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Overview

ID MAG01618
Name HFD1_bin.27
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order Pyrinomonadales
Family Pyrinomonadaceae
Genus UBA11740
Species UBA11740 sp035469005
Assembly information
Completeness (%) 93.4
Contamination (%) 0.3
GC content (%) 55.0
N50 (bp) 37,230
Genome size (bp) 5,790,324

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4314

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1002298_0 A-macroglobulin receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 470.0
HFD1_k127_1002298_1 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 407.0
HFD1_k127_1002298_2 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 321.0
HFD1_k127_1002298_3 Threonine alanine tRNA ligase second additional domain protein K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004344 287.0
HFD1_k127_1002298_4 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000004332 196.0
HFD1_k127_1002298_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000002596 182.0
HFD1_k127_101186_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.004e-222 717.0
HFD1_k127_101186_1 Transposase IS200 like - - - 0.0004131 46.0
HFD1_k127_1022818_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 454.0
HFD1_k127_1022818_1 cellulose binding - - - 0.00000000000000000000000000002788 121.0
HFD1_k127_1022818_2 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000003827 59.0
HFD1_k127_1027090_0 (ABC) transporter K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 5.365e-300 926.0
HFD1_k127_1027090_1 PFAM Prolyl oligopeptidase family - - - 6.362e-286 891.0
HFD1_k127_1027090_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 415.0
HFD1_k127_1027090_11 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 408.0
HFD1_k127_1027090_12 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 397.0
HFD1_k127_1027090_13 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 316.0
HFD1_k127_1027090_14 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002597 269.0
HFD1_k127_1027090_15 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000009474 227.0
HFD1_k127_1027090_16 - - - - 0.00000000000000000000000000000000000000000000000000000000001753 217.0
HFD1_k127_1027090_17 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000001666 203.0
HFD1_k127_1027090_18 Belongs to the sulfate adenylyltransferase family K00958 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 2.7.7.4 0.00000000000000000000000000000000000000000000000002524 194.0
HFD1_k127_1027090_19 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000006644 173.0
HFD1_k127_1027090_2 N-acetyldiaminopimelate deacetylase activity K12941 - - 5.388e-238 745.0
HFD1_k127_1027090_20 Transposase K07491 - - 0.00000000000000000000000000000000001344 141.0
HFD1_k127_1027090_21 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000002321 146.0
HFD1_k127_1027090_22 - - - - 0.000000000000000000000000004124 123.0
HFD1_k127_1027090_23 Catalyzes the synthesis of activated sulfate - - - 0.000000000000000000000006194 115.0
HFD1_k127_1027090_24 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000000000009384 81.0
HFD1_k127_1027090_26 Protein conserved in bacteria - - - 0.00000000000006975 78.0
HFD1_k127_1027090_27 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000009398 71.0
HFD1_k127_1027090_3 Hydrolase CocE NonD family - - - 1.649e-220 691.0
HFD1_k127_1027090_4 hydrolase activity, hydrolyzing O-glycosyl compounds K00689 GO:0005575,GO:0005576 2.4.1.5 2.094e-194 623.0
HFD1_k127_1027090_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 621.0
HFD1_k127_1027090_6 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 605.0
HFD1_k127_1027090_7 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 565.0
HFD1_k127_1027090_8 oligopeptide transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 537.0
HFD1_k127_1027090_9 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 458.0
HFD1_k127_1027733_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1738.0
HFD1_k127_1027733_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1149.0
HFD1_k127_1027733_10 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 452.0
HFD1_k127_1027733_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 419.0
HFD1_k127_1027733_12 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 409.0
HFD1_k127_1027733_13 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 395.0
HFD1_k127_1027733_14 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 321.0
HFD1_k127_1027733_15 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 319.0
HFD1_k127_1027733_16 Domain of unknown function (DUF1858) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 312.0
HFD1_k127_1027733_17 4 iron, 4 sulfur cluster binding K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 296.0
HFD1_k127_1027733_18 Domain of Unknown function (DUF542) K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000000007284 239.0
HFD1_k127_1027733_19 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.00000000000000000000000000000000000000000000000000000000006991 209.0
HFD1_k127_1027733_2 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 595.0
HFD1_k127_1027733_20 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000002293 196.0
HFD1_k127_1027733_21 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000000000301 192.0
HFD1_k127_1027733_22 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000000003358 182.0
HFD1_k127_1027733_23 - - - - 0.000000000000000000000000000000000000000000000003132 197.0
HFD1_k127_1027733_24 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000002215 170.0
HFD1_k127_1027733_25 PFAM glycine cleavage H-protein - - - 0.00000000000000000000000000000000003142 145.0
HFD1_k127_1027733_26 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000003142 139.0
HFD1_k127_1027733_27 response to abiotic stimulus - - - 0.000000000000000000000000000004239 136.0
HFD1_k127_1027733_29 Glycine cleavage H-protein - - - 0.000000000000000000000000002126 120.0
HFD1_k127_1027733_3 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 566.0
HFD1_k127_1027733_30 Universal stress protein family - - - 0.00000000000000000000000009952 114.0
HFD1_k127_1027733_31 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000003473 102.0
HFD1_k127_1027733_32 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.00000000000000000003478 97.0
HFD1_k127_1027733_33 12 heme-binding sites - - - 0.000000000000000005681 95.0
HFD1_k127_1027733_34 - - - - 0.000000000000000007667 87.0
HFD1_k127_1027733_35 - - - - 0.0000000271 60.0
HFD1_k127_1027733_36 - - - - 0.0000005288 60.0
HFD1_k127_1027733_37 12 heme-binding sites - - - 0.000001858 61.0
HFD1_k127_1027733_38 tryptophanase activity K01667,K07516 - 1.1.1.35,4.1.99.1 0.00002177 48.0
HFD1_k127_1027733_39 Class III cytochrome C family - - - 0.0001118 54.0
HFD1_k127_1027733_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 535.0
HFD1_k127_1027733_40 Class III cytochrome C family - - - 0.0009976 49.0
HFD1_k127_1027733_5 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 525.0
HFD1_k127_1027733_6 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 473.0
HFD1_k127_1027733_7 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 463.0
HFD1_k127_1027733_8 PFAM Acetamidase Formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 462.0
HFD1_k127_1027733_9 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 447.0
HFD1_k127_1031432_0 aminotransferase class I and II K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 529.0
HFD1_k127_1031432_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 391.0
HFD1_k127_1031432_10 Conserved Protein - - - 0.0000000000003451 73.0
HFD1_k127_1031432_12 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000005211 57.0
HFD1_k127_1031432_13 sigma-54 factor interaction domain-containing protein K02481 - - 0.00003667 52.0
HFD1_k127_1031432_2 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 337.0
HFD1_k127_1031432_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 297.0
HFD1_k127_1031432_4 alpha/beta hydrolase fold K07214 - - 0.000000000000000000000000000000000000000000000000000000000000007434 226.0
HFD1_k127_1031432_6 Cytochrome P460 - - - 0.000000000000000000000000000000000000000103 156.0
HFD1_k127_1031432_7 DinB superfamily - - - 0.000000000000000000000000000000000000001615 151.0
HFD1_k127_1031432_8 - - - - 0.00000000000000000008395 95.0
HFD1_k127_1031432_9 Domain of unknown function (DUF4440) - - - 0.00000000000004565 78.0
HFD1_k127_1040328_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 513.0
HFD1_k127_1040328_1 Replicative DNA helicase K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 430.0
HFD1_k127_1040328_10 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000003837 69.0
HFD1_k127_1040328_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 394.0
HFD1_k127_1040328_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000127 188.0
HFD1_k127_1040328_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000001181 175.0
HFD1_k127_1040328_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000004893 171.0
HFD1_k127_1040328_6 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000003692 158.0
HFD1_k127_1040328_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000002944 120.0
HFD1_k127_1040328_8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000159 106.0
HFD1_k127_1040328_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000008653 100.0
HFD1_k127_1054542_0 PFAM Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 319.0
HFD1_k127_1054542_1 Mur ligase middle domain protein K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000002191 253.0
HFD1_k127_1054542_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000001158 99.0
HFD1_k127_1054542_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000703 83.0
HFD1_k127_1111721_0 PFAM Amino acid permease K03294 - - 2.612e-220 697.0
HFD1_k127_1111721_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 5.478e-215 706.0
HFD1_k127_1111721_10 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000274 105.0
HFD1_k127_1111721_11 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000001205 60.0
HFD1_k127_1111721_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00007122 55.0
HFD1_k127_1111721_13 COG0607 Rhodanese-related sulfurtransferase - - - 0.0002876 48.0
HFD1_k127_1111721_14 SNARE associated Golgi protein - - - 0.000601 43.0
HFD1_k127_1111721_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 539.0
HFD1_k127_1111721_3 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 527.0
HFD1_k127_1111721_4 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 378.0
HFD1_k127_1111721_5 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 369.0
HFD1_k127_1111721_6 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 359.0
HFD1_k127_1111721_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006291 257.0
HFD1_k127_1111721_8 KWG Leptospira - - - 0.0000000000000000000000000000000000000000000000000000000000000006924 233.0
HFD1_k127_1111721_9 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000001259 212.0
HFD1_k127_1169107_0 metallocarboxypeptidase activity K14054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 472.0
HFD1_k127_1169107_1 enzyme related to lactoylglutathione lyase K06996 - - 0.00001271 48.0
HFD1_k127_1170720_0 4Fe-4S dicluster domain K00184 - - 0.0 1079.0
HFD1_k127_1170720_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 6.302e-271 842.0
HFD1_k127_1170720_10 YjbR - - - 0.000000000000000000000000000000000000000000000002533 176.0
HFD1_k127_1170720_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000001876 183.0
HFD1_k127_1170720_12 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000258 151.0
HFD1_k127_1170720_13 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000001495 153.0
HFD1_k127_1170720_14 DinB family - - - 0.00000000000000000000000000000000004527 141.0
HFD1_k127_1170720_15 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000009465 135.0
HFD1_k127_1170720_16 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000002299 96.0
HFD1_k127_1170720_2 Polysulphide reductase, NrfD K00185 - - 1.328e-216 682.0
HFD1_k127_1170720_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 372.0
HFD1_k127_1170720_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 365.0
HFD1_k127_1170720_5 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 323.0
HFD1_k127_1170720_6 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 308.0
HFD1_k127_1170720_7 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000009875 250.0
HFD1_k127_1170720_8 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001166 237.0
HFD1_k127_1170720_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001533 212.0
HFD1_k127_1183027_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 608.0
HFD1_k127_1183027_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 568.0
HFD1_k127_1183027_2 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.000000000000000000000000000000000000000000000000000000000000000000000002554 252.0
HFD1_k127_1183027_3 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.000000000000000000000000000000000000000000000000000000000000000000002088 240.0
HFD1_k127_1183027_4 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000000000000000000000000000000008369 228.0
HFD1_k127_1183027_5 - - - - 0.000000000000000000000000000000000000000000000000000000000007576 222.0
HFD1_k127_1183027_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000007948 193.0
HFD1_k127_1183027_7 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000001283 151.0
HFD1_k127_1183027_8 DinB superfamily K07552 - - 0.000000000000000000000000000000000007164 142.0
HFD1_k127_1183027_9 Amidohydrolase family - - - 0.0000000000000000000000164 107.0
HFD1_k127_1186304_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 352.0
HFD1_k127_1186304_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001575 274.0
HFD1_k127_1186304_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001918 258.0
HFD1_k127_119313_0 Sulfatase K01130 - 3.1.6.1 1.645e-317 980.0
HFD1_k127_119313_1 Arylsulfatase K01130 - 3.1.6.1 5.178e-256 798.0
HFD1_k127_119313_2 Cytochrome c554 and c-prime - - - 2.424e-195 635.0
HFD1_k127_119313_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000002354 246.0
HFD1_k127_119313_4 Ndr family - - - 0.00000000000000000000000000000000000000000000000000000000002079 218.0
HFD1_k127_119313_5 Protein of unknown function (DUF4239) - - - 0.00000000000000000000000000000000000000000000000004721 188.0
HFD1_k127_119313_6 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000009123 187.0
HFD1_k127_119313_7 Transposase K07491 - - 0.0000000000000000000000000000000000000000104 158.0
HFD1_k127_119313_8 - - - - 0.00000000000000000000000000000000000000009266 157.0
HFD1_k127_119313_9 - - - - 0.00000000000000000000000000000000000003208 148.0
HFD1_k127_1207044_0 peptidase K01415,K07386 - 3.4.24.71 1.08e-264 826.0
HFD1_k127_1207044_1 guanyl-nucleotide exchange factor activity K06978,K12287,K21105 - 3.1.1.102 0.0000000000000000000000000000000007187 145.0
HFD1_k127_1216295_0 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 397.0
HFD1_k127_1216295_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 349.0
HFD1_k127_1216295_10 manganese ion transmembrane transporter activity - - - 0.00000000000000000000000000000002212 147.0
HFD1_k127_1216295_12 Methyltransferase domain - - - 0.0000000000000000000000001864 113.0
HFD1_k127_1216295_13 Prolyl oligopeptidase family - - - 0.0000000000000000007902 87.0
HFD1_k127_1216295_14 Methyltransferase domain - - - 0.000000000000000006367 99.0
HFD1_k127_1216295_15 RNA cap guanine-N2 methyltransferase - - - 0.00000000000004568 87.0
HFD1_k127_1216295_16 S-layer homology domain - - - 0.00000000000005079 87.0
HFD1_k127_1216295_17 DNA integration K14059 - - 0.00000000291 61.0
HFD1_k127_1216295_18 Methyltransferase domain - - - 0.00000002895 66.0
HFD1_k127_1216295_19 Conserved repeat domain - - - 0.000003501 61.0
HFD1_k127_1216295_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 312.0
HFD1_k127_1216295_3 pyrroloquinoline quinone binding K12287 - - 0.0000000000000000000000000000000000000000000000000000000000000001994 252.0
HFD1_k127_1216295_4 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000109 246.0
HFD1_k127_1216295_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000089 241.0
HFD1_k127_1216295_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000005791 239.0
HFD1_k127_1216295_7 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000001331 237.0
HFD1_k127_1216295_8 Esterase-like activity of phytase K03929 - - 0.000000000000000000000000000000000000000000000000000007127 218.0
HFD1_k127_1216295_9 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.00000000000000000000000000000000000000004121 166.0
HFD1_k127_1216306_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0 1611.0
HFD1_k127_1216306_1 ribosome binding - - - 5.239e-308 972.0
HFD1_k127_1216306_2 ATPase involved in DNA repair K13924 - 2.1.1.80,3.1.1.61 2.435e-300 957.0
HFD1_k127_1216306_3 - - - - 3.743e-215 682.0
HFD1_k127_1216306_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 394.0
HFD1_k127_1216306_5 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002238 255.0
HFD1_k127_1216306_6 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000007915 111.0
HFD1_k127_1216306_7 - - - - 0.000000004753 68.0
HFD1_k127_1216306_8 Protein kinase domain K12132 - 2.7.11.1 0.0000002778 52.0
HFD1_k127_1277238_0 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 358.0
HFD1_k127_1277238_1 Ornithine cyclodeaminase/mu-crystallin family K21721 - 1.5.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 342.0
HFD1_k127_1277238_10 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000001777 98.0
HFD1_k127_1277238_11 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0001038 55.0
HFD1_k127_1277238_12 heat shock protein binding - - - 0.0002395 53.0
HFD1_k127_1277238_13 heat shock protein binding - - - 0.0005464 46.0
HFD1_k127_1277238_2 Alpha-aspartyl dipeptidase-like K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000005801 282.0
HFD1_k127_1277238_3 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006869 257.0
HFD1_k127_1277238_4 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001594 250.0
HFD1_k127_1277238_5 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005507 250.0
HFD1_k127_1277238_6 cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001202 226.0
HFD1_k127_1277238_7 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000002568 224.0
HFD1_k127_1277238_8 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000005197 215.0
HFD1_k127_1277238_9 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000001609 166.0
HFD1_k127_128453_0 Glucodextranase, domain N K01178 - 3.2.1.3 1.633e-201 649.0
HFD1_k127_128453_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 361.0
HFD1_k127_128453_2 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000006369 203.0
HFD1_k127_128453_3 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000002284 203.0
HFD1_k127_128453_4 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000001096 157.0
HFD1_k127_128453_5 ATPase associated with various cellular activities, AAA_5 K02584 - - 0.00000000000000001248 83.0
HFD1_k127_128453_6 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000001395 85.0
HFD1_k127_128453_7 Diguanylate cyclase - - - 0.0000000000000004877 81.0
HFD1_k127_128453_8 glycosyl hydrolase, family 3 K05349 - 3.2.1.21 0.0000004287 53.0
HFD1_k127_1297401_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1406.0
HFD1_k127_1297401_1 Nitrite and sulphite reductase 4Fe-4S K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 425.0
HFD1_k127_1297401_11 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000002687 58.0
HFD1_k127_1297401_13 translation initiation factor activity K02004,K10939,K12257,K14393 - - 0.000002198 61.0
HFD1_k127_1297401_14 STAS domain K20978 - - 0.000002346 54.0
HFD1_k127_1297401_15 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00002112 55.0
HFD1_k127_1297401_2 Formate dehydrogenase beta subunit K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 329.0
HFD1_k127_1297401_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 326.0
HFD1_k127_1297401_4 - - - - 0.0000000000000000000000000000000000000000000000000000000001672 206.0
HFD1_k127_1297401_5 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000002239 198.0
HFD1_k127_1297401_6 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000001487 183.0
HFD1_k127_1297401_7 - - - - 0.00000000000000000000000000000000000000000000005396 173.0
HFD1_k127_1297401_8 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000001148 178.0
HFD1_k127_1297401_9 von Willebrand factor type A domain - - - 0.000000000000000000002817 98.0
HFD1_k127_129940_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 492.0
HFD1_k127_129940_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 352.0
HFD1_k127_129940_2 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 336.0
HFD1_k127_129940_3 polysaccharide deacetylase K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 286.0
HFD1_k127_129940_4 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000003616 248.0
HFD1_k127_129940_5 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000007424 211.0
HFD1_k127_129940_6 - - - - 0.00000000000000000000000004622 109.0
HFD1_k127_129940_7 Predicted membrane protein (DUF2231) - - - 0.000000000000000001046 91.0
HFD1_k127_129940_8 Protein of unknown function (DUF3309) - - - 0.00000000000000001478 83.0
HFD1_k127_1414810_0 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 398.0
HFD1_k127_1414810_1 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 391.0
HFD1_k127_1414810_2 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 356.0
HFD1_k127_1414810_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000002498 224.0
HFD1_k127_1414810_4 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000009971 165.0
HFD1_k127_1414810_5 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000007826 117.0
HFD1_k127_1432225_0 Beta propeller domain - - - 7.788e-219 699.0
HFD1_k127_1432225_1 PFAM RES domain - - - 0.0000000000000000000000000000000000002097 147.0
HFD1_k127_1432225_2 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000001593 128.0
HFD1_k127_1432225_3 PFAM HNH endonuclease - - - 0.000000000000000000000000000002366 128.0
HFD1_k127_1432225_4 Transglycosylase associated protein - - - 0.00000000000000000000005749 102.0
HFD1_k127_1432225_5 - - - - 0.000004607 55.0
HFD1_k127_1485583_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 2702.0
HFD1_k127_1485583_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 6.51e-265 832.0
HFD1_k127_1485583_10 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006739 291.0
HFD1_k127_1485583_11 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001119 274.0
HFD1_k127_1485583_12 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002354 231.0
HFD1_k127_1485583_13 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000009387 231.0
HFD1_k127_1485583_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000009556 232.0
HFD1_k127_1485583_15 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000003341 222.0
HFD1_k127_1485583_16 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000000000009794 220.0
HFD1_k127_1485583_17 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000003543 205.0
HFD1_k127_1485583_18 - - - - 0.00000000000000000000000000000000000000000000000006834 180.0
HFD1_k127_1485583_19 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000003289 177.0
HFD1_k127_1485583_2 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 581.0
HFD1_k127_1485583_20 Domain of unknown function (DUF1990) - - - 0.0000000000000000000000000000000000000001261 156.0
HFD1_k127_1485583_21 Methyltransferase domain - - - 0.0000000000000000000000000000000003906 141.0
HFD1_k127_1485583_22 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000003809 128.0
HFD1_k127_1485583_23 Protein of unknown function (DUF2752) - - - 0.0000000000000000000000000103 114.0
HFD1_k127_1485583_24 Protein of unknown function, DUF393 - - - 0.0000000000000000000000001307 109.0
HFD1_k127_1485583_25 TM2 domain - - - 0.0000000000000000000000001401 111.0
HFD1_k127_1485583_26 radical SAM domain protein - - - 0.000000000000001137 81.0
HFD1_k127_1485583_27 aminopeptidase activity - - - 0.000000000000009593 75.0
HFD1_k127_1485583_28 Interferon-induced transmembrane protein - - - 0.00000000001104 68.0
HFD1_k127_1485583_29 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000001851 75.0
HFD1_k127_1485583_3 coenzyme binding K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 452.0
HFD1_k127_1485583_30 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000001119 67.0
HFD1_k127_1485583_31 - - - - 0.000005041 59.0
HFD1_k127_1485583_4 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 472.0
HFD1_k127_1485583_5 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 433.0
HFD1_k127_1485583_6 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 408.0
HFD1_k127_1485583_7 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 392.0
HFD1_k127_1485583_8 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 347.0
HFD1_k127_1485583_9 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 338.0
HFD1_k127_1486685_0 C-terminus of AA_permease K03294 - - 1.478e-211 674.0
HFD1_k127_1486685_1 Beta-lactamase - - - 5.073e-195 625.0
HFD1_k127_1486685_10 L,D-transpeptidase catalytic domain - - - 0.000000005512 68.0
HFD1_k127_1486685_11 von Willebrand factor (vWF) type A domain K07114 - - 0.00002599 56.0
HFD1_k127_1486685_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 601.0
HFD1_k127_1486685_3 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 355.0
HFD1_k127_1486685_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 310.0
HFD1_k127_1486685_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 307.0
HFD1_k127_1486685_6 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002228 277.0
HFD1_k127_1486685_7 Putative restriction endonuclease - - - 0.000000000000000000000000000000003044 132.0
HFD1_k127_1486685_8 Protein of unknown function (DUF1232) - - - 0.0000000000000000000006281 102.0
HFD1_k127_1486685_9 L,D-transpeptidase catalytic domain - - - 0.0000000000000000008065 87.0
HFD1_k127_1494759_0 Zinc metalloprotease (Elastase) - - - 2.063e-266 839.0
HFD1_k127_1494759_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.643e-253 797.0
HFD1_k127_1494759_10 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 407.0
HFD1_k127_1494759_11 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 389.0
HFD1_k127_1494759_12 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 349.0
HFD1_k127_1494759_13 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 346.0
HFD1_k127_1494759_14 Protein of unknown function (DUF4256) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 330.0
HFD1_k127_1494759_15 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 328.0
HFD1_k127_1494759_17 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
HFD1_k127_1494759_18 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 302.0
HFD1_k127_1494759_19 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003341 284.0
HFD1_k127_1494759_2 von Willebrand factor, type A K07114 - - 4.841e-209 677.0
HFD1_k127_1494759_20 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000121 277.0
HFD1_k127_1494759_21 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000646 273.0
HFD1_k127_1494759_22 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001777 275.0
HFD1_k127_1494759_23 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000725 260.0
HFD1_k127_1494759_24 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009157 252.0
HFD1_k127_1494759_25 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000378 251.0
HFD1_k127_1494759_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002706 240.0
HFD1_k127_1494759_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000001426 222.0
HFD1_k127_1494759_28 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000006692 212.0
HFD1_k127_1494759_29 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000002761 196.0
HFD1_k127_1494759_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 612.0
HFD1_k127_1494759_30 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000001681 186.0
HFD1_k127_1494759_31 DinB family - - - 0.00000000000000000000000000000000000000000000000001952 187.0
HFD1_k127_1494759_32 DoxX - - - 0.00000000000000000000000000000000000000000000000003521 188.0
HFD1_k127_1494759_33 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000002848 199.0
HFD1_k127_1494759_34 Protein of unknown function (DUF3465) - - - 0.00000000000000000000000000000000000000000000004137 173.0
HFD1_k127_1494759_35 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.0000000000000000000000000000000000000000000002392 171.0
HFD1_k127_1494759_36 Forkhead associated domain - - - 0.000000000000000000000000000000000000000001123 175.0
HFD1_k127_1494759_37 protein and some similarities with VgrG protein - - - 0.00000000000000000000000000000000000000001054 156.0
HFD1_k127_1494759_38 - - - - 0.0000000000000000000000000000000000002818 143.0
HFD1_k127_1494759_39 NIPSNAP - - - 0.000000000000000000000000000000000001886 141.0
HFD1_k127_1494759_40 - - - - 0.000000000000000000000000000000009968 129.0
HFD1_k127_1494759_41 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000000000000000000000009099 142.0
HFD1_k127_1494759_43 Ferredoxin - - - 0.00000000000000000000000005641 113.0
HFD1_k127_1494759_44 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000003226 119.0
HFD1_k127_1494759_45 - - - - 0.0000000000000000000001604 103.0
HFD1_k127_1494759_46 DinB family - - - 0.00000000000000000007021 96.0
HFD1_k127_1494759_47 Domain of unknown function (DUF4437) - - - 0.000000000000000000301 96.0
HFD1_k127_1494759_48 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K15342 - 2.7.7.49 0.000000000000001015 78.0
HFD1_k127_1494759_49 Pilus assembly protein PilX K02673 - - 0.00000000000002633 86.0
HFD1_k127_1494759_5 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 508.0
HFD1_k127_1494759_50 twitching motility protein K02669 - - 0.00000000001016 68.0
HFD1_k127_1494759_51 serine threonine protein kinase - - - 0.0000000001139 75.0
HFD1_k127_1494759_52 tRNA wobble cytosine modification - - - 0.0000000003303 64.0
HFD1_k127_1494759_53 - - - - 0.000000003032 63.0
HFD1_k127_1494759_54 - - - - 0.00000001284 57.0
HFD1_k127_1494759_56 - - - - 0.00002593 48.0
HFD1_k127_1494759_57 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00007186 53.0
HFD1_k127_1494759_6 Transporter-associated region K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 499.0
HFD1_k127_1494759_7 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 512.0
HFD1_k127_1494759_8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 479.0
HFD1_k127_1494759_9 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 424.0
HFD1_k127_1545140_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 9.645e-309 961.0
HFD1_k127_1545140_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 7.603e-204 658.0
HFD1_k127_1545140_10 - - - - 0.000000000000000000000000000000000000000000000000971 186.0
HFD1_k127_1545140_11 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000006829 175.0
HFD1_k127_1545140_12 ORF6N domain - - - 0.00000000000000000000000000000000000000000000002256 177.0
HFD1_k127_1545140_13 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000003123 181.0
HFD1_k127_1545140_14 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000002161 164.0
HFD1_k127_1545140_15 Calcineurin-like phosphoesterase superfamily domain K07313 - 3.1.3.16 0.000000000000000000000000000000000000066 150.0
HFD1_k127_1545140_16 - - - - 0.00000000000000000000000002175 115.0
HFD1_k127_1545140_17 Tyrosine phosphatase family - - - 0.0000000000000000002781 98.0
HFD1_k127_1545140_19 Ricin-type beta-trefoil - - - 0.0000000000002668 79.0
HFD1_k127_1545140_2 transmembrane transporter activity K08196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 605.0
HFD1_k127_1545140_20 Methionine biosynthesis protein MetW - - - 0.000000000003495 77.0
HFD1_k127_1545140_21 Domain of unknown function (DUF4956) - - - 0.00000000008893 73.0
HFD1_k127_1545140_22 Carboxypeptidase regulatory-like domain - - - 0.0001471 52.0
HFD1_k127_1545140_3 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 354.0
HFD1_k127_1545140_4 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003776 260.0
HFD1_k127_1545140_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000003124 210.0
HFD1_k127_1545140_6 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000001046 207.0
HFD1_k127_1545140_7 Membrane - - - 0.0000000000000000000000000000000000000000000000000000007386 215.0
HFD1_k127_1545140_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000009051 187.0
HFD1_k127_1545140_9 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000003673 195.0
HFD1_k127_1553705_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 316.0
HFD1_k127_1553705_1 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000001755 216.0
HFD1_k127_1553705_2 Haem-degrading - - - 0.0000000000002072 77.0
HFD1_k127_1553705_3 lactoylglutathione lyase activity K11210 - - 0.0000000002323 71.0
HFD1_k127_157304_0 Transporter, small conductance mechanosensitive ion channel MscS family protein K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000284 249.0
HFD1_k127_157304_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000006491 140.0
HFD1_k127_157304_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00001289 56.0
HFD1_k127_157483_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 4.266e-316 988.0
HFD1_k127_157483_1 CoA enzyme activase uncharacterised domain (DUF2229) - - - 5.634e-246 811.0
HFD1_k127_157483_10 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000001193 222.0
HFD1_k127_157483_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000002702 218.0
HFD1_k127_157483_12 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000585 204.0
HFD1_k127_157483_13 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000006999 209.0
HFD1_k127_157483_14 Protein of unknown function (DUF4199) - - - 0.00000000000000000000000000000000000000000000002349 177.0
HFD1_k127_157483_15 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000005277 134.0
HFD1_k127_157483_16 Universal stress protein family - - - 0.00000000000000000000000000000000307 133.0
HFD1_k127_157483_17 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000005264 97.0
HFD1_k127_157483_18 PFAM response regulator receiver K02483 - - 0.000000000000000007306 91.0
HFD1_k127_157483_19 - - - - 0.00000000000001689 74.0
HFD1_k127_157483_2 Sigma-70 region 2 K03088 - - 2.829e-224 701.0
HFD1_k127_157483_20 - - - - 0.0000000000002091 73.0
HFD1_k127_157483_21 Belongs to the universal stress protein A family - - - 0.000000000006953 76.0
HFD1_k127_157483_23 PFAM Alcohol dehydrogenase K13979 - - 0.0004131 46.0
HFD1_k127_157483_3 Alcohol dehydrogenase GroES-like domain K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 585.0
HFD1_k127_157483_4 Domain of unknown function (DUF4070) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 504.0
HFD1_k127_157483_5 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 469.0
HFD1_k127_157483_6 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 311.0
HFD1_k127_157483_7 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003765 254.0
HFD1_k127_157483_8 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002904 249.0
HFD1_k127_157483_9 Pfam RibD C-terminal domain K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000008774 239.0
HFD1_k127_1623115_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 428.0
HFD1_k127_1623115_1 - - - - 0.000000000000001137 81.0
HFD1_k127_1623115_2 YcxB-like protein - - - 0.0000000003805 67.0
HFD1_k127_1623115_3 Belongs to the 'phage' integrase family - - - 0.0007044 46.0
HFD1_k127_1644416_0 rRNA (guanine-N2-)-methyltransferase activity K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.304,2.1.1.333 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 593.0
HFD1_k127_1644416_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 378.0
HFD1_k127_1644416_2 TIR domain - - - 0.00000000000000000000000000000000000000000000003542 181.0
HFD1_k127_1644416_4 SnoaL-like domain - - - 0.0000000000000000000000000003558 116.0
HFD1_k127_1644416_5 - - - - 0.0000005513 51.0
HFD1_k127_1645305_0 cellulose binding K13735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 425.0
HFD1_k127_1645305_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00004022 58.0
HFD1_k127_1661807_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 596.0
HFD1_k127_1661807_1 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 582.0
HFD1_k127_1661807_10 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000001013 187.0
HFD1_k127_1661807_11 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000002 150.0
HFD1_k127_1661807_12 PFAM aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000005885 151.0
HFD1_k127_1661807_13 von Willebrand factor, type A - - - 0.0000000000000000000000000000003408 136.0
HFD1_k127_1661807_14 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000502 128.0
HFD1_k127_1661807_15 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000004391 111.0
HFD1_k127_1661807_16 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000006841 110.0
HFD1_k127_1661807_17 B-1 B cell differentiation K07126 - - 0.000000000000000006567 94.0
HFD1_k127_1661807_18 gag-polyprotein putative aspartyl protease - - - 0.0002219 53.0
HFD1_k127_1661807_19 - - - - 0.0003 49.0
HFD1_k127_1661807_2 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 391.0
HFD1_k127_1661807_3 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 378.0
HFD1_k127_1661807_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 361.0
HFD1_k127_1661807_5 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 318.0
HFD1_k127_1661807_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 295.0
HFD1_k127_1661807_7 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002046 222.0
HFD1_k127_1661807_8 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000007108 232.0
HFD1_k127_1661807_9 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000001682 226.0
HFD1_k127_1682537_0 Protein of unknown function (DUF3604) - - - 1.859e-265 824.0
HFD1_k127_1682537_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 576.0
HFD1_k127_1682537_2 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 306.0
HFD1_k127_1682537_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000006212 247.0
HFD1_k127_1682537_4 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001182 241.0
HFD1_k127_1682537_5 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000000000000000001276 188.0
HFD1_k127_1682537_6 Periplasmic or secreted lipoprotein - - - 0.000000000000003918 84.0
HFD1_k127_1704547_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001252 309.0
HFD1_k127_1708214_0 Carboxypeptidase regulatory-like domain - - - 4.8e-275 883.0
HFD1_k127_1708214_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 371.0
HFD1_k127_1708214_2 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000172 289.0
HFD1_k127_1708214_3 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000005651 166.0
HFD1_k127_1708214_4 acyl-CoA dehydrogenase K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.0001032 45.0
HFD1_k127_1708985_0 Heavy metal translocating P-type atpase - - - 5.53e-237 749.0
HFD1_k127_1708985_1 glutamate--cysteine ligase - - - 1.386e-233 739.0
HFD1_k127_1708985_11 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000006737 104.0
HFD1_k127_1708985_12 Amidohydrolase family - - - 0.0000000000000000005586 92.0
HFD1_k127_1708985_13 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000006868 93.0
HFD1_k127_1708985_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 3.359e-224 702.0
HFD1_k127_1708985_3 PFAM acyl-CoA dehydrogenase domain protein - - - 8.052e-203 643.0
HFD1_k127_1708985_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 1.093e-194 618.0
HFD1_k127_1708985_5 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 460.0
HFD1_k127_1708985_6 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 453.0
HFD1_k127_1708985_7 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 383.0
HFD1_k127_1708985_8 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 295.0
HFD1_k127_1712125_0 Molybdopterin oxidoreductase Fe4S4 domain K00370 - 1.7.5.1 0.0 1778.0
HFD1_k127_1712125_1 4Fe-4S dicluster domain K00184 - - 3.096e-277 884.0
HFD1_k127_1712125_10 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 268.0
HFD1_k127_1712125_11 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002439 263.0
HFD1_k127_1712125_12 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 256.0
HFD1_k127_1712125_13 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000006985 230.0
HFD1_k127_1712125_14 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000004927 212.0
HFD1_k127_1712125_15 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000002487 207.0
HFD1_k127_1712125_16 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000001599 191.0
HFD1_k127_1712125_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001249 189.0
HFD1_k127_1712125_18 Cytochrome c - - - 0.000000000000000000000000000000000000000003658 167.0
HFD1_k127_1712125_19 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000127 159.0
HFD1_k127_1712125_2 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 4.153e-233 730.0
HFD1_k127_1712125_20 Cytochrome c - - - 0.0000000000000000000000000000000000000001354 156.0
HFD1_k127_1712125_21 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000000001351 124.0
HFD1_k127_1712125_22 PFAM DinB family protein - - - 0.00000000000000000000000000002918 124.0
HFD1_k127_1712125_23 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000004215 117.0
HFD1_k127_1712125_24 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000003228 108.0
HFD1_k127_1712125_25 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000007874 109.0
HFD1_k127_1712125_26 protein histidine kinase activity K06375 - - 0.0000000000000000000001205 106.0
HFD1_k127_1712125_27 Transcriptional regulator - - - 0.000000000000000000007853 98.0
HFD1_k127_1712125_28 Domain of unknown function (DUF4440) - - - 0.0000000000000000137 82.0
HFD1_k127_1712125_29 Domain of unknown function (DUF4440) - - - 0.000000000000000496 78.0
HFD1_k127_1712125_3 PFAM Polysulphide reductase, NrfD - - - 1.474e-210 665.0
HFD1_k127_1712125_30 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000003626 76.0
HFD1_k127_1712125_31 Cytochrome c - - - 0.00000000000008317 76.0
HFD1_k127_1712125_32 PFAM Tetratricopeptide repeat - - - 0.000000000008001 77.0
HFD1_k127_1712125_33 - - - - 0.0000001347 64.0
HFD1_k127_1712125_34 Calcineurin-like phosphoesterase - - - 0.0000003439 52.0
HFD1_k127_1712125_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 581.0
HFD1_k127_1712125_5 PFAM SMP-30 Gluconolaconase LRE domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 434.0
HFD1_k127_1712125_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 419.0
HFD1_k127_1712125_7 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 407.0
HFD1_k127_1712125_8 FAD binding domain K05712 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 390.0
HFD1_k127_1712125_9 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 337.0
HFD1_k127_1726314_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0 1077.0
HFD1_k127_1726314_1 cellulose binding - - - 3.955e-307 977.0
HFD1_k127_1726314_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000003173 165.0
HFD1_k127_1726314_11 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000001552 168.0
HFD1_k127_1726314_12 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000004387 145.0
HFD1_k127_1726314_13 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000005404 145.0
HFD1_k127_1726314_14 Domain of unknown function (DUF4252) - - - 0.0000000000000000000000000000000002674 138.0
HFD1_k127_1726314_15 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000128 105.0
HFD1_k127_1726314_16 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000002298 99.0
HFD1_k127_1726314_17 Putative addiction module component - - - 0.00000008262 57.0
HFD1_k127_1726314_18 pfam rdd - - - 0.000005823 58.0
HFD1_k127_1726314_19 von Willebrand factor, type A K07114 - - 0.0002007 53.0
HFD1_k127_1726314_2 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 586.0
HFD1_k127_1726314_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 499.0
HFD1_k127_1726314_4 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 301.0
HFD1_k127_1726314_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 294.0
HFD1_k127_1726314_6 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000004607 220.0
HFD1_k127_1726314_7 - - - - 0.0000000000000000000000000000000000000000000000000000000002409 216.0
HFD1_k127_1726314_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000001129 184.0
HFD1_k127_1726314_9 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000196 175.0
HFD1_k127_1766471_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 530.0
HFD1_k127_1766471_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 289.0
HFD1_k127_1766471_2 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000001925 134.0
HFD1_k127_1766471_3 Protein of unknown function (DUF2834) - - - 0.00000000000000000000009232 101.0
HFD1_k127_1766471_4 Beta-lactamase - - - 0.0007066 46.0
HFD1_k127_1796060_0 Peptidase family M13 K07386 - - 7.822e-215 686.0
HFD1_k127_1796060_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 538.0
HFD1_k127_1796060_10 Protein of unknown function (DUF1326) - - - 0.0000000000000000000519 98.0
HFD1_k127_1796060_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 490.0
HFD1_k127_1796060_3 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000022 286.0
HFD1_k127_1796060_4 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001734 272.0
HFD1_k127_1796060_5 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000007177 191.0
HFD1_k127_1796060_6 2Fe-2S -binding K13483 - - 0.0000000000000000000000000000000000000000000000000001102 194.0
HFD1_k127_1796060_7 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000002286 188.0
HFD1_k127_1796060_8 Cupin domain - - - 0.00000000000000000000000000000000001357 142.0
HFD1_k127_1796060_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000001459 106.0
HFD1_k127_181866_0 Dienelactone hydrolase family - - - 2.144e-262 824.0
HFD1_k127_181866_1 cellulose binding - - - 6.395e-260 834.0
HFD1_k127_181866_10 Small integral membrane protein - - - 0.00000000000000000000000000000000001881 138.0
HFD1_k127_181866_11 - - - - 0.000000000000000000001445 99.0
HFD1_k127_181866_12 Domain of unknown function (DU1801) - - - 0.0000000000000008089 83.0
HFD1_k127_181866_13 Hydrolase CocE NonD family K06978 - - 0.00000000000001421 74.0
HFD1_k127_181866_2 DNA polymerase beta thumb K02347 - - 1.002e-194 623.0
HFD1_k127_181866_3 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 382.0
HFD1_k127_181866_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 376.0
HFD1_k127_181866_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004011 280.0
HFD1_k127_181866_6 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000009205 223.0
HFD1_k127_181866_7 Belongs to the peptidase S41A family K03797,K08676 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000001094 217.0
HFD1_k127_181866_8 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000003904 212.0
HFD1_k127_181866_9 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000001262 201.0
HFD1_k127_1834356_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 7.874e-242 753.0
HFD1_k127_1834356_1 - - - - 0.000000000001657 79.0
HFD1_k127_1841549_0 Carboxypeptidase regulatory-like domain - - - 1.093e-196 650.0
HFD1_k127_1841549_1 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 311.0
HFD1_k127_1841549_2 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005198 264.0
HFD1_k127_1841549_3 COGs COG3316 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000002753 233.0
HFD1_k127_1841549_4 COGs COG3316 Transposase and inactivated derivatives - - - 0.00000000000000000000000002146 109.0
HFD1_k127_1841549_5 TIGRFAM Phage - - - 0.00000000000006029 77.0
HFD1_k127_1841549_6 Anaphase-promoting complex, cyclosome, subunit 3 K03350 - - 0.00000003965 65.0
HFD1_k127_1841549_9 B12 binding domain K01849 - 5.4.99.2 0.0001496 44.0
HFD1_k127_1855664_0 Belongs to the ClpA ClpB family K03696 - - 1.371e-256 813.0
HFD1_k127_1855664_1 Protein tyrosine kinase - - - 4.138e-229 739.0
HFD1_k127_1855664_10 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 587.0
HFD1_k127_1855664_11 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 559.0
HFD1_k127_1855664_12 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 570.0
HFD1_k127_1855664_13 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 550.0
HFD1_k127_1855664_14 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 543.0
HFD1_k127_1855664_15 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 544.0
HFD1_k127_1855664_16 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 540.0
HFD1_k127_1855664_17 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 526.0
HFD1_k127_1855664_18 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 496.0
HFD1_k127_1855664_19 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 438.0
HFD1_k127_1855664_2 TonB dependent receptor K16090 - - 1.935e-217 700.0
HFD1_k127_1855664_20 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 461.0
HFD1_k127_1855664_21 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 413.0
HFD1_k127_1855664_22 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 376.0
HFD1_k127_1855664_23 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 362.0
HFD1_k127_1855664_24 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 351.0
HFD1_k127_1855664_25 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 358.0
HFD1_k127_1855664_26 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 325.0
HFD1_k127_1855664_27 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 317.0
HFD1_k127_1855664_28 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009276 305.0
HFD1_k127_1855664_29 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 312.0
HFD1_k127_1855664_3 radical SAM domain protein - - - 2.764e-215 679.0
HFD1_k127_1855664_30 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009502 280.0
HFD1_k127_1855664_31 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 268.0
HFD1_k127_1855664_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002164 256.0
HFD1_k127_1855664_33 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000294 250.0
HFD1_k127_1855664_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002339 251.0
HFD1_k127_1855664_35 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000004986 228.0
HFD1_k127_1855664_36 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000001111 211.0
HFD1_k127_1855664_37 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000008827 169.0
HFD1_k127_1855664_38 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000001073 166.0
HFD1_k127_1855664_39 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000002179 159.0
HFD1_k127_1855664_4 PFAM FAD dependent oxidoreductase - - - 5.922e-211 666.0
HFD1_k127_1855664_40 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000001977 147.0
HFD1_k127_1855664_41 - K16923 - - 0.000000000000000000000000000000004807 143.0
HFD1_k127_1855664_42 Rieske-like [2Fe-2S] domain K05710,K14578 - - 0.0000000000000000000000000000004061 125.0
HFD1_k127_1855664_43 - - - - 0.000000000000000000000003111 114.0
HFD1_k127_1855664_44 Transglutaminase-like superfamily - - - 0.00000000000000000003811 98.0
HFD1_k127_1855664_45 nuclear chromosome segregation - - - 0.0000000000000000002775 102.0
HFD1_k127_1855664_46 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.000000000000000001077 95.0
HFD1_k127_1855664_47 peptidase M15B and M15C DD-carboxypeptidase VanY - - - 0.00000000000000001837 92.0
HFD1_k127_1855664_48 Reprolysin (M12B) family zinc metalloprotease - - - 0.000000000000000878 92.0
HFD1_k127_1855664_49 Tetratricopeptide repeat - - - 0.000000000001543 81.0
HFD1_k127_1855664_5 Involved in the tonB-independent uptake of proteins - - - 1.503e-206 674.0
HFD1_k127_1855664_50 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000006645 76.0
HFD1_k127_1855664_51 - - - - 0.000000003203 65.0
HFD1_k127_1855664_52 Outer membrane protein (OmpH-like) K06142 - - 0.000000003924 65.0
HFD1_k127_1855664_53 Outer membrane protein (OmpH-like) K06142 - - 0.00000001373 64.0
HFD1_k127_1855664_54 Protein kinase domain K12132 - 2.7.11.1 0.0000006942 58.0
HFD1_k127_1855664_55 Adenylate cyclase - - - 0.000001351 52.0
HFD1_k127_1855664_56 Transcriptional regulatory protein, C terminal - - - 0.000001792 50.0
HFD1_k127_1855664_57 Domain of unknown function (DUF4388) - - - 0.0000257 55.0
HFD1_k127_1855664_58 - - - - 0.0002417 50.0
HFD1_k127_1855664_59 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0005555 44.0
HFD1_k127_1855664_6 Protein kinase domain K12132 - 2.7.11.1 5.063e-201 656.0
HFD1_k127_1855664_7 Peptidase family M49 - - - 5.427e-201 640.0
HFD1_k127_1855664_8 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 608.0
HFD1_k127_1855664_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 605.0
HFD1_k127_1884016_0 Tail sheath protein K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 312.0
HFD1_k127_1884016_1 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000007598 240.0
HFD1_k127_1884016_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001548 202.0
HFD1_k127_1884016_3 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000001094 148.0
HFD1_k127_1884016_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000007858 108.0
HFD1_k127_1884016_5 Domain of unknown function (DUF4440) - - - 0.000000000001824 73.0
HFD1_k127_1913421_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1565.0
HFD1_k127_1913421_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1225.0
HFD1_k127_1913421_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 396.0
HFD1_k127_1913421_11 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 378.0
HFD1_k127_1913421_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 341.0
HFD1_k127_1913421_13 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 340.0
HFD1_k127_1913421_14 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 331.0
HFD1_k127_1913421_15 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 330.0
HFD1_k127_1913421_16 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 301.0
HFD1_k127_1913421_17 Pfam Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001144 273.0
HFD1_k127_1913421_18 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000002288 256.0
HFD1_k127_1913421_19 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000127 252.0
HFD1_k127_1913421_2 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1073.0
HFD1_k127_1913421_20 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001942 252.0
HFD1_k127_1913421_21 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002327 234.0
HFD1_k127_1913421_22 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001297 235.0
HFD1_k127_1913421_23 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000003255 218.0
HFD1_k127_1913421_24 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000006127 202.0
HFD1_k127_1913421_25 DoxX - - - 0.000000000000000000000000000000000000000000000000000001619 196.0
HFD1_k127_1913421_26 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000007964 203.0
HFD1_k127_1913421_27 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000001199 141.0
HFD1_k127_1913421_3 PFAM Glycoside hydrolase, family 2, TIM barrel K01190 - 3.2.1.23 0.0 1020.0
HFD1_k127_1913421_4 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 5.543e-295 926.0
HFD1_k127_1913421_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 506.0
HFD1_k127_1913421_6 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 447.0
HFD1_k127_1913421_7 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 421.0
HFD1_k127_1913421_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 422.0
HFD1_k127_1913421_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 404.0
HFD1_k127_1965231_0 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 533.0
HFD1_k127_1965231_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004998 279.0
HFD1_k127_1965231_2 - - - - 0.000000000000000000000009413 104.0
HFD1_k127_2025449_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 389.0
HFD1_k127_2085020_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 482.0
HFD1_k127_2085020_1 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000001791 183.0
HFD1_k127_2085020_2 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000004303 184.0
HFD1_k127_2085020_3 denitrification pathway - - - 0.0000114 52.0
HFD1_k127_2178146_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1412.0
HFD1_k127_2178146_1 Male sterility protein K01897 - 6.2.1.3 0.0 1272.0
HFD1_k127_2178146_10 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004616 252.0
HFD1_k127_2178146_11 PFAM acid phosphatase (Class B) - - - 0.0000000000000000000000000000000000000000000000000000000000000002224 230.0
HFD1_k127_2178146_12 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000002493 224.0
HFD1_k127_2178146_13 - - - - 0.0000000000000000000000000000000000000000000006492 169.0
HFD1_k127_2178146_14 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000829 177.0
HFD1_k127_2178146_15 - - - - 0.0000000000000000000000000000000000001154 146.0
HFD1_k127_2178146_16 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000000000000000000001069 144.0
HFD1_k127_2178146_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000004435 136.0
HFD1_k127_2178146_18 Ankyrin repeats (3 copies) - - - 0.00000000000001188 81.0
HFD1_k127_2178146_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 2.438e-302 947.0
HFD1_k127_2178146_3 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 6.339e-289 916.0
HFD1_k127_2178146_4 Domain of unknown function (DUF2088) - - - 1.692e-224 706.0
HFD1_k127_2178146_5 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 435.0
HFD1_k127_2178146_6 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 344.0
HFD1_k127_2178146_7 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 300.0
HFD1_k127_2178146_8 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 290.0
HFD1_k127_2178146_9 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001488 258.0
HFD1_k127_2196345_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 477.0
HFD1_k127_2196345_1 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 357.0
HFD1_k127_2196345_2 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000149 218.0
HFD1_k127_2196345_3 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000005204 207.0
HFD1_k127_2196345_4 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000008488 182.0
HFD1_k127_2196345_5 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000003262 177.0
HFD1_k127_2196345_6 RNA recognition motif - - - 0.000000000000000000000000002475 118.0
HFD1_k127_2196345_7 SnoaL-like polyketide cyclase - - - 0.00000000000000000008882 92.0
HFD1_k127_2287382_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000009841 207.0
HFD1_k127_2287382_1 Cysteine-rich motif following a subset of SET domains K07117 - - 0.00000000000000000000000000000000000000000000000000000002664 201.0
HFD1_k127_2312940_0 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 450.0
HFD1_k127_2312940_1 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 464.0
HFD1_k127_2312940_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 413.0
HFD1_k127_2312940_3 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 412.0
HFD1_k127_2312940_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009084 275.0
HFD1_k127_2312940_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002717 261.0
HFD1_k127_2312940_6 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000004317 256.0
HFD1_k127_2312940_7 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000002018 185.0
HFD1_k127_2312940_8 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000001981 167.0
HFD1_k127_2380305_0 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 519.0
HFD1_k127_2380305_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 489.0
HFD1_k127_2380305_10 23S rRNA-intervening sequence protein - - - 0.0008138 45.0
HFD1_k127_2380305_2 Acts as a magnesium transporter K06213 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 437.0
HFD1_k127_2380305_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 329.0
HFD1_k127_2380305_4 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 304.0
HFD1_k127_2380305_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000178 290.0
HFD1_k127_2380305_6 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000001343 250.0
HFD1_k127_2380305_7 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000000000000002177 159.0
HFD1_k127_2380305_8 Amino acid permease - - - 0.00000000000000000000000000001132 120.0
HFD1_k127_2380305_9 S23 ribosomal protein - - - 0.000002544 52.0
HFD1_k127_2382716_0 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 294.0
HFD1_k127_2382716_1 - - - - 0.00000000000000000000000000000000000000000000000000000468 197.0
HFD1_k127_2382716_2 - - - - 0.0000000000000000000000000000001413 125.0
HFD1_k127_2382716_3 C4-type zinc ribbon domain K07164 - - 0.0000000000000000003881 96.0
HFD1_k127_2383854_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 6.374e-225 704.0
HFD1_k127_2383854_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 580.0
HFD1_k127_2383854_10 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001204 251.0
HFD1_k127_2383854_11 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006572 226.0
HFD1_k127_2383854_12 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000149 209.0
HFD1_k127_2383854_13 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000001152 203.0
HFD1_k127_2383854_14 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000001304 189.0
HFD1_k127_2383854_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000008673 172.0
HFD1_k127_2383854_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000002222 153.0
HFD1_k127_2383854_17 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000001018 142.0
HFD1_k127_2383854_18 CBS domain - - - 0.000000000000000000007437 98.0
HFD1_k127_2383854_19 Thiamine-binding protein - - - 0.000000000000000008087 87.0
HFD1_k127_2383854_2 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 565.0
HFD1_k127_2383854_20 PHP domain K02347 - - 0.0000000000008206 70.0
HFD1_k127_2383854_21 Domain of unknown function (DUF374) K09778 - - 0.0000000002057 71.0
HFD1_k127_2383854_22 synthetase K01895 - 6.2.1.1 0.000000618 51.0
HFD1_k127_2383854_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 488.0
HFD1_k127_2383854_4 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 395.0
HFD1_k127_2383854_5 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 384.0
HFD1_k127_2383854_6 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 360.0
HFD1_k127_2383854_7 PFAM Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 311.0
HFD1_k127_2383854_8 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001789 281.0
HFD1_k127_2383854_9 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 254.0
HFD1_k127_240236_0 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 277.0
HFD1_k127_240236_1 Beta-lactamase - - - 0.000000000000000000000000000000000004057 152.0
HFD1_k127_240236_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000001061 59.0
HFD1_k127_2435081_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 503.0
HFD1_k127_2435081_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 393.0
HFD1_k127_2435081_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000001763 179.0
HFD1_k127_2435081_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000002294 175.0
HFD1_k127_2435081_12 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000488 164.0
HFD1_k127_2435081_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000004336 157.0
HFD1_k127_2435081_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000003758 151.0
HFD1_k127_2435081_15 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000002703 132.0
HFD1_k127_2435081_16 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002058 115.0
HFD1_k127_2435081_17 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000001094 110.0
HFD1_k127_2435081_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000002348 102.0
HFD1_k127_2435081_19 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000005338 98.0
HFD1_k127_2435081_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 309.0
HFD1_k127_2435081_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000008567 94.0
HFD1_k127_2435081_21 Ribosomal protein L30 K02907 - - 0.00000000000001318 75.0
HFD1_k127_2435081_22 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 0.000003911 50.0
HFD1_k127_2435081_23 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000893 47.0
HFD1_k127_2435081_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000294 273.0
HFD1_k127_2435081_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000001394 239.0
HFD1_k127_2435081_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000001067 223.0
HFD1_k127_2435081_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000002345 221.0
HFD1_k127_2435081_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000005329 209.0
HFD1_k127_2435081_8 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000008107 212.0
HFD1_k127_2435081_9 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000004394 187.0
HFD1_k127_2442609_0 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 497.0
HFD1_k127_2442609_1 cell redox homeostasis K03671 - - 0.00000000006944 66.0
HFD1_k127_2457823_0 Multicopper oxidase - - - 0.0 1050.0
HFD1_k127_2457823_1 Hydrolase CocE NonD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 539.0
HFD1_k127_2457823_2 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 348.0
HFD1_k127_2457823_3 COG0464 ATPases of the AAA class - - - 0.000000000000000000000000000000000001839 142.0
HFD1_k127_246371_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 624.0
HFD1_k127_246371_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 541.0
HFD1_k127_246371_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 358.0
HFD1_k127_2479923_0 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 2.581e-240 751.0
HFD1_k127_2479923_1 DNA-binding transcription factor activity K02081,K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002887 269.0
HFD1_k127_2479923_2 Melibiase K07407 GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0009056,GO:0015925,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0042802,GO:0042803,GO:0046983,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000001195 243.0
HFD1_k127_2479923_3 Alpha galactosidase A K07407 - 3.2.1.22 0.0000000000006735 83.0
HFD1_k127_2479923_4 lytic transglycosylase activity K03194 - - 0.000000000007569 77.0
HFD1_k127_2483428_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1267.0
HFD1_k127_2483428_1 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 - 1.3.5.1,1.3.5.4 1.412e-274 856.0
HFD1_k127_2483428_10 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 609.0
HFD1_k127_2483428_101 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.000000000000001089 85.0
HFD1_k127_2483428_102 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000002444 79.0
HFD1_k127_2483428_103 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.0000000000001829 83.0
HFD1_k127_2483428_104 - - - - 0.0000000000004745 80.0
HFD1_k127_2483428_105 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.000000000001169 72.0
HFD1_k127_2483428_106 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000715 76.0
HFD1_k127_2483428_107 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000001411 68.0
HFD1_k127_2483428_108 gag-polyprotein putative aspartyl protease - - - 0.00000000003425 76.0
HFD1_k127_2483428_109 Tetratricopeptide repeat - - - 0.00000000004303 75.0
HFD1_k127_2483428_11 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 545.0
HFD1_k127_2483428_110 Cytochrome C oxidase, cbb3-type, subunit III K12263 - - 0.0000000028 63.0
HFD1_k127_2483428_111 Belongs to the glycosyl hydrolase 18 family K01179,K01183 - 3.2.1.14,3.2.1.4 0.000000005447 71.0
HFD1_k127_2483428_112 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000001592 69.0
HFD1_k127_2483428_113 PFAM IstB domain protein ATP-binding protein - - - 0.0000001426 52.0
HFD1_k127_2483428_114 SMART Transport-associated and nodulation region K04065 - - 0.000001245 57.0
HFD1_k127_2483428_115 TonB-dependent receptor - - - 0.0000315 50.0
HFD1_k127_2483428_116 PFAM S23 ribosomal protein - - - 0.0001187 48.0
HFD1_k127_2483428_118 Tetratricopeptide repeat K02656 - - 0.0002904 53.0
HFD1_k127_2483428_119 Tetratricopeptide repeat - - - 0.0003558 53.0
HFD1_k127_2483428_12 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 546.0
HFD1_k127_2483428_120 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0005426 49.0
HFD1_k127_2483428_121 Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation - GO:0005575,GO:0016020 - 0.0007178 51.0
HFD1_k127_2483428_122 COG0457 FOG TPR repeat - - - 0.0008269 51.0
HFD1_k127_2483428_13 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 561.0
HFD1_k127_2483428_14 AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 547.0
HFD1_k127_2483428_15 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 523.0
HFD1_k127_2483428_16 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 496.0
HFD1_k127_2483428_17 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 482.0
HFD1_k127_2483428_18 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 470.0
HFD1_k127_2483428_19 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 461.0
HFD1_k127_2483428_2 Heat shock 70 kDa protein K04043 - - 1.164e-228 722.0
HFD1_k127_2483428_20 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 448.0
HFD1_k127_2483428_21 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 481.0
HFD1_k127_2483428_22 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 439.0
HFD1_k127_2483428_23 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 417.0
HFD1_k127_2483428_24 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 447.0
HFD1_k127_2483428_25 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 411.0
HFD1_k127_2483428_26 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 399.0
HFD1_k127_2483428_27 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 422.0
HFD1_k127_2483428_28 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 388.0
HFD1_k127_2483428_29 Glycosyltransferase family 28 N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 383.0
HFD1_k127_2483428_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.525e-220 698.0
HFD1_k127_2483428_30 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 367.0
HFD1_k127_2483428_31 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 362.0
HFD1_k127_2483428_32 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 349.0
HFD1_k127_2483428_33 PFAM major facilitator superfamily MFS_1 K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 348.0
HFD1_k127_2483428_34 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 334.0
HFD1_k127_2483428_35 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 342.0
HFD1_k127_2483428_36 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 347.0
HFD1_k127_2483428_37 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 342.0
HFD1_k127_2483428_38 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 360.0
HFD1_k127_2483428_39 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 328.0
HFD1_k127_2483428_4 Zinc-binding dehydrogenase - - - 7.102e-204 657.0
HFD1_k127_2483428_40 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 315.0
HFD1_k127_2483428_42 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 319.0
HFD1_k127_2483428_43 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 301.0
HFD1_k127_2483428_44 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 301.0
HFD1_k127_2483428_45 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 295.0
HFD1_k127_2483428_46 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 296.0
HFD1_k127_2483428_47 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 315.0
HFD1_k127_2483428_48 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 293.0
HFD1_k127_2483428_49 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 316.0
HFD1_k127_2483428_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 648.0
HFD1_k127_2483428_50 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 298.0
HFD1_k127_2483428_51 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 285.0
HFD1_k127_2483428_52 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 268.0
HFD1_k127_2483428_53 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001356 276.0
HFD1_k127_2483428_54 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001361 259.0
HFD1_k127_2483428_55 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009968 269.0
HFD1_k127_2483428_56 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002082 278.0
HFD1_k127_2483428_57 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000339 256.0
HFD1_k127_2483428_58 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000001621 263.0
HFD1_k127_2483428_59 Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003286 254.0
HFD1_k127_2483428_6 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 626.0
HFD1_k127_2483428_60 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000006041 247.0
HFD1_k127_2483428_61 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003187 252.0
HFD1_k127_2483428_62 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000005744 249.0
HFD1_k127_2483428_63 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000639 251.0
HFD1_k127_2483428_64 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000005835 231.0
HFD1_k127_2483428_65 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000009538 223.0
HFD1_k127_2483428_66 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000002238 231.0
HFD1_k127_2483428_67 D-glycero-D-manno-heptose 7-phosphate metabolic process K02843,K03271,K03273 - 3.1.3.82,3.1.3.83,5.3.1.28 0.0000000000000000000000000000000000000000000000000000009841 199.0
HFD1_k127_2483428_68 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000008301 200.0
HFD1_k127_2483428_69 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000000000004432 192.0
HFD1_k127_2483428_7 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 625.0
HFD1_k127_2483428_70 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000000000000344 184.0
HFD1_k127_2483428_71 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000003642 186.0
HFD1_k127_2483428_72 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000001203 194.0
HFD1_k127_2483428_73 recA bacterial DNA recombination protein - - - 0.0000000000000000000000000000000000000000000000002359 186.0
HFD1_k127_2483428_74 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000005348 177.0
HFD1_k127_2483428_75 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000002992 164.0
HFD1_k127_2483428_76 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000006018 169.0
HFD1_k127_2483428_77 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000001076 165.0
HFD1_k127_2483428_78 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000001827 156.0
HFD1_k127_2483428_79 Protein of unknown function (DUF2585) - - - 0.000000000000000000000000000000000003416 144.0
HFD1_k127_2483428_8 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 610.0
HFD1_k127_2483428_80 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000004016 146.0
HFD1_k127_2483428_81 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000005545 139.0
HFD1_k127_2483428_82 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000001325 139.0
HFD1_k127_2483428_83 MgtC family K07507 - - 0.0000000000000000000000000000001483 132.0
HFD1_k127_2483428_84 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000002488 132.0
HFD1_k127_2483428_85 Tetratricopeptide repeat - - - 0.000000000000000000000000000001078 139.0
HFD1_k127_2483428_86 Smr domain - - - 0.00000000000000000000000000005311 118.0
HFD1_k127_2483428_87 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000004258 123.0
HFD1_k127_2483428_88 Methyltransferase - - - 0.0000000000000000000000000106 119.0
HFD1_k127_2483428_89 Glycosyltransferase like family 2 - - - 0.00000000000000000000000006306 119.0
HFD1_k127_2483428_9 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 601.0
HFD1_k127_2483428_90 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000008371 119.0
HFD1_k127_2483428_91 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000001172 124.0
HFD1_k127_2483428_92 PIN domain - - - 0.0000000000000000000000006739 111.0
HFD1_k127_2483428_93 oxidoreductase activity - - - 0.0000000000000000000000008315 121.0
HFD1_k127_2483428_94 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.000000000000000000000002437 108.0
HFD1_k127_2483428_95 Transglycosylase SLT domain K08309 - - 0.000000000000000000000005406 108.0
HFD1_k127_2483428_97 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.00000000000000000000004491 106.0
HFD1_k127_2483428_98 Helix-turn-helix domain - - - 0.0000000000000000000003512 100.0
HFD1_k127_2483428_99 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000006871 98.0
HFD1_k127_2485238_0 Amino acid permease - - - 1.134e-240 767.0
HFD1_k127_2485238_1 serine threonine protein kinase K12132 - 2.7.11.1 3.588e-208 681.0
HFD1_k127_2485238_2 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 569.0
HFD1_k127_2485238_3 phosphorelay signal transduction system K02490 - - 0.00005115 51.0
HFD1_k127_2493791_0 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 511.0
HFD1_k127_2493791_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 502.0
HFD1_k127_2493791_10 domain protein - - - 0.000000000000000000000000001161 132.0
HFD1_k127_2493791_11 TIGRFAM Polymorphic membrane protein, Chlamydia - - - 0.0000000000000157 89.0
HFD1_k127_2493791_2 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 452.0
HFD1_k127_2493791_3 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 370.0
HFD1_k127_2493791_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002094 302.0
HFD1_k127_2493791_5 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007337 293.0
HFD1_k127_2493791_6 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.0000000000000000000000000000000000000000000000000000008119 201.0
HFD1_k127_2493791_7 Radical SAM K22227 - - 0.00000000000000000000000000000000000001524 159.0
HFD1_k127_2493791_8 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000005295 154.0
HFD1_k127_2493791_9 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.000000000000000000000000000001378 135.0
HFD1_k127_2506453_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.763e-280 871.0
HFD1_k127_2506453_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 1.314e-213 676.0
HFD1_k127_2548747_0 Peptidase M14, carboxypeptidase A - - - 0.0 1401.0
HFD1_k127_2548747_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1059.0
HFD1_k127_2548747_10 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 331.0
HFD1_k127_2548747_11 PFAM monooxygenase FAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 295.0
HFD1_k127_2548747_12 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
HFD1_k127_2548747_13 WG containing repeat - - - 0.00000000000000000000000000000000000000000000000000007391 200.0
HFD1_k127_2548747_14 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000001329 162.0
HFD1_k127_2548747_15 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000006646 133.0
HFD1_k127_2548747_16 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000005848 78.0
HFD1_k127_2548747_17 histidine kinase A domain protein - - - 0.000002576 55.0
HFD1_k127_2548747_2 Domain of unknown function (DUF5117) - - - 6.053e-285 898.0
HFD1_k127_2548747_3 Tetratricopeptide repeat - - - 2.887e-201 694.0
HFD1_k127_2548747_4 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 583.0
HFD1_k127_2548747_5 amine oxidase K00276 - 1.4.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 572.0
HFD1_k127_2548747_6 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 531.0
HFD1_k127_2548747_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 517.0
HFD1_k127_2548747_8 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 405.0
HFD1_k127_2548747_9 imidazolonepropionase activity K00466 - 1.13.12.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 339.0
HFD1_k127_2565573_0 Protein of unknown function (DUF3788) - - - 0.0000000000000000000000000000000000000000000002392 171.0
HFD1_k127_2565573_1 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000004981 141.0
HFD1_k127_2565573_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000001961 134.0
HFD1_k127_2565573_4 Domain of unknown function (DUF4440) - - - 0.0004464 51.0
HFD1_k127_2566109_0 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000000000583 223.0
HFD1_k127_2566109_1 PFAM NHL repeat containing protein K13735 - - 0.00006399 57.0
HFD1_k127_2572564_0 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 541.0
HFD1_k127_2572564_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 407.0
HFD1_k127_2587383_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 400.0
HFD1_k127_2587383_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000001788 119.0
HFD1_k127_2587383_2 PFAM O-antigen polymerase - - - 0.0000000000004983 83.0
HFD1_k127_2648903_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 458.0
HFD1_k127_2648903_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000005677 182.0
HFD1_k127_2704263_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.479e-219 709.0
HFD1_k127_2704263_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 400.0
HFD1_k127_2704263_2 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002145 282.0
HFD1_k127_2704263_3 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000003785 200.0
HFD1_k127_2704263_4 MoaC family K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000003655 188.0
HFD1_k127_2704263_5 metallopeptidase activity - - - 0.00000000000000000000000000000001099 138.0
HFD1_k127_2704263_6 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000003321 126.0
HFD1_k127_2704263_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000004776 123.0
HFD1_k127_2704263_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000004354 94.0
HFD1_k127_2704263_9 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000003449 66.0
HFD1_k127_2718604_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.718e-240 758.0
HFD1_k127_2718604_1 glutamine synthetase K01915 - 6.3.1.2 3.816e-206 650.0
HFD1_k127_2718604_10 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 312.0
HFD1_k127_2718604_11 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001214 287.0
HFD1_k127_2718604_12 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002983 277.0
HFD1_k127_2718604_13 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000002281 260.0
HFD1_k127_2718604_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007389 248.0
HFD1_k127_2718604_15 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000003312 239.0
HFD1_k127_2718604_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000987 240.0
HFD1_k127_2718604_17 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000001 234.0
HFD1_k127_2718604_18 Transport permease protein K09690 - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
HFD1_k127_2718604_19 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000006159 229.0
HFD1_k127_2718604_2 Calcineurin-like phosphoesterase - - - 1.389e-202 652.0
HFD1_k127_2718604_20 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000006871 197.0
HFD1_k127_2718604_21 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000008662 190.0
HFD1_k127_2718604_22 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001198 185.0
HFD1_k127_2718604_23 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000002905 181.0
HFD1_k127_2718604_24 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.00000000000000000000000000000000000000000000003106 174.0
HFD1_k127_2718604_25 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000002632 170.0
HFD1_k127_2718604_27 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000001108 151.0
HFD1_k127_2718604_28 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000002625 144.0
HFD1_k127_2718604_29 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000242 130.0
HFD1_k127_2718604_3 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 581.0
HFD1_k127_2718604_30 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000002906 134.0
HFD1_k127_2718604_31 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000003234 126.0
HFD1_k127_2718604_32 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000003612 127.0
HFD1_k127_2718604_33 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000004087 132.0
HFD1_k127_2718604_34 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000034 116.0
HFD1_k127_2718604_35 Tetratricopeptide repeat - - - 0.0000000000000000000000000005539 128.0
HFD1_k127_2718604_36 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000004761 115.0
HFD1_k127_2718604_37 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000189 116.0
HFD1_k127_2718604_38 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000289 108.0
HFD1_k127_2718604_39 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000007646 72.0
HFD1_k127_2718604_4 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 569.0
HFD1_k127_2718604_40 - - - - 0.00000004778 62.0
HFD1_k127_2718604_42 methyltransferase - - - 0.0000302 55.0
HFD1_k127_2718604_43 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00009176 48.0
HFD1_k127_2718604_5 COG2303 Choline dehydrogenase and related flavoproteins K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 533.0
HFD1_k127_2718604_6 threonine synthase activity K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 497.0
HFD1_k127_2718604_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 476.0
HFD1_k127_2718604_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 466.0
HFD1_k127_2718604_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007576 420.0
HFD1_k127_2724250_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.016e-296 930.0
HFD1_k127_2724250_1 proline dipeptidase activity K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 521.0
HFD1_k127_2724250_10 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000004057 211.0
HFD1_k127_2724250_11 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000002552 211.0
HFD1_k127_2724250_12 surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000002634 226.0
HFD1_k127_2724250_13 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000000000002679 192.0
HFD1_k127_2724250_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000005089 213.0
HFD1_k127_2724250_15 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000137 196.0
HFD1_k127_2724250_16 oxidoreductase activity K12511 - - 0.0000000000000000000000000000000000000000000001433 182.0
HFD1_k127_2724250_17 ATP-dependent protease La (LON) substrate-binding domain K01338 - 3.4.21.53 0.000000000000000000000000000000000000000001527 164.0
HFD1_k127_2724250_18 SET domain K07117 - - 0.0000000000000000000000000000000000000003899 152.0
HFD1_k127_2724250_19 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000001193 125.0
HFD1_k127_2724250_2 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 483.0
HFD1_k127_2724250_20 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000003552 113.0
HFD1_k127_2724250_21 Pfam:DUF490 K09800 - - 0.000000000000000000000009519 120.0
HFD1_k127_2724250_22 COG1145 Ferredoxin - - - 0.00000000000000000000015 98.0
HFD1_k127_2724250_23 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000001178 103.0
HFD1_k127_2724250_24 Pkd domain containing protein - - - 0.00000000003515 69.0
HFD1_k127_2724250_25 Domain of unknown function (DUF4149) - - - 0.000000007846 63.0
HFD1_k127_2724250_26 Domain of unknown function (DUF309) - - - 0.00000004591 61.0
HFD1_k127_2724250_27 - - - - 0.000006298 53.0
HFD1_k127_2724250_28 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0008826 50.0
HFD1_k127_2724250_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008992 454.0
HFD1_k127_2724250_4 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 405.0
HFD1_k127_2724250_5 Gluconolactonase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 365.0
HFD1_k127_2724250_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 346.0
HFD1_k127_2724250_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001804 278.0
HFD1_k127_2724250_8 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000316 240.0
HFD1_k127_2724250_9 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000001266 244.0
HFD1_k127_2864291_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 467.0
HFD1_k127_2864291_1 Forkhead associated domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 375.0
HFD1_k127_2864291_10 sequence-specific DNA binding - - - 0.0001095 50.0
HFD1_k127_2864291_2 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 343.0
HFD1_k127_2864291_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 336.0
HFD1_k127_2864291_4 Zn peptidase K21686 - - 0.00000000000000000000000000001014 126.0
HFD1_k127_2864291_5 von Willebrand factor, type A - - - 0.000000000000000000000003193 115.0
HFD1_k127_2864291_6 von Willebrand factor, type A - - - 0.00000000000000000003658 105.0
HFD1_k127_2864291_7 PFAM regulatory protein GntR HTH K07979 - - 0.00000000000000000005351 94.0
HFD1_k127_2864291_8 iron ion homeostasis - - - 0.000000000000000007353 95.0
HFD1_k127_2978964_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 313.0
HFD1_k127_2978964_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000005533 188.0
HFD1_k127_2989499_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 520.0
HFD1_k127_2989499_1 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 362.0
HFD1_k127_2989499_2 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006 269.0
HFD1_k127_2989499_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003293 263.0
HFD1_k127_2989499_4 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000002313 229.0
HFD1_k127_2989499_5 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000002171 201.0
HFD1_k127_2989499_6 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.000000000000000000000000000000000000000000000103 178.0
HFD1_k127_2989499_7 chlorophyll binding - - - 0.0000000000000000000000000000000000000001451 162.0
HFD1_k127_2989499_8 SnoaL-like domain - - - 0.000000000002644 72.0
HFD1_k127_2989499_9 Gluconokinase K00851 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0046316 2.7.1.12 0.0000000002195 64.0
HFD1_k127_3061417_0 Rhamnogalacturonan lyase B, N-terminal K18195 - 4.2.2.23 0.0 1940.0
HFD1_k127_3061417_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 427.0
HFD1_k127_3061417_2 S-acyltransferase activity K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 359.0
HFD1_k127_3061417_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 344.0
HFD1_k127_3061417_4 Major facilitator Superfamily K07785 - - 0.000000000000000000000000000000000000000000000000000000000000000000001933 251.0
HFD1_k127_3061417_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000000004229 103.0
HFD1_k127_3061417_6 heat shock protein binding - - - 0.0000000008767 69.0
HFD1_k127_3216289_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005853 229.0
HFD1_k127_3216289_1 xylan catabolic process K03932 - - 0.000000000000000000000000000000000000000000000000000001058 201.0
HFD1_k127_3216289_2 ABC transporter K01990 - - 0.0000000000000000000001266 98.0
HFD1_k127_3237210_0 in Yersinia the HmsR protein is an inner membrane protein K11936 - - 0.0 1179.0
HFD1_k127_3237210_1 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 518.0
HFD1_k127_3237210_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000001816 53.0
HFD1_k127_3237210_2 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 464.0
HFD1_k127_3237210_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001256 254.0
HFD1_k127_3237210_4 Domain of unknown function (DUF1287) K09974 - - 0.00000000000000000000000000000000000000000000000000000000000000813 223.0
HFD1_k127_3237210_6 SnoaL-like domain - - - 0.0000000000000000000000000000000000002847 145.0
HFD1_k127_3237210_7 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000002186 147.0
HFD1_k127_3237210_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000003519 108.0
HFD1_k127_3243755_0 PFAM Acetamidase Formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 460.0
HFD1_k127_3243755_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 350.0
HFD1_k127_3243755_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 328.0
HFD1_k127_3243755_3 Methyltransferase domain K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 308.0
HFD1_k127_3243755_4 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003557 258.0
HFD1_k127_3243755_5 PFAM Amidase - - - 0.0000000000000000000000000000000000000000000000000005504 188.0
HFD1_k127_3243755_6 PFAM OsmC family protein K04063 - - 0.0000000000000000000000000000000000000000000000004936 179.0
HFD1_k127_3243755_7 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000001798 126.0
HFD1_k127_3245634_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 6.575e-209 657.0
HFD1_k127_3245634_1 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 488.0
HFD1_k127_3245634_10 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000002067 162.0
HFD1_k127_3245634_11 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000001559 131.0
HFD1_k127_3245634_12 regulatory protein, MerR - - - 0.0000000000000000000000006594 110.0
HFD1_k127_3245634_13 Polysaccharide biosynthesis protein K12454 - 5.1.3.10 0.0000000000000000000000007932 115.0
HFD1_k127_3245634_14 Belongs to the 'phage' integrase family - - - 0.00000000000000000003811 98.0
HFD1_k127_3245634_15 Protein of unknown function (DUF3108) - - - 0.0000000000000002873 89.0
HFD1_k127_3245634_16 molecular chaperone K03686 - - 0.00000000000003661 83.0
HFD1_k127_3245634_17 Domain of unknown function (DUF4160) - - - 0.0000000000001539 71.0
HFD1_k127_3245634_18 HEAT repeat - - - 0.000000000001604 77.0
HFD1_k127_3245634_19 Subtilase family - - - 0.0000008977 53.0
HFD1_k127_3245634_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 471.0
HFD1_k127_3245634_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 466.0
HFD1_k127_3245634_4 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 455.0
HFD1_k127_3245634_5 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000644 260.0
HFD1_k127_3245634_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000009325 250.0
HFD1_k127_3245634_7 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000006972 232.0
HFD1_k127_3245634_8 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000000000000000000000000000000000000000000000002685 189.0
HFD1_k127_3245634_9 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000003719 165.0
HFD1_k127_3252684_0 Sortilin, neurotensin receptor 3, - - - 0.0 1442.0
HFD1_k127_3252684_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 509.0
HFD1_k127_3252684_10 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.00000000000000000000000003516 123.0
HFD1_k127_3252684_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 507.0
HFD1_k127_3252684_3 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 414.0
HFD1_k127_3252684_4 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 407.0
HFD1_k127_3252684_5 PFAM Basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 308.0
HFD1_k127_3252684_6 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003413 269.0
HFD1_k127_3252684_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000001244 180.0
HFD1_k127_3252684_8 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000006291 162.0
HFD1_k127_3252684_9 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000000000000000000001316 114.0
HFD1_k127_3254025_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.368e-227 712.0
HFD1_k127_3254025_1 Zinc carboxypeptidase - - - 5.549e-212 685.0
HFD1_k127_3254025_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000001591 110.0
HFD1_k127_3254025_11 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000003057 103.0
HFD1_k127_3254025_12 - - - - 0.0000006161 56.0
HFD1_k127_3254025_2 Amidase K01426 - 3.5.1.4 8.975e-211 672.0
HFD1_k127_3254025_3 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 340.0
HFD1_k127_3254025_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 327.0
HFD1_k127_3254025_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000001079 249.0
HFD1_k127_3254025_6 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000009383 240.0
HFD1_k127_3254025_7 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000001472 211.0
HFD1_k127_3254025_8 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000007677 141.0
HFD1_k127_3254025_9 transcriptional regulator containing an HTH domain and an K03655 - 3.6.4.12 0.00000000000000000000000000000000001187 152.0
HFD1_k127_3256669_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.328e-301 944.0
HFD1_k127_3256669_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 570.0
HFD1_k127_3256669_10 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000004011 170.0
HFD1_k127_3256669_11 peptidase K21471 - - 0.000000000000000000000000000000000000003517 158.0
HFD1_k127_3256669_12 cold-shock protein K03704 - - 0.0000000000000000000000004602 106.0
HFD1_k127_3256669_13 - - - - 0.00000000000000000000007435 108.0
HFD1_k127_3256669_14 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000002829 106.0
HFD1_k127_3256669_15 Hsp20/alpha crystallin family K13993 - - 0.00000000000002697 79.0
HFD1_k127_3256669_16 - - - - 0.000000000005668 75.0
HFD1_k127_3256669_17 Putative zinc-finger - - - 0.0003834 51.0
HFD1_k127_3256669_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 579.0
HFD1_k127_3256669_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 576.0
HFD1_k127_3256669_4 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 493.0
HFD1_k127_3256669_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 378.0
HFD1_k127_3256669_6 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000003646 247.0
HFD1_k127_3256669_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000001952 223.0
HFD1_k127_3256669_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001244 219.0
HFD1_k127_3256669_9 CHASE2 - - - 0.00000000000000000000000000000000000000000000000003159 202.0
HFD1_k127_3261439_0 Amidohydrolase family K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 617.0
HFD1_k127_3261439_1 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 565.0
HFD1_k127_3261439_10 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000001204 106.0
HFD1_k127_3261439_12 Domain of unknown function (DUF4328) - - - 0.000000000000000000009795 102.0
HFD1_k127_3261439_14 PFAM DNA polymerase beta domain protein region K07075 - - 0.0000007588 51.0
HFD1_k127_3261439_2 PFAM Peptidase S10, serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 552.0
HFD1_k127_3261439_3 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 501.0
HFD1_k127_3261439_4 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 496.0
HFD1_k127_3261439_5 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 475.0
HFD1_k127_3261439_6 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 443.0
HFD1_k127_3261439_7 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 443.0
HFD1_k127_3261439_8 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000003594 166.0
HFD1_k127_3261439_9 cellular response to heat K09807 - - 0.00000000000000000000000000000000175 138.0
HFD1_k127_3261485_0 Carboxypeptidase regulatory-like domain - - - 0.0 1111.0
HFD1_k127_3261485_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 3.7e-260 815.0
HFD1_k127_3261485_10 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000006681 226.0
HFD1_k127_3261485_11 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000002871 167.0
HFD1_k127_3261485_12 - - - - 0.0000000000000000000000000000000000000000005996 168.0
HFD1_k127_3261485_13 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000004322 153.0
HFD1_k127_3261485_14 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000001697 138.0
HFD1_k127_3261485_15 Methyltransferase domain - - - 0.0000000000000000000000000008058 117.0
HFD1_k127_3261485_16 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000001292 123.0
HFD1_k127_3261485_17 Transglutaminase-like superfamily - - - 0.0000000000000000001799 94.0
HFD1_k127_3261485_18 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000003806 68.0
HFD1_k127_3261485_19 SnoaL-like domain - - - 0.0000001239 57.0
HFD1_k127_3261485_2 PFAM Glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 7.203e-235 737.0
HFD1_k127_3261485_21 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0001147 53.0
HFD1_k127_3261485_3 Heparinase II/III-like protein - - - 1.211e-233 741.0
HFD1_k127_3261485_4 PFAM Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 541.0
HFD1_k127_3261485_5 CoA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 477.0
HFD1_k127_3261485_6 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 434.0
HFD1_k127_3261485_7 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 413.0
HFD1_k127_3261485_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002545 292.0
HFD1_k127_3261485_9 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000001012 250.0
HFD1_k127_3278258_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.497e-279 879.0
HFD1_k127_3278258_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 610.0
HFD1_k127_3278258_10 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000003553 81.0
HFD1_k127_3278258_12 Protein of unknown function (DUF983) - - - 0.0000000001746 66.0
HFD1_k127_3278258_14 integral membrane protein - - - 0.0000006521 59.0
HFD1_k127_3278258_2 Amidohydrolase family K01466 - 3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 546.0
HFD1_k127_3278258_3 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000181 273.0
HFD1_k127_3278258_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000007554 213.0
HFD1_k127_3278258_5 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K20446 - 1.17.1.5,1.2.5.3 0.000000000000000000000000000000000000000000000006423 176.0
HFD1_k127_3278258_6 serine threonine protein kinase - - - 0.000000000000000000000000003072 117.0
HFD1_k127_3278258_7 - - - - 0.0000000000000000000000001812 120.0
HFD1_k127_3278258_8 Thioesterase superfamily K07107 - - 0.000000000000000000000009775 106.0
HFD1_k127_3278258_9 - - - - 0.00000000000000003088 83.0
HFD1_k127_3282135_0 TonB dependent receptor - - - 2.233e-206 666.0
HFD1_k127_3287016_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 7.097e-248 814.0
HFD1_k127_3287016_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 3.208e-238 764.0
HFD1_k127_3287016_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000006404 78.0
HFD1_k127_3287016_11 D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.000000000378 71.0
HFD1_k127_3287016_12 - - - - 0.0000002265 54.0
HFD1_k127_3287016_13 WD40-like Beta Propeller Repeat - - - 0.00003119 51.0
HFD1_k127_3287016_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 314.0
HFD1_k127_3287016_3 including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 311.0
HFD1_k127_3287016_4 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000003934 182.0
HFD1_k127_3287016_5 HD domain - - - 0.000000000000000000000000000000006789 136.0
HFD1_k127_3287016_6 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000001537 119.0
HFD1_k127_3287016_7 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000004632 112.0
HFD1_k127_3287016_8 Probable zinc-ribbon domain - - - 0.0000000000000000000004913 100.0
HFD1_k127_3287016_9 Zinc metalloprotease (Elastase) - - - 0.000000000002236 82.0
HFD1_k127_3303681_0 transport - - - 0.0 1405.0
HFD1_k127_3303681_1 repeat protein - - - 7.861e-285 888.0
HFD1_k127_3303681_10 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 477.0
HFD1_k127_3303681_11 beta-N-acetylhexosaminidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 488.0
HFD1_k127_3303681_12 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 496.0
HFD1_k127_3303681_13 OmpA family K02557,K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 476.0
HFD1_k127_3303681_14 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 422.0
HFD1_k127_3303681_15 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 424.0
HFD1_k127_3303681_16 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 402.0
HFD1_k127_3303681_17 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 398.0
HFD1_k127_3303681_18 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 382.0
HFD1_k127_3303681_19 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 382.0
HFD1_k127_3303681_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.381e-253 804.0
HFD1_k127_3303681_20 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 377.0
HFD1_k127_3303681_21 4Fe-4S binding domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 376.0
HFD1_k127_3303681_22 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 297.0
HFD1_k127_3303681_23 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 319.0
HFD1_k127_3303681_24 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 269.0
HFD1_k127_3303681_25 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000003774 268.0
HFD1_k127_3303681_26 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
HFD1_k127_3303681_27 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000001521 244.0
HFD1_k127_3303681_28 TIGRFAM Small GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000001256 202.0
HFD1_k127_3303681_29 Glyoxalase-like domain K08234 - - 0.0000000000000000000000000000000000000000000000000000002811 198.0
HFD1_k127_3303681_3 Carboxypeptidase regulatory-like domain - - - 1.176e-236 775.0
HFD1_k127_3303681_30 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000009683 197.0
HFD1_k127_3303681_31 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000008382 188.0
HFD1_k127_3303681_32 - - - - 0.0000000000000000000000000000000000000003019 154.0
HFD1_k127_3303681_33 COGs COG4634 conserved - - - 0.000000000000000000000000000000000001644 141.0
HFD1_k127_3303681_34 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000001645 141.0
HFD1_k127_3303681_35 Protein conserved in bacteria - - - 0.00000000000000000000000000000000002387 142.0
HFD1_k127_3303681_36 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000000000003045 123.0
HFD1_k127_3303681_37 Protein of unknown function (DUF433) - - - 0.000000000000000000000000003562 113.0
HFD1_k127_3303681_38 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000001403 109.0
HFD1_k127_3303681_39 GYD domain - - - 0.000000000000000000000113 113.0
HFD1_k127_3303681_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.016e-222 696.0
HFD1_k127_3303681_40 mRNA binding K07339 - - 0.00000000000000000009419 89.0
HFD1_k127_3303681_41 PD-(D/E)XK nuclease superfamily - - - 0.000000000002035 70.0
HFD1_k127_3303681_44 lactate metabolic process K11473 - - 0.000001676 54.0
HFD1_k127_3303681_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 610.0
HFD1_k127_3303681_6 Belongs to the glycosyl hydrolase 28 family K15532 - 3.2.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 582.0
HFD1_k127_3303681_7 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 578.0
HFD1_k127_3303681_8 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 562.0
HFD1_k127_3303681_9 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 553.0
HFD1_k127_3311375_0 iron-nicotianamine transmembrane transporter activity - - - 3.966e-285 899.0
HFD1_k127_3311375_1 (ABC) transporter K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 599.0
HFD1_k127_3311375_10 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000000006164 167.0
HFD1_k127_3311375_11 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000008897 173.0
HFD1_k127_3311375_12 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000007012 121.0
HFD1_k127_3311375_13 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.0000000000000000000003083 100.0
HFD1_k127_3311375_14 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000001188 67.0
HFD1_k127_3311375_15 Protein of unknown function (DUF2490) - - - 0.00001318 55.0
HFD1_k127_3311375_2 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 590.0
HFD1_k127_3311375_3 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 450.0
HFD1_k127_3311375_4 aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 446.0
HFD1_k127_3311375_5 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 298.0
HFD1_k127_3311375_6 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000001901 203.0
HFD1_k127_3311375_7 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000754 193.0
HFD1_k127_3311375_8 Sulfate ABC transporter inner membrane subunit CysW K02047 - - 0.0000000000000000000000000000000000000000000000002094 186.0
HFD1_k127_3311375_9 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000007032 182.0
HFD1_k127_3364294_0 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.0 1462.0
HFD1_k127_3364294_1 Glycosyl hydrolase family 3 K05349 - 3.2.1.21 2.03e-322 1009.0
HFD1_k127_3364294_10 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 576.0
HFD1_k127_3364294_11 Alginate lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 539.0
HFD1_k127_3364294_12 PFAM Alcohol dehydrogenase GroES-like domain K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 481.0
HFD1_k127_3364294_13 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 455.0
HFD1_k127_3364294_14 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 451.0
HFD1_k127_3364294_15 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 431.0
HFD1_k127_3364294_16 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 430.0
HFD1_k127_3364294_17 Alginate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 360.0
HFD1_k127_3364294_18 Hydroxysteroid (17-beta) dehydrogenase 14 K00826 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006694,GO:0006703,GO:0006706,GO:0008150,GO:0008152,GO:0008202,GO:0008210,GO:0008610,GO:0009056,GO:0009058,GO:0009987,GO:0010817,GO:0016042,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0033764,GO:0034754,GO:0042445,GO:0042446,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0047045,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 331.0
HFD1_k127_3364294_19 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 308.0
HFD1_k127_3364294_2 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 9.914e-307 961.0
HFD1_k127_3364294_20 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 310.0
HFD1_k127_3364294_21 amidohydrolase K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 291.0
HFD1_k127_3364294_22 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 287.0
HFD1_k127_3364294_23 G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008997 280.0
HFD1_k127_3364294_24 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 274.0
HFD1_k127_3364294_25 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007022 243.0
HFD1_k127_3364294_26 Peptidase of plants and bacteria - - - 0.0000000000000000000000000000000000000000000000000004827 196.0
HFD1_k127_3364294_3 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 6.874e-240 760.0
HFD1_k127_3364294_4 protocatechuate 3,4-dioxygenase activity - - - 1.387e-228 751.0
HFD1_k127_3364294_5 Psort location Cytoplasmic, score - - - 1.041e-218 700.0
HFD1_k127_3364294_6 TonB-dependent receptor - - - 7.769e-214 713.0
HFD1_k127_3364294_7 carboxylic acid catabolic process K18334 - 4.2.1.68 2.784e-209 658.0
HFD1_k127_3364294_8 PFAM glycoside hydrolase, family 29 K01206 - 3.2.1.51 8.615e-209 656.0
HFD1_k127_3364294_9 Right handed beta helix region - - - 2.896e-201 640.0
HFD1_k127_3409126_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 574.0
HFD1_k127_3409126_1 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 517.0
HFD1_k127_3409126_10 - - - - 0.00006371 46.0
HFD1_k127_3409126_2 aminotransferase class I and II K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 530.0
HFD1_k127_3409126_3 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 523.0
HFD1_k127_3409126_4 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 292.0
HFD1_k127_3409126_5 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000811 211.0
HFD1_k127_3409126_6 Transposase IS200 like K07445 - - 0.000000000000000000000000000000000000000000000000002747 190.0
HFD1_k127_3409126_7 Protein of unknown function (DUF1203) - - - 0.000000000000000000000000000000000000000000000000009 184.0
HFD1_k127_3409126_8 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000001281 160.0
HFD1_k127_3409126_9 metallopeptidase activity K07404 - 3.1.1.31 0.000000000000002853 90.0
HFD1_k127_3417168_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.14e-214 678.0
HFD1_k127_3417168_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 526.0
HFD1_k127_3417168_10 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002455 290.0
HFD1_k127_3417168_11 Tricorn protease C1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001786 281.0
HFD1_k127_3417168_12 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008811 269.0
HFD1_k127_3417168_13 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001001 261.0
HFD1_k127_3417168_14 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001041 258.0
HFD1_k127_3417168_15 enterobactin catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002275 253.0
HFD1_k127_3417168_16 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000001407 250.0
HFD1_k127_3417168_17 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000779 228.0
HFD1_k127_3417168_18 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000335 212.0
HFD1_k127_3417168_19 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000003944 200.0
HFD1_k127_3417168_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 509.0
HFD1_k127_3417168_20 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000002559 201.0
HFD1_k127_3417168_21 sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000007058 182.0
HFD1_k127_3417168_22 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000001273 182.0
HFD1_k127_3417168_23 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000005028 184.0
HFD1_k127_3417168_24 - - - - 0.000000000000000000000000000001674 125.0
HFD1_k127_3417168_25 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.00000000000000000000000000000749 133.0
HFD1_k127_3417168_26 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000004203 127.0
HFD1_k127_3417168_27 Phosphatidylglycerophosphatase A K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.000000000000000000000003137 111.0
HFD1_k127_3417168_28 ErfK YbiS YcfS YnhG K16291 - - 0.00000000000001998 86.0
HFD1_k127_3417168_29 SNARE associated Golgi protein - - - 0.000000000001079 75.0
HFD1_k127_3417168_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 432.0
HFD1_k127_3417168_30 von Willebrand factor, type A K07114 - - 0.0000000341 66.0
HFD1_k127_3417168_31 PAP2 superfamily - - - 0.000003812 51.0
HFD1_k127_3417168_32 - - - - 0.000005043 59.0
HFD1_k127_3417168_33 - - - - 0.00005876 49.0
HFD1_k127_3417168_34 Serine aminopeptidase, S33 K00433,K01259 - 1.11.1.10,3.4.11.5 0.0001879 47.0
HFD1_k127_3417168_35 WD40 domain protein beta Propeller - - - 0.0002065 44.0
HFD1_k127_3417168_36 Peptidase family M1 domain - - - 0.0009926 52.0
HFD1_k127_3417168_4 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 414.0
HFD1_k127_3417168_5 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 367.0
HFD1_k127_3417168_6 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 356.0
HFD1_k127_3417168_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 334.0
HFD1_k127_3417168_8 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 316.0
HFD1_k127_3417168_9 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 286.0
HFD1_k127_3418477_0 Carboxypeptidase regulatory-like domain - - - 0.0 1144.0
HFD1_k127_3418477_1 hydrolase, family 3 K05349 - 3.2.1.21 6.919e-281 881.0
HFD1_k127_3418477_10 carbohydrate transport K10544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 385.0
HFD1_k127_3418477_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000004983 227.0
HFD1_k127_3418477_12 - - - - 0.00000000000000000000000000000000000000000000000000000000005393 220.0
HFD1_k127_3418477_13 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000003249 211.0
HFD1_k127_3418477_14 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000335 194.0
HFD1_k127_3418477_15 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000002414 160.0
HFD1_k127_3418477_16 FR47-like protein - - - 0.00000000000000000000000000000003331 131.0
HFD1_k127_3418477_17 Putative adhesin - - - 0.00000000000000000000000009864 118.0
HFD1_k127_3418477_19 ECF sigma factor K03088 - - 0.0000000000000001583 86.0
HFD1_k127_3418477_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 8.152e-259 816.0
HFD1_k127_3418477_20 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000002867 79.0
HFD1_k127_3418477_21 SnoaL-like domain - - - 0.00000000009454 68.0
HFD1_k127_3418477_22 Aminotransferase class I and II K00375 - - 0.0000009537 55.0
HFD1_k127_3418477_23 - - - - 0.000003396 49.0
HFD1_k127_3418477_24 Transposase (IS116 IS110 IS902 family) K07486 - - 0.000005769 48.0
HFD1_k127_3418477_25 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00001482 52.0
HFD1_k127_3418477_3 Prolyl oligopeptidase family - - - 3.092e-214 685.0
HFD1_k127_3418477_4 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 2.082e-201 631.0
HFD1_k127_3418477_5 Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system K10441,K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 587.0
HFD1_k127_3418477_6 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 509.0
HFD1_k127_3418477_7 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 515.0
HFD1_k127_3418477_8 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 431.0
HFD1_k127_3418477_9 Periplasmic binding protein domain K02058,K10543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 406.0
HFD1_k127_3461174_0 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 427.0
HFD1_k127_3461174_1 transporter - - - 0.000000000000000000000000000000000000000000000000000004167 195.0
HFD1_k127_3461174_2 chitinase activity - - - 0.000000000000000000000000000000000489 151.0
HFD1_k127_3461174_3 ECF sigma factor - - - 0.000000000000000000000000003705 114.0
HFD1_k127_3461174_4 RNA polymerase sigma factor, sigma-70 family - - - 0.00000000000000000000000001544 123.0
HFD1_k127_3461174_5 exo-alpha-(2->6)-sialidase activity - - - 0.00000002887 66.0
HFD1_k127_3470660_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.749e-302 968.0
HFD1_k127_3470660_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 481.0
HFD1_k127_3470660_2 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000001723 192.0
HFD1_k127_3470660_3 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000001804 175.0
HFD1_k127_3470660_4 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000003247 134.0
HFD1_k127_3470660_5 RNA-binding S4 domain protein - - - 0.00000000000000004417 84.0
HFD1_k127_3470660_6 Glycosyl transferase family 41 - - - 0.000000003742 69.0
HFD1_k127_3470660_7 - - - - 0.0000005244 56.0
HFD1_k127_3495925_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0 1016.0
HFD1_k127_3495925_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.633e-307 959.0
HFD1_k127_3495925_10 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 458.0
HFD1_k127_3495925_11 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 426.0
HFD1_k127_3495925_12 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 362.0
HFD1_k127_3495925_13 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 365.0
HFD1_k127_3495925_14 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 347.0
HFD1_k127_3495925_15 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 323.0
HFD1_k127_3495925_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006206 273.0
HFD1_k127_3495925_17 Bacteriocin-protection protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000308 228.0
HFD1_k127_3495925_18 - - - - 0.0000000000000000000000000000000000000000000000000000002064 197.0
HFD1_k127_3495925_19 Metallo-beta-lactamase superfamily - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 - 0.00000000000000000000000000000000000000000000000000003967 195.0
HFD1_k127_3495925_2 GTP-binding protein TypA K06207 - - 1.539e-255 800.0
HFD1_k127_3495925_20 TIGRFAM addiction module toxin, Txe YoeB family K19158 - - 0.0000000000000000000000000000000000000005416 150.0
HFD1_k127_3495925_21 lipolytic protein G-D-S-L family K01186 - 3.2.1.18 0.000000000000000000000000000000002086 138.0
HFD1_k127_3495925_22 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000083 136.0
HFD1_k127_3495925_23 Methyltransferase domain - - - 0.0000000000000000000000000000004819 130.0
HFD1_k127_3495925_24 membrane - - - 0.000000000000000000000000000004649 122.0
HFD1_k127_3495925_25 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000006791 111.0
HFD1_k127_3495925_26 Methyltransferase domain - - - 0.00000000000000008021 90.0
HFD1_k127_3495925_27 Tetratricopeptide repeat - - - 0.00000000000000112 80.0
HFD1_k127_3495925_28 WbqC-like protein family - - - 0.00000000000001423 75.0
HFD1_k127_3495925_29 - - - - 0.0000000000000233 79.0
HFD1_k127_3495925_3 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 1.488e-209 666.0
HFD1_k127_3495925_30 lysyltransferase activity K07027 - - 0.00000000001383 76.0
HFD1_k127_3495925_31 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000001164 64.0
HFD1_k127_3495925_32 Methionine biosynthesis protein MetW - - - 0.000000002673 68.0
HFD1_k127_3495925_33 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000348 70.0
HFD1_k127_3495925_34 protein kinase activity - - - 0.0000000634 59.0
HFD1_k127_3495925_35 Domain of unknown function (DUF4440) - - - 0.00000448 58.0
HFD1_k127_3495925_36 Periplasmic or secreted lipoprotein - - - 0.00007439 46.0
HFD1_k127_3495925_37 RNA polymerase-associated protein CTR9 homolog K15176 GO:0000122,GO:0000428,GO:0000785,GO:0000993,GO:0001098,GO:0001099,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0008023,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009909,GO:0009910,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0016020,GO:0016043,GO:0016569,GO:0016570,GO:0016571,GO:0016591,GO:0016593,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0030880,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032270,GO:0032784,GO:0032786,GO:0032968,GO:0032991,GO:0033043,GO:0033044,GO:0034243,GO:0034968,GO:0035327,GO:0036211,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048581,GO:0048831,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051569,GO:0051571,GO:0055029,GO:0060255,GO:0061695,GO:0065007,GO:0070013,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0080182,GO:1901564,GO:1902275,GO:1902494,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1905269,GO:1990234,GO:2000026,GO:2000112,GO:2000113,GO:2000241,GO:2000242,GO:2001141,GO:2001252 - 0.0003173 53.0
HFD1_k127_3495925_38 Belongs to the ompA family - - - 0.0007971 51.0
HFD1_k127_3495925_4 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 553.0
HFD1_k127_3495925_5 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 499.0
HFD1_k127_3495925_6 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 490.0
HFD1_k127_3495925_7 PFAM NAD-dependent epimerase dehydratase K01710,K01784,K02473,K08678 - 4.1.1.35,4.2.1.46,5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 484.0
HFD1_k127_3495925_8 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 477.0
HFD1_k127_3495925_9 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 481.0
HFD1_k127_3501274_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 4.293e-295 927.0
HFD1_k127_3501274_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.219e-262 828.0
HFD1_k127_3501274_10 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 388.0
HFD1_k127_3501274_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 384.0
HFD1_k127_3501274_12 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 372.0
HFD1_k127_3501274_13 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 357.0
HFD1_k127_3501274_14 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 322.0
HFD1_k127_3501274_15 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 340.0
HFD1_k127_3501274_16 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 305.0
HFD1_k127_3501274_17 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 302.0
HFD1_k127_3501274_18 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000001635 274.0
HFD1_k127_3501274_19 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000269 255.0
HFD1_k127_3501274_2 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 7.647e-259 812.0
HFD1_k127_3501274_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002087 224.0
HFD1_k127_3501274_21 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000003945 200.0
HFD1_k127_3501274_22 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000002417 182.0
HFD1_k127_3501274_23 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000311 186.0
HFD1_k127_3501274_24 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000391 158.0
HFD1_k127_3501274_25 ) H( ) antiporter that extrudes sodium in exchange for external protons - - - 0.00000000000000000000000000000000000006843 151.0
HFD1_k127_3501274_26 MerR HTH family regulatory protein K13640 - - 0.0000000000000000000000000000000000006849 146.0
HFD1_k127_3501274_27 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000001347 137.0
HFD1_k127_3501274_28 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.000000000000000000000000000005428 126.0
HFD1_k127_3501274_29 triphosphatase activity - - - 0.00000000000000000000000006148 114.0
HFD1_k127_3501274_3 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 577.0
HFD1_k127_3501274_30 - - - - 0.0000000000000000000000001716 109.0
HFD1_k127_3501274_31 von Willebrand factor, type A - - - 0.0000000000000000000000002681 122.0
HFD1_k127_3501274_32 Protein of unknown function (DUF3298) - - - 0.0000000000000000000001296 111.0
HFD1_k127_3501274_33 Lanthionine synthetase C family protein - - - 0.0000000000000000000001827 113.0
HFD1_k127_3501274_34 Thioredoxin - - - 0.0000000000000000000009512 101.0
HFD1_k127_3501274_35 HxlR-like helix-turn-helix - - - 0.000000000000000000001891 99.0
HFD1_k127_3501274_36 oxidoreductase activity K00274 - 1.4.3.4 0.000000000000000000003545 99.0
HFD1_k127_3501274_37 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000003918 94.0
HFD1_k127_3501274_38 Protein of unknown function (DUF2905) - - - 0.000000000000000004397 86.0
HFD1_k127_3501274_39 Domain of unknown function (DUF4870) - - - 0.000000000000002267 82.0
HFD1_k127_3501274_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 590.0
HFD1_k127_3501274_41 Domain of unknown function (DUF4870) - - - 0.00000000007084 72.0
HFD1_k127_3501274_42 Vitamin k epoxide reductase - - - 0.0000000009854 66.0
HFD1_k127_3501274_43 TPM domain K06872 - - 0.0000000281 68.0
HFD1_k127_3501274_44 Carboxypeptidase regulatory-like domain - - - 0.0000001822 64.0
HFD1_k127_3501274_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 541.0
HFD1_k127_3501274_6 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 532.0
HFD1_k127_3501274_7 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 511.0
HFD1_k127_3501274_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 428.0
HFD1_k127_3501274_9 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 413.0
HFD1_k127_3523787_0 PFAM Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 419.0
HFD1_k127_3523787_1 - - - - 0.000000000000000000003029 96.0
HFD1_k127_3556027_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1293.0
HFD1_k127_3556027_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 535.0
HFD1_k127_3556027_11 Transposase IS200 like - - - 0.0000000001 64.0
HFD1_k127_3556027_12 - - - - 0.00002037 54.0
HFD1_k127_3556027_2 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 439.0
HFD1_k127_3556027_3 cobalamin-transporting ATPase activity K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 415.0
HFD1_k127_3556027_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006207 256.0
HFD1_k127_3556027_5 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000006399 216.0
HFD1_k127_3556027_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000125 192.0
HFD1_k127_3556027_7 PFAM Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000000002265 186.0
HFD1_k127_3556027_8 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03767,K03768,K09565 - 5.2.1.8 0.000000000000000000000000000000002319 138.0
HFD1_k127_3556027_9 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000008731 136.0
HFD1_k127_3576779_0 Radical SAM - - - 1e-323 1003.0
HFD1_k127_3576779_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000001622 242.0
HFD1_k127_3576779_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000939 196.0
HFD1_k127_3576779_3 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000008983 78.0
HFD1_k127_3633475_0 Tricorn protease C1 domain K08676 - - 0.0 1310.0
HFD1_k127_3633475_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 7.077e-295 937.0
HFD1_k127_3633475_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 512.0
HFD1_k127_3633475_11 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 496.0
HFD1_k127_3633475_12 bacterial-type flagellum-dependent cell motility K20951,K20952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 470.0
HFD1_k127_3633475_13 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 453.0
HFD1_k127_3633475_14 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 456.0
HFD1_k127_3633475_15 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 453.0
HFD1_k127_3633475_16 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 444.0
HFD1_k127_3633475_17 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 428.0
HFD1_k127_3633475_18 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 422.0
HFD1_k127_3633475_19 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 409.0
HFD1_k127_3633475_2 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 1.061e-291 913.0
HFD1_k127_3633475_20 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 375.0
HFD1_k127_3633475_21 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 392.0
HFD1_k127_3633475_22 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 411.0
HFD1_k127_3633475_23 YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 374.0
HFD1_k127_3633475_24 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 355.0
HFD1_k127_3633475_25 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 359.0
HFD1_k127_3633475_26 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 369.0
HFD1_k127_3633475_27 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009855 360.0
HFD1_k127_3633475_28 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 333.0
HFD1_k127_3633475_29 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 313.0
HFD1_k127_3633475_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.438e-232 727.0
HFD1_k127_3633475_30 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 299.0
HFD1_k127_3633475_31 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001003 289.0
HFD1_k127_3633475_32 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008753 282.0
HFD1_k127_3633475_33 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005098 286.0
HFD1_k127_3633475_34 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002819 296.0
HFD1_k127_3633475_35 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000005542 265.0
HFD1_k127_3633475_36 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000003828 227.0
HFD1_k127_3633475_37 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000002404 213.0
HFD1_k127_3633475_38 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000000003085 210.0
HFD1_k127_3633475_39 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000002553 198.0
HFD1_k127_3633475_4 Radical SAM - - - 2.542e-212 678.0
HFD1_k127_3633475_40 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000001268 200.0
HFD1_k127_3633475_41 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000001065 189.0
HFD1_k127_3633475_42 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000001976 169.0
HFD1_k127_3633475_43 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000000000000000000000002801 180.0
HFD1_k127_3633475_44 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000002387 169.0
HFD1_k127_3633475_45 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000001099 162.0
HFD1_k127_3633475_46 electron transfer activity - - - 0.0000000000000000000000000000000000000001763 168.0
HFD1_k127_3633475_47 YHS domain K06966 - 3.2.2.10 0.000000000000000000000000000000000000002175 152.0
HFD1_k127_3633475_48 - - - - 0.00000000000000000000000000000000001923 153.0
HFD1_k127_3633475_49 outer membrane efflux protein - - - 0.00000000000000000000000000000000004711 151.0
HFD1_k127_3633475_5 NADH oxidase - - - 2.545e-211 667.0
HFD1_k127_3633475_50 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000129 136.0
HFD1_k127_3633475_51 - - - - 0.000000000000000000000000000000003131 133.0
HFD1_k127_3633475_52 DinB superfamily - - - 0.00000000000000000000001499 108.0
HFD1_k127_3633475_53 Transposase K07491 - - 0.00000000000000000000003289 102.0
HFD1_k127_3633475_54 Universal stress protein - - - 0.0000000000000000000004104 102.0
HFD1_k127_3633475_55 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000004948 98.0
HFD1_k127_3633475_57 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000005666 102.0
HFD1_k127_3633475_58 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000001004 98.0
HFD1_k127_3633475_59 - - - - 0.000000000000000003832 87.0
HFD1_k127_3633475_6 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 579.0
HFD1_k127_3633475_60 Transposase IS200 like - - - 0.0000000000000001142 83.0
HFD1_k127_3633475_61 - - - - 0.00000000004033 72.0
HFD1_k127_3633475_62 GDSL-like Lipase/Acylhydrolase - - - 0.0000000003874 71.0
HFD1_k127_3633475_63 lytic transglycosylase activity K03194 - - 0.000000001506 70.0
HFD1_k127_3633475_64 Transcriptional regulator K03641 - - 0.0000002747 55.0
HFD1_k127_3633475_65 - - - - 0.000008518 51.0
HFD1_k127_3633475_66 - - - - 0.0001254 50.0
HFD1_k127_3633475_67 PFAM IstB domain protein ATP-binding protein - - - 0.0001727 45.0
HFD1_k127_3633475_68 SNARE associated Golgi protein - - - 0.0005764 50.0
HFD1_k127_3633475_7 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 531.0
HFD1_k127_3633475_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 530.0
HFD1_k127_3633475_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 540.0
HFD1_k127_3690478_0 GlnD PII-uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 460.0
HFD1_k127_3690478_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 401.0
HFD1_k127_3690478_2 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751 - - 0.00000000000000000000000000000000000000000004904 163.0
HFD1_k127_369098_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.35e-266 827.0
HFD1_k127_369098_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 603.0
HFD1_k127_369098_10 ECF sigma factor - - - 0.000000000000000002685 87.0
HFD1_k127_369098_11 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000002721 81.0
HFD1_k127_369098_12 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000007706 76.0
HFD1_k127_369098_13 Lactonase, 7-bladed beta-propeller - - - 0.000000000001497 76.0
HFD1_k127_369098_14 PFAM Transposase DDE domain - - - 0.000000003417 59.0
HFD1_k127_369098_15 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000009526 59.0
HFD1_k127_369098_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009919 555.0
HFD1_k127_369098_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 539.0
HFD1_k127_369098_4 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 434.0
HFD1_k127_369098_5 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000286 256.0
HFD1_k127_369098_6 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000002407 219.0
HFD1_k127_369098_7 - - - - 0.0000000000000000000000000000000000000000000000000000000001016 215.0
HFD1_k127_369098_8 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000000007344 209.0
HFD1_k127_369098_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000004615 142.0
HFD1_k127_3714816_0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000002618 211.0
HFD1_k127_3714816_1 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000002003 142.0
HFD1_k127_3714816_2 PFAM UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.0000000000000000000000001388 120.0
HFD1_k127_3742354_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 382.0
HFD1_k127_3742354_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 287.0
HFD1_k127_3742354_10 PFAM Nickel cobalt transporter, high-affinity - - - 0.000000000000000000000000000000000000000000000003043 181.0
HFD1_k127_3742354_11 protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000000000000000000000001507 157.0
HFD1_k127_3742354_12 Membrane - - - 0.0000000000000000000000000000002113 128.0
HFD1_k127_3742354_13 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000002982 119.0
HFD1_k127_3742354_14 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.0000000000000000000006886 101.0
HFD1_k127_3742354_15 PQQ enzyme repeat - - - 0.0000000000000000002905 99.0
HFD1_k127_3742354_16 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 - 1.12.99.6 0.0000000000000004161 81.0
HFD1_k127_3742354_17 -O-antigen K02847 - - 0.0000000000004154 83.0
HFD1_k127_3742354_19 - - - - 0.00000000009761 68.0
HFD1_k127_3742354_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 289.0
HFD1_k127_3742354_20 cAMP biosynthetic process - - - 0.0000006023 54.0
HFD1_k127_3742354_21 Belongs to the UPF0312 family - - - 0.00005585 53.0
HFD1_k127_3742354_22 LysM domain - - - 0.00006125 48.0
HFD1_k127_3742354_23 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000171 44.0
HFD1_k127_3742354_3 BtpA family K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 286.0
HFD1_k127_3742354_4 Succinylglutamate desuccinylase / Aspartoacylase family K05526 - 3.5.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000003804 273.0
HFD1_k127_3742354_5 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000001793 243.0
HFD1_k127_3742354_6 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009847 237.0
HFD1_k127_3742354_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
HFD1_k127_3742354_8 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000008904 207.0
HFD1_k127_3742354_9 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000004901 184.0
HFD1_k127_3875483_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1058.0
HFD1_k127_3875483_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 2.209e-292 915.0
HFD1_k127_3875483_10 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 349.0
HFD1_k127_3875483_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 312.0
HFD1_k127_3875483_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006632 250.0
HFD1_k127_3875483_13 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001631 281.0
HFD1_k127_3875483_14 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000005205 236.0
HFD1_k127_3875483_15 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000003476 232.0
HFD1_k127_3875483_16 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001473 213.0
HFD1_k127_3875483_17 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000000000263 202.0
HFD1_k127_3875483_18 - - - - 0.000000000000000000000000000000000000000000000000000004098 198.0
HFD1_k127_3875483_19 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000000000002321 190.0
HFD1_k127_3875483_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 497.0
HFD1_k127_3875483_20 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000000000000000000000000000000000000000003118 195.0
HFD1_k127_3875483_21 DoxX-like family - - - 0.0000000000000000000000000000000000000000000000008949 177.0
HFD1_k127_3875483_22 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000001405 174.0
HFD1_k127_3875483_23 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000001714 198.0
HFD1_k127_3875483_24 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.0000000000000000000000000000000000000000004025 162.0
HFD1_k127_3875483_25 - - - - 0.000000000000000000000000000000001092 133.0
HFD1_k127_3875483_26 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000001147 132.0
HFD1_k127_3875483_27 Domain of unknown function (DU1801) - - - 0.00000000000000000000000009841 112.0
HFD1_k127_3875483_28 PFAM Iron permease FTR1 K07243 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000002333 102.0
HFD1_k127_3875483_29 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000206 79.0
HFD1_k127_3875483_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 490.0
HFD1_k127_3875483_31 Redoxin - - - 0.00000000000468 70.0
HFD1_k127_3875483_32 Protein of unknown function (DUF3108) - - - 0.0000000002552 73.0
HFD1_k127_3875483_33 Protein of unknown function (DUF3108) - - - 0.00000001668 67.0
HFD1_k127_3875483_34 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00005434 54.0
HFD1_k127_3875483_4 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 451.0
HFD1_k127_3875483_5 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 459.0
HFD1_k127_3875483_6 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 421.0
HFD1_k127_3875483_7 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 406.0
HFD1_k127_3875483_8 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 407.0
HFD1_k127_3875483_9 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 364.0
HFD1_k127_3913150_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 514.0
HFD1_k127_3913150_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000958 265.0
HFD1_k127_3913150_10 Domain of unknown function DUF11 - - - 0.00000000000000000000938 109.0
HFD1_k127_3913150_11 Periplasmic or secreted lipoprotein - - - 0.000000000000002405 84.0
HFD1_k127_3913150_12 CBD_II K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000000008518 73.0
HFD1_k127_3913150_14 Lipid A 3-O-deacylase (PagL) - - - 0.000778 46.0
HFD1_k127_3913150_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000002625 229.0
HFD1_k127_3913150_3 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000003362 205.0
HFD1_k127_3913150_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000002705 176.0
HFD1_k127_3913150_5 TIGRFAM molybdenum cofactor synthesis - - - 0.00000000000000000000000000000000000000000001239 167.0
HFD1_k127_3913150_6 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.0000000000000000000000000000000002641 154.0
HFD1_k127_3913150_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000002034 131.0
HFD1_k127_3913150_8 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000002091 148.0
HFD1_k127_3913150_9 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000938 128.0
HFD1_k127_3914824_0 lipopolysaccharide transport K22110 - - 0.0 1446.0
HFD1_k127_3914824_1 choline dehydrogenase activity - - - 7.833e-265 822.0
HFD1_k127_3914824_2 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 548.0
HFD1_k127_3914824_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 459.0
HFD1_k127_3914824_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 334.0
HFD1_k127_3914824_5 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 295.0
HFD1_k127_3914824_6 - - - - 0.000000000000000000000000000000000000000000000000000004167 195.0
HFD1_k127_3914824_7 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000001514 201.0
HFD1_k127_3914824_8 Domain of unknown function (DUF4440) - - - 0.00000007001 59.0
HFD1_k127_3969770_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 553.0
HFD1_k127_3969770_1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000002774 231.0
HFD1_k127_3969770_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001101 198.0
HFD1_k127_3969770_3 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000000000000000001271 196.0
HFD1_k127_3969770_4 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000001204 179.0
HFD1_k127_3969770_5 YCII-related domain - - - 0.0000000000000000000000000000000000000003891 151.0
HFD1_k127_3969770_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000004819 153.0
HFD1_k127_3969770_7 YCII-related domain - - - 0.0000000000000000000000000000001589 128.0
HFD1_k127_3975539_0 Dienelactone hydrolase family - - - 3.378e-265 843.0
HFD1_k127_3975539_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.646e-252 797.0
HFD1_k127_3975539_10 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000004021 190.0
HFD1_k127_3975539_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000002461 153.0
HFD1_k127_3975539_12 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000008212 109.0
HFD1_k127_3975539_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000002225 106.0
HFD1_k127_3975539_14 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000001127 91.0
HFD1_k127_3975539_15 TIGRFAM TonB K03832 - - 0.0000000000000001507 89.0
HFD1_k127_3975539_16 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000002109 74.0
HFD1_k127_3975539_18 Tetratricopeptide repeat - - - 0.0000000009745 69.0
HFD1_k127_3975539_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 449.0
HFD1_k127_3975539_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 422.0
HFD1_k127_3975539_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 384.0
HFD1_k127_3975539_5 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 326.0
HFD1_k127_3975539_6 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005081 269.0
HFD1_k127_3975539_7 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005793 277.0
HFD1_k127_3975539_8 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 272.0
HFD1_k127_3975539_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001372 252.0
HFD1_k127_3986999_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 301.0
HFD1_k127_3986999_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000001016 146.0
HFD1_k127_3986999_2 S23 ribosomal protein - - - 0.00000000000000000000000000000000002705 138.0
HFD1_k127_3986999_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000008012 118.0
HFD1_k127_4026041_0 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000003355 187.0
HFD1_k127_4026041_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000004981 90.0
HFD1_k127_4026041_2 periplasmic or secreted lipoprotein - - - 0.00000008619 54.0
HFD1_k127_40463_0 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 581.0
HFD1_k127_40463_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 519.0
HFD1_k127_40463_10 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 331.0
HFD1_k127_40463_11 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 306.0
HFD1_k127_40463_12 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 306.0
HFD1_k127_40463_13 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 304.0
HFD1_k127_40463_14 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 303.0
HFD1_k127_40463_15 oxidoreductase activity, acting on CH-OH group of donors K13237 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
HFD1_k127_40463_16 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001835 281.0
HFD1_k127_40463_17 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003917 270.0
HFD1_k127_40463_18 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000195 273.0
HFD1_k127_40463_19 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001757 277.0
HFD1_k127_40463_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009982 434.0
HFD1_k127_40463_20 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004468 273.0
HFD1_k127_40463_21 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002854 263.0
HFD1_k127_40463_22 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000008666 248.0
HFD1_k127_40463_23 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 242.0
HFD1_k127_40463_24 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000001772 235.0
HFD1_k127_40463_25 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000004079 230.0
HFD1_k127_40463_26 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000008204 246.0
HFD1_k127_40463_27 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000002352 219.0
HFD1_k127_40463_28 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000003604 201.0
HFD1_k127_40463_29 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000003374 191.0
HFD1_k127_40463_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 426.0
HFD1_k127_40463_30 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000009161 204.0
HFD1_k127_40463_31 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000002329 191.0
HFD1_k127_40463_32 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000005297 189.0
HFD1_k127_40463_33 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000001114 174.0
HFD1_k127_40463_34 SNARE associated Golgi protein K19302 - 3.6.1.27 0.000000000000000000000000000000000000001898 154.0
HFD1_k127_40463_35 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000009484 151.0
HFD1_k127_40463_36 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000006 153.0
HFD1_k127_40463_37 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000004193 149.0
HFD1_k127_40463_38 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000003222 134.0
HFD1_k127_40463_39 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000006905 127.0
HFD1_k127_40463_4 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 424.0
HFD1_k127_40463_40 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000001216 120.0
HFD1_k127_40463_41 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K02379,K03752,K03753,K13818 - 2.7.7.77 0.00000000000000000000000201 112.0
HFD1_k127_40463_42 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000006711 109.0
HFD1_k127_40463_43 protein localization to T-tubule K21440 - - 0.0000000000000000000001551 108.0
HFD1_k127_40463_44 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000326 96.0
HFD1_k127_40463_45 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000006485 103.0
HFD1_k127_40463_46 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000003151 94.0
HFD1_k127_40463_47 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000323 94.0
HFD1_k127_40463_48 PFAM SNARE associated Golgi protein - - - 0.0000000000000000187 90.0
HFD1_k127_40463_49 RDD family - - - 0.00000000001753 70.0
HFD1_k127_40463_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 396.0
HFD1_k127_40463_50 - - - - 0.0000000005916 70.0
HFD1_k127_40463_51 CAAX protease self-immunity K07052 - - 0.000001948 58.0
HFD1_k127_40463_52 transferase activity, transferring glycosyl groups - - - 0.000002278 57.0
HFD1_k127_40463_53 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.000008306 57.0
HFD1_k127_40463_6 RNA polymerase sigma-54 factor K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 368.0
HFD1_k127_40463_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 339.0
HFD1_k127_40463_8 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 353.0
HFD1_k127_40463_9 sh3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 327.0
HFD1_k127_4065337_0 TIGRFAM rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - 0.0 1010.0
HFD1_k127_4065337_1 Belongs to the glycosyl hydrolase 43 family - - - 7.638e-236 740.0
HFD1_k127_4065337_10 inositol monophosphate 1-phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 422.0
HFD1_k127_4065337_11 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 418.0
HFD1_k127_4065337_12 xylulokinase activity K00848,K00851,K00854 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.12,2.7.1.17,2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 417.0
HFD1_k127_4065337_13 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 390.0
HFD1_k127_4065337_14 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 368.0
HFD1_k127_4065337_15 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007922 276.0
HFD1_k127_4065337_16 TIGRFAM iron-sulfur cluster binding protein K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 248.0
HFD1_k127_4065337_17 Domain of unknown function (DUF4861) K01051 - 3.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000422 231.0
HFD1_k127_4065337_18 FCD - - - 0.000000000000000000000000000000000002094 146.0
HFD1_k127_4065337_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 4.027e-207 657.0
HFD1_k127_4065337_3 isomerase K01820 - 5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 600.0
HFD1_k127_4065337_4 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 554.0
HFD1_k127_4065337_5 transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 543.0
HFD1_k127_4065337_6 PFAM Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 512.0
HFD1_k127_4065337_7 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 493.0
HFD1_k127_4065337_8 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 485.0
HFD1_k127_4065337_9 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 445.0
HFD1_k127_4068656_0 PLD-like domain - - - 7.281e-219 692.0
HFD1_k127_4068656_1 ABC transporter transmembrane region K06147 - - 1.758e-209 673.0
HFD1_k127_4068656_10 positive regulation of growth rate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 414.0
HFD1_k127_4068656_11 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 406.0
HFD1_k127_4068656_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 373.0
HFD1_k127_4068656_13 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 388.0
HFD1_k127_4068656_14 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 353.0
HFD1_k127_4068656_15 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000001286 252.0
HFD1_k127_4068656_16 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000004935 220.0
HFD1_k127_4068656_17 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000001817 217.0
HFD1_k127_4068656_18 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000001559 218.0
HFD1_k127_4068656_2 pyrroloquinoline quinone binding K01206,K01218 - 3.2.1.51,3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 630.0
HFD1_k127_4068656_20 membrane - - - 0.000000000000000000000000000000000000000000000000001775 201.0
HFD1_k127_4068656_21 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000001432 172.0
HFD1_k127_4068656_23 - - - - 0.00000000000000000000002266 101.0
HFD1_k127_4068656_24 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000114 110.0
HFD1_k127_4068656_25 - - - - 0.00000000002902 73.0
HFD1_k127_4068656_26 GAF domain - - - 0.00000000002902 73.0
HFD1_k127_4068656_27 PFAM Uncharacterised protein family UPF0150 - - - 0.000001495 49.0
HFD1_k127_4068656_28 Protein tyrosine kinase - - - 0.00006711 46.0
HFD1_k127_4068656_29 Belongs to the peptidase S1 family K01312,K01489 - 3.4.21.4,3.5.4.5 0.0001959 47.0
HFD1_k127_4068656_3 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 605.0
HFD1_k127_4068656_30 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0004604 43.0
HFD1_k127_4068656_31 AntiSigma factor - - - 0.0009772 47.0
HFD1_k127_4068656_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 618.0
HFD1_k127_4068656_5 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 601.0
HFD1_k127_4068656_6 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 592.0
HFD1_k127_4068656_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 484.0
HFD1_k127_4068656_8 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 446.0
HFD1_k127_4068656_9 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 459.0
HFD1_k127_413346_0 Cytochrome c - - - 3.107e-305 974.0
HFD1_k127_413346_1 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 1.593e-194 625.0
HFD1_k127_413346_10 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006563 254.0
HFD1_k127_413346_11 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000003794 229.0
HFD1_k127_413346_12 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000002744 206.0
HFD1_k127_413346_13 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000104 203.0
HFD1_k127_413346_14 heme a metabolic process K02259,K03110 - - 0.000000000000000000000000000000000000000000002462 177.0
HFD1_k127_413346_15 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000002524 149.0
HFD1_k127_413346_16 30S ribosomal protein S23 - - - 0.00000000000000000000000000000001936 130.0
HFD1_k127_413346_17 Transposase IS200 like - - - 0.0000000000000000000000003325 110.0
HFD1_k127_413346_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 599.0
HFD1_k127_413346_3 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 489.0
HFD1_k127_413346_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 463.0
HFD1_k127_413346_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 418.0
HFD1_k127_413346_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 305.0
HFD1_k127_413346_7 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005905 281.0
HFD1_k127_413346_8 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007588 265.0
HFD1_k127_413346_9 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002314 265.0
HFD1_k127_4133757_0 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.0000000000000000000000000001023 129.0
HFD1_k127_4133757_1 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000005557 78.0
HFD1_k127_4133757_2 Lipopolysaccharide-assembly - - - 0.00001158 48.0
HFD1_k127_4164009_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 403.0
HFD1_k127_4164009_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 364.0
HFD1_k127_4164009_2 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
HFD1_k127_4164009_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003203 278.0
HFD1_k127_4164009_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000036 278.0
HFD1_k127_4164009_5 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000004593 273.0
HFD1_k127_4164009_6 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000253 251.0
HFD1_k127_4164009_7 - - - - 0.000000000000000000000000000000000000000000000000004271 186.0
HFD1_k127_4165_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.053e-303 951.0
HFD1_k127_4165_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 569.0
HFD1_k127_4165_10 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 312.0
HFD1_k127_4165_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 310.0
HFD1_k127_4165_12 Belongs to the BshC family K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 313.0
HFD1_k127_4165_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008263 274.0
HFD1_k127_4165_14 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003213 272.0
HFD1_k127_4165_15 Serine aminopeptidase, S33 K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003578 279.0
HFD1_k127_4165_16 Phage Tail Collar Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000702 260.0
HFD1_k127_4165_17 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000002847 262.0
HFD1_k127_4165_18 Domain of unknown function (DUF4347) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005143 288.0
HFD1_k127_4165_19 Tail Collar domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001201 252.0
HFD1_k127_4165_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 524.0
HFD1_k127_4165_20 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000001892 226.0
HFD1_k127_4165_21 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000009957 222.0
HFD1_k127_4165_22 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000002687 229.0
HFD1_k127_4165_23 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000001771 214.0
HFD1_k127_4165_24 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000002646 189.0
HFD1_k127_4165_25 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000003903 184.0
HFD1_k127_4165_26 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000002513 178.0
HFD1_k127_4165_27 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000002812 184.0
HFD1_k127_4165_28 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000005189 205.0
HFD1_k127_4165_29 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000004651 202.0
HFD1_k127_4165_3 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 501.0
HFD1_k127_4165_30 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000005575 177.0
HFD1_k127_4165_31 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000001089 167.0
HFD1_k127_4165_32 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000002165 178.0
HFD1_k127_4165_33 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.00000000000000000000000000000000000000007977 161.0
HFD1_k127_4165_34 2OG-Fe(II) oxygenase superfamily K07336,K07394 - - 0.00000000000000000000000000000000000004067 149.0
HFD1_k127_4165_35 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000004874 139.0
HFD1_k127_4165_36 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000002565 133.0
HFD1_k127_4165_37 DSBA-like thioredoxin domain K21990 - - 0.0000000000000000000000000000001702 132.0
HFD1_k127_4165_38 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000376 123.0
HFD1_k127_4165_39 PFAM Surface antigen variable number K07277 - - 0.000000000000000000000000000173 131.0
HFD1_k127_4165_4 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 464.0
HFD1_k127_4165_40 domain, Protein - - - 0.000000000000000000000000004045 114.0
HFD1_k127_4165_41 Biotin-requiring enzyme - - - 0.0000000000000000000000000196 114.0
HFD1_k127_4165_42 TPR repeat - - - 0.00000000000000000000000008868 121.0
HFD1_k127_4165_43 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000001316 106.0
HFD1_k127_4165_44 protein trimerization - - - 0.000000000000000000000002377 108.0
HFD1_k127_4165_45 cell redox homeostasis K02199 - - 0.0000000000000000000007158 104.0
HFD1_k127_4165_46 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000006709 86.0
HFD1_k127_4165_47 - - - - 0.000000000002059 73.0
HFD1_k127_4165_48 - - - - 0.0000000000317 65.0
HFD1_k127_4165_49 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000004079 67.0
HFD1_k127_4165_5 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 446.0
HFD1_k127_4165_50 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000009854 66.0
HFD1_k127_4165_51 Tetratricopeptide repeat - - - 0.000001805 59.0
HFD1_k127_4165_52 - - - - 0.000003649 57.0
HFD1_k127_4165_55 - - - - 0.00001748 50.0
HFD1_k127_4165_56 Protein of unknown function (DUF721) - - - 0.00002678 52.0
HFD1_k127_4165_57 Domain of unknown function (DUF4926) - - - 0.00005305 49.0
HFD1_k127_4165_58 - - - - 0.00005964 49.0
HFD1_k127_4165_59 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0001301 58.0
HFD1_k127_4165_6 ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 440.0
HFD1_k127_4165_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 342.0
HFD1_k127_4165_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 319.0
HFD1_k127_4165_9 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 320.0
HFD1_k127_4174971_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 367.0
HFD1_k127_4174971_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000002301 187.0
HFD1_k127_4175928_0 Tricorn protease C1 domain K08676 - - 0.0 1255.0
HFD1_k127_4175928_1 protein secretion by the type I secretion system K11085 - - 4.183e-260 814.0
HFD1_k127_4175928_10 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 400.0
HFD1_k127_4175928_11 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 388.0
HFD1_k127_4175928_12 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 377.0
HFD1_k127_4175928_13 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 304.0
HFD1_k127_4175928_14 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007199 277.0
HFD1_k127_4175928_15 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002618 285.0
HFD1_k127_4175928_16 AraC family K07506 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001605 267.0
HFD1_k127_4175928_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001029 250.0
HFD1_k127_4175928_18 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000003274 248.0
HFD1_k127_4175928_19 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000001477 248.0
HFD1_k127_4175928_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.261e-250 789.0
HFD1_k127_4175928_20 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000004192 237.0
HFD1_k127_4175928_21 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001908 233.0
HFD1_k127_4175928_22 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000000000000000002794 234.0
HFD1_k127_4175928_23 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
HFD1_k127_4175928_24 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001165 244.0
HFD1_k127_4175928_25 - - - - 0.000000000000000000000000000000000000000000000000000000000001688 213.0
HFD1_k127_4175928_26 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.00000000000000000000000000000000000000000000000000000000006201 208.0
HFD1_k127_4175928_27 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000148 233.0
HFD1_k127_4175928_28 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000001322 184.0
HFD1_k127_4175928_29 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000001677 175.0
HFD1_k127_4175928_3 COG3653 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 3.658e-215 682.0
HFD1_k127_4175928_30 DinB superfamily - - - 0.0000000000000000000000000000000000000000000198 167.0
HFD1_k127_4175928_31 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000941 149.0
HFD1_k127_4175928_32 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000001309 160.0
HFD1_k127_4175928_33 - - - - 0.000000000000000000000000000000000001691 144.0
HFD1_k127_4175928_34 Cytochrome c - - - 0.0000000000000000000000000000000008357 137.0
HFD1_k127_4175928_35 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000000000000000001987 135.0
HFD1_k127_4175928_36 Transcriptional regulator - - - 0.0000000000000000000000000000006039 125.0
HFD1_k127_4175928_37 - - - - 0.000000000000000000001912 97.0
HFD1_k127_4175928_38 TIGRFAM MoaD family protein K03636 - - 0.000000000000000216 83.0
HFD1_k127_4175928_39 transcriptional regulator, RpiR family - - - 0.0000000000000002415 90.0
HFD1_k127_4175928_4 PFAM 4Fe-4S binding domain - - - 3.866e-202 638.0
HFD1_k127_4175928_40 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000003341 55.0
HFD1_k127_4175928_41 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00001479 50.0
HFD1_k127_4175928_5 Reductase C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 596.0
HFD1_k127_4175928_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 576.0
HFD1_k127_4175928_7 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 526.0
HFD1_k127_4175928_8 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 514.0
HFD1_k127_4175928_9 smart pdz dhr glgf K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 432.0
HFD1_k127_4179828_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 1.973e-272 846.0
HFD1_k127_4179828_1 Aromatic amino acid lyase K01745 - 4.3.1.3 1.696e-198 629.0
HFD1_k127_4179828_10 Predicted integral membrane protein (DUF2270) - - - 0.000000000000000000000000000000000000000000000000000000000000004138 231.0
HFD1_k127_4179828_11 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000008523 197.0
HFD1_k127_4179828_12 - - - - 0.000000000000000000000000000000000000000000000001755 182.0
HFD1_k127_4179828_13 PIN domain - - - 0.0000000000000000000000000000000000000000000001157 172.0
HFD1_k127_4179828_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000779 162.0
HFD1_k127_4179828_15 - - - - 0.0000000000000000000000000000000000000000157 158.0
HFD1_k127_4179828_17 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000005271 151.0
HFD1_k127_4179828_18 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000002777 124.0
HFD1_k127_4179828_19 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000418 106.0
HFD1_k127_4179828_2 F5/8 type C domain - - - 6.043e-197 636.0
HFD1_k127_4179828_21 - - - - 0.000000000000001906 79.0
HFD1_k127_4179828_25 - - - - 0.000007703 57.0
HFD1_k127_4179828_3 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 599.0
HFD1_k127_4179828_4 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 459.0
HFD1_k127_4179828_5 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 409.0
HFD1_k127_4179828_6 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 410.0
HFD1_k127_4179828_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 318.0
HFD1_k127_4179828_8 Domain of unknown function (DUF4287) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002682 239.0
HFD1_k127_4179828_9 Enoyl-CoA hydratase/isomerase K01715,K13767 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000447 228.0
HFD1_k127_4210179_0 AMP-binding enzyme C-terminal domain K00666 - - 7.161e-252 785.0
HFD1_k127_4210179_1 serine threonine protein kinase K12132 - 2.7.11.1 1.433e-206 677.0
HFD1_k127_4210179_10 Belongs to the UPF0235 family K09131 - - 0.000000000000000000004853 98.0
HFD1_k127_4210179_11 YGGT family K02221 - - 0.000000000002692 75.0
HFD1_k127_4210179_2 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 330.0
HFD1_k127_4210179_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 329.0
HFD1_k127_4210179_4 isomerase activity K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000002167 218.0
HFD1_k127_4210179_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000003059 213.0
HFD1_k127_4210179_6 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000116 214.0
HFD1_k127_4210179_7 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000002403 171.0
HFD1_k127_4210179_8 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000000000002164 162.0
HFD1_k127_4210179_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000002404 164.0
HFD1_k127_4216171_0 Peptidase family M3 K01284 - 3.4.15.5 0.0 1043.0
HFD1_k127_4216171_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 405.0
HFD1_k127_4216171_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 371.0
HFD1_k127_4216171_3 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 290.0
HFD1_k127_4216171_4 - - - - 0.00000000000000000000000000000000000000000000884 173.0
HFD1_k127_4216171_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000008074 151.0
HFD1_k127_4238905_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 518.0
HFD1_k127_4238905_1 recA bacterial DNA recombination protein - - - 0.0000000000000000000000000000000000000000000000000000003055 203.0
HFD1_k127_4238905_2 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000171 160.0
HFD1_k127_4238905_3 - - - - 0.000000000000000000000000000000000000000008148 161.0
HFD1_k127_4248127_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 482.0
HFD1_k127_4248127_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000151 114.0
HFD1_k127_4254271_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.122e-222 698.0
HFD1_k127_4254271_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928 509.0
HFD1_k127_4254271_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 463.0
HFD1_k127_4254271_3 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 347.0
HFD1_k127_4254271_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000004555 89.0
HFD1_k127_4266755_0 cellulose binding - - - 0.0 1363.0
HFD1_k127_4266755_1 Prolyl oligopeptidase family - - - 1.082e-267 843.0
HFD1_k127_4266755_10 COG2931 RTX toxins and related Ca2 -binding - - - 0.000008954 52.0
HFD1_k127_4266755_11 - - - - 0.0002573 53.0
HFD1_k127_4266755_2 L-lactate permease K03303 - - 2.44e-238 749.0
HFD1_k127_4266755_3 IgA Peptidase M64 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 602.0
HFD1_k127_4266755_4 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 379.0
HFD1_k127_4266755_5 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 298.0
HFD1_k127_4266755_6 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001086 274.0
HFD1_k127_4266755_7 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000852 254.0
HFD1_k127_4266755_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000001669 154.0
HFD1_k127_4266755_9 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.00000000171 64.0
HFD1_k127_4268008_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 389.0
HFD1_k127_4268008_1 efflux transmembrane transporter activity - - - 0.0000000000000000004769 94.0
HFD1_k127_4268008_2 MacB-like periplasmic core domain - - - 0.0000000000000000157 85.0
HFD1_k127_4268008_3 efflux transmembrane transporter activity K02004 - - 0.000001872 49.0
HFD1_k127_4316003_0 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 453.0
HFD1_k127_4316003_1 RNA recognition motif - - - 0.0000000000000000000000000000000000000000000191 164.0
HFD1_k127_4368874_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1422.0
HFD1_k127_4368874_1 Penicillin amidase K07116 - 3.5.1.97 2.971e-227 729.0
HFD1_k127_4368874_10 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000002289 155.0
HFD1_k127_4368874_11 - - - - 0.0000000000000000000000000000000001883 135.0
HFD1_k127_4368874_12 InterPro IPR007367 - - - 0.00000000000000000000000000001094 119.0
HFD1_k127_4368874_13 response to heat K03668,K09914 - - 0.00000000000000000001196 98.0
HFD1_k127_4368874_14 - - - - 0.000000006864 63.0
HFD1_k127_4368874_2 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 482.0
HFD1_k127_4368874_3 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 447.0
HFD1_k127_4368874_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001267 273.0
HFD1_k127_4368874_5 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000001071 218.0
HFD1_k127_4368874_6 DinB family - - - 0.00000000000000000000000000000000000000000000001312 178.0
HFD1_k127_4368874_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.00000000000000000000000000000000000000000008672 169.0
HFD1_k127_4368874_8 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000007011 151.0
HFD1_k127_4368874_9 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000006699 156.0
HFD1_k127_4387274_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 3.07e-243 764.0
HFD1_k127_4387274_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.845e-217 685.0
HFD1_k127_4387274_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 515.0
HFD1_k127_4387274_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 417.0
HFD1_k127_4387274_4 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000001356 219.0
HFD1_k127_4387274_5 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000193 186.0
HFD1_k127_4387274_6 ABC 3 transport family K02015 - - 0.00000000000000000000000000000000000001062 157.0
HFD1_k127_4387274_7 DinB superfamily - - - 0.0000000000000000000000000007611 119.0
HFD1_k127_4438072_0 Sodium/hydrogen exchanger family - - - 1.665e-208 673.0
HFD1_k127_4438072_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000009163 161.0
HFD1_k127_4438072_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001365 155.0
HFD1_k127_4438072_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000003056 126.0
HFD1_k127_4438072_13 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000147 98.0
HFD1_k127_4438072_14 KH domain K06960 - - 0.000000000000000003832 87.0
HFD1_k127_4438072_15 Glucose Sorbosone dehydrogenase - - - 0.0000000000000002712 95.0
HFD1_k127_4438072_16 serine threonine protein kinase - - - 0.0000000000001994 72.0
HFD1_k127_4438072_17 zinc-ribbon domain - - - 0.000000000003171 76.0
HFD1_k127_4438072_18 PFAM Fimbrial assembly family protein K02663 - - 0.000000001545 66.0
HFD1_k127_4438072_19 Type II secretory pathway, pseudopilin - - - 0.00000008511 62.0
HFD1_k127_4438072_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 496.0
HFD1_k127_4438072_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 420.0
HFD1_k127_4438072_4 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 380.0
HFD1_k127_4438072_5 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 284.0
HFD1_k127_4438072_6 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004798 287.0
HFD1_k127_4438072_7 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004647 287.0
HFD1_k127_4438072_8 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000001173 195.0
HFD1_k127_4438072_9 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000002571 166.0
HFD1_k127_4598910_0 Carboxypeptidase regulatory-like domain - - - 7.559e-267 862.0
HFD1_k127_4598910_1 ABC transporter transmembrane region K11085 - - 9.372e-243 764.0
HFD1_k127_4598910_10 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 532.0
HFD1_k127_4598910_11 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 520.0
HFD1_k127_4598910_12 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 482.0
HFD1_k127_4598910_13 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 469.0
HFD1_k127_4598910_14 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 423.0
HFD1_k127_4598910_15 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 406.0
HFD1_k127_4598910_16 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 403.0
HFD1_k127_4598910_17 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 381.0
HFD1_k127_4598910_18 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 368.0
HFD1_k127_4598910_19 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 344.0
HFD1_k127_4598910_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 6.87e-203 653.0
HFD1_k127_4598910_20 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 317.0
HFD1_k127_4598910_21 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 319.0
HFD1_k127_4598910_22 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 336.0
HFD1_k127_4598910_23 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 291.0
HFD1_k127_4598910_24 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004096 286.0
HFD1_k127_4598910_25 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000929 287.0
HFD1_k127_4598910_26 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003374 284.0
HFD1_k127_4598910_27 membrane protein, hemolysin III homolog K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004576 268.0
HFD1_k127_4598910_28 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008414 252.0
HFD1_k127_4598910_29 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000002184 234.0
HFD1_k127_4598910_3 Ribosomal protein S1 K02945 - - 8.227e-197 631.0
HFD1_k127_4598910_30 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000007171 233.0
HFD1_k127_4598910_31 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000000005502 224.0
HFD1_k127_4598910_32 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000008544 226.0
HFD1_k127_4598910_33 - - - - 0.000000000000000000000000000000000000000000000000000000000008231 221.0
HFD1_k127_4598910_34 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000004494 214.0
HFD1_k127_4598910_35 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000001234 196.0
HFD1_k127_4598910_36 NDK K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000195 185.0
HFD1_k127_4598910_37 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000379 188.0
HFD1_k127_4598910_38 Membrane - - - 0.0000000000000000000000000000000000000000000001431 192.0
HFD1_k127_4598910_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000003031 172.0
HFD1_k127_4598910_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 600.0
HFD1_k127_4598910_40 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000004847 178.0
HFD1_k127_4598910_41 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.000000000000000000000000000000000000000000005159 166.0
HFD1_k127_4598910_42 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000003269 172.0
HFD1_k127_4598910_43 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.000000000000000000000000000000000000001736 156.0
HFD1_k127_4598910_44 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000007104 154.0
HFD1_k127_4598910_45 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000000000000000000000000000003374 146.0
HFD1_k127_4598910_46 protein conserved in bacteria - - - 0.0000000000000000000000000000000001233 138.0
HFD1_k127_4598910_47 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000003145 152.0
HFD1_k127_4598910_48 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000003811 139.0
HFD1_k127_4598910_49 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000485 139.0
HFD1_k127_4598910_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 577.0
HFD1_k127_4598910_50 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000000001446 127.0
HFD1_k127_4598910_51 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000001276 130.0
HFD1_k127_4598910_52 Alternative locus ID - - - 0.000000000000000000000000000003829 134.0
HFD1_k127_4598910_53 regulation of translation K05788 - - 0.000000000000000000000000000008252 120.0
HFD1_k127_4598910_54 peptidase inhibitor activity - - - 0.000000000000000000000000008085 122.0
HFD1_k127_4598910_55 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000007732 105.0
HFD1_k127_4598910_56 peptidase inhibitor activity - - - 0.000000000000000000000002727 112.0
HFD1_k127_4598910_57 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000003336 116.0
HFD1_k127_4598910_58 Pfam:DUF1311 - - - 0.00000000000000000000003683 103.0
HFD1_k127_4598910_59 VWA domain containing CoxE-like protein - - - 0.0000000000000000000001821 110.0
HFD1_k127_4598910_6 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 581.0
HFD1_k127_4598910_60 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000002307 100.0
HFD1_k127_4598910_61 Transglutaminase-like superfamily - - - 0.00000000000000000000121 113.0
HFD1_k127_4598910_62 von Willebrand factor, type A - - - 0.00000000000000009487 93.0
HFD1_k127_4598910_63 YCII-related domain K09780 - - 0.0000000000000001529 83.0
HFD1_k127_4598910_64 von Willebrand factor, type A K07114,K12511 - - 0.0000000000000006699 89.0
HFD1_k127_4598910_65 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000002729 87.0
HFD1_k127_4598910_66 - - - - 0.0000000000004797 76.0
HFD1_k127_4598910_67 snoRNA binding - - - 0.0000000006915 65.0
HFD1_k127_4598910_68 TPR repeat - - - 0.0000000007785 71.0
HFD1_k127_4598910_7 silver ion transport K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 582.0
HFD1_k127_4598910_70 protein tyrosine phosphatase activity K18045 GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006897,GO:0006996,GO:0007010,GO:0007015,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016192,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0023052,GO:0030029,GO:0030036,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0071704,GO:0071840,GO:0097435,GO:0098657,GO:0140096,GO:1901564 3.1.3.48 0.00000001159 64.0
HFD1_k127_4598910_71 histone H2A K63-linked ubiquitination - - - 0.00000001663 63.0
HFD1_k127_4598910_72 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00006766 51.0
HFD1_k127_4598910_74 23S rRNA-intervening sequence protein - - - 0.000173 47.0
HFD1_k127_4598910_76 COG0457 FOG TPR repeat - - - 0.0004119 55.0
HFD1_k127_4598910_77 23S rRNA-intervening sequence protein - - - 0.0008195 42.0
HFD1_k127_4598910_78 IPT TIG domain - - - 0.0008503 49.0
HFD1_k127_4598910_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 540.0
HFD1_k127_4598910_9 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 542.0
HFD1_k127_4610427_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 593.0
HFD1_k127_4610427_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000001199 123.0
HFD1_k127_4682673_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1068.0
HFD1_k127_4682673_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 501.0
HFD1_k127_4682673_10 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000006166 163.0
HFD1_k127_4682673_11 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000003829 135.0
HFD1_k127_4682673_12 - - - - 0.000000000000000000000000000002275 134.0
HFD1_k127_4682673_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000012 121.0
HFD1_k127_4682673_14 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000007709 123.0
HFD1_k127_4682673_15 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000001097 74.0
HFD1_k127_4682673_16 Transposase - - - 0.000000001594 59.0
HFD1_k127_4682673_17 - - - - 0.00000005622 55.0
HFD1_k127_4682673_18 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000001812 54.0
HFD1_k127_4682673_19 TPR repeat - - - 0.000002771 59.0
HFD1_k127_4682673_2 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 492.0
HFD1_k127_4682673_20 - - - - 0.000003721 52.0
HFD1_k127_4682673_3 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 422.0
HFD1_k127_4682673_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 383.0
HFD1_k127_4682673_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 363.0
HFD1_k127_4682673_6 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 348.0
HFD1_k127_4682673_7 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 308.0
HFD1_k127_4682673_8 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001507 281.0
HFD1_k127_4682673_9 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001686 281.0
HFD1_k127_4689151_0 PFAM ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 453.0
HFD1_k127_4689151_1 peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000007405 136.0
HFD1_k127_4689151_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000003519 97.0
HFD1_k127_4701148_0 Carboxypeptidase regulatory-like domain - - - 9.922e-241 781.0
HFD1_k127_4701148_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 499.0
HFD1_k127_4701148_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000126 249.0
HFD1_k127_4701148_11 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000002083 235.0
HFD1_k127_4701148_12 domain protein K02238 - - 0.00000000000000000000000000000000000000000000000006081 193.0
HFD1_k127_4701148_13 RDD family - - - 0.00000000000000000000000000000000000000000002368 173.0
HFD1_k127_4701148_14 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.00000000000000000000000000000000000000007271 156.0
HFD1_k127_4701148_15 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000002844 110.0
HFD1_k127_4701148_16 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000001987 108.0
HFD1_k127_4701148_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000001156 84.0
HFD1_k127_4701148_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 462.0
HFD1_k127_4701148_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 407.0
HFD1_k127_4701148_4 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 405.0
HFD1_k127_4701148_5 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 398.0
HFD1_k127_4701148_6 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 350.0
HFD1_k127_4701148_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 336.0
HFD1_k127_4701148_8 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 318.0
HFD1_k127_4701148_9 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 294.0
HFD1_k127_470218_0 AcrB/AcrD/AcrF family - - - 1.026e-225 714.0
HFD1_k127_470218_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 512.0
HFD1_k127_470218_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 315.0
HFD1_k127_470218_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000001877 226.0
HFD1_k127_470218_4 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000007222 215.0
HFD1_k127_470218_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000001395 159.0
HFD1_k127_470218_6 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000000003731 124.0
HFD1_k127_470218_7 Protein of unknown function (DUF2892) - - - 0.00000000000000000003906 91.0
HFD1_k127_483753_0 Flavin-binding monooxygenase-like K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 542.0
HFD1_k127_483753_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 518.0
HFD1_k127_483753_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 432.0
HFD1_k127_483753_3 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.00000000000000000000000000000000000000000000000000000001384 207.0
HFD1_k127_483753_4 Scaffold protein Nfu/NifU N terminal - - - 0.00000000000000000000000000000000000000000000000006734 183.0
HFD1_k127_483753_5 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000004658 126.0
HFD1_k127_483753_6 - - - - 0.0000000001465 71.0
HFD1_k127_483753_7 Putative adhesin - - - 0.0000001707 62.0
HFD1_k127_4837840_0 - - - - 0.0 1011.0
HFD1_k127_4837840_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 8.415e-305 948.0
HFD1_k127_4837840_10 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 405.0
HFD1_k127_4837840_11 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 363.0
HFD1_k127_4837840_12 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 338.0
HFD1_k127_4837840_13 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 316.0
HFD1_k127_4837840_14 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 318.0
HFD1_k127_4837840_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 304.0
HFD1_k127_4837840_16 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 295.0
HFD1_k127_4837840_17 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 295.0
HFD1_k127_4837840_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000279 292.0
HFD1_k127_4837840_19 oxidoreductase activity K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 294.0
HFD1_k127_4837840_2 PFAM NAD-dependent epimerase dehydratase - - - 1.797e-221 695.0
HFD1_k127_4837840_20 ethanolamine catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009689 258.0
HFD1_k127_4837840_22 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000006062 203.0
HFD1_k127_4837840_23 - - - - 0.00000000000000000000000000000000000000000000000000001553 196.0
HFD1_k127_4837840_24 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000007986 181.0
HFD1_k127_4837840_25 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000000000000000000000002911 164.0
HFD1_k127_4837840_26 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000000000000000000000000000000000000003914 159.0
HFD1_k127_4837840_27 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000001559 153.0
HFD1_k127_4837840_28 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000001484 154.0
HFD1_k127_4837840_29 BMC - - - 0.0000000000000000000000000000000000001437 145.0
HFD1_k127_4837840_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.143e-204 644.0
HFD1_k127_4837840_30 Redoxin - - - 0.0000000000000000000000000000000000002542 142.0
HFD1_k127_4837840_31 Y_Y_Y domain - - - 0.00000000000000000000000000000004005 147.0
HFD1_k127_4837840_32 BMC - - - 0.0000000000000000000000000000007303 124.0
HFD1_k127_4837840_33 - - - - 0.00000000000000000000000000000472 124.0
HFD1_k127_4837840_34 glyoxalase III activity - - - 0.0000000000000000000000000001449 122.0
HFD1_k127_4837840_35 Transcriptional regulator C-terminal region - - - 0.0000000000000000000000000004278 122.0
HFD1_k127_4837840_36 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000000000006437 117.0
HFD1_k127_4837840_37 Ferric uptake regulator family K09825 - - 0.00000000000000000000004906 102.0
HFD1_k127_4837840_38 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000004727 98.0
HFD1_k127_4837840_39 Belongs to the 'phage' integrase family - - - 0.000000000000000000005351 93.0
HFD1_k127_4837840_4 PFAM peptidase - - - 2.503e-201 641.0
HFD1_k127_4837840_40 Belongs to the UPF0237 family K07166 - - 0.00000000000000000002669 97.0
HFD1_k127_4837840_41 TIGRFAM DNA binding domain protein, excisionase family K22491 - - 0.0000000000000000005128 97.0
HFD1_k127_4837840_42 DNA-binding transcription factor activity - - - 0.00000000000000001362 88.0
HFD1_k127_4837840_43 aspartic-type endopeptidase activity K06399 - 3.4.21.116 0.00000000000000001428 93.0
HFD1_k127_4837840_44 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000162 82.0
HFD1_k127_4837840_45 - - - - 0.000000000000002711 80.0
HFD1_k127_4837840_46 Helix-turn-helix domain K15539 - - 0.00000000000003498 79.0
HFD1_k127_4837840_47 AhpC/TSA family - - - 0.000000000631 64.0
HFD1_k127_4837840_48 - - - - 0.0000002837 63.0
HFD1_k127_4837840_49 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000001017 58.0
HFD1_k127_4837840_5 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 578.0
HFD1_k127_4837840_50 - - - - 0.000002003 55.0
HFD1_k127_4837840_6 electron transfer activity K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 500.0
HFD1_k127_4837840_7 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 453.0
HFD1_k127_4837840_8 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 468.0
HFD1_k127_4837840_9 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 368.0
HFD1_k127_4838217_0 TIGRFAM ATP-dependent DNA helicase, RecQ family K03654 - 3.6.4.12 9.889e-268 837.0
HFD1_k127_4838217_1 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 9.096e-266 831.0
HFD1_k127_4838217_10 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 455.0
HFD1_k127_4838217_11 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 395.0
HFD1_k127_4838217_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 377.0
HFD1_k127_4838217_13 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 330.0
HFD1_k127_4838217_14 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 318.0
HFD1_k127_4838217_15 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003069 283.0
HFD1_k127_4838217_16 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000646 273.0
HFD1_k127_4838217_17 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.00000000000000000000000000000000000000000000000000000000000000000003268 246.0
HFD1_k127_4838217_18 Agenet domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001926 236.0
HFD1_k127_4838217_19 - - - - 0.000000000000000000000000000000000000000000000000000000000002925 214.0
HFD1_k127_4838217_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 3.001e-252 801.0
HFD1_k127_4838217_20 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000001101 205.0
HFD1_k127_4838217_21 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000003355 205.0
HFD1_k127_4838217_22 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000006589 199.0
HFD1_k127_4838217_23 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K06878 - - 0.0000000000000000000000000000000000000000000001157 173.0
HFD1_k127_4838217_24 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000002979 171.0
HFD1_k127_4838217_25 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000001177 166.0
HFD1_k127_4838217_26 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000002441 179.0
HFD1_k127_4838217_27 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000006068 134.0
HFD1_k127_4838217_28 - - - - 0.00000000000000000000000000003906 124.0
HFD1_k127_4838217_29 transcription regulator containing HTH domain K18831 - - 0.000000000000000000000000007894 110.0
HFD1_k127_4838217_3 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3e-218 696.0
HFD1_k127_4838217_30 cheY-homologous receiver domain - - - 0.00000000000000000000000001412 113.0
HFD1_k127_4838217_31 PFAM YcfA-like protein - - - 0.0000000000000000000000001178 108.0
HFD1_k127_4838217_32 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000953 101.0
HFD1_k127_4838217_33 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000002804 93.0
HFD1_k127_4838217_34 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000003477 78.0
HFD1_k127_4838217_35 histidine kinase HAMP region domain protein K11527 - 2.7.13.3 0.00000000004846 66.0
HFD1_k127_4838217_36 HAMP domain K02482 - 2.7.13.3 0.00002252 55.0
HFD1_k127_4838217_37 Homodimerisation domain of SGTA K16365 GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006620,GO:0006810,GO:0006886,GO:0006950,GO:0008104,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0015031,GO:0015833,GO:0016192,GO:0032947,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0072379,GO:0072380,GO:0072594,GO:0072599,GO:0072657,GO:0090150 - 0.0001372 54.0
HFD1_k127_4838217_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.104e-217 690.0
HFD1_k127_4838217_5 HELICc2 K03722 - 3.6.4.12 2.275e-202 649.0
HFD1_k127_4838217_6 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 568.0
HFD1_k127_4838217_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 567.0
HFD1_k127_4838217_8 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 565.0
HFD1_k127_4838217_9 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 505.0
HFD1_k127_4838440_0 TonB-dependent receptor - - - 0.0 1085.0
HFD1_k127_4838440_1 Carboxypeptidase regulatory-like domain - - - 2.333e-302 968.0
HFD1_k127_4838440_2 alpha-L-rhamnosidase - - - 3.571e-286 909.0
HFD1_k127_4838440_3 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 1.279e-263 832.0
HFD1_k127_4838440_4 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 5.406e-201 641.0
HFD1_k127_4838440_5 Glycosyl Hydrolase Family 88 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 422.0
HFD1_k127_4848464_0 Phosphate acyltransferases K01897 - 6.2.1.3 4.07e-251 800.0
HFD1_k127_4848464_1 Protein of unknown function, DUF255 K06888 - - 3.807e-244 771.0
HFD1_k127_4848464_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 426.0
HFD1_k127_4848464_11 Belongs to the ABC transporter superfamily K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 409.0
HFD1_k127_4848464_12 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 421.0
HFD1_k127_4848464_13 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 421.0
HFD1_k127_4848464_14 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 398.0
HFD1_k127_4848464_15 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 394.0
HFD1_k127_4848464_16 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 376.0
HFD1_k127_4848464_17 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 367.0
HFD1_k127_4848464_18 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 355.0
HFD1_k127_4848464_19 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 355.0
HFD1_k127_4848464_2 Prolyl oligopeptidase family - - - 2.268e-198 639.0
HFD1_k127_4848464_20 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 343.0
HFD1_k127_4848464_21 PFAM Binding-protein-dependent transport system inner membrane component K02033,K15581,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 314.0
HFD1_k127_4848464_22 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 330.0
HFD1_k127_4848464_23 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001344 267.0
HFD1_k127_4848464_24 cell shape determining protein, MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003783 263.0
HFD1_k127_4848464_25 Methyltransferase domain K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000008161 250.0
HFD1_k127_4848464_26 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000002632 243.0
HFD1_k127_4848464_27 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000004708 243.0
HFD1_k127_4848464_28 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009422 249.0
HFD1_k127_4848464_29 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000002223 229.0
HFD1_k127_4848464_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.323e-196 635.0
HFD1_k127_4848464_30 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000189 237.0
HFD1_k127_4848464_31 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001043 217.0
HFD1_k127_4848464_33 HD domain - - - 0.00000000000000000000000000000000000000000000000000000004116 213.0
HFD1_k127_4848464_34 response regulator receiver K02483,K07658 - - 0.000000000000000000000000000000000000000000000000000001043 202.0
HFD1_k127_4848464_35 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000004022 207.0
HFD1_k127_4848464_36 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000004622 196.0
HFD1_k127_4848464_37 - - - - 0.00000000000000000000000000000000000000000000000002714 188.0
HFD1_k127_4848464_38 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.00000000000000000000000000000000000000000000000008609 181.0
HFD1_k127_4848464_39 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000002878 177.0
HFD1_k127_4848464_4 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 617.0
HFD1_k127_4848464_40 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.00000000000000000000000000000000000000000000009299 180.0
HFD1_k127_4848464_41 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000116 177.0
HFD1_k127_4848464_42 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000003958 167.0
HFD1_k127_4848464_43 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000004808 176.0
HFD1_k127_4848464_44 Penicillin-binding Protein K05364 - - 0.00000000000000000000000000000000000000005099 172.0
HFD1_k127_4848464_45 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000002775 165.0
HFD1_k127_4848464_46 EamA-like transporter family - - - 0.000000000000000000000000000000000000004336 158.0
HFD1_k127_4848464_47 L-threonylcarbamoyladenylate synthase K07566 - 2.7.7.87 0.00000000000000000000000000000000000009505 149.0
HFD1_k127_4848464_48 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000104 148.0
HFD1_k127_4848464_49 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.0000000000000000000000000000000000008161 158.0
HFD1_k127_4848464_5 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 465.0
HFD1_k127_4848464_50 - - - - 0.000000000000000000000000000000000003763 141.0
HFD1_k127_4848464_51 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000001977 137.0
HFD1_k127_4848464_52 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000001357 123.0
HFD1_k127_4848464_53 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000003319 109.0
HFD1_k127_4848464_54 - - - - 0.000000000000000000001623 102.0
HFD1_k127_4848464_55 Polymer-forming cytoskeletal - - - 0.0000000000000006547 83.0
HFD1_k127_4848464_56 23S rRNA-intervening sequence protein - - - 0.000000000000001424 77.0
HFD1_k127_4848464_57 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000001871 87.0
HFD1_k127_4848464_58 antisigma factor binding - - - 0.00000000000007417 77.0
HFD1_k127_4848464_59 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000009172 66.0
HFD1_k127_4848464_6 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 472.0
HFD1_k127_4848464_60 nuclear chromosome segregation - - - 0.0000000002719 68.0
HFD1_k127_4848464_61 Tetratricopeptide repeat - - - 0.000000002999 68.0
HFD1_k127_4848464_62 Forkhead associated domain - - - 0.000000004675 66.0
HFD1_k127_4848464_63 Endonuclease Exonuclease Phosphatase - - - 0.00000265 59.0
HFD1_k127_4848464_65 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000006736 51.0
HFD1_k127_4848464_66 - - - - 0.00001723 51.0
HFD1_k127_4848464_67 Transposase - - - 0.00002199 52.0
HFD1_k127_4848464_7 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 450.0
HFD1_k127_4848464_8 ATPases associated with a variety of cellular activities K10823,K10824 - 3.6.3.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 442.0
HFD1_k127_4848464_9 nitric oxide reductase activity K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 429.0
HFD1_k127_4862821_0 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000003482 244.0
HFD1_k127_4862821_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000008555 194.0
HFD1_k127_4862821_2 Transport permease protein K01992 - - 0.0000000000000000000000000000008809 128.0
HFD1_k127_4862821_3 Nuclease (SNase domain protein) - - - 0.00000000000000001202 95.0
HFD1_k127_4862821_4 Roadblock/LC7 domain - - - 0.0000000000000001529 83.0
HFD1_k127_4862821_5 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000001726 75.0
HFD1_k127_4862821_6 PFAM Pilus assembly protein PilO K02664 - - 0.000003366 57.0
HFD1_k127_4888145_0 Sortilin, neurotensin receptor 3, - - - 0.0 1384.0
HFD1_k127_4888145_1 copper-translocating P-type ATPase K17686 - 3.6.3.54 3.83e-313 979.0
HFD1_k127_4888145_10 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 506.0
HFD1_k127_4888145_101 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07668 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00002748 51.0
HFD1_k127_4888145_11 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 483.0
HFD1_k127_4888145_12 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 482.0
HFD1_k127_4888145_13 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 519.0
HFD1_k127_4888145_14 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 503.0
HFD1_k127_4888145_15 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 457.0
HFD1_k127_4888145_16 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 431.0
HFD1_k127_4888145_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 418.0
HFD1_k127_4888145_18 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 415.0
HFD1_k127_4888145_19 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 402.0
HFD1_k127_4888145_2 Beta-lactamase class C - - - 1.719e-244 769.0
HFD1_k127_4888145_20 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 390.0
HFD1_k127_4888145_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 409.0
HFD1_k127_4888145_22 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 351.0
HFD1_k127_4888145_23 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 344.0
HFD1_k127_4888145_24 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 342.0
HFD1_k127_4888145_25 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 346.0
HFD1_k127_4888145_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 343.0
HFD1_k127_4888145_27 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 327.0
HFD1_k127_4888145_28 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 336.0
HFD1_k127_4888145_29 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 312.0
HFD1_k127_4888145_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.157e-204 649.0
HFD1_k127_4888145_30 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 319.0
HFD1_k127_4888145_31 Proprotein convertase P-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 325.0
HFD1_k127_4888145_32 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003045 286.0
HFD1_k127_4888145_33 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008014 312.0
HFD1_k127_4888145_34 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 289.0
HFD1_k127_4888145_35 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 283.0
HFD1_k127_4888145_36 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001314 257.0
HFD1_k127_4888145_37 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000009671 248.0
HFD1_k127_4888145_38 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001778 248.0
HFD1_k127_4888145_39 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000477 231.0
HFD1_k127_4888145_4 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 622.0
HFD1_k127_4888145_40 - - - - 0.000000000000000000000000000000000000000000000000000000000000008788 224.0
HFD1_k127_4888145_41 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000001263 228.0
HFD1_k127_4888145_42 - - - - 0.000000000000000000000000000000000000000000000000000000000002199 215.0
HFD1_k127_4888145_43 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000003882 210.0
HFD1_k127_4888145_44 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000004485 220.0
HFD1_k127_4888145_45 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000863 217.0
HFD1_k127_4888145_46 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.0000000000000000000000000000000000000000000000000000002432 205.0
HFD1_k127_4888145_47 FR47-like protein K03829 - - 0.00000000000000000000000000000000000000000000000000001015 194.0
HFD1_k127_4888145_48 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000003379 195.0
HFD1_k127_4888145_49 Histidine kinase K07777,K19661,K21405 - 2.7.13.3 0.000000000000000000000000000000000000000000000002442 188.0
HFD1_k127_4888145_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 571.0
HFD1_k127_4888145_50 Belongs to the peptidase S8 family K01361,K08652 - 3.4.21.110,3.4.21.96 0.000000000000000000000000000000000000000000003729 190.0
HFD1_k127_4888145_51 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002867 168.0
HFD1_k127_4888145_52 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000004093 161.0
HFD1_k127_4888145_53 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000005172 171.0
HFD1_k127_4888145_54 - - - - 0.000000000000000000000000000000000000000001431 168.0
HFD1_k127_4888145_55 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000001982 162.0
HFD1_k127_4888145_56 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000003178 171.0
HFD1_k127_4888145_57 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000002883 158.0
HFD1_k127_4888145_58 - - - - 0.00000000000000000000000000000000000000004818 156.0
HFD1_k127_4888145_59 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000002785 161.0
HFD1_k127_4888145_6 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 563.0
HFD1_k127_4888145_60 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.00000000000000000000000000000000000001455 158.0
HFD1_k127_4888145_61 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000002711 148.0
HFD1_k127_4888145_62 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000001545 147.0
HFD1_k127_4888145_63 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000003086 149.0
HFD1_k127_4888145_64 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000003412 124.0
HFD1_k127_4888145_65 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.000000000000000000000000000008112 134.0
HFD1_k127_4888145_66 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000000012 121.0
HFD1_k127_4888145_67 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000001395 118.0
HFD1_k127_4888145_68 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000000003042 120.0
HFD1_k127_4888145_69 Belongs to the ompA family - - - 0.000000000000000000000000009165 122.0
HFD1_k127_4888145_7 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 563.0
HFD1_k127_4888145_70 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000014 115.0
HFD1_k127_4888145_71 TPM domain K06872 - - 0.00000000000000000000000001589 121.0
HFD1_k127_4888145_72 addiction module antidote protein HigA K21498 - - 0.000000000000000000000000204 109.0
HFD1_k127_4888145_73 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000004153 111.0
HFD1_k127_4888145_74 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000004304 114.0
HFD1_k127_4888145_75 PFAM WD40 domain protein beta Propeller - - - 0.000000000000000000000001343 123.0
HFD1_k127_4888145_76 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000001923 113.0
HFD1_k127_4888145_77 - - - - 0.000000000000000000001022 97.0
HFD1_k127_4888145_78 FR47-like protein - - - 0.0000000000000000001673 95.0
HFD1_k127_4888145_79 Pfam:N_methyl_2 - - - 0.0000000000000000004868 94.0
HFD1_k127_4888145_8 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 526.0
HFD1_k127_4888145_80 Pfam:N_methyl_2 - - - 0.0000000000000000007152 94.0
HFD1_k127_4888145_81 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000001232 89.0
HFD1_k127_4888145_82 Glucose Sorbosone dehydrogenase - - - 0.00000000000000001172 100.0
HFD1_k127_4888145_83 - - - - 0.00000000000000006158 86.0
HFD1_k127_4888145_84 gag-polyprotein putative aspartyl protease - - - 0.0000000000000006094 83.0
HFD1_k127_4888145_85 amine dehydrogenase activity K03496,K05592 - 3.6.4.13 0.000000000000001247 93.0
HFD1_k127_4888145_86 - - - - 0.000000000000004601 81.0
HFD1_k127_4888145_87 PFAM Methyltransferase type 12 - - - 0.00000000000001212 84.0
HFD1_k127_4888145_88 -acetyltransferase - - - 0.00000000000003314 79.0
HFD1_k127_4888145_9 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 504.0
HFD1_k127_4888145_90 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000001856 79.0
HFD1_k127_4888145_91 Psort location CytoplasmicMembrane, score - - - 0.00000000003832 76.0
HFD1_k127_4888145_92 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000005564 78.0
HFD1_k127_4888145_93 - - - - 0.0000000002549 66.0
HFD1_k127_4888145_94 carboxylic ester hydrolase activity - - - 0.0000000007819 62.0
HFD1_k127_4888145_95 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000003511 60.0
HFD1_k127_4888145_96 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000003827 59.0
HFD1_k127_4888145_97 Glucose sorbosone - - - 0.00000004347 68.0
HFD1_k127_4888145_98 Plasmid maintenance system killer K07334 - - 0.0000000857 53.0
HFD1_k127_4888145_99 PKD domain - - - 0.0000002264 65.0
HFD1_k127_4908220_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.209e-247 772.0
HFD1_k127_4908220_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.335e-209 660.0
HFD1_k127_4908220_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001032 281.0
HFD1_k127_4908220_11 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001211 299.0
HFD1_k127_4908220_12 abc transporter atp-binding protein K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002293 283.0
HFD1_k127_4908220_13 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003109 254.0
HFD1_k127_4908220_14 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006317 260.0
HFD1_k127_4908220_15 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000004994 257.0
HFD1_k127_4908220_16 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000002205 243.0
HFD1_k127_4908220_18 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000001216 195.0
HFD1_k127_4908220_19 Methyltransferase FkbM - - - 0.0000000000000000000000000000000000000000000001638 179.0
HFD1_k127_4908220_2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.824e-201 634.0
HFD1_k127_4908220_20 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000001408 175.0
HFD1_k127_4908220_21 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000002032 159.0
HFD1_k127_4908220_22 Methyltransferase domain - - - 0.00000000000000000000000000000000000006843 151.0
HFD1_k127_4908220_23 - - - - 0.000000000000000000000000000000000001876 156.0
HFD1_k127_4908220_24 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000004063 147.0
HFD1_k127_4908220_25 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000006767 149.0
HFD1_k127_4908220_26 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000004945 150.0
HFD1_k127_4908220_27 transferase activity, transferring glycosyl groups K16698 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000001417 130.0
HFD1_k127_4908220_28 AMP binding K06149 - - 0.00000000000000000000000000001732 123.0
HFD1_k127_4908220_29 O-Antigen ligase K02847 - - 0.000000000000000000000000000102 132.0
HFD1_k127_4908220_3 PFAM Carbamoyltransferase K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 608.0
HFD1_k127_4908220_30 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000001353 124.0
HFD1_k127_4908220_31 Fibronectin type 3 domain - - - 0.000000000000000000000003751 115.0
HFD1_k127_4908220_32 - - - - 0.0000000000000000000000168 108.0
HFD1_k127_4908220_33 Pfam Methyltransferase - - - 0.00000000000000000004792 98.0
HFD1_k127_4908220_34 - - - - 0.0000000000000000001878 93.0
HFD1_k127_4908220_35 Belongs to the UPF0374 family K07586 - - 0.000000000000000003943 90.0
HFD1_k127_4908220_36 Glycosyl transferases group 1 - - - 0.0000000000000002078 91.0
HFD1_k127_4908220_37 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000003342 76.0
HFD1_k127_4908220_38 Domain of unknown function (DUF4136) - - - 0.000000002714 66.0
HFD1_k127_4908220_39 glycosyl transferase group 1 - - - 0.000000006373 68.0
HFD1_k127_4908220_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 550.0
HFD1_k127_4908220_40 luxR family - - - 0.00000001044 65.0
HFD1_k127_4908220_41 O-methyltransferase activity - - - 0.0000001057 63.0
HFD1_k127_4908220_42 Polysaccharide biosynthesis protein - - - 0.000005351 59.0
HFD1_k127_4908220_43 - - - - 0.00005452 56.0
HFD1_k127_4908220_44 - - - - 0.0001425 47.0
HFD1_k127_4908220_45 Uncharacterised nucleotidyltransferase - - - 0.0003327 52.0
HFD1_k127_4908220_46 Peroxisomal targeting signal 1 receptor K13342 - - 0.0005457 52.0
HFD1_k127_4908220_5 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 414.0
HFD1_k127_4908220_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 353.0
HFD1_k127_4908220_7 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 326.0
HFD1_k127_4908220_8 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 346.0
HFD1_k127_4908220_9 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 290.0
HFD1_k127_4916996_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 589.0
HFD1_k127_4916996_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 463.0
HFD1_k127_4916996_10 ribose 5-phosphate isomerase B K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000000003132 162.0
HFD1_k127_4916996_11 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000009929 139.0
HFD1_k127_4916996_12 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000007082 130.0
HFD1_k127_4916996_13 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000693 120.0
HFD1_k127_4916996_14 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000001106 121.0
HFD1_k127_4916996_15 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000005862 126.0
HFD1_k127_4916996_16 von Willebrand factor, type A - - - 0.00000000000000000004123 104.0
HFD1_k127_4916996_17 nucleotide catabolic process K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.0000000000000000008805 96.0
HFD1_k127_4916996_18 - - - - 0.0000001214 55.0
HFD1_k127_4916996_19 - - - - 0.0000001856 60.0
HFD1_k127_4916996_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 415.0
HFD1_k127_4916996_20 Cytochrome c K12263 - - 0.00001416 54.0
HFD1_k127_4916996_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 351.0
HFD1_k127_4916996_4 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 298.0
HFD1_k127_4916996_5 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004666 279.0
HFD1_k127_4916996_6 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001956 282.0
HFD1_k127_4916996_7 MoeA domain protein domain I and II K03750 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000006011 273.0
HFD1_k127_4916996_8 Phosphoribosyl transferase domain K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000004327 218.0
HFD1_k127_4916996_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000006219 189.0
HFD1_k127_493490_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 496.0
HFD1_k127_493490_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 486.0
HFD1_k127_493490_2 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 387.0
HFD1_k127_493490_3 peptidoglycan biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000003402 244.0
HFD1_k127_493490_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000001443 223.0
HFD1_k127_493490_5 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000003303 188.0
HFD1_k127_493490_6 NfeD-like C-terminal, partner-binding - - - 0.000000000000000001748 92.0
HFD1_k127_4937300_0 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003105 275.0
HFD1_k127_4937300_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000002315 215.0
HFD1_k127_4937300_2 Uncharacterised ACR (DUF711) - - - 0.00000000004998 64.0
HFD1_k127_4991348_0 Dienelactone hydrolase family - - - 1.828e-272 849.0
HFD1_k127_4991348_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000003868 255.0
HFD1_k127_5006837_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 605.0
HFD1_k127_5006837_1 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 581.0
HFD1_k127_5006837_10 Protein of unknown function (DUF2490) - - - 0.000000000166 71.0
HFD1_k127_5006837_11 Histidine kinase - - - 0.000004376 55.0
HFD1_k127_5006837_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 465.0
HFD1_k127_5006837_3 SMART HTH transcriptional regulator, Crp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 307.0
HFD1_k127_5006837_4 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005303 254.0
HFD1_k127_5006837_5 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000001379 253.0
HFD1_k127_5006837_6 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000001389 241.0
HFD1_k127_5006837_7 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000008431 233.0
HFD1_k127_5006837_8 Copper amine oxidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000906 177.0
HFD1_k127_5006837_9 Domain of unknown function (DUF1844) - - - 0.0000000000000118 81.0
HFD1_k127_5026890_0 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 323.0
HFD1_k127_5026890_1 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000001501 230.0
HFD1_k127_5026890_2 DinB family - - - 0.0000000000000000000000003709 111.0
HFD1_k127_5026890_3 esterase - - - 0.000000001167 65.0
HFD1_k127_5066597_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 436.0
HFD1_k127_5066597_1 Histidine kinase - - - 0.0000005672 61.0
HFD1_k127_5066597_2 - - - - 0.000002859 58.0
HFD1_k127_5071017_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 478.0
HFD1_k127_5071017_1 Tyrosine recombinase xerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001302 265.0
HFD1_k127_5071017_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000001728 190.0
HFD1_k127_5071017_3 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.00000000000000000000000000000000000000000000004727 173.0
HFD1_k127_5071017_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000001013 125.0
HFD1_k127_5091074_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1286.0
HFD1_k127_5091074_1 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 418.0
HFD1_k127_5091074_10 Belongs to the 'phage' integrase family K04763 - - 0.000004674 53.0
HFD1_k127_5091074_11 - - - - 0.00002439 47.0
HFD1_k127_5091074_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00005706 49.0
HFD1_k127_5091074_2 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 418.0
HFD1_k127_5091074_3 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 303.0
HFD1_k127_5091074_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K03585 - - 0.0000000000000000000000000000000000000000000000000000000006612 218.0
HFD1_k127_5091074_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000001663 170.0
HFD1_k127_5091074_6 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000003689 160.0
HFD1_k127_5091074_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000005522 169.0
HFD1_k127_5091074_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000003139 147.0
HFD1_k127_5091074_9 Plasmid stabilization - - - 0.0000000000000000000000000625 108.0
HFD1_k127_51149_0 Major facilitator Superfamily K08178 - - 1.826e-196 618.0
HFD1_k127_51149_1 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 584.0
HFD1_k127_51149_10 Bacterial Ig-like domain (group 3) - - - 0.00000000000000000000000000000000000000000000000000000000000009465 237.0
HFD1_k127_51149_11 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000001805 206.0
HFD1_k127_51149_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000612 203.0
HFD1_k127_51149_13 EVE domain - - - 0.000000000000000000000000000000000000000000001809 173.0
HFD1_k127_51149_14 allantoin biosynthetic process K01477,K16840 - 3.5.3.4,4.1.1.97 0.00000000000000000000000000000000000000000002536 166.0
HFD1_k127_51149_15 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000008674 150.0
HFD1_k127_51149_16 Protein of unknown function (DUF3052) - - - 0.0000000000000000000000000000000001836 137.0
HFD1_k127_51149_17 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000003005 142.0
HFD1_k127_51149_18 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000003275 102.0
HFD1_k127_51149_19 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000000002529 88.0
HFD1_k127_51149_2 Belongs to the allantoicase family K01477 - 3.5.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 451.0
HFD1_k127_51149_20 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.00000000000000002673 85.0
HFD1_k127_51149_21 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000001046 63.0
HFD1_k127_51149_22 Redoxin K03386 - 1.11.1.15 0.000003059 53.0
HFD1_k127_51149_23 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' K03556 - - 0.000005176 57.0
HFD1_k127_51149_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 420.0
HFD1_k127_51149_4 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 358.0
HFD1_k127_51149_5 Subtilase family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 375.0
HFD1_k127_51149_6 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 316.0
HFD1_k127_51149_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003848 274.0
HFD1_k127_51149_8 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009302 274.0
HFD1_k127_51149_9 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007841 269.0
HFD1_k127_5142239_0 Succinyl-CoA ligase like flavodoxin domain - - - 0.0 1024.0
HFD1_k127_5142239_1 PFAM aminotransferase, class I K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 346.0
HFD1_k127_5142239_10 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.0000000000000000000002137 103.0
HFD1_k127_5142239_11 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 0.00008835 54.0
HFD1_k127_5142239_12 Bacterial protein of unknown function (DUF883) - - - 0.0008692 46.0
HFD1_k127_5142239_2 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
HFD1_k127_5142239_3 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000392 228.0
HFD1_k127_5142239_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000002631 221.0
HFD1_k127_5142239_5 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000000304 183.0
HFD1_k127_5142239_6 dehydrogenase complex catalyzes the overall conversion of - - - 0.000000000000000000000000000000000000000000003906 176.0
HFD1_k127_5142239_7 OsmC-like protein - - - 0.000000000000000000000000000000000000003917 151.0
HFD1_k127_5142239_8 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.0000000000000000000000000000000000008809 147.0
HFD1_k127_5142239_9 Urate oxidase N-terminal - - - 0.000000000000000000000000000000002725 139.0
HFD1_k127_5147856_0 - - - - 0.0 1096.0
HFD1_k127_5147856_1 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 1.377e-315 982.0
HFD1_k127_5147856_2 Beta-L-arabinofuranosidase, GH127 K09955 - - 2.889e-289 908.0
HFD1_k127_5147856_3 Carboxypeptidase regulatory-like domain - - - 1.119e-234 774.0
HFD1_k127_5147856_4 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002951 264.0
HFD1_k127_5160107_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 373.0
HFD1_k127_5160107_1 polysaccharide export protein K01991 - - 0.00000000000004578 83.0
HFD1_k127_5168946_0 hydrolase, family 3 K05349 - 3.2.1.21 0.0 1234.0
HFD1_k127_5168946_1 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1052.0
HFD1_k127_5168946_10 Beta-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 610.0
HFD1_k127_5168946_11 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 540.0
HFD1_k127_5168946_12 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 519.0
HFD1_k127_5168946_13 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 509.0
HFD1_k127_5168946_14 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 520.0
HFD1_k127_5168946_15 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 515.0
HFD1_k127_5168946_16 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 473.0
HFD1_k127_5168946_17 glucuronate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 461.0
HFD1_k127_5168946_18 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 434.0
HFD1_k127_5168946_19 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 432.0
HFD1_k127_5168946_2 Belongs to the glycosyl hydrolase 43 family K01198 - 3.2.1.37 4.341e-307 945.0
HFD1_k127_5168946_20 Sugar (and other) transporter K08178 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 425.0
HFD1_k127_5168946_21 mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 418.0
HFD1_k127_5168946_22 PFAM ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 403.0
HFD1_k127_5168946_23 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 375.0
HFD1_k127_5168946_24 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 376.0
HFD1_k127_5168946_25 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 390.0
HFD1_k127_5168946_26 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 360.0
HFD1_k127_5168946_27 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 332.0
HFD1_k127_5168946_28 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 347.0
HFD1_k127_5168946_29 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 321.0
HFD1_k127_5168946_3 Carboxypeptidase regulatory-like domain - - - 3.017e-284 915.0
HFD1_k127_5168946_30 peptidase S10 serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009968 283.0
HFD1_k127_5168946_31 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002357 260.0
HFD1_k127_5168946_32 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002423 270.0
HFD1_k127_5168946_33 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002812 249.0
HFD1_k127_5168946_34 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000001316 191.0
HFD1_k127_5168946_35 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000002915 205.0
HFD1_k127_5168946_36 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000004884 184.0
HFD1_k127_5168946_37 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000006706 103.0
HFD1_k127_5168946_38 PAS fold - - - 0.00000000000000000000009711 114.0
HFD1_k127_5168946_39 RNA polymerase sigma factor, sigma-70 family - - - 0.0000000000000000008224 93.0
HFD1_k127_5168946_4 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 2.085e-282 888.0
HFD1_k127_5168946_40 ECF sigma factor - - - 0.0000000000000005364 80.0
HFD1_k127_5168946_41 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000002462 69.0
HFD1_k127_5168946_42 Transcriptional regulatory protein, C terminal - - - 0.000000000005082 74.0
HFD1_k127_5168946_43 DNA-templated transcription, initiation K02405 - - 0.0000002514 55.0
HFD1_k127_5168946_44 CHAT domain - - - 0.00000133 54.0
HFD1_k127_5168946_45 Glycosyl hydrolase family 115 - - - 0.0001409 46.0
HFD1_k127_5168946_5 Carboxypeptidase regulatory-like domain - - - 1.586e-273 882.0
HFD1_k127_5168946_6 cellulose binding - - - 3.755e-250 803.0
HFD1_k127_5168946_7 Belongs to the peptidase S8 family - - - 2.864e-248 801.0
HFD1_k127_5168946_8 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 7.415e-227 707.0
HFD1_k127_5168946_9 PFAM Major Facilitator Superfamily K08191 - - 4.167e-203 639.0
HFD1_k127_5184645_0 PFAM DegT DnrJ EryC1 StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 596.0
HFD1_k127_5184645_1 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 410.0
HFD1_k127_5184645_10 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000003357 117.0
HFD1_k127_5184645_11 Methyltransferase domain - - - 0.00000000000000000001125 108.0
HFD1_k127_5184645_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000007088 59.0
HFD1_k127_5184645_2 Evidence 2b Function of strongly homologous gene K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 400.0
HFD1_k127_5184645_3 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 341.0
HFD1_k127_5184645_4 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000007456 254.0
HFD1_k127_5184645_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000001158 239.0
HFD1_k127_5184645_6 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000174 199.0
HFD1_k127_5184645_7 PFAM LmbE family protein - - - 0.000000000000000000000000000000284 143.0
HFD1_k127_5184645_8 methyltransferase - - - 0.00000000000000000000000001333 120.0
HFD1_k127_5184645_9 Methyltransferase domain - - - 0.00000000000000000000000596 113.0
HFD1_k127_522258_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.788e-292 915.0
HFD1_k127_522258_1 COG0457 FOG TPR repeat - - - 4.776e-238 748.0
HFD1_k127_522258_2 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 553.0
HFD1_k127_522258_3 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 396.0
HFD1_k127_522258_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000003385 194.0
HFD1_k127_5237665_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1236.0
HFD1_k127_5237665_1 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1220.0
HFD1_k127_5237665_10 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 398.0
HFD1_k127_5237665_11 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 365.0
HFD1_k127_5237665_12 protein tyrosine kinase activity K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 368.0
HFD1_k127_5237665_13 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 286.0
HFD1_k127_5237665_15 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001095 264.0
HFD1_k127_5237665_16 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001271 274.0
HFD1_k127_5237665_17 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 243.0
HFD1_k127_5237665_19 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000001266 201.0
HFD1_k127_5237665_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 1.056e-253 797.0
HFD1_k127_5237665_20 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000113 186.0
HFD1_k127_5237665_21 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000002149 179.0
HFD1_k127_5237665_22 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000006764 185.0
HFD1_k127_5237665_23 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.000000000000000000000000000000000000000000000139 172.0
HFD1_k127_5237665_24 BioY family K03523 - - 0.0000000000000000000000000000000000000000000001493 175.0
HFD1_k127_5237665_25 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000001714 174.0
HFD1_k127_5237665_26 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000001567 149.0
HFD1_k127_5237665_27 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000000000000000258 138.0
HFD1_k127_5237665_28 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000006427 133.0
HFD1_k127_5237665_29 - - - - 0.00000000000000000000000000005145 123.0
HFD1_k127_5237665_3 elongator protein 3 miab nifb - - - 4.821e-245 769.0
HFD1_k127_5237665_30 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000001906 128.0
HFD1_k127_5237665_31 Phosphoglycerate mutase family - - - 0.00000000000000000000000008044 113.0
HFD1_k127_5237665_32 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000188 106.0
HFD1_k127_5237665_33 - - - - 0.00000000000000000000006743 100.0
HFD1_k127_5237665_34 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000001271 104.0
HFD1_k127_5237665_35 CBS domain - - - 0.00000000000000000007288 95.0
HFD1_k127_5237665_37 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000009143 80.0
HFD1_k127_5237665_38 Universal stress protein family - - - 0.0000000000000002482 89.0
HFD1_k127_5237665_39 protein conserved in cyanobacteria - - - 0.00000000000002125 79.0
HFD1_k127_5237665_4 Carbon starvation protein K06200 - - 8.449e-218 692.0
HFD1_k127_5237665_40 - - - - 0.0000000001861 66.0
HFD1_k127_5237665_41 - - - - 0.000000001498 68.0
HFD1_k127_5237665_42 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000004569 69.0
HFD1_k127_5237665_43 lipolytic protein G-D-S-L family - - - 0.0000002359 62.0
HFD1_k127_5237665_44 PFAM peptidase M61 - - - 0.00002042 46.0
HFD1_k127_5237665_45 Vesicle coat trafficking protein Sec16 mid-region K20353 GO:0003400,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0005829,GO:0006810,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006950,GO:0006996,GO:0007029,GO:0007030,GO:0007154,GO:0008104,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010256,GO:0012505,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0017016,GO:0019899,GO:0022607,GO:0031267,GO:0031667,GO:0031668,GO:0031669,GO:0032386,GO:0032388,GO:0032879,GO:0032880,GO:0033036,GO:0033043,GO:0033157,GO:0033365,GO:0033554,GO:0034198,GO:0034613,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043933,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048209,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051049,GO:0051050,GO:0051128,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0051716,GO:0060341,GO:0060627,GO:0060628,GO:0061024,GO:0065003,GO:0065007,GO:0070201,GO:0070727,GO:0070861,GO:0070863,GO:0070971,GO:0070972,GO:0070973,GO:0071496,GO:0071840,GO:0090087,GO:0090113,GO:0090114,GO:0090316,GO:1903827,GO:1903829,GO:1904951,GO:1990928 - 0.0009028 47.0
HFD1_k127_5237665_46 Putative zinc-finger - - - 0.0009364 50.0
HFD1_k127_5237665_5 PFAM Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 602.0
HFD1_k127_5237665_6 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 552.0
HFD1_k127_5237665_7 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 456.0
HFD1_k127_5237665_8 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 447.0
HFD1_k127_5237665_9 Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 398.0
HFD1_k127_5250516_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 576.0
HFD1_k127_5250516_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 498.0
HFD1_k127_5250516_10 diguanylate cyclase - - - 0.000000000000000000000000000000000001724 153.0
HFD1_k127_5250516_11 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000001268 120.0
HFD1_k127_5250516_12 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.0000000000000000000000000004044 115.0
HFD1_k127_5250516_13 - - - - 0.00000000000000000000000004205 111.0
HFD1_k127_5250516_14 addiction module antidote protein, HigA family K21498 - - 0.000000000000000000000000327 108.0
HFD1_k127_5250516_15 SnoaL-like polyketide cyclase - - - 0.00000000000000000003109 94.0
HFD1_k127_5250516_16 Protein conserved in bacteria - - - 0.000002205 50.0
HFD1_k127_5250516_2 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 456.0
HFD1_k127_5250516_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 375.0
HFD1_k127_5250516_4 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 268.0
HFD1_k127_5250516_5 PFAM Cache K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000225 254.0
HFD1_k127_5250516_6 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000002002 220.0
HFD1_k127_5250516_7 Peptidase family M23 K21472 - - 0.0000000000000000000000000000000000000000000000006409 183.0
HFD1_k127_5250516_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000202 187.0
HFD1_k127_5250516_9 Single Cache domain 2 K07647 - 2.7.13.3 0.00000000000000000000000000000000000000001142 173.0
HFD1_k127_5291398_0 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 381.0
HFD1_k127_5291398_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000002986 274.0
HFD1_k127_5291398_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002178 256.0
HFD1_k127_5291398_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003525 243.0
HFD1_k127_5291398_4 JAB/MPN domain - - - 0.0000000001566 66.0
HFD1_k127_5291398_5 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0001157 47.0
HFD1_k127_5296647_0 FeS assembly protein SufB K09014 - - 3.189e-251 782.0
HFD1_k127_5296647_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 576.0
HFD1_k127_5296647_10 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 291.0
HFD1_k127_5296647_11 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004998 282.0
HFD1_k127_5296647_12 response regulator, receiver K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001121 252.0
HFD1_k127_5296647_13 response regulator, receiver K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000106 243.0
HFD1_k127_5296647_14 endonuclease I - - - 0.00000000000000000000000000000000000000000000000000000000006943 232.0
HFD1_k127_5296647_15 NifU-like N terminal domain K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000001101 198.0
HFD1_k127_5296647_16 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000000000000000007268 209.0
HFD1_k127_5296647_17 - - - - 0.00000000000000000000000000000000000003322 147.0
HFD1_k127_5296647_18 Lamin Tail Domain - - - 0.00000000000000000000000000000000000296 161.0
HFD1_k127_5296647_19 domain protein K13735 - - 0.0000000000000000000000000001758 135.0
HFD1_k127_5296647_2 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 443.0
HFD1_k127_5296647_20 Transcriptional regulator - - - 0.0000000000000000000000001447 112.0
HFD1_k127_5296647_22 bacterial-type flagellum-dependent cell motility - - - 0.000000000000001861 92.0
HFD1_k127_5296647_3 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 443.0
HFD1_k127_5296647_4 Thrombospondin type 3 repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 424.0
HFD1_k127_5296647_5 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 383.0
HFD1_k127_5296647_6 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 343.0
HFD1_k127_5296647_7 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 331.0
HFD1_k127_5296647_8 neuron death in response to oxidative stress K01173,K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 353.0
HFD1_k127_5296647_9 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 293.0
HFD1_k127_531536_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002507 312.0
HFD1_k127_5368118_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 375.0
HFD1_k127_5368118_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000001515 221.0
HFD1_k127_5368118_2 outer membrane efflux protein K15725 - - 0.000000000000000000000000000000002139 143.0
HFD1_k127_5386634_0 MacB-like periplasmic core domain - - - 2.899e-274 865.0
HFD1_k127_5386634_1 efflux transmembrane transporter activity - - - 4.129e-247 787.0
HFD1_k127_5386634_10 efflux transmembrane transporter activity - - - 1.311e-198 647.0
HFD1_k127_5386634_11 MacB-like periplasmic core domain - - - 7.939e-198 644.0
HFD1_k127_5386634_12 MacB-like periplasmic core domain - - - 3.579e-196 640.0
HFD1_k127_5386634_13 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 621.0
HFD1_k127_5386634_14 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 596.0
HFD1_k127_5386634_15 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 575.0
HFD1_k127_5386634_16 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 563.0
HFD1_k127_5386634_17 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 520.0
HFD1_k127_5386634_18 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 503.0
HFD1_k127_5386634_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 431.0
HFD1_k127_5386634_2 MacB-like periplasmic core domain - - - 1.325e-240 767.0
HFD1_k127_5386634_20 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 383.0
HFD1_k127_5386634_21 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 347.0
HFD1_k127_5386634_22 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 336.0
HFD1_k127_5386634_23 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 306.0
HFD1_k127_5386634_24 MacB-like periplasmic core domain - - - 0.000000000000000000000000000003637 123.0
HFD1_k127_5386634_25 efflux transmembrane transporter activity - - - 0.00000002241 62.0
HFD1_k127_5386634_26 MacB-like periplasmic core domain - - - 0.0000003592 53.0
HFD1_k127_5386634_3 MacB-like periplasmic core domain - - - 3.275e-223 717.0
HFD1_k127_5386634_4 efflux transmembrane transporter activity K02004 - - 3.564e-221 711.0
HFD1_k127_5386634_5 efflux transmembrane transporter activity K02004 - - 1.205e-211 684.0
HFD1_k127_5386634_6 efflux transmembrane transporter activity K02004 - - 1.392e-207 672.0
HFD1_k127_5386634_7 efflux transmembrane transporter activity K02004 - - 1.041e-206 673.0
HFD1_k127_5386634_8 efflux transmembrane transporter activity - - - 1.377e-201 656.0
HFD1_k127_5386634_9 efflux transmembrane transporter activity K02004 - - 1.843e-201 654.0
HFD1_k127_5395141_0 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 338.0
HFD1_k127_5395141_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 317.0
HFD1_k127_5395141_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 307.0
HFD1_k127_5395141_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000001045 235.0
HFD1_k127_5395141_4 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000003963 214.0
HFD1_k127_5395141_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000001342 203.0
HFD1_k127_5395141_6 Transport permease protein K01992 - - 0.000000000000000000000000000002466 130.0
HFD1_k127_5395141_7 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000006443 120.0
HFD1_k127_5395141_8 Insulinase (Peptidase family M16) - - - 0.000000000000002043 89.0
HFD1_k127_5395141_9 Gram-negative bacterial TonB protein C-terminal - - - 0.000000002035 70.0
HFD1_k127_5413329_0 Tricorn protease C1 domain K08676 - - 0.0 1272.0
HFD1_k127_5413329_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 5.987e-286 904.0
HFD1_k127_5413329_10 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 471.0
HFD1_k127_5413329_11 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 445.0
HFD1_k127_5413329_12 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 443.0
HFD1_k127_5413329_13 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 462.0
HFD1_k127_5413329_14 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 430.0
HFD1_k127_5413329_15 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 383.0
HFD1_k127_5413329_16 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 391.0
HFD1_k127_5413329_17 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 365.0
HFD1_k127_5413329_18 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 353.0
HFD1_k127_5413329_19 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 312.0
HFD1_k127_5413329_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 5.26e-259 817.0
HFD1_k127_5413329_20 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 308.0
HFD1_k127_5413329_21 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001342 291.0
HFD1_k127_5413329_22 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000153 276.0
HFD1_k127_5413329_23 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008375 269.0
HFD1_k127_5413329_24 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005796 239.0
HFD1_k127_5413329_25 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000363 239.0
HFD1_k127_5413329_26 NAD dependent epimerase/dehydratase family K07535 - - 0.000000000000000000000000000000000000000000000000000000000000000005301 236.0
HFD1_k127_5413329_27 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000002745 220.0
HFD1_k127_5413329_28 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000009851 202.0
HFD1_k127_5413329_29 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000004454 208.0
HFD1_k127_5413329_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 3.847e-219 692.0
HFD1_k127_5413329_31 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000001952 184.0
HFD1_k127_5413329_32 PFAM Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000002368 181.0
HFD1_k127_5413329_33 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000001188 180.0
HFD1_k127_5413329_34 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000000000000001572 169.0
HFD1_k127_5413329_35 Prephenate dehydrogenase K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 0.000000000000000000000000000000000000000000001909 177.0
HFD1_k127_5413329_36 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000005963 179.0
HFD1_k127_5413329_37 - - - - 0.0000000000000000000000000000000000000000001951 166.0
HFD1_k127_5413329_38 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000000000001547 156.0
HFD1_k127_5413329_39 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000007688 156.0
HFD1_k127_5413329_4 Peptidase S46 - - - 4.563e-219 701.0
HFD1_k127_5413329_40 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000001284 167.0
HFD1_k127_5413329_41 Universal stress protein family - - - 0.00000000000000000000000000000000000008272 155.0
HFD1_k127_5413329_42 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000001883 135.0
HFD1_k127_5413329_43 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000362 138.0
HFD1_k127_5413329_44 DNA polymerase K02347 - - 0.00000000000000000000000000002451 123.0
HFD1_k127_5413329_45 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000003269 128.0
HFD1_k127_5413329_46 holo-[acyl-carrier-protein] synthase activity K00997,K01207 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 0.00000000000000000000000003426 112.0
HFD1_k127_5413329_47 PFAM response regulator receiver K11443 - - 0.0000000000000000000000005105 109.0
HFD1_k127_5413329_48 SpoVT / AbrB like domain K07172 - - 0.000000000000000000000008355 102.0
HFD1_k127_5413329_49 von Willebrand factor, type A - - - 0.000000000000000000006777 107.0
HFD1_k127_5413329_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.303e-205 645.0
HFD1_k127_5413329_50 Chorismate mutase type II K04093 - 5.4.99.5 0.0000000000000000005491 91.0
HFD1_k127_5413329_51 SEC-C Motif Domain Protein - - - 0.0000000000000000106 90.0
HFD1_k127_5413329_52 Universal stress protein family - - - 0.0000000000000005301 89.0
HFD1_k127_5413329_53 AMP binding K06149 - - 0.0000000000000005301 89.0
HFD1_k127_5413329_54 Disulphide bond corrector protein DsbC K04084,K06888 - 1.8.1.8 0.0000000000001113 78.0
HFD1_k127_5413329_55 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000001144 84.0
HFD1_k127_5413329_56 COG1918 Fe2 transport system protein A K04758 - - 0.00000000001258 67.0
HFD1_k127_5413329_57 - - - - 0.0000000002685 64.0
HFD1_k127_5413329_58 Alcohol dehydrogenase GroES-like domain K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.000000003279 61.0
HFD1_k127_5413329_59 SEC-C Motif Domain Protein - - - 0.000000005217 64.0
HFD1_k127_5413329_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 617.0
HFD1_k127_5413329_60 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.00000003292 60.0
HFD1_k127_5413329_61 Polysaccharide biosynthesis/export protein K01991 - - 0.00000003516 66.0
HFD1_k127_5413329_62 PFAM zinc finger, DksA TraR C4-type - - - 0.00000004244 61.0
HFD1_k127_5413329_63 peptidyl-tyrosine sulfation - - - 0.000007195 58.0
HFD1_k127_5413329_64 PA-IL-like protein K20258 - - 0.000321 52.0
HFD1_k127_5413329_7 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 567.0
HFD1_k127_5413329_8 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 555.0
HFD1_k127_5413329_9 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 469.0
HFD1_k127_5422941_0 SMART Elongator protein 3 MiaB NifB - - - 6.844e-219 689.0
HFD1_k127_5422941_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 455.0
HFD1_k127_5422941_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000001223 219.0
HFD1_k127_5422941_11 - - - - 0.000000000000000000000000000000000000000000000000001543 192.0
HFD1_k127_5422941_12 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000001791 157.0
HFD1_k127_5422941_13 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000001798 156.0
HFD1_k127_5422941_14 Cna B domain protein - - - 0.0000000000000000000000000000000000005882 164.0
HFD1_k127_5422941_15 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000007283 143.0
HFD1_k127_5422941_16 STAS domain K04749 - - 0.00000000000000000000000000000000001717 138.0
HFD1_k127_5422941_17 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000001371 132.0
HFD1_k127_5422941_18 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000004343 138.0
HFD1_k127_5422941_19 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000597 110.0
HFD1_k127_5422941_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 403.0
HFD1_k127_5422941_20 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000002794 109.0
HFD1_k127_5422941_21 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000001266 91.0
HFD1_k127_5422941_22 membrane K08988 - - 0.0000000000000000004199 95.0
HFD1_k127_5422941_23 peptidyl-tyrosine sulfation - - - 0.000000000001448 80.0
HFD1_k127_5422941_24 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00006951 58.0
HFD1_k127_5422941_3 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 435.0
HFD1_k127_5422941_4 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 394.0
HFD1_k127_5422941_5 Transporter-associated region K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 394.0
HFD1_k127_5422941_6 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 340.0
HFD1_k127_5422941_7 Tim44 K15539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 317.0
HFD1_k127_5422941_8 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 303.0
HFD1_k127_5422941_9 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001337 280.0
HFD1_k127_5435168_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 290.0
HFD1_k127_5435168_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 291.0
HFD1_k127_5435168_2 PFAM Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001786 295.0
HFD1_k127_5435168_3 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.00000000000000000000000000002566 126.0
HFD1_k127_5436134_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 1.978e-207 665.0
HFD1_k127_5436134_1 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 586.0
HFD1_k127_5436134_10 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 302.0
HFD1_k127_5436134_11 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004635 296.0
HFD1_k127_5436134_12 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006749 291.0
HFD1_k127_5436134_13 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000729 277.0
HFD1_k127_5436134_14 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000455 235.0
HFD1_k127_5436134_15 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000001124 217.0
HFD1_k127_5436134_16 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000004129 207.0
HFD1_k127_5436134_17 GGDEF domain - - - 0.000000000000000000000000000000000000000000000007032 184.0
HFD1_k127_5436134_18 - - - - 0.0000000000000000000000000000000000000000008869 180.0
HFD1_k127_5436134_19 - - - - 0.00000000000000000000000000000000002625 154.0
HFD1_k127_5436134_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 557.0
HFD1_k127_5436134_20 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000000000000000000000000000000002899 145.0
HFD1_k127_5436134_21 Protein of unknown function DUF84 - GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.0000000000000000000000000004768 121.0
HFD1_k127_5436134_22 phosphorelay signal transduction system - - - 0.00000000002219 76.0
HFD1_k127_5436134_23 repeat-containing protein - - - 0.000000001126 70.0
HFD1_k127_5436134_24 self proteolysis - - - 0.0000003624 62.0
HFD1_k127_5436134_25 peptidyl-tyrosine sulfation - - - 0.0000008006 61.0
HFD1_k127_5436134_26 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000942 57.0
HFD1_k127_5436134_27 Gram-negative bacterial TonB protein C-terminal - - - 0.0000591 55.0
HFD1_k127_5436134_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 478.0
HFD1_k127_5436134_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 460.0
HFD1_k127_5436134_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 386.0
HFD1_k127_5436134_6 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 375.0
HFD1_k127_5436134_7 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 395.0
HFD1_k127_5436134_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 325.0
HFD1_k127_5436134_9 PFAM peptidase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 314.0
HFD1_k127_5468213_0 transport - - - 0.0 1244.0
HFD1_k127_5468213_1 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 8.77e-253 793.0
HFD1_k127_5468213_10 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000001295 156.0
HFD1_k127_5468213_11 PFAM Heparinase II III-like protein - - - 0.000000000000000000000000000000004942 147.0
HFD1_k127_5468213_12 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000001717 145.0
HFD1_k127_5468213_13 Peptidase S1 and S6 chymotrypsin Hap - - - 0.00000000000000000000000000002483 129.0
HFD1_k127_5468213_14 DinB superfamily - - - 0.00000000000000387 85.0
HFD1_k127_5468213_15 Transcriptional regulatory protein, C terminal - - - 0.000000000000007962 79.0
HFD1_k127_5468213_16 penicillin amidase K01434 - 3.5.1.11 0.00000000002665 64.0
HFD1_k127_5468213_17 Helix-turn-helix XRE-family like proteins - - - 0.0000000000409 65.0
HFD1_k127_5468213_18 alpha/beta hydrolase fold - - - 0.000000001307 70.0
HFD1_k127_5468213_2 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 6.74e-203 648.0
HFD1_k127_5468213_20 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000002935 51.0
HFD1_k127_5468213_21 Tetratricopeptide repeat - - - 0.0004679 46.0
HFD1_k127_5468213_3 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 458.0
HFD1_k127_5468213_4 Domain of unknown function (DUF3471) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 387.0
HFD1_k127_5468213_5 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 350.0
HFD1_k127_5468213_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 314.0
HFD1_k127_5468213_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
HFD1_k127_5468213_8 Belongs to the RutC family K09021,K15067 - 3.5.99.5 0.000000000000000000000000000000000000000000000000001293 192.0
HFD1_k127_5468213_9 - - - - 0.0000000000000000000000000000000000000000000001043 170.0
HFD1_k127_55368_0 His Kinase A (phosphoacceptor) domain - - - 1.089e-205 670.0
HFD1_k127_55368_1 cell adhesion involved in biofilm formation K02014,K11031 - - 5.95e-200 671.0
HFD1_k127_55368_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000003759 220.0
HFD1_k127_55368_11 methylisocitrate lyase activity K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000009864 222.0
HFD1_k127_55368_12 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000011 147.0
HFD1_k127_55368_13 Transglycosylase associated protein - - - 0.0000000000000000000001376 107.0
HFD1_k127_55368_14 Protein of unknown function (DUF664) - - - 0.00000000000000001206 89.0
HFD1_k127_55368_15 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000002388 85.0
HFD1_k127_55368_16 Protein of unknown function (DUF433) - - - 0.000003911 50.0
HFD1_k127_55368_17 Protein of unknown function (DUF433) - - - 0.00004633 46.0
HFD1_k127_55368_18 PFAM helix-turn-helix, Fis-type - - - 0.0001674 47.0
HFD1_k127_55368_19 bacterial OsmY and nodulation domain - - - 0.0003659 50.0
HFD1_k127_55368_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 380.0
HFD1_k127_55368_20 COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain K03974 - - 0.0006253 47.0
HFD1_k127_55368_21 phosphorelay signal transduction system - - - 0.0009976 49.0
HFD1_k127_55368_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 407.0
HFD1_k127_55368_4 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 366.0
HFD1_k127_55368_5 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 357.0
HFD1_k127_55368_6 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 338.0
HFD1_k127_55368_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 353.0
HFD1_k127_55368_8 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 286.0
HFD1_k127_55368_9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000004477 227.0
HFD1_k127_5552549_0 PFAM NHL repeat - - - 4.337e-194 627.0
HFD1_k127_5552549_1 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 296.0
HFD1_k127_5552549_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
HFD1_k127_5552549_3 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000001003 215.0
HFD1_k127_5552549_4 PFAM NIPSNAP family containing protein - - - 0.00000000000000000000000000000000000000000000000000001623 194.0
HFD1_k127_5552549_5 - - - - 0.000000000000000000000000000000000001095 145.0
HFD1_k127_5552549_6 - - - - 0.00000000000000000001469 97.0
HFD1_k127_5552549_7 - - - - 0.00000000000000007167 85.0
HFD1_k127_5570254_0 Belongs to the glycosyl hydrolase 2 family - - - 1.471e-259 842.0
HFD1_k127_5570254_1 COG NOG06097 non supervised orthologous group - - - 1.877e-204 659.0
HFD1_k127_5570254_2 F5 8 type C domain protein K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 613.0
HFD1_k127_5570254_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 445.0
HFD1_k127_5570254_4 arabinan catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 413.0
HFD1_k127_5570254_5 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 325.0
HFD1_k127_5597492_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1133.0
HFD1_k127_5597492_1 ThiS family K21029,K21147 - 2.7.7.80,2.8.1.11 2.489e-197 626.0
HFD1_k127_5597492_2 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 403.0
HFD1_k127_5597492_3 Cys Met metabolism K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 359.0
HFD1_k127_5597492_4 JAB/MPN domain - - - 0.00000000000000000000000000000000000000000001959 166.0
HFD1_k127_5597492_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000001416 107.0
HFD1_k127_5597492_6 - - - - 0.00000000000000000000002089 102.0
HFD1_k127_5597492_7 Protein of unknown function (DUF433) - - - 0.00000000000000000000003104 102.0
HFD1_k127_5634557_0 penicillin amidase K01434 - 3.5.1.11 1.657e-237 747.0
HFD1_k127_5634557_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 357.0
HFD1_k127_5652882_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 1.952e-243 772.0
HFD1_k127_5652882_1 Carboxypeptidase regulatory-like domain - - - 1.668e-239 774.0
HFD1_k127_5652882_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000000000000000000007202 216.0
HFD1_k127_5652882_11 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000001607 216.0
HFD1_k127_5652882_12 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000001553 207.0
HFD1_k127_5652882_13 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000756 212.0
HFD1_k127_5652882_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.00000000000000000000000000000000000000000000000000002567 197.0
HFD1_k127_5652882_15 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000008111 205.0
HFD1_k127_5652882_16 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000001219 157.0
HFD1_k127_5652882_17 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000001031 142.0
HFD1_k127_5652882_18 Lamin Tail Domain K07004 - - 0.000000000000000000000000000000004681 147.0
HFD1_k127_5652882_19 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000001303 120.0
HFD1_k127_5652882_2 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 1.279e-210 672.0
HFD1_k127_5652882_20 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000003757 121.0
HFD1_k127_5652882_21 - - - - 0.0000000000000000000000000004259 116.0
HFD1_k127_5652882_22 TIR domain - - - 0.0000000000000000000000001608 118.0
HFD1_k127_5652882_23 - - - - 0.0000000000000000000000008198 114.0
HFD1_k127_5652882_24 Glyoxalase-like domain - - - 0.000000000000000000000006522 116.0
HFD1_k127_5652882_25 Protein of unknown function (DUF971) - - - 0.00000000000000000000001213 103.0
HFD1_k127_5652882_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000001566 112.0
HFD1_k127_5652882_27 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000003714 108.0
HFD1_k127_5652882_28 Peptidase C14 caspase catalytic subunit p20 K07126 - - 0.000000000000000000005964 109.0
HFD1_k127_5652882_29 Polysaccharide export protein K01991,K20988 - - 0.000000000000000002096 97.0
HFD1_k127_5652882_3 Elongation factor G, domain IV K02355 - - 1.221e-197 637.0
HFD1_k127_5652882_30 peptidyl-tyrosine sulfation - - - 0.000000000000001532 91.0
HFD1_k127_5652882_31 Domain of unknown function (DUF4384) - - - 0.0000000000002319 80.0
HFD1_k127_5652882_32 general stress protein - - - 0.00000000004162 69.0
HFD1_k127_5652882_33 - - - - 0.000000000146 62.0
HFD1_k127_5652882_34 Protein of unknown function, DUF393 - - - 0.0000000003041 67.0
HFD1_k127_5652882_36 - - - - 0.00000003488 55.0
HFD1_k127_5652882_37 Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.000000297 58.0
HFD1_k127_5652882_38 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000007894 60.0
HFD1_k127_5652882_39 Tetratricopeptide repeat - - - 0.000001869 61.0
HFD1_k127_5652882_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 447.0
HFD1_k127_5652882_40 Prolyl oligopeptidase K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 0.00004023 50.0
HFD1_k127_5652882_41 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.00005689 52.0
HFD1_k127_5652882_42 - - - - 0.0003709 52.0
HFD1_k127_5652882_5 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 367.0
HFD1_k127_5652882_6 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 346.0
HFD1_k127_5652882_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 353.0
HFD1_k127_5652882_8 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001479 285.0
HFD1_k127_5652882_9 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000152 277.0
HFD1_k127_5658651_0 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 458.0
HFD1_k127_5658651_1 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 421.0
HFD1_k127_5658651_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005733 245.0
HFD1_k127_5658651_3 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006426 250.0
HFD1_k127_5658651_4 NAD dependent epimerase/dehydratase family K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000006427 241.0
HFD1_k127_5658651_5 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000673 162.0
HFD1_k127_5658651_6 Beta-lactamase - - - 0.000000000001608 81.0
HFD1_k127_5682086_0 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 387.0
HFD1_k127_5682086_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001642 256.0
HFD1_k127_5682086_2 conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000003709 226.0
HFD1_k127_5682086_3 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000000006904 143.0
HFD1_k127_5682086_4 - - - - 0.0000000000001512 77.0
HFD1_k127_5682086_5 AMP-binding enzyme C-terminal domain - - - 0.0001032 45.0
HFD1_k127_5724263_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 477.0
HFD1_k127_5724263_1 Calx-beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 356.0
HFD1_k127_5724263_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000002996 218.0
HFD1_k127_5724263_3 PFAM regulatory protein TetR K13770 - - 0.0000000000000000000000000000000000000000000003467 176.0
HFD1_k127_5740563_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1274.0
HFD1_k127_5740563_1 Carboxypeptidase regulatory-like domain - - - 7.609e-292 935.0
HFD1_k127_5740563_10 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.00000000000000000000000000000000000005833 145.0
HFD1_k127_5740563_11 LUD domain K00782 - - 0.0000000000000000000001397 107.0
HFD1_k127_5740563_12 Transposase IS200 like - - - 0.00000008033 55.0
HFD1_k127_5740563_13 Cysteine-rich domain K18928 - - 0.00003331 46.0
HFD1_k127_5740563_2 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 1.486e-268 844.0
HFD1_k127_5740563_3 polygalacturonase activity K01184 - 3.2.1.15 5.73e-199 631.0
HFD1_k127_5740563_4 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 2.067e-197 627.0
HFD1_k127_5740563_5 Sialate O-acetylesterase K05970 - 3.1.1.53 1.469e-194 619.0
HFD1_k127_5740563_6 Oligogalacturonate lyase K01730 - 4.2.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 490.0
HFD1_k127_5740563_7 TIGRFAM iron-sulfur cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 480.0
HFD1_k127_5740563_8 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 476.0
HFD1_k127_5740563_9 Branched-chain amino acid transport system / permease component K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 334.0
HFD1_k127_5843960_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 288.0
HFD1_k127_5843960_1 AMP binding - - - 0.000000000000000000000003366 113.0
HFD1_k127_5843960_2 Universal stress protein family - - - 0.00000000000000000002168 102.0
HFD1_k127_5889941_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 4.667e-289 913.0
HFD1_k127_5889941_1 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 595.0
HFD1_k127_5889941_10 HYR domain - - - 0.00000000000000000000000000000002502 131.0
HFD1_k127_5889941_11 response regulator - - - 0.00000000000000000000000000006363 131.0
HFD1_k127_5889941_12 Xanthine and CO dehydrogenases maturation factor XdhC CoxF K07402 - - 0.0000000000000000000000584 102.0
HFD1_k127_5889941_13 TIR domain - - - 0.0000000001018 69.0
HFD1_k127_5889941_2 Pectate lyase K01728 - 4.2.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 455.0
HFD1_k127_5889941_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 306.0
HFD1_k127_5889941_4 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000005372 258.0
HFD1_k127_5889941_5 histone H2A K63-linked ubiquitination K11894,K11913,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000004459 199.0
HFD1_k127_5889941_6 - - - - 0.000000000000000000000000000000000000000000000000000009305 197.0
HFD1_k127_5889941_7 cellulose binding - - - 0.000000000000000000000000000000000000000000003357 176.0
HFD1_k127_5889941_8 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000000103 138.0
HFD1_k127_5889941_9 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000002117 146.0
HFD1_k127_5920607_0 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 584.0
HFD1_k127_5920607_1 - K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 466.0
HFD1_k127_5920607_10 - - - - 0.0000000000000000000000000000421 118.0
HFD1_k127_5920607_11 - - - - 0.00000000000000000000591 94.0
HFD1_k127_5920607_12 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000008616 96.0
HFD1_k127_5920607_13 Transposase IS200 like - - - 0.00000000000000000002746 96.0
HFD1_k127_5920607_2 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 456.0
HFD1_k127_5920607_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 340.0
HFD1_k127_5920607_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 335.0
HFD1_k127_5920607_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 321.0
HFD1_k127_5920607_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 312.0
HFD1_k127_5920607_7 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 308.0
HFD1_k127_5920607_8 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000001268 246.0
HFD1_k127_5920607_9 DinB superfamily - - - 0.00000000000000000000000000000000007078 141.0
HFD1_k127_5930297_0 Tricorn protease homolog K08676 - - 0.0 1491.0
HFD1_k127_5930297_1 helicase activity - - - 0.0 1090.0
HFD1_k127_5930297_10 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 378.0
HFD1_k127_5930297_11 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 353.0
HFD1_k127_5930297_12 copper resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 332.0
HFD1_k127_5930297_13 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 297.0
HFD1_k127_5930297_14 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 291.0
HFD1_k127_5930297_15 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 294.0
HFD1_k127_5930297_16 DEAD DEAH box helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002729 259.0
HFD1_k127_5930297_17 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001054 253.0
HFD1_k127_5930297_18 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000004509 241.0
HFD1_k127_5930297_19 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000004971 241.0
HFD1_k127_5930297_2 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 5.539e-302 940.0
HFD1_k127_5930297_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000534 234.0
HFD1_k127_5930297_21 DSHCT - - - 0.00000000000000000000000000000000000000000000000000000000000007656 236.0
HFD1_k127_5930297_22 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000003682 210.0
HFD1_k127_5930297_23 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000001247 213.0
HFD1_k127_5930297_24 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000591 179.0
HFD1_k127_5930297_25 Cation transport regulator - - - 0.0000000000000000000000000000000000000000002167 164.0
HFD1_k127_5930297_26 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000002963 157.0
HFD1_k127_5930297_27 YjbR - - - 0.000000000000000000000000000000002361 132.0
HFD1_k127_5930297_28 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000239 134.0
HFD1_k127_5930297_29 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000411 122.0
HFD1_k127_5930297_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.959e-253 800.0
HFD1_k127_5930297_30 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000002847 116.0
HFD1_k127_5930297_31 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000001593 104.0
HFD1_k127_5930297_32 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000294 114.0
HFD1_k127_5930297_33 Redoxin - - - 0.00000000000000000002071 104.0
HFD1_k127_5930297_34 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000002219 89.0
HFD1_k127_5930297_35 YCII-related domain - - - 0.0000000000000000003925 100.0
HFD1_k127_5930297_36 Helix-hairpin-helix motif - - - 0.0000000000000003216 82.0
HFD1_k127_5930297_37 Putative restriction endonuclease - - - 0.0000000000000006539 85.0
HFD1_k127_5930297_38 Stress responsive A/B Barrel Domain - - - 0.00000000000001376 77.0
HFD1_k127_5930297_4 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 592.0
HFD1_k127_5930297_40 - - - - 0.0000000000001232 73.0
HFD1_k127_5930297_41 Membrane-flanked domain-containing protein - - - 0.000000009352 64.0
HFD1_k127_5930297_42 YCII-related domain - - - 0.00000001329 67.0
HFD1_k127_5930297_43 Putative peptidoglycan binding domain - - - 0.000001405 55.0
HFD1_k127_5930297_44 PD-(D/E)XK nuclease superfamily - - - 0.000003476 48.0
HFD1_k127_5930297_45 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00001536 55.0
HFD1_k127_5930297_46 FecR protein - - - 0.00004757 55.0
HFD1_k127_5930297_5 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 542.0
HFD1_k127_5930297_6 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 519.0
HFD1_k127_5930297_7 Peptidase, S9A B C family, catalytic domain protein K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 497.0
HFD1_k127_5930297_8 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 454.0
HFD1_k127_5930297_9 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 387.0
HFD1_k127_5957412_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1106.0
HFD1_k127_5957412_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.122e-293 921.0
HFD1_k127_5957412_10 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 325.0
HFD1_k127_5957412_11 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 301.0
HFD1_k127_5957412_12 transmembrane transport K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 292.0
HFD1_k127_5957412_13 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 290.0
HFD1_k127_5957412_14 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001591 291.0
HFD1_k127_5957412_15 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000001147 241.0
HFD1_k127_5957412_16 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000002009 236.0
HFD1_k127_5957412_17 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000004458 239.0
HFD1_k127_5957412_18 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.000000000000000000000000000000000000000000000000000000000000001459 227.0
HFD1_k127_5957412_19 PFAM KWG Leptospira - - - 0.0000000000000000000000000000000000000000000000000000000001711 228.0
HFD1_k127_5957412_2 Dienelactone hydrolase family - - - 6.17e-224 714.0
HFD1_k127_5957412_20 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000001321 201.0
HFD1_k127_5957412_21 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000002399 193.0
HFD1_k127_5957412_22 - - - - 0.000000000000000000000000000000000000000000001167 175.0
HFD1_k127_5957412_23 - - - - 0.000000000000000000000000000000000000000000002299 171.0
HFD1_k127_5957412_24 DinB family - - - 0.000000000000000000000000000000003833 134.0
HFD1_k127_5957412_25 Transposase IS200 like K07491 - - 0.000000000000000000000000000000216 131.0
HFD1_k127_5957412_26 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.000000000000000000000000000001283 134.0
HFD1_k127_5957412_27 Putative restriction endonuclease - - - 0.000000000000000000000007388 108.0
HFD1_k127_5957412_28 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000002988 90.0
HFD1_k127_5957412_29 Tetratricopeptide repeat - - - 0.000000001324 70.0
HFD1_k127_5957412_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.693e-204 653.0
HFD1_k127_5957412_30 STAS domain K04749 - - 0.000000005482 62.0
HFD1_k127_5957412_31 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000002307 67.0
HFD1_k127_5957412_32 Zinc-binding dehydrogenase - - - 0.0007563 44.0
HFD1_k127_5957412_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 418.0
HFD1_k127_5957412_5 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 405.0
HFD1_k127_5957412_6 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 375.0
HFD1_k127_5957412_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 374.0
HFD1_k127_5957412_8 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 336.0
HFD1_k127_5957412_9 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 323.0
HFD1_k127_5982455_0 cellulose binding - - - 0.0 1352.0
HFD1_k127_5982455_1 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1173.0
HFD1_k127_5982455_10 - - - - 0.000000000000000000000000000000000000000000000006335 182.0
HFD1_k127_5982455_11 - - - - 0.0000000000000000000000000000000000000000000005789 175.0
HFD1_k127_5982455_12 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000001564 152.0
HFD1_k127_5982455_13 Transcriptional regulatory protein - - - 0.000000000001007 73.0
HFD1_k127_5982455_14 cAMP biosynthetic process - - - 0.000001647 56.0
HFD1_k127_5982455_15 cAMP biosynthetic process - - - 0.00005403 47.0
HFD1_k127_5982455_2 Serine threonine protein kinase K12132 - 2.7.11.1 4.107e-210 677.0
HFD1_k127_5982455_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 615.0
HFD1_k127_5982455_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 596.0
HFD1_k127_5982455_5 GvpD gas vesicle protein K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 554.0
HFD1_k127_5982455_6 X-Pro dipeptidyl-peptidase (S15 family) K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 448.0
HFD1_k127_5982455_7 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 332.0
HFD1_k127_5982455_8 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 318.0
HFD1_k127_5982455_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 306.0
HFD1_k127_5986859_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein K01322,K01354 - 3.4.21.26,3.4.21.83 2.62e-251 794.0
HFD1_k127_5986859_1 Protein tyrosine kinase - - - 2.538e-214 696.0
HFD1_k127_5986859_10 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000009651 52.0
HFD1_k127_5986859_2 Oxidoreductase, molybdopterin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 291.0
HFD1_k127_5986859_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007687 298.0
HFD1_k127_5986859_4 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000000004839 200.0
HFD1_k127_5986859_5 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000732 196.0
HFD1_k127_5986859_6 Cupin domain - - - 0.000000000000000000000000000000000000000000008762 167.0
HFD1_k127_5986859_7 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000005767 72.0
HFD1_k127_5986859_8 Transglycosylase SLT domain K08307 - - 0.00000000003253 73.0
HFD1_k127_6018847_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 1.827e-229 722.0
HFD1_k127_6018847_1 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 366.0
HFD1_k127_6018847_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 346.0
HFD1_k127_6029912_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.536e-266 832.0
HFD1_k127_6029912_1 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 605.0
HFD1_k127_6029912_10 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000473 96.0
HFD1_k127_6029912_11 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000000000321 93.0
HFD1_k127_6029912_12 mRNA binding K07339 - - 0.000000000000000001357 87.0
HFD1_k127_6029912_13 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.000000000000000004218 84.0
HFD1_k127_6029912_15 - - - - 0.000000000000687 76.0
HFD1_k127_6029912_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 567.0
HFD1_k127_6029912_3 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009066 236.0
HFD1_k127_6029912_4 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000005729 219.0
HFD1_k127_6029912_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000005894 164.0
HFD1_k127_6029912_6 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000001886 115.0
HFD1_k127_6029912_9 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000008205 98.0
HFD1_k127_6086284_0 Glycosyl hydrolases family 31 - - - 7.264e-218 696.0
HFD1_k127_6086284_1 Pectate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 561.0
HFD1_k127_6086284_2 GDSL-like Lipase/Acylhydrolase K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000001441 256.0
HFD1_k127_6096289_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 604.0
HFD1_k127_6096289_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 522.0
HFD1_k127_6096289_11 Uncharacterised conserved protein (DUF2156) K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000001507 179.0
HFD1_k127_6096289_12 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000007075 166.0
HFD1_k127_6096289_13 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000002065 143.0
HFD1_k127_6096289_14 light absorption K01822 - 5.3.3.1 0.00000000000000000000000000000002458 130.0
HFD1_k127_6096289_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000343 128.0
HFD1_k127_6096289_16 IMP dehydrogenase activity - - - 0.000000000000000000000003969 110.0
HFD1_k127_6096289_17 transglycosylase K08309 - - 0.00000000000000000003655 104.0
HFD1_k127_6096289_18 - - - - 0.0000000000000000001205 100.0
HFD1_k127_6096289_19 - - - - 0.0000000000000004583 89.0
HFD1_k127_6096289_2 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 467.0
HFD1_k127_6096289_20 Tellurite resistance protein TehB - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.000000000009117 74.0
HFD1_k127_6096289_21 multi-organism process - - - 0.00000000003277 76.0
HFD1_k127_6096289_22 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000006675 66.0
HFD1_k127_6096289_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 374.0
HFD1_k127_6096289_4 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 376.0
HFD1_k127_6096289_5 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 329.0
HFD1_k127_6096289_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 316.0
HFD1_k127_6096289_7 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 301.0
HFD1_k127_6096289_8 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007524 250.0
HFD1_k127_6096289_9 Ndr family - - - 0.00000000000000000000000000000000000000000000000000000000000000006657 234.0
HFD1_k127_6105535_0 PFAM NHL repeat - - - 4.031e-200 644.0
HFD1_k127_6105535_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 467.0
HFD1_k127_6105535_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000002258 150.0
HFD1_k127_6105535_11 RNA recognition motif - - - 0.000000000000000000000000000000002035 133.0
HFD1_k127_6105535_12 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000005036 140.0
HFD1_k127_6105535_13 SMI1-KNR4 cell-wall - - - 0.0000000000000000000000000000000104 134.0
HFD1_k127_6105535_14 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000001554 119.0
HFD1_k127_6105535_15 - - - - 0.00000000000000001828 87.0
HFD1_k127_6105535_16 - - - - 0.0000000000007527 71.0
HFD1_k127_6105535_17 Two component signalling adaptor domain - - - 0.00003236 53.0
HFD1_k127_6105535_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 451.0
HFD1_k127_6105535_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 437.0
HFD1_k127_6105535_4 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 439.0
HFD1_k127_6105535_5 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 408.0
HFD1_k127_6105535_6 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 348.0
HFD1_k127_6105535_7 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 282.0
HFD1_k127_6105535_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001888 246.0
HFD1_k127_6105535_9 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000602 234.0
HFD1_k127_6123595_0 thiolester hydrolase activity - - - 8.124e-208 668.0
HFD1_k127_6123595_1 Ankyrin repeats (many copies) K06015,K06867,K06886 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 358.0
HFD1_k127_6123595_2 PFAM alpha beta hydrolase fold K01259 - 3.4.11.5 0.000000000000000000363 90.0
HFD1_k127_6133167_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 1.228e-306 978.0
HFD1_k127_6133167_1 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 587.0
HFD1_k127_6133167_10 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000002792 72.0
HFD1_k127_6133167_11 SPTR D1C8R1 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000004955 64.0
HFD1_k127_6133167_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 359.0
HFD1_k127_6133167_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 344.0
HFD1_k127_6133167_4 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 298.0
HFD1_k127_6133167_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001297 233.0
HFD1_k127_6133167_6 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000006077 177.0
HFD1_k127_6133167_7 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000001286 154.0
HFD1_k127_6133167_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000002495 139.0
HFD1_k127_6133167_9 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000001926 117.0
HFD1_k127_6136541_0 COG NOG10142 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 515.0
HFD1_k127_6136541_1 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 417.0
HFD1_k127_6136541_2 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 364.0
HFD1_k127_6136541_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002138 249.0
HFD1_k127_6136541_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000162 170.0
HFD1_k127_6136541_5 PFAM amidohydrolase - - - 0.0000000000002595 70.0
HFD1_k127_61976_0 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000002402 119.0
HFD1_k127_6251_0 AAA ATPase domain - - - 5.813e-314 1003.0
HFD1_k127_6251_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 367.0
HFD1_k127_6251_2 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 314.0
HFD1_k127_6251_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 285.0
HFD1_k127_6251_5 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000007295 261.0
HFD1_k127_6251_6 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000001263 104.0
HFD1_k127_6251_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000003169 75.0
HFD1_k127_6251_8 - - - - 0.0003083 51.0
HFD1_k127_62739_0 Alpha-2-Macroglobulin K06894 - - 4.866e-301 981.0
HFD1_k127_62739_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 417.0
HFD1_k127_62739_10 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000003073 171.0
HFD1_k127_62739_11 oxidoreductase activity K07114,K12511 - - 0.00000000000000000000004853 111.0
HFD1_k127_62739_12 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000000000000005387 97.0
HFD1_k127_62739_13 PFAM penicillin-binding protein transpeptidase - - - 0.000000000000000000003091 110.0
HFD1_k127_62739_15 TonB-dependent receptor - - - 0.00000308 57.0
HFD1_k127_62739_2 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 427.0
HFD1_k127_62739_3 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 351.0
HFD1_k127_62739_4 Belongs to the ABC transporter superfamily K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002283 272.0
HFD1_k127_62739_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000001459 227.0
HFD1_k127_62739_6 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000006334 213.0
HFD1_k127_62739_7 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000004137 203.0
HFD1_k127_62739_8 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000002368 212.0
HFD1_k127_62739_9 Protein of unknown function (DUF1175) K09934 - - 0.000000000000000000000000000000000000000000000000002285 193.0
HFD1_k127_630809_0 metallocarboxypeptidase activity K14054 - - 2.34e-281 896.0
HFD1_k127_630809_1 transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 419.0
HFD1_k127_630809_2 Belongs to the bacterial histone-like protein family K03530 - - 0.00000000000000000002074 91.0
HFD1_k127_6320516_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 445.0
HFD1_k127_6320516_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001572 293.0
HFD1_k127_6320516_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000001114 220.0
HFD1_k127_6361381_0 Tricorn protease homolog - - - 0.0 1275.0
HFD1_k127_6361381_1 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1172.0
HFD1_k127_6361381_10 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 353.0
HFD1_k127_6361381_11 Rnd family efflux transporter mfp subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 329.0
HFD1_k127_6361381_12 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002595 274.0
HFD1_k127_6361381_13 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001199 265.0
HFD1_k127_6361381_14 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000264 263.0
HFD1_k127_6361381_15 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000007433 241.0
HFD1_k127_6361381_16 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000002537 218.0
HFD1_k127_6361381_17 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000001398 189.0
HFD1_k127_6361381_18 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000001606 158.0
HFD1_k127_6361381_19 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000001526 142.0
HFD1_k127_6361381_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 4.917e-293 918.0
HFD1_k127_6361381_20 - - - - 0.0000000000000000000000000000000001085 139.0
HFD1_k127_6361381_21 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000001131 139.0
HFD1_k127_6361381_22 Universal stress protein family - - - 0.0000000000000000000000000009153 118.0
HFD1_k127_6361381_23 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000005133 116.0
HFD1_k127_6361381_24 Universal stress protein family - - - 0.00000000000000000000000009078 118.0
HFD1_k127_6361381_25 Protein of unknown function (DUF3788) - - - 0.00000000000000000001858 96.0
HFD1_k127_6361381_26 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000001881 99.0
HFD1_k127_6361381_27 Family of unknown function (DUF5335) - - - 0.00000001377 61.0
HFD1_k127_6361381_28 peptidase activity - - - 0.00000005841 56.0
HFD1_k127_6361381_29 Domain of Unknown Function (DUF928) - - - 0.000001068 59.0
HFD1_k127_6361381_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.104e-243 763.0
HFD1_k127_6361381_30 Membrane - - - 0.0001034 52.0
HFD1_k127_6361381_4 Polyphosphate kinase 2 (PPK2) - - - 1.723e-216 682.0
HFD1_k127_6361381_5 Pyruvate kinase K00873 - 2.7.1.40 9.065e-202 646.0
HFD1_k127_6361381_6 ABC1 family K03688 - - 4.045e-198 632.0
HFD1_k127_6361381_7 Erythromycin esterase - - - 1.464e-197 628.0
HFD1_k127_6361381_8 (ABC) transporter K06147,K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 595.0
HFD1_k127_6361381_9 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 517.0
HFD1_k127_6371407_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 9.013e-198 625.0
HFD1_k127_6371407_1 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 579.0
HFD1_k127_6371407_10 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000007308 202.0
HFD1_k127_6371407_11 ARD/ARD' family - - - 0.00000000000000000000000000000000005827 136.0
HFD1_k127_6371407_12 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000179 103.0
HFD1_k127_6371407_13 Glutathione peroxidase K02199 - - 0.00000000000000000008847 101.0
HFD1_k127_6371407_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 481.0
HFD1_k127_6371407_3 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 449.0
HFD1_k127_6371407_4 cell redox homeostasis K00384,K12057,K12267,K21636 - 1.1.98.6,1.8.1.9,1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 375.0
HFD1_k127_6371407_5 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000004962 262.0
HFD1_k127_6371407_6 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006917 264.0
HFD1_k127_6371407_7 DinB family - - - 0.000000000000000000000000000000000000000000000000000002582 194.0
HFD1_k127_6371407_8 - - - - 0.000000000000000000000000000000000000000000000000003627 195.0
HFD1_k127_6371407_9 EamA-like transporter family K07790 - - 0.0000000000000000000000000000000000000000000000002373 187.0
HFD1_k127_6445848_0 alpha-L-rhamnosidase - - - 0.0 1485.0
HFD1_k127_6445848_1 Protein kinase domain K12132 - 2.7.11.1 1.004e-246 793.0
HFD1_k127_6445848_10 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 347.0
HFD1_k127_6445848_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 314.0
HFD1_k127_6445848_12 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 314.0
HFD1_k127_6445848_13 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 315.0
HFD1_k127_6445848_14 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009072 251.0
HFD1_k127_6445848_15 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000001326 234.0
HFD1_k127_6445848_16 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000001114 220.0
HFD1_k127_6445848_17 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000145 212.0
HFD1_k127_6445848_18 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.000000000000000000000000000000000000000000000000000000005363 204.0
HFD1_k127_6445848_19 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000508 181.0
HFD1_k127_6445848_2 alpha beta - - - 1.57e-215 677.0
HFD1_k127_6445848_20 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000002516 173.0
HFD1_k127_6445848_21 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000797 176.0
HFD1_k127_6445848_22 Haem-degrading - - - 0.0000000000000000000000000000000000000628 147.0
HFD1_k127_6445848_23 - - - - 0.0000000000000000000000000001561 121.0
HFD1_k127_6445848_24 peptidyl-arginine hydroxylation - - - 0.00000000000000000000000003917 119.0
HFD1_k127_6445848_25 Protein of unknown function (DUF3455) - - - 0.000000000000000000000004745 111.0
HFD1_k127_6445848_26 VIT family - - - 0.00000000000000000001288 94.0
HFD1_k127_6445848_27 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.000000000000000001002 86.0
HFD1_k127_6445848_28 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000002148 90.0
HFD1_k127_6445848_29 Tetratricopeptide repeats K08282,K12132 - 2.7.11.1 0.00000004449 59.0
HFD1_k127_6445848_3 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 604.0
HFD1_k127_6445848_30 Putative zinc-finger - - - 0.00003748 50.0
HFD1_k127_6445848_31 Putative zinc-finger - - - 0.00008661 49.0
HFD1_k127_6445848_32 Galactose oxidase, central domain - - - 0.0001123 48.0
HFD1_k127_6445848_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 586.0
HFD1_k127_6445848_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 524.0
HFD1_k127_6445848_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 522.0
HFD1_k127_6445848_7 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 409.0
HFD1_k127_6445848_8 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 368.0
HFD1_k127_6445848_9 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 340.0
HFD1_k127_6474103_0 PfkB domain protein K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 576.0
HFD1_k127_6474103_1 transmembrane transporter activity K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 557.0
HFD1_k127_6474103_2 PFAM Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 342.0
HFD1_k127_6474103_3 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007559 274.0
HFD1_k127_6474103_4 oxalate decarboxylase activity K11312 - - 0.00000000000000003537 89.0
HFD1_k127_6474103_5 Gluconokinase K00851 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0046316 2.7.1.12 0.000000000001419 70.0
HFD1_k127_6480809_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 525.0
HFD1_k127_6480809_1 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000231 293.0
HFD1_k127_6480809_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000006553 251.0
HFD1_k127_6480809_3 nudix family K01515 - 3.6.1.13 0.000000000000000000000000000000000000127 148.0
HFD1_k127_6480809_4 Belongs to the UPF0102 family K07460 - - 0.00000000000002566 80.0
HFD1_k127_6480809_5 30S ribosomal protein Thx K19033 - - 0.00002085 49.0
HFD1_k127_6493242_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001369 224.0
HFD1_k127_6501523_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1240.0
HFD1_k127_6501523_1 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 1.747e-303 945.0
HFD1_k127_6501523_10 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000001827 165.0
HFD1_k127_6501523_11 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000003489 160.0
HFD1_k127_6501523_12 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000006685 160.0
HFD1_k127_6501523_13 Rossmann-like domain - - - 0.0000000000000000000000000000000001479 145.0
HFD1_k127_6501523_14 Thioredoxin-like - - - 0.00000000000000000000000000000008157 132.0
HFD1_k127_6501523_15 zinc ion binding K06204 - - 0.000000000008134 70.0
HFD1_k127_6501523_16 Histidine kinase - - - 0.0000000001607 66.0
HFD1_k127_6501523_17 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000001056 53.0
HFD1_k127_6501523_18 - - - - 0.000001025 56.0
HFD1_k127_6501523_19 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0002171 48.0
HFD1_k127_6501523_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.202e-213 681.0
HFD1_k127_6501523_3 radical SAM domain protein - - - 1.639e-194 619.0
HFD1_k127_6501523_4 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 546.0
HFD1_k127_6501523_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 327.0
HFD1_k127_6501523_6 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000543 261.0
HFD1_k127_6501523_7 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001897 266.0
HFD1_k127_6501523_8 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005658 256.0
HFD1_k127_6501523_9 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000008479 213.0
HFD1_k127_6515463_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.912e-312 976.0
HFD1_k127_6515463_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 1.252e-299 932.0
HFD1_k127_6515463_10 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 372.0
HFD1_k127_6515463_11 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 344.0
HFD1_k127_6515463_12 TIGRFAM parallel beta-helix repeat (two copies) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 337.0
HFD1_k127_6515463_13 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 307.0
HFD1_k127_6515463_14 CRP FNR family - - - 0.00000000000000000000000000000000000000000000000000000000000003918 222.0
HFD1_k127_6515463_15 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
HFD1_k127_6515463_16 - - - - 0.0000000000000000000000000000000000000000000000000000000001394 209.0
HFD1_k127_6515463_17 YwiC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000006516 211.0
HFD1_k127_6515463_18 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000002385 203.0
HFD1_k127_6515463_19 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000008649 205.0
HFD1_k127_6515463_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.849e-256 797.0
HFD1_k127_6515463_20 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000003368 184.0
HFD1_k127_6515463_21 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000004101 169.0
HFD1_k127_6515463_22 COG1131 ABC-type multidrug transport system, ATPase component K01990,K19340 - - 0.0000000000000000000000000000000000000000001658 171.0
HFD1_k127_6515463_23 - - - - 0.00000000000000000000000000000000000001341 150.0
HFD1_k127_6515463_24 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000001788 143.0
HFD1_k127_6515463_25 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000001772 142.0
HFD1_k127_6515463_26 RNA recognition motif - - - 0.000000000000000000000000000000007978 130.0
HFD1_k127_6515463_27 - - - - 0.0000000000000000000000000000001145 143.0
HFD1_k127_6515463_28 Capsular exopolysaccharide family K16554,K16692 - - 0.000000000000000000000000000007703 135.0
HFD1_k127_6515463_29 O-Antigen ligase K02847 - - 0.0000000000000000000000000006159 130.0
HFD1_k127_6515463_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 9.588e-245 772.0
HFD1_k127_6515463_30 AAA ATPase domain - - - 0.000000000000000000000000001825 126.0
HFD1_k127_6515463_31 Tetratricopeptide repeat - - - 0.0000000000000000000000000804 117.0
HFD1_k127_6515463_32 NosL K19342 - - 0.000000000000000000000001919 109.0
HFD1_k127_6515463_33 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000006456 102.0
HFD1_k127_6515463_35 Domain of unknown function DUF302 - - - 0.00000000000005711 74.0
HFD1_k127_6515463_37 Cro/C1-type HTH DNA-binding domain - - - 0.00000000008665 66.0
HFD1_k127_6515463_38 Hemerythrin HHE cation binding domain - - - 0.00000000012 70.0
HFD1_k127_6515463_39 CAAX protease self-immunity K07052 - - 0.000000000125 71.0
HFD1_k127_6515463_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 560.0
HFD1_k127_6515463_40 Periplasmic or secreted lipoprotein - - - 0.00000003831 66.0
HFD1_k127_6515463_41 - - - - 0.0000009923 55.0
HFD1_k127_6515463_42 COG0457 FOG TPR repeat - - - 0.000002074 60.0
HFD1_k127_6515463_5 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 547.0
HFD1_k127_6515463_6 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 530.0
HFD1_k127_6515463_7 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 461.0
HFD1_k127_6515463_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 430.0
HFD1_k127_6515463_9 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 389.0
HFD1_k127_6518868_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.921e-287 893.0
HFD1_k127_6518868_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.654e-271 858.0
HFD1_k127_6518868_10 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000001962 103.0
HFD1_k127_6518868_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000001865 94.0
HFD1_k127_6518868_13 Cytochrome c K00406,K08906 - - 0.0000000001 67.0
HFD1_k127_6518868_14 iron ion homeostasis - - - 0.0001448 54.0
HFD1_k127_6518868_2 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.035e-216 683.0
HFD1_k127_6518868_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 610.0
HFD1_k127_6518868_4 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 569.0
HFD1_k127_6518868_5 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 320.0
HFD1_k127_6518868_6 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 309.0
HFD1_k127_6518868_7 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006752 293.0
HFD1_k127_6518868_8 Oxidoreductase NAD-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003569 285.0
HFD1_k127_6518868_9 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000004816 106.0
HFD1_k127_6519113_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.343e-300 935.0
HFD1_k127_6519113_1 amine dehydrogenase activity - - - 2.778e-200 638.0
HFD1_k127_6519113_10 Tetratricopeptide repeat K02200 - - 0.0000000000000000000000000000000000000000000000000000368 198.0
HFD1_k127_6519113_11 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000004589 168.0
HFD1_k127_6519113_13 - - - - 0.000000000000000003447 90.0
HFD1_k127_6519113_14 Protein of unknown function (DUF1059) - - - 0.000000000000004898 81.0
HFD1_k127_6519113_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000004838 70.0
HFD1_k127_6519113_16 SNARE associated Golgi protein - - - 0.00000000001252 71.0
HFD1_k127_6519113_17 Tetratricopeptide TPR_2 repeat protein - - - 0.00007303 52.0
HFD1_k127_6519113_2 TIGRFAM magnesium chelatase, H subunit K03403 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 475.0
HFD1_k127_6519113_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 346.0
HFD1_k127_6519113_4 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 297.0
HFD1_k127_6519113_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 282.0
HFD1_k127_6519113_6 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000001383 238.0
HFD1_k127_6519113_7 Periplasmic protein thiol K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000003134 233.0
HFD1_k127_6519113_8 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000002013 218.0
HFD1_k127_6519113_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000003006 206.0
HFD1_k127_6525260_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.983e-285 891.0
HFD1_k127_6525260_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 416.0
HFD1_k127_6525260_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000001786 87.0
HFD1_k127_6525260_11 domain protein K14194 - - 0.000000000000002626 90.0
HFD1_k127_6525260_12 NUDIX domain - - - 0.00000000002045 71.0
HFD1_k127_6525260_14 peptidyl-tyrosine sulfation - - - 0.00000002658 64.0
HFD1_k127_6525260_15 Carboxypeptidase regulatory-like domain - - - 0.000008466 59.0
HFD1_k127_6525260_2 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 391.0
HFD1_k127_6525260_3 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 326.0
HFD1_k127_6525260_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006878 293.0
HFD1_k127_6525260_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000002349 224.0
HFD1_k127_6525260_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
HFD1_k127_6525260_7 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000001318 211.0
HFD1_k127_6525260_8 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000101 208.0
HFD1_k127_6525260_9 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000002773 166.0
HFD1_k127_6539261_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 411.0
HFD1_k127_6539261_1 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 297.0
HFD1_k127_6539261_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000002135 190.0
HFD1_k127_6539261_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000004009 74.0
HFD1_k127_6647805_0 PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal K01621 GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 0.0 1399.0
HFD1_k127_6647805_1 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1274.0
HFD1_k127_6647805_10 cystathionine gamma-synthase activity K01739,K01740,K01760,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 592.0
HFD1_k127_6647805_11 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 527.0
HFD1_k127_6647805_12 Asparaginase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 521.0
HFD1_k127_6647805_13 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 523.0
HFD1_k127_6647805_14 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 511.0
HFD1_k127_6647805_15 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 504.0
HFD1_k127_6647805_16 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 465.0
HFD1_k127_6647805_17 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 467.0
HFD1_k127_6647805_18 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 453.0
HFD1_k127_6647805_19 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 484.0
HFD1_k127_6647805_2 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1251.0
HFD1_k127_6647805_20 transcription factor binding K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 444.0
HFD1_k127_6647805_21 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 411.0
HFD1_k127_6647805_22 anaerobic c4-dicarboxylate K07791,K07792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 407.0
HFD1_k127_6647805_23 Sodium calcium exchanger membrane K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 400.0
HFD1_k127_6647805_24 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 386.0
HFD1_k127_6647805_25 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 341.0
HFD1_k127_6647805_26 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 348.0
HFD1_k127_6647805_27 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 314.0
HFD1_k127_6647805_28 PFAM CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 314.0
HFD1_k127_6647805_29 Possible lysine decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 291.0
HFD1_k127_6647805_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 9.879e-276 863.0
HFD1_k127_6647805_30 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 297.0
HFD1_k127_6647805_31 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001712 291.0
HFD1_k127_6647805_32 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001531 253.0
HFD1_k127_6647805_33 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001568 244.0
HFD1_k127_6647805_34 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000002619 235.0
HFD1_k127_6647805_35 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001838 232.0
HFD1_k127_6647805_36 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000001439 220.0
HFD1_k127_6647805_37 - - - - 0.000000000000000000000000000000000000000000000000000000002048 210.0
HFD1_k127_6647805_38 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000001141 199.0
HFD1_k127_6647805_39 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000004666 201.0
HFD1_k127_6647805_4 serine dehydratase beta chain K01752 - 4.3.1.17 9.025e-272 845.0
HFD1_k127_6647805_40 - - - - 0.00000000000000000000000000000000000000000000002497 180.0
HFD1_k127_6647805_41 Haem-binding domain - - - 0.000000000000000000000000000000000000279 145.0
HFD1_k127_6647805_42 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000001578 144.0
HFD1_k127_6647805_43 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.000000000000000000000000000000003087 141.0
HFD1_k127_6647805_44 response regulator K02282 - - 0.0000000000000000000000000000001797 128.0
HFD1_k127_6647805_45 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.000000000000000000000000000000191 130.0
HFD1_k127_6647805_46 - - - - 0.00000000000000000000000001012 113.0
HFD1_k127_6647805_47 Protein of unknown function (DUF2950) - - - 0.00000000000000000000004746 99.0
HFD1_k127_6647805_48 Ion channel - - - 0.00000000000000000000009056 104.0
HFD1_k127_6647805_49 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000005727 93.0
HFD1_k127_6647805_5 Carboxypeptidase regulatory-like domain - - - 8.017e-267 855.0
HFD1_k127_6647805_50 Domain of unknown function (DUF4136) - - - 0.000000000000001626 83.0
HFD1_k127_6647805_51 Antibiotic biosynthesis monooxygenase - GO:0003674,GO:0003824 - 0.0000003711 57.0
HFD1_k127_6647805_52 general secretion pathway protein K02456 - - 0.00001112 54.0
HFD1_k127_6647805_53 HEAT repeat - - - 0.00001305 58.0
HFD1_k127_6647805_54 repeat-containing protein K22221 - - 0.00001783 57.0
HFD1_k127_6647805_55 Non-ribosomal peptide synthase - - - 0.00006005 56.0
HFD1_k127_6647805_6 Fumarase C C-terminus - - - 4.482e-249 775.0
HFD1_k127_6647805_7 Sulfate permease family - - - 5.812e-241 757.0
HFD1_k127_6647805_8 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 1.04e-216 685.0
HFD1_k127_6647805_9 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 2.527e-202 635.0
HFD1_k127_6676608_0 MMPL family K03296 - - 0.0 1223.0
HFD1_k127_6676608_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1214.0
HFD1_k127_6676608_10 PFAM cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 454.0
HFD1_k127_6676608_11 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 454.0
HFD1_k127_6676608_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 350.0
HFD1_k127_6676608_13 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 350.0
HFD1_k127_6676608_14 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
HFD1_k127_6676608_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 327.0
HFD1_k127_6676608_16 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001234 271.0
HFD1_k127_6676608_17 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000001938 269.0
HFD1_k127_6676608_18 Glycosyl hydrolases family 25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000933 244.0
HFD1_k127_6676608_19 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000002495 243.0
HFD1_k127_6676608_2 serine-type peptidase activity - - - 0.0 1060.0
HFD1_k127_6676608_20 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000004838 240.0
HFD1_k127_6676608_21 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000005345 223.0
HFD1_k127_6676608_22 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001222 222.0
HFD1_k127_6676608_23 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000002442 209.0
HFD1_k127_6676608_24 transferase activity, transferring acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000843 201.0
HFD1_k127_6676608_25 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000001715 203.0
HFD1_k127_6676608_26 Zn-dependent hydrolase, glyoxylase - - - 0.0000000000000000000000000000000000000000000000000001171 198.0
HFD1_k127_6676608_27 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000002927 184.0
HFD1_k127_6676608_28 lipopolysaccharide transport K09774 - - 0.0000000000000000000000000000000000000000000001546 192.0
HFD1_k127_6676608_29 - - - - 0.0000000000000000000000000000000000000000004477 180.0
HFD1_k127_6676608_3 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 2.473e-270 854.0
HFD1_k127_6676608_30 Transcriptional repressor, CopY family - - - 0.0000000000000000000000000000000000000001378 154.0
HFD1_k127_6676608_31 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000001463 143.0
HFD1_k127_6676608_32 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000001501 141.0
HFD1_k127_6676608_33 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000005656 127.0
HFD1_k127_6676608_34 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000007925 108.0
HFD1_k127_6676608_35 YjbR - - - 0.00000000000000000000005335 106.0
HFD1_k127_6676608_36 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000006122 93.0
HFD1_k127_6676608_37 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000008603 70.0
HFD1_k127_6676608_4 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 1.792e-196 630.0
HFD1_k127_6676608_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 574.0
HFD1_k127_6676608_6 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 534.0
HFD1_k127_6676608_7 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 509.0
HFD1_k127_6676608_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 486.0
HFD1_k127_6676608_9 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 469.0
HFD1_k127_6691262_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1151.0
HFD1_k127_6691262_1 Carboxypeptidase regulatory-like domain - - - 0.0 1032.0
HFD1_k127_6691262_10 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 485.0
HFD1_k127_6691262_11 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 474.0
HFD1_k127_6691262_12 Periplasmic protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 461.0
HFD1_k127_6691262_13 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 446.0
HFD1_k127_6691262_14 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 439.0
HFD1_k127_6691262_15 UDP-N-acetylglucosamine 2-epimerase K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 437.0
HFD1_k127_6691262_16 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 439.0
HFD1_k127_6691262_17 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 436.0
HFD1_k127_6691262_18 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 428.0
HFD1_k127_6691262_19 oxidoreductase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009342 411.0
HFD1_k127_6691262_2 Carboxypeptidase regulatory-like domain - - - 8.095e-311 991.0
HFD1_k127_6691262_20 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 422.0
HFD1_k127_6691262_21 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 389.0
HFD1_k127_6691262_22 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 383.0
HFD1_k127_6691262_23 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 342.0
HFD1_k127_6691262_24 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 335.0
HFD1_k127_6691262_25 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 314.0
HFD1_k127_6691262_26 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 321.0
HFD1_k127_6691262_27 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 312.0
HFD1_k127_6691262_28 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 317.0
HFD1_k127_6691262_29 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
HFD1_k127_6691262_3 nodulation K00612 - - 2.72e-270 846.0
HFD1_k127_6691262_30 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 301.0
HFD1_k127_6691262_31 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 286.0
HFD1_k127_6691262_32 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003211 287.0
HFD1_k127_6691262_33 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000005227 252.0
HFD1_k127_6691262_34 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000002967 269.0
HFD1_k127_6691262_35 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000925 249.0
HFD1_k127_6691262_36 Pfam Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000002306 235.0
HFD1_k127_6691262_37 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000244 229.0
HFD1_k127_6691262_38 O-acyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000007567 220.0
HFD1_k127_6691262_39 peptidoglycan biosynthetic process K03980,K21004 - - 0.00000000000000000000000000000000000000000000000000000000000001158 232.0
HFD1_k127_6691262_4 Asparagine synthase K01953 - 6.3.5.4 1.277e-243 767.0
HFD1_k127_6691262_40 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000002651 211.0
HFD1_k127_6691262_41 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000002734 214.0
HFD1_k127_6691262_42 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000001556 213.0
HFD1_k127_6691262_43 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.0000000000000000000000000000000000000000000000000000002447 207.0
HFD1_k127_6691262_44 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.0000000000000000000000000000000000000000000000000003109 191.0
HFD1_k127_6691262_45 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000001732 197.0
HFD1_k127_6691262_46 - - - - 0.000000000000000000000000000000000000000000000000003707 190.0
HFD1_k127_6691262_47 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.000000000000000000000000000000000000000000000000004151 190.0
HFD1_k127_6691262_48 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000005713 188.0
HFD1_k127_6691262_49 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000001344 191.0
HFD1_k127_6691262_5 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 626.0
HFD1_k127_6691262_50 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000001385 184.0
HFD1_k127_6691262_51 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.00000000000000000000000000000000000000000000001263 179.0
HFD1_k127_6691262_52 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000002452 183.0
HFD1_k127_6691262_53 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000005313 183.0
HFD1_k127_6691262_55 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000000001676 175.0
HFD1_k127_6691262_56 polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000001977 164.0
HFD1_k127_6691262_57 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000002426 143.0
HFD1_k127_6691262_59 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000003503 145.0
HFD1_k127_6691262_6 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 559.0
HFD1_k127_6691262_60 SnoaL-like domain - - - 0.00000000000000000000000000000002331 130.0
HFD1_k127_6691262_61 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000005056 136.0
HFD1_k127_6691262_62 oxidoreductase - - - 0.00000000000000000000000000004194 129.0
HFD1_k127_6691262_63 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000004244 119.0
HFD1_k127_6691262_64 hydroperoxide reductase activity - - - 0.0000000000000000000005678 98.0
HFD1_k127_6691262_65 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000004459 107.0
HFD1_k127_6691262_66 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000001657 100.0
HFD1_k127_6691262_67 PFAM CHAD domain containing protein - - - 0.000000000000000001267 97.0
HFD1_k127_6691262_68 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000001331 97.0
HFD1_k127_6691262_69 - - - - 0.0000000000000003944 83.0
HFD1_k127_6691262_7 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 538.0
HFD1_k127_6691262_70 - - - - 0.00000000000001146 74.0
HFD1_k127_6691262_71 Aldo/keto reductase family - - - 0.0000000000001056 72.0
HFD1_k127_6691262_72 resistance protein K15725 - - 0.0000000000002763 83.0
HFD1_k127_6691262_73 - - - - 0.0000000000007102 81.0
HFD1_k127_6691262_76 Methyltransferase domain - - - 0.00000003956 64.0
HFD1_k127_6691262_78 - - - - 0.00002914 51.0
HFD1_k127_6691262_79 YtkA-like - - - 0.00006702 52.0
HFD1_k127_6691262_8 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 508.0
HFD1_k127_6691262_80 homolog subfamily C member K09523 GO:0000323,GO:0001775,GO:0001932,GO:0001933,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0004857,GO:0004860,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0005790,GO:0005829,GO:0006417,GO:0006446,GO:0006464,GO:0006469,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006986,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010563,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010941,GO:0012505,GO:0016192,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0023052,GO:0030141,GO:0030163,GO:0030234,GO:0030968,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031400,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032056,GO:0032058,GO:0032268,GO:0032269,GO:0032270,GO:0032940,GO:0033554,GO:0033673,GO:0034248,GO:0034250,GO:0034620,GO:0034774,GO:0034976,GO:0035578,GO:0035966,GO:0035967,GO:0036211,GO:0036230,GO:0036490,GO:0036491,GO:0036493,GO:0036494,GO:0036498,GO:0042119,GO:0042221,GO:0042325,GO:0042326,GO:0042582,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043549,GO:0043555,GO:0043558,GO:0043687,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045727,GO:0045859,GO:0045936,GO:0045948,GO:0046903,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051087,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051338,GO:0051348,GO:0051603,GO:0051716,GO:0051787,GO:0060205,GO:0060255,GO:0060548,GO:0065007,GO:0065009,GO:0070013,GO:0070417,GO:0070887,GO:0071310,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0097708,GO:0098772,GO:0099503,GO:1901564,GO:1901565,GO:1901575,GO:1903573,GO:1903912,GO:1905897,GO:2000112 - 0.0001529 54.0
HFD1_k127_6691262_9 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 488.0
HFD1_k127_672748_0 von Willebrand factor, type A K07114 - - 2.882e-221 705.0
HFD1_k127_672748_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 542.0
HFD1_k127_672748_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 368.0
HFD1_k127_672748_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003345 272.0
HFD1_k127_672748_4 - - - - 0.0000000000000000000000000008701 126.0
HFD1_k127_672748_5 Protein tyrosine kinase - - - 0.0000000000007826 70.0
HFD1_k127_672748_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000008865 73.0
HFD1_k127_672748_7 Helix-turn-helix domain - - - 0.00000001276 63.0
HFD1_k127_672748_8 Protein kinase domain K12132 - 2.7.11.1 0.00003119 51.0
HFD1_k127_672748_9 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0007193 49.0
HFD1_k127_673489_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 590.0
HFD1_k127_673489_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 454.0
HFD1_k127_673489_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000001392 154.0
HFD1_k127_673489_11 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000007535 129.0
HFD1_k127_673489_12 ThiS family K03636 - - 0.00000000006077 68.0
HFD1_k127_673489_2 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 424.0
HFD1_k127_673489_3 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 366.0
HFD1_k127_673489_4 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 353.0
HFD1_k127_673489_5 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 317.0
HFD1_k127_673489_6 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 305.0
HFD1_k127_673489_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001712 225.0
HFD1_k127_673489_8 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000001896 220.0
HFD1_k127_673489_9 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000001007 170.0
HFD1_k127_67791_0 cellulose binding - - - 1.135e-292 931.0
HFD1_k127_67791_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 8.27e-224 719.0
HFD1_k127_67791_10 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 309.0
HFD1_k127_67791_11 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 299.0
HFD1_k127_67791_12 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 301.0
HFD1_k127_67791_13 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 290.0
HFD1_k127_67791_14 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006965 276.0
HFD1_k127_67791_15 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004249 280.0
HFD1_k127_67791_16 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000007605 250.0
HFD1_k127_67791_17 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001 240.0
HFD1_k127_67791_18 Protein tyrosine kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000001887 264.0
HFD1_k127_67791_19 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000005551 219.0
HFD1_k127_67791_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.382e-220 703.0
HFD1_k127_67791_20 Participates in transcription elongation, termination and antitermination - - - 0.000000000000000000000000000000000000000000000000003854 198.0
HFD1_k127_67791_21 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000005196 203.0
HFD1_k127_67791_22 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000009306 175.0
HFD1_k127_67791_23 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000003884 164.0
HFD1_k127_67791_24 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000002005 159.0
HFD1_k127_67791_25 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000001481 142.0
HFD1_k127_67791_26 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000005046 128.0
HFD1_k127_67791_27 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000002932 125.0
HFD1_k127_67791_28 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000001301 120.0
HFD1_k127_67791_29 - - - - 0.000000000000000000000000003689 118.0
HFD1_k127_67791_3 PFAM Type II secretion system protein E K02652 - - 7.925e-219 692.0
HFD1_k127_67791_30 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000431 116.0
HFD1_k127_67791_31 type II and III secretion system protein K02453 - - 0.00000000000000000000004504 117.0
HFD1_k127_67791_32 Thioredoxin-like - - - 0.000000000000000000004004 101.0
HFD1_k127_67791_33 - - - - 0.00000000000000000001244 100.0
HFD1_k127_67791_34 - - - - 0.0000000000000000002572 87.0
HFD1_k127_67791_35 Cupin domain - - - 0.000000000000005557 78.0
HFD1_k127_67791_36 3D domain protein - - - 0.00000000000002712 81.0
HFD1_k127_67791_37 - - - - 0.000000000001633 72.0
HFD1_k127_67791_38 SnoaL-like domain - - - 0.000000004182 65.0
HFD1_k127_67791_39 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000002065 65.0
HFD1_k127_67791_4 Amino acid permease K03294 - - 2.249e-215 679.0
HFD1_k127_67791_5 Carboxypeptidase regulatory-like domain - - - 4.635e-202 667.0
HFD1_k127_67791_6 DNA polymerase K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 497.0
HFD1_k127_67791_7 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 456.0
HFD1_k127_67791_8 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 421.0
HFD1_k127_67791_9 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 382.0
HFD1_k127_6811730_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 2.572e-221 695.0
HFD1_k127_6811730_1 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 484.0
HFD1_k127_6811730_10 acetyltransferase - - - 0.0000000000000000000000000001101 119.0
HFD1_k127_6811730_11 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000001188 118.0
HFD1_k127_6811730_12 isomerase activity K01821 - 5.3.2.6 0.0000000000000000000001867 98.0
HFD1_k127_6811730_13 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000002431 100.0
HFD1_k127_6811730_14 - - - - 0.000000000002695 69.0
HFD1_k127_6811730_15 repeat-containing protein - - - 0.000000000003869 79.0
HFD1_k127_6811730_16 Virulence factor BrkB K07058 - - 0.0000000004938 63.0
HFD1_k127_6811730_17 bacterial OsmY and nodulation domain K04065 - - 0.00000001109 63.0
HFD1_k127_6811730_18 Transglutaminase-like superfamily - - - 0.000003223 60.0
HFD1_k127_6811730_19 CsbD-like - - - 0.00001248 50.0
HFD1_k127_6811730_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 417.0
HFD1_k127_6811730_3 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001204 243.0
HFD1_k127_6811730_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000481 233.0
HFD1_k127_6811730_5 - - - - 0.00000000000000000000000000000000000000000000000000000000001076 212.0
HFD1_k127_6811730_6 PFAM penicillin-binding protein transpeptidase - - - 0.00000000000000000000000000000000000000000000000000000004825 217.0
HFD1_k127_6811730_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000287 175.0
HFD1_k127_6811730_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000002933 173.0
HFD1_k127_6811730_9 secondary active sulfate transmembrane transporter activity - - - 0.00000000000000000000000000000000002179 143.0
HFD1_k127_6895196_0 Carboxypeptidase regulatory-like domain - - - 0.0 1461.0
HFD1_k127_6895196_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1318.0
HFD1_k127_6895196_10 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001 261.0
HFD1_k127_6895196_11 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007832 244.0
HFD1_k127_6895196_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001372 225.0
HFD1_k127_6895196_13 PFAM Isochorismatase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000118 198.0
HFD1_k127_6895196_14 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000201 188.0
HFD1_k127_6895196_15 ORF6N domain - - - 0.00000000000000000000000000000000000008225 148.0
HFD1_k127_6895196_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000005563 135.0
HFD1_k127_6895196_17 TonB dependent receptor K02014,K16087 - - 0.0000000000000000000000000000007034 142.0
HFD1_k127_6895196_18 Penicillinase repressor - - - 0.000000000000000000000109 104.0
HFD1_k127_6895196_19 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000007418 89.0
HFD1_k127_6895196_2 cellulose binding - - - 0.0 1184.0
HFD1_k127_6895196_20 PBS lyase HEAT-like repeat - - - 0.00000000000000004555 94.0
HFD1_k127_6895196_21 HEAT repeats - - - 0.0000000000001238 84.0
HFD1_k127_6895196_23 PFAM Major Facilitator Superfamily - - - 0.000003686 51.0
HFD1_k127_6895196_24 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000283 51.0
HFD1_k127_6895196_25 Belongs to the peptidase M48B family - - - 0.000118 53.0
HFD1_k127_6895196_26 Putative zinc-finger - - - 0.0002811 52.0
HFD1_k127_6895196_3 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 615.0
HFD1_k127_6895196_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 414.0
HFD1_k127_6895196_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 344.0
HFD1_k127_6895196_6 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 333.0
HFD1_k127_6895196_7 ABC-type hemin transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 308.0
HFD1_k127_6895196_8 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 330.0
HFD1_k127_6895196_9 abc transporter (atp-binding protein) K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 289.0
HFD1_k127_6936021_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 409.0
HFD1_k127_6936021_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 324.0
HFD1_k127_695154_0 PFAM Cna B domain protein - - - 0.0 1258.0
HFD1_k127_695154_1 PFAM Cna B domain protein - - - 0.0 1217.0
HFD1_k127_695154_2 beta-lactamase - - - 2.367e-255 811.0
HFD1_k127_695154_3 symporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 464.0
HFD1_k127_695154_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 464.0
HFD1_k127_695154_5 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 305.0
HFD1_k127_695154_6 BadF BadG BcrA BcrD - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000009988 169.0
HFD1_k127_695154_7 LysR substrate binding domain - - - 0.000000000000000000000000000000000000007639 157.0
HFD1_k127_695154_8 transport - - - 0.000001086 50.0
HFD1_k127_6990828_0 Putative glucoamylase - - - 1.971e-197 625.0
HFD1_k127_6990828_1 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 409.0
HFD1_k127_6990828_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 334.0
HFD1_k127_6990828_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 315.0
HFD1_k127_6990828_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 303.0
HFD1_k127_6990828_5 PFAM Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000006419 177.0
HFD1_k127_6990828_6 - - - - 0.000000000000000000000000000000000001919 142.0
HFD1_k127_6990828_7 domain protein - - - 0.0000000000000000000000000000000001373 136.0
HFD1_k127_6990828_8 - - - - 0.00002997 47.0
HFD1_k127_7005031_0 PFAM Leukotriene A4 hydrolase, C-terminal - - - 8.483e-220 700.0
HFD1_k127_7005031_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 416.0
HFD1_k127_7005031_2 region 4 type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 264.0
HFD1_k127_7005031_3 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007333 232.0
HFD1_k127_7005031_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004567,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015923,GO:0016052,GO:0016787,GO:0016798,GO:0016985,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0071554,GO:0071704,GO:1901575 3.2.1.78 0.0000000000000000000000000000000000000000000000002273 198.0
HFD1_k127_7005031_5 - - - - 0.0000000000000000000000003438 111.0
HFD1_k127_7005031_6 - - - - 0.00000000000000001962 88.0
HFD1_k127_7005031_7 Domain of unknown function (DUF4386) - - - 0.0000001487 61.0
HFD1_k127_7030641_0 Protein tyrosine kinase - - - 2.086e-224 723.0
HFD1_k127_7030641_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 599.0
HFD1_k127_7030641_10 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000005289 242.0
HFD1_k127_7030641_11 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000005404 217.0
HFD1_k127_7030641_12 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000005166 154.0
HFD1_k127_7030641_13 WD40-like Beta Propeller Repeat - - - 0.00000000000000000001628 92.0
HFD1_k127_7030641_14 Transcriptional regulator - - - 0.000000000000000001652 96.0
HFD1_k127_7030641_15 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 0.0003688 44.0
HFD1_k127_7030641_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 560.0
HFD1_k127_7030641_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 551.0
HFD1_k127_7030641_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 366.0
HFD1_k127_7030641_5 glucosamine-6-phosphate deaminase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 341.0
HFD1_k127_7030641_6 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 310.0
HFD1_k127_7030641_7 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 296.0
HFD1_k127_7030641_8 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000005883 263.0
HFD1_k127_7030641_9 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
HFD1_k127_704714_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 520.0
HFD1_k127_704714_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 477.0
HFD1_k127_704714_10 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000000003032 216.0
HFD1_k127_704714_11 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000329 215.0
HFD1_k127_704714_12 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000004195 214.0
HFD1_k127_704714_13 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000001232 145.0
HFD1_k127_704714_14 - - - - 0.00000000000000000000000000001092 120.0
HFD1_k127_704714_15 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000006043 119.0
HFD1_k127_704714_16 Salmonella virulence plasmid 28.1kDa A protein K07127 GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17 0.0000000000000000000005025 99.0
HFD1_k127_704714_17 multi-organism process K03195 - - 0.000000000000003031 87.0
HFD1_k127_704714_18 PrcB C-terminal - - - 0.000000005269 64.0
HFD1_k127_704714_19 PFAM Integrase catalytic - - - 0.00000004095 58.0
HFD1_k127_704714_20 Helix-turn-helix XRE-family like proteins - - - 0.0000001076 59.0
HFD1_k127_704714_21 cAMP biosynthetic process - - - 0.00002975 49.0
HFD1_k127_704714_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 450.0
HFD1_k127_704714_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 421.0
HFD1_k127_704714_5 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 381.0
HFD1_k127_704714_6 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 366.0
HFD1_k127_704714_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 302.0
HFD1_k127_704714_8 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
HFD1_k127_704714_9 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000008523 242.0
HFD1_k127_7088502_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 628.0
HFD1_k127_7088502_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001823 274.0
HFD1_k127_7088502_2 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000001569 154.0
HFD1_k127_7088502_3 - - - - 0.0000002124 53.0
HFD1_k127_7088502_4 - - - - 0.000001792 50.0
HFD1_k127_7114849_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 0.0 1263.0
HFD1_k127_7114849_1 dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 508.0
HFD1_k127_7114849_10 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000154 50.0
HFD1_k127_7114849_2 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 317.0
HFD1_k127_7114849_3 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004561 250.0
HFD1_k127_7114849_4 Membrane - - - 0.000000000000000000000000000000000000000000000000000003805 202.0
HFD1_k127_7114849_5 Hemerythrin hhe cation binding - - - 0.000000000000000000000000000000000000000001259 160.0
HFD1_k127_7114849_6 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000001754 116.0
HFD1_k127_7114849_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000001485 86.0
HFD1_k127_7114849_8 Belongs to the CinA family - - - 0.000000000000007149 81.0
HFD1_k127_7114849_9 PFAM Plasmid stabilisation system protein - - - 0.000000003272 62.0
HFD1_k127_717917_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 537.0
HFD1_k127_717917_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 486.0
HFD1_k127_717917_10 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000003397 175.0
HFD1_k127_717917_11 PQQ-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000001609 175.0
HFD1_k127_717917_12 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000001769 175.0
HFD1_k127_717917_13 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000001693 148.0
HFD1_k127_717917_14 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000623 142.0
HFD1_k127_717917_15 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000002254 128.0
HFD1_k127_717917_16 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000005433 123.0
HFD1_k127_717917_17 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000006919 117.0
HFD1_k127_717917_18 tetraacyldisaccharide 4'-kinase activity K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.000000000000000000000008898 100.0
HFD1_k127_717917_19 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000165 90.0
HFD1_k127_717917_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 485.0
HFD1_k127_717917_20 - - - - 0.000000000000003135 78.0
HFD1_k127_717917_21 Transposase (IS116 IS110 IS902 family) K07486 - - 0.00000000000007735 72.0
HFD1_k127_717917_22 Phage integrase family - - - 0.0000006492 53.0
HFD1_k127_717917_3 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 371.0
HFD1_k127_717917_4 Alkyl hydroperoxide reductase and or thiol-specific antioxidant family (AhpC TSA) protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 300.0
HFD1_k127_717917_5 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 315.0
HFD1_k127_717917_6 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 289.0
HFD1_k127_717917_7 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
HFD1_k127_717917_8 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001852 256.0
HFD1_k127_717917_9 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000005666 248.0
HFD1_k127_7201290_0 aminopeptidase activity K01301 - 3.4.17.21 8.671e-315 981.0
HFD1_k127_7201290_1 Peptidase family M1 domain - - - 3.706e-258 807.0
HFD1_k127_7201290_2 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000001297 191.0
HFD1_k127_7201290_3 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000001871 154.0
HFD1_k127_7201290_4 SET domain K07117 - - 0.000000000000000000000000000001057 125.0
HFD1_k127_7201290_5 Low-density lipoprotein-receptor YWTD domain - - - 0.000009671 60.0
HFD1_k127_7229530_0 Sortilin, neurotensin receptor 3, - - - 0.0 1353.0
HFD1_k127_7229530_1 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000003257 212.0
HFD1_k127_7248189_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.407e-297 933.0
HFD1_k127_7248189_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 6.812e-257 820.0
HFD1_k127_7248189_10 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000002521 218.0
HFD1_k127_7248189_11 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000335 212.0
HFD1_k127_7248189_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000001393 165.0
HFD1_k127_7248189_13 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000002994 162.0
HFD1_k127_7248189_14 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000005349 139.0
HFD1_k127_7248189_15 Transposase - - - 0.0000000000000000000000000000001764 125.0
HFD1_k127_7248189_16 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000001476 102.0
HFD1_k127_7248189_17 O-Antigen ligase K18814 - - 0.00000000000000000004134 105.0
HFD1_k127_7248189_18 Lipopolysaccharide-assembly - - - 0.0000000000000005735 87.0
HFD1_k127_7248189_19 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000003941 78.0
HFD1_k127_7248189_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 3.558e-216 679.0
HFD1_k127_7248189_20 Modulates RecA activity K03565 - - 0.000000000003297 74.0
HFD1_k127_7248189_21 - - - - 0.000000000005922 70.0
HFD1_k127_7248189_22 - - - - 0.000000000007335 77.0
HFD1_k127_7248189_23 Transposase K07491 - - 0.000000001697 61.0
HFD1_k127_7248189_3 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 2.907e-215 682.0
HFD1_k127_7248189_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 608.0
HFD1_k127_7248189_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 361.0
HFD1_k127_7248189_6 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 318.0
HFD1_k127_7248189_7 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000005265 228.0
HFD1_k127_7248189_8 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000002334 226.0
HFD1_k127_7248189_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000004679 226.0
HFD1_k127_7262447_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 575.0
HFD1_k127_7262447_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 563.0
HFD1_k127_7262447_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 466.0
HFD1_k127_7262447_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 407.0
HFD1_k127_7262447_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 264.0
HFD1_k127_7262447_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000008744 257.0
HFD1_k127_7262447_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000359 224.0
HFD1_k127_7262447_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000003515 222.0
HFD1_k127_7262447_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000008758 151.0
HFD1_k127_7262447_9 Glutamyl-tRNAGlu reductase, N-terminal domain K02492 - 1.2.1.70 0.0000000000000000000000001263 117.0
HFD1_k127_7274562_0 transport - - - 0.0 1098.0
HFD1_k127_7274562_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1042.0
HFD1_k127_7274562_10 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 340.0
HFD1_k127_7274562_11 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 330.0
HFD1_k127_7274562_12 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 295.0
HFD1_k127_7274562_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007957 272.0
HFD1_k127_7274562_14 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008081 265.0
HFD1_k127_7274562_15 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009391 257.0
HFD1_k127_7274562_16 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000000000000000000002326 244.0
HFD1_k127_7274562_17 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000805 236.0
HFD1_k127_7274562_18 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000004371 226.0
HFD1_k127_7274562_19 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000009839 197.0
HFD1_k127_7274562_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.563e-311 966.0
HFD1_k127_7274562_20 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000001263 192.0
HFD1_k127_7274562_21 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000006886 198.0
HFD1_k127_7274562_22 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000003789 183.0
HFD1_k127_7274562_23 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000005575 175.0
HFD1_k127_7274562_24 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000007883 186.0
HFD1_k127_7274562_25 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000008087 171.0
HFD1_k127_7274562_26 AI-2E family transporter - - - 0.000000000000000000000000000000000005498 152.0
HFD1_k127_7274562_27 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000001441 147.0
HFD1_k127_7274562_28 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000001192 133.0
HFD1_k127_7274562_29 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000001226 130.0
HFD1_k127_7274562_3 cell adhesion involved in biofilm formation K02014,K11031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 653.0
HFD1_k127_7274562_30 Glutathione peroxidase K02199 - - 0.00000000000000000000000003999 114.0
HFD1_k127_7274562_31 Phospholipid methyltransferase - - - 0.00000000000000000000000252 109.0
HFD1_k127_7274562_32 Domain of unknown function (DUF4112) - - - 0.00000000000000000007148 96.0
HFD1_k127_7274562_33 - - - - 0.0000000000000000004333 94.0
HFD1_k127_7274562_34 Polymer-forming cytoskeletal - - - 0.00000000000000001581 91.0
HFD1_k127_7274562_35 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000001313 81.0
HFD1_k127_7274562_36 PFAM aminotransferase, class I K10907 - - 0.0000000000000003099 79.0
HFD1_k127_7274562_37 Domain of unknown function (DUF4129) - - - 0.0000000000000007474 89.0
HFD1_k127_7274562_38 - - - - 0.00000000001722 76.0
HFD1_k127_7274562_4 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 464.0
HFD1_k127_7274562_40 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000002257 72.0
HFD1_k127_7274562_41 Putative 2OG-Fe(II) oxygenase - - - 0.00000002186 65.0
HFD1_k127_7274562_42 protein homotetramerization - - - 0.00000004266 58.0
HFD1_k127_7274562_43 Domain of unknown function (DUF4350) - - - 0.00000005233 65.0
HFD1_k127_7274562_45 von Willebrand factor, type A - - - 0.0000001331 55.0
HFD1_k127_7274562_46 gas vesicle protein - - - 0.000001017 58.0
HFD1_k127_7274562_5 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 439.0
HFD1_k127_7274562_6 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 449.0
HFD1_k127_7274562_7 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 400.0
HFD1_k127_7274562_8 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 375.0
HFD1_k127_7274562_9 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 362.0
HFD1_k127_7294964_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.598e-207 657.0
HFD1_k127_7294964_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 364.0
HFD1_k127_7294964_2 Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000002858 178.0
HFD1_k127_7294964_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000008368 181.0
HFD1_k127_7294964_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000006572 117.0
HFD1_k127_7294964_5 PFAM peptidase M22 glycoprotease K01409,K14742 - 2.3.1.234 0.000000000000000000000002305 112.0
HFD1_k127_7294964_6 PQQ enzyme repeat - - - 0.000000000000000000000006518 115.0
HFD1_k127_7294964_7 Protein of unknown function (DUF465) - - - 0.000000002355 63.0
HFD1_k127_7294964_8 Periplasmic or secreted lipoprotein - - - 0.000000002856 58.0
HFD1_k127_7315913_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 383.0
HFD1_k127_7315913_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 342.0
HFD1_k127_7315913_2 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000005388 256.0
HFD1_k127_7315913_3 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000002185 188.0
HFD1_k127_7315913_4 PhoU domain K02039 - - 0.000000000000000000000000000000000000000000000004736 180.0
HFD1_k127_7328000_0 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000000000000000000002242 191.0
HFD1_k127_7328000_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000002247 166.0
HFD1_k127_7328000_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000007551 162.0
HFD1_k127_7328000_3 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K15521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 2.4.1.250 0.0000000000000003545 87.0
HFD1_k127_7328000_4 transferase activity, transferring glycosyl groups K16703 - - 0.000000000000008112 78.0
HFD1_k127_7328000_5 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.00000000002073 72.0
HFD1_k127_7363039_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 544.0
HFD1_k127_7363039_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 535.0
HFD1_k127_7363039_10 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 320.0
HFD1_k127_7363039_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001353 292.0
HFD1_k127_7363039_12 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001692 293.0
HFD1_k127_7363039_13 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002255 258.0
HFD1_k127_7363039_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000646 252.0
HFD1_k127_7363039_15 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.0000000000000000000000000000000000000000000000000000000000000000009404 243.0
HFD1_k127_7363039_16 PQQ-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000003501 232.0
HFD1_k127_7363039_17 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000006537 215.0
HFD1_k127_7363039_18 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000009024 168.0
HFD1_k127_7363039_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000005764 151.0
HFD1_k127_7363039_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 445.0
HFD1_k127_7363039_20 PFAM Forkhead-associated protein - - - 0.000000000000000000000001909 110.0
HFD1_k127_7363039_21 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.00000000000000000000005573 109.0
HFD1_k127_7363039_22 tetratricopeptide - - - 0.0000000000000000000004512 109.0
HFD1_k127_7363039_23 Yip1 domain - - - 0.0000000001588 72.0
HFD1_k127_7363039_24 RDD family - - - 0.000000001736 66.0
HFD1_k127_7363039_25 histone H2A K63-linked ubiquitination - - - 0.00000000583 69.0
HFD1_k127_7363039_26 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000003048 60.0
HFD1_k127_7363039_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 450.0
HFD1_k127_7363039_4 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 427.0
HFD1_k127_7363039_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 399.0
HFD1_k127_7363039_6 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 395.0
HFD1_k127_7363039_7 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 367.0
HFD1_k127_7363039_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 341.0
HFD1_k127_7363039_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 347.0
HFD1_k127_7370993_0 Polysulphide reductase, NrfD - - - 9.23e-198 626.0
HFD1_k127_7370993_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 578.0
HFD1_k127_7370993_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 368.0
HFD1_k127_7370993_3 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 340.0
HFD1_k127_7370993_4 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 329.0
HFD1_k127_7370993_5 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000001235 121.0
HFD1_k127_7370993_6 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000004657 99.0
HFD1_k127_7370993_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000906 76.0
HFD1_k127_7400941_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 507.0
HFD1_k127_7400941_1 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000009548 181.0
HFD1_k127_7420048_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2654.0
HFD1_k127_7420048_1 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 6.101e-288 908.0
HFD1_k127_7420048_2 Acyl-CoA dehydrogenase, N-terminal domain K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 511.0
HFD1_k127_7420048_3 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 416.0
HFD1_k127_7420048_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 400.0
HFD1_k127_7420048_5 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 341.0
HFD1_k127_7420048_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000004923 238.0
HFD1_k127_7420048_7 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001381 211.0
HFD1_k127_7420048_8 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000005046 123.0
HFD1_k127_7420048_9 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000004301 114.0
HFD1_k127_7443215_0 Carboxyl transferase domain - - - 5.874e-231 728.0
HFD1_k127_7443215_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.42e-227 716.0
HFD1_k127_7443215_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000386 209.0
HFD1_k127_7443215_11 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000006612 198.0
HFD1_k127_7443215_12 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000002692 200.0
HFD1_k127_7443215_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000003145 167.0
HFD1_k127_7443215_14 - - - - 0.00000000000000000000000000000000000000000003675 162.0
HFD1_k127_7443215_15 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000007721 145.0
HFD1_k127_7443215_16 Ribosomal protein L35 K02916 - - 0.0000000000000000008298 87.0
HFD1_k127_7443215_17 PFAM S23 ribosomal protein - - - 0.000000000000005151 75.0
HFD1_k127_7443215_18 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000002752 54.0
HFD1_k127_7443215_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.897e-225 715.0
HFD1_k127_7443215_3 Acyclic terpene utilisation family protein AtuA - - - 4.508e-212 666.0
HFD1_k127_7443215_4 Bacterial protein of unknown function (DUF885) - - - 2.335e-204 655.0
HFD1_k127_7443215_5 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 470.0
HFD1_k127_7443215_6 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 360.0
HFD1_k127_7443215_7 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001215 276.0
HFD1_k127_7443215_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009148 264.0
HFD1_k127_7443215_9 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000003359 211.0
HFD1_k127_7463478_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 434.0
HFD1_k127_7463478_1 Putative restriction endonuclease - - - 0.000000000000000428 80.0
HFD1_k127_751025_0 response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 332.0
HFD1_k127_751025_1 C-3'',4'' desaturase CrtD - - - 0.000000000000000000000000000000000000000009113 170.0
HFD1_k127_751025_2 regulatory protein, FmdB family - - - 0.0000000000000000006893 89.0
HFD1_k127_751025_3 metal-dependent membrane protease K07052 - - 0.0000000005161 70.0
HFD1_k127_751025_4 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000002083 59.0
HFD1_k127_7516515_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.795e-230 722.0
HFD1_k127_7516515_1 Phosphotransferase enzyme family - - - 7.085e-218 700.0
HFD1_k127_7516515_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 289.0
HFD1_k127_7516515_11 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001299 270.0
HFD1_k127_7516515_12 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000943 233.0
HFD1_k127_7516515_13 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001757 220.0
HFD1_k127_7516515_14 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000001817 217.0
HFD1_k127_7516515_15 Squalene--hopene cyclase - - - 0.000000000000000000000000000000000000000000007073 168.0
HFD1_k127_7516515_16 FAD binding domain K21401 - 1.3.99.38 0.00000000000000000000000000000000000000001398 168.0
HFD1_k127_7516515_17 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000249 157.0
HFD1_k127_7516515_18 Methyltransferase domain - - - 0.0000000000000000000000000000000000000004829 158.0
HFD1_k127_7516515_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000002149 126.0
HFD1_k127_7516515_2 TonB dependent receptor - - - 6.558e-198 663.0
HFD1_k127_7516515_20 Sigma-70, region 4 - - - 0.000000000000000000000000000007881 126.0
HFD1_k127_7516515_21 VanZ like family - - - 0.000000000000000000000000327 111.0
HFD1_k127_7516515_22 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000003333 102.0
HFD1_k127_7516515_23 Protein of unknown function (DUF3224) - - - 0.000000000000000000003088 94.0
HFD1_k127_7516515_24 SMART Tetratricopeptide domain protein - - - 0.00000000000000001773 94.0
HFD1_k127_7516515_25 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000001271 74.0
HFD1_k127_7516515_26 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000687 76.0
HFD1_k127_7516515_27 belongs to the Fur family K03711,K09825 - - 0.000000000001281 69.0
HFD1_k127_7516515_28 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000005357 67.0
HFD1_k127_7516515_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 582.0
HFD1_k127_7516515_30 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein - - - 0.00000002474 62.0
HFD1_k127_7516515_31 - - - - 0.00000005233 59.0
HFD1_k127_7516515_32 Copper binding periplasmic protein CusF K07810 - - 0.0000007169 56.0
HFD1_k127_7516515_33 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00003487 47.0
HFD1_k127_7516515_34 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0006044 48.0
HFD1_k127_7516515_35 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein - - - 0.0008535 47.0
HFD1_k127_7516515_4 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 456.0
HFD1_k127_7516515_5 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 433.0
HFD1_k127_7516515_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 406.0
HFD1_k127_7516515_7 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 399.0
HFD1_k127_7516515_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 319.0
HFD1_k127_7516515_9 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 301.0
HFD1_k127_7525267_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1169.0
HFD1_k127_7525267_1 PFAM Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 583.0
HFD1_k127_7525267_10 Yqey-like protein K09117 - - 0.00000000000000000000000000000000001786 140.0
HFD1_k127_7525267_11 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000005457 132.0
HFD1_k127_7525267_12 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000001481 137.0
HFD1_k127_7525267_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 550.0
HFD1_k127_7525267_3 Protein of unknown function (DUF1211) - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009474 269.0
HFD1_k127_7525267_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005543 273.0
HFD1_k127_7525267_5 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000141 246.0
HFD1_k127_7525267_6 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000001768 199.0
HFD1_k127_7525267_7 - - - - 0.00000000000000000000000000000000000000000000000000008118 202.0
HFD1_k127_7525267_8 Phosphate acyltransferases K00655,K15781 - 2.3.1.51,3.1.3.3 0.0000000000000000000000000000000000009211 153.0
HFD1_k127_7525267_9 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000001266 149.0
HFD1_k127_7544730_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001744 311.0
HFD1_k127_7544730_1 S-layer homology domain - - - 0.000000000000000008346 100.0
HFD1_k127_7544730_2 protein import - - - 0.00000000002657 74.0
HFD1_k127_7544730_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000001435 63.0
HFD1_k127_7607361_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1098.0
HFD1_k127_7607361_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 434.0
HFD1_k127_7607361_2 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 403.0
HFD1_k127_7607361_3 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000004414 231.0
HFD1_k127_7607361_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000003026 212.0
HFD1_k127_7607361_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000271 157.0
HFD1_k127_7607361_6 ATPase AAA-2 domain protein K03696 - - 0.00000000000000000000000000001794 128.0
HFD1_k127_7680167_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 505.0
HFD1_k127_7680167_1 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 492.0
HFD1_k127_7680167_10 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000001033 123.0
HFD1_k127_7680167_12 - - - - 0.000000001278 66.0
HFD1_k127_7680167_2 PFAM alpha beta hydrolase K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 479.0
HFD1_k127_7680167_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 398.0
HFD1_k127_7680167_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 336.0
HFD1_k127_7680167_5 Major Facilitator Superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 307.0
HFD1_k127_7680167_6 Popeye protein conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000003378 239.0
HFD1_k127_7680167_7 esterase - - - 0.00000000000000000000000000000000000000000000002897 184.0
HFD1_k127_7680167_8 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.000000000000000000000000000000000000000000002271 165.0
HFD1_k127_7680167_9 Cupin domain - - - 0.000000000000000000000000000000000000000000127 162.0
HFD1_k127_779062_0 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000006608 180.0
HFD1_k127_779062_1 Epimerase dehydratase K01784,K12454 - 5.1.3.10,5.1.3.2 0.00000000000000000000000001863 120.0
HFD1_k127_7934846_0 DEAD DEAH box helicase K03724 - - 0.0 1699.0
HFD1_k127_7934846_1 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 573.0
HFD1_k127_7934846_10 EamA-like transporter family - - - 0.0000000000000000000000000000001114 128.0
HFD1_k127_7934846_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000003298 119.0
HFD1_k127_7934846_12 Domain of unknown function (DUF4160) - - - 0.0000000000000000000000000005141 114.0
HFD1_k127_7934846_13 hyperosmotic response - - - 0.000000000000000000000000002261 117.0
HFD1_k127_7934846_14 COG3668 Plasmid stabilization system protein - - - 0.0000000000000000000000001817 108.0
HFD1_k127_7934846_15 cellulase activity - - - 0.00000000000000000008749 104.0
HFD1_k127_7934846_16 - - - - 0.00000000000003607 75.0
HFD1_k127_7934846_17 - - - - 0.000000000003169 68.0
HFD1_k127_7934846_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 464.0
HFD1_k127_7934846_3 PFAM ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 459.0
HFD1_k127_7934846_4 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 455.0
HFD1_k127_7934846_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 448.0
HFD1_k127_7934846_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000525 205.0
HFD1_k127_7934846_7 Domain of unknown function (DUF4142) - - - 0.0000000000000000000000000000000000002723 146.0
HFD1_k127_7934846_8 Membrane - - - 0.000000000000000000000000000000000003699 143.0
HFD1_k127_7934846_9 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000008635 126.0
HFD1_k127_796739_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 430.0
HFD1_k127_796739_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 397.0
HFD1_k127_796739_10 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions - - - 0.0007178 45.0
HFD1_k127_796739_2 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 350.0
HFD1_k127_796739_3 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000118 237.0
HFD1_k127_796739_5 PFAM glycosyl transferase family 39 K14340 - - 0.000000000000000000000000000000000000000000000000003859 203.0
HFD1_k127_796739_6 hydrolase of the alpha beta K07018 - - 0.000000000000000000000000000000000000000000000007291 179.0
HFD1_k127_796739_7 Methyltransferase domain - - - 0.000000000000000000000006299 118.0
HFD1_k127_796739_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000001622 81.0
HFD1_k127_796739_9 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564 3.1.3.48 0.00000008862 60.0
HFD1_k127_807426_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1994.0
HFD1_k127_807426_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1924.0
HFD1_k127_807426_10 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000001347 181.0
HFD1_k127_807426_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000004336 157.0
HFD1_k127_807426_12 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000001266 159.0
HFD1_k127_807426_13 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000001103 156.0
HFD1_k127_807426_14 - - - - 0.000000000000000000000000000002873 131.0
HFD1_k127_807426_15 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000002288 124.0
HFD1_k127_807426_16 - - - - 0.00000000000000000000000001004 111.0
HFD1_k127_807426_17 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000005451 100.0
HFD1_k127_807426_18 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000004157 87.0
HFD1_k127_807426_19 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000008281 70.0
HFD1_k127_807426_2 cellulose binding - - - 0.0 1069.0
HFD1_k127_807426_20 Peptidase P60 K21471 - - 0.00000000002864 72.0
HFD1_k127_807426_21 Cysteine-rich CWC - - - 0.0000006545 55.0
HFD1_k127_807426_22 - - - - 0.00003851 51.0
HFD1_k127_807426_23 - - - - 0.0002231 46.0
HFD1_k127_807426_24 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0008796 48.0
HFD1_k127_807426_3 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 508.0
HFD1_k127_807426_4 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 377.0
HFD1_k127_807426_5 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 305.0
HFD1_k127_807426_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000005975 213.0
HFD1_k127_807426_7 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000001011 214.0
HFD1_k127_807426_8 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000001628 220.0
HFD1_k127_807426_9 peptidyl-tyrosine sulfation K03217,K06872 - - 0.0000000000000000000000000000000000000000000000000000005769 207.0
HFD1_k127_829689_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 452.0
HFD1_k127_829689_1 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 325.0
HFD1_k127_869813_0 Amino acid permease - - - 3.326e-209 668.0
HFD1_k127_869813_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 407.0
HFD1_k127_869813_2 PFAM Peptidase M1 membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 338.0
HFD1_k127_869813_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000001711 203.0
HFD1_k127_869813_4 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000004317 158.0
HFD1_k127_869813_5 Probable zinc-ribbon domain - - - 0.0000000000000000000000000002232 118.0
HFD1_k127_869813_6 - - - - 0.00000000000000000006989 99.0
HFD1_k127_869813_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000001709 69.0
HFD1_k127_869813_8 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.00000000002419 71.0
HFD1_k127_917018_0 PFAM peptidase M13 K01415 - 3.4.24.71 2.007e-216 692.0
HFD1_k127_917018_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 348.0
HFD1_k127_917018_2 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
HFD1_k127_917018_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000007709 218.0
HFD1_k127_917018_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000105 168.0
HFD1_k127_919962_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 8.62e-282 880.0
HFD1_k127_919962_1 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 471.0
HFD1_k127_919962_2 Protein of unknown function (DUF434) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001082 284.0
HFD1_k127_919962_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000004957 168.0
HFD1_k127_919962_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000004317 111.0
HFD1_k127_919962_5 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.00006322 51.0
HFD1_k127_936000_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.456e-271 848.0
HFD1_k127_936000_1 Belongs to the peptidase M16 family K07263 - - 1.861e-257 826.0
HFD1_k127_936000_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 389.0
HFD1_k127_936000_11 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 380.0
HFD1_k127_936000_12 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 344.0
HFD1_k127_936000_13 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 327.0
HFD1_k127_936000_14 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 332.0
HFD1_k127_936000_15 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 324.0
HFD1_k127_936000_16 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 307.0
HFD1_k127_936000_17 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 315.0
HFD1_k127_936000_18 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 306.0
HFD1_k127_936000_19 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 298.0
HFD1_k127_936000_2 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 1.411e-200 637.0
HFD1_k127_936000_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000002924 227.0
HFD1_k127_936000_21 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000003482 211.0
HFD1_k127_936000_22 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000008251 193.0
HFD1_k127_936000_23 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000002729 180.0
HFD1_k127_936000_24 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000568 184.0
HFD1_k127_936000_25 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000002829 168.0
HFD1_k127_936000_26 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000001641 165.0
HFD1_k127_936000_27 BMC domain - - - 0.000000000000000000000000000000001391 131.0
HFD1_k127_936000_28 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00000000000000000000000000001422 123.0
HFD1_k127_936000_29 Tyrosine phosphatase family - - - 0.00000000000000000000000001483 116.0
HFD1_k127_936000_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 524.0
HFD1_k127_936000_30 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000007121 98.0
HFD1_k127_936000_31 Hfq protein - - - 0.0000000000000000000008007 102.0
HFD1_k127_936000_32 Belongs to the UPF0761 family K07058 - - 0.000000000000000003958 96.0
HFD1_k127_936000_33 response regulator, receiver - - - 0.0000000000000000785 85.0
HFD1_k127_936000_34 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000001902 83.0
HFD1_k127_936000_35 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000001752 76.0
HFD1_k127_936000_36 Tetratricopeptide repeat - - - 0.0000000007527 69.0
HFD1_k127_936000_37 Cell division protein FtsQ K03589 - - 0.000000006373 68.0
HFD1_k127_936000_38 Prokaryotic N-terminal methylation motif K02456 - - 0.0004101 50.0
HFD1_k127_936000_4 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 503.0
HFD1_k127_936000_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528,K16203 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 447.0
HFD1_k127_936000_6 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 438.0
HFD1_k127_936000_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 419.0
HFD1_k127_936000_8 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 399.0
HFD1_k127_936000_9 Phytanoyl-CoA dioxygenase (PhyH) K00477 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 385.0
HFD1_k127_960029_0 Sodium:sulfate symporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 561.0
HFD1_k127_960029_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 509.0
HFD1_k127_960029_10 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 397.0
HFD1_k127_960029_11 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 383.0
HFD1_k127_960029_12 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 368.0
HFD1_k127_960029_13 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 368.0
HFD1_k127_960029_14 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 367.0
HFD1_k127_960029_15 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 346.0
HFD1_k127_960029_16 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 346.0
HFD1_k127_960029_17 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 331.0
HFD1_k127_960029_18 ATPases associated with a variety of cellular activities K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 315.0
HFD1_k127_960029_19 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001414 293.0
HFD1_k127_960029_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 509.0
HFD1_k127_960029_20 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000003736 221.0
HFD1_k127_960029_21 PAS domain containing protein K21084 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000005162 225.0
HFD1_k127_960029_22 methyltransferase - - - 0.000000000000000000000000000000000000000000001486 171.0
HFD1_k127_960029_23 phosphoprotein phosphatase activity K07313 - 3.1.3.16 0.000000000000000000000000000000000007155 147.0
HFD1_k127_960029_24 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000001467 142.0
HFD1_k127_960029_25 - - - - 0.00000000000000000000000000000000002704 140.0
HFD1_k127_960029_26 - - - - 0.00000000000000000000000001421 123.0
HFD1_k127_960029_27 Domain of unknown function (DUF4160) - - - 0.00000000000000000000001366 102.0
HFD1_k127_960029_28 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000003542 91.0
HFD1_k127_960029_29 cheY-homologous receiver domain K03413 - - 0.000000000000000005203 89.0
HFD1_k127_960029_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 494.0
HFD1_k127_960029_31 Protein of unknown function (DUF2442) - - - 0.00000000000000002155 84.0
HFD1_k127_960029_32 DoxX K15977 - - 0.00000000000000006846 87.0
HFD1_k127_960029_33 peptidylprolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.00000000002198 77.0
HFD1_k127_960029_35 Tetratricopeptide repeat - - - 0.0003753 52.0
HFD1_k127_960029_4 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 462.0
HFD1_k127_960029_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 439.0
HFD1_k127_960029_6 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 418.0
HFD1_k127_960029_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 434.0
HFD1_k127_960029_8 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 398.0
HFD1_k127_960029_9 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 387.0
HFD1_k127_971223_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 9.294e-246 773.0
HFD1_k127_971223_1 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 612.0
HFD1_k127_971223_10 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 448.0
HFD1_k127_971223_11 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 391.0
HFD1_k127_971223_12 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 394.0
HFD1_k127_971223_13 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 367.0
HFD1_k127_971223_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 366.0
HFD1_k127_971223_15 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 403.0
HFD1_k127_971223_16 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 358.0
HFD1_k127_971223_17 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 341.0
HFD1_k127_971223_18 epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 336.0
HFD1_k127_971223_19 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002995 288.0
HFD1_k127_971223_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 591.0
HFD1_k127_971223_20 Amino acid transporter K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001434 291.0
HFD1_k127_971223_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001151 246.0
HFD1_k127_971223_22 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000001971 228.0
HFD1_k127_971223_23 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001083 196.0
HFD1_k127_971223_24 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000001011 207.0
HFD1_k127_971223_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000003122 169.0
HFD1_k127_971223_26 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000004473 161.0
HFD1_k127_971223_27 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000191 166.0
HFD1_k127_971223_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000001674 140.0
HFD1_k127_971223_29 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000002595 133.0
HFD1_k127_971223_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 512.0
HFD1_k127_971223_30 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000001094 123.0
HFD1_k127_971223_31 Extracellular nuclease K07004 - - 0.00000000000000000000000000004253 138.0
HFD1_k127_971223_32 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000689 121.0
HFD1_k127_971223_33 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000002303 109.0
HFD1_k127_971223_34 Lamin Tail Domain - - - 0.000000000000000000000001887 123.0
HFD1_k127_971223_35 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000009624 105.0
HFD1_k127_971223_36 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000005996 115.0
HFD1_k127_971223_37 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000001244 93.0
HFD1_k127_971223_38 Dodecin K09165 - - 0.0000000000000000001176 89.0
HFD1_k127_971223_39 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000004599 98.0
HFD1_k127_971223_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 507.0
HFD1_k127_971223_40 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000000002448 80.0
HFD1_k127_971223_41 Thioredoxin-like - - - 0.000000000000003843 83.0
HFD1_k127_971223_43 BON domain - - - 0.00000000000001882 79.0
HFD1_k127_971223_44 - - - - 0.00000000000008347 80.0
HFD1_k127_971223_45 Protein of unknown function (DUF3309) - - - 0.0000000000001002 76.0
HFD1_k127_971223_46 Carboxypeptidase regulatory-like domain - - - 0.0000000000003152 83.0
HFD1_k127_971223_47 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.000000000001176 78.0
HFD1_k127_971223_48 Lysin motif - - - 0.00000000008998 67.0
HFD1_k127_971223_49 - - - - 0.0000000007493 62.0
HFD1_k127_971223_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 512.0
HFD1_k127_971223_50 Tetratricopeptide repeat - - - 0.000003599 55.0
HFD1_k127_971223_52 Large extracellular alpha-helical protein K12548,K13735 - - 0.00006507 58.0
HFD1_k127_971223_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 488.0
HFD1_k127_971223_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 488.0
HFD1_k127_971223_8 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 456.0
HFD1_k127_971223_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 442.0