8 ubiE/COQ5 methyltransferase family - - - 0.0000003401 60.0
HFD1_k127_6561229_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 501.0
HFD1_k127_6561229_1 PFAM iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 317.0
HFD1_k127_6561229_2 SCP-2 sterol transfer family - - - 0.000000000000000000000001541 108.0
HFD1_k127_6561229_3 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000003596 90.0
HFD1_k127_6564918_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.839e-242 758.0
HFD1_k127_6564918_1 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.101e-225 709.0
HFD1_k127_6564918_2 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008097 588.0
HFD1_k127_6564918_3 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 376.0
HFD1_k127_6571294_0 anaphase-promoting complex-dependent catabolic process - - - 0.000000000000000000000000000000000000000000000000001034 186.0
HFD1_k127_6571294_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000004689 179.0
HFD1_k127_6571294_2 exodeoxyribonuclease I activity - - - 0.00007303 52.0
HFD1_k127_6593058_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 1.931e-292 921.0
HFD1_k127_6593058_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.642e-256 808.0
HFD1_k127_6593058_2 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 462.0
HFD1_k127_6593058_3 Tyrosine recombinase XerD K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 314.0
HFD1_k127_6593058_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000004564 179.0
HFD1_k127_6593058_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000001002 96.0
HFD1_k127_6595468_0 Cytochrome c554 and c-prime - - - 9.612e-297 931.0
HFD1_k127_6595468_1 PFAM sulfatase K01130 - 3.1.6.1 3.544e-246 769.0
HFD1_k127_6595468_10 Domain of unknown function (DUF4381) - - - 0.00000000000000000000000000000003096 132.0
HFD1_k127_6595468_11 - - - - 0.000000000000000000000000000001287 136.0
HFD1_k127_6595468_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11527 - 2.7.13.3 4.935e-194 660.0
HFD1_k127_6595468_3 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 495.0
HFD1_k127_6595468_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 454.0
HFD1_k127_6595468_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 338.0
HFD1_k127_6595468_6 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 338.0
HFD1_k127_6595468_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001289 254.0
HFD1_k127_6595468_8 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00000000000000000000000000000000001455 154.0
HFD1_k127_6595468_9 phosphorelay signal transduction system K13599 - - 0.00000000000000000000000000000000001948 154.0
HFD1_k127_6623210_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 498.0
HFD1_k127_6623210_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 415.0
HFD1_k127_6623210_2 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000001612 149.0
HFD1_k127_6635139_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 360.0
HFD1_k127_6635139_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000003431 123.0
HFD1_k127_6635139_2 domain protein - - - 0.0000000000000000000000002449 114.0
HFD1_k127_6658573_0 - - - - 0.0000000000002 76.0
HFD1_k127_6658573_2 PFAM Transglycosylase SLT domain K08309 - - 0.00002833 54.0
HFD1_k127_6660737_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 393.0
HFD1_k127_6660737_1 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 330.0
HFD1_k127_6660737_2 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000006943 216.0
HFD1_k127_6660737_3 Cellulase (glycosyl hydrolase family 5) - - - 0.00000000000000002151 94.0
HFD1_k127_6662989_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 528.0
HFD1_k127_6662989_1 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 361.0
HFD1_k127_6662989_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000001358 98.0
HFD1_k127_6662989_3 Protein of unknown function (DUF2905) - - - 0.00000000000000000007367 91.0
HFD1_k127_6664104_0 PFAM Pyruvate carboxyltransferase - - - 8.035e-276 859.0
HFD1_k127_6664104_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.476e-239 751.0
HFD1_k127_6664104_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 512.0
HFD1_k127_6664104_3 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 385.0
HFD1_k127_6664104_4 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 335.0
HFD1_k127_6664104_5 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001099 268.0
HFD1_k127_666740_0 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 585.0
HFD1_k127_666740_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002029 263.0
HFD1_k127_666740_2 denitrification pathway - - - 0.0000000000000000000006581 100.0
HFD1_k127_666740_3 Regulatory protein, FmdB family - - - 0.000002576 55.0
HFD1_k127_6671408_0 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 1.557e-199 629.0
HFD1_k127_6671408_1 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 423.0
HFD1_k127_6671408_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 387.0
HFD1_k127_6671408_3 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003181 245.0
HFD1_k127_6671408_4 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000004048 171.0
HFD1_k127_6671408_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000003406 62.0
HFD1_k127_6686596_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 520.0
HFD1_k127_6686596_1 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 480.0
HFD1_k127_6686596_2 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 337.0
HFD1_k127_6686596_3 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000002416 186.0
HFD1_k127_6686596_4 Ribosomal protein S20 K02968 - - 0.00000000000002536 76.0
HFD1_k127_6699246_0 extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 376.0
HFD1_k127_6699246_1 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000281 252.0
HFD1_k127_6699246_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001359 246.0
HFD1_k127_6699246_3 branched-chain amino acid ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000004737 243.0
HFD1_k127_6699246_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000002016 238.0
HFD1_k127_6699246_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000002432 224.0
HFD1_k127_6699246_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000006022 225.0
HFD1_k127_6699246_7 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000001461 170.0
HFD1_k127_672576_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 378.0
HFD1_k127_672576_1 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000002474 254.0
HFD1_k127_672576_2 transport system periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000003018 227.0
HFD1_k127_672576_3 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000347 71.0
HFD1_k127_6728466_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 1.392e-262 822.0
HFD1_k127_6728466_1 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 565.0
HFD1_k127_6728466_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 432.0
HFD1_k127_6728466_3 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 362.0
HFD1_k127_6728466_4 PFAM CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000000009283 169.0
HFD1_k127_6728466_5 uridine 5'-monophosphate synthase K13421 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0016036,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896,GO:0051716,GO:0071496 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000001098 141.0
HFD1_k127_6747881_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 6.062e-218 692.0
HFD1_k127_6747881_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 405.0
HFD1_k127_6747881_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000002774 228.0
HFD1_k127_6750780_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 474.0
HFD1_k127_6750780_1 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001056 260.0
HFD1_k127_6750780_2 HNH endonuclease - - - 0.0000000001082 65.0
HFD1_k127_6756965_0 phosphoribosyltransferase. Source PGD - - - 2.917e-203 645.0
HFD1_k127_6756965_1 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 426.0
HFD1_k127_6756965_2 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 299.0
HFD1_k127_6756965_3 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000001432 217.0
HFD1_k127_6756965_4 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000001696 151.0
HFD1_k127_6756965_5 cell redox homeostasis K02199 - - 0.00000000000000000000000000000002268 132.0
HFD1_k127_6756965_6 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000009346 100.0
HFD1_k127_6756965_7 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000009605 77.0
HFD1_k127_6756965_8 Helix-turn-helix domain - - - 0.0000000001522 69.0
HFD1_k127_6756965_9 Domain of unknown function (DUF4115) - - - 0.0000000002066 69.0
HFD1_k127_6795167_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 365.0
HFD1_k127_6795167_1 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 349.0
HFD1_k127_6795167_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 342.0
HFD1_k127_6795167_3 COG0006 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 317.0
HFD1_k127_6795167_4 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 306.0
HFD1_k127_6795167_5 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004293 258.0
HFD1_k127_6795167_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005711 256.0
HFD1_k127_6795167_7 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000003318 176.0
HFD1_k127_6795167_8 FCD - - - 0.0000000000000000000000000009716 121.0
HFD1_k127_6807050_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 448.0
HFD1_k127_6807050_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002113 249.0
HFD1_k127_6807050_2 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000002357 121.0
HFD1_k127_6807050_3 - - - - 0.000000000000000000000007612 105.0
HFD1_k127_6807050_4 - - - - 0.00000000003115 64.0
HFD1_k127_6807050_5 TspO/MBR family K05770 - - 0.00000009556 58.0
HFD1_k127_6807050_6 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0003314 43.0
HFD1_k127_6807159_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.014e-236 747.0
HFD1_k127_6807159_1 Four helix bundle sensory module for signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001785 249.0
HFD1_k127_6807159_2 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 0.0000000000000001336 79.0
HFD1_k127_6810788_0 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 473.0
HFD1_k127_6810788_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 425.0
HFD1_k127_6810788_11 FCD - - - 0.000146 48.0
HFD1_k127_6810788_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 360.0
HFD1_k127_6810788_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001926 251.0
HFD1_k127_6810788_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000009476 204.0
HFD1_k127_6810788_5 - - - - 0.0000000000000000000000000000000000000000000000003037 179.0
HFD1_k127_6810788_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000005734 138.0
HFD1_k127_6810788_7 YacP-like NYN domain K06962 - - 0.00000000000000000000000000000001296 132.0
HFD1_k127_6810788_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000002741 86.0
HFD1_k127_6810788_9 - - - - 0.0000000639 57.0
HFD1_k127_684301_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 530.0
HFD1_k127_684301_1 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 323.0
HFD1_k127_684301_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 287.0
HFD1_k127_684301_3 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000001218 192.0
HFD1_k127_684301_4 PFAM Amidohydrolase family K01443 - 3.5.1.25 0.00000004857 57.0
HFD1_k127_684301_5 Pfam:DUF1049 - - - 0.0001427 48.0
HFD1_k127_6878897_0 - - - - 0.000000000000000000000000000000000000000000000000006544 187.0
HFD1_k127_6878897_1 - - - - 0.0000000000000000000000000000000000000000000003076 177.0
HFD1_k127_6878897_2 Universal stress protein family - - - 0.0000000000005359 77.0
HFD1_k127_6892241_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.067e-238 747.0
HFD1_k127_6892241_1 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 381.0
HFD1_k127_6892241_10 TonB C terminal K03832 - - 0.0000000000000000005285 98.0
HFD1_k127_6892241_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 369.0
HFD1_k127_6892241_3 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 367.0
HFD1_k127_6892241_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 340.0
HFD1_k127_6892241_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 290.0
HFD1_k127_6892241_6 PP-loop family K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004703 262.0
HFD1_k127_6892241_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000003494 244.0
HFD1_k127_6892241_8 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.0000000000000000000000000000000000007685 146.0
HFD1_k127_6892241_9 Biopolymer transport protein K03560 - - 0.000000000000000000002217 98.0
HFD1_k127_6897313_0 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 593.0
HFD1_k127_6897313_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000006693 237.0
HFD1_k127_6897313_10 Tripartite tricarboxylate transporter family receptor - - - 0.00000002256 58.0
HFD1_k127_6897313_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000003859 217.0
HFD1_k127_6897313_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000001887 215.0
HFD1_k127_6897313_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000417 181.0
HFD1_k127_6897313_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000001868 183.0
HFD1_k127_6897313_6 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000003374 165.0
HFD1_k127_6897313_7 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000006323 155.0
HFD1_k127_6897313_8 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000002088 115.0
HFD1_k127_6897313_9 4Fe-4S binding domain - - - 0.000000000000000006066 86.0
HFD1_k127_6898897_0 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 306.0
HFD1_k127_6898897_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 296.0
HFD1_k127_6898897_2 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000000000007406 213.0
HFD1_k127_6898897_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.0000000003625 66.0
HFD1_k127_6900419_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 497.0
HFD1_k127_6900419_1 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 327.0
HFD1_k127_6900419_2 Fe-S-cluster-containing hydrogenase K08358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008444 259.0
HFD1_k127_6900419_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000001686 243.0
HFD1_k127_6900419_4 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000003119 213.0
HFD1_k127_6900419_5 prohibitin homologues - - - 0.00000000000001423 75.0
HFD1_k127_6905704_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.654e-291 910.0
HFD1_k127_6929987_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 553.0
HFD1_k127_6929987_1 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 303.0
HFD1_k127_6929987_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001847 255.0
HFD1_k127_6929987_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000006695 173.0
HFD1_k127_6929987_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000002779 154.0
HFD1_k127_6932995_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 477.0
HFD1_k127_6932995_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000008844 241.0
HFD1_k127_6932995_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000072 59.0
HFD1_k127_6952074_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.194e-196 631.0
HFD1_k127_6952074_1 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 455.0
HFD1_k127_6952074_2 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000006312 211.0
HFD1_k127_6952074_3 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000003209 196.0
HFD1_k127_6959740_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 535.0
HFD1_k127_6959740_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 503.0
HFD1_k127_6959740_2 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 476.0
HFD1_k127_6962624_0 Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome), yielding free amino acids K13722 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.643e-232 743.0
HFD1_k127_6966009_0 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 497.0
HFD1_k127_6966009_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 414.0
HFD1_k127_6966009_2 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 390.0
HFD1_k127_6966009_3 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 319.0
HFD1_k127_6966009_4 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 305.0
HFD1_k127_6966009_5 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000001352 102.0
HFD1_k127_705036_0 Alginate O-acetylation protein - - - 6.583e-198 627.0
HFD1_k127_705036_1 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 524.0
HFD1_k127_705036_10 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000001569 56.0
HFD1_k127_705036_2 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 308.0
HFD1_k127_705036_3 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003127 285.0
HFD1_k127_705036_4 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001051 273.0
HFD1_k127_705036_5 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000312 270.0
HFD1_k127_705036_6 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001364 263.0
HFD1_k127_705036_7 - - - - 0.0000000000000000000000000000000000004864 153.0
HFD1_k127_705036_8 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000000000002401 130.0
HFD1_k127_705036_9 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000002256 115.0
HFD1_k127_7054107_0 BadF BadG BcrA BcrD - - - 0.0 1540.0
HFD1_k127_7054107_1 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000001054 112.0
HFD1_k127_7054206_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.367e-206 649.0
HFD1_k127_7054206_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 305.0
HFD1_k127_7054206_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001285 182.0
HFD1_k127_7054206_3 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000005226 178.0
HFD1_k127_7054206_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000000008385 136.0
HFD1_k127_7054206_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000004601 81.0
HFD1_k127_7054206_6 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002401 73.0
HFD1_k127_7057644_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 2.86e-295 925.0
HFD1_k127_7057644_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 1.073e-200 641.0
HFD1_k127_7057644_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 505.0
HFD1_k127_7057644_3 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000216 229.0
HFD1_k127_7057644_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000001021 122.0
HFD1_k127_7064854_0 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 497.0
HFD1_k127_7064854_1 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 358.0
HFD1_k127_7074484_0 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01848 - 5.4.99.2 5.313e-240 754.0
HFD1_k127_7074484_1 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000003617 150.0
HFD1_k127_7074484_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000005674 59.0
HFD1_k127_7075979_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.745e-253 797.0
HFD1_k127_7075979_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 338.0
HFD1_k127_7075979_2 HTH domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 301.0
HFD1_k127_7075979_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000002807 236.0
HFD1_k127_7075979_4 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000002057 203.0
HFD1_k127_7075979_5 cellulase activity - - - 0.000001493 56.0
HFD1_k127_7083394_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 1.632e-233 744.0
HFD1_k127_7083394_1 CO dehydrogenase flavoprotein K03518,K13481 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 304.0
HFD1_k127_7083394_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009234 256.0
HFD1_k127_7083394_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000001361 226.0
HFD1_k127_7083394_4 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000003998 60.0
HFD1_k127_7112762_0 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 383.0
HFD1_k127_7112762_1 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000736 272.0
HFD1_k127_7112762_2 Single Cache domain 2 K02480 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002188 281.0
HFD1_k127_7112762_3 - - - - 0.00000000000000000001342 99.0
HFD1_k127_7112762_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000001651 66.0
HFD1_k127_7120613_0 alpha amylase catalytic K01182,K05343 - 3.2.1.1,3.2.1.10,5.4.99.16 0.0 1035.0
HFD1_k127_7120613_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 1.844e-261 825.0
HFD1_k127_7120613_2 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 501.0
HFD1_k127_7120613_3 Trehalose-phosphatase K16055 - 2.4.1.15,3.1.3.12 0.000000000000000000000000000000000000000000000119 178.0
HFD1_k127_7120613_4 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000001965 134.0
HFD1_k127_7122154_0 peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000711 282.0
HFD1_k127_7122154_1 - - - - 0.00000000000000000000000000000000000000003363 160.0
HFD1_k127_7122154_2 Single Cache domain 2 K03406 - - 0.00000000000002011 75.0
HFD1_k127_7122154_3 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.000000001102 68.0
HFD1_k127_7132764_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 585.0
HFD1_k127_7132764_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 - 2.1.3.3,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009091 361.0
HFD1_k127_7132764_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000003251 244.0
HFD1_k127_7132764_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000006059 220.0
HFD1_k127_7146302_0 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 425.0
HFD1_k127_7146302_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 400.0
HFD1_k127_7146302_2 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 379.0
HFD1_k127_7146302_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000001577 191.0
HFD1_k127_7146302_4 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000000000000001456 168.0
HFD1_k127_7146302_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000514 144.0
HFD1_k127_7146302_6 - - - - 0.00000000000000000000001059 106.0
HFD1_k127_7146302_7 Universal stress protein family - - - 0.000000000000000000003711 98.0
HFD1_k127_7146302_8 Mut7-C ubiquitin - - - 0.00000000000000003702 84.0
HFD1_k127_7157663_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 572.0
HFD1_k127_7157663_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 423.0
HFD1_k127_7157663_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000003301 223.0
HFD1_k127_7157663_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000005682 214.0
HFD1_k127_7157663_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000003244 174.0
HFD1_k127_7157663_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000001889 144.0
HFD1_k127_7157663_6 RNA polymerase-binding protein DksA K06204 - - 0.000000000000000000000001217 109.0
HFD1_k127_7158359_0 denitrification pathway - - - 9.837e-213 673.0
HFD1_k127_7158359_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 595.0
HFD1_k127_7158359_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 527.0
HFD1_k127_7158359_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004224 278.0
HFD1_k127_7158359_4 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000007205 254.0
HFD1_k127_7161697_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 479.0
HFD1_k127_7161697_1 PFAM Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 299.0
HFD1_k127_7161697_2 Beta-lactamase superfamily domain K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 301.0
HFD1_k127_7161697_3 ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005127 283.0
HFD1_k127_7161697_4 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000005257 218.0
HFD1_k127_7161697_5 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000003528 119.0
HFD1_k127_7161697_6 - - - - 0.0000000002407 64.0
HFD1_k127_7182229_0 Metallo-beta-lactamase domain protein K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 521.0
HFD1_k127_7182229_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 362.0
HFD1_k127_7182229_2 ThiJ PfpI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 310.0
HFD1_k127_7182229_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 302.0
HFD1_k127_7182229_4 LUD domain - - - 0.0000000000000000000000000000000000000000000000000000002764 200.0
HFD1_k127_7182229_5 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000001094 190.0
HFD1_k127_7182229_6 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000008289 123.0
HFD1_k127_7182229_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000008151 95.0
HFD1_k127_7182229_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000001774 74.0
HFD1_k127_7182229_9 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.000000001077 66.0
HFD1_k127_7199077_0 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 302.0
HFD1_k127_7199077_1 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 301.0
HFD1_k127_7199077_2 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000002488 196.0
HFD1_k127_7199077_4 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000001254 120.0
HFD1_k127_7209240_0 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001346 216.0
HFD1_k127_7209240_1 Von Willebrand factor type A domain K07114 - - 0.00000000000000812 85.0
HFD1_k127_7209240_2 PRC-barrel domain - - - 0.00000000001501 71.0
HFD1_k127_7209240_3 oxidoreductase activity K07114,K16257 - - 0.0000000133 66.0
HFD1_k127_7209240_4 - K16256 - - 0.00001302 55.0
HFD1_k127_7209240_5 UPF0391 membrane protein - - - 0.0001018 47.0
HFD1_k127_72334_0 hmm pf01266 K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 404.0
HFD1_k127_72334_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000005701 205.0
HFD1_k127_72334_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000001721 138.0
HFD1_k127_7238812_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K03387 - - 0.000000000000000000000000000000000000000000000000000000000000000000002858 248.0
HFD1_k127_7238812_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000003371 155.0
HFD1_k127_7238812_2 MmgE PrpD family protein K01720 - 4.2.1.79 0.000000000000000000000000000000001141 133.0
HFD1_k127_7238812_3 nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.000000000000000000000002434 109.0
HFD1_k127_7238812_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000004266 70.0
HFD1_k127_7238812_5 SNARE associated Golgi protein - - - 0.0000000008884 59.0
HFD1_k127_7238938_0 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 419.0
HFD1_k127_7238938_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000000000000002334 226.0
HFD1_k127_7238938_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000001121 98.0
HFD1_k127_7238938_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000001691 51.0
HFD1_k127_7238938_4 peptidyl-tyrosine sulfation - - - 0.000005451 59.0
HFD1_k127_7238938_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00006599 56.0
HFD1_k127_7240000_0 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 345.0
HFD1_k127_7240000_1 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000466 200.0
HFD1_k127_7240000_2 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000008951 130.0
HFD1_k127_7240000_3 B3/4 domain - - - 0.0000000000000001602 88.0
HFD1_k127_72463_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 589.0
HFD1_k127_72463_1 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 340.0
HFD1_k127_72463_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006446 263.0
HFD1_k127_72463_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000002656 221.0
HFD1_k127_72463_4 Polymer-forming cytoskeletal - - - 0.00000000000000000007318 94.0
HFD1_k127_72463_5 - - - - 0.00000000000000041 83.0
HFD1_k127_72463_6 Tetratricopeptide repeat - - - 0.0009594 44.0
HFD1_k127_7251128_0 Responsible for energy coupling to the transport system K16784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 325.0
HFD1_k127_7251128_1 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000004456 235.0
HFD1_k127_7251128_2 BioY family K03523 - - 0.000000000000000000000000000000000000000000000000000000003492 204.0
HFD1_k127_7251128_3 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16783,K16785 - - 0.0000000000000000000000000007499 123.0
HFD1_k127_7251128_4 cheY-homologous receiver domain - - - 0.0000000000000000001092 94.0
HFD1_k127_7251128_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.0000000004385 67.0
HFD1_k127_7251128_6 - - - - 0.000000009679 57.0
HFD1_k127_7251128_7 Protein conserved in bacteria - - - 0.00000005311 56.0
HFD1_k127_7251128_8 Amidohydrolase - - - 0.000001576 59.0
HFD1_k127_7255409_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 530.0
HFD1_k127_7255409_1 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000002156 213.0
HFD1_k127_7255409_2 KaiB K08481 - - 0.0000000000000000000000000001537 119.0
HFD1_k127_7255409_3 PAS domain K03406 - - 0.000000000000000007384 90.0
HFD1_k127_7278836_0 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 315.0
HFD1_k127_7278836_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006961 276.0
HFD1_k127_7278836_2 FCD - - - 0.000000000000000000000000000000000000000000000000000003885 199.0
HFD1_k127_7278836_3 - - - - 0.000000000000000000000000000000000000000000000006987 173.0
HFD1_k127_7278836_4 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01069 - 3.1.2.6 0.00000000000000000000000000000000000000007884 158.0
HFD1_k127_7320_0 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007933 255.0
HFD1_k127_7320_1 - - - - 0.00000000000000000001275 92.0
HFD1_k127_732922_0 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 334.0
HFD1_k127_732922_1 NAD(P)-binding Rossmann-like domain K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000001402 255.0
HFD1_k127_7352457_0 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 477.0
HFD1_k127_7352457_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003016 243.0
HFD1_k127_7352457_2 Peptidase_C39 like family - - - 0.000000000000000000000000000001107 127.0
HFD1_k127_7355133_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007562 267.0
HFD1_k127_7355133_1 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000007795 199.0
HFD1_k127_7355133_2 - - - - 0.000000000000000000001097 99.0
HFD1_k127_7355133_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000001311 83.0
HFD1_k127_7355133_4 YtkA-like - - - 0.0003502 49.0
HFD1_k127_7355133_5 - - - - 0.0003655 51.0
HFD1_k127_7391438_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 317.0
HFD1_k127_7391438_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000001773 222.0
HFD1_k127_7391438_10 nuclease - - - 0.0002948 54.0
HFD1_k127_7391438_2 ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000001033 229.0
HFD1_k127_7391438_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000008289 91.0
HFD1_k127_7391438_4 LETM1-like protein - - - 0.000000005398 60.0
HFD1_k127_7391438_5 formylmethanofuran dehydrogenase subunit C K00202 - 1.2.7.12 0.00000006797 63.0
HFD1_k127_7391438_6 Domain of unknown function (DUF4124) - - - 0.0000001087 60.0
HFD1_k127_7391438_7 Curli production assembly/transport component CsgG - - - 0.0000048 58.0
HFD1_k127_7391438_8 - - - - 0.0000151 51.0
HFD1_k127_7403200_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 382.0
HFD1_k127_7403200_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001987 261.0
HFD1_k127_7403200_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000009827 213.0
HFD1_k127_7403200_3 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000002334 208.0
HFD1_k127_7403200_4 PFAM FecR protein - - - 0.000000000000000000000000000000000000000007669 166.0
HFD1_k127_7403838_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.793e-321 990.0
HFD1_k127_7409272_0 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 406.0
HFD1_k127_7409272_1 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 351.0
HFD1_k127_7409272_2 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 307.0
HFD1_k127_7419553_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 458.0
HFD1_k127_7419553_1 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000009353 251.0
HFD1_k127_7419553_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000005581 154.0
HFD1_k127_7419553_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000001147 67.0
HFD1_k127_7444339_0 Enoyl-CoA hydratase/isomerase K07539 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 1.621e-210 657.0
HFD1_k127_7444339_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 368.0
HFD1_k127_7444339_2 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 274.0
HFD1_k127_7444339_3 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000377 233.0
HFD1_k127_7444339_4 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000566 104.0
HFD1_k127_7444339_5 ThiS family K03636 - - 0.00000002863 58.0
HFD1_k127_7444339_6 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000001283 53.0
HFD1_k127_7450317_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 554.0
HFD1_k127_7450317_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 531.0
HFD1_k127_7450317_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 379.0
HFD1_k127_7450317_3 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 295.0
HFD1_k127_7450317_4 pfam nlp p60 - - - 0.00000000000000000000000000000000000000000000000000000000001834 223.0
HFD1_k127_7450317_5 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000000003605 178.0
HFD1_k127_7450317_6 - - - - 0.00000000000000000000000000002035 119.0
HFD1_k127_7450317_7 lysyltransferase activity K07027 - - 0.00000000000000000000000003108 119.0
HFD1_k127_7463623_0 Rhs element vgr protein - - - 0.00000000000000000000000000000000001574 140.0
HFD1_k127_7463623_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000001358 132.0
HFD1_k127_7463623_2 - - - - 0.00000000002629 70.0
HFD1_k127_7481829_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 591.0
HFD1_k127_7481829_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 402.0
HFD1_k127_7481829_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002233 274.0
HFD1_k127_7481829_3 - - - - 0.0004414 48.0
HFD1_k127_7496703_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 9.087e-207 653.0
HFD1_k127_7496703_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000009883 203.0
HFD1_k127_7496703_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000003221 116.0
HFD1_k127_7517882_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 563.0
HFD1_k127_7517882_1 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 266.0
HFD1_k127_7517882_2 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000004071 189.0
HFD1_k127_7517882_3 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000001259 160.0
HFD1_k127_7517882_4 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000000000000000000222 133.0
HFD1_k127_7517882_5 PFAM Rubrerythrin - - - 0.000000000000000000000001217 109.0
HFD1_k127_7517882_6 thioesterase - - - 0.000000000000000000000002671 107.0
HFD1_k127_7517882_7 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate - - - 0.0000000000008578 71.0
HFD1_k127_7517882_8 Sporulation protein YtfJ - - - 0.000000000009996 70.0
HFD1_k127_7528870_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 363.0
HFD1_k127_7528870_1 ABC transporter K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002348 263.0
HFD1_k127_7528870_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008941 254.0
HFD1_k127_7528870_3 ABC transporter, ATP-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000005504 206.0
HFD1_k127_7528870_4 lipoprotein transporter activity K02003,K02065,K06857,K09810,K09812 - 3.6.3.55 0.00000000000000000000000000000000000000005927 159.0
HFD1_k127_7528870_5 lipoprotein transporter activity K02003,K02065,K06857,K09810,K09812 - 3.6.3.55 0.000000000000000000000000001283 121.0
HFD1_k127_7528870_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000002656 82.0
HFD1_k127_7528870_8 ABC transporter, permease protein K02004 - - 0.000000000000991 80.0
HFD1_k127_7545989_0 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000002822 85.0
HFD1_k127_7557354_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 549.0
HFD1_k127_7557354_1 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 304.0
HFD1_k127_7557354_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 302.0
HFD1_k127_7557354_3 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.00000000000000000000000000000000000000000002378 165.0
HFD1_k127_757264_0 cell wall hydrolase K01449 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000003466 250.0
HFD1_k127_757264_1 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000009139 133.0
HFD1_k127_757264_2 Trypsin - - - 0.000000000000000000000002302 113.0
HFD1_k127_757264_3 Protein of unknown function (DUF2950) - - - 0.00000000000000003433 86.0
HFD1_k127_757264_4 PFAM NADPH-dependent FMN reductase K19784 - - 0.00000001045 59.0
HFD1_k127_7578331_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 397.0
HFD1_k127_7578331_1 BadF BadG BcrA BcrD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 388.0
HFD1_k127_7578331_10 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000001052 112.0
HFD1_k127_7578331_11 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000001912 97.0
HFD1_k127_7578331_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 357.0
HFD1_k127_7578331_3 B12 binding domain K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 330.0
HFD1_k127_7578331_4 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000001258 278.0
HFD1_k127_7578331_5 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001648 277.0
HFD1_k127_7578331_6 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000001947 226.0
HFD1_k127_7578331_7 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000006193 210.0
HFD1_k127_7578331_8 [acyl-carrier-protein] S-malonyltransferase activity - - - 0.0000000000000000000000000000000002322 144.0
HFD1_k127_7578331_9 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000003743 136.0
HFD1_k127_7578971_0 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 494.0
HFD1_k127_7578971_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 486.0
HFD1_k127_7578971_2 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 409.0
HFD1_k127_7578971_3 binding domain protein - - - 0.00000000000000000000000000000000005482 144.0
HFD1_k127_7578971_4 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000005588 116.0
HFD1_k127_7578971_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000001686 99.0
HFD1_k127_7629822_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 459.0
HFD1_k127_7629822_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 362.0
HFD1_k127_7629822_2 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001282 210.0
HFD1_k127_7629822_3 xanthine dehydrogenase activity K03519,K13479,K20445 - 1.17.1.4,1.17.1.5,1.2.5.3 0.000000000000000000000000000000000000000000000000000000101 205.0
HFD1_k127_7655852_0 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 305.0
HFD1_k127_7655852_1 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002564 256.0
HFD1_k127_7655852_2 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000001297 189.0
HFD1_k127_7655852_3 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000001588 76.0
HFD1_k127_7707111_0 Large extracellular alpha-helical protein K06894 - - 0.0 1950.0
HFD1_k127_7707384_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 5.267e-209 659.0
HFD1_k127_7707384_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 346.0
HFD1_k127_7707384_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 329.0
HFD1_k127_7707384_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000008401 261.0
HFD1_k127_7707384_4 D-arabinono-1,4-lactone oxidase K16653 - 1.1.98.3 0.0000000000000000000000000000001042 125.0
HFD1_k127_7707384_5 PFAM Transposase IS200 like - - - 0.00000000000001853 73.0
HFD1_k127_7714089_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 623.0
HFD1_k127_7714089_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 291.0
HFD1_k127_7714089_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000008595 85.0
HFD1_k127_7734343_0 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 318.0
HFD1_k127_7734343_1 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 318.0
HFD1_k127_7734343_2 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000264 286.0
HFD1_k127_7734343_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004337 281.0
HFD1_k127_7734343_4 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002377 271.0
HFD1_k127_7734343_5 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002588 266.0
HFD1_k127_7734343_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000007918 230.0
HFD1_k127_7734343_7 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000001205 227.0
HFD1_k127_7734343_8 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000001277 140.0
HFD1_k127_7737202_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.63e-254 798.0
HFD1_k127_7737202_1 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 1.16e-220 690.0
HFD1_k127_7737202_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 492.0
HFD1_k127_7737202_3 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000001486 175.0
HFD1_k127_7737202_4 Lipocalin-like domain - - - 0.00000000000000000000000000000000000003078 149.0
HFD1_k127_7737202_5 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000292 142.0
HFD1_k127_7737202_6 hydrolase - - - 0.000000000000000001072 98.0
HFD1_k127_7737202_7 DEAD/H associated K03724 - - 0.00000000004698 65.0
HFD1_k127_7757099_0 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 348.0
HFD1_k127_7757099_1 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 304.0
HFD1_k127_7764224_0 SMART ATPase, AAA type, core K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 565.0
HFD1_k127_7764224_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000003387 194.0
HFD1_k127_7764224_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000004096 177.0
HFD1_k127_7764224_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000001993 165.0
HFD1_k127_7764224_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000000000001222 113.0
HFD1_k127_776776_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 541.0
HFD1_k127_776776_1 ABC transporter K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 316.0
HFD1_k127_776776_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 291.0
HFD1_k127_776776_3 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004917 281.0
HFD1_k127_776776_4 Conserved carboxylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001276 242.0
HFD1_k127_776776_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000006653 117.0
HFD1_k127_7770733_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.184e-258 807.0
HFD1_k127_7770733_1 PFAM Enoyl-CoA hydratase isomerase - - - 5.566e-221 705.0
HFD1_k127_7770733_2 PFAM AMP-dependent synthetase and ligase K00666,K01897,K12508 - 6.2.1.3,6.2.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 450.0
HFD1_k127_7770733_3 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000002985 256.0
HFD1_k127_7770733_4 GntR family - - - 0.0000000000000000000000000000000000000000000000000000003604 201.0
HFD1_k127_7770733_5 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000006321 187.0
HFD1_k127_7770733_6 Major Facilitator - - - 0.000000000000000000000000000000000000000000000002303 189.0
HFD1_k127_7770733_7 Protein of unknown function (DUF434) - - - 0.00000000004804 68.0
HFD1_k127_7790298_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1622.0
HFD1_k127_7790298_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000001337 171.0
HFD1_k127_7790298_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 0.00000000000000007243 94.0
HFD1_k127_7794036_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 610.0
HFD1_k127_7794036_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 540.0
HFD1_k127_7794036_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 449.0
HFD1_k127_7794036_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 378.0
HFD1_k127_7794036_4 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 301.0
HFD1_k127_7794036_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 295.0
HFD1_k127_7794036_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000001236 265.0
HFD1_k127_7794036_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000005303 134.0
HFD1_k127_7794036_8 PFAM Major Facilitator Superfamily K08153,K19576 - - 0.00005509 55.0
HFD1_k127_7797271_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.829e-200 635.0
HFD1_k127_7797271_1 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 304.0
HFD1_k127_7797271_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000001803 229.0
HFD1_k127_7797271_3 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000003628 213.0
HFD1_k127_7797271_4 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087 - 1.17.1.4 0.0000000000000000000000000000000000000004994 161.0
HFD1_k127_7797271_5 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000002872 64.0
HFD1_k127_7797271_6 - - - - 0.0002033 46.0
HFD1_k127_7807846_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 559.0
HFD1_k127_7807846_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 542.0
HFD1_k127_7807846_2 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 473.0
HFD1_k127_7807846_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 355.0
HFD1_k127_7807846_4 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000362 262.0
HFD1_k127_7807846_5 Membrane - - - 0.000000000000000000000000000000000000000000000000000001105 205.0
HFD1_k127_7807846_6 Helix-hairpin-helix motif - - - 0.0000000000000000000000000000000000001101 150.0
HFD1_k127_7807846_7 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000005802 143.0
HFD1_k127_7807846_8 - - - - 0.0000000000000000000000566 101.0
HFD1_k127_780845_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.462e-243 764.0
HFD1_k127_780845_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 431.0
HFD1_k127_780845_2 PRC-barrel domain - - - 0.000000000000000000001968 102.0
HFD1_k127_780845_3 YtxH-like protein - - - 0.0000000000000007041 80.0
HFD1_k127_780845_5 PFAM PRC-barrel domain protein - - - 0.0001422 45.0
HFD1_k127_7816319_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 471.0
HFD1_k127_7816319_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 396.0
HFD1_k127_7816319_2 PFAM ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 335.0
HFD1_k127_7816319_3 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 325.0
HFD1_k127_7816319_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000002641 81.0
HFD1_k127_7853724_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0 1094.0
HFD1_k127_7853724_1 COG1228 Imidazolonepropionase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 532.0
HFD1_k127_7853724_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 397.0
HFD1_k127_7853724_3 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 388.0
HFD1_k127_7853724_4 - - - - 0.00000000000000000000000000000000000000000000000000009169 208.0
HFD1_k127_7853724_5 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000002684 73.0
HFD1_k127_7855324_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000076 243.0
HFD1_k127_7855324_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000001209 211.0
HFD1_k127_7855324_2 Glycosyl transferase, family 2 K00721,K01912,K08301 - 2.4.1.83,6.2.1.30 0.0000000000000000000000000000000000000000000000000001634 194.0
HFD1_k127_7855324_3 lysyltransferase activity K07027,K20468 - - 0.0000000000000000000000000000000007647 143.0
HFD1_k127_7855324_4 COG0500 SAM-dependent methyltransferases - - - 0.00000001924 64.0
HFD1_k127_7855324_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00009207 55.0
HFD1_k127_7869057_0 Aldehyde dehydrogenase family K22187 - - 1.254e-208 659.0
HFD1_k127_7869057_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 418.0
HFD1_k127_7869057_2 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 396.0
HFD1_k127_7869057_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000001281 87.0
HFD1_k127_788076_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 599.0
HFD1_k127_788076_1 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 573.0
HFD1_k127_788076_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 374.0
HFD1_k127_788076_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 366.0
HFD1_k127_788076_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 300.0
HFD1_k127_788076_5 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000174 127.0
HFD1_k127_788076_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000002303 109.0
HFD1_k127_788076_7 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000002547 94.0
HFD1_k127_788076_8 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.00004851 46.0
HFD1_k127_7894279_0 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 397.0
HFD1_k127_7894279_1 ECF sigma factor - - - 0.0000000000000001611 83.0
HFD1_k127_7894279_2 - - - - 0.0000000000004785 76.0
HFD1_k127_7894279_3 Putative zinc-finger - - - 0.0004458 49.0
HFD1_k127_7895077_0 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 395.0
HFD1_k127_7895077_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 366.0
HFD1_k127_7895077_2 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 317.0
HFD1_k127_7895077_3 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006103 254.0
HFD1_k127_7895077_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001624 219.0
HFD1_k127_7895077_5 Protein of unknown function (DUF1571) - - - 0.00000000000000000000000000000000000001479 153.0
HFD1_k127_7895077_6 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000222 144.0
HFD1_k127_7895077_7 - - - - 0.000000003855 66.0
HFD1_k127_7903364_0 ACT domain K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 339.0
HFD1_k127_7903364_1 PFAM Bile acid sodium symporter K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000002409 231.0
HFD1_k127_7903364_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000002321 219.0
HFD1_k127_7903364_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000001443 152.0
HFD1_k127_7907945_0 Endoribonuclease that initiates mRNA decay K18682 - - 2.661e-215 680.0
HFD1_k127_7907945_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 420.0
HFD1_k127_7907945_2 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 299.0
HFD1_k127_7907945_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000002458 59.0
HFD1_k127_7956546_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 553.0
HFD1_k127_7956546_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001773 289.0
HFD1_k127_7956546_2 Universal stress protein - - - 0.000000000000000000000006729 107.0
HFD1_k127_797167_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.295e-227 717.0
HFD1_k127_797167_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 395.0
HFD1_k127_797167_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 364.0
HFD1_k127_797167_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 337.0
HFD1_k127_797167_4 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 334.0
HFD1_k127_7983431_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 593.0
HFD1_k127_7983431_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 556.0
HFD1_k127_7983431_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000002497 180.0
HFD1_k127_7983431_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000000000002069 155.0
HFD1_k127_83063_0 carbon starvation protein CstA K06200 - - 1.914e-265 826.0
HFD1_k127_83063_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 576.0
HFD1_k127_83063_10 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000003356 53.0
HFD1_k127_83063_2 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 308.0
HFD1_k127_83063_3 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001225 281.0
HFD1_k127_83063_4 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000000486 191.0
HFD1_k127_83063_5 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000249 181.0
HFD1_k127_83063_6 - - - - 0.0000000000000000000000000000000000000000006535 158.0
HFD1_k127_83063_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000002005 154.0
HFD1_k127_83063_8 - - - - 0.0000000008166 61.0
HFD1_k127_83063_9 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000001465 53.0
HFD1_k127_839234_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 316.0
HFD1_k127_839234_1 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000001784 233.0
HFD1_k127_856387_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 462.0
HFD1_k127_856387_1 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 355.0
HFD1_k127_856387_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
HFD1_k127_856387_3 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000003585 233.0
HFD1_k127_856387_4 Pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.000000000000000000000000000000000000004098 147.0
HFD1_k127_856387_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000007644 145.0
HFD1_k127_865103_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.327e-218 687.0
HFD1_k127_865103_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.102e-200 632.0
HFD1_k127_865103_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 305.0
HFD1_k127_865103_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000003624 251.0
HFD1_k127_865103_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000006998 228.0
HFD1_k127_865103_5 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000001371 151.0
HFD1_k127_865103_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000001509 108.0
HFD1_k127_867539_0 Belongs to the glycosyl hydrolase 57 family K06044 - 5.4.99.15 4.4e-323 1006.0
HFD1_k127_867539_1 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 512.0
HFD1_k127_867539_2 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.00000000000000000000000000000000000000000000001535 173.0
HFD1_k127_874655_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 305.0
HFD1_k127_874655_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001722 282.0
HFD1_k127_874655_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001283 226.0
HFD1_k127_874655_3 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000003605 149.0
HFD1_k127_874655_4 Belongs to the Fur family K03711 - - 0.000000000000000000001054 99.0
HFD1_k127_874655_5 Cobalt transport protein K02008 - - 0.00002453 55.0
HFD1_k127_874655_6 Ribosomal protein L11 methyltransferase K02687 - - 0.00008977 49.0
HFD1_k127_892116_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 606.0
HFD1_k127_892116_1 acetyltransferase K19113 - - 0.00000000000000000000000000000000000000000000000000000000000000000005171 239.0
HFD1_k127_892116_2 Domain of unknown function (DUF4833) - - - 0.000000000000002812 83.0
HFD1_k127_895034_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K00355,K05587,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 8.955e-290 899.0
HFD1_k127_895034_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 587.0
HFD1_k127_895034_10 Transcription regulator MerR DNA binding K21902 - - 0.000000000000000000000000000000000000000006581 158.0
HFD1_k127_895034_11 Ferredoxin K17992 - 1.12.1.3 0.00000000000000000000000000000000000000001156 156.0
HFD1_k127_895034_12 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000004158 150.0
HFD1_k127_895034_13 DRTGG domain - - - 0.00000000000000000000000000002033 121.0
HFD1_k127_895034_14 DRTGG domain protein - - - 0.0000000000000000000000000001935 118.0
HFD1_k127_895034_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 474.0
HFD1_k127_895034_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 444.0
HFD1_k127_895034_4 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 418.0
HFD1_k127_895034_5 lactate metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 404.0
HFD1_k127_895034_6 PFAM PHP domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000227 211.0
HFD1_k127_895034_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000003709 197.0
HFD1_k127_895034_8 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000000000000000000000000007291 179.0
HFD1_k127_895034_9 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000009828 178.0
HFD1_k127_901787_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 392.0
HFD1_k127_901787_1 GAF domain - - - 0.000000000000000000000000000000000000000000000000000008768 205.0
HFD1_k127_901787_2 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000001818 120.0
HFD1_k127_915947_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.206e-224 710.0
HFD1_k127_915947_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000002657 179.0
HFD1_k127_915947_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000006734 107.0
HFD1_k127_915947_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000983 62.0
HFD1_k127_922117_0 Molybdate transporter of MFS superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 602.0
HFD1_k127_922117_1 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 601.0
HFD1_k127_922117_10 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000003626 189.0
HFD1_k127_922117_11 DGC domain - - - 0.0000000000000000000000000000000000000000000000002022 179.0
HFD1_k127_922117_12 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.00000000000000000000000000000000005552 138.0
HFD1_k127_922117_13 Putative Fe-S cluster - - - 0.000000000000000000000000000000002143 136.0
HFD1_k127_922117_14 Putative Fe-S cluster - - - 0.00000000000000000000000000006326 122.0
HFD1_k127_922117_15 Periplasmic binding protein K01999 - - 0.0000000000000000000000000003095 128.0
HFD1_k127_922117_16 Thioredoxin domain - - - 0.0000000000000000000000000004516 119.0
HFD1_k127_922117_17 TIGRFAM redox-active disulfide protein 2 - - - 0.00000000000000000000005004 100.0
HFD1_k127_922117_18 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000006605 99.0
HFD1_k127_922117_19 Thioredoxin K03671 - - 0.000000000000000000003175 98.0
HFD1_k127_922117_2 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 481.0
HFD1_k127_922117_20 - - - - 0.000000000000004511 78.0
HFD1_k127_922117_21 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000009107 64.0
HFD1_k127_922117_23 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000006504 51.0
HFD1_k127_922117_3 ABC transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000132 276.0
HFD1_k127_922117_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003875 273.0
HFD1_k127_922117_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006661 266.0
HFD1_k127_922117_6 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006571 238.0
HFD1_k127_922117_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000005044 191.0
HFD1_k127_922117_8 DGC domain - - - 0.0000000000000000000000000000000000000000000000000002141 188.0
HFD1_k127_922117_9 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000001071 192.0
HFD1_k127_926899_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 464.0
HFD1_k127_926899_1 quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 369.0
HFD1_k127_926899_2 - - - - 0.0000000000000000000000001152 111.0
HFD1_k127_948877_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 421.0
HFD1_k127_948877_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 306.0
HFD1_k127_948877_2 Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) K11416 GO:0000003,GO:0000018,GO:0000166,GO:0000228,GO:0000578,GO:0000781,GO:0000784,GO:0000785,GO:0000790,GO:0000792,GO:0001672,GO:0001936,GO:0001938,GO:0003002,GO:0003006,GO:0003007,GO:0003241,GO:0003245,GO:0003247,GO:0003674,GO:0003682,GO:0003712,GO:0003714,GO:0003824,GO:0003950,GO:0003956,GO:0004407,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005694,GO:0005720,GO:0005724,GO:0005737,GO:0006109,GO:0006110,GO:0006139,GO:0006140,GO:0006259,GO:0006281,GO:0006282,GO:0006284,GO:0006325,GO:0006355,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007314,GO:0007315,GO:0007350,GO:0007351,GO:0007389,GO:0007507,GO:0007517,GO:0007568,GO:0008134,GO:0008150,GO:0008152,GO:0008270,GO:0008284,GO:0008285,GO:0008340,GO:0008358,GO:0008595,GO:0009266,GO:0009408,GO:0009628,GO:0009653,GO:0009790,GO:0009798,GO:0009880,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009948,GO:0009952,GO:0009987,GO:0009994,GO:0010259,GO:0010468,GO:0010494,GO:0010556,GO:0010558,GO:0010563,GO:0010569,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0010675,GO:0010677,GO:0010827,GO:0010829,GO:0010847,GO:0012505,GO:0014706,GO:0016043,GO:0016049,GO:0016569,GO:0016570,GO:0016575,GO:0016740,GO:0016757,GO:0016763,GO:0016787,GO:0016810,GO:0016811,GO:0017136,GO:0019213,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019953,GO:0021700,GO:0022412,GO:0022414,GO:0022603,GO:0022607,GO:0022613,GO:0022618,GO:0030154,GO:0030719,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0031445,GO:0031453,GO:0031647,GO:0031648,GO:0031933,GO:0031935,GO:0031937,GO:0031938,GO:0031940,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032129,GO:0032204,GO:0032206,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032991,GO:0033043,GO:0033044,GO:0033500,GO:0033554,GO:0033558,GO:0034622,GO:0034641,GO:0034762,GO:0034763,GO:0034979,GO:0035265,GO:0035282,GO:0035601,GO:0035770,GO:0036094,GO:0036211,GO:0036464,GO:0040007,GO:0042127,GO:0042325,GO:0042326,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043186,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043467,GO:0043470,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0045495,GO:0045765,GO:0045766,GO:0045799,GO:0045820,GO:0045892,GO:0045912,GO:0045934,GO:0045935,GO:0045936,GO:0045980,GO:0046324,GO:0046325,GO:0046483,GO:0046872,GO:0046914,GO:0046969,GO:0048037,GO:0048145,GO:0048146,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048588,GO:0048589,GO:0048599,GO:0048609,GO:0048644,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050678,GO:0050679,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051052,GO:0051054,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051276,GO:0051287,GO:0051704,GO:0051716,GO:0055008,GO:0055017,GO:0060255,GO:0060293,GO:0060415,GO:0060419,GO:0060537,GO:0060560,GO:0060688,GO:0060968,GO:0061061,GO:0061647,GO:0062012,GO:0062014,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070403,GO:0070925,GO:0070932,GO:0071704,GO:0071826,GO:0071840,GO:0072091,GO:0072359,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0098687,GO:0098732,GO:0140096,GO:0140110,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901265,GO:1901342,GO:1901360,GO:1901363,GO:1901564,GO:1902275,GO:1902679,GO:1902732,GO:1903506,GO:1903507,GO:1903578,GO:1903579,GO:1903863,GO:1904018,GO:1905269,GO:1905330,GO:1905332,GO:1905547,GO:1905549,GO:1905553,GO:1905555,GO:1905562,GO:1905564,GO:1990619,GO:1990904,GO:2000026,GO:2000112,GO:2000113,GO:2000648,GO:2000779,GO:2001020,GO:2001141,GO:2001169,GO:2001170,GO:2001252 2.4.2.31 0.0000000000000000000000000000000000000000000000000000007188 199.0
HFD1_k127_948877_3 Na -dependent transporter K03453 - - 0.000000000000000000000000004163 122.0
HFD1_k127_948877_4 - - - - 0.000000000000000001165 86.0
HFD1_k127_948877_5 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000001126 84.0
HFD1_k127_973113_0 PFAM MltA K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 360.0
HFD1_k127_973113_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000002298 94.0
HFD1_k127_975301_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 612.0
HFD1_k127_975301_1 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 299.0