Overview

ID MAG01615
Name HFD1_bin.22
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class UBA9217
Order UBA9217
Family UBA9217
Genus JAAXXJ01
Species
Assembly information
Completeness (%) 78.0
Contamination (%) 4.22
GC content (%) 56.0
N50 (bp) 75,688
Genome size (bp) 2,340,333

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2089

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_127423_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.513e-240 757.0
HFD1_k127_127423_1 DNA topoisomerase II activity K02469,K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 3.127e-226 724.0
HFD1_k127_127423_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000003776 247.0
HFD1_k127_127423_11 CheR methyltransferase, SAM binding domain K21786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008224 248.0
HFD1_k127_127423_12 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000003195 231.0
HFD1_k127_127423_13 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000009992 221.0
HFD1_k127_127423_14 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000003478 150.0
HFD1_k127_127423_15 regulation of translation K03530 - - 0.000000000000000000000000000000000002828 141.0
HFD1_k127_127423_16 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000001483 139.0
HFD1_k127_127423_17 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000001161 134.0
HFD1_k127_127423_18 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000000000000004298 128.0
HFD1_k127_127423_19 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000001221 111.0
HFD1_k127_127423_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 382.0
HFD1_k127_127423_20 - - - - 0.000006764 51.0
HFD1_k127_127423_21 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0003404 52.0
HFD1_k127_127423_22 Universal stress protein - - - 0.0006156 49.0
HFD1_k127_127423_23 Psort location Cytoplasmic, score 8.96 - - - 0.0008761 50.0
HFD1_k127_127423_3 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 366.0
HFD1_k127_127423_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 350.0
HFD1_k127_127423_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 321.0
HFD1_k127_127423_6 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 297.0
HFD1_k127_127423_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002858 264.0
HFD1_k127_127423_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009387 263.0
HFD1_k127_127423_9 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000009168 254.0
HFD1_k127_1327537_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 425.0
HFD1_k127_1327537_1 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000607 280.0
HFD1_k127_1327537_2 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008377 271.0
HFD1_k127_1327537_3 - - - - 0.0000000000000000004801 87.0
HFD1_k127_14336_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000008893 242.0
HFD1_k127_14336_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000006287 225.0
HFD1_k127_14336_2 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000002531 229.0
HFD1_k127_14336_3 PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002028 220.0
HFD1_k127_14336_4 AAA domain - - - 0.00000000001521 78.0
HFD1_k127_1621703_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 593.0
HFD1_k127_1621703_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 466.0
HFD1_k127_1621703_10 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006871 267.0
HFD1_k127_1621703_11 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001658 258.0
HFD1_k127_1621703_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000003673 225.0
HFD1_k127_1621703_13 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000006689 215.0
HFD1_k127_1621703_14 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000002137 217.0
HFD1_k127_1621703_15 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000003374 208.0
HFD1_k127_1621703_16 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006014 200.0
HFD1_k127_1621703_17 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001737 198.0
HFD1_k127_1621703_18 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000008739 201.0
HFD1_k127_1621703_19 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000007587 198.0
HFD1_k127_1621703_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 447.0
HFD1_k127_1621703_20 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000000000000000000000000000001127 212.0
HFD1_k127_1621703_21 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000008685 193.0
HFD1_k127_1621703_22 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000000005003 193.0
HFD1_k127_1621703_23 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000001767 200.0
HFD1_k127_1621703_24 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000006821 186.0
HFD1_k127_1621703_25 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000008593 180.0
HFD1_k127_1621703_26 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001282 178.0
HFD1_k127_1621703_27 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000002708 168.0
HFD1_k127_1621703_28 Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000000000000000000005215 162.0
HFD1_k127_1621703_29 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000004888 153.0
HFD1_k127_1621703_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 405.0
HFD1_k127_1621703_30 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000001585 141.0
HFD1_k127_1621703_31 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000005576 142.0
HFD1_k127_1621703_32 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000001497 143.0
HFD1_k127_1621703_33 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000001504 129.0
HFD1_k127_1621703_34 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000197 123.0
HFD1_k127_1621703_35 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000001672 116.0
HFD1_k127_1621703_36 Transcriptional regulator, MerR family - - - 0.0000000000000000000000000007303 117.0
HFD1_k127_1621703_37 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000215 115.0
HFD1_k127_1621703_39 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000008336 107.0
HFD1_k127_1621703_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 392.0
HFD1_k127_1621703_40 integral membrane protein - - - 0.000000000000000315 88.0
HFD1_k127_1621703_41 Ribosomal protein L30 K02907 - - 0.000000000000003992 76.0
HFD1_k127_1621703_42 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000006082 74.0
HFD1_k127_1621703_43 Ribosomal L29 protein K02904 - - 0.00000000000003301 74.0
HFD1_k127_1621703_44 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000003251 68.0
HFD1_k127_1621703_45 HD domain K07814 - - 0.000002326 51.0
HFD1_k127_1621703_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 337.0
HFD1_k127_1621703_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 330.0
HFD1_k127_1621703_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 323.0
HFD1_k127_1621703_8 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 320.0
HFD1_k127_1621703_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 304.0
HFD1_k127_1678979_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 4.405e-313 983.0
HFD1_k127_1678979_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 329.0
HFD1_k127_1678979_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 312.0
HFD1_k127_1678979_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000007961 239.0
HFD1_k127_1678979_4 - - - - 0.00000000000001438 79.0
HFD1_k127_1715900_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 558.0
HFD1_k127_1715900_1 SMART Nucleotide binding protein PINc K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 458.0
HFD1_k127_1715900_2 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000002799 214.0
HFD1_k127_1715900_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000009727 201.0
HFD1_k127_1715900_4 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000004629 173.0
HFD1_k127_1715900_5 tRNA processing K06864 - - 0.000000000000000000002525 96.0
HFD1_k127_1723210_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1103.0
HFD1_k127_1723210_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1100.0
HFD1_k127_1723210_10 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 432.0
HFD1_k127_1723210_11 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 428.0
HFD1_k127_1723210_12 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 428.0
HFD1_k127_1723210_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 418.0
HFD1_k127_1723210_14 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 360.0
HFD1_k127_1723210_15 TIGRFAM transposase, IS605 OrfB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 360.0
HFD1_k127_1723210_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 376.0
HFD1_k127_1723210_17 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 333.0
HFD1_k127_1723210_18 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 316.0
HFD1_k127_1723210_19 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 303.0
HFD1_k127_1723210_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 7.635e-253 790.0
HFD1_k127_1723210_20 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 311.0
HFD1_k127_1723210_21 protein MJ0014 - Methanococcus jannaschii gi 1590824 gb AAB97992.1 (U67460) conserved K07450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004678 279.0
HFD1_k127_1723210_22 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002698 253.0
HFD1_k127_1723210_23 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001416 246.0
HFD1_k127_1723210_24 - K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000002247 228.0
HFD1_k127_1723210_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000002531 229.0
HFD1_k127_1723210_26 - - - - 0.000000000000000000000000000000000000000000000000000000000003537 218.0
HFD1_k127_1723210_27 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000005039 213.0
HFD1_k127_1723210_28 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000004935 216.0
HFD1_k127_1723210_29 - - - - 0.0000000000000000000000000000000000000000000000001066 188.0
HFD1_k127_1723210_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.079e-246 769.0
HFD1_k127_1723210_30 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000006222 186.0
HFD1_k127_1723210_31 cellulose binding - - - 0.00000000000000000000000000000000000000013 172.0
HFD1_k127_1723210_32 Polymer-forming cytoskeletal K12287 - - 0.0000000000000000000000000000000000000004337 162.0
HFD1_k127_1723210_33 Amidohydrolase family - - - 0.000000000000000000000000000000000000001434 158.0
HFD1_k127_1723210_34 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000000000000000829 146.0
HFD1_k127_1723210_35 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000006993 146.0
HFD1_k127_1723210_36 - - - - 0.00000000000000000000000000000003238 128.0
HFD1_k127_1723210_37 - K07112 - - 0.0000000000000000000000000000004666 128.0
HFD1_k127_1723210_38 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000007146 123.0
HFD1_k127_1723210_39 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000001147 121.0
HFD1_k127_1723210_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.58e-234 732.0
HFD1_k127_1723210_41 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000007768 112.0
HFD1_k127_1723210_42 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000002284 102.0
HFD1_k127_1723210_43 - - - - 0.0000000000000000000036 96.0
HFD1_k127_1723210_44 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000485 100.0
HFD1_k127_1723210_45 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10126 - - 0.000000000000000002526 91.0
HFD1_k127_1723210_46 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000002099 81.0
HFD1_k127_1723210_47 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000004579 88.0
HFD1_k127_1723210_48 Maltose operon periplasmic protein precursor (MalM) K05775 - - 0.00000000000001352 83.0
HFD1_k127_1723210_49 carbohydrate binding K06238,K14965,K17495,K19721 - - 0.00000000000005807 86.0
HFD1_k127_1723210_5 Sigma-54 interaction domain K07714,K07715 - - 7.395e-197 623.0
HFD1_k127_1723210_50 Ami_3 K01448 - 3.5.1.28 0.0000000000008926 80.0
HFD1_k127_1723210_51 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000008643 72.0
HFD1_k127_1723210_52 Sporulation and spore germination - - - 0.0000000000315 73.0
HFD1_k127_1723210_53 Sulphur transport K07112 - - 0.00000004857 57.0
HFD1_k127_1723210_54 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00001587 49.0
HFD1_k127_1723210_55 Heavy-metal-associated domain K07213 - - 0.00007287 49.0
HFD1_k127_1723210_6 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 609.0
HFD1_k127_1723210_7 Glycosyl transferase family group 2 K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 567.0
HFD1_k127_1723210_8 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 516.0
HFD1_k127_1723210_9 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 443.0
HFD1_k127_1732118_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 574.0
HFD1_k127_1732118_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 282.0
HFD1_k127_1732118_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000005089 200.0
HFD1_k127_1732118_3 peptidase - - - 0.00000000000000000000000001698 117.0
HFD1_k127_1821746_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 2679.0
HFD1_k127_1821746_1 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 300.0
HFD1_k127_1821746_2 RibD C-terminal domain K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000002337 205.0
HFD1_k127_1821746_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000197 156.0
HFD1_k127_1821746_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000003099 147.0
HFD1_k127_1821746_5 helicase activity K06915 - - 0.000000000000000000000000003668 112.0
HFD1_k127_1821746_6 DnaK suppressor protein K06204 - - 0.0000000000000000000006067 99.0
HFD1_k127_1821746_7 - - - - 0.0000000000000004765 78.0
HFD1_k127_1844182_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 2.154e-243 765.0
HFD1_k127_1844182_1 Domain of unknown function (DUF4139) - - - 1.235e-197 628.0
HFD1_k127_1844182_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000003349 195.0
HFD1_k127_1844182_11 part of a sulfur-relay system K11179 - - 0.000000000000000000000003579 104.0
HFD1_k127_1844182_12 Putative zinc-finger - - - 0.0000000000003548 81.0
HFD1_k127_1844182_13 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000005658 66.0
HFD1_k127_1844182_14 radical SAM domain protein - - - 0.00000001102 62.0
HFD1_k127_1844182_2 Thioredoxin domain K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 483.0
HFD1_k127_1844182_3 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 430.0
HFD1_k127_1844182_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 416.0
HFD1_k127_1844182_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 409.0
HFD1_k127_1844182_6 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 366.0
HFD1_k127_1844182_7 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000123 250.0
HFD1_k127_1844182_8 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000001787 225.0
HFD1_k127_1844182_9 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000003453 210.0
HFD1_k127_218141_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 388.0
HFD1_k127_218141_1 NlpC/P60 family K20742 - 3.4.14.13 0.0000000000000008279 88.0
HFD1_k127_218575_0 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 481.0
HFD1_k127_218575_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 448.0
HFD1_k127_218575_10 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000001947 188.0
HFD1_k127_218575_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000001525 122.0
HFD1_k127_218575_12 small metal-binding protein - - - 0.00000001982 61.0
HFD1_k127_218575_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 402.0
HFD1_k127_218575_3 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 376.0
HFD1_k127_218575_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 308.0
HFD1_k127_218575_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 290.0
HFD1_k127_218575_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 296.0
HFD1_k127_218575_7 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002846 288.0
HFD1_k127_218575_8 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003909 286.0
HFD1_k127_218575_9 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000001798 201.0
HFD1_k127_232920_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1476.0
HFD1_k127_232920_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 3e-323 995.0
HFD1_k127_232920_10 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 609.0
HFD1_k127_232920_100 cyclic nucleotide-binding - - - 0.000000000000000000000000000008172 124.0
HFD1_k127_232920_101 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000003384 120.0
HFD1_k127_232920_102 sulfur carrier activity - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0033554,GO:0042592,GO:0048878,GO:0050896,GO:0051716,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000001903 124.0
HFD1_k127_232920_103 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000005556 117.0
HFD1_k127_232920_104 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000005027 108.0
HFD1_k127_232920_105 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000002547 94.0
HFD1_k127_232920_106 peptidyl-tyrosine sulfation - - - 0.000000000000000000002938 102.0
HFD1_k127_232920_107 - - - - 0.0000000000000000000123 94.0
HFD1_k127_232920_108 - - - - 0.000000000000000001711 85.0
HFD1_k127_232920_109 Protein of unknown function (DUF402) - - - 0.000000000000000003943 90.0
HFD1_k127_232920_11 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 600.0
HFD1_k127_232920_110 Ribosome-associated heat shock protein implicated in recycling of 50S subunit - - - 0.00000000000000001838 85.0
HFD1_k127_232920_112 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000007668 78.0
HFD1_k127_232920_114 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191 - - 0.0000000000002489 71.0
HFD1_k127_232920_115 Copper chaperone PCu(A)C K09796 - - 0.000000000006101 72.0
HFD1_k127_232920_116 Universal stress protein family - - - 0.0000000007245 68.0
HFD1_k127_232920_117 - - - - 0.000000002101 68.0
HFD1_k127_232920_118 Protein of unknown function (DUF3185) - - - 0.00002397 49.0
HFD1_k127_232920_119 Cytochrome c554 and c-prime - - - 0.00004094 54.0
HFD1_k127_232920_12 Orn/Lys/Arg decarboxylase, C-terminal domain K01582,K01585 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.18,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 582.0
HFD1_k127_232920_120 Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin K04085 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00004446 49.0
HFD1_k127_232920_121 membrane protein TerC - - - 0.0001407 48.0
HFD1_k127_232920_122 PFAM DsrE DsrF-like family - - - 0.0002746 48.0
HFD1_k127_232920_13 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 576.0
HFD1_k127_232920_14 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 572.0
HFD1_k127_232920_15 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 583.0
HFD1_k127_232920_16 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 544.0
HFD1_k127_232920_17 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 521.0
HFD1_k127_232920_18 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 484.0
HFD1_k127_232920_19 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 481.0
HFD1_k127_232920_2 Heat shock 70 kDa protein K04043 - - 8.729e-299 928.0
HFD1_k127_232920_20 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 477.0
HFD1_k127_232920_21 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 479.0
HFD1_k127_232920_22 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 480.0
HFD1_k127_232920_23 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 457.0
HFD1_k127_232920_24 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 465.0
HFD1_k127_232920_25 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 451.0
HFD1_k127_232920_26 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 417.0
HFD1_k127_232920_27 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 405.0
HFD1_k127_232920_28 phosphorelay sensor kinase activity K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 400.0
HFD1_k127_232920_29 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 378.0
HFD1_k127_232920_3 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.899e-264 833.0
HFD1_k127_232920_30 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 377.0
HFD1_k127_232920_31 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 372.0
HFD1_k127_232920_32 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 346.0
HFD1_k127_232920_33 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 350.0
HFD1_k127_232920_34 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 350.0
HFD1_k127_232920_35 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 349.0
HFD1_k127_232920_36 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 338.0
HFD1_k127_232920_37 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 340.0
HFD1_k127_232920_39 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 332.0
HFD1_k127_232920_4 PFAM Radical SAM - - - 4.657e-255 806.0
HFD1_k127_232920_40 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 335.0
HFD1_k127_232920_41 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 338.0
HFD1_k127_232920_42 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 333.0
HFD1_k127_232920_43 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 319.0
HFD1_k127_232920_44 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 316.0
HFD1_k127_232920_45 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 320.0
HFD1_k127_232920_46 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 329.0
HFD1_k127_232920_47 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 308.0
HFD1_k127_232920_48 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 310.0
HFD1_k127_232920_49 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 304.0
HFD1_k127_232920_5 membrane - - - 3.834e-224 711.0
HFD1_k127_232920_50 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 323.0
HFD1_k127_232920_51 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 304.0
HFD1_k127_232920_52 HrcA protein C terminal domain K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 305.0
HFD1_k127_232920_54 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 297.0
HFD1_k127_232920_55 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 310.0
HFD1_k127_232920_56 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 288.0
HFD1_k127_232920_57 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 284.0
HFD1_k127_232920_58 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003872 283.0
HFD1_k127_232920_59 Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004642 275.0
HFD1_k127_232920_6 Major facilitator - - - 4.474e-211 663.0
HFD1_k127_232920_60 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000104 272.0
HFD1_k127_232920_61 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002491 282.0
HFD1_k127_232920_62 channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001638 262.0
HFD1_k127_232920_63 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003008 265.0
HFD1_k127_232920_64 3-beta hydroxysteroid dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001531 260.0
HFD1_k127_232920_65 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000001595 254.0
HFD1_k127_232920_66 anaerobic electron transport chain - GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002283 272.0
HFD1_k127_232920_67 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002464 251.0
HFD1_k127_232920_68 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001462 251.0
HFD1_k127_232920_69 CMP dCMP deaminase, zinc-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006671 247.0
HFD1_k127_232920_7 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 2.651e-204 651.0
HFD1_k127_232920_70 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000111 242.0
HFD1_k127_232920_71 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000037 229.0
HFD1_k127_232920_72 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000001255 228.0
HFD1_k127_232920_73 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000002618 224.0
HFD1_k127_232920_74 Domain of unknown function (DUF1848) - - - 0.00000000000000000000000000000000000000000000000000000000000004794 224.0
HFD1_k127_232920_75 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000002757 231.0
HFD1_k127_232920_76 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000003804 208.0
HFD1_k127_232920_77 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000007071 201.0
HFD1_k127_232920_78 MoaC family K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000003622 192.0
HFD1_k127_232920_79 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000005031 194.0
HFD1_k127_232920_8 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.707e-202 643.0
HFD1_k127_232920_80 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000222 196.0
HFD1_k127_232920_81 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000001346 182.0
HFD1_k127_232920_82 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000005543 183.0
HFD1_k127_232920_83 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000001116 185.0
HFD1_k127_232920_85 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000007535 164.0
HFD1_k127_232920_86 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000004341 162.0
HFD1_k127_232920_87 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000009676 158.0
HFD1_k127_232920_88 - - - - 0.00000000000000000000000000000000000000003807 172.0
HFD1_k127_232920_89 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000005895 151.0
HFD1_k127_232920_9 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.185e-196 618.0
HFD1_k127_232920_90 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000002527 145.0
HFD1_k127_232920_91 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000006955 146.0
HFD1_k127_232920_92 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000001963 156.0
HFD1_k127_232920_93 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000113 147.0
HFD1_k127_232920_94 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000001175 139.0
HFD1_k127_232920_95 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000001027 135.0
HFD1_k127_232920_96 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000002262 132.0
HFD1_k127_232920_97 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.0000000000000000000000000000004305 128.0
HFD1_k127_232920_99 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000008137 125.0
HFD1_k127_2436925_0 FAD binding domain K00394 - 1.8.99.2 0.0 1055.0
HFD1_k127_2436925_1 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1e-323 1006.0
HFD1_k127_2436925_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 7.66e-322 997.0
HFD1_k127_2436925_3 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 554.0
HFD1_k127_2436925_4 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 370.0
HFD1_k127_2436925_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 314.0
HFD1_k127_2436925_6 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 294.0
HFD1_k127_2436925_7 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000001008 186.0
HFD1_k127_2436925_8 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000001003 162.0
HFD1_k127_2436925_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000001101 111.0
HFD1_k127_249829_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1505.0
HFD1_k127_249829_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.935e-321 1005.0
HFD1_k127_249829_10 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 1.361e-201 643.0
HFD1_k127_249829_100 - - - - 0.00000000000005851 80.0
HFD1_k127_249829_101 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000004365 66.0
HFD1_k127_249829_103 electron transfer activity K05337,K17247 - - 0.00000000007276 64.0
HFD1_k127_249829_104 - - - - 0.0000000004444 65.0
HFD1_k127_249829_105 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000003703 63.0
HFD1_k127_249829_106 energy transducer activity K03832 - - 0.000000004479 67.0
HFD1_k127_249829_108 COG NOG19146 non supervised orthologous group - - - 0.0000000557 56.0
HFD1_k127_249829_109 PFAM IstB domain protein ATP-binding protein - - - 0.00000009365 57.0
HFD1_k127_249829_11 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.577e-195 616.0
HFD1_k127_249829_110 Belongs to the ompA family K03286 - - 0.0000001848 56.0
HFD1_k127_249829_112 alginic acid biosynthetic process K10297 - - 0.0000004698 52.0
HFD1_k127_249829_113 - - - - 0.0000005188 54.0
HFD1_k127_249829_114 Transcriptional regulatory protein, C terminal - - - 0.00002377 55.0
HFD1_k127_249829_117 PBS lyase HEAT-like repeat - - - 0.0001462 53.0
HFD1_k127_249829_118 Putative diguanylate phosphodiesterase - - - 0.0001603 46.0
HFD1_k127_249829_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.554e-194 613.0
HFD1_k127_249829_120 Protein of unknown function DUF116 - - - 0.0003982 46.0
HFD1_k127_249829_121 - - - - 0.000958 45.0
HFD1_k127_249829_122 Transposase K07496 - - 0.0009726 42.0
HFD1_k127_249829_13 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 562.0
HFD1_k127_249829_14 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 544.0
HFD1_k127_249829_15 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 542.0
HFD1_k127_249829_16 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 542.0
HFD1_k127_249829_17 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 518.0
HFD1_k127_249829_18 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 509.0
HFD1_k127_249829_19 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 499.0
HFD1_k127_249829_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 5.816e-320 1005.0
HFD1_k127_249829_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 471.0
HFD1_k127_249829_21 Chalcone and stilbene synthases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 470.0
HFD1_k127_249829_22 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 451.0
HFD1_k127_249829_23 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 434.0
HFD1_k127_249829_24 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 426.0
HFD1_k127_249829_25 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 426.0
HFD1_k127_249829_26 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 393.0
HFD1_k127_249829_27 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 390.0
HFD1_k127_249829_28 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 382.0
HFD1_k127_249829_29 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 380.0
HFD1_k127_249829_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.104e-305 956.0
HFD1_k127_249829_30 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 378.0
HFD1_k127_249829_31 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 360.0
HFD1_k127_249829_32 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 354.0
HFD1_k127_249829_33 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 341.0
HFD1_k127_249829_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 341.0
HFD1_k127_249829_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 327.0
HFD1_k127_249829_36 Clp protease K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 312.0
HFD1_k127_249829_37 Bacterial trigger factor protein (TF) C-terminus K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 309.0
HFD1_k127_249829_38 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 295.0
HFD1_k127_249829_39 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 301.0
HFD1_k127_249829_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.036e-293 909.0
HFD1_k127_249829_40 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 299.0
HFD1_k127_249829_41 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 297.0
HFD1_k127_249829_42 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 293.0
HFD1_k127_249829_43 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 293.0
HFD1_k127_249829_44 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 282.0
HFD1_k127_249829_45 ATP adenylyltransferase K00988 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000133 286.0
HFD1_k127_249829_46 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006116 263.0
HFD1_k127_249829_47 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000387 278.0
HFD1_k127_249829_48 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000572 272.0
HFD1_k127_249829_49 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003896 262.0
HFD1_k127_249829_5 PFAM Transketolase K00615 - 2.2.1.1 2.84e-242 764.0
HFD1_k127_249829_50 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001423 249.0
HFD1_k127_249829_51 Belongs to the ompA family K12216 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001506 249.0
HFD1_k127_249829_52 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003935 247.0
HFD1_k127_249829_53 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008288 245.0
HFD1_k127_249829_54 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000005238 233.0
HFD1_k127_249829_55 - - - - 0.000000000000000000000000000000000000000000000000000000000000000009553 240.0
HFD1_k127_249829_56 PFAM flavin reductase domain protein FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000009045 226.0
HFD1_k127_249829_57 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000002115 229.0
HFD1_k127_249829_58 Putative transposase DNA-binding domain K07496 - - 0.000000000000000000000000000000000000000000000000000000000000001586 224.0
HFD1_k127_249829_59 NOG31153 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000009986 228.0
HFD1_k127_249829_6 Protein of unknown function, DUF255 K06888 - - 1.815e-229 729.0
HFD1_k127_249829_60 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000001009 229.0
HFD1_k127_249829_61 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000000007759 207.0
HFD1_k127_249829_62 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000003331 215.0
HFD1_k127_249829_63 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000452 206.0
HFD1_k127_249829_64 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000000000002937 198.0
HFD1_k127_249829_65 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000001468 196.0
HFD1_k127_249829_66 COG1335 Amidases related to nicotinamidase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000002011 196.0
HFD1_k127_249829_67 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000262 197.0
HFD1_k127_249829_68 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000131 195.0
HFD1_k127_249829_69 AMMECR1 K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000001534 191.0
HFD1_k127_249829_7 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 3.746e-223 708.0
HFD1_k127_249829_70 NADH ubiquinone oxidoreductase 24 kD subunit K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000000001709 189.0
HFD1_k127_249829_71 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000000000000000000000000002315 192.0
HFD1_k127_249829_72 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000002472 187.0
HFD1_k127_249829_73 to the N-terminal region of K07491 - - 0.00000000000000000000000000000000000000000000000006734 183.0
HFD1_k127_249829_74 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.00000000000000000000000000000000000000000000001351 179.0
HFD1_k127_249829_75 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000000000000000000000000002794 173.0
HFD1_k127_249829_76 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000000002745 168.0
HFD1_k127_249829_77 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000001174 172.0
HFD1_k127_249829_78 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000002462 156.0
HFD1_k127_249829_79 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000009545 156.0
HFD1_k127_249829_8 General secretory system II, protein E domain protein K02652 - - 3.833e-219 695.0
HFD1_k127_249829_81 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000008333 144.0
HFD1_k127_249829_82 Type II secretory pathway, pseudopilin - - - 0.00000000000000000000000000000000007442 141.0
HFD1_k127_249829_83 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000001019 138.0
HFD1_k127_249829_84 SnoaL-like domain - - - 0.0000000000000000000000000000000005351 138.0
HFD1_k127_249829_85 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000001441 134.0
HFD1_k127_249829_86 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000006355 132.0
HFD1_k127_249829_87 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000003851 132.0
HFD1_k127_249829_88 Type II secretion system protein E K02243,K02652 - - 0.0000000000000000000000000007222 122.0
HFD1_k127_249829_89 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000006666 112.0
HFD1_k127_249829_9 Glycosyl hydrolase family 57 - - - 7.069e-204 657.0
HFD1_k127_249829_90 Outer membrane lipoprotein - - - 0.00000000000000000000000001321 121.0
HFD1_k127_249829_91 YtkA-like - - - 0.00000000000000000000002358 106.0
HFD1_k127_249829_92 RecX family K03565 - - 0.000000000000000000001089 101.0
HFD1_k127_249829_93 Belongs to the universal stress protein A family - - - 0.00000000000000000001097 97.0
HFD1_k127_249829_94 methyltransferase activity - - - 0.0000000000000000005161 95.0
HFD1_k127_249829_95 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000002529 89.0
HFD1_k127_249829_96 HEPN domain - - - 0.000000000000000006006 89.0
HFD1_k127_249829_97 transposase, IS891 IS1136 IS1341 family K07496 - - 0.000000000000001567 81.0
HFD1_k127_249829_99 - - - - 0.0000000000000527 81.0
HFD1_k127_2647995_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1581.0
HFD1_k127_2647995_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1090.0
HFD1_k127_2647995_10 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 548.0
HFD1_k127_2647995_11 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 567.0
HFD1_k127_2647995_12 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 533.0
HFD1_k127_2647995_13 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 492.0
HFD1_k127_2647995_14 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 482.0
HFD1_k127_2647995_15 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 481.0
HFD1_k127_2647995_16 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 482.0
HFD1_k127_2647995_17 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 443.0
HFD1_k127_2647995_18 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 429.0
HFD1_k127_2647995_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 386.0
HFD1_k127_2647995_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.273e-301 949.0
HFD1_k127_2647995_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 359.0
HFD1_k127_2647995_21 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 292.0
HFD1_k127_2647995_22 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 293.0
HFD1_k127_2647995_23 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006173 278.0
HFD1_k127_2647995_24 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006261 290.0
HFD1_k127_2647995_25 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 272.0
HFD1_k127_2647995_26 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000001804 241.0
HFD1_k127_2647995_27 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000004119 235.0
HFD1_k127_2647995_28 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001192 234.0
HFD1_k127_2647995_29 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000002464 224.0
HFD1_k127_2647995_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 6.552e-260 811.0
HFD1_k127_2647995_30 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000004033 226.0
HFD1_k127_2647995_31 NosL - - - 0.0000000000000000000000000000000000000000000000000000000002334 208.0
HFD1_k127_2647995_32 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000008253 197.0
HFD1_k127_2647995_33 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000001723 192.0
HFD1_k127_2647995_34 PFAM NosL family protein - - - 0.0000000000000000000000000000000000000000000003031 172.0
HFD1_k127_2647995_35 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.00000000000000000000000000000000000000000000212 171.0
HFD1_k127_2647995_36 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001632 163.0
HFD1_k127_2647995_37 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000004814 162.0
HFD1_k127_2647995_38 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000002605 154.0
HFD1_k127_2647995_39 Thioredoxin-like - - - 0.000000000000000000000000000000000002507 144.0
HFD1_k127_2647995_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 8.461e-230 723.0
HFD1_k127_2647995_40 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000000000002564 131.0
HFD1_k127_2647995_41 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000133 118.0
HFD1_k127_2647995_42 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.0000000000000000000000002643 116.0
HFD1_k127_2647995_43 - - - - 0.000000000000000000000004299 104.0
HFD1_k127_2647995_44 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000251 105.0
HFD1_k127_2647995_45 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000000001343 92.0
HFD1_k127_2647995_46 Domain of unknown function (DUF4253) - - - 0.0000000000000002757 89.0
HFD1_k127_2647995_47 signal-transduction protein containing cAMP-binding and CBS domains K07315 - 3.1.3.3 0.000000000000001969 86.0
HFD1_k127_2647995_49 Protein of unknown function (DUF465) K09794 - - 0.00000003371 58.0
HFD1_k127_2647995_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 3.847e-225 706.0
HFD1_k127_2647995_50 Binds directly to 16S ribosomal RNA K02968 - - 0.000007924 51.0
HFD1_k127_2647995_51 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0003912 43.0
HFD1_k127_2647995_6 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.897e-203 647.0
HFD1_k127_2647995_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.718e-202 636.0
HFD1_k127_2647995_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 587.0
HFD1_k127_2647995_9 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 593.0
HFD1_k127_2832826_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 517.0
HFD1_k127_2832826_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 452.0
HFD1_k127_2832826_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 347.0
HFD1_k127_2832826_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 302.0
HFD1_k127_2832826_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000003519 259.0
HFD1_k127_2832826_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001151 246.0
HFD1_k127_2832826_6 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001093 224.0
HFD1_k127_2832826_7 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000298 158.0
HFD1_k127_2832826_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000009554 127.0
HFD1_k127_287321_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1616.0
HFD1_k127_287321_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000003677 55.0
HFD1_k127_2951261_0 DEAD_2 K10844 - 3.6.4.12 0.0 1073.0
HFD1_k127_2951261_1 Staphylococcal nuclease homologues - - - 0.00000000000000000000000000000000003916 140.0
HFD1_k127_3140370_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.129e-255 802.0
HFD1_k127_3140370_1 glycolate transport K14393 - - 1.317e-226 716.0
HFD1_k127_3140370_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000001975 177.0
HFD1_k127_3140370_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000003739 149.0
HFD1_k127_3140370_4 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000001147 121.0
HFD1_k127_3140370_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000009157 67.0
HFD1_k127_3246112_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 6.035e-200 630.0
HFD1_k127_3246112_1 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000003746 237.0
HFD1_k127_3259538_0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 460.0
HFD1_k127_3259538_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003614 275.0
HFD1_k127_3259538_2 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000001752 179.0
HFD1_k127_3259538_3 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000003109 153.0
HFD1_k127_3259538_4 Cell surface protein - - - 0.000000000000000000000006142 117.0
HFD1_k127_3282103_0 Tim44 K02117,K08678,K11646,K15539,K17835,K21636 - 1.1.98.6,1.4.1.24,3.6.3.14,3.6.3.15,4.1.1.35,4.1.99.20 2.594e-228 735.0
HFD1_k127_3282103_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.367e-226 714.0
HFD1_k127_3282103_10 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 505.0
HFD1_k127_3282103_11 Ion transport 2 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 492.0
HFD1_k127_3282103_12 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 476.0
HFD1_k127_3282103_13 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 475.0
HFD1_k127_3282103_14 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 461.0
HFD1_k127_3282103_15 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 457.0
HFD1_k127_3282103_16 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 445.0
HFD1_k127_3282103_17 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 433.0
HFD1_k127_3282103_18 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 422.0
HFD1_k127_3282103_19 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 426.0
HFD1_k127_3282103_2 General secretory system II, protein E domain protein K02454 - - 3.063e-217 691.0
HFD1_k127_3282103_20 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 415.0
HFD1_k127_3282103_21 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 404.0
HFD1_k127_3282103_22 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K01008,K04487 - 2.7.9.3,2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 401.0
HFD1_k127_3282103_23 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 392.0
HFD1_k127_3282103_24 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 394.0
HFD1_k127_3282103_25 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 388.0
HFD1_k127_3282103_26 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 400.0
HFD1_k127_3282103_27 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 377.0
HFD1_k127_3282103_28 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 374.0
HFD1_k127_3282103_29 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 361.0
HFD1_k127_3282103_3 PFAM nickel-dependent hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 3.596e-197 621.0
HFD1_k127_3282103_30 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 380.0
HFD1_k127_3282103_31 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 355.0
HFD1_k127_3282103_32 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 339.0
HFD1_k127_3282103_33 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 313.0
HFD1_k127_3282103_34 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 300.0
HFD1_k127_3282103_35 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 295.0
HFD1_k127_3282103_36 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
HFD1_k127_3282103_37 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001863 275.0
HFD1_k127_3282103_38 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002982 267.0
HFD1_k127_3282103_39 Cytochrome b/b6/petB K03887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003894 260.0
HFD1_k127_3282103_4 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 633.0
HFD1_k127_3282103_40 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002717 254.0
HFD1_k127_3282103_41 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000002478 253.0
HFD1_k127_3282103_42 RNA 2'-O ribose methyltransferase substrate binding K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000002434 247.0
HFD1_k127_3282103_43 CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000002458 252.0
HFD1_k127_3282103_44 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000007514 235.0
HFD1_k127_3282103_45 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000002135 228.0
HFD1_k127_3282103_46 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000000008819 225.0
HFD1_k127_3282103_47 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000009118 216.0
HFD1_k127_3282103_48 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000002838 217.0
HFD1_k127_3282103_49 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000005758 203.0
HFD1_k127_3282103_5 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 616.0
HFD1_k127_3282103_50 - - - - 0.000000000000000000000000000000000000000000000000000000168 204.0
HFD1_k127_3282103_51 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000001047 192.0
HFD1_k127_3282103_52 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000323 184.0
HFD1_k127_3282103_53 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000004799 183.0
HFD1_k127_3282103_54 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000111 170.0
HFD1_k127_3282103_55 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000006121 175.0
HFD1_k127_3282103_56 PFAM pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000000000007738 163.0
HFD1_k127_3282103_57 - - - - 0.000000000000000000000000000000000000003464 156.0
HFD1_k127_3282103_58 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000000000000000001607 140.0
HFD1_k127_3282103_59 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000004451 120.0
HFD1_k127_3282103_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 580.0
HFD1_k127_3282103_60 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000009101 121.0
HFD1_k127_3282103_61 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.00000000000000000000000002253 109.0
HFD1_k127_3282103_62 Transposase K07496 - - 0.00000000000000000000000004281 113.0
HFD1_k127_3282103_63 - - - - 0.0000000000000000000000000777 112.0
HFD1_k127_3282103_64 Histidine kinase K02660,K11525 - - 0.0000000000000000000000006064 111.0
HFD1_k127_3282103_65 Diguanylate cyclase - - - 0.0000000000000000000002029 113.0
HFD1_k127_3282103_66 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000003219 102.0
HFD1_k127_3282103_67 Bacterial Ig-like domain 2 - - - 0.00000000000000000001041 102.0
HFD1_k127_3282103_68 general secretion pathway protein - - - 0.00000000000000000001118 100.0
HFD1_k127_3282103_69 Bacterial protein of unknown function (DUF922) - - - 0.00000000000000000004518 98.0
HFD1_k127_3282103_7 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 576.0
HFD1_k127_3282103_72 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001098 81.0
HFD1_k127_3282103_73 PFAM 4Fe-4S K00176 - 1.2.7.3 0.000000000000000815 78.0
HFD1_k127_3282103_74 PFAM Curli production assembly transport component CsgG - - - 0.00000000000005335 85.0
HFD1_k127_3282103_75 - - - - 0.00000000000006845 74.0
HFD1_k127_3282103_76 NADH flavin oxidoreductase NADH oxidase K00354 - 1.6.99.1 0.00000000000007826 74.0
HFD1_k127_3282103_77 Type II secretion system (T2SS), protein K K02460 - - 0.000000000003169 76.0
HFD1_k127_3282103_78 Type IV pilus assembly protein PilM; K02461 - - 0.0000000001025 74.0
HFD1_k127_3282103_79 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000001835 64.0
HFD1_k127_3282103_8 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 544.0
HFD1_k127_3282103_81 Prokaryotic N-terminal methylation motif - - - 0.000000004019 64.0
HFD1_k127_3282103_82 - - - - 0.000000009016 66.0
HFD1_k127_3282103_83 His Kinase A (phosphoacceptor) domain - - - 0.00000002864 67.0
HFD1_k127_3282103_84 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.00000007945 63.0
HFD1_k127_3282103_85 Domain of unknown function (DUF309) K09763 - - 0.00000009391 60.0
HFD1_k127_3282103_86 - - - - 0.0000007675 54.0
HFD1_k127_3282103_87 Prokaryotic N-terminal methylation motif K02459 - - 0.000001227 59.0
HFD1_k127_3282103_88 - - - - 0.000001248 57.0
HFD1_k127_3282103_89 translation initiation factor activity K03646 - - 0.000001382 56.0
HFD1_k127_3282103_9 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 535.0
HFD1_k127_3282103_91 Helix-turn-helix domain - - - 0.000003056 49.0
HFD1_k127_3282103_92 SurA N-terminal domain K03771 - 5.2.1.8 0.0000218 56.0
HFD1_k127_3282103_93 FOG TPR repeat - - - 0.00004969 53.0
HFD1_k127_3282103_95 - - - - 0.0008789 47.0
HFD1_k127_3344219_0 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 324.0
HFD1_k127_3344219_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 311.0
HFD1_k127_3344219_2 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000001235 185.0
HFD1_k127_3344219_3 GYD domain - - - 0.000000000000000000000000000000000000001792 149.0
HFD1_k127_3344219_4 Protein of unknown function (DUF3187) - - - 0.0000000000000000005783 98.0
HFD1_k127_3344219_5 Predicted RNA-binding protein - - - 0.0000004346 54.0
HFD1_k127_3636177_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1712.0
HFD1_k127_3636177_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.966e-255 804.0
HFD1_k127_3636177_10 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000161 197.0
HFD1_k127_3636177_11 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000001635 199.0
HFD1_k127_3636177_12 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000002644 190.0
HFD1_k127_3636177_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000105 153.0
HFD1_k127_3636177_14 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000001399 79.0
HFD1_k127_3636177_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000008459 68.0
HFD1_k127_3636177_16 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000001617 61.0
HFD1_k127_3636177_2 Arylsulfatase K01130 - 3.1.6.1 9.229e-240 751.0
HFD1_k127_3636177_3 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 539.0
HFD1_k127_3636177_4 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 535.0
HFD1_k127_3636177_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 417.0
HFD1_k127_3636177_6 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 337.0
HFD1_k127_3636177_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 316.0
HFD1_k127_3636177_8 TonB-dependent Receptor Plug K02014,K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000009737 244.0
HFD1_k127_3636177_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000002112 213.0
HFD1_k127_4099760_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 2.203e-211 666.0
HFD1_k127_4099760_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.205e-196 623.0
HFD1_k127_4099760_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 547.0
HFD1_k127_4099760_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 540.0
HFD1_k127_4099760_4 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 318.0
HFD1_k127_4099760_5 6-phosphogluconate dehydrogenase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000313 203.0
HFD1_k127_4099760_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000001431 169.0
HFD1_k127_4099760_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000002065 120.0
HFD1_k127_4099760_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000009824 113.0
HFD1_k127_4099760_9 cheY-homologous receiver domain K07315 - 3.1.3.3 0.000000000000007198 83.0
HFD1_k127_416955_0 PFAM ABC transporter related K06020 - 3.6.3.25 3.274e-300 928.0
HFD1_k127_416955_1 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000001078 180.0
HFD1_k127_416955_2 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000001089 154.0
HFD1_k127_416955_3 TonB-dependent receptor K02014,K02456,K02457,K02458,K10926,K10930,K10931 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840 - 0.00000000000000000000005103 116.0
HFD1_k127_416955_4 - - - - 0.000000000000000000005776 96.0
HFD1_k127_416955_5 - - - - 0.00000000001549 75.0
HFD1_k127_416955_6 cellulose binding K01179 - 3.2.1.4 0.00000000003817 77.0
HFD1_k127_4207181_0 asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 9.457e-206 660.0
HFD1_k127_4207181_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 567.0
HFD1_k127_4207181_10 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000349 218.0
HFD1_k127_4207181_11 Bacterial regulatory proteins, crp family - - - 0.0000000000000000000000000000000000000000000000000009099 192.0
HFD1_k127_4207181_12 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000001564 175.0
HFD1_k127_4207181_13 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000008912 164.0
HFD1_k127_4207181_14 polysaccharide deacetylase - - - 0.000000000000001352 87.0
HFD1_k127_4207181_15 fibronectin type III domain protein - - - 0.0000001041 59.0
HFD1_k127_4207181_2 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 501.0
HFD1_k127_4207181_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 413.0
HFD1_k127_4207181_4 Polysaccharide biosynthesis protein K03328 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 405.0
HFD1_k127_4207181_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 317.0
HFD1_k127_4207181_6 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 304.0
HFD1_k127_4207181_7 Pectate lyase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 300.0
HFD1_k127_4207181_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007871 255.0
HFD1_k127_4207181_9 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000003337 243.0
HFD1_k127_4222412_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1284.0
HFD1_k127_4222412_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1137.0
HFD1_k127_4222412_10 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 572.0
HFD1_k127_4222412_11 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 561.0
HFD1_k127_4222412_12 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 499.0
HFD1_k127_4222412_13 6 heme-binding sites - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 497.0
HFD1_k127_4222412_14 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 496.0
HFD1_k127_4222412_15 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 492.0
HFD1_k127_4222412_16 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 450.0
HFD1_k127_4222412_17 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 456.0
HFD1_k127_4222412_18 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 439.0
HFD1_k127_4222412_19 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 422.0
HFD1_k127_4222412_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.402e-303 949.0
HFD1_k127_4222412_20 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 432.0
HFD1_k127_4222412_21 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 403.0
HFD1_k127_4222412_22 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 387.0
HFD1_k127_4222412_23 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 385.0
HFD1_k127_4222412_24 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 381.0
HFD1_k127_4222412_25 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 374.0
HFD1_k127_4222412_26 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 383.0
HFD1_k127_4222412_27 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 381.0
HFD1_k127_4222412_28 N-terminal domain of galactosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 361.0
HFD1_k127_4222412_29 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 351.0
HFD1_k127_4222412_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.807e-267 841.0
HFD1_k127_4222412_30 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 354.0
HFD1_k127_4222412_31 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 351.0
HFD1_k127_4222412_32 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 352.0
HFD1_k127_4222412_33 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 339.0
HFD1_k127_4222412_34 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 319.0
HFD1_k127_4222412_35 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 307.0
HFD1_k127_4222412_36 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 303.0
HFD1_k127_4222412_37 proteolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 301.0
HFD1_k127_4222412_38 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 301.0
HFD1_k127_4222412_39 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 297.0
HFD1_k127_4222412_4 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.372e-249 788.0
HFD1_k127_4222412_40 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 300.0
HFD1_k127_4222412_41 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003732 273.0
HFD1_k127_4222412_42 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002672 265.0
HFD1_k127_4222412_43 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008507 266.0
HFD1_k127_4222412_44 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000006697 267.0
HFD1_k127_4222412_45 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000001582 252.0
HFD1_k127_4222412_46 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002217 250.0
HFD1_k127_4222412_47 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000001174 246.0
HFD1_k127_4222412_48 Atpase (Aaa K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000003659 244.0
HFD1_k127_4222412_49 -O-antigen K02847 - - 0.000000000000000000000000000000000000000000000000000000000000000000005703 251.0
HFD1_k127_4222412_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.63e-247 789.0
HFD1_k127_4222412_50 N-terminal domain of galactosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008116 240.0
HFD1_k127_4222412_51 Glycosyl transferase family 2 K13005 - 2.4.1.60 0.0000000000000000000000000000000000000000000000000000000000000001464 234.0
HFD1_k127_4222412_52 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000001101 227.0
HFD1_k127_4222412_53 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000004356 220.0
HFD1_k127_4222412_54 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000002408 205.0
HFD1_k127_4222412_55 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000009066 204.0
HFD1_k127_4222412_56 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000005862 199.0
HFD1_k127_4222412_57 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000007993 195.0
HFD1_k127_4222412_58 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000107 193.0
HFD1_k127_4222412_59 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000002271 197.0
HFD1_k127_4222412_6 Methyltransferase domain - - - 6.242e-233 724.0
HFD1_k127_4222412_60 Glycosyl transferase, family 2 K13683 GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000008179 191.0
HFD1_k127_4222412_61 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000000000000000000000000000005443 169.0
HFD1_k127_4222412_62 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000003135 164.0
HFD1_k127_4222412_63 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000005522 169.0
HFD1_k127_4222412_64 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000001589 159.0
HFD1_k127_4222412_65 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000001256 150.0
HFD1_k127_4222412_66 protein methyltransferase activity - - - 0.0000000000000000000000000000000006478 142.0
HFD1_k127_4222412_67 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000003166 135.0
HFD1_k127_4222412_68 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000003389 131.0
HFD1_k127_4222412_69 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000001575 124.0
HFD1_k127_4222412_7 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 2.505e-211 658.0
HFD1_k127_4222412_70 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000001001 121.0
HFD1_k127_4222412_71 - - - - 0.00000000000000000000000000002241 126.0
HFD1_k127_4222412_72 Protein conserved in bacteria K09764 - - 0.00000000000000000000000001382 111.0
HFD1_k127_4222412_73 Glycosyl transferases group 1 - - - 0.00000000000000000000000001471 123.0
HFD1_k127_4222412_74 Methyltransferase domain - - - 0.00000000000000000000000005179 117.0
HFD1_k127_4222412_75 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000001241 107.0
HFD1_k127_4222412_76 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.00000000000000000000002812 108.0
HFD1_k127_4222412_77 TfoX N-terminal domain - - - 0.00000000000000000000594 95.0
HFD1_k127_4222412_78 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000001038 88.0
HFD1_k127_4222412_79 Hsp20/alpha crystallin family - - - 0.000000000000000002833 90.0
HFD1_k127_4222412_8 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.549e-204 646.0
HFD1_k127_4222412_80 cytochrome C peroxidase - - - 0.000000000000000276 83.0
HFD1_k127_4222412_81 mttA/Hcf106 family K03116 - - 0.00000000000005592 73.0
HFD1_k127_4222412_82 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000001493 70.0
HFD1_k127_4222412_83 - - - - 0.000000000001633 72.0
HFD1_k127_4222412_84 - - - - 0.000000009172 64.0
HFD1_k127_4222412_85 - - - - 0.0000005211 57.0
HFD1_k127_4222412_87 Phytoene dehydrogenase K09835 - 5.2.1.13 0.0001956 53.0
HFD1_k127_4222412_88 unfolded protein binding K06142 - - 0.0002741 50.0
HFD1_k127_4222412_9 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.832e-195 621.0
HFD1_k127_4288899_0 Methylcobalamin coenzyme M methyltransferase K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001525 277.0
HFD1_k127_4288899_1 PFAM B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000004521 223.0
HFD1_k127_4288899_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000008177 209.0
HFD1_k127_4288899_3 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000134 121.0
HFD1_k127_448008_0 ABC transporter C-terminal domain K15738 - - 2.386e-238 752.0
HFD1_k127_448008_1 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 2.31e-206 654.0
HFD1_k127_448008_10 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 445.0
HFD1_k127_448008_11 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 409.0
HFD1_k127_448008_12 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 399.0
HFD1_k127_448008_13 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 368.0
HFD1_k127_448008_14 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 364.0
HFD1_k127_448008_15 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 306.0
HFD1_k127_448008_16 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 294.0
HFD1_k127_448008_17 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006665 273.0
HFD1_k127_448008_18 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000001146 253.0
HFD1_k127_448008_19 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000002058 242.0
HFD1_k127_448008_2 PFAM aminotransferase, class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 589.0
HFD1_k127_448008_20 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000002677 220.0
HFD1_k127_448008_21 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000001167 217.0
HFD1_k127_448008_22 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000007495 203.0
HFD1_k127_448008_23 domain protein - - - 0.00000000000000000000000000000000000000000000000005675 187.0
HFD1_k127_448008_24 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000000000000000000000000000001743 168.0
HFD1_k127_448008_25 HNH nucleases - - - 0.000000000000000000000000000000000000000002608 158.0
HFD1_k127_448008_26 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000021 145.0
HFD1_k127_448008_27 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000003538 138.0
HFD1_k127_448008_28 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001265 130.0
HFD1_k127_448008_29 phosphorelay signal transduction system - - - 0.000000000000000000000000000002201 124.0
HFD1_k127_448008_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 552.0
HFD1_k127_448008_30 protein kinase activity - - - 0.00000000000000000000000003656 115.0
HFD1_k127_448008_31 Protein of unknown function (DUF721) - - - 0.0000000000000000003581 93.0
HFD1_k127_448008_32 Domain of unknown function (DUF1844) - - - 0.000000000000000002184 91.0
HFD1_k127_448008_33 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000003359 89.0
HFD1_k127_448008_34 Rubrerythrin - - - 0.000000000000001337 85.0
HFD1_k127_448008_35 sirohydrochlorin cobaltochelatase activity K03794 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.4 0.0000000000002322 80.0
HFD1_k127_448008_36 Auxin Efflux Carrier K07088 - - 0.0000000000003057 72.0
HFD1_k127_448008_37 Late embryogenesis abundant protein - - - 0.000000006079 64.0
HFD1_k127_448008_38 Tetratricopeptide repeat - - - 0.00000005989 60.0
HFD1_k127_448008_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 531.0
HFD1_k127_448008_5 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 482.0
HFD1_k127_448008_6 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 474.0
HFD1_k127_448008_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 466.0
HFD1_k127_448008_8 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 460.0
HFD1_k127_448008_9 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 479.0
HFD1_k127_4493880_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 531.0
HFD1_k127_4493880_1 spore germination - - - 0.0000000000000000000000000000000000000000000006126 177.0
HFD1_k127_4493880_2 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K10942 - 2.7.13.3 0.0000000000000000000000000000000000000009679 155.0
HFD1_k127_4532893_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 3.343e-258 805.0
HFD1_k127_4532893_1 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 474.0
HFD1_k127_4532893_10 Domain of unknown function (DUF4136) - - - 0.00000000000001721 80.0
HFD1_k127_4532893_11 PFAM PRC-barrel domain - - - 0.0000000002376 66.0
HFD1_k127_4532893_12 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000008929 53.0
HFD1_k127_4532893_13 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0004734 47.0
HFD1_k127_4532893_2 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 427.0
HFD1_k127_4532893_3 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 415.0
HFD1_k127_4532893_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 334.0
HFD1_k127_4532893_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000002503 167.0
HFD1_k127_4532893_6 Ion channel - - - 0.0000000000000000000000000000009245 130.0
HFD1_k127_4532893_7 - - - - 0.00000000000000000000000001322 116.0
HFD1_k127_4532893_8 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000004149 113.0
HFD1_k127_4532893_9 Glycogen debranching enzyme - - - 0.00000000000000002864 83.0
HFD1_k127_4805571_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1253.0
HFD1_k127_4805571_1 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1210.0
HFD1_k127_4805571_10 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 461.0
HFD1_k127_4805571_11 PFAM sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 325.0
HFD1_k127_4805571_12 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 312.0
HFD1_k127_4805571_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008215 268.0
HFD1_k127_4805571_14 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000002815 267.0
HFD1_k127_4805571_15 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001466 255.0
HFD1_k127_4805571_16 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000185 246.0
HFD1_k127_4805571_17 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000006172 201.0
HFD1_k127_4805571_18 Protein of unknown function (DUF3124) - - - 0.000000000000000000000000000000000000000000000002136 178.0
HFD1_k127_4805571_19 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000007124 172.0
HFD1_k127_4805571_2 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1161.0
HFD1_k127_4805571_20 - - - - 0.00000000000000000000000000000000000000000008664 170.0
HFD1_k127_4805571_21 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000005136 121.0
HFD1_k127_4805571_22 transmembrane transport - - - 0.000000000000000000000000002266 120.0
HFD1_k127_4805571_23 Pilus assembly protein K02662 - - 0.00000000000000000007816 100.0
HFD1_k127_4805571_24 BON domain - - - 0.000000004097 66.0
HFD1_k127_4805571_25 PFAM Fimbrial assembly family protein K02461,K02662,K02663,K12289 - - 0.000000005534 65.0
HFD1_k127_4805571_28 Pilus assembly protein, PilO K02664 - - 0.000000009471 64.0
HFD1_k127_4805571_29 - - - - 0.000002867 57.0
HFD1_k127_4805571_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 3.815e-289 902.0
HFD1_k127_4805571_4 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 586.0
HFD1_k127_4805571_5 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 533.0
HFD1_k127_4805571_6 hydroxypyruvate reductase K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 516.0
HFD1_k127_4805571_7 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 514.0
HFD1_k127_4805571_8 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 514.0
HFD1_k127_4805571_9 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 452.0
HFD1_k127_49911_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 3.198e-265 829.0
HFD1_k127_49911_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 421.0
HFD1_k127_49911_2 4Fe-4S ferredoxin K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 300.0
HFD1_k127_49911_3 Polysulfide reductase - - - 0.000000000000000000000000000000000000000000000000000000001704 211.0
HFD1_k127_49911_4 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000000000000000008463 111.0
HFD1_k127_5003880_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 3.574e-237 768.0
HFD1_k127_5003880_1 Sulfate permease family K01673,K03321 - 4.2.1.1 4.82e-229 723.0
HFD1_k127_5003880_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 424.0
HFD1_k127_5003880_11 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 387.0
HFD1_k127_5003880_12 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 344.0
HFD1_k127_5003880_13 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 331.0
HFD1_k127_5003880_14 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 297.0
HFD1_k127_5003880_15 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004236 282.0
HFD1_k127_5003880_16 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004304 266.0
HFD1_k127_5003880_17 PFAM NADH Ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000006799 237.0
HFD1_k127_5003880_18 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000002477 236.0
HFD1_k127_5003880_19 4Fe-4S double cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004206 238.0
HFD1_k127_5003880_2 Belongs to the RtcB family K14415 - 6.5.1.3 3.663e-208 657.0
HFD1_k127_5003880_20 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000001672 233.0
HFD1_k127_5003880_21 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000001744 217.0
HFD1_k127_5003880_22 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000001982 191.0
HFD1_k127_5003880_23 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000003546 157.0
HFD1_k127_5003880_24 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000004646 151.0
HFD1_k127_5003880_25 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000001698 136.0
HFD1_k127_5003880_26 - - - - 0.0000000000000000000000000000001431 130.0
HFD1_k127_5003880_27 Hydrolase K21471 - - 0.00000000000000000000000002378 124.0
HFD1_k127_5003880_28 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000006205 98.0
HFD1_k127_5003880_29 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000001285 98.0
HFD1_k127_5003880_3 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 2.639e-198 640.0
HFD1_k127_5003880_30 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000007335 93.0
HFD1_k127_5003880_31 HEPN domain - - - 0.0000000000000002184 83.0
HFD1_k127_5003880_32 to the N-terminal region of K07491 - - 0.000000000000002616 78.0
HFD1_k127_5003880_33 Cytochrome c7 and related cytochrome c - - - 0.00000000009022 66.0
HFD1_k127_5003880_34 cell envelope organization K05807,K08309 - - 0.0000000008633 68.0
HFD1_k127_5003880_35 Thioredoxin domain - - - 0.000000001007 68.0
HFD1_k127_5003880_4 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 1.635e-195 621.0
HFD1_k127_5003880_5 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 495.0
HFD1_k127_5003880_6 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 471.0
HFD1_k127_5003880_7 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 454.0
HFD1_k127_5003880_8 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 446.0
HFD1_k127_5003880_9 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 437.0
HFD1_k127_5018020_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 3e-323 1001.0
HFD1_k127_5018020_1 Aconitase C-terminal domain K01681 - 4.2.1.3 1.83e-322 994.0
HFD1_k127_5018020_10 PFAM Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 381.0
HFD1_k127_5018020_11 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 366.0
HFD1_k127_5018020_12 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 339.0
HFD1_k127_5018020_13 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 327.0
HFD1_k127_5018020_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005876 289.0
HFD1_k127_5018020_16 SMART Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008076 268.0
HFD1_k127_5018020_17 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003861 268.0
HFD1_k127_5018020_18 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
HFD1_k127_5018020_19 PFAM Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007491 253.0
HFD1_k127_5018020_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 2.082e-319 1000.0
HFD1_k127_5018020_20 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001436 217.0
HFD1_k127_5018020_21 PFAM Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000009932 178.0
HFD1_k127_5018020_22 - - - - 0.00000000000000000000000000000000000000000008311 171.0
HFD1_k127_5018020_23 Putative methyltransferase - - - 0.000000000000000000000000002288 124.0
HFD1_k127_5018020_24 - - - - 0.0000000000000001707 84.0
HFD1_k127_5018020_25 SMART Rhodanese domain protein - - - 0.00000000000003461 81.0
HFD1_k127_5018020_3 Amino acid permease - - - 7.824e-257 808.0
HFD1_k127_5018020_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 4.171e-253 795.0
HFD1_k127_5018020_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.666e-248 777.0
HFD1_k127_5018020_6 SMART Elongator protein 3 MiaB NifB - - - 1.175e-206 652.0
HFD1_k127_5018020_7 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 591.0
HFD1_k127_5018020_8 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 522.0
HFD1_k127_5018020_9 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 503.0
HFD1_k127_5208600_0 CBS domain containing protein K00974 - 2.7.7.72 4.675e-262 835.0
HFD1_k127_5208600_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.327e-213 672.0
HFD1_k127_5208600_10 TIGRFAM Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 383.0
HFD1_k127_5208600_11 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 364.0
HFD1_k127_5208600_12 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 366.0
HFD1_k127_5208600_13 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 363.0
HFD1_k127_5208600_14 integrase domain protein SAM domain protein K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 319.0
HFD1_k127_5208600_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 323.0
HFD1_k127_5208600_16 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 303.0
HFD1_k127_5208600_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 300.0
HFD1_k127_5208600_18 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 293.0
HFD1_k127_5208600_19 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000324 290.0
HFD1_k127_5208600_2 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 586.0
HFD1_k127_5208600_20 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005259 285.0
HFD1_k127_5208600_21 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007642 280.0
HFD1_k127_5208600_22 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009368 264.0
HFD1_k127_5208600_23 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001384 266.0
HFD1_k127_5208600_24 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002132 262.0
HFD1_k127_5208600_25 regulatory protein IclR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 257.0
HFD1_k127_5208600_26 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000622 252.0
HFD1_k127_5208600_27 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001187 251.0
HFD1_k127_5208600_28 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000004464 251.0
HFD1_k127_5208600_29 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004053 250.0
HFD1_k127_5208600_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 584.0
HFD1_k127_5208600_30 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000001999 253.0
HFD1_k127_5208600_31 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000005383 235.0
HFD1_k127_5208600_32 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000001194 227.0
HFD1_k127_5208600_33 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000022 211.0
HFD1_k127_5208600_34 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000001004 214.0
HFD1_k127_5208600_35 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000001493 207.0
HFD1_k127_5208600_36 metal ion binding - - - 0.000000000000000000000000000000000000000000000000000000002557 211.0
HFD1_k127_5208600_37 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000001042 194.0
HFD1_k127_5208600_38 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000002083 198.0
HFD1_k127_5208600_39 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000004364 201.0
HFD1_k127_5208600_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 567.0
HFD1_k127_5208600_40 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000000004385 203.0
HFD1_k127_5208600_41 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000006489 192.0
HFD1_k127_5208600_42 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000519 187.0
HFD1_k127_5208600_43 Secondary thiamine-phosphate synthase enzyme - - - 0.00000000000000000000000000000000000000000000000008597 181.0
HFD1_k127_5208600_44 - - - - 0.0000000000000000000000000000000000000000000000001885 185.0
HFD1_k127_5208600_45 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000003027 184.0
HFD1_k127_5208600_46 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000005873 186.0
HFD1_k127_5208600_47 SMART GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000001572 177.0
HFD1_k127_5208600_48 self proteolysis - - - 0.0000000000000000000000000000000000000000052 168.0
HFD1_k127_5208600_49 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000002011 156.0
HFD1_k127_5208600_5 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 558.0
HFD1_k127_5208600_50 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000006993 138.0
HFD1_k127_5208600_51 - - - - 0.00000000000000000000000000003347 128.0
HFD1_k127_5208600_52 cobalt ion transport K02009 - - 0.00000000000000000000000001937 112.0
HFD1_k127_5208600_53 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000004048 111.0
HFD1_k127_5208600_54 Peptidase family M23 - - - 0.0000000000000000000001185 111.0
HFD1_k127_5208600_55 PBS lyase HEAT-like repeat - - - 0.00000000000000000001298 108.0
HFD1_k127_5208600_56 Protein of unknown function (DUF3617) - - - 0.000000000000000000145 94.0
HFD1_k127_5208600_57 response regulator, receiver K07684 - - 0.000000000000000002153 93.0
HFD1_k127_5208600_58 peptidyl-tyrosine sulfation - - - 0.000000000000007732 80.0
HFD1_k127_5208600_6 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 548.0
HFD1_k127_5208600_61 Sporulation related domain - - - 0.000000000001493 77.0
HFD1_k127_5208600_62 Domain of unknown function (DUF3786) - - - 0.00000000008673 70.0
HFD1_k127_5208600_63 - - - - 0.0000001722 53.0
HFD1_k127_5208600_64 pilus assembly protein PilW K02672 - - 0.000006199 58.0
HFD1_k127_5208600_66 Type II transport protein GspH K08084 - - 0.00003245 53.0
HFD1_k127_5208600_67 Fic/DOC family - - - 0.0004021 47.0
HFD1_k127_5208600_7 B3/4 domain K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 542.0
HFD1_k127_5208600_8 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 511.0
HFD1_k127_5208600_9 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 422.0
HFD1_k127_5239543_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1464.0
HFD1_k127_5239543_1 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 426.0
HFD1_k127_5239543_10 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000005068 200.0
HFD1_k127_5239543_11 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000007812 193.0
HFD1_k127_5239543_12 Domain of unknown function (DUF4145) - - - 0.00000000000000000000000000000000000000000000006466 177.0
HFD1_k127_5239543_13 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000002692 160.0
HFD1_k127_5239543_14 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000000000008361 165.0
HFD1_k127_5239543_15 HAMP domain - - - 0.00000000000000000000000000000000000000004182 164.0
HFD1_k127_5239543_16 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000001377 129.0
HFD1_k127_5239543_18 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000001636 97.0
HFD1_k127_5239543_19 negative regulation of establishment of protein localization K02570 GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032879,GO:0032880,GO:0033218,GO:0042277,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0065007,GO:0070201,GO:0090087,GO:1904950 - 0.0000000000000000006868 93.0
HFD1_k127_5239543_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 418.0
HFD1_k127_5239543_20 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000007094 67.0
HFD1_k127_5239543_22 PFAM Tetratricopeptide repeat - - - 0.00000001225 65.0
HFD1_k127_5239543_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 381.0
HFD1_k127_5239543_4 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 369.0
HFD1_k127_5239543_5 4Fe-4S binding domain K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 335.0
HFD1_k127_5239543_6 4Fe-4S binding domain K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 324.0
HFD1_k127_5239543_7 PFAM response regulator receiver K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001572 268.0
HFD1_k127_5239543_8 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
HFD1_k127_5239543_9 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000001699 258.0
HFD1_k127_5404871_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1182.0
HFD1_k127_5404871_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 623.0
HFD1_k127_5404871_10 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001196 263.0
HFD1_k127_5404871_11 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 262.0
HFD1_k127_5404871_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001493 254.0
HFD1_k127_5404871_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000001243 209.0
HFD1_k127_5404871_14 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000000000000000000859 167.0
HFD1_k127_5404871_15 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000000000000005819 165.0
HFD1_k127_5404871_16 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000391 158.0
HFD1_k127_5404871_17 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000005187 152.0
HFD1_k127_5404871_18 Could be involved in septation K06412 - - 0.000000000000000000000000000000001297 134.0
HFD1_k127_5404871_19 RF-1 domain - - - 0.0000000000000000000000000001186 121.0
HFD1_k127_5404871_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 493.0
HFD1_k127_5404871_20 Regulatory protein, FmdB family - - - 0.0000000000000000001405 91.0
HFD1_k127_5404871_21 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000457 55.0
HFD1_k127_5404871_22 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000001054 56.0
HFD1_k127_5404871_24 oxidoreductase activity - - - 0.00004338 53.0
HFD1_k127_5404871_25 - - - - 0.0001739 50.0
HFD1_k127_5404871_26 domain protein - - - 0.0002859 50.0
HFD1_k127_5404871_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 480.0
HFD1_k127_5404871_4 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 439.0
HFD1_k127_5404871_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 404.0
HFD1_k127_5404871_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 347.0
HFD1_k127_5404871_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006312 286.0
HFD1_k127_5404871_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000003309 274.0
HFD1_k127_5404871_9 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006716 262.0
HFD1_k127_5546715_0 Glycogen debranching enzyme - - - 0.0 1564.0
HFD1_k127_5546715_1 Fatty acid cis/trans isomerase (CTI) - - - 0.0 1256.0
HFD1_k127_5546715_10 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 609.0
HFD1_k127_5546715_11 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 605.0
HFD1_k127_5546715_12 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 528.0
HFD1_k127_5546715_13 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 522.0
HFD1_k127_5546715_14 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 518.0
HFD1_k127_5546715_15 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 501.0
HFD1_k127_5546715_16 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 486.0
HFD1_k127_5546715_17 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 458.0
HFD1_k127_5546715_18 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 443.0
HFD1_k127_5546715_19 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 415.0
HFD1_k127_5546715_2 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0 1206.0
HFD1_k127_5546715_20 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 401.0
HFD1_k127_5546715_21 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 373.0
HFD1_k127_5546715_22 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 356.0
HFD1_k127_5546715_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 333.0
HFD1_k127_5546715_24 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 327.0
HFD1_k127_5546715_25 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 321.0
HFD1_k127_5546715_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 302.0
HFD1_k127_5546715_27 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 300.0
HFD1_k127_5546715_28 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 303.0
HFD1_k127_5546715_29 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000596 288.0
HFD1_k127_5546715_3 Sulfatase - - - 1.119e-287 891.0
HFD1_k127_5546715_30 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 283.0
HFD1_k127_5546715_31 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001736 272.0
HFD1_k127_5546715_32 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001707 265.0
HFD1_k127_5546715_33 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005755 263.0
HFD1_k127_5546715_34 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003745 251.0
HFD1_k127_5546715_35 PFAM HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000000004512 235.0
HFD1_k127_5546715_36 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000001863 227.0
HFD1_k127_5546715_37 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000000000000000000000000000000000000000000000000000000000001616 224.0
HFD1_k127_5546715_38 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000471 224.0
HFD1_k127_5546715_39 TspO MBR family protein K05770 - - 0.000000000000000000000000000000000000000000000000000000000002771 212.0
HFD1_k127_5546715_4 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.085e-276 860.0
HFD1_k127_5546715_40 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000004206 226.0
HFD1_k127_5546715_41 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000000000001665 199.0
HFD1_k127_5546715_42 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000002517 196.0
HFD1_k127_5546715_43 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000001078 180.0
HFD1_k127_5546715_44 Cysteine rich repeat - - - 0.0000000000000000000000000000000000000000000002392 171.0
HFD1_k127_5546715_45 protein conserved in bacteria K09793 - - 0.000000000000000000000000000000000000000000003049 171.0
HFD1_k127_5546715_46 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000006404 166.0
HFD1_k127_5546715_47 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000005089 154.0
HFD1_k127_5546715_48 - - - - 0.00000000000000000000000000000000000000006924 163.0
HFD1_k127_5546715_49 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000005935 152.0
HFD1_k127_5546715_5 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 6.115e-267 838.0
HFD1_k127_5546715_50 - - - - 0.00000000000000000000000000000000000005888 147.0
HFD1_k127_5546715_51 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000008877 148.0
HFD1_k127_5546715_52 Ion channel - - - 0.0000000000000000000000000000000002704 140.0
HFD1_k127_5546715_53 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000001936 137.0
HFD1_k127_5546715_54 PFAM CBS domain - - - 0.00000000000000000000000000000001725 134.0
HFD1_k127_5546715_55 4Fe-4S binding domain - - - 0.00000000000000000000000000000004464 137.0
HFD1_k127_5546715_56 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000008916 134.0
HFD1_k127_5546715_57 PFAM Response regulator receiver domain - - - 0.00000000000000000000000005189 112.0
HFD1_k127_5546715_58 Histidine kinase - - - 0.00000000000000000000002004 117.0
HFD1_k127_5546715_59 - - - - 0.0000000000000000000001753 105.0
HFD1_k127_5546715_6 alpha amylase, catalytic region - - - 1.824e-249 777.0
HFD1_k127_5546715_61 electron transfer activity K05337,K17247 - - 0.00000000000000000001176 92.0
HFD1_k127_5546715_64 PFAM ABC transporter K01990,K09695 - - 0.000000000000001861 77.0
HFD1_k127_5546715_65 AhpC/TSA family K03386 - 1.11.1.15 0.000000000000001917 77.0
HFD1_k127_5546715_66 Rhodanese Homology Domain K01011,K01613 - 2.8.1.1,2.8.1.2,4.1.1.65 0.00000000000001725 78.0
HFD1_k127_5546715_67 - - - - 0.00000000000002056 76.0
HFD1_k127_5546715_68 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.0000000000147 70.0
HFD1_k127_5546715_69 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000001391 71.0
HFD1_k127_5546715_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.626e-247 772.0
HFD1_k127_5546715_70 Cupin 2, conserved barrel domain protein - - - 0.0000000002006 66.0
HFD1_k127_5546715_71 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000003452 63.0
HFD1_k127_5546715_72 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000612 63.0
HFD1_k127_5546715_73 amine dehydrogenase activity - - - 0.00000002801 60.0
HFD1_k127_5546715_74 phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.00000005365 56.0
HFD1_k127_5546715_75 His Kinase A (phosphoacceptor) domain - - - 0.00004129 48.0
HFD1_k127_5546715_76 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00006017 53.0
HFD1_k127_5546715_77 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0001062 51.0
HFD1_k127_5546715_78 - - - - 0.000119 49.0
HFD1_k127_5546715_79 rhodanese-related sulfurtransferase - - - 0.0005693 43.0
HFD1_k127_5546715_8 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 2.575e-209 657.0
HFD1_k127_5546715_80 Cytochrome C' - - - 0.0007364 48.0
HFD1_k127_5546715_81 Glucose dehydrogenase C-terminus - - - 0.0008962 48.0
HFD1_k127_5546715_9 Iron-sulfur cluster-binding domain K06871 - - 6.896e-209 656.0
HFD1_k127_5640570_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.395e-276 859.0
HFD1_k127_5640570_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 5.363e-194 614.0
HFD1_k127_5640570_10 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 362.0
HFD1_k127_5640570_11 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 312.0
HFD1_k127_5640570_12 PFAM glycosyl transferase, family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 316.0
HFD1_k127_5640570_13 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 303.0
HFD1_k127_5640570_14 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005277 270.0
HFD1_k127_5640570_15 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001703 267.0
HFD1_k127_5640570_16 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000393 248.0
HFD1_k127_5640570_17 molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000000000000005521 220.0
HFD1_k127_5640570_18 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000008844 225.0
HFD1_k127_5640570_19 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000005243 220.0
HFD1_k127_5640570_2 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 580.0
HFD1_k127_5640570_20 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000006704 199.0
HFD1_k127_5640570_21 helix_turn_helix, cAMP Regulatory protein - - - 0.00000000000000000000000000000000000000000000000000004578 196.0
HFD1_k127_5640570_22 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000001405 174.0
HFD1_k127_5640570_23 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000002727 166.0
HFD1_k127_5640570_24 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000000000004511 162.0
HFD1_k127_5640570_25 Yip1 domain - - - 0.000000000000000000000000000000001223 140.0
HFD1_k127_5640570_26 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000002962 120.0
HFD1_k127_5640570_27 Roadblock/LC7 domain - - - 0.00000000000000000000000007145 111.0
HFD1_k127_5640570_28 helix_turn_helix, mercury resistance - - - 0.0000000000000000000001143 99.0
HFD1_k127_5640570_29 - - - - 0.0000000000000000189 87.0
HFD1_k127_5640570_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 562.0
HFD1_k127_5640570_30 Domain of unknown function (DUF1858) - - - 0.0000000000000001089 81.0
HFD1_k127_5640570_31 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000001112 84.0
HFD1_k127_5640570_32 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.0000000000000248 86.0
HFD1_k127_5640570_33 sodium-dependent phosphate transmembrane transporter activity - - - 0.0000000000006127 77.0
HFD1_k127_5640570_34 Belongs to the UPF0296 family K09777 - - 0.000000000008049 69.0
HFD1_k127_5640570_35 cheY-homologous receiver domain - - - 0.000000002223 60.0
HFD1_k127_5640570_36 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000005661 60.0
HFD1_k127_5640570_37 Protein of unknown function (DUF2752) - - - 0.00000009213 59.0
HFD1_k127_5640570_38 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000001691 51.0
HFD1_k127_5640570_4 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 552.0
HFD1_k127_5640570_5 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 454.0
HFD1_k127_5640570_6 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 411.0
HFD1_k127_5640570_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 381.0
HFD1_k127_5640570_8 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 379.0
HFD1_k127_5640570_9 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 375.0
HFD1_k127_5694105_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.394e-314 993.0
HFD1_k127_5694105_1 fibronectin type III domain protein K06882 - - 2.92e-205 685.0
HFD1_k127_5694105_10 auxin-activated signaling pathway K07088 - - 0.0000000000000000000000000000000000000000000002855 177.0
HFD1_k127_5694105_11 Enoyl-CoA hydratase/isomerase K13767 - 4.2.1.17 0.00000000000000000000000000000000000000000003515 169.0
HFD1_k127_5694105_12 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000000003253 130.0
HFD1_k127_5694105_13 Rhodanese domain protein - - - 0.000000000000000000004211 96.0
HFD1_k127_5694105_14 DNA-directed DNA polymerase activity - - - 0.0000000000000001603 94.0
HFD1_k127_5694105_15 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000001683 81.0
HFD1_k127_5694105_16 Protein of unknown function (DUF2892) - - - 0.00000000000005541 75.0
HFD1_k127_5694105_17 Zinc ribbon domain - - - 0.00000002709 57.0
HFD1_k127_5694105_18 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000006094 66.0
HFD1_k127_5694105_19 - - - - 0.000001053 58.0
HFD1_k127_5694105_2 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 588.0
HFD1_k127_5694105_20 PFAM type II secretion system protein E K02652 - - 0.00004167 49.0
HFD1_k127_5694105_21 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0005371 47.0
HFD1_k127_5694105_22 - - - - 0.0008835 45.0
HFD1_k127_5694105_3 Major Facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 542.0
HFD1_k127_5694105_4 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 468.0
HFD1_k127_5694105_5 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 406.0
HFD1_k127_5694105_6 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000198 273.0
HFD1_k127_5694105_7 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000001663 184.0
HFD1_k127_5694105_8 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000003383 186.0
HFD1_k127_5694105_9 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000004287 190.0
HFD1_k127_587643_0 Endopeptidase La K04076 - 3.4.21.53 3.59e-236 756.0
HFD1_k127_587643_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 451.0
HFD1_k127_587643_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 377.0
HFD1_k127_587643_3 PFAM MltA K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 337.0
HFD1_k127_587643_4 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000003182 224.0
HFD1_k127_587643_6 Cold shock K03704 - - 0.00000000000000000000001876 101.0
HFD1_k127_587643_7 COG3245 Cytochrome c5 K02277 - 1.9.3.1 0.0000000000000000000789 94.0
HFD1_k127_5945651_0 transporter antisigma-factor antagonist STAS K03321 - - 1.137e-221 702.0
HFD1_k127_5945651_1 response regulator, receiver K01338 - 3.4.21.53 4.202e-213 681.0
HFD1_k127_5945651_10 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 428.0
HFD1_k127_5945651_11 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 429.0
HFD1_k127_5945651_12 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 434.0
HFD1_k127_5945651_13 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 443.0
HFD1_k127_5945651_14 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 419.0
HFD1_k127_5945651_15 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 404.0
HFD1_k127_5945651_16 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 411.0
HFD1_k127_5945651_17 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 409.0
HFD1_k127_5945651_18 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 408.0
HFD1_k127_5945651_19 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 388.0
HFD1_k127_5945651_2 Sigma-54 interaction domain - - - 8.098e-211 664.0
HFD1_k127_5945651_20 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 362.0
HFD1_k127_5945651_21 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 334.0
HFD1_k127_5945651_22 COG0210 Superfamily I DNA and RNA helicases K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 349.0
HFD1_k127_5945651_23 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 323.0
HFD1_k127_5945651_24 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 316.0
HFD1_k127_5945651_25 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 320.0
HFD1_k127_5945651_26 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 305.0
HFD1_k127_5945651_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 301.0
HFD1_k127_5945651_28 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 286.0
HFD1_k127_5945651_29 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 283.0
HFD1_k127_5945651_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 571.0
HFD1_k127_5945651_30 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001624 258.0
HFD1_k127_5945651_31 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002219 257.0
HFD1_k127_5945651_32 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008022 265.0
HFD1_k127_5945651_33 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002824 254.0
HFD1_k127_5945651_34 membrane organization K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003545 259.0
HFD1_k127_5945651_35 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001955 241.0
HFD1_k127_5945651_36 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000001075 241.0
HFD1_k127_5945651_37 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001194 239.0
HFD1_k127_5945651_38 Phosphomethylpyrimidine kinase K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000002264 224.0
HFD1_k127_5945651_39 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000006492 231.0
HFD1_k127_5945651_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 569.0
HFD1_k127_5945651_40 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000006035 218.0
HFD1_k127_5945651_41 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000007724 215.0
HFD1_k127_5945651_42 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000000000000001139 212.0
HFD1_k127_5945651_43 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000002012 215.0
HFD1_k127_5945651_44 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000005839 204.0
HFD1_k127_5945651_45 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000004862 202.0
HFD1_k127_5945651_46 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000294 203.0
HFD1_k127_5945651_47 CGGC - - - 0.0000000000000000000000000000000000000000000000000000008006 196.0
HFD1_k127_5945651_48 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000001877 196.0
HFD1_k127_5945651_49 monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000003374 191.0
HFD1_k127_5945651_5 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 601.0
HFD1_k127_5945651_50 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000000000175 192.0
HFD1_k127_5945651_51 COG3857 ATP-dependent nuclease, subunit B K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000001982 209.0
HFD1_k127_5945651_52 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000002406 191.0
HFD1_k127_5945651_53 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000003905 194.0
HFD1_k127_5945651_54 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000003701 183.0
HFD1_k127_5945651_55 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000479 182.0
HFD1_k127_5945651_56 COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000005759 179.0
HFD1_k127_5945651_57 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000003727 175.0
HFD1_k127_5945651_58 denitrification pathway - - - 0.0000000000000000000000000000000000000000000001085 181.0
HFD1_k127_5945651_59 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000001345 160.0
HFD1_k127_5945651_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 558.0
HFD1_k127_5945651_60 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000004982 164.0
HFD1_k127_5945651_61 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000002168 156.0
HFD1_k127_5945651_62 domain, Protein K02674 - - 0.000000000000000000000000000000000009876 152.0
HFD1_k127_5945651_63 Thioredoxin-like - - - 0.000000000000000000000000000000002849 138.0
HFD1_k127_5945651_64 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000001776 134.0
HFD1_k127_5945651_65 transposase, IS891 IS1136 IS1341 family K07496 - - 0.000000000000000000000000000006658 121.0
HFD1_k127_5945651_67 - - - - 0.0000000000000000006871 88.0
HFD1_k127_5945651_68 Acetyltransferase (GNAT) domain - - - 0.0000000000000004283 85.0
HFD1_k127_5945651_7 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 519.0
HFD1_k127_5945651_70 - - - - 0.00000000000138 74.0
HFD1_k127_5945651_71 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000001636 70.0
HFD1_k127_5945651_73 ThiS family - - - 0.0000000003843 64.0
HFD1_k127_5945651_74 - - - - 0.000000007377 62.0
HFD1_k127_5945651_75 NosL K19342 - - 0.00000004132 61.0
HFD1_k127_5945651_76 - - - - 0.000001308 57.0
HFD1_k127_5945651_77 PFAM UspA domain protein K06149 - - 0.000001777 56.0
HFD1_k127_5945651_78 translation initiation factor activity K03646 - - 0.000003276 55.0
HFD1_k127_5945651_8 membrane protein, terc K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 507.0
HFD1_k127_5945651_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 449.0
HFD1_k127_6095779_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 561.0
HFD1_k127_635457_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1683.0
HFD1_k127_635457_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 2.293e-236 748.0
HFD1_k127_635457_10 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 337.0
HFD1_k127_635457_11 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 325.0
HFD1_k127_635457_12 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 311.0
HFD1_k127_635457_13 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 318.0
HFD1_k127_635457_14 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 294.0
HFD1_k127_635457_15 Lytic transglycolase K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007638 270.0
HFD1_k127_635457_16 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004035 263.0
HFD1_k127_635457_17 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004305 273.0
HFD1_k127_635457_18 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000462 273.0
HFD1_k127_635457_19 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008594 250.0
HFD1_k127_635457_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.551e-215 683.0
HFD1_k127_635457_20 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003258 252.0
HFD1_k127_635457_21 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000008522 211.0
HFD1_k127_635457_22 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000003104 197.0
HFD1_k127_635457_23 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000002748 186.0
HFD1_k127_635457_24 peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000001613 177.0
HFD1_k127_635457_25 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000000007533 177.0
HFD1_k127_635457_26 TIGRFAM iron-sulfur cluster binding protein - - - 0.000000000000000000000000000000000000000000001635 172.0
HFD1_k127_635457_27 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000005345 162.0
HFD1_k127_635457_28 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000001142 156.0
HFD1_k127_635457_29 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.00000000000000000000000000000002112 139.0
HFD1_k127_635457_3 Bacterial transcriptional activator domain - - - 9.83e-198 656.0
HFD1_k127_635457_30 PFAM Stress responsive alpha-beta barrel domain protein - - - 0.00000000000000000000000000000235 122.0
HFD1_k127_635457_31 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000005328 117.0
HFD1_k127_635457_32 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000003736 102.0
HFD1_k127_635457_33 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000011 107.0
HFD1_k127_635457_35 - - - - 0.00000000000000006966 85.0
HFD1_k127_635457_36 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.000000000002762 72.0
HFD1_k127_635457_37 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000002292 57.0
HFD1_k127_635457_38 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000007611 51.0
HFD1_k127_635457_39 cheY-homologous receiver domain - - - 0.00002144 51.0
HFD1_k127_635457_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 565.0
HFD1_k127_635457_40 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00006689 49.0
HFD1_k127_635457_5 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 443.0
HFD1_k127_635457_6 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 429.0
HFD1_k127_635457_7 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 377.0
HFD1_k127_635457_8 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 347.0
HFD1_k127_635457_9 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 333.0
HFD1_k127_6480245_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1202.0
HFD1_k127_6480245_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.666e-211 675.0
HFD1_k127_6480245_10 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004625 240.0
HFD1_k127_6480245_11 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000003708 244.0
HFD1_k127_6480245_12 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000005324 238.0
HFD1_k127_6480245_13 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000009231 231.0
HFD1_k127_6480245_14 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000003716 143.0
HFD1_k127_6480245_15 Universal stress protein family - - - 0.000000000000000000000000000000000001189 143.0
HFD1_k127_6480245_17 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000003545 128.0
HFD1_k127_6480245_18 - - - - 0.0000000000000000000002375 105.0
HFD1_k127_6480245_19 Cysteine-rich small domain K07162 - - 0.0000000000000000000007656 96.0
HFD1_k127_6480245_2 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 589.0
HFD1_k127_6480245_20 cysteine-type peptidase activity - - - 0.00000000000000000001878 106.0
HFD1_k127_6480245_21 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000002913 82.0
HFD1_k127_6480245_22 Transposase K07496 - - 0.0000817 47.0
HFD1_k127_6480245_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 533.0
HFD1_k127_6480245_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 512.0
HFD1_k127_6480245_5 Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 450.0
HFD1_k127_6480245_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 448.0
HFD1_k127_6480245_7 Alpha/beta hydrolase family K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 411.0
HFD1_k127_6480245_8 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 321.0
HFD1_k127_6480245_9 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005107 284.0
HFD1_k127_6589938_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 620.0
HFD1_k127_6589938_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 547.0
HFD1_k127_6589938_2 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 462.0
HFD1_k127_6589938_3 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 370.0
HFD1_k127_6589938_4 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 351.0
HFD1_k127_6623603_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.208e-243 759.0
HFD1_k127_6623603_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 352.0
HFD1_k127_6623603_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000018 163.0
HFD1_k127_6623603_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000001973 109.0
HFD1_k127_6623603_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000004566 92.0
HFD1_k127_6623603_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000002494 72.0
HFD1_k127_6630289_0 GTP-binding protein TypA K06207 - - 3.047e-262 819.0
HFD1_k127_6630289_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 5.216e-218 690.0
HFD1_k127_6630289_10 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 529.0
HFD1_k127_6630289_11 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 528.0
HFD1_k127_6630289_12 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 481.0
HFD1_k127_6630289_13 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 465.0
HFD1_k127_6630289_14 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 454.0
HFD1_k127_6630289_15 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 425.0
HFD1_k127_6630289_16 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 392.0
HFD1_k127_6630289_17 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 389.0
HFD1_k127_6630289_18 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 391.0
HFD1_k127_6630289_19 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 392.0
HFD1_k127_6630289_2 4Fe-4S binding domain - - - 2.636e-217 686.0
HFD1_k127_6630289_20 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 385.0
HFD1_k127_6630289_21 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 386.0
HFD1_k127_6630289_22 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 379.0
HFD1_k127_6630289_23 Protein of unknown function DUF111 K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 373.0
HFD1_k127_6630289_24 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 347.0
HFD1_k127_6630289_25 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
HFD1_k127_6630289_26 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 304.0
HFD1_k127_6630289_27 Glycosyl transferases, related to UDP-glucuronosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 314.0
HFD1_k127_6630289_28 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 303.0
HFD1_k127_6630289_29 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 295.0
HFD1_k127_6630289_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.617e-211 671.0
HFD1_k127_6630289_30 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 302.0
HFD1_k127_6630289_31 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000065 274.0
HFD1_k127_6630289_32 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 269.0
HFD1_k127_6630289_33 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000002654 269.0
HFD1_k127_6630289_34 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003364 259.0
HFD1_k127_6630289_35 Pyridoxamine 5'-phosphate oxidase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000001849 244.0
HFD1_k127_6630289_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002571 241.0
HFD1_k127_6630289_37 phosphoribosylanthranilate isomerase activity K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000656 225.0
HFD1_k127_6630289_38 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000002526 226.0
HFD1_k127_6630289_39 protein conserved in bacteria K09936 - - 0.00000000000000000000000000000000000000000000000000000000000005425 216.0
HFD1_k127_6630289_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.545e-203 639.0
HFD1_k127_6630289_40 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000008845 208.0
HFD1_k127_6630289_41 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000001137 173.0
HFD1_k127_6630289_42 pilus organization K07346 - - 0.00000000000000000000000000000000000000000001586 173.0
HFD1_k127_6630289_43 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.00000000000000000000000000000000000000000005797 173.0
HFD1_k127_6630289_44 2'-5' RNA ligase superfamily - - - 0.0000000000000000000000000000000000000000003819 167.0
HFD1_k127_6630289_45 - - - - 0.000000000000000000000000000000000000000003916 158.0
HFD1_k127_6630289_46 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000005588 148.0
HFD1_k127_6630289_47 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000002257 153.0
HFD1_k127_6630289_48 GGDEF domain - - - 0.0000000000000000000000000000000001254 151.0
HFD1_k127_6630289_49 - K07275 - - 0.0000000000000000000000000000002557 130.0
HFD1_k127_6630289_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 594.0
HFD1_k127_6630289_50 Lysin motif - - - 0.000000000000000000000000956 118.0
HFD1_k127_6630289_51 MarC family integral membrane protein K05595 - - 0.00000000000000000004149 92.0
HFD1_k127_6630289_52 - - - - 0.000000000000000001135 88.0
HFD1_k127_6630289_53 Protein of unknown function (DUF2905) - - - 0.000000000000000003852 86.0
HFD1_k127_6630289_54 Rhodanese Homology Domain - - - 0.0000000000000001724 83.0
HFD1_k127_6630289_55 - - - - 0.00000000000006062 83.0
HFD1_k127_6630289_56 PrcB C-terminal - - - 0.0000000000005259 76.0
HFD1_k127_6630289_57 Putative Ig domain - - - 0.000000000006832 77.0
HFD1_k127_6630289_58 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000003635 64.0
HFD1_k127_6630289_59 SnoaL-like domain - - - 0.0001514 48.0
HFD1_k127_6630289_6 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 602.0
HFD1_k127_6630289_60 Endonuclease containing a URI domain K07461 - - 0.0002323 46.0
HFD1_k127_6630289_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 578.0
HFD1_k127_6630289_8 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 560.0
HFD1_k127_6630289_9 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 527.0
HFD1_k127_6683670_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 298.0
HFD1_k127_6683670_1 PhoQ Sensor - - - 0.0000000000000000000000000000002043 129.0
HFD1_k127_6683670_2 response regulator, receiver - - - 0.000000000000979 77.0
HFD1_k127_6683670_3 Histidine kinase - - - 0.00000000002698 74.0
HFD1_k127_6683670_4 His Kinase A (phosphoacceptor) domain - - - 0.000000001313 68.0
HFD1_k127_6683670_5 Pfam:DUF461 K09796 - - 0.0002651 49.0
HFD1_k127_6683670_6 PilZ domain - - - 0.0007303 48.0
HFD1_k127_6712494_0 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 468.0
HFD1_k127_6712494_1 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 378.0
HFD1_k127_6712494_2 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009352 274.0
HFD1_k127_6712494_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000291 180.0
HFD1_k127_6712494_4 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000503 112.0
HFD1_k127_6712494_5 antisigma factor binding K04749 - - 0.0000000000000005143 84.0
HFD1_k127_6735138_0 FAD binding domain K00394 - 1.8.99.2 0.0 1063.0
HFD1_k127_6735138_1 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 580.0
HFD1_k127_6735138_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 321.0
HFD1_k127_6735138_11 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 315.0
HFD1_k127_6735138_12 RNA pseudouridylate synthase K06175 - 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 303.0
HFD1_k127_6735138_13 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001559 300.0
HFD1_k127_6735138_14 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009215 255.0
HFD1_k127_6735138_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002182 255.0
HFD1_k127_6735138_16 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000003028 243.0
HFD1_k127_6735138_17 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006828 251.0
HFD1_k127_6735138_18 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000005852 228.0
HFD1_k127_6735138_19 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001447 235.0
HFD1_k127_6735138_2 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 534.0
HFD1_k127_6735138_20 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000001529 211.0
HFD1_k127_6735138_21 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000001096 196.0
HFD1_k127_6735138_22 HD domain - - - 0.000000000000000000000000000000000000000000000000000006786 205.0
HFD1_k127_6735138_23 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000002234 193.0
HFD1_k127_6735138_24 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000003358 182.0
HFD1_k127_6735138_25 PFAM Cupin - - - 0.00000000000000000000000000000000000000000000007072 171.0
HFD1_k127_6735138_26 Phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000001154 181.0
HFD1_k127_6735138_27 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000612 135.0
HFD1_k127_6735138_28 Diguanylate cyclase - - - 0.000000000000000000000000000807 130.0
HFD1_k127_6735138_29 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000001156 109.0
HFD1_k127_6735138_3 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 447.0
HFD1_k127_6735138_30 SMART Cold shock protein K03704 - - 0.0000000000000000000000004689 107.0
HFD1_k127_6735138_31 PFAM Forkhead-associated protein - - - 0.0000000000000000000004761 106.0
HFD1_k127_6735138_32 - - - - 0.0000000000000001071 84.0
HFD1_k127_6735138_33 START domain - - - 0.00000000000005348 82.0
HFD1_k127_6735138_34 histone H2A K63-linked ubiquitination K03466 - - 0.00000000004973 68.0
HFD1_k127_6735138_35 UDP-3-O-acyl N-acetylglycosamine deacetylase K16363 - 3.5.1.108,4.2.1.59 0.00000001625 63.0
HFD1_k127_6735138_36 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000001952 55.0
HFD1_k127_6735138_37 PFAM Cytochrome C - - - 0.00004651 54.0
HFD1_k127_6735138_38 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.00005523 56.0
HFD1_k127_6735138_39 FHA domain protein - - - 0.00006123 56.0
HFD1_k127_6735138_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 410.0
HFD1_k127_6735138_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 407.0
HFD1_k127_6735138_6 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 391.0
HFD1_k127_6735138_7 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 354.0
HFD1_k127_6735138_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 352.0
HFD1_k127_6735138_9 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 328.0
HFD1_k127_690072_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 7.365e-272 860.0
HFD1_k127_690072_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.561e-235 744.0
HFD1_k127_690072_10 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 506.0
HFD1_k127_690072_11 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 512.0
HFD1_k127_690072_12 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 507.0
HFD1_k127_690072_13 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 482.0
HFD1_k127_690072_14 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 469.0
HFD1_k127_690072_15 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 432.0
HFD1_k127_690072_16 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 428.0
HFD1_k127_690072_17 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 433.0
HFD1_k127_690072_18 PFAM ABC transporter related K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 391.0
HFD1_k127_690072_19 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 390.0
HFD1_k127_690072_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.964e-221 697.0
HFD1_k127_690072_20 Cys Met metabolism K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 392.0
HFD1_k127_690072_21 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 380.0
HFD1_k127_690072_22 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 376.0
HFD1_k127_690072_23 Lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 354.0
HFD1_k127_690072_24 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 336.0
HFD1_k127_690072_25 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 310.0
HFD1_k127_690072_26 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 302.0
HFD1_k127_690072_27 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 286.0
HFD1_k127_690072_28 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 290.0
HFD1_k127_690072_29 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001155 264.0
HFD1_k127_690072_3 Elongator protein 3, MiaB family, Radical SAM - - - 4.576e-210 664.0
HFD1_k127_690072_30 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002151 262.0
HFD1_k127_690072_31 cog0421, spermidine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000764 259.0
HFD1_k127_690072_32 PFAM Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000993 265.0
HFD1_k127_690072_33 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002155 251.0
HFD1_k127_690072_34 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001048 246.0
HFD1_k127_690072_35 ATP cone domain K07738 - - 0.0000000000000000000000000000000000000000000000000000000007629 206.0
HFD1_k127_690072_36 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000001528 213.0
HFD1_k127_690072_37 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000377 199.0
HFD1_k127_690072_38 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000001493 192.0
HFD1_k127_690072_39 PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000001805 201.0
HFD1_k127_690072_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.851e-200 634.0
HFD1_k127_690072_40 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000005773 187.0
HFD1_k127_690072_41 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000001205 191.0
HFD1_k127_690072_42 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000212 185.0
HFD1_k127_690072_43 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000000000000000005431 182.0
HFD1_k127_690072_44 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000000000000000648 173.0
HFD1_k127_690072_45 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000001345 162.0
HFD1_k127_690072_46 peroxiredoxin, OsmC subfamily K04063 - - 0.0000000000000000000000000000000000000001241 154.0
HFD1_k127_690072_47 - K07112 - - 0.000000000000000000000000000000000000001109 157.0
HFD1_k127_690072_48 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000133 146.0
HFD1_k127_690072_49 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000165 137.0
HFD1_k127_690072_5 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 574.0
HFD1_k127_690072_50 - K07112 - - 0.0000000000000000000000000000002916 130.0
HFD1_k127_690072_51 Domain of unknown function (DUF386) - - - 0.000000000000000000000000000181 119.0
HFD1_k127_690072_52 SURF4 family K15977 - - 0.000000000000000000000000005719 114.0
HFD1_k127_690072_53 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000004638 106.0
HFD1_k127_690072_54 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000003255 98.0
HFD1_k127_690072_55 Belongs to the UPF0250 family K09158 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000003835 89.0
HFD1_k127_690072_56 Tetratricopeptide repeat - - - 0.000000000000000006473 91.0
HFD1_k127_690072_57 Domain of unknown function (DUF4388) - - - 0.000000000000000008883 98.0
HFD1_k127_690072_58 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000006242 89.0
HFD1_k127_690072_59 2Fe-2S -binding domain K13483 - - 0.0000000000001161 76.0
HFD1_k127_690072_6 helicase superfamily c-terminal domain K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 586.0
HFD1_k127_690072_60 TIGRFAM regulatory protein, FmdB - - - 0.000000000004622 69.0
HFD1_k127_690072_61 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000000000006114 69.0
HFD1_k127_690072_62 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.000000000006502 72.0
HFD1_k127_690072_63 homolog subfamily A member 3 K09504 GO:0000002,GO:0000122,GO:0001775,GO:0001776,GO:0001932,GO:0001933,GO:0001941,GO:0001959,GO:0001960,GO:0002119,GO:0002164,GO:0002260,GO:0002376,GO:0002520,GO:0002521,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0005102,GO:0005113,GO:0005126,GO:0005133,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006355,GO:0006357,GO:0006457,GO:0006469,GO:0006725,GO:0006807,GO:0006915,GO:0006919,GO:0006924,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007264,GO:0007275,GO:0007528,GO:0007568,GO:0007569,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008285,GO:0009058,GO:0009059,GO:0009295,GO:0009790,GO:0009791,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010556,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0010950,GO:0010951,GO:0010952,GO:0012501,GO:0016020,GO:0016043,GO:0019219,GO:0019220,GO:0019222,GO:0019897,GO:0019898,GO:0019899,GO:0019900,GO:0019901,GO:0022407,GO:0022409,GO:0023051,GO:0023052,GO:0023057,GO:0030097,GO:0030098,GO:0030154,GO:0030155,GO:0030162,GO:0030217,GO:0030234,GO:0030544,GO:0030695,GO:0030971,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031347,GO:0031348,GO:0031396,GO:0031398,GO:0031399,GO:0031400,GO:0031401,GO:0031594,GO:0031647,GO:0031974,GO:0032042,GO:0032088,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032944,GO:0032946,GO:0033036,GO:0033077,GO:0033673,GO:0034097,GO:0034341,GO:0034613,GO:0034641,GO:0034645,GO:0035556,GO:0042102,GO:0042110,GO:0042127,GO:0042129,GO:0042221,GO:0042325,GO:0042326,GO:0042592,GO:0042645,GO:0042981,GO:0043029,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043113,GO:0043122,GO:0043124,GO:0043154,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043280,GO:0043281,GO:0043433,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044464,GO:0045087,GO:0045088,GO:0045202,GO:0045211,GO:0045321,GO:0045785,GO:0045824,GO:0045859,GO:0045861,GO:0045862,GO:0045892,GO:0045934,GO:0045936,GO:0046483,GO:0046649,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0050670,GO:0050671,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050794,GO:0050808,GO:0050821,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051059,GO:0051082,GO:0051090,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051251,GO:0051252,GO:0051253,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051641,GO:0051668,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060330,GO:0060331,GO:0060334,GO:0060336,GO:0060548,GO:0060589,GO:0060759,GO:0060761,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070227,GO:0070231,GO:0070663,GO:0070665,GO:0070727,GO:0071340,GO:0071704,GO:0071840,GO:0071887,GO:0071944,GO:0072657,GO:0080090,GO:0080134,GO:0090304,GO:0097060,GO:0098590,GO:0098772,GO:0098794,GO:0099173,GO:1901360,GO:1901576,GO:1902531,GO:1902532,GO:1902679,GO:1903037,GO:1903039,GO:1903320,GO:1903322,GO:1903506,GO:1903507,GO:1990782,GO:2000112,GO:2000113,GO:2000116,GO:2000117,GO:2001056,GO:2001141 - 0.0000000003359 74.0
HFD1_k127_690072_64 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000606 50.0
HFD1_k127_690072_7 helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 563.0
HFD1_k127_690072_8 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 549.0
HFD1_k127_690072_9 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 514.0
HFD1_k127_7095158_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1091.0
HFD1_k127_7095158_1 Cache domain - - - 2.444e-252 791.0
HFD1_k127_7095158_10 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 382.0
HFD1_k127_7095158_11 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 343.0
HFD1_k127_7095158_12 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 331.0
HFD1_k127_7095158_13 Adenylate kinase, active site lid K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 327.0
HFD1_k127_7095158_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 323.0
HFD1_k127_7095158_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 295.0
HFD1_k127_7095158_16 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 293.0
HFD1_k127_7095158_17 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 299.0
HFD1_k127_7095158_18 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 304.0
HFD1_k127_7095158_19 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
HFD1_k127_7095158_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.553e-237 741.0
HFD1_k127_7095158_20 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002133 269.0
HFD1_k127_7095158_21 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
HFD1_k127_7095158_22 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 274.0
HFD1_k127_7095158_23 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004859 266.0
HFD1_k127_7095158_24 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007434 265.0
HFD1_k127_7095158_25 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001207 254.0
HFD1_k127_7095158_26 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004584 233.0
HFD1_k127_7095158_27 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000003019 228.0
HFD1_k127_7095158_28 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000001271 196.0
HFD1_k127_7095158_29 TPM domain - - - 0.000000000000000000000000000000000000000000000000000005977 197.0
HFD1_k127_7095158_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 2.391e-201 640.0
HFD1_k127_7095158_30 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000002776 216.0
HFD1_k127_7095158_31 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000132 188.0
HFD1_k127_7095158_32 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000003657 205.0
HFD1_k127_7095158_33 Chromate resistance - - - 0.0000000000000000000000000000000000000000000008083 169.0
HFD1_k127_7095158_34 - - - - 0.0000000000000000000000000000000000000000015 160.0
HFD1_k127_7095158_35 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000001573 113.0
HFD1_k127_7095158_36 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000003507 99.0
HFD1_k127_7095158_37 PFAM Extracellular ligand-binding receptor - - - 0.000000000000000000003019 96.0
HFD1_k127_7095158_38 - - - - 0.0000000000000000006671 91.0
HFD1_k127_7095158_39 mRNA catabolic process K18682 - - 0.00000000000000006615 83.0
HFD1_k127_7095158_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 545.0
HFD1_k127_7095158_40 PFAM PASTA domain - - - 0.0000000000000003578 88.0
HFD1_k127_7095158_41 LPP20 lipoprotein - - - 0.0000000000005111 80.0
HFD1_k127_7095158_42 Stringent starvation protein B K09985 - - 0.0000000000006113 76.0
HFD1_k127_7095158_43 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000001129 53.0
HFD1_k127_7095158_44 sequence-specific DNA binding - - - 0.0002533 49.0
HFD1_k127_7095158_5 PFAM FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 531.0
HFD1_k127_7095158_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 505.0
HFD1_k127_7095158_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 486.0
HFD1_k127_7095158_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 421.0
HFD1_k127_7095158_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 392.0
HFD1_k127_7279634_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1159.0
HFD1_k127_7279634_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1147.0
HFD1_k127_7279634_10 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 555.0
HFD1_k127_7279634_11 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 535.0
HFD1_k127_7279634_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 529.0
HFD1_k127_7279634_13 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 521.0
HFD1_k127_7279634_14 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 499.0
HFD1_k127_7279634_15 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 488.0
HFD1_k127_7279634_16 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 491.0
HFD1_k127_7279634_17 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 477.0
HFD1_k127_7279634_18 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 469.0
HFD1_k127_7279634_19 Pyruvate kinase, alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 412.0
HFD1_k127_7279634_2 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1081.0
HFD1_k127_7279634_20 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 377.0
HFD1_k127_7279634_21 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 387.0
HFD1_k127_7279634_22 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 362.0
HFD1_k127_7279634_23 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 347.0
HFD1_k127_7279634_24 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 344.0
HFD1_k127_7279634_25 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 319.0
HFD1_k127_7279634_26 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 310.0
HFD1_k127_7279634_27 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003527 282.0
HFD1_k127_7279634_28 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002467 279.0
HFD1_k127_7279634_29 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002324 282.0
HFD1_k127_7279634_3 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 5.746e-316 974.0
HFD1_k127_7279634_30 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001497 265.0
HFD1_k127_7279634_31 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004873 252.0
HFD1_k127_7279634_32 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003516 273.0
HFD1_k127_7279634_33 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002037 250.0
HFD1_k127_7279634_34 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000001151 246.0
HFD1_k127_7279634_35 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000000000005683 237.0
HFD1_k127_7279634_36 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
HFD1_k127_7279634_37 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002615 207.0
HFD1_k127_7279634_38 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000005124 207.0
HFD1_k127_7279634_39 biopolymer transport protein - - - 0.0000000000000000000000000000000000000000000000000000000009648 205.0
HFD1_k127_7279634_4 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 9.701e-266 833.0
HFD1_k127_7279634_40 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000353 208.0
HFD1_k127_7279634_41 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000008675 207.0
HFD1_k127_7279634_42 - - - - 0.0000000000000000000000000000000000000000000000000000001044 205.0
HFD1_k127_7279634_43 PFAM SEC-C motif K09858 - - 0.0000000000000000000000000000000000000000000000000000001045 199.0
HFD1_k127_7279634_44 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000000005053 195.0
HFD1_k127_7279634_45 Shikimate kinase K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000003951 192.0
HFD1_k127_7279634_46 PFAM Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000002071 189.0
HFD1_k127_7279634_47 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000008542 175.0
HFD1_k127_7279634_48 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000571 182.0
HFD1_k127_7279634_49 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000001357 168.0
HFD1_k127_7279634_5 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 4.628e-250 786.0
HFD1_k127_7279634_50 hmm pf00545 - GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000002536 166.0
HFD1_k127_7279634_51 AMP binding - - - 0.0000000000000000000000000000000000000000003372 170.0
HFD1_k127_7279634_52 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000004691 158.0
HFD1_k127_7279634_53 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000004427 162.0
HFD1_k127_7279634_54 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.0000000000000000000000000000000000001201 153.0
HFD1_k127_7279634_55 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000003744 140.0
HFD1_k127_7279634_56 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000001199 133.0
HFD1_k127_7279634_57 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000001447 134.0
HFD1_k127_7279634_58 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000009056 133.0
HFD1_k127_7279634_59 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000000002688 125.0
HFD1_k127_7279634_6 acetyl-CoA carboxylase, biotin carboxylase K01965 - 6.4.1.3 1.537e-237 743.0
HFD1_k127_7279634_60 PFAM 4Fe-4S binding domain - - - 0.00000000000000000000000000004085 128.0
HFD1_k127_7279634_61 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000001062 120.0
HFD1_k127_7279634_62 lyase activity - - - 0.0000000000000000000000001059 115.0
HFD1_k127_7279634_63 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000006889 108.0
HFD1_k127_7279634_64 Redox-active disulfide protein - - - 0.000000000000000000009382 94.0
HFD1_k127_7279634_65 phosphate regulon transcriptional regulatory protein PhoB K07657,K07659 - - 0.00000000000000000004119 103.0
HFD1_k127_7279634_66 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000001405 91.0
HFD1_k127_7279634_67 RDD family - - - 0.000000000000000000696 93.0
HFD1_k127_7279634_68 3'-5' exonuclease - - - 0.000000000000000001298 88.0
HFD1_k127_7279634_69 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000468 89.0
HFD1_k127_7279634_7 Uncharacterized protein conserved in bacteria (DUF2344) - - - 5.961e-223 718.0
HFD1_k127_7279634_70 - - - - 0.0000000000000001222 91.0
HFD1_k127_7279634_71 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.0000000000000005364 80.0
HFD1_k127_7279634_72 PFAM UbiE COQ5 methyltransferase - - - 0.00000000000002273 78.0
HFD1_k127_7279634_73 RibD C-terminal domain - - - 0.0000000000001414 73.0
HFD1_k127_7279634_74 Barstar (barnase inhibitor) K03623 - - 0.0000000000005771 73.0
HFD1_k127_7279634_75 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.0000000000008929 75.0
HFD1_k127_7279634_76 - - - - 0.00000000002985 66.0
HFD1_k127_7279634_77 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000007791 61.0
HFD1_k127_7279634_78 TIGRFAM rod shape-determining protein MreD K03571 - - 0.000001254 58.0
HFD1_k127_7279634_79 RibD C-terminal domain - - - 0.0000418 49.0
HFD1_k127_7279634_8 DNA polymerase K02347 - - 3.92e-222 704.0
HFD1_k127_7279634_80 Transposase - - - 0.0002197 47.0
HFD1_k127_7279634_82 3'-5' exonuclease - - - 0.0006963 48.0
HFD1_k127_7279634_9 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 604.0
HFD1_k127_7293972_0 Bacterial protein of unknown function (DUF853) K06915 - - 2.277e-214 675.0
HFD1_k127_7293972_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 603.0
HFD1_k127_7293972_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 544.0
HFD1_k127_7293972_11 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 499.0
HFD1_k127_7293972_12 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 497.0
HFD1_k127_7293972_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 486.0
HFD1_k127_7293972_14 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 492.0
HFD1_k127_7293972_15 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 492.0
HFD1_k127_7293972_16 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 468.0
HFD1_k127_7293972_17 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 460.0
HFD1_k127_7293972_18 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 445.0
HFD1_k127_7293972_19 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 445.0
HFD1_k127_7293972_2 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 601.0
HFD1_k127_7293972_20 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 433.0
HFD1_k127_7293972_21 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 433.0
HFD1_k127_7293972_22 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 412.0
HFD1_k127_7293972_23 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 406.0
HFD1_k127_7293972_24 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 407.0
HFD1_k127_7293972_25 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 394.0
HFD1_k127_7293972_26 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 379.0
HFD1_k127_7293972_27 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 378.0
HFD1_k127_7293972_28 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 362.0
HFD1_k127_7293972_29 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
HFD1_k127_7293972_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 591.0
HFD1_k127_7293972_30 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 340.0
HFD1_k127_7293972_31 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 343.0
HFD1_k127_7293972_32 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 345.0
HFD1_k127_7293972_33 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 328.0
HFD1_k127_7293972_34 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 332.0
HFD1_k127_7293972_35 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 327.0
HFD1_k127_7293972_36 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 317.0
HFD1_k127_7293972_37 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 315.0
HFD1_k127_7293972_38 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 305.0
HFD1_k127_7293972_39 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 296.0
HFD1_k127_7293972_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 587.0
HFD1_k127_7293972_40 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 286.0
HFD1_k127_7293972_41 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002447 285.0
HFD1_k127_7293972_42 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003179 279.0
HFD1_k127_7293972_43 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003109 264.0
HFD1_k127_7293972_44 PFAM Stage II sporulation K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 258.0
HFD1_k127_7293972_45 Transglycosylase SLT domain K06381,K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008913 271.0
HFD1_k127_7293972_46 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000002487 233.0
HFD1_k127_7293972_47 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000002242 225.0
HFD1_k127_7293972_48 - - - - 0.00000000000000000000000000000000000000000000000000000000000003598 227.0
HFD1_k127_7293972_49 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000004467 217.0
HFD1_k127_7293972_5 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 584.0
HFD1_k127_7293972_50 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000002981 216.0
HFD1_k127_7293972_51 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000001142 207.0
HFD1_k127_7293972_52 Fe-S iron-sulfur cluster assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000000000272 199.0
HFD1_k127_7293972_53 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000054 199.0
HFD1_k127_7293972_54 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.0000000000000000000000000000000000000000000000000003297 194.0
HFD1_k127_7293972_55 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000008931 183.0
HFD1_k127_7293972_56 - - - - 0.000000000000000000000000000000000000000000000004646 187.0
HFD1_k127_7293972_57 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000001419 177.0
HFD1_k127_7293972_58 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000004302 174.0
HFD1_k127_7293972_59 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000006797 163.0
HFD1_k127_7293972_6 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 579.0
HFD1_k127_7293972_60 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000001285 163.0
HFD1_k127_7293972_61 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000003005 158.0
HFD1_k127_7293972_62 IS605 family ISDdes4 K07496 - - 0.00000000000000000000000000000000000000007271 156.0
HFD1_k127_7293972_63 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000001081 152.0
HFD1_k127_7293972_64 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000001783 156.0
HFD1_k127_7293972_65 system, mannose fructose sorbose family IID component K02796,K02815 - - 0.000000000000000000000000000000000000179 151.0
HFD1_k127_7293972_66 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000002004 150.0
HFD1_k127_7293972_67 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000003042 136.0
HFD1_k127_7293972_68 PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.000000000000000000000000000002072 126.0
HFD1_k127_7293972_69 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.000000000000000000000000000004574 123.0
HFD1_k127_7293972_7 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 576.0
HFD1_k127_7293972_70 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000004621 118.0
HFD1_k127_7293972_71 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000001318 121.0
HFD1_k127_7293972_73 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000004871 116.0
HFD1_k127_7293972_74 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000005362 120.0
HFD1_k127_7293972_75 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000001247 113.0
HFD1_k127_7293972_76 PFAM Cobalt transport protein K02008 - - 0.00000000000000000000000001369 118.0
HFD1_k127_7293972_77 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000308 106.0
HFD1_k127_7293972_78 phosphocarrier protein hpr K08485,K11189 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.000000000000000000000004565 108.0
HFD1_k127_7293972_79 sulfur carrier activity - - - 0.00000000000000000000005779 100.0
HFD1_k127_7293972_8 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 568.0
HFD1_k127_7293972_80 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000002672 100.0
HFD1_k127_7293972_81 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000000003301 98.0
HFD1_k127_7293972_82 PTS system sorbose-specific iic component K02795 - - 0.0000000000000000001033 98.0
HFD1_k127_7293972_83 - - - - 0.000000000000000002284 88.0
HFD1_k127_7293972_84 PFAM 4Fe-4S ferredoxin - - - 0.000000000000000002917 87.0
HFD1_k127_7293972_85 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000001155 79.0
HFD1_k127_7293972_86 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.000000000001548 76.0
HFD1_k127_7293972_87 Putative diguanylate phosphodiesterase - - - 0.000000000002974 79.0
HFD1_k127_7293972_88 - - - - 0.00000000002627 67.0
HFD1_k127_7293972_89 OstA-like protein K09774 - - 0.0000000000503 70.0
HFD1_k127_7293972_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 555.0
HFD1_k127_7293972_90 - - - - 0.0000000001112 64.0
HFD1_k127_7293972_91 Protein conserved in bacteria K11719 - - 0.0000000002202 69.0
HFD1_k127_7293972_92 - - - - 0.00000002535 62.0
HFD1_k127_7293972_93 Tetratricopeptide repeat - - - 0.0000002214 61.0
HFD1_k127_7293972_94 tetratricopeptide repeat - - - 0.00004159 53.0
HFD1_k127_7394037_0 DEAD/H associated K03724 - - 0.0 1569.0
HFD1_k127_7394037_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1273.0
HFD1_k127_7394037_10 FMN binding - - - 4.905e-277 858.0
HFD1_k127_7394037_100 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001792 284.0
HFD1_k127_7394037_101 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005683 281.0
HFD1_k127_7394037_102 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004327 276.0
HFD1_k127_7394037_103 glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003055 267.0
HFD1_k127_7394037_104 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005044 268.0
HFD1_k127_7394037_105 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 267.0
HFD1_k127_7394037_106 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001382 258.0
HFD1_k127_7394037_107 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000019 256.0
HFD1_k127_7394037_108 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007044 256.0
HFD1_k127_7394037_109 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002232 254.0
HFD1_k127_7394037_11 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 4.276e-265 829.0
HFD1_k127_7394037_110 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004815 254.0
HFD1_k127_7394037_111 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006339 254.0
HFD1_k127_7394037_112 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009135 247.0
HFD1_k127_7394037_113 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002469 244.0
HFD1_k127_7394037_114 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001195 239.0
HFD1_k127_7394037_115 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K21030 - 2.7.7.40,2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000001543 234.0
HFD1_k127_7394037_116 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000009946 226.0
HFD1_k127_7394037_117 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000006327 222.0
HFD1_k127_7394037_118 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000007711 219.0
HFD1_k127_7394037_119 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000003042 218.0
HFD1_k127_7394037_12 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.262e-259 811.0
HFD1_k127_7394037_120 sulfur carrier activity - - - 0.000000000000000000000000000000000000000000000000000000003168 206.0
HFD1_k127_7394037_121 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000169 208.0
HFD1_k127_7394037_122 - - - - 0.0000000000000000000000000000000000000000000000000000005119 201.0
HFD1_k127_7394037_123 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000001089 194.0
HFD1_k127_7394037_124 Protein of unknown function (DUF1207) - - - 0.0000000000000000000000000000000000000000000000000000368 198.0
HFD1_k127_7394037_125 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000008563 196.0
HFD1_k127_7394037_126 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000281 192.0
HFD1_k127_7394037_127 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000001897 195.0
HFD1_k127_7394037_128 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000003606 181.0
HFD1_k127_7394037_129 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000002003 181.0
HFD1_k127_7394037_13 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.57e-257 801.0
HFD1_k127_7394037_130 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000001399 181.0
HFD1_k127_7394037_131 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000001242 169.0
HFD1_k127_7394037_132 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000000000000000000000007743 173.0
HFD1_k127_7394037_133 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000001821 176.0
HFD1_k127_7394037_134 - - - - 0.00000000000000000000000000000000000000000004915 167.0
HFD1_k127_7394037_135 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000005894 164.0
HFD1_k127_7394037_136 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000000000000001009 160.0
HFD1_k127_7394037_137 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000003413 165.0
HFD1_k127_7394037_138 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000001079 165.0
HFD1_k127_7394037_139 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000000003707 156.0
HFD1_k127_7394037_14 Haem-binding uptake, Tiki superfamily, ChaN - - - 1.219e-226 736.0
HFD1_k127_7394037_140 methyltransferase - - - 0.00000000000000000000000000000000000000005033 160.0
HFD1_k127_7394037_141 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000001921 152.0
HFD1_k127_7394037_142 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000005851 150.0
HFD1_k127_7394037_143 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000009801 152.0
HFD1_k127_7394037_144 - - - - 0.000000000000000000000000000000000000171 147.0
HFD1_k127_7394037_145 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000005439 151.0
HFD1_k127_7394037_146 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000007032 162.0
HFD1_k127_7394037_147 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.000000000000000000000000000000000001168 148.0
HFD1_k127_7394037_148 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000214 143.0
HFD1_k127_7394037_149 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000001661 141.0
HFD1_k127_7394037_15 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.643e-225 711.0
HFD1_k127_7394037_150 acid phosphatase activity K03651 - 3.1.4.53 0.000000000000000000000000000000001599 142.0
HFD1_k127_7394037_151 Elongator protein 3, MiaB family, Radical SAM K02585 - - 0.000000000000000000000000000000003167 137.0
HFD1_k127_7394037_152 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000453 134.0
HFD1_k127_7394037_153 Nitroreductase family - - - 0.00000000000000000000000000000001069 134.0
HFD1_k127_7394037_154 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000001708 134.0
HFD1_k127_7394037_155 Protein of unknown function (DUF2845) - - - 0.0000000000000000000000000000007277 129.0
HFD1_k127_7394037_156 TIGRFAM MoaD family protein K03636 - - 0.000000000000000000000000000003392 122.0
HFD1_k127_7394037_157 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000006486 124.0
HFD1_k127_7394037_158 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000005473 120.0
HFD1_k127_7394037_159 Glycosyl transferases group 1 - - - 0.00000000000000000000000000007438 129.0
HFD1_k127_7394037_16 Elongation factor Tu domain 2 K02355 - - 2.629e-221 708.0
HFD1_k127_7394037_160 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000003405 123.0
HFD1_k127_7394037_161 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000006425 118.0
HFD1_k127_7394037_162 JAB/MPN domain - - - 0.00000000000000000000000003026 113.0
HFD1_k127_7394037_163 Thioesterase superfamily - - - 0.00000000000000000000000004663 113.0
HFD1_k127_7394037_164 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000000000000001242 111.0
HFD1_k127_7394037_165 Tetratricopeptide repeat - - - 0.0000000000000000000000006447 116.0
HFD1_k127_7394037_166 - - - - 0.000000000000000000000003936 111.0
HFD1_k127_7394037_167 YbbR-like protein - - - 0.000000000000000000000004745 111.0
HFD1_k127_7394037_168 NIL - - - 0.00000000000000000000000646 104.0
HFD1_k127_7394037_169 sulfur carrier activity - - - 0.00000000000000000000008225 102.0
HFD1_k127_7394037_17 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.375e-211 679.0
HFD1_k127_7394037_170 Rhodanese Homology Domain - - - 0.0000000000000000000001334 100.0
HFD1_k127_7394037_171 Phospholipid methyltransferase - - - 0.0000000000000000000005771 110.0
HFD1_k127_7394037_173 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000001394 96.0
HFD1_k127_7394037_174 Helix-turn-helix domain - - - 0.000000000000000000002386 105.0
HFD1_k127_7394037_175 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000000000000000000005414 96.0
HFD1_k127_7394037_176 - - - - 0.000000000000000000006529 95.0
HFD1_k127_7394037_177 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000001564 95.0
HFD1_k127_7394037_178 - - - - 0.0000000000000000002473 96.0
HFD1_k127_7394037_179 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000891 87.0
HFD1_k127_7394037_18 Sigma-54 interaction domain - - - 2.63e-211 674.0
HFD1_k127_7394037_180 - - - - 0.000000000000000005501 85.0
HFD1_k127_7394037_181 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000007291 82.0
HFD1_k127_7394037_182 Response regulator receiver domain K07668 - - 0.0000000000000005467 83.0
HFD1_k127_7394037_184 lyase activity - - - 0.00000000000005248 78.0
HFD1_k127_7394037_185 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.00000000000006696 77.0
HFD1_k127_7394037_186 Cell division protein ZapA K09888 - - 0.000000000001018 71.0
HFD1_k127_7394037_187 - - - - 0.00000000001301 68.0
HFD1_k127_7394037_188 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000002027 72.0
HFD1_k127_7394037_19 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 6.392e-210 670.0
HFD1_k127_7394037_191 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.0000000005228 66.0
HFD1_k127_7394037_192 SNARE associated Golgi protein - - - 0.0000000007944 60.0
HFD1_k127_7394037_193 Uncharacterized integral membrane protein (DUF2301) - - - 0.000000001722 66.0
HFD1_k127_7394037_194 PFAM Radical SAM domain protein K01012 - 2.8.1.6 0.000000003151 59.0
HFD1_k127_7394037_196 Phospholipase_D-nuclease N-terminal - - - 0.00000002245 57.0
HFD1_k127_7394037_197 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000343 53.0
HFD1_k127_7394037_198 Protein of unknown function (DUF1523) - - - 0.00000052 57.0
HFD1_k127_7394037_199 - - - - 0.000001263 61.0
HFD1_k127_7394037_2 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1019.0
HFD1_k127_7394037_20 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.155e-208 661.0
HFD1_k127_7394037_200 PFAM amino acid-binding ACT domain protein - - - 0.000001425 57.0
HFD1_k127_7394037_202 sulfur relay protein TusB DsrH K07237 - - 0.00002454 50.0
HFD1_k127_7394037_203 polygalacturonase activity - - - 0.0001264 55.0
HFD1_k127_7394037_204 - - - - 0.0001428 50.0
HFD1_k127_7394037_205 - K06039,K07092 - - 0.0001926 51.0
HFD1_k127_7394037_206 Cysteine-rich domain - - - 0.0007259 45.0
HFD1_k127_7394037_21 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.119e-199 629.0
HFD1_k127_7394037_22 Aminotransferase class I and II K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 594.0
HFD1_k127_7394037_23 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 599.0
HFD1_k127_7394037_24 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 579.0
HFD1_k127_7394037_25 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 575.0
HFD1_k127_7394037_26 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 577.0
HFD1_k127_7394037_27 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 569.0
HFD1_k127_7394037_28 PFAM nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 562.0
HFD1_k127_7394037_29 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 561.0
HFD1_k127_7394037_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.017e-318 992.0
HFD1_k127_7394037_30 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 563.0
HFD1_k127_7394037_31 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 570.0
HFD1_k127_7394037_32 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 563.0
HFD1_k127_7394037_33 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 550.0
HFD1_k127_7394037_34 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 544.0
HFD1_k127_7394037_35 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 548.0
HFD1_k127_7394037_36 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 536.0
HFD1_k127_7394037_37 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 510.0
HFD1_k127_7394037_38 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 513.0
HFD1_k127_7394037_39 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 514.0
HFD1_k127_7394037_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.124e-299 929.0
HFD1_k127_7394037_40 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 512.0
HFD1_k127_7394037_41 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 506.0
HFD1_k127_7394037_42 ATPase, AAA K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 498.0
HFD1_k127_7394037_43 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 492.0
HFD1_k127_7394037_44 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 491.0
HFD1_k127_7394037_45 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
HFD1_k127_7394037_46 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 471.0
HFD1_k127_7394037_47 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 456.0
HFD1_k127_7394037_48 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 456.0
HFD1_k127_7394037_49 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 465.0
HFD1_k127_7394037_5 4Fe-4S dicluster domain - - - 3.535e-299 923.0
HFD1_k127_7394037_50 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 451.0
HFD1_k127_7394037_51 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 460.0
HFD1_k127_7394037_52 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 444.0
HFD1_k127_7394037_53 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 437.0
HFD1_k127_7394037_54 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 434.0
HFD1_k127_7394037_55 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 437.0
HFD1_k127_7394037_56 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 427.0
HFD1_k127_7394037_57 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 435.0
HFD1_k127_7394037_58 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 425.0
HFD1_k127_7394037_59 glucose sorbosone K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 424.0
HFD1_k127_7394037_6 PFAM ferredoxin-dependent glutamate synthase - - - 1.223e-296 916.0
HFD1_k127_7394037_60 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 416.0
HFD1_k127_7394037_61 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 422.0
HFD1_k127_7394037_62 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 411.0
HFD1_k127_7394037_63 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 425.0
HFD1_k127_7394037_64 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 418.0
HFD1_k127_7394037_65 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 413.0
HFD1_k127_7394037_66 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 400.0
HFD1_k127_7394037_67 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 407.0
HFD1_k127_7394037_68 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 417.0
HFD1_k127_7394037_69 Initiation factor 2 subunit family K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 397.0
HFD1_k127_7394037_7 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 8.296e-295 914.0
HFD1_k127_7394037_70 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 395.0
HFD1_k127_7394037_71 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 394.0
HFD1_k127_7394037_72 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 386.0
HFD1_k127_7394037_73 glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 388.0
HFD1_k127_7394037_74 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 377.0
HFD1_k127_7394037_75 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 373.0
HFD1_k127_7394037_76 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 376.0
HFD1_k127_7394037_77 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 379.0
HFD1_k127_7394037_78 Signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 377.0
HFD1_k127_7394037_79 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 360.0
HFD1_k127_7394037_8 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.241e-292 910.0
HFD1_k127_7394037_80 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 361.0
HFD1_k127_7394037_81 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 354.0
HFD1_k127_7394037_82 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
HFD1_k127_7394037_83 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 340.0
HFD1_k127_7394037_84 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 340.0
HFD1_k127_7394037_85 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 328.0
HFD1_k127_7394037_86 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 325.0
HFD1_k127_7394037_87 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 317.0
HFD1_k127_7394037_88 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 319.0
HFD1_k127_7394037_89 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 322.0
HFD1_k127_7394037_9 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.367e-278 879.0
HFD1_k127_7394037_90 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 319.0
HFD1_k127_7394037_91 DNA polymerase LigD, polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 311.0
HFD1_k127_7394037_92 Glycosyl transferase, family 2 K07011,K13005 - 2.4.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 309.0
HFD1_k127_7394037_93 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 306.0
HFD1_k127_7394037_94 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 299.0
HFD1_k127_7394037_95 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 290.0
HFD1_k127_7394037_96 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 290.0
HFD1_k127_7394037_97 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 284.0
HFD1_k127_7394037_98 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002536 286.0
HFD1_k127_7394037_99 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001039 278.0
HFD1_k127_7656649_0 glutamate synthase alpha subunit domain protein K00265 - 1.4.1.13,1.4.1.14 0.0 1810.0
HFD1_k127_7656649_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002882 271.0
HFD1_k127_7656649_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000000000000000000009194 106.0
HFD1_k127_7656649_3 Response regulator receiver domain - - - 0.000000000002142 68.0
HFD1_k127_7703359_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1099.0
HFD1_k127_7703359_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.563e-284 912.0
HFD1_k127_7703359_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 320.0
HFD1_k127_7703359_11 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 312.0
HFD1_k127_7703359_12 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 301.0
HFD1_k127_7703359_13 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 292.0
HFD1_k127_7703359_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000002599 199.0
HFD1_k127_7703359_15 response regulator K02658 - - 0.0000000000000000000000000000000000000000000000000000001239 211.0
HFD1_k127_7703359_16 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000003857 179.0
HFD1_k127_7703359_17 Smr domain - - - 0.0000000000000000000000000000000000000000003313 166.0
HFD1_k127_7703359_18 - - - - 0.000000000000000000000000000000000000000005297 158.0
HFD1_k127_7703359_19 Twitching motility two-component system response regulator PilH K02658 - - 0.000000000000000000000000000000000000000009189 156.0
HFD1_k127_7703359_2 aconitate hydratase K01681 - 4.2.1.3 2.37e-277 866.0
HFD1_k127_7703359_20 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000001901 160.0
HFD1_k127_7703359_21 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000004225 139.0
HFD1_k127_7703359_22 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000006155 143.0
HFD1_k127_7703359_23 PFAM response regulator receiver - - - 0.0000000000000000000000000000000008356 133.0
HFD1_k127_7703359_24 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000000000000009795 136.0
HFD1_k127_7703359_25 response regulator - - - 0.00000000000000000000000000214 127.0
HFD1_k127_7703359_26 Two component signalling adaptor domain K03408 - - 0.0000000000000002084 85.0
HFD1_k127_7703359_27 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000001198 75.0
HFD1_k127_7703359_28 Major Facilitator Superfamily - - - 0.000001674 49.0
HFD1_k127_7703359_29 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0005335 50.0
HFD1_k127_7703359_3 Sulfatase - - - 1.444e-232 736.0
HFD1_k127_7703359_4 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 561.0
HFD1_k127_7703359_5 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 499.0
HFD1_k127_7703359_6 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K02487,K06596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 475.0
HFD1_k127_7703359_7 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 417.0
HFD1_k127_7703359_8 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 387.0
HFD1_k127_7703359_9 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 369.0
HFD1_k127_7988846_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1534.0
HFD1_k127_7988846_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 8.772e-276 859.0
HFD1_k127_7988846_10 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 485.0
HFD1_k127_7988846_11 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 479.0
HFD1_k127_7988846_12 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 466.0
HFD1_k127_7988846_13 response regulator receiver K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 473.0
HFD1_k127_7988846_14 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 458.0
HFD1_k127_7988846_15 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 439.0
HFD1_k127_7988846_16 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 441.0
HFD1_k127_7988846_17 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 410.0
HFD1_k127_7988846_18 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 420.0
HFD1_k127_7988846_19 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 409.0
HFD1_k127_7988846_2 Domain of unknown function (DUF1957) K16149 - 2.4.1.18 1.553e-252 787.0
HFD1_k127_7988846_20 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 397.0
HFD1_k127_7988846_21 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 388.0
HFD1_k127_7988846_22 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 387.0
HFD1_k127_7988846_23 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 376.0
HFD1_k127_7988846_24 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 366.0
HFD1_k127_7988846_25 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 361.0
HFD1_k127_7988846_26 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 349.0
HFD1_k127_7988846_27 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 349.0
HFD1_k127_7988846_28 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 349.0
HFD1_k127_7988846_29 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 329.0
HFD1_k127_7988846_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.275e-233 738.0
HFD1_k127_7988846_30 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 336.0
HFD1_k127_7988846_31 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 329.0
HFD1_k127_7988846_32 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 321.0
HFD1_k127_7988846_33 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 295.0
HFD1_k127_7988846_34 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 305.0
HFD1_k127_7988846_35 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 297.0
HFD1_k127_7988846_36 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006566 286.0
HFD1_k127_7988846_37 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001813 277.0
HFD1_k127_7988846_38 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004059 257.0
HFD1_k127_7988846_39 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000004296 232.0
HFD1_k127_7988846_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.483e-204 651.0
HFD1_k127_7988846_40 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000001497 248.0
HFD1_k127_7988846_41 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000006127 232.0
HFD1_k127_7988846_42 Cytidylate kinase K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000009424 232.0
HFD1_k127_7988846_43 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000009767 237.0
HFD1_k127_7988846_44 RecF/RecN/SMC N terminal domain K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000002021 231.0
HFD1_k127_7988846_45 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000005122 230.0
HFD1_k127_7988846_46 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000004496 206.0
HFD1_k127_7988846_47 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000002434 202.0
HFD1_k127_7988846_48 metal cluster binding - - - 0.00000000000000000000000000000000000000000000000000004225 194.0
HFD1_k127_7988846_49 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000005184 191.0
HFD1_k127_7988846_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 576.0
HFD1_k127_7988846_50 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000002501 175.0
HFD1_k127_7988846_51 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000002239 172.0
HFD1_k127_7988846_52 low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000001067 162.0
HFD1_k127_7988846_53 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000008793 157.0
HFD1_k127_7988846_54 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000006847 154.0
HFD1_k127_7988846_55 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000003975 154.0
HFD1_k127_7988846_56 Domain of unknown function (DUF4912) K09942 - - 0.0000000000000000000000000000000000007138 152.0
HFD1_k127_7988846_57 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000008376 147.0
HFD1_k127_7988846_58 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000964 143.0
HFD1_k127_7988846_59 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000001013 136.0
HFD1_k127_7988846_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 541.0
HFD1_k127_7988846_60 Domain of unknown function (DUF4253) - - - 0.00000000000000000000000000000001852 134.0
HFD1_k127_7988846_61 - - - - 0.0000000000000000000000000000000582 131.0
HFD1_k127_7988846_62 isopentenyl-diphosphate delta-isomerase activity - - - 0.00000000000000000000000000000007401 133.0
HFD1_k127_7988846_63 - - - - 0.0000000000000000000000000001308 118.0
HFD1_k127_7988846_64 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000165 117.0
HFD1_k127_7988846_65 - - - - 0.000000000000000000000000002361 121.0
HFD1_k127_7988846_66 RNA-binding protein - - - 0.00000000000000000000000001355 113.0
HFD1_k127_7988846_67 metalloendopeptidase activity K03799 - - 0.0000000000000000000000002487 118.0
HFD1_k127_7988846_68 membrane - - - 0.000000000000000000000008838 103.0
HFD1_k127_7988846_69 - - - - 0.00000000000000000001086 95.0
HFD1_k127_7988846_7 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 538.0
HFD1_k127_7988846_70 redox-active disulfide protein 2 - - - 0.0000000000000000002219 91.0
HFD1_k127_7988846_71 deoxyhypusine monooxygenase activity - - - 0.00000000000000005414 89.0
HFD1_k127_7988846_72 Heavy-metal-associated domain - - - 0.00000000000001498 77.0
HFD1_k127_7988846_74 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000008461 70.0
HFD1_k127_7988846_75 protein secretion K03116 - - 0.000000000009959 67.0
HFD1_k127_7988846_76 Domain of unknown function (DUF2703) - - - 0.00000000003045 69.0
HFD1_k127_7988846_77 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000006677 70.0
HFD1_k127_7988846_79 - - - - 0.000002578 57.0
HFD1_k127_7988846_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 500.0
HFD1_k127_7988846_80 Belongs to the HesB IscA family K13628 - - 0.000003356 51.0
HFD1_k127_7988846_81 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.00001654 53.0
HFD1_k127_7988846_9 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 496.0
HFD1_k127_7992194_0 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 369.0
HFD1_k127_7992194_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000005397 250.0
HFD1_k127_7992194_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000003629 223.0
HFD1_k127_7992194_3 Dihydroneopterin aldolase - - - 0.00000000000000000000000000000000000000001862 163.0
HFD1_k127_7992194_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000000000000002324 135.0
HFD1_k127_7992194_5 - - - - 0.0000000000000000000000000000001552 129.0
HFD1_k127_7992194_6 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000007932 105.0
HFD1_k127_7992194_7 Involved in the tonB-independent uptake of proteins - - - 0.00000000004365 66.0
HFD1_k127_7992194_8 helix_turn_helix, mercury resistance - - - 0.00000002909 63.0
HFD1_k127_831005_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 525.0
HFD1_k127_831005_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 456.0
HFD1_k127_831005_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 403.0
HFD1_k127_831005_3 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000002794 147.0
HFD1_k127_831005_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000009566 121.0
HFD1_k127_862984_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 449.0
HFD1_k127_862984_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 286.0
HFD1_k127_862984_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000005242 173.0
HFD1_k127_862984_3 UPF0126 domain - - - 0.000000000000000000000000002596 114.0
HFD1_k127_940766_0 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 336.0
HFD1_k127_940766_1 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000003926 145.0
HFD1_k127_940766_2 response to heat K03668 - - 0.00000000000000009911 87.0
HFD1_k127_948793_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 3e-290 902.0
HFD1_k127_948793_1 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 4.907e-249 786.0
HFD1_k127_948793_10 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 403.0
HFD1_k127_948793_11 belongs to the CobB CobQ family K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 386.0
HFD1_k127_948793_12 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 381.0
HFD1_k127_948793_13 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 379.0
HFD1_k127_948793_14 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 348.0
HFD1_k127_948793_15 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 345.0
HFD1_k127_948793_16 phosphorelay signal transduction system K02535,K13599,K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 321.0
HFD1_k127_948793_17 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 296.0
HFD1_k127_948793_18 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 295.0
HFD1_k127_948793_19 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 292.0
HFD1_k127_948793_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.034e-215 676.0
HFD1_k127_948793_20 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 292.0
HFD1_k127_948793_21 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000003839 213.0
HFD1_k127_948793_22 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000004693 204.0
HFD1_k127_948793_23 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000003783 192.0
HFD1_k127_948793_24 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000005013 194.0
HFD1_k127_948793_25 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000001131 198.0
HFD1_k127_948793_26 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000000002634 175.0
HFD1_k127_948793_27 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000000000000000000000000003318 173.0
HFD1_k127_948793_28 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000001736 169.0
HFD1_k127_948793_29 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000001167 149.0
HFD1_k127_948793_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 571.0
HFD1_k127_948793_30 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000000000000000005081 143.0
HFD1_k127_948793_31 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000001942 144.0
HFD1_k127_948793_32 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000008135 139.0
HFD1_k127_948793_33 Transcriptional - - - 0.0000000000000000000000000000000008518 132.0
HFD1_k127_948793_34 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000002345 120.0
HFD1_k127_948793_37 - - - - 0.0000000000000000000000168 108.0
HFD1_k127_948793_38 Papain-like cysteine protease AvrRpt2 - - - 0.0000000000000000000000611 106.0
HFD1_k127_948793_39 Tetratricopeptide repeat - - - 0.000000000000000000003154 107.0
HFD1_k127_948793_4 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 557.0
HFD1_k127_948793_40 Tetratricopeptide repeat - - - 0.000000000000000000003885 101.0
HFD1_k127_948793_41 TIGRFAM cytochrome C family protein - - - 0.0000000000000000002753 103.0
HFD1_k127_948793_42 FecR protein - - - 0.0000000000000000009158 96.0
HFD1_k127_948793_43 transposase, IS891 IS1136 IS1341 family K07496 - - 0.0000000000000002456 79.0
HFD1_k127_948793_44 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000001066 78.0
HFD1_k127_948793_45 - - - - 0.0000000000002692 75.0
HFD1_k127_948793_47 - - - - 0.00000000007775 68.0
HFD1_k127_948793_48 denitrification pathway K03620 - - 0.0000000003849 72.0
HFD1_k127_948793_49 - - - - 0.0000002088 55.0
HFD1_k127_948793_5 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 475.0
HFD1_k127_948793_50 - - - - 0.0000002439 53.0
HFD1_k127_948793_52 S-layer homology domain - - - 0.00007786 55.0
HFD1_k127_948793_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 481.0
HFD1_k127_948793_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 483.0
HFD1_k127_948793_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 415.0
HFD1_k127_948793_9 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 390.0