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Overview

ID MAG01617
Name HFD1_bin.25
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Eisenbacteria
Class RBG-16-71-46
Order SZUA-252
Family SZUA-252
Genus SZUA-252
Species SZUA-252 sp035716005
Assembly information
Completeness (%) 59.47
Contamination (%) 1.85
GC content (%) 69.0
N50 (bp) 10,806
Genome size (bp) 2,114,316

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1798

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1075997_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.0 1429.0
HFD1_k127_1075997_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 381.0
HFD1_k127_1075997_2 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 359.0
HFD1_k127_1075997_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 310.0
HFD1_k127_1075997_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000521 185.0
HFD1_k127_1075997_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000007399 168.0
HFD1_k127_1075997_6 - - - - 0.0000000000000009716 85.0
HFD1_k127_1075997_7 PFAM Outer membrane efflux protein - - - 0.000000000000001557 90.0
HFD1_k127_1075997_8 polysaccharide catabolic process K01179,K01218 - 3.2.1.4,3.2.1.78 0.00000005368 67.0
HFD1_k127_1103936_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 338.0
HFD1_k127_1103936_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 336.0
HFD1_k127_1103936_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 295.0
HFD1_k127_1103936_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001205 279.0
HFD1_k127_1103936_4 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000003157 241.0
HFD1_k127_1107139_0 Peptidase m28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 453.0
HFD1_k127_1107139_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000004504 193.0
HFD1_k127_1111758_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.737e-220 705.0
HFD1_k127_1111758_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 613.0
HFD1_k127_1111758_10 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000001065 201.0
HFD1_k127_1111758_11 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000005725 210.0
HFD1_k127_1111758_12 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000000000000000008436 182.0
HFD1_k127_1111758_13 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K00627,K01571,K02160 - 2.3.1.12,4.1.1.3 0.000000000000000000000000000000005533 131.0
HFD1_k127_1111758_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000004647 128.0
HFD1_k127_1111758_15 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000002 113.0
HFD1_k127_1111758_16 Protein of unknown function (DUF503) K09764 - - 0.000000000000000148 83.0
HFD1_k127_1111758_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000002041 79.0
HFD1_k127_1111758_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 612.0
HFD1_k127_1111758_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 418.0
HFD1_k127_1111758_4 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 421.0
HFD1_k127_1111758_5 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 299.0
HFD1_k127_1111758_6 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009048 301.0
HFD1_k127_1111758_7 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002524 247.0
HFD1_k127_1111758_8 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000001646 241.0
HFD1_k127_1111758_9 Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000001753 225.0
HFD1_k127_1124640_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1217.0
HFD1_k127_1124640_1 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 6.891e-270 854.0
HFD1_k127_1124640_10 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000002605 70.0
HFD1_k127_1124640_11 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00000001436 58.0
HFD1_k127_1124640_12 cellulose binding - - - 0.00000003681 56.0
HFD1_k127_1124640_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.585e-198 641.0
HFD1_k127_1124640_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 496.0
HFD1_k127_1124640_4 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 326.0
HFD1_k127_1124640_5 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000001292 207.0
HFD1_k127_1124640_6 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000003514 169.0
HFD1_k127_1124640_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000008341 130.0
HFD1_k127_1124640_8 alpha-ribazole phosphatase activity K01834 - 5.4.2.11 0.000000000000000000000000000011 129.0
HFD1_k127_1124640_9 FixH - - - 0.00000000000000000006853 105.0
HFD1_k127_1133480_0 elongation factor G K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 1.132e-214 687.0
HFD1_k127_1133480_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003887 248.0
HFD1_k127_1133480_2 Subtilase family - - - 0.000000000000000000000000000000000000000000002787 179.0
HFD1_k127_1133480_3 - - - - 0.000000000000000000000000000000000006444 147.0
HFD1_k127_1133480_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00004072 57.0
HFD1_k127_1152058_0 Type II/IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 507.0
HFD1_k127_1152058_1 PFAM type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000003044 205.0
HFD1_k127_1152058_2 Type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000005954 202.0
HFD1_k127_1152058_3 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription K03088 - - 0.000000000000000000002362 101.0
HFD1_k127_1152058_4 AAA domain K02282 - - 0.0000009663 61.0
HFD1_k127_1157620_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 401.0
HFD1_k127_1157620_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 313.0
HFD1_k127_1157620_2 lyase activity - - - 0.00000000000000000000000000000000000000003238 173.0
HFD1_k127_1157620_3 AAA domain - - - 0.00000000000000000000001009 117.0
HFD1_k127_1157620_4 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.00000000004645 68.0
HFD1_k127_1171808_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 389.0
HFD1_k127_1171808_1 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 339.0
HFD1_k127_1171808_2 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000321 296.0
HFD1_k127_1171808_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338,K08675 - 3.4.21.53 0.000000000008799 69.0
HFD1_k127_1171808_4 Histidine kinase - - - 0.0001065 55.0
HFD1_k127_1171808_5 Right handed beta helix region - - - 0.0008231 51.0
HFD1_k127_1207772_0 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 338.0
HFD1_k127_1207772_1 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004871 281.0
HFD1_k127_1207772_2 Surface antigen - - - 0.000000000000000000000000000000002178 146.0
HFD1_k127_1207772_3 Domain of unknown function (DUF3943) - - - 0.00000000000000000000001959 116.0
HFD1_k127_1207772_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000003624 101.0
HFD1_k127_1207772_5 - - - - 0.00000000000000000524 90.0
HFD1_k127_1207772_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000009882 60.0
HFD1_k127_1258346_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001194 279.0
HFD1_k127_1258346_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000009621 151.0
HFD1_k127_1258346_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000005339 153.0
HFD1_k127_1258346_3 - - - - 0.00000000000000000000000000000003223 131.0
HFD1_k127_1258346_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0001483 48.0
HFD1_k127_128998_0 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 429.0
HFD1_k127_128998_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 350.0
HFD1_k127_128998_2 - K07164 - - 0.000000000000003484 84.0
HFD1_k127_1290530_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000009471 197.0
HFD1_k127_1290530_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000005888 198.0
HFD1_k127_1290530_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000008077 178.0
HFD1_k127_1290530_3 - - - - 0.000000000000000000000000000000000000001256 161.0
HFD1_k127_1290530_4 Response regulator receiver domain - - - 0.0000000000000000000000000000000008868 134.0
HFD1_k127_1290530_5 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000004349 124.0
HFD1_k127_1290530_6 PFAM protein phosphatase 2C domain protein, response regulator receiver K07315 - 3.1.3.3 0.00000000000000000000000009258 117.0
HFD1_k127_1290530_7 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.00000000000000000000000009973 113.0
HFD1_k127_1290530_8 COG NOG24984 non supervised orthologous group - - - 0.0000001206 65.0
HFD1_k127_1324790_0 Part of a membrane complex involved in electron transport K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 457.0
HFD1_k127_1324790_1 amidase activity K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 415.0
HFD1_k127_1324790_10 Arginase family K01476 - 3.5.3.1 0.000000000000008051 76.0
HFD1_k127_1324790_11 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000008751 74.0
HFD1_k127_1324790_12 electron transfer activity K05337 - - 0.0004867 48.0
HFD1_k127_1324790_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 399.0
HFD1_k127_1324790_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347,K03614 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 323.0
HFD1_k127_1324790_4 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000003904 182.0
HFD1_k127_1324790_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000003278 158.0
HFD1_k127_1324790_6 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000006017 162.0
HFD1_k127_1324790_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000003491 139.0
HFD1_k127_1324790_8 PHP domain protein - - - 0.000000000000000000000000002333 130.0
HFD1_k127_1324790_9 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169,K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0000000000000000000000001638 121.0
HFD1_k127_1345619_0 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 422.0
HFD1_k127_1345619_1 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 398.0
HFD1_k127_1345619_2 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 333.0
HFD1_k127_1345619_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000006499 163.0
HFD1_k127_1362145_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 426.0
HFD1_k127_1362145_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 377.0
HFD1_k127_1362145_2 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 346.0
HFD1_k127_1362145_3 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 316.0
HFD1_k127_1362145_4 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 303.0
HFD1_k127_1368524_0 Malate synthase K01638 - 2.3.3.9 4.616e-221 694.0
HFD1_k127_1368524_1 Isocitrate lyase K01637 - 4.1.3.1 2.964e-202 661.0
HFD1_k127_1368524_10 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000269 277.0
HFD1_k127_1368524_11 Zn-dependent proteases and their inactivated homologs K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001381 298.0
HFD1_k127_1368524_12 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001403 268.0
HFD1_k127_1368524_13 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001793 265.0
HFD1_k127_1368524_14 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005752 250.0
HFD1_k127_1368524_15 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001473 245.0
HFD1_k127_1368524_16 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000007099 236.0
HFD1_k127_1368524_17 Pyridine nucleotide-disulphide oxidoreductase K00384,K03387,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000006593 229.0
HFD1_k127_1368524_18 secreted hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000002031 220.0
HFD1_k127_1368524_19 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000008539 225.0
HFD1_k127_1368524_2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 625.0
HFD1_k127_1368524_20 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000003659 213.0
HFD1_k127_1368524_21 peptidase - - - 0.000000000000000000000000000000000000000000000007761 198.0
HFD1_k127_1368524_22 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000007406 178.0
HFD1_k127_1368524_23 Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000002628 184.0
HFD1_k127_1368524_24 COG1131 ABC-type multidrug transport system, ATPase component K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000511 175.0
HFD1_k127_1368524_25 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000002678 151.0
HFD1_k127_1368524_26 Rhodanese Homology Domain - - - 0.000000000000000000000000000005575 122.0
HFD1_k127_1368524_27 alpha/beta hydrolase fold - - - 0.0000000000000000000000000007681 128.0
HFD1_k127_1368524_28 mutator MutT protein K03574,K03575 - 3.6.1.55 0.000000000000000000000000001037 121.0
HFD1_k127_1368524_29 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000001161 114.0
HFD1_k127_1368524_3 PFAM Cytochrome c assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 566.0
HFD1_k127_1368524_30 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000001259 102.0
HFD1_k127_1368524_31 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000114 93.0
HFD1_k127_1368524_32 Cytochrome c - - - 0.000000000000002789 90.0
HFD1_k127_1368524_33 Radical SAM - - - 0.0000000000004525 82.0
HFD1_k127_1368524_34 subunit of a heme lyase K02200 - - 0.0000000009164 72.0
HFD1_k127_1368524_4 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 558.0
HFD1_k127_1368524_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 377.0
HFD1_k127_1368524_6 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 358.0
HFD1_k127_1368524_7 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 358.0
HFD1_k127_1368524_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 315.0
HFD1_k127_1368524_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 321.0
HFD1_k127_1419576_0 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 599.0
HFD1_k127_1419576_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 401.0
HFD1_k127_1419576_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 303.0
HFD1_k127_1419576_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000004535 259.0
HFD1_k127_1419576_4 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000002727 227.0
HFD1_k127_1419576_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000002692 204.0
HFD1_k127_1419576_6 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000004254 198.0
HFD1_k127_1419576_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.0000000000000000000000000000009476 139.0
HFD1_k127_149548_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 509.0
HFD1_k127_149548_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 535.0
HFD1_k127_149548_10 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000001924 169.0
HFD1_k127_149548_11 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000001948 145.0
HFD1_k127_149548_12 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000000002139 143.0
HFD1_k127_149548_13 Glycine cleavage H-protein - - - 0.000000000000000000000000003373 125.0
HFD1_k127_149548_14 PFAM glycine cleavage H-protein - - - 0.0000000000000002951 88.0
HFD1_k127_149548_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000007552 55.0
HFD1_k127_149548_2 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 527.0
HFD1_k127_149548_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 482.0
HFD1_k127_149548_4 virion core protein (lumpy skin disease virus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 432.0
HFD1_k127_149548_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 360.0
HFD1_k127_149548_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 369.0
HFD1_k127_149548_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 354.0
HFD1_k127_149548_8 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 326.0
HFD1_k127_149548_9 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 319.0
HFD1_k127_1502567_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1033.0
HFD1_k127_1502567_1 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.000000000000000000000000000000000000003046 153.0
HFD1_k127_1502567_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000004235 119.0
HFD1_k127_1511538_0 ABC transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 578.0
HFD1_k127_1511538_1 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000003324 238.0
HFD1_k127_1511538_2 ABC transporter K18893 - - 0.00000000000172 68.0
HFD1_k127_1655678_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 414.0
HFD1_k127_1655678_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 332.0
HFD1_k127_1655678_2 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000865 240.0
HFD1_k127_1655678_3 Belongs to the sigma-70 factor family K02405 - - 0.0000000000000000000000000000000000000000000000000000000003573 214.0
HFD1_k127_1655678_4 Hpt domain - - - 0.0000000000000000000000000000000000000000000000000000004421 221.0
HFD1_k127_1655678_5 HDOD domain - - - 0.000000000000000000000000000000000000000000001667 176.0
HFD1_k127_1655678_6 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000005087 111.0
HFD1_k127_1655678_7 Protein of unknown function (DUF2723) K14340 - - 0.000000000002669 80.0
HFD1_k127_1660915_0 PFAM GlcNAc-PI de-N-acetylase - - - 8.635e-231 741.0
HFD1_k127_1660915_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 590.0
HFD1_k127_1660915_2 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000002904 220.0
HFD1_k127_1660915_3 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000000003977 143.0
HFD1_k127_1671576_0 Evidence 5 No homology to any previously reported sequences K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 343.0
HFD1_k127_1671576_1 Propeptide_C25 - - - 0.00000000000000000000000000000000000000000000000000000000000002155 243.0
HFD1_k127_1671576_2 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000001513 186.0
HFD1_k127_1671576_3 - - - - 0.000000000000000000000000000000000001303 160.0
HFD1_k127_1671576_4 - - - - 0.000000000000001085 88.0
HFD1_k127_1671576_5 - - - - 0.00000000000001852 83.0
HFD1_k127_1671576_6 NHL repeat - - - 0.00003974 55.0
HFD1_k127_1680574_0 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000003405 196.0
HFD1_k127_1680574_2 Peptidase family M13 K07386 - - 0.000000000000000000000000008354 116.0
HFD1_k127_1690641_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 443.0
HFD1_k127_1690641_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 430.0
HFD1_k127_1690641_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 297.0
HFD1_k127_1690641_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001835 247.0
HFD1_k127_1690641_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000006497 148.0
HFD1_k127_1690641_5 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000004125 138.0
HFD1_k127_1690641_6 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000008762 98.0
HFD1_k127_1690641_7 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000001126 87.0
HFD1_k127_1700476_0 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 4.349e-282 881.0
HFD1_k127_1700476_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 471.0
HFD1_k127_1700476_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 299.0
HFD1_k127_1700476_3 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000003764 140.0
HFD1_k127_1700476_4 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000201 153.0
HFD1_k127_1700476_5 Glycosyl hydrolases family 15 - - - 0.0000000000000000000006882 110.0
HFD1_k127_1708496_0 Enolase, C-terminal TIM barrel domain K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 584.0
HFD1_k127_1708496_1 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 443.0
HFD1_k127_1708496_10 Domain of unknown function (DUF4390) - - - 0.00000995 58.0
HFD1_k127_1708496_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 310.0
HFD1_k127_1708496_3 transcription factor binding K02584,K11914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 312.0
HFD1_k127_1708496_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001343 250.0
HFD1_k127_1708496_5 Histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000007205 219.0
HFD1_k127_1708496_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000001348 203.0
HFD1_k127_1708496_7 ECF sigma factor K03088 - - 0.000000000000000000000000000004687 126.0
HFD1_k127_1708496_8 surface antigen - - - 0.000000000000000000000009664 115.0
HFD1_k127_1708496_9 Polymer-forming cytoskeletal - - - 0.000000000258 73.0
HFD1_k127_1709865_0 Oligoendopeptidase f - - - 1.749e-210 676.0
HFD1_k127_1709865_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 7.536e-199 626.0
HFD1_k127_1709865_10 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 337.0
HFD1_k127_1709865_11 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 330.0
HFD1_k127_1709865_12 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 298.0
HFD1_k127_1709865_13 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000565 273.0
HFD1_k127_1709865_14 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000002348 259.0
HFD1_k127_1709865_15 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002874 269.0
HFD1_k127_1709865_16 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000007899 236.0
HFD1_k127_1709865_17 Pfam:PNPOx_C K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000003546 202.0
HFD1_k127_1709865_18 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000009322 214.0
HFD1_k127_1709865_19 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000001459 208.0
HFD1_k127_1709865_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 518.0
HFD1_k127_1709865_20 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000008333 144.0
HFD1_k127_1709865_21 SnoaL-like domain - - - 0.00000000000000000004617 98.0
HFD1_k127_1709865_22 Acetyltransferase (GNAT) domain - - - 0.00000000000000000004762 100.0
HFD1_k127_1709865_23 Pyruvate phosphate dikinase - - - 0.00000000000000003178 96.0
HFD1_k127_1709865_24 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.000000000000007339 89.0
HFD1_k127_1709865_25 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000000000002243 74.0
HFD1_k127_1709865_26 Biotin carboxylase C-terminal domain K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000008079 82.0
HFD1_k127_1709865_27 Outer membrane protein beta-barrel domain - - - 0.000000001251 68.0
HFD1_k127_1709865_28 COG0457 FOG TPR repeat - - - 0.0000004604 62.0
HFD1_k127_1709865_3 Biotin carboxylase C-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 460.0
HFD1_k127_1709865_4 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 410.0
HFD1_k127_1709865_5 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 404.0
HFD1_k127_1709865_6 Domain of unknown function(DUF2779) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 393.0
HFD1_k127_1709865_7 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 362.0
HFD1_k127_1709865_8 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 355.0
HFD1_k127_1709865_9 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 325.0
HFD1_k127_1711949_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 415.0
HFD1_k127_1711949_1 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 349.0
HFD1_k127_1711949_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 321.0
HFD1_k127_1711949_3 Calcineurin-like phosphoesterase K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000132 233.0
HFD1_k127_1711949_4 NUDIX domain - - - 0.00000000000000000000000000000000000000004954 158.0
HFD1_k127_1711949_5 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000746 121.0
HFD1_k127_1711949_6 DinB family - - - 0.000000000000000000000000005157 115.0
HFD1_k127_1711949_7 AAA domain - - - 0.0000000000000003621 87.0
HFD1_k127_1737570_0 Peptidase family M1 domain K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000002411 250.0
HFD1_k127_1737570_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000006388 160.0
HFD1_k127_175710_0 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 4.034e-209 669.0
HFD1_k127_175710_1 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000003853 241.0
HFD1_k127_175710_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000008279 122.0
HFD1_k127_175710_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000007907 61.0
HFD1_k127_1778993_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 538.0
HFD1_k127_1778993_1 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 354.0
HFD1_k127_1778993_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 303.0
HFD1_k127_1778993_3 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000005042 188.0
HFD1_k127_1778993_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000004503 171.0
HFD1_k127_1778993_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000094 146.0
HFD1_k127_1778993_6 polysaccharide deacetylase - - - 0.000000000000000000000009942 115.0
HFD1_k127_1778993_7 Rhs Family K20276 - - 0.000000001355 67.0
HFD1_k127_1778993_8 -O-antigen - - - 0.00000000145 71.0
HFD1_k127_1785167_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 519.0
HFD1_k127_1785167_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 494.0
HFD1_k127_1785167_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000009277 267.0
HFD1_k127_1785167_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002395 259.0
HFD1_k127_1785167_4 ZIP Zinc transporter K07238,K11021,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000004797 236.0
HFD1_k127_1785167_5 PFAM sigma-54 factor interaction domain-containing protein K10943 - - 0.00000000000000000000000000000000000000000000000000000000000003403 241.0
HFD1_k127_1785167_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000001083 193.0
HFD1_k127_180213_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006158 279.0
HFD1_k127_180213_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000001189 256.0
HFD1_k127_180213_2 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000009358 149.0
HFD1_k127_180213_3 - - - - 0.00000000000000000000000000009984 123.0
HFD1_k127_180213_4 Phosphatase K07093 - - 0.00000000000000002941 96.0
HFD1_k127_180213_5 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01848 - 5.4.99.2 0.00000288 49.0
HFD1_k127_1824988_0 Protein of unknown function (DUF2723) K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 396.0
HFD1_k127_1824988_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 335.0
HFD1_k127_1824988_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 324.0
HFD1_k127_1824988_3 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 308.0
HFD1_k127_1824988_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000002571 142.0
HFD1_k127_1824988_5 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000001311 140.0
HFD1_k127_1824988_6 methyltransferase - - - 0.0000000000000000000007972 98.0
HFD1_k127_1842285_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000006471 201.0
HFD1_k127_1842285_1 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000001842 174.0
HFD1_k127_1842285_2 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000000000000000000000000000000000003603 183.0
HFD1_k127_1842285_3 PFAM Methicillin resistance protein - - - 0.000000000005774 78.0
HFD1_k127_1853973_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 621.0
HFD1_k127_1853973_1 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 503.0
HFD1_k127_1853973_2 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 462.0
HFD1_k127_1853973_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 449.0
HFD1_k127_1853973_4 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 365.0
HFD1_k127_1853973_5 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 321.0
HFD1_k127_1853973_6 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000004352 234.0
HFD1_k127_1853973_7 PFAM PHP domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000002057 228.0
HFD1_k127_1853973_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000169 136.0
HFD1_k127_1853973_9 Helix-hairpin-helix motif K02237 - - 0.0000000000000002596 85.0
HFD1_k127_1879130_0 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 417.0
HFD1_k127_1879130_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 297.0
HFD1_k127_1879130_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000002 119.0
HFD1_k127_1879130_11 glyoxalase III activity - - - 0.000000000000000000000004094 117.0
HFD1_k127_1879130_12 Methionine biosynthesis protein MetW - - - 0.000000000000000000001763 100.0
HFD1_k127_1879130_13 Protein of unknown function (DUF664) - - - 0.000004375 56.0
HFD1_k127_1879130_14 sterol carrier protein - - - 0.00002614 54.0
HFD1_k127_1879130_2 Cytokinin dehydrogenase 1, FAD and cytokinin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000493 289.0
HFD1_k127_1879130_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005894 282.0
HFD1_k127_1879130_4 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000004093 204.0
HFD1_k127_1879130_5 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000002504 190.0
HFD1_k127_1879130_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000009885 178.0
HFD1_k127_1879130_7 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000001513 163.0
HFD1_k127_1879130_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000002774 139.0
HFD1_k127_1879130_9 Cytochrome c - - - 0.0000000000000000000000000000000001033 152.0
HFD1_k127_19018_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1356.0
HFD1_k127_19018_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 444.0
HFD1_k127_19018_10 Patatin phospholipase - - - 0.000000002182 70.0
HFD1_k127_19018_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003203 286.0
HFD1_k127_19018_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000002398 210.0
HFD1_k127_19018_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000001077 226.0
HFD1_k127_19018_5 ABC-2 family transporter protein K01992,K19341 - - 0.0000000000000000000000000000000000000000004167 175.0
HFD1_k127_19018_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000006182 162.0
HFD1_k127_19018_7 NnrS protein K07234 - - 0.000000000000000000000000000000001236 147.0
HFD1_k127_19018_8 Redoxin domain protein - - - 0.0000000000000000000005627 113.0
HFD1_k127_19018_9 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000009879 94.0
HFD1_k127_1902106_0 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 429.0
HFD1_k127_1902106_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001835 196.0
HFD1_k127_1902106_2 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000000216 83.0
HFD1_k127_1902106_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000001943 89.0
HFD1_k127_1906131_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003889 274.0
HFD1_k127_1906131_1 PFAM HD domain - - - 0.0000000000000000000000000000000000000000000613 182.0
HFD1_k127_1906131_2 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.00000003033 66.0
HFD1_k127_1906131_3 Two component signalling adaptor domain K03408 - - 0.000002775 60.0
HFD1_k127_1906131_4 Methyl-accepting chemotaxis protein K03406 - - 0.00003601 56.0
HFD1_k127_1970943_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0 1043.0
HFD1_k127_1970943_1 AAA domain - - - 1.318e-273 851.0
HFD1_k127_1970943_2 3-hydroxyacyl-CoA dehydrogenase K00074 GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.1.1.157 0.00000000000000000000000001839 124.0
HFD1_k127_1971929_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 467.0
HFD1_k127_1971929_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 376.0
HFD1_k127_1971929_10 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000001989 127.0
HFD1_k127_1971929_11 exo-alpha-(2->6)-sialidase activity - - - 0.0000000009772 72.0
HFD1_k127_1971929_2 Helix-hairpin-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 309.0
HFD1_k127_1971929_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 294.0
HFD1_k127_1971929_4 Proline dehydrogenase K00318 GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000331 264.0
HFD1_k127_1971929_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000382 201.0
HFD1_k127_1971929_6 SdpI/YhfL protein family - - - 0.000000000000000000000000000000000000000000000000000471 199.0
HFD1_k127_1971929_7 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000001163 181.0
HFD1_k127_1971929_8 DinB superfamily - - - 0.00000000000000000000000000000009363 133.0
HFD1_k127_1971929_9 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000001842 121.0
HFD1_k127_2001027_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.194e-201 646.0
HFD1_k127_2001027_1 Fic/DOC family N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 516.0
HFD1_k127_2001027_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 486.0
HFD1_k127_2001027_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 404.0
HFD1_k127_2001027_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 364.0
HFD1_k127_2001027_5 ABC transporter K02056 - 3.6.3.17 0.000000000002313 67.0
HFD1_k127_2028263_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 6.507e-255 798.0
HFD1_k127_2028263_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 474.0
HFD1_k127_2034942_0 polysaccharide export K01991 - - 0.0000000000000000000000000000000000004906 158.0
HFD1_k127_2034942_1 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000005405 156.0
HFD1_k127_2034942_2 acyl carrier protein - - - 0.0000000000001684 73.0
HFD1_k127_2034942_3 B12 binding domain - - - 0.0000000001047 69.0
HFD1_k127_2034942_4 Belongs to the P-Pant transferase superfamily K06133 - - 0.0001331 52.0
HFD1_k127_2089019_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001791 268.0
HFD1_k127_2089019_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000001236 194.0
HFD1_k127_214456_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.052e-296 943.0
HFD1_k127_214456_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 318.0
HFD1_k127_214456_2 Belongs to the UPF0235 family K09131 - - 0.0008264 43.0
HFD1_k127_2152113_0 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 379.0
HFD1_k127_2152113_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 360.0
HFD1_k127_2152113_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 295.0
HFD1_k127_2152113_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000002627 226.0
HFD1_k127_2152113_4 TonB-dependent receptor K16092 - - 0.00000000000000000000000000000000000000000000000558 195.0
HFD1_k127_2152113_5 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000001029 152.0
HFD1_k127_2152113_6 TPM domain K06872 - - 0.0000000000000000000000000000000000025 149.0
HFD1_k127_2152113_7 DinB family - - - 0.000000000000000000000000000000002768 143.0
HFD1_k127_2152113_8 nucleotidyltransferase activity - - - 0.00001205 55.0
HFD1_k127_2158411_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 450.0
HFD1_k127_2158411_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 376.0
HFD1_k127_2158411_10 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000001088 143.0
HFD1_k127_2158411_11 SpoVG K06412 - - 0.000000000000000000000000002829 113.0
HFD1_k127_2158411_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000006439 103.0
HFD1_k127_2158411_13 Binds together with S18 to 16S ribosomal RNA K01754,K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 0.00000000000000001283 87.0
HFD1_k127_2158411_14 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.0000000000000005747 93.0
HFD1_k127_2158411_15 LppC putative lipoprotein K07121 - - 0.0000001742 63.0
HFD1_k127_2158411_16 Ami_3 K01448 - 3.5.1.28 0.00008053 56.0
HFD1_k127_2158411_2 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005198 250.0
HFD1_k127_2158411_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000007257 233.0
HFD1_k127_2158411_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003379 195.0
HFD1_k127_2158411_5 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000002677 191.0
HFD1_k127_2158411_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000003695 185.0
HFD1_k127_2158411_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000002259 160.0
HFD1_k127_2158411_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000003188 170.0
HFD1_k127_2158411_9 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000172 131.0
HFD1_k127_2187073_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1329.0
HFD1_k127_2187073_1 Beta-eliminating lyase K01667 - 4.1.99.1 3.274e-194 616.0
HFD1_k127_2187073_10 - - - - 0.000000000000000000000000000000000000002597 154.0
HFD1_k127_2187073_12 Dimerisation domain - - - 0.00000000000000000000000000004937 134.0
HFD1_k127_2187073_13 DinB superfamily - - - 0.000000000000000000000000005069 120.0
HFD1_k127_2187073_14 Yqey-like protein K09117 - - 0.00000000000000000000000008212 113.0
HFD1_k127_2187073_15 Outer membrane efflux protein - - - 0.0000000000000000000000003469 120.0
HFD1_k127_2187073_16 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000003131 105.0
HFD1_k127_2187073_17 - - - - 0.0000000000000000003745 98.0
HFD1_k127_2187073_18 Zinc metalloprotease (Elastase) K20274 - - 0.000001168 60.0
HFD1_k127_2187073_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 443.0
HFD1_k127_2187073_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006228 295.0
HFD1_k127_2187073_4 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000004855 230.0
HFD1_k127_2187073_5 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001544 239.0
HFD1_k127_2187073_6 PFAM Class III cytochrome C family - - - 0.0000000000000000000000000000000000000000000000000007375 193.0
HFD1_k127_2187073_7 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000004703 198.0
HFD1_k127_2187073_8 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.000000000000000000000000000000000000000000000004394 193.0
HFD1_k127_2187073_9 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000001759 179.0
HFD1_k127_22338_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 607.0
HFD1_k127_22338_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008921 573.0
HFD1_k127_22338_10 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000005947 211.0
HFD1_k127_22338_11 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000002086 187.0
HFD1_k127_22338_12 SCO1/SenC K07152 - - 0.000000000000000000000000000002451 128.0
HFD1_k127_22338_13 type II secretion system protein E K02243,K02652 - - 0.0000000000000000000000003039 123.0
HFD1_k127_22338_14 Large-conductance mechanosensitive channel, MscL K03282 - - 0.000000000000000000000005772 108.0
HFD1_k127_22338_2 PFAM Type II secretion system protein E K02669,K12203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 330.0
HFD1_k127_22338_3 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 332.0
HFD1_k127_22338_4 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 309.0
HFD1_k127_22338_5 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 281.0
HFD1_k127_22338_6 ABC 3 transport family K02075,K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007274 274.0
HFD1_k127_22338_7 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001717 266.0
HFD1_k127_22338_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001025 245.0
HFD1_k127_22338_9 unfolded protein binding - - - 0.000000000000000000000000000000000000000000000000000000001186 215.0
HFD1_k127_2365838_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 358.0
HFD1_k127_2365838_1 PFAM peptidase M6, immune inhibitor A K09607 - - 0.0000048 58.0
HFD1_k127_24052_0 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001445 243.0
HFD1_k127_24052_1 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001843 223.0
HFD1_k127_24052_2 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000002972 140.0
HFD1_k127_24052_3 ompA family - - - 0.000003603 59.0
HFD1_k127_24052_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00003979 53.0
HFD1_k127_2410201_0 Berberine and berberine like - - - 6.735e-223 700.0
HFD1_k127_2410201_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.098e-217 703.0
HFD1_k127_2410201_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000007982 175.0
HFD1_k127_2410201_11 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000005925 159.0
HFD1_k127_2410201_12 Guanylyl transferase CofC like K09931 - - 0.00000000000000000000000000000009186 138.0
HFD1_k127_2410201_13 FR47-like protein - - - 0.00000000000000000000000003608 126.0
HFD1_k127_2410201_14 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000008212 109.0
HFD1_k127_2410201_15 - - - - 0.0000000000000002156 85.0
HFD1_k127_2410201_16 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000004537 75.0
HFD1_k127_2410201_17 Tetratricopeptide repeat - - - 0.0000000004804 70.0
HFD1_k127_2410201_2 DNA helicase K03654 - 3.6.4.12 5.672e-194 625.0
HFD1_k127_2410201_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 538.0
HFD1_k127_2410201_4 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 511.0
HFD1_k127_2410201_5 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 462.0
HFD1_k127_2410201_6 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 384.0
HFD1_k127_2410201_7 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 362.0
HFD1_k127_2410201_8 Glycoside hydrolase family 3 K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000001723 285.0
HFD1_k127_2410201_9 membrane - - - 0.00000000000000000000000000000000000000000000000000001045 192.0
HFD1_k127_2417834_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 2.588e-261 827.0
HFD1_k127_2417834_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 438.0
HFD1_k127_2417834_2 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 356.0
HFD1_k127_2417834_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000332 259.0
HFD1_k127_2417834_4 Peptidase family M16 - - - 0.000000000000000000000000000000002281 145.0
HFD1_k127_2417834_5 PFAM Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.00000000000001383 83.0
HFD1_k127_2417834_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002052 54.0
HFD1_k127_2423148_0 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 527.0
HFD1_k127_2423148_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000005984 208.0
HFD1_k127_2423148_2 Rhs Family K20276 - - 0.0000000000000000000441 106.0
HFD1_k127_2434247_0 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 417.0
HFD1_k127_2434247_1 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003158 294.0
HFD1_k127_2434247_2 metallopeptidase activity K06402 - - 0.00000000000000000000000000000000000000000000000000002277 195.0
HFD1_k127_2434247_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000001985 173.0
HFD1_k127_2434247_4 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000001391 93.0
HFD1_k127_2452939_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 586.0
HFD1_k127_2452939_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 536.0
HFD1_k127_2452939_10 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 286.0
HFD1_k127_2452939_11 Peptidase, S8 S53 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001418 296.0
HFD1_k127_2452939_13 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000001865 244.0
HFD1_k127_2452939_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002478 233.0
HFD1_k127_2452939_15 Adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000219 244.0
HFD1_k127_2452939_16 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000004745 234.0
HFD1_k127_2452939_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000001494 203.0
HFD1_k127_2452939_18 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000001278 200.0
HFD1_k127_2452939_19 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000003195 188.0
HFD1_k127_2452939_2 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 453.0
HFD1_k127_2452939_20 - - - - 0.000000000000000000000000000000000000000000000002795 179.0
HFD1_k127_2452939_21 - - - - 0.00000000000000000000000000000000000000000000004104 193.0
HFD1_k127_2452939_22 Glucose inhibited division protein A - - - 0.0000000000000000000000000000000000000000000001529 188.0
HFD1_k127_2452939_23 Putative adhesin - - - 0.0000000000000000000000000000000000000000000004139 193.0
HFD1_k127_2452939_24 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000006426 165.0
HFD1_k127_2452939_25 TPR repeat-containing protein - - - 0.0000000000000000000000000000000001585 152.0
HFD1_k127_2452939_26 protein maturation K13628 - - 0.000000000000000000000000000000001491 135.0
HFD1_k127_2452939_27 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000001245 136.0
HFD1_k127_2452939_28 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000003966 128.0
HFD1_k127_2452939_29 - - - - 0.00000000000000000000000000000351 135.0
HFD1_k127_2452939_3 Dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 434.0
HFD1_k127_2452939_30 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.00000000000000000001284 95.0
HFD1_k127_2452939_31 extracellular matrix structural constituent - - - 0.0000000000000003868 94.0
HFD1_k127_2452939_33 Outer membrane protein beta-barrel domain - - - 0.00003033 53.0
HFD1_k127_2452939_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 408.0
HFD1_k127_2452939_5 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 417.0
HFD1_k127_2452939_6 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 372.0
HFD1_k127_2452939_7 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 351.0
HFD1_k127_2452939_8 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 321.0
HFD1_k127_2452939_9 Pyridine nucleotide-disulphide oxidoreductase K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 337.0
HFD1_k127_2453438_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1167.0
HFD1_k127_2453438_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 421.0
HFD1_k127_2453438_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 360.0
HFD1_k127_2453438_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 337.0
HFD1_k127_2453438_4 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002679 249.0
HFD1_k127_2453438_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000000005429 162.0
HFD1_k127_2519600_0 Succinyl-CoA ligase like flavodoxin domain - - - 4.279e-215 696.0
HFD1_k127_2519600_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 382.0
HFD1_k127_2519600_2 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 329.0
HFD1_k127_2519600_3 Phosphoesterase, PA-phosphatase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001164 238.0
HFD1_k127_2519600_4 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000001103 175.0
HFD1_k127_2519600_5 of nitrite reductase and ring-hydroxylating K05710 - - 0.000000000000000000000000000009617 127.0
HFD1_k127_2519600_6 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000164 107.0
HFD1_k127_2519600_7 Iron-sulfur cluster assembly protein - - - 0.000000004924 65.0
HFD1_k127_2527275_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 610.0
HFD1_k127_2527275_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 566.0
HFD1_k127_2527275_10 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000001266 158.0
HFD1_k127_2527275_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000007533 156.0
HFD1_k127_2527275_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000026 115.0
HFD1_k127_2527275_13 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000001203 111.0
HFD1_k127_2527275_14 acr, cog1399 K07040 - - 0.00000000000000000001565 103.0
HFD1_k127_2527275_15 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000004297 91.0
HFD1_k127_2527275_16 Domain of unknown function (DUF4837) - - - 0.0000003932 61.0
HFD1_k127_2527275_17 Tetratricopeptide repeat - - - 0.00002065 57.0
HFD1_k127_2527275_18 AntiSigma factor - - - 0.0003691 51.0
HFD1_k127_2527275_19 ABC transporter, permease protein K02004 - - 0.0006046 45.0
HFD1_k127_2527275_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 407.0
HFD1_k127_2527275_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 376.0
HFD1_k127_2527275_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 371.0
HFD1_k127_2527275_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 325.0
HFD1_k127_2527275_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004966 284.0
HFD1_k127_2527275_7 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000007332 283.0
HFD1_k127_2527275_8 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000006421 262.0
HFD1_k127_2527275_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000002176 197.0
HFD1_k127_2610557_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1092.0
HFD1_k127_2610557_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 5.608e-225 713.0
HFD1_k127_2610557_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000001375 117.0
HFD1_k127_2610557_11 Ferredoxin - - - 0.0000000000000003943 91.0
HFD1_k127_2610557_12 Belongs to the UPF0434 family K09791 - - 0.00000000000115 79.0
HFD1_k127_2610557_13 Peptidase family C25 - - - 0.00000000005989 76.0
HFD1_k127_2610557_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 492.0
HFD1_k127_2610557_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 437.0
HFD1_k127_2610557_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 443.0
HFD1_k127_2610557_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 408.0
HFD1_k127_2610557_6 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 369.0
HFD1_k127_2610557_7 glucosamine-1-phosphate N-acetyltransferase activity K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000007253 236.0
HFD1_k127_2610557_8 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000006554 201.0
HFD1_k127_2610557_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000002659 177.0
HFD1_k127_2709822_0 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 461.0
HFD1_k127_2709822_1 Polysaccharide biosynthesis protein K01711,K15856 - 1.1.1.281,4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 439.0
HFD1_k127_2709822_10 polysaccharide biosynthetic process K03328 - - 0.0000000000009185 81.0
HFD1_k127_2709822_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 388.0
HFD1_k127_2709822_3 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 307.0
HFD1_k127_2709822_4 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000002235 252.0
HFD1_k127_2709822_5 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000001523 228.0
HFD1_k127_2709822_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000001194 194.0
HFD1_k127_2709822_7 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000002144 176.0
HFD1_k127_2709822_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000005612 135.0
HFD1_k127_2709822_9 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000001568 115.0
HFD1_k127_279380_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 531.0
HFD1_k127_279380_1 PFAM MgsA AAA ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 467.0
HFD1_k127_279380_2 Major facilitator superfamily - - - 0.0000000000003541 81.0
HFD1_k127_2862555_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 441.0
HFD1_k127_2862555_1 PFAM peptidase M61 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 424.0
HFD1_k127_2862555_2 DinB superfamily - - - 0.000000000000000000000000000000008874 136.0
HFD1_k127_288813_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 421.0
HFD1_k127_288813_1 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 415.0
HFD1_k127_288813_2 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000004366 221.0
HFD1_k127_288813_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000276 173.0
HFD1_k127_288813_4 Protein of unknown function (DUF3303) - - - 0.00000000000000000000000000000002978 132.0
HFD1_k127_288813_5 - - - - 0.00000000000001754 84.0
HFD1_k127_2903253_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 434.0
HFD1_k127_2903253_1 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 447.0
HFD1_k127_2903253_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 417.0
HFD1_k127_2903253_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000006136 209.0
HFD1_k127_2903253_4 Peptidase M56 - - - 0.00000000000000000000383 107.0
HFD1_k127_2903253_5 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000003275 76.0
HFD1_k127_2917244_0 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 2.66e-196 625.0
HFD1_k127_2917244_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 354.0
HFD1_k127_2917244_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 336.0
HFD1_k127_2917244_3 High-affinity nickel-transport protein K07241 - - 0.00000000000000000000000000000000000000000000000001837 199.0
HFD1_k127_2917244_4 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000003553 179.0
HFD1_k127_2917244_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000001899 161.0
HFD1_k127_2917244_6 Protein of unknown function (DUF1203) - - - 0.000000000000000000000000000000000000003318 151.0
HFD1_k127_2917244_7 Phage-related minor tail protein K01186,K21471,K22051 - 3.2.1.18 0.0000000000000000000003998 108.0
HFD1_k127_2922452_0 Uncharacterized protein family (UPF0051) K09014 - - 3.21e-230 721.0
HFD1_k127_2922452_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 600.0
HFD1_k127_2922452_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000007164 87.0
HFD1_k127_2922452_11 Cupredoxin-like domain - - - 0.0000000006067 67.0
HFD1_k127_2922452_12 Predicted integral membrane protein (DUF2269) - - - 0.0000002025 60.0
HFD1_k127_2922452_2 PFAM ABC transporter related K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 351.0
HFD1_k127_2922452_3 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 346.0
HFD1_k127_2922452_4 Acyl-protein synthetase, LuxE - - - 0.0000000000000000000000000000000000000000000000000000000000007825 227.0
HFD1_k127_2922452_5 Dienelactone hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000005308 214.0
HFD1_k127_2922452_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000009161 195.0
HFD1_k127_2922452_7 Acyl-CoA reductase (LuxC) - - - 0.0000000000000000000000000000000000000000000000000002109 207.0
HFD1_k127_2922452_8 MerR, DNA binding K19591 - - 0.0000000000000000000000000000000000008033 145.0
HFD1_k127_2922452_9 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000001885 109.0
HFD1_k127_2940694_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 455.0
HFD1_k127_2940694_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 355.0
HFD1_k127_2940694_10 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000001555 137.0
HFD1_k127_2940694_11 chain release factor K15034 - - 0.000000000000000000000000102 116.0
HFD1_k127_2940694_12 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.0000000000000001468 83.0
HFD1_k127_2940694_2 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 356.0
HFD1_k127_2940694_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 329.0
HFD1_k127_2940694_4 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 302.0
HFD1_k127_2940694_5 ABC transporter K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001979 270.0
HFD1_k127_2940694_6 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004474 284.0
HFD1_k127_2940694_7 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000000000000000000000000000001836 201.0
HFD1_k127_2940694_8 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000005074 148.0
HFD1_k127_2940694_9 PFAM ABC-2 type transporter K09696 - - 0.00000000000000000000000000000000000002943 158.0
HFD1_k127_2969539_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000008477 187.0
HFD1_k127_2969539_1 biopolymer transport protein K03559 - - 0.000000000001693 72.0
HFD1_k127_2969539_2 Belongs to the ABC transporter superfamily K02031,K02032,K13892,K13896 - - 0.00000001003 67.0
HFD1_k127_2969539_3 Yip1 domain - - - 0.00000005827 63.0
HFD1_k127_2969539_4 Biopolymer transport protein ExbD/TolR - - - 0.00009968 53.0
HFD1_k127_3081668_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 427.0
HFD1_k127_3081668_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 313.0
HFD1_k127_3081668_2 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000001834 222.0
HFD1_k127_3081668_3 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000001099 169.0
HFD1_k127_3081668_4 peptidyl-tyrosine sulfation K13992 - - 0.000000000000000000000000000000000000000001588 168.0
HFD1_k127_3081668_5 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000857 148.0
HFD1_k127_3081668_6 AntiSigma factor - - - 0.0000000000000000000000001214 122.0
HFD1_k127_3081668_7 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000003078 74.0
HFD1_k127_309281_0 Protein of unknown function (DUF3604) - - - 1.84e-312 980.0
HFD1_k127_309281_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 451.0
HFD1_k127_309281_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 405.0
HFD1_k127_309281_3 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 325.0
HFD1_k127_309281_4 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000763 228.0
HFD1_k127_309281_5 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000001759 164.0
HFD1_k127_309281_6 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000006007 149.0
HFD1_k127_3194859_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 464.0
HFD1_k127_3194859_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 416.0
HFD1_k127_3194859_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 331.0
HFD1_k127_3194859_3 Ribosomal protein S21 K02970 - - 0.000000000000001336 81.0
HFD1_k127_3194859_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000001565 72.0
HFD1_k127_3265629_0 Ribosomal protein S1 K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 2.864e-221 702.0
HFD1_k127_3265629_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 355.0
HFD1_k127_3265629_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 332.0
HFD1_k127_3265629_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000002072 267.0
HFD1_k127_3265629_4 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000002451 175.0
HFD1_k127_3265629_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000001324 166.0
HFD1_k127_3265629_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000002969 175.0
HFD1_k127_3265629_7 TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000003285 142.0
HFD1_k127_3274885_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 347.0
HFD1_k127_3274885_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 345.0
HFD1_k127_3274885_2 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 336.0
HFD1_k127_3274885_3 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000005534 260.0
HFD1_k127_3274885_4 Phosphoribosyl-ATP pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000003449 225.0
HFD1_k127_3274885_5 Putative zinc-finger K03088 - - 0.000000000000000000000000000000000000000000000003359 183.0
HFD1_k127_3274885_6 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000001201 162.0
HFD1_k127_3274885_7 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000001434 113.0
HFD1_k127_3274885_8 Domain of unknown function (DUF1844) - - - 0.00000000000000003266 95.0
HFD1_k127_3278222_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 6.635e-199 649.0
HFD1_k127_3278222_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002347 277.0
HFD1_k127_3278222_2 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000002355 256.0
HFD1_k127_3278222_3 diguanylate cyclase - - - 0.0000000000001577 85.0
HFD1_k127_3278222_4 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.000000000004357 80.0
HFD1_k127_3286591_0 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 311.0
HFD1_k127_3286591_1 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002979 276.0
HFD1_k127_3286591_2 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004539 293.0
HFD1_k127_3286591_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000001845 204.0
HFD1_k127_3286591_4 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000002484 184.0
HFD1_k127_3286591_5 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000006054 155.0
HFD1_k127_33098_0 RelA SpoT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 316.0
HFD1_k127_33098_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000005442 265.0
HFD1_k127_33098_2 sirohydrochlorin cobaltochelatase activity K03794,K03795 - 4.99.1.3,4.99.1.4 0.000000000000000000000000000000009319 131.0
HFD1_k127_33098_3 ADP-ribosyl-(Dinitrogen reductase) hydrolase K05521 - 3.2.2.24 0.00000000000000000000007297 109.0
HFD1_k127_3318271_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 550.0
HFD1_k127_3343513_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 493.0
HFD1_k127_3343513_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000001998 222.0
HFD1_k127_3343513_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000007586 205.0
HFD1_k127_3343513_3 Divergent polysaccharide deacetylase K09798 - - 0.00000000000001921 86.0
HFD1_k127_3346002_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 1.158e-210 670.0
HFD1_k127_3346002_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 504.0
HFD1_k127_3346002_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 325.0
HFD1_k127_3348233_0 Bacterial regulatory protein, Fis family K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 376.0
HFD1_k127_3348233_1 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000003346 74.0
HFD1_k127_3354493_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1026.0
HFD1_k127_3354493_1 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 612.0
HFD1_k127_3354493_10 - K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001727 261.0
HFD1_k127_3354493_11 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000002403 241.0
HFD1_k127_3354493_12 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000009198 220.0
HFD1_k127_3354493_13 dioxygenase of extradiol dioxygenase family K06991 - - 0.00000000000000000000000000000000000000000000002112 176.0
HFD1_k127_3354493_14 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000007343 197.0
HFD1_k127_3354493_15 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.000000000000000000000000000000000000000003762 163.0
HFD1_k127_3354493_16 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000002242 173.0
HFD1_k127_3354493_17 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000001254 169.0
HFD1_k127_3354493_18 ECF sigma factor - - - 0.00000000000000000000000000009969 124.0
HFD1_k127_3354493_19 Cold shock protein domain K03704 - - 0.0000000000000000000000000005488 113.0
HFD1_k127_3354493_2 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 548.0
HFD1_k127_3354493_20 Peptide-N-glycosidase F, N terminal - - - 0.0000000000000000000000000008685 128.0
HFD1_k127_3354493_21 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000002736 115.0
HFD1_k127_3354493_22 - - - - 0.0000000000000000002384 93.0
HFD1_k127_3354493_23 - - - - 0.00000000002568 74.0
HFD1_k127_3354493_3 growth of symbiont in host cell K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 558.0
HFD1_k127_3354493_4 Beta-eliminating lyase K01668 - 4.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 525.0
HFD1_k127_3354493_5 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 412.0
HFD1_k127_3354493_6 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 379.0
HFD1_k127_3354493_7 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 392.0
HFD1_k127_3354493_8 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 342.0
HFD1_k127_3354493_9 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005433 282.0
HFD1_k127_3371448_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 464.0
HFD1_k127_3371448_1 Transketolase, pyrimidine binding domain K00162,K00167,K21417 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 420.0
HFD1_k127_3371448_2 Dehydrogenase E1 component K00161,K00166,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 394.0
HFD1_k127_3371448_3 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000002201 166.0
HFD1_k127_3371448_4 e3 binding domain K00658,K09699 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.168,2.3.1.61 0.00000000000000000000000000000000000000001513 163.0
HFD1_k127_3406683_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.229e-310 978.0
HFD1_k127_3406683_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000002833 220.0
HFD1_k127_3406683_2 PFAM alpha beta hydrolase fold K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000006257 222.0
HFD1_k127_3406683_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000215 212.0
HFD1_k127_3406683_4 PFAM glycosyl transferase family 2 K20444 - - 0.00000000000000000000001898 111.0
HFD1_k127_3406683_5 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000001969 114.0
HFD1_k127_3462364_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 374.0
HFD1_k127_3462364_1 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000000008203 195.0
HFD1_k127_3462364_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000002671 77.0
HFD1_k127_3483480_0 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 361.0
HFD1_k127_3483480_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 323.0
HFD1_k127_3483480_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 320.0
HFD1_k127_3483480_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007522 289.0
HFD1_k127_3483480_4 PFAM Outer membrane efflux protein - - - 0.0000000007506 65.0
HFD1_k127_3529649_0 iron ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001794 237.0
HFD1_k127_3529649_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000004782 220.0
HFD1_k127_3529649_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000101 182.0
HFD1_k127_3529649_3 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000003071 183.0
HFD1_k127_3529649_4 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000001407 170.0
HFD1_k127_3529649_5 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000559 152.0
HFD1_k127_3529649_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000001084 108.0
HFD1_k127_3529649_7 MlaD protein K02067 - - 0.0000000000000000001123 100.0
HFD1_k127_3529649_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000002157 64.0
HFD1_k127_3532575_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K02827,K15408 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0020037,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0040007,GO:0042773,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902494,GO:1902600 1.10.3.10,1.10.3.12,1.9.3.1 1.66e-215 681.0
HFD1_k127_3532575_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 477.0
HFD1_k127_3532575_10 protein required for cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000254 139.0
HFD1_k127_3532575_11 copper ion binding K02258 GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000006386 123.0
HFD1_k127_3532575_12 Peptidase family M48 - - - 0.000000000000000000002239 104.0
HFD1_k127_3532575_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000004757 61.0
HFD1_k127_3532575_14 Protein of unknown function (DUF3341) - - - 0.00007344 45.0
HFD1_k127_3532575_15 Peptidase family M3 K01392 - 3.4.24.15 0.0001812 44.0
HFD1_k127_3532575_16 Uncharacterized conserved protein (DUF2249) - - - 0.0007327 51.0
HFD1_k127_3532575_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 474.0
HFD1_k127_3532575_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 337.0
HFD1_k127_3532575_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 334.0
HFD1_k127_3532575_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 314.0
HFD1_k127_3532575_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002529 273.0
HFD1_k127_3532575_7 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000006557 224.0
HFD1_k127_3532575_8 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000003238 162.0
HFD1_k127_3532575_9 Cytochrome c K07243 - - 0.0000000000000000000000000000000000000000009298 179.0
HFD1_k127_3696755_0 PFAM Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 364.0
HFD1_k127_3696755_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 341.0
HFD1_k127_3696755_2 transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004065 296.0
HFD1_k127_3696755_3 Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.00000000000000000000000000000000000000000000000000001228 197.0
HFD1_k127_3696755_4 Transport and Golgi organisation 2 - - - 0.000000000000000005492 94.0
HFD1_k127_3696755_5 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00008039 50.0
HFD1_k127_370363_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 447.0
HFD1_k127_370363_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 294.0
HFD1_k127_370363_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005252 280.0
HFD1_k127_370363_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000003231 172.0
HFD1_k127_3723603_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1053.0
HFD1_k127_3723603_1 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 589.0
HFD1_k127_3723603_10 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000005059 199.0
HFD1_k127_3723603_11 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000002511 162.0
HFD1_k127_3723603_12 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000000000007979 160.0
HFD1_k127_3723603_13 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000287 132.0
HFD1_k127_3723603_14 Outer membrane lipoprotein - - - 0.00000000000000000000002748 113.0
HFD1_k127_3723603_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.000000000000000000003507 100.0
HFD1_k127_3723603_16 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000003636 100.0
HFD1_k127_3723603_17 TonB C terminal K03646,K03832 - - 0.0000000000000005458 92.0
HFD1_k127_3723603_18 LysM domain - - - 0.0000000006707 70.0
HFD1_k127_3723603_19 PFAM VanZ like - - - 0.00000003729 66.0
HFD1_k127_3723603_2 Cys/Met metabolism PLP-dependent enzyme K01760,K01761 - 4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 556.0
HFD1_k127_3723603_20 Involved in the tonB-independent uptake of proteins K03641 - - 0.000005231 59.0
HFD1_k127_3723603_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 464.0
HFD1_k127_3723603_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 438.0
HFD1_k127_3723603_5 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 378.0
HFD1_k127_3723603_6 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 341.0
HFD1_k127_3723603_7 SMART Metal-dependent phosphohydrolase, HD region K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 342.0
HFD1_k127_3723603_8 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 314.0
HFD1_k127_3723603_9 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 291.0
HFD1_k127_3729498_0 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 595.0
HFD1_k127_3729498_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 445.0
HFD1_k127_3729498_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000006979 218.0
HFD1_k127_3729498_11 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000104 205.0
HFD1_k127_3729498_12 ATP:ADP antiporter activity K01932,K03301 - - 0.000000000000000000000000000000000000000000000000002743 196.0
HFD1_k127_3729498_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000007591 168.0
HFD1_k127_3729498_14 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000001373 150.0
HFD1_k127_3729498_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000615 142.0
HFD1_k127_3729498_16 dehydrogenase e1 component K00164 - 1.2.4.2 0.00000000000000001495 91.0
HFD1_k127_3729498_17 Purple acid Phosphatase, N-terminal domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000007959 93.0
HFD1_k127_3729498_18 Surface antigen - - - 0.0000008329 61.0
HFD1_k127_3729498_19 - - - - 0.000004945 53.0
HFD1_k127_3729498_2 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 394.0
HFD1_k127_3729498_3 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 347.0
HFD1_k127_3729498_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 318.0
HFD1_k127_3729498_5 Polycystin cation channel K08714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 290.0
HFD1_k127_3729498_6 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 284.0
HFD1_k127_3729498_7 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008552 273.0
HFD1_k127_3729498_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001069 262.0
HFD1_k127_3729498_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000005803 216.0
HFD1_k127_374534_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 587.0
HFD1_k127_374534_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000851 233.0
HFD1_k127_374534_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000001517 158.0
HFD1_k127_374534_3 Cold-shock protein K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000001885 109.0
HFD1_k127_3746905_0 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 406.0
HFD1_k127_3746905_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 313.0
HFD1_k127_3746905_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000456 246.0
HFD1_k127_3746905_3 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000007003 168.0
HFD1_k127_3746905_4 PFAM glycosyl transferase family 9 K02843 - - 0.0000000000000000000000003154 117.0
HFD1_k127_3746905_5 HEAT repeat - - - 0.000000000001971 81.0
HFD1_k127_3746905_6 Putative zinc-finger - - - 0.000001061 60.0
HFD1_k127_3746905_7 serine threonine protein kinase K12132 - 2.7.11.1 0.00002329 52.0
HFD1_k127_3758966_0 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 527.0
HFD1_k127_3758966_1 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000000000006719 240.0
HFD1_k127_3758966_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000001151 200.0
HFD1_k127_3758966_3 PFAM peptidase M20 - - - 0.00000000000000000000000000000009207 125.0
HFD1_k127_3758966_4 CARDB - - - 0.000000000000000001556 102.0
HFD1_k127_3758966_5 Evidence 5 No homology to any previously reported sequences - - - 0.0000000002864 74.0
HFD1_k127_3758966_6 Acetyltransferase (GNAT) domain - - - 0.0000003794 62.0
HFD1_k127_3768215_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 297.0
HFD1_k127_3768215_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000287 235.0
HFD1_k127_3768215_2 ECF sigma factor - - - 0.00000000000000002839 82.0
HFD1_k127_3912699_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 484.0
HFD1_k127_3912699_1 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 477.0
HFD1_k127_3912699_2 PFAM response regulator receiver K07657 - - 0.00000000000000000000000000000007888 128.0
HFD1_k127_3912699_3 NHL repeat - - - 0.0000000000000000000000009596 107.0
HFD1_k127_3912699_4 Belongs to the UPF0234 family K09767 - - 0.000000000000000000005233 98.0
HFD1_k127_3912699_5 Pilus assembly protein - - - 0.0000001754 64.0
HFD1_k127_3912699_6 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0001219 48.0
HFD1_k127_4028943_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 443.0
HFD1_k127_4028943_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 411.0
HFD1_k127_4028943_2 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 398.0
HFD1_k127_4028943_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000243 181.0
HFD1_k127_4028943_4 deoxyhypusine monooxygenase activity K05384 - - 0.0000000000000000001709 101.0
HFD1_k127_4028943_5 PFAM peptidase M6, immune inhibitor A - - - 0.00000000000000000423 93.0
HFD1_k127_4028943_6 SMART Tetratricopeptide repeat - - - 0.000008299 59.0
HFD1_k127_4028943_7 transferase activity, transferring glycosyl groups - - - 0.00002308 56.0
HFD1_k127_4028943_8 transmembrane transport - - - 0.00006391 50.0
HFD1_k127_4034996_0 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 355.0
HFD1_k127_4034996_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000003876 267.0
HFD1_k127_4034996_2 - - - - 0.0000000004836 67.0
HFD1_k127_4034996_3 Protein tyrosine kinase - - - 0.0001262 54.0
HFD1_k127_4036858_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 2.097e-240 749.0
HFD1_k127_4036858_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 541.0
HFD1_k127_4036858_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000008636 254.0
HFD1_k127_4036858_3 proton-transporting ATP synthase activity, rotational mechanism K02114 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000007031 101.0
HFD1_k127_4041488_0 NmrA-like family K19267 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 340.0
HFD1_k127_4041488_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000003067 239.0
HFD1_k127_4041488_2 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000002689 219.0
HFD1_k127_4041488_3 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000001548 218.0
HFD1_k127_4041488_4 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000004638 205.0
HFD1_k127_4041488_5 Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000004897 186.0
HFD1_k127_4041488_6 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000002809 145.0
HFD1_k127_4041488_7 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000005781 149.0
HFD1_k127_4041488_8 Tetratricopeptide repeat - - - 0.00000000000000000000000098 120.0
HFD1_k127_4081334_0 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 388.0
HFD1_k127_4081334_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 354.0
HFD1_k127_4081334_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.0000000000000000000000000000000000000004623 164.0
HFD1_k127_4089735_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 6.357e-261 814.0
HFD1_k127_4089735_1 eight transmembrane protein EpsH - - - 0.0000000000000000000003856 102.0
HFD1_k127_4090767_0 FAD linked oxidase domain protein - - - 4.727e-241 752.0
HFD1_k127_4090767_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.588e-221 710.0
HFD1_k127_4090767_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 381.0
HFD1_k127_4090767_3 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 366.0
HFD1_k127_4090767_4 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002151 293.0
HFD1_k127_4090767_5 cytochrome c nitrite reductase K15876 - - 0.00000000000000000000000000000000000000000000000002882 186.0
HFD1_k127_4090767_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000001441 158.0
HFD1_k127_4090767_7 - - - - 0.0000000000000008557 78.0
HFD1_k127_4090767_8 PcfJ-like protein - - - 0.000000000000002678 89.0
HFD1_k127_4092746_0 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 379.0
HFD1_k127_4092746_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 342.0
HFD1_k127_4092746_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 304.0
HFD1_k127_4092746_3 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 300.0
HFD1_k127_4092746_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003401 289.0
HFD1_k127_4092746_5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000131 236.0
HFD1_k127_4092746_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000001803 183.0
HFD1_k127_4092746_7 Phospholipid methyltransferase - - - 0.000000000000000000000000000004855 136.0
HFD1_k127_4092746_8 Recombinase zinc beta ribbon domain - - - 0.000003052 51.0
HFD1_k127_4092746_9 Recombinase zinc beta ribbon domain K06400 - - 0.000005702 51.0
HFD1_k127_4119827_0 Belongs to the ClpA ClpB family K03696 - - 1.3e-322 1016.0
HFD1_k127_4119827_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 587.0
HFD1_k127_4119827_10 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 321.0
HFD1_k127_4119827_11 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007885 285.0
HFD1_k127_4119827_12 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000001195 278.0
HFD1_k127_4119827_13 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000002077 227.0
HFD1_k127_4119827_14 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000001675 228.0
HFD1_k127_4119827_15 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000001006 210.0
HFD1_k127_4119827_16 protein with conserved CXXC pairs K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.000000000000000000000000000000000000000000000005387 178.0
HFD1_k127_4119827_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000001666 197.0
HFD1_k127_4119827_18 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000002381 171.0
HFD1_k127_4119827_19 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000004847 162.0
HFD1_k127_4119827_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 560.0
HFD1_k127_4119827_20 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000003196 118.0
HFD1_k127_4119827_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 537.0
HFD1_k127_4119827_4 PFAM Type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 508.0
HFD1_k127_4119827_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 494.0
HFD1_k127_4119827_6 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 469.0
HFD1_k127_4119827_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 401.0
HFD1_k127_4119827_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 340.0
HFD1_k127_4119827_9 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 332.0
HFD1_k127_4178583_0 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006257 275.0
HFD1_k127_4178583_1 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000425 215.0
HFD1_k127_4178583_2 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000009966 213.0
HFD1_k127_4178583_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000006925 189.0
HFD1_k127_4178583_4 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000005346 177.0
HFD1_k127_4178583_5 Transcriptional regulator K07729 - - 0.0000000000000000000007802 104.0
HFD1_k127_4190606_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 430.0
HFD1_k127_4190606_1 COG0520 Selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 399.0
HFD1_k127_4190606_2 Aminotransferase class-V - - - 0.0000000000000000000000000004331 119.0
HFD1_k127_4190606_3 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000005375 107.0
HFD1_k127_4190606_4 SnoaL-like domain - - - 0.0000000000000000000000116 103.0
HFD1_k127_4223011_0 HI0933-like protein - - - 6.36e-240 763.0
HFD1_k127_4223011_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 469.0
HFD1_k127_4223011_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 402.0
HFD1_k127_4223011_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000006976 244.0
HFD1_k127_4223011_4 AraC-like ligand binding domain - - - 0.0000000000000000000000005132 115.0
HFD1_k127_4223011_5 SnoaL-like domain - - - 0.00005527 51.0
HFD1_k127_4239521_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.649e-228 731.0
HFD1_k127_4239521_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 503.0
HFD1_k127_4239521_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 304.0
HFD1_k127_4239521_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006355 295.0
HFD1_k127_4239521_4 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001593 276.0
HFD1_k127_4239521_5 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000001123 247.0
HFD1_k127_4239521_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000002411 212.0
HFD1_k127_4239521_7 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.000000000000000000000000000000000000000000000000003405 203.0
HFD1_k127_4239521_8 Divergent PAP2 family K09775 - - 0.000000000000000000000000000000002463 137.0
HFD1_k127_4239521_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000001415 64.0
HFD1_k127_4331182_0 dehydrogenase e1 component K00164 - 1.2.4.2 5.789e-316 986.0
HFD1_k127_4331182_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000001179 105.0
HFD1_k127_4350790_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001013 290.0
HFD1_k127_4350790_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002001 279.0
HFD1_k127_4350790_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000005726 243.0
HFD1_k127_4350790_3 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000004251 218.0
HFD1_k127_4350790_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000000001418 151.0
HFD1_k127_4350790_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000001928 123.0
HFD1_k127_4350790_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000006329 87.0
HFD1_k127_4350790_8 - - - - 0.00001262 49.0
HFD1_k127_4373971_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 601.0
HFD1_k127_4373971_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 398.0
HFD1_k127_4373971_10 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000002551 185.0
HFD1_k127_4373971_11 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000001824 177.0
HFD1_k127_4373971_12 Thioredoxin-like K02199 - - 0.0000000000000000000000000000000000001379 149.0
HFD1_k127_4373971_13 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000001226 138.0
HFD1_k127_4373971_14 glycogen phosphorylase activity K00688,K00691 - 2.4.1.1,2.4.1.8 0.000000000000000000000000000000002791 132.0
HFD1_k127_4373971_15 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000009319 131.0
HFD1_k127_4373971_16 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.00000000000000000000000000002412 128.0
HFD1_k127_4373971_17 - - - - 0.0000000000000000000000001002 108.0
HFD1_k127_4373971_18 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000001141 109.0
HFD1_k127_4373971_19 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.00000000000000000006941 95.0
HFD1_k127_4373971_2 serine-type peptidase activity K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 405.0
HFD1_k127_4373971_20 4-epimerase K01628 - 4.1.2.17 0.0000000000000000001969 99.0
HFD1_k127_4373971_21 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000002101 96.0
HFD1_k127_4373971_22 - - - - 0.000000000000002215 89.0
HFD1_k127_4373971_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 370.0
HFD1_k127_4373971_4 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 307.0
HFD1_k127_4373971_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 297.0
HFD1_k127_4373971_6 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004009 244.0
HFD1_k127_4373971_7 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000003519 240.0
HFD1_k127_4373971_8 Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000001052 219.0
HFD1_k127_4373971_9 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000003156 215.0
HFD1_k127_4379992_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 351.0
HFD1_k127_4379992_1 PFAM Amidohydrolase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 336.0
HFD1_k127_4388257_0 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000443 267.0
HFD1_k127_4388257_1 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000007773 215.0
HFD1_k127_4388257_2 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000000105 173.0
HFD1_k127_4388257_3 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.000000000000000000000000001836 120.0
HFD1_k127_4439199_0 o-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 291.0
HFD1_k127_4439199_1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0000000000000000000000000000000000000000000006197 171.0
HFD1_k127_4439199_2 Acetyltransferase, gnat family K22477 - 2.3.1.1 0.00000000000000000000000002466 120.0
HFD1_k127_4439199_3 acetyltransferase - - - 0.0009687 42.0
HFD1_k127_4450377_0 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005998 235.0
HFD1_k127_4450377_1 - - - - 0.00000000000007322 73.0
HFD1_k127_4450377_2 curli production assembly transport component CsgG - - - 0.0000003649 63.0
HFD1_k127_4496800_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 415.0
HFD1_k127_4496800_1 Chain length determinant protein - - - 0.000000000004733 80.0
HFD1_k127_4496800_2 PFAM lipopolysaccharide biosynthesis protein - - - 0.000000001745 70.0
HFD1_k127_4496800_3 polysaccharide export K01991,K20988 - - 0.00000001698 66.0
HFD1_k127_450208_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 1.015e-200 648.0
HFD1_k127_450208_1 exonuclease K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 469.0
HFD1_k127_450208_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 389.0
HFD1_k127_450208_3 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000009335 194.0
HFD1_k127_450208_4 PFAM Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000009861 182.0
HFD1_k127_450208_5 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000002592 126.0
HFD1_k127_4505745_0 ABC transporter - - - 2.4e-201 641.0
HFD1_k127_4505745_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 446.0
HFD1_k127_4505745_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 412.0
HFD1_k127_4505745_3 Protein of unknown function (DUF3798) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 366.0
HFD1_k127_4505745_4 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000003269 129.0
HFD1_k127_4505745_5 Protein of unknown function, DUF255 - - - 0.00000000000000000000005872 107.0
HFD1_k127_4505745_6 major facilitator superfamily K08161 GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000001431 86.0
HFD1_k127_4505745_8 Haloacid dehalogenase-like hydrolase - - - 0.000000001176 61.0
HFD1_k127_4523386_0 CHAD domain containing protein - - - 0.000000000000000000000000000000000000000001361 175.0
HFD1_k127_4523386_1 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000008021 113.0
HFD1_k127_4523386_3 Sigma-70, region 4 K03088 - - 0.00000000000000000004792 98.0
HFD1_k127_4523386_4 Fe2 -dicitrate sensor, membrane component K07165 - - 0.0007822 51.0
HFD1_k127_454839_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003186 283.0
HFD1_k127_454839_1 - K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000002821 179.0
HFD1_k127_454839_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000005115 165.0
HFD1_k127_454839_3 - - - - 0.000000000000000000000000000000000000000007434 170.0
HFD1_k127_454839_4 FR47-like protein K03823 - 2.3.1.183 0.0000000000000000000000000003252 130.0
HFD1_k127_454839_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000007678 100.0
HFD1_k127_454839_6 - - - - 0.00000000000000004175 84.0
HFD1_k127_454839_7 - - - - 0.000000851 59.0
HFD1_k127_454839_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.00001512 48.0
HFD1_k127_461959_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000001421 208.0
HFD1_k127_461959_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000006093 134.0
HFD1_k127_461959_2 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000001197 120.0
HFD1_k127_461959_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0001624 55.0
HFD1_k127_4636495_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000712 291.0
HFD1_k127_4636495_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000002322 247.0
HFD1_k127_4636495_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000008465 98.0
HFD1_k127_4794510_0 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000003439 249.0
HFD1_k127_4794510_1 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000002969 186.0
HFD1_k127_4794510_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000009461 89.0
HFD1_k127_4891443_0 PFAM FAD linked oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 507.0
HFD1_k127_4891443_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 395.0
HFD1_k127_4891443_2 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 370.0
HFD1_k127_4891443_3 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000001002 188.0
HFD1_k127_4891443_4 Predicted membrane protein (DUF2231) - - - 0.0000000000001615 77.0
HFD1_k127_4931910_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 484.0
HFD1_k127_4931910_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 316.0
HFD1_k127_4931910_2 NmrA-like family - - - 0.000000000000000000000006304 105.0
HFD1_k127_4931910_3 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0001038 55.0
HFD1_k127_4963995_0 Dehydrogenase E1 component K11381 - 1.2.4.4 2.798e-274 862.0
HFD1_k127_4963995_1 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001898 216.0
HFD1_k127_4963995_2 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000004225 142.0
HFD1_k127_4963995_3 Metallo-beta-lactamase superfamily - - - 0.000000000000001006 81.0
HFD1_k127_4963995_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000008341 68.0
HFD1_k127_4974118_0 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 495.0
HFD1_k127_4974118_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 456.0
HFD1_k127_4974118_2 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 466.0
HFD1_k127_4974118_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 388.0
HFD1_k127_4974118_4 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000001245 248.0
HFD1_k127_4974118_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000002075 158.0
HFD1_k127_4974118_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000004414 121.0
HFD1_k127_4974118_7 protein trimerization K15368 - - 0.000000249 61.0
HFD1_k127_4974118_8 TM2 domain - - - 0.0000003332 62.0
HFD1_k127_4974118_9 Binds directly to 16S ribosomal RNA K02968 - - 0.0000004377 55.0
HFD1_k127_5015942_0 Peptidase S46 - - - 6.834e-252 798.0
HFD1_k127_5015942_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
HFD1_k127_5017277_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.644e-236 755.0
HFD1_k127_5017277_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 329.0
HFD1_k127_5017277_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000001371 190.0
HFD1_k127_5017277_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000003614 172.0
HFD1_k127_5070076_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 554.0
HFD1_k127_5070076_1 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 404.0
HFD1_k127_5070076_10 Lipoprotein K05811 - - 0.0001086 51.0
HFD1_k127_5070076_2 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 346.0
HFD1_k127_5070076_3 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000006751 276.0
HFD1_k127_5070076_4 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000002951 239.0
HFD1_k127_5070076_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000004918 180.0
HFD1_k127_5070076_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000007128 164.0
HFD1_k127_5070076_7 Histidine kinase K14986 - 2.7.13.3 0.0000000000000000000000000000000000002059 158.0
HFD1_k127_5070076_8 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000000006413 115.0
HFD1_k127_5070076_9 Ricin-type beta-trefoil lectin domain - - - 0.00009515 55.0
HFD1_k127_5140632_0 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 393.0
HFD1_k127_5140632_1 Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 317.0
HFD1_k127_5140632_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000001581 271.0
HFD1_k127_5140632_3 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002436 254.0
HFD1_k127_5140632_4 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000001446 244.0
HFD1_k127_5140632_5 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000002459 161.0
HFD1_k127_5140632_6 isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000001305 156.0
HFD1_k127_5182277_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 301.0
HFD1_k127_5182277_1 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000002009 197.0
HFD1_k127_5182277_2 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000001611 158.0
HFD1_k127_5182277_3 - - - - 0.00000000000000001963 93.0
HFD1_k127_5182277_4 - - - - 0.0000000000000001369 93.0
HFD1_k127_5182277_5 metal cluster binding K06940 - - 0.0000000001628 66.0
HFD1_k127_5182277_6 Protein of unknown function, DUF255 - - - 0.000009908 55.0
HFD1_k127_5193174_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 530.0
HFD1_k127_5193174_1 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000002028 237.0
HFD1_k127_5193174_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000002 81.0
HFD1_k127_5196302_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 570.0
HFD1_k127_5196302_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 301.0
HFD1_k127_5196302_2 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000281 234.0
HFD1_k127_5196302_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000003092 227.0
HFD1_k127_5196302_4 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000001998 214.0
HFD1_k127_5196302_5 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000827 209.0
HFD1_k127_5196302_6 4-amino-4-deoxy-L-arabinose transferase activity K07264 - 2.4.2.43 0.00000000000000000000000000000000000000000000000000002051 210.0
HFD1_k127_5196302_7 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000002908 144.0
HFD1_k127_5196302_8 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000009116 117.0
HFD1_k127_5196302_9 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000548 68.0
HFD1_k127_5212465_0 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 565.0
HFD1_k127_5212465_1 PFAM ABC-1 domain protein K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 441.0
HFD1_k127_5212465_2 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000008175 243.0
HFD1_k127_5212465_3 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000003574 214.0
HFD1_k127_5212465_5 regulation of translation K03704,K05809 - - 0.0000000000002702 82.0
HFD1_k127_5212465_6 Glycerol-3-phosphate K13507 - 2.3.1.15,2.3.1.42 0.000000008188 64.0
HFD1_k127_5239838_0 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 615.0
HFD1_k127_5239838_1 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 418.0
HFD1_k127_5239838_10 Domain of unknown function (DUF4332) - - - 0.00000000000003187 78.0
HFD1_k127_5239838_2 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 359.0
HFD1_k127_5239838_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 319.0
HFD1_k127_5239838_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 322.0
HFD1_k127_5239838_5 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000001055 239.0
HFD1_k127_5239838_6 neuronal K10380,K21440 GO:0000902,GO:0000904,GO:0001508,GO:0002027,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003205,GO:0003230,GO:0003279,GO:0003283,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005911,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006888,GO:0006928,GO:0006935,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0007009,GO:0007154,GO:0007165,GO:0007267,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007507,GO:0008015,GO:0008016,GO:0008092,GO:0008104,GO:0008150,GO:0009605,GO:0009653,GO:0009893,GO:0009987,GO:0010171,GO:0010256,GO:0010468,GO:0010522,GO:0010604,GO:0010628,GO:0010646,GO:0010880,GO:0010881,GO:0010882,GO:0010959,GO:0014069,GO:0014704,GO:0015459,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016247,GO:0016323,GO:0016328,GO:0019222,GO:0019722,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0022008,GO:0022898,GO:0023051,GO:0023052,GO:0030001,GO:0030003,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030048,GO:0030054,GO:0030154,GO:0030182,GO:0030315,GO:0030507,GO:0030674,GO:0031175,GO:0031224,GO:0031226,GO:0031430,GO:0031647,GO:0031672,GO:0031674,GO:0032279,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032879,GO:0032970,GO:0032989,GO:0032990,GO:0033036,GO:0033292,GO:0033365,GO:0033563,GO:0034394,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035556,GO:0035637,GO:0036309,GO:0036371,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042592,GO:0042692,GO:0043034,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043292,GO:0044057,GO:0044093,GO:0044291,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044464,GO:0045202,GO:0045927,GO:0046907,GO:0048193,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048522,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050821,GO:0050839,GO:0050896,GO:0051049,GO:0051050,GO:0051094,GO:0051117,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051279,GO:0051282,GO:0051641,GO:0051649,GO:0051716,GO:0051899,GO:0051924,GO:0051928,GO:0055001,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055117,GO:0060047,GO:0060048,GO:0060090,GO:0060255,GO:0060306,GO:0060307,GO:0060341,GO:0061024,GO:0061061,GO:0061337,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070252,GO:0070296,GO:0070727,GO:0070838,GO:0070972,GO:0071840,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0072657,GO:0072659,GO:0086001,GO:0086002,GO:0086003,GO:0086004,GO:0086005,GO:0086010,GO:0086012,GO:0086014,GO:0086015,GO:0086018,GO:0086019,GO:0086026,GO:0086036,GO:0086046,GO:0086065,GO:0086066,GO:0086070,GO:0086091,GO:0090257,GO:0097458,GO:0097485,GO:0098590,GO:0098771,GO:0098772,GO:0098794,GO:0098900,GO:0098901,GO:0098904,GO:0098907,GO:0098910,GO:0098984,GO:0099080,GO:0099081,GO:0099106,GO:0099512,GO:0099572,GO:0099623,GO:0120036,GO:0120039,GO:1901016,GO:1901018,GO:1901019,GO:1901021,GO:1901379,GO:1901381,GO:1903115,GO:1903169,GO:1903522,GO:1903779,GO:1904062,GO:1904064,GO:1904427,GO:1990778,GO:2001257,GO:2001259 - 0.0000000000000000000000000000000000000000000001212 186.0
HFD1_k127_5239838_7 response regulator - - - 0.000000000000000000001499 106.0
HFD1_k127_5239838_8 Psort location CytoplasmicMembrane, score K19225 - 3.4.21.105 0.00000000000001511 83.0
HFD1_k127_5239838_9 Domain of unknown function (DUF4332) - - - 0.00000000000001563 83.0
HFD1_k127_5301246_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 440.0
HFD1_k127_5301246_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 403.0
HFD1_k127_5301246_10 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000002889 184.0
HFD1_k127_5301246_11 Hit family K19710 - 2.7.7.53 0.00000000000000000000000000000000000000003232 168.0
HFD1_k127_5301246_12 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000004518 160.0
HFD1_k127_5301246_13 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000003274 90.0
HFD1_k127_5301246_14 Family membership K08884 - 2.7.11.1 0.00000000000003047 85.0
HFD1_k127_5301246_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000005621 65.0
HFD1_k127_5301246_16 glyoxalase III activity - - - 0.000000009872 66.0
HFD1_k127_5301246_17 PFAM Cell envelope-related transcriptional attenuator domain - - - 0.0000005956 57.0
HFD1_k127_5301246_18 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000002095 56.0
HFD1_k127_5301246_2 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 402.0
HFD1_k127_5301246_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 302.0
HFD1_k127_5301246_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000008035 268.0
HFD1_k127_5301246_5 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000005185 226.0
HFD1_k127_5301246_6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000005484 224.0
HFD1_k127_5301246_7 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.00000000000000000000000000000000000000000000000000001415 200.0
HFD1_k127_5301246_8 Peptidylprolyl isomerase K01802,K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000007083 193.0
HFD1_k127_5301246_9 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000001608 182.0
HFD1_k127_5322681_0 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 501.0
HFD1_k127_5322681_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 458.0
HFD1_k127_5322681_2 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000003949 188.0
HFD1_k127_5322681_3 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000001192 128.0
HFD1_k127_5322681_4 Universal stress protein - - - 0.00000000000002506 79.0
HFD1_k127_5345821_0 response regulator K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 415.0
HFD1_k127_5345821_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000003075 239.0
HFD1_k127_5345821_2 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001312 243.0
HFD1_k127_5362541_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1140.0
HFD1_k127_5362541_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 5.042e-319 1013.0
HFD1_k127_5362541_10 Major facilitator Superfamily K08162,K08226,K16211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 430.0
HFD1_k127_5362541_11 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 399.0
HFD1_k127_5362541_12 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 394.0
HFD1_k127_5362541_13 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 372.0
HFD1_k127_5362541_14 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 376.0
HFD1_k127_5362541_15 tryptophan 2,3-dioxygenase activity K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 352.0
HFD1_k127_5362541_16 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 363.0
HFD1_k127_5362541_17 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 351.0
HFD1_k127_5362541_18 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 312.0
HFD1_k127_5362541_19 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005576 286.0
HFD1_k127_5362541_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.516e-272 858.0
HFD1_k127_5362541_20 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001275 270.0
HFD1_k127_5362541_21 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000001947 226.0
HFD1_k127_5362541_22 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000001807 239.0
HFD1_k127_5362541_23 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000001869 229.0
HFD1_k127_5362541_24 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.0000000000000000000000000000000000000000000000000000007522 214.0
HFD1_k127_5362541_25 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001098 206.0
HFD1_k127_5362541_26 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.00000000000000000000000000000000000000000000001943 192.0
HFD1_k127_5362541_27 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000004488 188.0
HFD1_k127_5362541_28 - - - - 0.00000000000000000000000000000000000000001437 175.0
HFD1_k127_5362541_29 Cytochrome b/b6/petB K00412 - - 0.00000000000000000000000000000000000533 151.0
HFD1_k127_5362541_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 9.211e-246 767.0
HFD1_k127_5362541_30 Endoribonuclease L-PSP - - - 0.00000000000000000000000000001852 130.0
HFD1_k127_5362541_31 Transcriptional regulator - - - 0.000000000000000000000000007043 125.0
HFD1_k127_5362541_32 Protein of unknown function (DUF3365) - - - 0.00000000000000000000002128 113.0
HFD1_k127_5362541_33 COG0723 Rieske Fe-S protein K08355 - 1.20.2.1,1.20.9.1 0.0000000000000005467 83.0
HFD1_k127_5362541_34 receptor K02014 - - 0.000000000000004073 86.0
HFD1_k127_5362541_35 - - - - 0.00000000178 66.0
HFD1_k127_5362541_4 formate dehydrogenase - - - 7.523e-238 760.0
HFD1_k127_5362541_5 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.466e-222 706.0
HFD1_k127_5362541_6 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 548.0
HFD1_k127_5362541_7 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 477.0
HFD1_k127_5362541_8 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 456.0
HFD1_k127_5362541_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 400.0
HFD1_k127_5465276_0 PFAM peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 574.0
HFD1_k127_5465276_1 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.00000000000000000000000000000000001438 138.0
HFD1_k127_5465276_2 DoxX K15977 - - 0.0000000000000000000000000000001845 128.0
HFD1_k127_5505619_0 Highly conserved protein containing a thioredoxin domain K06888 - - 6.043e-241 776.0
HFD1_k127_5505619_1 amine dehydrogenase activity - - - 6.611e-233 756.0
HFD1_k127_5505619_10 PFAM DGPFAETKE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001669 238.0
HFD1_k127_5505619_11 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000000000000000000000000000000000000008113 194.0
HFD1_k127_5505619_12 Doxx family K15977 - - 0.00000000000000000000000000000000000001672 164.0
HFD1_k127_5505619_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000006535 129.0
HFD1_k127_5505619_14 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000001855 141.0
HFD1_k127_5505619_15 Protease prsW family - - - 0.0000000000000000000000000007476 130.0
HFD1_k127_5505619_16 CoA binding domain K06929 - - 0.00000000000000000000000001814 114.0
HFD1_k127_5505619_17 - - - - 0.0000000000000000000000003406 115.0
HFD1_k127_5505619_18 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000001113 122.0
HFD1_k127_5505619_19 Fibronectin type 3 domain - - - 0.0000000000000394 87.0
HFD1_k127_5505619_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 1.614e-194 614.0
HFD1_k127_5505619_20 Tetratricopeptide repeat - - - 0.0000000000007292 79.0
HFD1_k127_5505619_21 antisigma factor binding K04749 - - 0.00000004711 61.0
HFD1_k127_5505619_22 hydrolase (HAD superfamily) K20862 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104 0.0000004252 63.0
HFD1_k127_5505619_23 Histidine kinase-like ATPase domain - - - 0.00001281 55.0
HFD1_k127_5505619_24 Nodulation protein S (NodS) - - - 0.00003226 57.0
HFD1_k127_5505619_3 Magnesium chelatase, subunit ChlI K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 482.0
HFD1_k127_5505619_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 373.0
HFD1_k127_5505619_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 374.0
HFD1_k127_5505619_6 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 379.0
HFD1_k127_5505619_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 320.0
HFD1_k127_5505619_8 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 311.0
HFD1_k127_5505619_9 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 304.0
HFD1_k127_5506868_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 2.051e-214 676.0
HFD1_k127_5506868_1 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 460.0
HFD1_k127_5506868_2 Translation elongation factor K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 482.0
HFD1_k127_5506868_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 430.0
HFD1_k127_5506868_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 403.0
HFD1_k127_5506868_5 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 262.0
HFD1_k127_5506868_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000001294 194.0
HFD1_k127_5506868_7 Binds the 23S rRNA K02909 - - 0.00000000000000000000000009 108.0
HFD1_k127_5506868_8 AAA domain (Cdc48 subfamily) - - - 0.000000000000000007616 98.0
HFD1_k127_5506868_9 TIR domain - - - 0.000375 53.0
HFD1_k127_5532334_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 380.0
HFD1_k127_5532334_1 Neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 349.0
HFD1_k127_5532334_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 340.0
HFD1_k127_5532334_3 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000004274 253.0
HFD1_k127_5532334_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000009232 233.0
HFD1_k127_5532334_5 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000399 214.0
HFD1_k127_5532334_6 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000001681 196.0
HFD1_k127_5532334_7 - - - - 0.000000000000000000000000000271 121.0
HFD1_k127_5532334_8 Dodecin K09165 - - 0.00000000000000000002083 96.0
HFD1_k127_5532334_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000006677 68.0
HFD1_k127_5568477_0 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 486.0
HFD1_k127_5568477_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 464.0
HFD1_k127_5568477_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 432.0
HFD1_k127_5568477_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003019 244.0
HFD1_k127_5568477_5 - - - - 0.00000000011 68.0
HFD1_k127_5568477_6 - - - - 0.00000000483 68.0
HFD1_k127_5568477_7 Helix-turn-helix domain protein - - - 0.00000005847 62.0
HFD1_k127_5568477_9 Tetratricopeptide repeat - - - 0.0008495 51.0
HFD1_k127_5587511_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1264.0
HFD1_k127_5587511_1 Cupredoxin-like domain K00376 - 1.7.2.4 5.149e-225 713.0
HFD1_k127_5587511_10 Cytochrome c - - - 0.0000000000000000009392 100.0
HFD1_k127_5587511_11 SNARE associated Golgi protein - - - 0.00000000008205 72.0
HFD1_k127_5587511_12 Hemerythrin HHE cation binding domain - - - 0.00000121 59.0
HFD1_k127_5587511_2 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 518.0
HFD1_k127_5587511_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 332.0
HFD1_k127_5587511_4 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 308.0
HFD1_k127_5587511_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000001289 231.0
HFD1_k127_5587511_6 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000001053 143.0
HFD1_k127_5587511_7 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000001165 120.0
HFD1_k127_5587511_8 ABC transporter K01990,K19340 - - 0.000000000000000000000002975 112.0
HFD1_k127_5587511_9 Cytochrome c - - - 0.0000000000000000000004273 108.0
HFD1_k127_5607167_0 Uncharacterized protein conserved in bacteria (DUF2330) K00347,K21163 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 544.0
HFD1_k127_5607167_1 Bacterial DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000000000000000000000000000000000000321 150.0
HFD1_k127_5607167_2 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000189 98.0
HFD1_k127_5607167_3 Glyoxalase-like domain K06996 - - 0.00000000000000002193 91.0
HFD1_k127_5607167_4 Domain of unknown function (DU1801) - - - 0.00000000000000007562 90.0
HFD1_k127_5607167_5 DinB family - - - 0.0007951 50.0
HFD1_k127_56073_0 Belongs to the peptidase S1B family - - - 0.0000000000000000000000000000000000000000000000001393 197.0
HFD1_k127_5638383_0 COG0668 Small-conductance mechanosensitive channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 318.0
HFD1_k127_5638383_1 Acetyltransferase (GNAT) domain K03829 - - 0.000000000000000000000000000000000000000000000000000000009236 201.0
HFD1_k127_5638383_2 Ribonuclease, BN K07058 - - 0.0000000000000000000000000000000000000000000000000000001819 205.0
HFD1_k127_5638383_3 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000004818 156.0
HFD1_k127_5638383_4 Pfam:DUF2029 K13671 - - 0.000000402 61.0
HFD1_k127_5644129_0 Peptidase family M3 K01392 - 3.4.24.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 505.0
HFD1_k127_5644129_1 PFAM NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 505.0
HFD1_k127_5644129_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 364.0
HFD1_k127_5644129_3 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001815 270.0
HFD1_k127_5644129_4 Flavin containing amine oxidoreductase K06955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 259.0
HFD1_k127_5644129_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001142 250.0
HFD1_k127_5644129_6 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000003815 184.0
HFD1_k127_5644129_7 - - - - 0.0000000000000000000000000000126 128.0
HFD1_k127_5644129_8 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000006644 118.0
HFD1_k127_5644129_9 Nucleotidyltransferase domain - - - 0.00006231 54.0
HFD1_k127_5709089_0 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 299.0
HFD1_k127_5709089_1 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000556 282.0
HFD1_k127_5709089_2 PFAM M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.00000000000000002379 96.0
HFD1_k127_5709089_3 Glycosyl transferase 4-like domain K03525 - 2.7.1.33 0.0001563 52.0
HFD1_k127_5709920_0 Prokaryotic cytochrome b561 - - - 3.75e-249 786.0
HFD1_k127_5709920_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 6.037e-204 651.0
HFD1_k127_5709920_10 - - - - 0.00004984 51.0
HFD1_k127_5709920_2 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 364.0
HFD1_k127_5709920_3 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001678 294.0
HFD1_k127_5709920_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010269,GO:0010447,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030145,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071291,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000002805 237.0
HFD1_k127_5709920_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000009609 198.0
HFD1_k127_5709920_6 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000000000000000006057 133.0
HFD1_k127_5709920_7 Aminotransferase class-III - - - 0.0000000000000000000000000001294 132.0
HFD1_k127_5709920_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000001174 98.0
HFD1_k127_5741813_0 Malic enzyme, NAD binding domain K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.0 1122.0
HFD1_k127_5741813_1 ABC transporter - - - 1.163e-253 794.0
HFD1_k127_5741813_10 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000001313 89.0
HFD1_k127_5741813_11 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000269 74.0
HFD1_k127_5741813_2 Oxidoreductase - - - 8.029e-223 737.0
HFD1_k127_5741813_3 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 1.071e-215 679.0
HFD1_k127_5741813_4 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 601.0
HFD1_k127_5741813_5 Alanine dehydrogenase/PNT, C-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 514.0
HFD1_k127_5741813_6 fatty acid desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 464.0
HFD1_k127_5741813_7 Glycine cleavage T-protein C-terminal barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 451.0
HFD1_k127_5741813_8 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 394.0
HFD1_k127_5741813_9 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002736 304.0
HFD1_k127_57425_0 ABC transporter - - - 8.155e-260 811.0
HFD1_k127_57425_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 587.0
HFD1_k127_57425_10 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000001547 192.0
HFD1_k127_57425_11 WHG domain - - - 0.000000000000000000000000000000000000000000000000000522 191.0
HFD1_k127_57425_12 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.000000000000000000000000000000000000000007344 156.0
HFD1_k127_57425_13 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000001669 123.0
HFD1_k127_57425_14 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000000000000000118 105.0
HFD1_k127_57425_15 - - - - 0.0000000000000003463 79.0
HFD1_k127_57425_16 BON domain - - - 0.0000000000007389 78.0
HFD1_k127_57425_17 - - - - 0.000000000002237 77.0
HFD1_k127_57425_18 Putative adhesin - - - 0.00000000234 68.0
HFD1_k127_57425_2 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 501.0
HFD1_k127_57425_3 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 409.0
HFD1_k127_57425_4 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 389.0
HFD1_k127_57425_5 Insulinase (Peptidase family M16) K00960,K07263,K07623 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 413.0
HFD1_k127_57425_6 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 309.0
HFD1_k127_57425_7 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001208 264.0
HFD1_k127_57425_8 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000625 217.0
HFD1_k127_57425_9 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000328 197.0
HFD1_k127_5791247_0 Insulinase (Peptidase family M16) K07263 - - 2.06e-287 912.0
HFD1_k127_5791247_1 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 361.0
HFD1_k127_5791247_2 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000001453 190.0
HFD1_k127_5791247_3 Rubrerythrin K22336 - 1.16.3.1 0.000000000000000000000000000000000000000000000001893 179.0
HFD1_k127_5791247_4 DNA restriction-modification system K07317 - 2.1.1.72 0.000000000000000000000000000001067 132.0
HFD1_k127_5791247_5 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000007241 60.0
HFD1_k127_5804700_0 adenosine deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 377.0
HFD1_k127_5804700_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 374.0
HFD1_k127_5804700_2 o-methyltransferase K21377 - 2.1.1.302 0.000000000000000000000000000000002524 141.0
HFD1_k127_5804700_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000005805 126.0
HFD1_k127_5815302_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 419.0
HFD1_k127_5815302_1 transferase activity, transferring glycosyl groups K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 410.0
HFD1_k127_5815302_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 380.0
HFD1_k127_5815302_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 359.0
HFD1_k127_5815302_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 310.0
HFD1_k127_5815302_5 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 310.0
HFD1_k127_5815302_6 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000007522 284.0
HFD1_k127_5815302_7 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000003259 183.0
HFD1_k127_5815302_8 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000007126 162.0
HFD1_k127_5817610_0 Found in ATP-dependent protease La (LON) K01338 - 3.4.21.53 6.991e-207 666.0
HFD1_k127_5817610_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 384.0
HFD1_k127_5817610_2 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 329.0
HFD1_k127_5817610_3 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001645 274.0
HFD1_k127_5817610_4 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000005313 229.0
HFD1_k127_5817610_5 PFAM Abortive infection protein K07052 - - 0.00000000000000000000000000000000003412 147.0
HFD1_k127_5817610_6 PFAM Phosphoglycerate mutase K22305 - 3.1.3.3 0.00000000000000000000000000013 132.0
HFD1_k127_5817610_8 Peptidase, S9A B C family, catalytic domain protein - - - 0.000000000000000000000009392 115.0
HFD1_k127_5817610_9 protein secretion K20276 - - 0.000008299 59.0
HFD1_k127_5824943_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 4.467e-320 1014.0
HFD1_k127_5824943_1 Belongs to the aldehyde dehydrogenase family K22187 - - 8.792e-208 660.0
HFD1_k127_5824943_10 cellulase activity K01201 - 3.2.1.45 0.000000000133 74.0
HFD1_k127_5824943_11 Leishmanolysin - - - 0.00002097 59.0
HFD1_k127_5824943_12 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.0001075 55.0
HFD1_k127_5824943_2 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001833 252.0
HFD1_k127_5824943_3 IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000521 263.0
HFD1_k127_5824943_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000188 233.0
HFD1_k127_5824943_5 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000002503 152.0
HFD1_k127_5824943_6 PFAM Integrase, catalytic - - - 0.000000000000000000000002243 106.0
HFD1_k127_5824943_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000101 94.0
HFD1_k127_5824943_8 Belongs to the peptidase S8 family - - - 0.0000000000005483 80.0
HFD1_k127_5824943_9 IstB domain protein ATP-binding protein - - - 0.00000000003119 71.0
HFD1_k127_5826946_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 590.0
HFD1_k127_5826946_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000004476 235.0
HFD1_k127_5826946_2 - - - - 0.000000000000000000000000000000000000000000000000000000001483 208.0
HFD1_k127_5826946_3 Indolepyruvate K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000002589 215.0
HFD1_k127_5826946_4 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000002754 170.0
HFD1_k127_5826946_5 - - - - 0.00001702 55.0
HFD1_k127_5839115_0 Ribosomal protein S1 K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 399.0
HFD1_k127_5839115_1 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 315.0
HFD1_k127_5839115_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000001821 89.0
HFD1_k127_5839115_3 Sporulation related domain K03749 - - 0.0002185 54.0
HFD1_k127_5892674_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 602.0
HFD1_k127_5892674_1 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 312.0
HFD1_k127_5892674_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001303 295.0
HFD1_k127_5892674_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000006256 243.0
HFD1_k127_5892674_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000003734 158.0
HFD1_k127_5892674_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000001352 102.0
HFD1_k127_5892674_6 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000008746 96.0
HFD1_k127_5892674_7 Ribosomal protein L34 K02914 - - 0.000000000003149 67.0
HFD1_k127_5892674_8 single-stranded nucleic acid binding R3H K06346 - - 0.00000000001004 75.0
HFD1_k127_5892674_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000008855 65.0
HFD1_k127_5902475_0 PFAM RNA polymerase sigma factor 54, interaction - - - 2.424e-236 750.0
HFD1_k127_5902475_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000357 265.0
HFD1_k127_5902475_2 PFAM nuclease (SNase domain protein) K01174 - 3.1.31.1 0.00000000000000000004804 98.0
HFD1_k127_5902475_3 Cupin domain - - - 0.0004015 52.0
HFD1_k127_5917185_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 3291.0
HFD1_k127_5917185_1 lysine 2,3-aminomutase - - - 1.702e-232 732.0
HFD1_k127_5917185_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 324.0
HFD1_k127_5917185_3 - - - - 0.00000000000001036 75.0
HFD1_k127_5917185_4 - - - - 0.0000000000003451 73.0
HFD1_k127_5917185_5 Peptidase_C39 like family - - - 0.00000000001802 78.0
HFD1_k127_5926245_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.361e-246 778.0
HFD1_k127_5926245_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 387.0
HFD1_k127_5926245_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000001108 157.0
HFD1_k127_5944378_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412,K13491 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 338.0
HFD1_k127_5944378_1 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001346 278.0
HFD1_k127_5944378_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002856 281.0
HFD1_k127_5944378_3 response regulator receiver K03413 - - 0.00000000000000000000000000000001029 136.0
HFD1_k127_5944378_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K03406 - - 0.0007066 46.0
HFD1_k127_5948308_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 428.0
HFD1_k127_5948308_1 TIGRFAM Bacterial surface protein 26-residue repeat - - - 0.0000000000000000000000000000000003216 148.0
HFD1_k127_5948308_2 PA14 domain - - - 0.00000000001166 77.0
HFD1_k127_5948308_3 extracellular matrix structural constituent - - - 0.00000000001545 77.0
HFD1_k127_5948308_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000002508 64.0
HFD1_k127_5984133_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.933e-255 817.0
HFD1_k127_5984133_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 453.0
HFD1_k127_5984133_10 Belongs to the UPF0109 family K06960 - - 0.000000000000002984 83.0
HFD1_k127_5984133_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000395 252.0
HFD1_k127_5984133_3 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000306 203.0
HFD1_k127_5984133_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000183 201.0
HFD1_k127_5984133_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002764 142.0
HFD1_k127_5984133_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000001387 125.0
HFD1_k127_5984133_7 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000008083 112.0
HFD1_k127_5984133_8 Belongs to the UPF0102 family K07460 - - 0.00000000000000005932 87.0
HFD1_k127_5984133_9 Chemotaxis protein CheY K02490 - - 0.000000000000001044 82.0
HFD1_k127_6026880_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 425.0
HFD1_k127_6026880_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000002117 199.0
HFD1_k127_6026880_2 sulfuric ester hydrolase activity K03760,K06349,K19353 GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 2.7.8.43 0.0000000000000000000000000000000000000000000004992 177.0
HFD1_k127_6026880_3 AAA domain - - - 0.0000000000000000000000000000000000002653 148.0
HFD1_k127_6026880_4 DNA excision K02806 - - 0.000000000000001732 88.0
HFD1_k127_6072311_0 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001394 286.0
HFD1_k127_6072311_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000004169 191.0
HFD1_k127_6072311_2 Protein of unknown function (DUF1326) - - - 0.00000000000005435 76.0
HFD1_k127_6072311_3 DUF167 K09131 - - 0.0000000000004547 74.0
HFD1_k127_6072311_4 PFAM Membrane protein of K08972 - - 0.0000000002106 68.0
HFD1_k127_6112574_0 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007742 267.0
HFD1_k127_6112574_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 249.0
HFD1_k127_6112574_2 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000008987 143.0
HFD1_k127_6112574_3 - - - - 0.00000000000000000000008074 111.0
HFD1_k127_6112574_4 Predicted permease K07089 - - 0.00000000000000000000008622 113.0
HFD1_k127_6112574_5 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000123 52.0
HFD1_k127_6122439_0 type II secretion system protein K02243,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 490.0
HFD1_k127_6122439_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 429.0
HFD1_k127_6122439_2 Type II secretory pathway component PulF K02505,K12278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004178 290.0
HFD1_k127_6122439_3 5'-nucleotidase - - - 0.0000000000000000000000000000000000000000000000328 184.0
HFD1_k127_6122439_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000002285 102.0
HFD1_k127_6122439_5 Transmembrane protein 260 - - - 0.0000000000000000009941 99.0
HFD1_k127_6122439_6 Prokaryotic N-terminal methylation motif - - - 0.0000000000005092 75.0
HFD1_k127_6161675_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 7.868e-238 747.0
HFD1_k127_6161675_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008112 616.0
HFD1_k127_6161675_2 PFAM Carbamoyl-phosphate synthase L chain, ATP binding K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 490.0
HFD1_k127_6161675_3 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000006013 193.0
HFD1_k127_6161675_4 PFAM thioesterase superfamily - - - 0.0000000000000000000000003025 113.0
HFD1_k127_6161675_5 carboxylase K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000008915 68.0
HFD1_k127_6262396_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 549.0
HFD1_k127_6262396_1 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 355.0
HFD1_k127_6262396_2 Glycosyl transferases group 1 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 314.0
HFD1_k127_6262396_3 Peptidogalycan biosysnthesis/recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000137 305.0
HFD1_k127_6262396_4 PFAM Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000811 278.0
HFD1_k127_6262396_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000006418 205.0
HFD1_k127_6262396_6 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000007435 187.0
HFD1_k127_6262396_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000004497 194.0
HFD1_k127_6262396_8 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000006984 136.0
HFD1_k127_6262396_9 Capsular exopolysaccharide family - - - 0.00000000008379 67.0
HFD1_k127_6275093_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 373.0
HFD1_k127_6275093_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000001382 172.0
HFD1_k127_6314753_0 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 546.0
HFD1_k127_6314753_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 524.0
HFD1_k127_6314753_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 389.0
HFD1_k127_6314753_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 260.0
HFD1_k127_6314753_4 PFAM Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000009148 87.0
HFD1_k127_6328007_0 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K20997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 355.0
HFD1_k127_6328007_1 Cephalosporin hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002932 250.0
HFD1_k127_6328007_2 Protein conserved in bacteria K06320 - - 0.0000000000000000000000000000002193 139.0
HFD1_k127_6328007_3 transferase activity, transferring glycosyl groups - - - 0.00000000000002504 81.0
HFD1_k127_6328007_4 O-Antigen ligase - - - 0.00005465 55.0
HFD1_k127_6336709_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 428.0
HFD1_k127_6336709_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000009274 95.0
HFD1_k127_6336709_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000001692 101.0
HFD1_k127_6336709_3 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000002894 100.0
HFD1_k127_6336709_4 Acetyltransferase (GNAT) domain - - - 0.000000007483 64.0
HFD1_k127_6336709_5 -acetyltransferase - - - 0.000007496 58.0
HFD1_k127_6337329_0 Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 341.0
HFD1_k127_6337329_1 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000008039 259.0
HFD1_k127_6337329_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.0000000000000000000000000000000000000000000000000000003194 202.0
HFD1_k127_6337329_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000004759 196.0
HFD1_k127_6337329_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000141 184.0
HFD1_k127_6337329_5 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000104 165.0
HFD1_k127_6337329_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000001736 72.0
HFD1_k127_6347442_0 Glycosyltransferase family 20 K16055 - 2.4.1.15,3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 424.0
HFD1_k127_6347442_1 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000003135 121.0
HFD1_k127_6382526_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 423.0
HFD1_k127_6382526_1 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 379.0
HFD1_k127_6440347_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 492.0
HFD1_k127_6440347_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 330.0
HFD1_k127_6440347_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000007613 210.0
HFD1_k127_6440347_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000001344 110.0
HFD1_k127_6499503_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.112e-220 697.0
HFD1_k127_6499503_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 401.0
HFD1_k127_6499503_10 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000021 124.0
HFD1_k127_6499503_11 Lipopolysaccharide-assembly, LptC-related K09774,K11719 - - 0.00000000000000000000000004197 118.0
HFD1_k127_6499503_12 PTS system sorbose subfamily IIB component K19507 - - 0.0000000000000000000000001683 113.0
HFD1_k127_6499503_13 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000001463 83.0
HFD1_k127_6499503_14 system, fructose subfamily IIA component K02793,K02794 - 2.7.1.191 0.00000000002012 70.0
HFD1_k127_6499503_15 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000004227 59.0
HFD1_k127_6499503_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 373.0
HFD1_k127_6499503_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 339.0
HFD1_k127_6499503_4 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 308.0
HFD1_k127_6499503_5 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 304.0
HFD1_k127_6499503_6 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001477 287.0
HFD1_k127_6499503_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000002323 221.0
HFD1_k127_6499503_8 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000007137 219.0
HFD1_k127_6499503_9 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000001669 149.0
HFD1_k127_6517064_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.498e-305 949.0
HFD1_k127_6517064_1 PFAM Peptidase M16 K07263 - - 8.874e-261 825.0
HFD1_k127_6517064_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 5.413e-237 745.0
HFD1_k127_6517064_3 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003367 271.0
HFD1_k127_6517064_4 crp fnr family K01420 - - 0.00000000000000000000000000000000000000000000000000007421 195.0
HFD1_k127_6517064_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000003935 207.0
HFD1_k127_6623814_0 FAD-NAD(P)-binding K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 330.0
HFD1_k127_6623814_1 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 309.0
HFD1_k127_6623814_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000871 216.0
HFD1_k127_6623814_3 Lamin Tail Domain - - - 0.000000005052 59.0
HFD1_k127_6641552_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000003913 98.0
HFD1_k127_6647592_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 425.0
HFD1_k127_6647592_1 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000001381 254.0
HFD1_k127_6647592_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000001896 216.0
HFD1_k127_6647592_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000002937 163.0
HFD1_k127_6687525_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 586.0
HFD1_k127_6687525_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 582.0
HFD1_k127_6687525_10 Capsule assembly protein Wzi - - - 0.0000000000006674 81.0
HFD1_k127_6687525_11 FeoA K04758 - - 0.000000000003078 76.0
HFD1_k127_6687525_12 hyperosmotic response - - - 0.00000000001058 75.0
HFD1_k127_6687525_13 pectinesterase activity K10117 - - 0.000000063 67.0
HFD1_k127_6687525_2 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 353.0
HFD1_k127_6687525_3 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 346.0
HFD1_k127_6687525_4 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007722 246.0
HFD1_k127_6687525_5 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000004405 251.0
HFD1_k127_6687525_6 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000003368 181.0
HFD1_k127_6687525_7 - - - - 0.000000000000000000000000000000000000000000000000454 181.0
HFD1_k127_6687525_8 CARDB - - - 0.0000000000000000000002102 115.0
HFD1_k127_6687525_9 Iron (Metal) dependent repressor, DtxR family - - - 0.000000000000000000001023 102.0
HFD1_k127_6688144_0 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 353.0
HFD1_k127_6688144_1 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 345.0
HFD1_k127_6688144_2 sequence-specific DNA binding - - - 0.0000000000000000000000000000000004668 142.0
HFD1_k127_6713113_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 477.0
HFD1_k127_6713113_1 Erythromycin esterase K06880 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 403.0
HFD1_k127_6713113_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 296.0
HFD1_k127_6731398_0 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 375.0
HFD1_k127_6731398_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000001706 256.0
HFD1_k127_6731398_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000005189 165.0
HFD1_k127_6731398_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000008302 113.0
HFD1_k127_6731398_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000008857 106.0
HFD1_k127_6731398_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K01808,K07566,K20201 - 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 0.000000000000000000006871 98.0
HFD1_k127_68245_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 405.0
HFD1_k127_68245_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000004901 239.0
HFD1_k127_6830819_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 4.175e-194 632.0
HFD1_k127_6830819_1 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 364.0
HFD1_k127_6830819_10 Putative zinc-finger - - - 0.0008277 52.0
HFD1_k127_6830819_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000004782 248.0
HFD1_k127_6830819_3 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000266 188.0
HFD1_k127_6830819_4 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000001333 131.0
HFD1_k127_6830819_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000005874 85.0
HFD1_k127_6830819_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000002799 84.0
HFD1_k127_6830819_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000005662 77.0
HFD1_k127_6830819_8 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000007864 73.0
HFD1_k127_6830819_9 proton-transporting ATP synthase activity, rotational mechanism K02137 GO:0000275,GO:0000276,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005756,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0007275,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008289,GO:0008340,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0010259,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0022857,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0033177,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042407,GO:0042776,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044877,GO:0045259,GO:0045261,GO:0045263,GO:0045269,GO:0046034,GO:0046390,GO:0046483,GO:0046907,GO:0048856,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0055086,GO:0061024,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1990542 - 0.00000000005157 74.0
HFD1_k127_6881689_0 Peptidase family M1 domain K01992 - - 2.594e-221 726.0
HFD1_k127_6881689_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 434.0
HFD1_k127_6881689_2 (ABC) transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 397.0
HFD1_k127_6881689_3 Phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000005357 158.0
HFD1_k127_6881689_4 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.000000000000000000000000000000000001385 145.0
HFD1_k127_6881689_5 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.0000000000000000000000000000000002583 135.0
HFD1_k127_6896550_0 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 360.0
HFD1_k127_6896550_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 295.0
HFD1_k127_6896550_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002257 264.0
HFD1_k127_6896550_3 - - - - 0.0000000000000000000000000001901 128.0
HFD1_k127_6896550_4 YceI-like domain - - - 0.000000000000000000000001152 112.0
HFD1_k127_6896550_5 fatty acid transporter K02106 - - 0.00000000000000000001992 98.0
HFD1_k127_6896550_6 Evidence 5 No homology to any previously reported sequences K03088 - - 0.00000000001617 77.0
HFD1_k127_6945091_0 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000003565 238.0
HFD1_k127_6945091_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000004797 171.0
HFD1_k127_6945091_2 CTP synthase K01937 - 6.3.4.2 0.00000000000000000000000000001398 123.0
HFD1_k127_6945091_3 CTP synthase K01937 - 6.3.4.2 0.00000000000562 77.0
HFD1_k127_6945091_4 - - - - 0.000001397 56.0
HFD1_k127_6945091_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0005016 42.0
HFD1_k127_6975499_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 623.0
HFD1_k127_6975499_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 294.0
HFD1_k127_6975499_2 DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
HFD1_k127_6975499_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001552 245.0
HFD1_k127_6975499_4 sAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000006222 223.0
HFD1_k127_6975499_5 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000004416 238.0
HFD1_k127_6975499_6 RNase_H superfamily K07502 - - 0.00000000000000000000000000000001342 148.0
HFD1_k127_6975499_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000005991 84.0
HFD1_k127_7049512_0 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 9.242e-230 728.0
HFD1_k127_7049512_1 Acetokinase family K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004202 310.0
HFD1_k127_7057272_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 578.0
HFD1_k127_7057272_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 425.0
HFD1_k127_7057272_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000008887 168.0
HFD1_k127_7057272_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000393 115.0
HFD1_k127_7092775_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 5.211e-246 777.0
HFD1_k127_7092775_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 441.0
HFD1_k127_7092775_10 PFAM Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000008654 149.0
HFD1_k127_7092775_11 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000001609 138.0
HFD1_k127_7092775_12 oligosaccharyl transferase activity - - - 0.000000000000000000000000000004818 138.0
HFD1_k127_7092775_13 methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000002941 137.0
HFD1_k127_7092775_14 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000003356 136.0
HFD1_k127_7092775_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.00000000000000000000000000004958 135.0
HFD1_k127_7092775_16 Putative regulatory protein - - - 0.000000000000000000000002759 107.0
HFD1_k127_7092775_17 Protein of unknown function (DUF3467) - - - 0.0000000000000000000004 113.0
HFD1_k127_7092775_18 Pilus assembly protein, PilO K02664 - - 0.000000000000000000001056 102.0
HFD1_k127_7092775_19 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000002899 102.0
HFD1_k127_7092775_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 394.0
HFD1_k127_7092775_20 - - - - 0.0000000000008515 78.0
HFD1_k127_7092775_21 PFAM Fimbrial assembly family protein K02662,K02663 - - 0.00000000000552 74.0
HFD1_k127_7092775_23 HEAT repeat - - - 0.0005077 53.0
HFD1_k127_7092775_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 346.0
HFD1_k127_7092775_4 Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 355.0
HFD1_k127_7092775_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 293.0
HFD1_k127_7092775_6 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002215 275.0
HFD1_k127_7092775_7 Type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001813 274.0
HFD1_k127_7092775_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000007083 180.0
HFD1_k127_7092775_9 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000004113 160.0
HFD1_k127_709724_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 501.0
HFD1_k127_709724_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 342.0
HFD1_k127_709724_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 304.0
HFD1_k127_709724_3 Bacterial regulatory protein, Fis family K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 284.0
HFD1_k127_709724_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006006 275.0
HFD1_k127_709724_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006195 264.0
HFD1_k127_709724_6 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008628 236.0
HFD1_k127_709724_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000001326 121.0
HFD1_k127_709724_8 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000001741 63.0
HFD1_k127_7098594_0 Carbamoyltransferase C-terminus K00612 - - 2.729e-277 865.0
HFD1_k127_7098594_1 PFAM nuclease (SNase K01174 - 3.1.31.1 0.00000000000000000009581 98.0
HFD1_k127_7098594_2 - - - - 0.00000000002571 67.0
HFD1_k127_7098594_3 - - - - 0.000005372 60.0
HFD1_k127_7098594_4 Cupin domain - - - 0.00003556 54.0
HFD1_k127_7225704_0 ERAP1-like C-terminal domain K01256,K01263 - 3.4.11.14,3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 558.0
HFD1_k127_7225704_1 - - - - 0.0000000342 56.0
HFD1_k127_7225704_2 - - - - 0.00008754 53.0
HFD1_k127_7243908_0 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA - - - 2.533e-280 881.0
HFD1_k127_7243908_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 426.0
HFD1_k127_7243908_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 356.0
HFD1_k127_7243908_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000002256 159.0
HFD1_k127_7243908_4 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000577 97.0
HFD1_k127_7243908_5 Prepilin-type N-terminal cleavage methylation domain K02456,K02650 - - 0.00000000004052 71.0
HFD1_k127_7243908_6 Peptidase m28 - - - 0.00000009246 55.0
HFD1_k127_7243908_7 Fibronectin type 3 domain - - - 0.000001129 62.0
HFD1_k127_7260203_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 492.0
HFD1_k127_7260203_1 PFAM Bile acid sodium symporter K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000000002601 244.0
HFD1_k127_7260203_2 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000004933 224.0
HFD1_k127_7260203_3 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000001404 200.0
HFD1_k127_7260203_4 Peptidase family M23 K01406 - 3.4.24.40 0.0000000000000000000000000000000003845 151.0
HFD1_k127_7260203_5 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000001644 115.0
HFD1_k127_7260203_6 - - - - 0.00000000000000000000001495 115.0
HFD1_k127_7260203_7 Domain of unknown function (DUF3943) - - - 0.000000000000000000000794 99.0
HFD1_k127_7260203_8 - - - - 0.0008007 44.0
HFD1_k127_7264019_0 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 501.0
HFD1_k127_7264019_1 Uncharacterized protein conserved in bacteria (DUF2330) K00347,K21163 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 317.0
HFD1_k127_7264019_2 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000005386 231.0
HFD1_k127_7264019_3 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000002884 222.0
HFD1_k127_7264019_4 Homocysteine S-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000005194 202.0
HFD1_k127_7264019_5 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000001725 211.0
HFD1_k127_7264019_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000002834 191.0
HFD1_k127_7264019_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000006427 155.0
HFD1_k127_7272594_0 nitronate monooxygenase activity K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 317.0
HFD1_k127_7272594_1 - - - - 0.00000000000000000000000000000000000000000000001257 192.0
HFD1_k127_7272594_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000001094 102.0
HFD1_k127_7302365_0 PFAM sigma-54 factor interaction domain-containing protein K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 405.0
HFD1_k127_7302365_1 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000673 167.0
HFD1_k127_7302365_2 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000111 135.0
HFD1_k127_7302365_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000567 123.0
HFD1_k127_7302365_4 Bacterial protein of unknown function (DUF885) - - - 0.000000000000002696 89.0
HFD1_k127_7370350_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 439.0
HFD1_k127_7370350_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001594 289.0
HFD1_k127_7370350_2 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000001149 207.0
HFD1_k127_7370350_3 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000001362 194.0
HFD1_k127_7370350_4 response regulator receiver K02481,K07713 - - 0.00000000000000000003827 100.0
HFD1_k127_7370350_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000005769 79.0
HFD1_k127_7370350_6 - - - - 0.00000000004749 64.0
HFD1_k127_7371288_0 transcription factor binding K02584 - - 1.882e-219 692.0
HFD1_k127_7371288_1 Berberine and berberine like - - - 8.075e-219 688.0
HFD1_k127_7371288_2 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 379.0
HFD1_k127_7371288_3 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000003165 222.0
HFD1_k127_7371288_4 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000002129 184.0
HFD1_k127_7371288_5 monooxygenase activity - - - 0.00000000000000000000000000000001682 136.0
HFD1_k127_7371288_6 COG0666 FOG Ankyrin repeat - - - 0.0000000000003856 76.0
HFD1_k127_7371288_7 PFAM Bacterial regulatory protein, Fis family - - - 0.000003133 55.0
HFD1_k127_7371288_8 Glycosyltransferase family 87 K13671 - - 0.00001515 57.0
HFD1_k127_7377681_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 396.0
HFD1_k127_7377681_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 311.0
HFD1_k127_7377681_2 MFS_1 like family K08161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 298.0
HFD1_k127_7377681_3 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000007671 199.0
HFD1_k127_7377681_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000002946 183.0
HFD1_k127_7377681_5 - - - - 0.0000000000000000000000000000000000000000001396 179.0
HFD1_k127_7377681_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000001342 116.0
HFD1_k127_7391980_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 304.0
HFD1_k127_7391980_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000002044 213.0
HFD1_k127_7391980_2 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.000000000000000000000000000000000000000000000000005677 198.0
HFD1_k127_7391980_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000002452 182.0
HFD1_k127_7391980_4 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000001664 167.0
HFD1_k127_7391980_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000006656 163.0
HFD1_k127_7391980_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000893 109.0
HFD1_k127_7391980_7 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.0000000000009878 78.0
HFD1_k127_7391980_8 Peptidase, M23 family - - - 0.0000001265 64.0
HFD1_k127_7442590_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.279e-250 840.0
HFD1_k127_7442590_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 431.0
HFD1_k127_7442590_10 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000001593 133.0
HFD1_k127_7442590_11 Part of the ABC transporter FtsEX involved in K09811 - - 0.0000000000000000000296 102.0
HFD1_k127_7442590_12 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000002635 55.0
HFD1_k127_7442590_13 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0003463 53.0
HFD1_k127_7442590_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 327.0
HFD1_k127_7442590_3 PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001457 252.0
HFD1_k127_7442590_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000003348 248.0
HFD1_k127_7442590_5 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000003764 223.0
HFD1_k127_7442590_6 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000002777 224.0
HFD1_k127_7442590_7 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000001664 177.0
HFD1_k127_7442590_8 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000002459 173.0
HFD1_k127_7442590_9 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000001943 155.0
HFD1_k127_7460707_0 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 351.0
HFD1_k127_7460707_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
HFD1_k127_7460707_2 sequence-specific DNA binding K03719 - - 0.00000000000000000000000000000000000000000000000009262 182.0
HFD1_k127_7460707_3 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000001047 153.0
HFD1_k127_7460707_4 - - - - 0.000000000000000000000000000000551 126.0
HFD1_k127_7460707_5 extracellular matrix structural constituent - - - 0.00000000002648 70.0
HFD1_k127_7522493_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 299.0
HFD1_k127_7522493_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001137 236.0
HFD1_k127_7522493_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000001941 232.0
HFD1_k127_7522493_3 Transglycosylase associated protein - - - 0.00000000000000000000001069 104.0
HFD1_k127_7522493_4 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000005862 100.0
HFD1_k127_7566118_0 BadF BadG BcrA BcrD - - - 1.586e-269 883.0
HFD1_k127_7566118_1 Carbamoyltransferase C-terminus K00612,K16035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 419.0
HFD1_k127_7566118_10 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.00000000002971 74.0
HFD1_k127_7566118_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 340.0
HFD1_k127_7566118_3 HAD-superfamily phosphatase, subfamily IIIC K16027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001621 257.0
HFD1_k127_7566118_4 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000002217 264.0
HFD1_k127_7566118_5 PFAM Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000001173 194.0
HFD1_k127_7566118_6 PFAM Diacylglycerol kinase, catalytic K07029 - 2.7.1.107 0.00000000000000000000000000000000000000000000001664 182.0
HFD1_k127_7566118_7 Chalcone isomerase-like - - - 0.00000000000000000000000000003906 124.0
HFD1_k127_7566118_8 methyltransferase - - - 0.000000000000001601 91.0
HFD1_k127_7566118_9 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000005993 87.0
HFD1_k127_7579012_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.125e-303 951.0
HFD1_k127_7579012_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000003619 173.0
HFD1_k127_7797305_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.157e-198 645.0
HFD1_k127_7797305_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 371.0
HFD1_k127_7797305_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 367.0
HFD1_k127_7797305_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000001687 206.0
HFD1_k127_7797305_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000003707 57.0
HFD1_k127_7797305_5 OmpW family K07275 - - 0.0009113 50.0
HFD1_k127_7806402_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.335e-236 746.0
HFD1_k127_7806402_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 378.0
HFD1_k127_7806402_2 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 357.0
HFD1_k127_7806402_3 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000008093 239.0
HFD1_k127_7806402_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000002564 218.0
HFD1_k127_7806402_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000002876 197.0
HFD1_k127_7806402_6 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000005001 148.0
HFD1_k127_7806402_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000002994 132.0
HFD1_k127_7806402_8 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000001662 98.0
HFD1_k127_7825271_0 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 586.0
HFD1_k127_7825271_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 439.0
HFD1_k127_7825271_10 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.000000000006326 76.0
HFD1_k127_7825271_11 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.00001288 59.0
HFD1_k127_7825271_12 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K04040 - 2.5.1.133,2.5.1.39,2.5.1.62 0.0002304 51.0
HFD1_k127_7825271_2 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000003012 233.0
HFD1_k127_7825271_3 PFAM Biopolymer transport protein ExbD TolR - - - 0.0000000000000000000000000000000003015 138.0
HFD1_k127_7825271_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000002087 125.0
HFD1_k127_7825271_5 PBP superfamily domain K02040 - - 0.000000000000000000000002056 114.0
HFD1_k127_7825271_6 Outer membrane transport energization protein ExbD - - - 0.000000000000000000000002368 107.0
HFD1_k127_7825271_7 Tetratricopeptide repeat - - - 0.0000000000000000000001463 113.0
HFD1_k127_7825271_8 adventurous gliding protein T - - - 0.000000000000006634 89.0
HFD1_k127_7825271_9 STAS domain K04749 - - 0.000000000003925 72.0
HFD1_k127_7884426_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 432.0
HFD1_k127_7884426_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 368.0
HFD1_k127_7884426_2 FeS-containing Cyanobacterial-specific oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 346.0
HFD1_k127_7884426_3 PFAM peptidase M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 318.0
HFD1_k127_7884426_4 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 319.0
HFD1_k127_7884426_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000001612 228.0
HFD1_k127_7884426_6 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0000000000000000000000000000000000007091 147.0
HFD1_k127_7884426_7 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591,K22491 - - 0.000000000000000000004677 99.0
HFD1_k127_7884426_8 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000188 61.0
HFD1_k127_7884426_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0005913 44.0
HFD1_k127_7932033_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000122 183.0
HFD1_k127_7932033_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000235 163.0
HFD1_k127_7932033_2 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000001203 131.0
HFD1_k127_7932033_3 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000003967 115.0
HFD1_k127_7932033_4 Cold-shock protein K03704 - - 0.0000000000000000001292 91.0
HFD1_k127_796761_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 385.0
HFD1_k127_796761_1 EamA-like transporter family - - - 0.000000000000000000000000000001327 133.0
HFD1_k127_796761_2 - - - - 0.000001165 58.0
HFD1_k127_8023738_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.146e-229 722.0
HFD1_k127_8023738_1 Coenzyme A transferase K01027,K01028,K01034 - 2.8.3.5,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 345.0
HFD1_k127_8023738_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 346.0
HFD1_k127_8023738_3 isobutyryl-CoA mutase activity K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000902 271.0
HFD1_k127_8023738_4 Monogalactosyldiacylglycerol (MGDG) synthase K03429,K03715 - 2.4.1.315,2.4.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000004762 254.0
HFD1_k127_8023738_5 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000005053 203.0
HFD1_k127_8023738_6 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000006051 195.0
HFD1_k127_815748_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1230.0
HFD1_k127_815748_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.677e-303 953.0
HFD1_k127_815748_2 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000001353 229.0
HFD1_k127_815748_3 B12 binding domain K22491 - - 0.000000000000000003337 89.0
HFD1_k127_832035_0 imidazolonepropionase activity K00466 - 1.13.12.3 0.0000000000000000000000001894 119.0
HFD1_k127_832035_1 NmrA-like family - - - 0.00000000000000000009771 102.0
HFD1_k127_832035_2 PFAM BioY protein K03523 - - 0.00006125 48.0
HFD1_k127_867532_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 427.0
HFD1_k127_867532_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 394.0
HFD1_k127_867532_2 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003507 274.0
HFD1_k127_867532_3 Hypothetical methyltransferase - - - 0.000001088 60.0
HFD1_k127_954558_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 514.0
HFD1_k127_954558_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
HFD1_k127_972438_0 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 400.0
HFD1_k127_972438_1 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 293.0
HFD1_k127_972438_2 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000001325 270.0
HFD1_k127_972438_3 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000002714 188.0
HFD1_k127_972438_4 pyridine nucleotide-disulfide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000008927 189.0
HFD1_k127_972438_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000009651 158.0
HFD1_k127_972438_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000001294 124.0
HFD1_k127_972438_7 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000004813 103.0
HFD1_k127_972438_8 - - - - 0.000007988 59.0
HFD1_k127_987517_0 MutL protein K00854 - 2.7.1.17 2.214e-269 847.0
HFD1_k127_987517_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 286.0
HFD1_k127_987517_2 - - - - 0.00000000000000000000549 98.0
HFD1_k127_987517_3 - - - - 0.0000004637 59.0