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Overview

ID MAG01619
Name HFD1_bin.29
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus Sulfobium
Species
Assembly information
Completeness (%) 99.93
Contamination (%) 1.07
GC content (%) 49.0
N50 (bp) 25,010
Genome size (bp) 3,077,682

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2911

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1001455_0 surface antigen variable number repeat protein K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 548.0
HFD1_k127_1001455_1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 428.0
HFD1_k127_1001455_10 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000004154 141.0
HFD1_k127_1001455_12 - - - - 0.000000000000000000000000000004063 126.0
HFD1_k127_1001455_13 PFAM Rhodanese domain protein - - - 0.000000000000000000000000002512 118.0
HFD1_k127_1001455_14 FtsX-like permease family K02004 - - 0.00000000000000000000001626 101.0
HFD1_k127_1001455_15 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.0000000000000000000001418 102.0
HFD1_k127_1001455_16 FtsX-like permease family K02004 - - 0.000000001557 60.0
HFD1_k127_1001455_17 Belongs to the pirin family K06911 - - 0.000004765 50.0
HFD1_k127_1001455_18 Pyruvate formate-lyase K20038 - 4.3.99.4 0.0001283 47.0
HFD1_k127_1001455_2 Protein of unknown function K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 449.0
HFD1_k127_1001455_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 368.0
HFD1_k127_1001455_4 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 282.0
HFD1_k127_1001455_5 GHKL domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000006367 262.0
HFD1_k127_1001455_6 - - - - 0.0000000000000000000000000000000000000000000000001074 181.0
HFD1_k127_1001455_7 Cysteine rich repeat - - - 0.000000000000000000000000000000000000000000001916 168.0
HFD1_k127_1001455_8 Cysteine rich repeat - - - 0.0000000000000000000000000000000000000000006526 163.0
HFD1_k127_1001455_9 YMGG-like Gly-zipper - - - 0.000000000000000000000000000000000000000002137 161.0
HFD1_k127_1012864_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000006798 176.0
HFD1_k127_1012864_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000001021 169.0
HFD1_k127_1012864_2 Domain of unknown function (DUF4253) - - - 0.000000000000000000000000000000000000007915 154.0
HFD1_k127_1012864_3 Histidine kinase - - - 0.00000000000000000000000000002995 122.0
HFD1_k127_1012864_4 Cysteine-rich small domain K07162 - - 0.0000000000000000000007301 96.0
HFD1_k127_1012864_5 Rhodanese Homology Domain - - - 0.000000000000000004696 85.0
HFD1_k127_1012864_6 YtkA-like - - - 0.00000000007568 68.0
HFD1_k127_1012864_7 signal transduction protein with EFhand domain - - - 0.00000257 50.0
HFD1_k127_103316_0 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000003349 195.0
HFD1_k127_103316_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000007013 166.0
HFD1_k127_103316_2 acetyltransferase - - - 0.0000000000000001539 89.0
HFD1_k127_1068902_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 358.0
HFD1_k127_1068902_1 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000001902 228.0
HFD1_k127_1068902_2 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000008204 154.0
HFD1_k127_1068902_3 - - - - 0.0000001002 54.0
HFD1_k127_1085703_0 response regulator receiver K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 402.0
HFD1_k127_1085703_1 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 353.0
HFD1_k127_1085703_2 radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000003925 213.0
HFD1_k127_1085703_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000584 186.0
HFD1_k127_1085703_4 Autoinducer binding domain - - - 0.000000000000006655 76.0
HFD1_k127_108771_0 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 492.0
HFD1_k127_108771_1 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000001358 177.0
HFD1_k127_108771_2 - - - - 0.00000000000000000000000001004 111.0
HFD1_k127_108771_3 phosphorelay signal transduction system - - - 0.0000000000000000000000001845 111.0
HFD1_k127_108771_4 - - - - 0.0000000000000002401 80.0
HFD1_k127_108771_5 - - - - 0.0000000000000002944 79.0
HFD1_k127_108771_6 Protein of unknown function (DUF3096) - - - 0.0000000001244 62.0
HFD1_k127_108771_7 - - - - 0.000000006787 58.0
HFD1_k127_108771_8 - - - - 0.00000003289 55.0
HFD1_k127_1121749_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 374.0
HFD1_k127_1121749_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 362.0
HFD1_k127_1121749_10 Phage integrase SAM-like domain - - - 0.000000000000000000001804 107.0
HFD1_k127_1121749_12 Cytochrome C oxidase, cbb3-type, subunit III K02305 - - 0.000000000000000001737 89.0
HFD1_k127_1121749_13 - - - - 0.0000000000005584 70.0
HFD1_k127_1121749_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000004101 66.0
HFD1_k127_1121749_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 340.0
HFD1_k127_1121749_3 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 299.0
HFD1_k127_1121749_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001213 290.0
HFD1_k127_1121749_5 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000284 262.0
HFD1_k127_1121749_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000001104 267.0
HFD1_k127_1121749_7 PFAM 4Fe-4S binding domain - - - 0.0000000000000000000000000000000006004 132.0
HFD1_k127_1121749_8 - - - - 0.000000000000000000000006759 104.0
HFD1_k127_1121749_9 toxin-antitoxin pair type II binding - - - 0.0000000000000000000002196 99.0
HFD1_k127_1144992_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.55e-252 782.0
HFD1_k127_1144992_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.349e-243 759.0
HFD1_k127_1144992_10 S-methyl-5'-thioadenosine phosphorylase K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004645,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010033,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017061,GO:0017144,GO:0019221,GO:0019509,GO:0019752,GO:0023052,GO:0032259,GO:0034097,GO:0034641,GO:0035722,GO:0042221,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070671,GO:0070887,GO:0071265,GO:0071267,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 321.0
HFD1_k127_1144992_11 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
HFD1_k127_1144992_12 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 321.0
HFD1_k127_1144992_13 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 293.0
HFD1_k127_1144992_14 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 300.0
HFD1_k127_1144992_15 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 298.0
HFD1_k127_1144992_16 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000001477 263.0
HFD1_k127_1144992_17 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000004681 221.0
HFD1_k127_1144992_18 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000006418 195.0
HFD1_k127_1144992_19 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000002517 197.0
HFD1_k127_1144992_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 5.058e-238 759.0
HFD1_k127_1144992_20 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000008826 173.0
HFD1_k127_1144992_21 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000008925 158.0
HFD1_k127_1144992_22 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000002834 155.0
HFD1_k127_1144992_23 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000002025 136.0
HFD1_k127_1144992_24 PFAM transposase mutator type - - - 0.00000000000000000000000000000001056 132.0
HFD1_k127_1144992_25 radical SAM domain protein - - - 0.00000000000000000000000000000001342 138.0
HFD1_k127_1144992_26 nickel cation binding K04651,K19640 - - 0.000000000000000000000000000000017 130.0
HFD1_k127_1144992_27 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000008528 120.0
HFD1_k127_1144992_28 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000000000000000002647 117.0
HFD1_k127_1144992_29 YtxH-like protein - - - 0.00000000000000000000000003908 110.0
HFD1_k127_1144992_3 GAF domain - - - 6.556e-200 674.0
HFD1_k127_1144992_31 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.0000000000000261 74.0
HFD1_k127_1144992_32 PFAM Disulphide bond isomerase, DsbC G-like K03981 - 5.3.4.1 0.00000000000006218 80.0
HFD1_k127_1144992_33 Tetratricopeptide repeat - - - 0.000000000004482 76.0
HFD1_k127_1144992_34 Evidence 4 Homologs of previously reported genes of - - - 0.0000000007877 64.0
HFD1_k127_1144992_36 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000009381 53.0
HFD1_k127_1144992_37 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0002065 44.0
HFD1_k127_1144992_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 538.0
HFD1_k127_1144992_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 432.0
HFD1_k127_1144992_6 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 441.0
HFD1_k127_1144992_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 426.0
HFD1_k127_1144992_8 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 361.0
HFD1_k127_1144992_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 335.0
HFD1_k127_1197837_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 554.0
HFD1_k127_1197837_1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 510.0
HFD1_k127_1197837_10 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000005975 213.0
HFD1_k127_1197837_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000001655 205.0
HFD1_k127_1197837_12 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000002881 203.0
HFD1_k127_1197837_13 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000001911 167.0
HFD1_k127_1197837_14 YGGT family K02221 - - 0.000000000000000000000000000003522 123.0
HFD1_k127_1197837_15 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000003145 91.0
HFD1_k127_1197837_16 metal-dependent phosphohydrolase HD region - - - 0.000000000006925 66.0
HFD1_k127_1197837_17 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000001654 68.0
HFD1_k127_1197837_18 Diguanylate cyclase - - - 0.0003215 45.0
HFD1_k127_1197837_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 466.0
HFD1_k127_1197837_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 449.0
HFD1_k127_1197837_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 455.0
HFD1_k127_1197837_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 405.0
HFD1_k127_1197837_6 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002445 266.0
HFD1_k127_1197837_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006695 243.0
HFD1_k127_1197837_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000008717 244.0
HFD1_k127_1197837_9 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000005476 224.0
HFD1_k127_1209008_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 5.841e-211 663.0
HFD1_k127_1209008_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 585.0
HFD1_k127_1209008_10 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 404.0
HFD1_k127_1209008_11 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 374.0
HFD1_k127_1209008_12 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 369.0
HFD1_k127_1209008_13 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
HFD1_k127_1209008_14 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 338.0
HFD1_k127_1209008_15 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 307.0
HFD1_k127_1209008_16 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 293.0
HFD1_k127_1209008_17 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 286.0
HFD1_k127_1209008_18 2 iron, 2 sulfur cluster binding K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 273.0
HFD1_k127_1209008_19 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002242 269.0
HFD1_k127_1209008_2 Phosphoglucan, water dikinase K15535 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019200,GO:0019538,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044275,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046777,GO:0046835,GO:0051752,GO:0071704,GO:1901564,GO:1901575 2.7.9.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 590.0
HFD1_k127_1209008_20 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003379 239.0
HFD1_k127_1209008_21 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004881 239.0
HFD1_k127_1209008_22 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000003138 213.0
HFD1_k127_1209008_23 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000001411 191.0
HFD1_k127_1209008_24 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000000000000000000004943 156.0
HFD1_k127_1209008_25 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001194 154.0
HFD1_k127_1209008_26 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000002136 158.0
HFD1_k127_1209008_27 - - - - 0.00000000000000000000000000000000000000002165 160.0
HFD1_k127_1209008_28 - - - - 0.0000000000000000000000000000000000000007227 152.0
HFD1_k127_1209008_29 NMT1-like family K02051,K15551 - - 0.000000000000000000000000000000000000001174 160.0
HFD1_k127_1209008_3 Major facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 531.0
HFD1_k127_1209008_30 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000001748 160.0
HFD1_k127_1209008_31 Thiamine-binding protein - - - 0.0000000000000000000000000000000005034 133.0
HFD1_k127_1209008_32 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000005656 126.0
HFD1_k127_1209008_33 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000001262 111.0
HFD1_k127_1209008_34 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000268 113.0
HFD1_k127_1209008_35 - - - - 0.000000000000000000001383 95.0
HFD1_k127_1209008_36 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000001501 93.0
HFD1_k127_1209008_37 AhpC/TSA family K03386 - 1.11.1.15 0.000000000000003123 76.0
HFD1_k127_1209008_38 Xylose isomerase-like TIM barrel - - - 0.0000005544 64.0
HFD1_k127_1209008_39 peptidyl-tyrosine sulfation - - - 0.000008062 55.0
HFD1_k127_1209008_4 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 543.0
HFD1_k127_1209008_40 starch, H2O dikinase activity K08244 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009608,GO:0009610,GO:0009620,GO:0009628,GO:0009631,GO:0009941,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0031967,GO:0031975,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050521,GO:0050896,GO:0051704,GO:0051707,GO:0071704,GO:1901575 2.7.9.4 0.0001172 44.0
HFD1_k127_1209008_41 - - - - 0.0006046 45.0
HFD1_k127_1209008_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 477.0
HFD1_k127_1209008_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 466.0
HFD1_k127_1209008_7 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 464.0
HFD1_k127_1209008_8 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 420.0
HFD1_k127_1209008_9 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 412.0
HFD1_k127_1240419_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.364e-270 839.0
HFD1_k127_1240419_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 9.052e-265 827.0
HFD1_k127_1240419_10 response regulator K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 497.0
HFD1_k127_1240419_11 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 475.0
HFD1_k127_1240419_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 449.0
HFD1_k127_1240419_13 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 430.0
HFD1_k127_1240419_14 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 426.0
HFD1_k127_1240419_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 421.0
HFD1_k127_1240419_16 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 376.0
HFD1_k127_1240419_17 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 364.0
HFD1_k127_1240419_18 histidine kinase, HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 357.0
HFD1_k127_1240419_19 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 335.0
HFD1_k127_1240419_2 NADH-quinone oxidoreductase K00341 - 1.6.5.3 7.237e-248 780.0
HFD1_k127_1240419_20 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 330.0
HFD1_k127_1240419_21 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 299.0
HFD1_k127_1240419_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001815 284.0
HFD1_k127_1240419_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002442 255.0
HFD1_k127_1240419_24 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000007321 237.0
HFD1_k127_1240419_25 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000001065 232.0
HFD1_k127_1240419_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001054 205.0
HFD1_k127_1240419_27 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000002523 181.0
HFD1_k127_1240419_28 cobalamin synthesis protein, P47K - - - 0.00000000000000000000000000000000000000000000001269 181.0
HFD1_k127_1240419_29 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000000000000002814 175.0
HFD1_k127_1240419_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 8.837e-196 622.0
HFD1_k127_1240419_30 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000004966 172.0
HFD1_k127_1240419_31 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.00000000000000000000000000000000000000000000005699 181.0
HFD1_k127_1240419_32 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000005643 166.0
HFD1_k127_1240419_33 anti-sigma regulatory factor - - - 0.000000000000000000000000000000000000000001726 160.0
HFD1_k127_1240419_34 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000006547 153.0
HFD1_k127_1240419_35 Ferredoxin K17992 - 1.12.1.3 0.00000000000000000000000000000000000001638 148.0
HFD1_k127_1240419_36 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 - - 0.00000000000000000000000000000000000003479 156.0
HFD1_k127_1240419_37 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000002507 146.0
HFD1_k127_1240419_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000003522 144.0
HFD1_k127_1240419_39 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000005084 135.0
HFD1_k127_1240419_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 578.0
HFD1_k127_1240419_40 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000558 131.0
HFD1_k127_1240419_41 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000002678 122.0
HFD1_k127_1240419_42 response to copper ion K07156,K14166 - - 0.000000000000000000000000000004986 123.0
HFD1_k127_1240419_43 DRTGG domain - - - 0.00000000000000000000000000007933 119.0
HFD1_k127_1240419_44 DRTGG domain - - - 0.0000000000000000000000000211 112.0
HFD1_k127_1240419_45 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000002146 118.0
HFD1_k127_1240419_46 Belongs to the universal stress protein A family - - - 0.0000000000005465 79.0
HFD1_k127_1240419_47 ABC transporter substrate binding protein K01989 - - 0.00000004626 58.0
HFD1_k127_1240419_48 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000007755 59.0
HFD1_k127_1240419_49 - - - - 0.0000003184 62.0
HFD1_k127_1240419_5 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 556.0
HFD1_k127_1240419_50 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00001126 49.0
HFD1_k127_1240419_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 565.0
HFD1_k127_1240419_7 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 552.0
HFD1_k127_1240419_8 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 534.0
HFD1_k127_1240419_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 522.0
HFD1_k127_1315324_0 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000004108 104.0
HFD1_k127_1315324_1 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000001109 98.0
HFD1_k127_1315324_3 transcriptional regulator - - - 0.00000000003128 64.0
HFD1_k127_1315324_4 PFAM PKD domain - - - 0.0000000003969 71.0
HFD1_k127_1315324_5 COG2801 Transposase and inactivated derivatives - - - 0.000009161 49.0
HFD1_k127_1315324_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0001415 48.0
HFD1_k127_1317709_0 UDP binding domain K02474,K13015 - 1.1.1.136 2.726e-268 834.0
HFD1_k127_1317709_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 494.0
HFD1_k127_1317709_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 344.0
HFD1_k127_1317709_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000003453 64.0
HFD1_k127_1466701_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 3.827e-269 854.0
HFD1_k127_1466701_1 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 298.0
HFD1_k127_1466701_2 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004704 285.0
HFD1_k127_1466701_3 PFAM ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000003958 172.0
HFD1_k127_1466701_4 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000000000000004297 91.0
HFD1_k127_1466701_5 cheY-homologous receiver domain K02490 - - 0.000000000000002593 79.0
HFD1_k127_1527319_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1164.0
HFD1_k127_1527319_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 580.0
HFD1_k127_1527319_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 427.0
HFD1_k127_1527319_3 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 391.0
HFD1_k127_1527319_4 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000003048 217.0
HFD1_k127_1527319_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000292 117.0
HFD1_k127_1527319_6 - - - - 0.00000000000000000000009138 106.0
HFD1_k127_1527319_7 COG3209 Rhs family protein - - - 0.00000000000000000003994 102.0
HFD1_k127_1527319_9 Pfam:N_methyl_2 K02671 - - 0.0000002235 59.0
HFD1_k127_163206_0 kinase activity K01006,K01007 - 2.7.9.1,2.7.9.2 4.847e-283 893.0
HFD1_k127_163206_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 8.126e-282 892.0
HFD1_k127_163206_10 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 602.0
HFD1_k127_163206_11 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 589.0
HFD1_k127_163206_12 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 574.0
HFD1_k127_163206_13 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 522.0
HFD1_k127_163206_14 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 499.0
HFD1_k127_163206_15 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 485.0
HFD1_k127_163206_16 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 463.0
HFD1_k127_163206_17 isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 460.0
HFD1_k127_163206_18 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 454.0
HFD1_k127_163206_19 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 421.0
HFD1_k127_163206_2 kinase activity K01006,K01007 - 2.7.9.1,2.7.9.2 2.472e-277 878.0
HFD1_k127_163206_20 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 407.0
HFD1_k127_163206_21 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 409.0
HFD1_k127_163206_22 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 390.0
HFD1_k127_163206_23 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 399.0
HFD1_k127_163206_24 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 353.0
HFD1_k127_163206_25 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 336.0
HFD1_k127_163206_26 ribonuclease BN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 292.0
HFD1_k127_163206_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006867 273.0
HFD1_k127_163206_28 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008271 266.0
HFD1_k127_163206_29 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000001959 248.0
HFD1_k127_163206_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.294e-274 859.0
HFD1_k127_163206_30 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000735 235.0
HFD1_k127_163206_31 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000002719 239.0
HFD1_k127_163206_32 DNA-binding transcription factor activity K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000004753 227.0
HFD1_k127_163206_33 PFAM phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004884 232.0
HFD1_k127_163206_34 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000002315 234.0
HFD1_k127_163206_35 PFAM UspA - - - 0.000000000000000000000000000000000000000000000000000000000002791 218.0
HFD1_k127_163206_36 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000001579 208.0
HFD1_k127_163206_37 Universal stress protein family K07090 - - 0.000000000000000000000000000000000000000000000000000000002697 210.0
HFD1_k127_163206_38 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000001721 201.0
HFD1_k127_163206_39 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000009565 199.0
HFD1_k127_163206_4 His Kinase A (phosphoacceptor) domain - - - 3.797e-253 800.0
HFD1_k127_163206_40 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000005557 195.0
HFD1_k127_163206_41 Translation initiation factor IF-3, N-terminal domain K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000006949 186.0
HFD1_k127_163206_42 - - - - 0.00000000000000000000000000000000000000000000000002782 183.0
HFD1_k127_163206_43 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000003527 189.0
HFD1_k127_163206_44 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000344 181.0
HFD1_k127_163206_45 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000001374 184.0
HFD1_k127_163206_46 Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000002472 179.0
HFD1_k127_163206_47 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000003704 171.0
HFD1_k127_163206_48 Response regulator, receiver K11443 - - 0.000000000000000000000000000000000000000000001992 168.0
HFD1_k127_163206_49 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000001952 164.0
HFD1_k127_163206_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.828e-224 700.0
HFD1_k127_163206_50 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000004765 166.0
HFD1_k127_163206_51 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000001914 157.0
HFD1_k127_163206_52 Aminotransferase K04720 - 4.1.1.81 0.000000000000000000000000000000000000009132 158.0
HFD1_k127_163206_53 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000001202 141.0
HFD1_k127_163206_54 NADH dehydrogenase K03885 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0036094,GO:0042592,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044464,GO:0045333,GO:0048037,GO:0048878,GO:0050136,GO:0050660,GO:0050662,GO:0050801,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:0098771,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.99.3 0.00000000000000000000000000000000009881 148.0
HFD1_k127_163206_55 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000001565 136.0
HFD1_k127_163206_56 UTRA K03710 - - 0.000000000000000000000000000000007929 137.0
HFD1_k127_163206_57 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000001301 126.0
HFD1_k127_163206_58 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000001413 125.0
HFD1_k127_163206_59 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000005506 123.0
HFD1_k127_163206_6 Sigma-54 interaction domain - - - 3.141e-209 659.0
HFD1_k127_163206_60 Cold shock K03704 - - 0.000000000000000000000000001421 112.0
HFD1_k127_163206_61 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000007703 111.0
HFD1_k127_163206_62 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000008733 111.0
HFD1_k127_163206_63 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000001431 112.0
HFD1_k127_163206_65 Universal stress protein family K07090 - - 0.000000000000000000000001781 109.0
HFD1_k127_163206_66 Cold shock protein domain K03704 - - 0.00000000000000000000000231 103.0
HFD1_k127_163206_67 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000000004192 102.0
HFD1_k127_163206_68 Papain cysteine protease family protein - - - 0.000000000000000001644 86.0
HFD1_k127_163206_69 - - - - 0.00000000000000006098 83.0
HFD1_k127_163206_7 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.738e-208 659.0
HFD1_k127_163206_71 Papain family cysteine protease - - - 0.000000000002409 68.0
HFD1_k127_163206_72 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000003381 73.0
HFD1_k127_163206_73 Belongs to the universal stress protein A family - - - 0.00000000001924 70.0
HFD1_k127_163206_74 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000001283 66.0
HFD1_k127_163206_75 Evidence 4 Homologs of previously reported genes of - - - 0.0000000006226 62.0
HFD1_k127_163206_76 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000001007 65.0
HFD1_k127_163206_77 Protein of unknown function (DUF1059) - - - 0.0000002055 54.0
HFD1_k127_163206_78 AbrB family - - - 0.0000002703 55.0
HFD1_k127_163206_79 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000002041 51.0
HFD1_k127_163206_8 membrane transporter protein K07090 - - 9.444e-204 641.0
HFD1_k127_163206_81 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.000007525 49.0
HFD1_k127_163206_82 Papain cysteine protease family protein - - - 0.000009793 48.0
HFD1_k127_163206_83 Universal stress protein - - - 0.000148 51.0
HFD1_k127_163206_85 phosphorelay signal transduction system K02667 - - 0.0002478 46.0
HFD1_k127_163206_86 histidine kinase A domain protein K02482 - 2.7.13.3 0.00025 45.0
HFD1_k127_163206_87 hydrolase K01048 - 3.1.1.5 0.0003245 43.0
HFD1_k127_163206_9 PFAM Uncharacterised protein family UPF0182 K09118 - - 1.029e-199 655.0
HFD1_k127_1636791_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1206.0
HFD1_k127_1636791_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1137.0
HFD1_k127_1636791_10 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 9.574e-221 703.0
HFD1_k127_1636791_100 Copper binding periplasmic protein CusF - - - 0.00027 48.0
HFD1_k127_1636791_101 Tetratricopeptide repeat protein - - - 0.0005343 46.0
HFD1_k127_1636791_102 Methyltransferase K00563 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 0.000945 43.0
HFD1_k127_1636791_11 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 606.0
HFD1_k127_1636791_12 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 602.0
HFD1_k127_1636791_13 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 580.0
HFD1_k127_1636791_14 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 576.0
HFD1_k127_1636791_15 family UPF0324 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 567.0
HFD1_k127_1636791_16 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 566.0
HFD1_k127_1636791_17 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 512.0
HFD1_k127_1636791_18 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 502.0
HFD1_k127_1636791_19 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 498.0
HFD1_k127_1636791_2 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1099.0
HFD1_k127_1636791_20 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 488.0
HFD1_k127_1636791_21 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 460.0
HFD1_k127_1636791_22 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 445.0
HFD1_k127_1636791_23 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 406.0
HFD1_k127_1636791_24 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 410.0
HFD1_k127_1636791_25 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 392.0
HFD1_k127_1636791_26 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 381.0
HFD1_k127_1636791_27 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 372.0
HFD1_k127_1636791_28 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 368.0
HFD1_k127_1636791_29 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 342.0
HFD1_k127_1636791_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1077.0
HFD1_k127_1636791_30 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 344.0
HFD1_k127_1636791_31 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 351.0
HFD1_k127_1636791_32 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 346.0
HFD1_k127_1636791_33 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 332.0
HFD1_k127_1636791_34 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 329.0
HFD1_k127_1636791_35 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 330.0
HFD1_k127_1636791_36 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 315.0
HFD1_k127_1636791_37 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 319.0
HFD1_k127_1636791_38 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 301.0
HFD1_k127_1636791_39 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 296.0
HFD1_k127_1636791_4 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 8e-323 999.0
HFD1_k127_1636791_40 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 295.0
HFD1_k127_1636791_41 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000267 287.0
HFD1_k127_1636791_42 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000639 282.0
HFD1_k127_1636791_43 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002865 276.0
HFD1_k127_1636791_44 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009875 279.0
HFD1_k127_1636791_45 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009817 273.0
HFD1_k127_1636791_46 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000001932 267.0
HFD1_k127_1636791_47 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002207 264.0
HFD1_k127_1636791_48 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000006408 259.0
HFD1_k127_1636791_49 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000312 266.0
HFD1_k127_1636791_5 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 5.545e-290 906.0
HFD1_k127_1636791_50 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000003475 267.0
HFD1_k127_1636791_51 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000002444 246.0
HFD1_k127_1636791_52 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000106 239.0
HFD1_k127_1636791_53 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000003879 231.0
HFD1_k127_1636791_54 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000008253 231.0
HFD1_k127_1636791_55 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000005243 221.0
HFD1_k127_1636791_56 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000007403 224.0
HFD1_k127_1636791_57 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000111 224.0
HFD1_k127_1636791_58 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000000000000000000000000000000000000002119 216.0
HFD1_k127_1636791_59 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000003272 214.0
HFD1_k127_1636791_6 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 3.662e-270 849.0
HFD1_k127_1636791_60 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000259 226.0
HFD1_k127_1636791_61 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000005797 211.0
HFD1_k127_1636791_62 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000221 223.0
HFD1_k127_1636791_64 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000001692 192.0
HFD1_k127_1636791_65 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000000000005321 201.0
HFD1_k127_1636791_66 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.00000000000000000000000000000000000000000000000000002746 194.0
HFD1_k127_1636791_67 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000302 192.0
HFD1_k127_1636791_68 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000006903 187.0
HFD1_k127_1636791_69 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000005153 181.0
HFD1_k127_1636791_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 5.605e-251 786.0
HFD1_k127_1636791_70 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000003892 174.0
HFD1_k127_1636791_71 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000003665 156.0
HFD1_k127_1636791_72 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000372 149.0
HFD1_k127_1636791_73 PFAM CBS domain - - - 0.00000000000000000000000000000000000002192 148.0
HFD1_k127_1636791_74 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000001818 149.0
HFD1_k127_1636791_75 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000003255 147.0
HFD1_k127_1636791_76 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000002856 127.0
HFD1_k127_1636791_77 Thioredoxin-like - - - 0.00000000000000000000000000000002975 131.0
HFD1_k127_1636791_78 cell redox homeostasis K02199 - - 0.0000000000000000000000000000002013 130.0
HFD1_k127_1636791_79 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000006229 126.0
HFD1_k127_1636791_8 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 4.651e-234 731.0
HFD1_k127_1636791_80 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000012 125.0
HFD1_k127_1636791_81 CTP:tRNA cytidylyltransferase activity K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000003811 134.0
HFD1_k127_1636791_82 Protein of unknown function DUF58 - - - 0.00000000000000000000000000003554 130.0
HFD1_k127_1636791_83 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000004993 122.0
HFD1_k127_1636791_84 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000001572 109.0
HFD1_k127_1636791_85 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000001423 108.0
HFD1_k127_1636791_86 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000000002633 106.0
HFD1_k127_1636791_87 Protein of unknown function (DUF2905) - - - 0.000000000000000000001083 96.0
HFD1_k127_1636791_88 PFAM Methylamine - - - 0.0000000000000001937 85.0
HFD1_k127_1636791_89 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000002944 86.0
HFD1_k127_1636791_9 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 7.08e-232 733.0
HFD1_k127_1636791_91 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000006689 79.0
HFD1_k127_1636791_92 protein secretion K03116,K03117 - - 0.000000000005627 69.0
HFD1_k127_1636791_93 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000003799 61.0
HFD1_k127_1636791_94 diguanylate cyclase - - - 0.000000009335 58.0
HFD1_k127_1636791_95 Fibronectin type 3 domain - - - 0.0000003572 61.0
HFD1_k127_1636791_96 Diguanylate cyclase - - - 0.000001487 57.0
HFD1_k127_1636791_97 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000004075 57.0
HFD1_k127_1636791_98 PFAM Rhodanese domain protein - - - 0.00008979 50.0
HFD1_k127_1636791_99 - - - - 0.00009277 45.0
HFD1_k127_1659342_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 572.0
HFD1_k127_1659342_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 557.0
HFD1_k127_1659342_10 - - - - 0.00000000000000004445 83.0
HFD1_k127_1659342_11 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0002123 47.0
HFD1_k127_1659342_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 516.0
HFD1_k127_1659342_3 metal-dependent enzyme K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 293.0
HFD1_k127_1659342_4 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003568 252.0
HFD1_k127_1659342_5 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002064 254.0
HFD1_k127_1659342_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000001447 243.0
HFD1_k127_1659342_7 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000004357 216.0
HFD1_k127_1659342_9 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000004123 115.0
HFD1_k127_1674934_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008305 263.0
HFD1_k127_1674934_1 NmrA-like family - - - 0.0000000000000000000000000000000000004777 144.0
HFD1_k127_1674934_2 phosphorelay signal transduction system - - - 0.00000000006944 66.0
HFD1_k127_1674934_3 - - - - 0.00000002459 60.0
HFD1_k127_1680079_1 Belongs to the ompA family K03286 - - 0.000000000000000000000000006861 120.0
HFD1_k127_1680079_10 bacterial OsmY and nodulation domain - - - 0.0000000008055 66.0
HFD1_k127_1680079_11 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000005419 57.0
HFD1_k127_1680079_2 - - - - 0.000000000000000001421 87.0
HFD1_k127_1680079_3 Protein of unknown function (DUF3309) - - - 0.000000000000000003681 85.0
HFD1_k127_1680079_4 hyperosmotic response K04065 - - 0.0000000000000000237 89.0
HFD1_k127_1680079_5 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000008374 84.0
HFD1_k127_1680079_6 CsbD-like - - - 0.0000000000000002777 80.0
HFD1_k127_1680079_7 periplasmic or secreted lipoprotein K04065 - - 0.00000000005157 68.0
HFD1_k127_1680079_8 CsbD-like - - - 0.00000000008326 66.0
HFD1_k127_1680079_9 - - - - 0.0000000007545 60.0
HFD1_k127_168142_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.316e-236 741.0
HFD1_k127_168142_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.635e-227 741.0
HFD1_k127_168142_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000151 260.0
HFD1_k127_168142_11 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000004693 202.0
HFD1_k127_168142_12 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000007723 207.0
HFD1_k127_168142_13 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000005654 138.0
HFD1_k127_168142_14 ThiS family K03636 - - 0.0000000000000000000000000000000009994 132.0
HFD1_k127_168142_15 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000001268 120.0
HFD1_k127_168142_16 NIL - - - 0.0000000000000000000000000005107 116.0
HFD1_k127_168142_17 cAMP biosynthetic process - - - 0.000008529 59.0
HFD1_k127_168142_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 8e-220 687.0
HFD1_k127_168142_3 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 522.0
HFD1_k127_168142_4 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 521.0
HFD1_k127_168142_5 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 528.0
HFD1_k127_168142_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 454.0
HFD1_k127_168142_7 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 433.0
HFD1_k127_168142_8 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 370.0
HFD1_k127_168142_9 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 299.0
HFD1_k127_1693637_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 3.311e-202 639.0
HFD1_k127_1693637_1 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 573.0
HFD1_k127_1693637_10 - - - - 0.000000000000000000000000000000000000000000000000000000001515 207.0
HFD1_k127_1693637_11 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000003001 200.0
HFD1_k127_1693637_12 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000008703 195.0
HFD1_k127_1693637_13 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000901 190.0
HFD1_k127_1693637_14 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.00000000000000000000000000000000000000000004411 168.0
HFD1_k127_1693637_15 Lysin motif - - - 0.0000000000000000000000000000000001904 145.0
HFD1_k127_1693637_16 O-methyltransferase activity - - - 0.00000000000000000000000000000008519 126.0
HFD1_k127_1693637_17 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000001199 111.0
HFD1_k127_1693637_18 PFAM Protein-tyrosine phosphatase, low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000000001226 115.0
HFD1_k127_1693637_19 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0000000000000000000000001 114.0
HFD1_k127_1693637_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 523.0
HFD1_k127_1693637_20 O-methyltransferase activity - - - 0.000000000000000000000001301 109.0
HFD1_k127_1693637_21 O-methyltransferase activity - - - 0.00000000000000001083 87.0
HFD1_k127_1693637_3 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 421.0
HFD1_k127_1693637_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 424.0
HFD1_k127_1693637_5 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001892 269.0
HFD1_k127_1693637_6 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007453 261.0
HFD1_k127_1693637_7 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001124 256.0
HFD1_k127_1693637_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001539 241.0
HFD1_k127_1693637_9 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000002384 216.0
HFD1_k127_169731_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.285e-243 761.0
HFD1_k127_169731_1 heme-copper terminal oxidase activity K02274 - 1.9.3.1 3.883e-237 743.0
HFD1_k127_169731_10 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 328.0
HFD1_k127_169731_11 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 316.0
HFD1_k127_169731_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009216 293.0
HFD1_k127_169731_13 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000003336 269.0
HFD1_k127_169731_14 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000003759 243.0
HFD1_k127_169731_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000006264 233.0
HFD1_k127_169731_16 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000001204 236.0
HFD1_k127_169731_17 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000003047 227.0
HFD1_k127_169731_18 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000002579 194.0
HFD1_k127_169731_19 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.0000000000000000000000000000000000000000000000000005518 187.0
HFD1_k127_169731_2 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 521.0
HFD1_k127_169731_20 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000002781 199.0
HFD1_k127_169731_21 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000002426 185.0
HFD1_k127_169731_22 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000006877 178.0
HFD1_k127_169731_23 Transcriptional regulator - - - 0.000000000000000000000000000000000000001843 152.0
HFD1_k127_169731_24 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000205 131.0
HFD1_k127_169731_25 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000004846 127.0
HFD1_k127_169731_26 EamA-like transporter family - - - 0.0000000000000000000000000000003161 134.0
HFD1_k127_169731_27 GGDEF domain - - - 0.000000000000000000000000000222 132.0
HFD1_k127_169731_28 Sulfurtransferase TusA - - - 0.00000000000000000000001876 101.0
HFD1_k127_169731_29 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000002274 101.0
HFD1_k127_169731_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 452.0
HFD1_k127_169731_30 Domain of unknown function (DUF4154) - - - 0.000000000000001474 80.0
HFD1_k127_169731_31 Catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge K00574 - 2.1.1.79 0.00000000000003419 74.0
HFD1_k127_169731_32 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000005984 72.0
HFD1_k127_169731_33 Protein involved in formate dehydrogenase formation K02380 - - 0.0000000000008661 71.0
HFD1_k127_169731_34 response regulator K07715 GO:0000156,GO:0000160,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001130,GO:0001150,GO:0001151,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0035556,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000004443 58.0
HFD1_k127_169731_35 Domain of unknown function (DUF4154) - - - 0.00005964 49.0
HFD1_k127_169731_36 photoreceptor activity - - - 0.0006591 45.0
HFD1_k127_169731_37 Methyltransferase domain - - - 0.0006809 48.0
HFD1_k127_169731_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 421.0
HFD1_k127_169731_5 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 398.0
HFD1_k127_169731_6 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 385.0
HFD1_k127_169731_7 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 375.0
HFD1_k127_169731_8 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 413.0
HFD1_k127_169731_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 336.0
HFD1_k127_1714239_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1933.0
HFD1_k127_1714239_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1029.0
HFD1_k127_1714239_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 486.0
HFD1_k127_1714239_11 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 484.0
HFD1_k127_1714239_12 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 488.0
HFD1_k127_1714239_13 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 452.0
HFD1_k127_1714239_14 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 440.0
HFD1_k127_1714239_15 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 441.0
HFD1_k127_1714239_16 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 422.0
HFD1_k127_1714239_17 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 413.0
HFD1_k127_1714239_18 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 411.0
HFD1_k127_1714239_19 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 393.0
HFD1_k127_1714239_2 Heat shock 70 kDa protein K04043 - - 0.0 1013.0
HFD1_k127_1714239_20 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 382.0
HFD1_k127_1714239_21 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 381.0
HFD1_k127_1714239_22 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 372.0
HFD1_k127_1714239_23 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 362.0
HFD1_k127_1714239_24 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 355.0
HFD1_k127_1714239_25 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 354.0
HFD1_k127_1714239_26 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 346.0
HFD1_k127_1714239_27 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 347.0
HFD1_k127_1714239_28 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
HFD1_k127_1714239_29 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
HFD1_k127_1714239_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.092e-244 762.0
HFD1_k127_1714239_30 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 301.0
HFD1_k127_1714239_31 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 291.0
HFD1_k127_1714239_32 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 289.0
HFD1_k127_1714239_33 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 294.0
HFD1_k127_1714239_34 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006579 273.0
HFD1_k127_1714239_35 DJ-1/PfpI family K03152 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000396 262.0
HFD1_k127_1714239_36 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000002269 251.0
HFD1_k127_1714239_37 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000004233 253.0
HFD1_k127_1714239_38 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000114 231.0
HFD1_k127_1714239_39 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001269 235.0
HFD1_k127_1714239_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.662e-232 727.0
HFD1_k127_1714239_40 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000003782 218.0
HFD1_k127_1714239_41 PFAM SEC-C motif K09858 - - 0.000000000000000000000000000000000000000000000000000000000005202 211.0
HFD1_k127_1714239_42 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000000000000000001434 214.0
HFD1_k127_1714239_43 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000001998 209.0
HFD1_k127_1714239_44 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000001073 194.0
HFD1_k127_1714239_45 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000001259 205.0
HFD1_k127_1714239_46 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000003598 183.0
HFD1_k127_1714239_47 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000009373 185.0
HFD1_k127_1714239_48 signal transduction histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000002727 186.0
HFD1_k127_1714239_49 VanZ like family - - - 0.0000000000000000000000000000000000000001072 156.0
HFD1_k127_1714239_5 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.907e-231 729.0
HFD1_k127_1714239_50 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000001056 154.0
HFD1_k127_1714239_51 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000005717 152.0
HFD1_k127_1714239_52 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000000004953 140.0
HFD1_k127_1714239_53 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000002698 127.0
HFD1_k127_1714239_54 - - - - 0.00000000000000000000000000005582 127.0
HFD1_k127_1714239_55 rubredoxin - - - 0.00000000000000000000000009841 106.0
HFD1_k127_1714239_56 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000126 104.0
HFD1_k127_1714239_57 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000001998 97.0
HFD1_k127_1714239_58 Transmembrane protein 62 - - - 0.00000000000000003034 96.0
HFD1_k127_1714239_59 NusG domain II K00805 - 2.5.1.30 0.0000000000000003506 83.0
HFD1_k127_1714239_6 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 8.973e-202 643.0
HFD1_k127_1714239_60 Peptidase family M23 - - - 0.0000000000000005489 85.0
HFD1_k127_1714239_61 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000005225 76.0
HFD1_k127_1714239_62 - - - - 0.0000000000002662 72.0
HFD1_k127_1714239_63 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000003364 69.0
HFD1_k127_1714239_64 integral membrane protein - - - 0.00000002573 63.0
HFD1_k127_1714239_65 PFAM amino acid-binding ACT domain protein - - - 0.00001513 55.0
HFD1_k127_1714239_66 Polyketide cyclase / dehydrase and lipid transport - - - 0.0003244 48.0
HFD1_k127_1714239_7 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 517.0
HFD1_k127_1714239_8 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 506.0
HFD1_k127_1714239_9 TIGRFAM arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 509.0
HFD1_k127_1736803_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 411.0
HFD1_k127_1736803_1 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 330.0
HFD1_k127_1736803_2 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000009914 135.0
HFD1_k127_1736803_3 - - - - 0.00000000002823 68.0
HFD1_k127_1811334_0 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 486.0
HFD1_k127_1811334_1 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000001445 136.0
HFD1_k127_1811334_2 - - - - 0.0000000000000000000002238 96.0
HFD1_k127_1811334_3 helix_turn_helix, Lux Regulon K14979 - - 0.000000001012 70.0
HFD1_k127_1816181_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 492.0
HFD1_k127_1816181_1 HMGL-like K01666 - 4.1.3.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 409.0
HFD1_k127_1816181_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 398.0
HFD1_k127_1816181_3 - - - - 0.00000000000000000000000000000000000000000000000000244 187.0
HFD1_k127_1816181_4 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000005498 162.0
HFD1_k127_1816181_5 protein complex oligomerization - - - 0.000000000000000000001027 103.0
HFD1_k127_1816181_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000005786 59.0
HFD1_k127_1816181_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000006275 57.0
HFD1_k127_1816181_8 PAS PAC sensor signal transduction histidine kinase - - - 0.000001395 51.0
HFD1_k127_1819348_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 6.174e-253 796.0
HFD1_k127_1819348_1 AMP-binding enzyme C-terminal domain - - - 3.991e-200 631.0
HFD1_k127_1819348_10 Putative beta-barrel porin 2 - - - 0.000000000000000002362 98.0
HFD1_k127_1819348_2 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 490.0
HFD1_k127_1819348_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 402.0
HFD1_k127_1819348_4 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 383.0
HFD1_k127_1819348_5 Formyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 318.0
HFD1_k127_1819348_6 AAA domain K08252 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 292.0
HFD1_k127_1819348_7 Polysaccharide deacetylase K11931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001547 259.0
HFD1_k127_1819348_8 Transcription termination factor nusG - - - 0.000000000000000000000000000000000000000000001481 173.0
HFD1_k127_1819348_9 Phosphopantetheine attachment site - - - 0.00000000000000000007866 91.0
HFD1_k127_188804_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.24e-219 696.0
HFD1_k127_188804_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 469.0
HFD1_k127_188804_10 Phage integrase SAM-like domain - - - 0.00000000003504 70.0
HFD1_k127_188804_11 CsbD-like - - - 0.00000000003861 64.0
HFD1_k127_188804_2 cell wall hydrolase K01449 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007161 276.0
HFD1_k127_188804_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000002224 218.0
HFD1_k127_188804_4 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000001308 203.0
HFD1_k127_188804_5 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000223 186.0
HFD1_k127_188804_6 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000000001255 132.0
HFD1_k127_188804_7 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000005275 96.0
HFD1_k127_188804_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000006958 70.0
HFD1_k127_2018802_0 GTP-binding GTPase Middle Region K03665 - - 8.563e-195 622.0
HFD1_k127_2018802_1 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 597.0
HFD1_k127_2018802_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 581.0
HFD1_k127_2018802_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 462.0
HFD1_k127_2018802_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 436.0
HFD1_k127_2018802_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 301.0
HFD1_k127_2018802_6 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000001665 220.0
HFD1_k127_2018802_7 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.000000000000000000000000000002293 127.0
HFD1_k127_2153713_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1448.0
HFD1_k127_2153713_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.271e-283 883.0
HFD1_k127_2153713_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 455.0
HFD1_k127_2153713_11 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 454.0
HFD1_k127_2153713_12 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 454.0
HFD1_k127_2153713_13 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 432.0
HFD1_k127_2153713_14 glucose sorbosone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 435.0
HFD1_k127_2153713_15 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 410.0
HFD1_k127_2153713_16 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 396.0
HFD1_k127_2153713_17 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 383.0
HFD1_k127_2153713_18 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 376.0
HFD1_k127_2153713_19 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 361.0
HFD1_k127_2153713_2 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 3.226e-230 716.0
HFD1_k127_2153713_20 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 350.0
HFD1_k127_2153713_21 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 343.0
HFD1_k127_2153713_22 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 370.0
HFD1_k127_2153713_23 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 323.0
HFD1_k127_2153713_24 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 321.0
HFD1_k127_2153713_25 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 286.0
HFD1_k127_2153713_26 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 282.0
HFD1_k127_2153713_27 Evidence 4 Homologs of previously reported genes of K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001625 286.0
HFD1_k127_2153713_28 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000165 277.0
HFD1_k127_2153713_29 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001603 261.0
HFD1_k127_2153713_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.436e-195 617.0
HFD1_k127_2153713_30 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001657 234.0
HFD1_k127_2153713_31 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000002019 215.0
HFD1_k127_2153713_32 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000007369 201.0
HFD1_k127_2153713_33 Glyoxalase-like domain K07032 - - 0.0000000000000000000000000000000000000000000000000000003086 196.0
HFD1_k127_2153713_34 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000000000000000001629 191.0
HFD1_k127_2153713_35 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000007839 191.0
HFD1_k127_2153713_36 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000001421 185.0
HFD1_k127_2153713_37 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000001261 154.0
HFD1_k127_2153713_38 Cytochrome P460 - - - 0.0000000000000000000000000000000000000005205 155.0
HFD1_k127_2153713_39 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000001889 149.0
HFD1_k127_2153713_4 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008375 590.0
HFD1_k127_2153713_40 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000008827 153.0
HFD1_k127_2153713_41 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000002113 124.0
HFD1_k127_2153713_42 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000006715 135.0
HFD1_k127_2153713_43 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000000003549 122.0
HFD1_k127_2153713_44 - - - - 0.0000000000000000000000000001691 120.0
HFD1_k127_2153713_45 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000000000000233 116.0
HFD1_k127_2153713_46 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.000000000000000000000001667 112.0
HFD1_k127_2153713_47 PFAM Transglycosylase-associated protein - - - 0.000000000000000000000133 98.0
HFD1_k127_2153713_48 - - - - 0.00000000000000000005663 95.0
HFD1_k127_2153713_49 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000009036 98.0
HFD1_k127_2153713_5 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 587.0
HFD1_k127_2153713_50 ORF6N domain - - - 0.000000000000000001075 87.0
HFD1_k127_2153713_51 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000002315 85.0
HFD1_k127_2153713_52 phosphorelay signal transduction system - - - 0.000000000000000422 83.0
HFD1_k127_2153713_53 part of a sulfur-relay system K11179 - - 0.000000000000002088 76.0
HFD1_k127_2153713_54 mercury ion transmembrane transporter activity K07213 - - 0.00000000000000533 76.0
HFD1_k127_2153713_55 Alanine-zipper, major outer membrane lipoprotein - - - 0.0000000000002841 74.0
HFD1_k127_2153713_56 - - - - 0.00000000003419 66.0
HFD1_k127_2153713_57 Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000004471 68.0
HFD1_k127_2153713_58 PFAM Lytic transglycosylase catalytic - - - 0.0000000004876 68.0
HFD1_k127_2153713_59 - - - - 0.0000000006756 61.0
HFD1_k127_2153713_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 522.0
HFD1_k127_2153713_61 part of a sulfur-relay system K11179 - - 0.000000101 54.0
HFD1_k127_2153713_62 - - - - 0.00001217 53.0
HFD1_k127_2153713_7 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 517.0
HFD1_k127_2153713_8 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 516.0
HFD1_k127_2153713_9 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 469.0
HFD1_k127_2211245_0 PFAM Glycosyl transferase family 2 K07011,K20444 - - 1.352e-228 723.0
HFD1_k127_2211245_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 529.0
HFD1_k127_2211245_10 - - - - 0.00000004314 55.0
HFD1_k127_2211245_11 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00001968 56.0
HFD1_k127_2211245_2 PFAM ATP adenylyltransferase K00988 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 338.0
HFD1_k127_2211245_3 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 320.0
HFD1_k127_2211245_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 307.0
HFD1_k127_2211245_5 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 333.0
HFD1_k127_2211245_6 PFAM phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000119 286.0
HFD1_k127_2211245_7 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001205 282.0
HFD1_k127_2211245_8 arylsulfatase A - - - 0.000000000000000000000009453 118.0
HFD1_k127_2211245_9 Cna B domain protein - - - 0.000000000000002007 90.0
HFD1_k127_224859_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1258.0
HFD1_k127_224859_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.526e-214 672.0
HFD1_k127_224859_10 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 324.0
HFD1_k127_224859_11 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 314.0
HFD1_k127_224859_12 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000375 280.0
HFD1_k127_224859_13 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000000000000000008013 195.0
HFD1_k127_224859_14 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000000000000000000964 171.0
HFD1_k127_224859_16 heat shock protein binding - - - 0.000000000000000000000000000000000001892 149.0
HFD1_k127_224859_17 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00000000000000000000000000000000001071 142.0
HFD1_k127_224859_18 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000003241 125.0
HFD1_k127_224859_19 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000003418 104.0
HFD1_k127_224859_2 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 1.997e-205 651.0
HFD1_k127_224859_21 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000001799 94.0
HFD1_k127_224859_22 Regulatory protein, FmdB family - - - 0.000000000000000000257 89.0
HFD1_k127_224859_24 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000004405 79.0
HFD1_k127_224859_25 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000001731 55.0
HFD1_k127_224859_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 8.538e-204 642.0
HFD1_k127_224859_4 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 439.0
HFD1_k127_224859_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 372.0
HFD1_k127_224859_6 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 372.0
HFD1_k127_224859_7 Cys Met metabolism K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 362.0
HFD1_k127_224859_8 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 348.0
HFD1_k127_224859_9 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 333.0
HFD1_k127_2301644_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 415.0
HFD1_k127_2301644_1 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 295.0
HFD1_k127_2301644_3 Glycosyl transferases group 1 - - - 0.0000000000000004459 80.0
HFD1_k127_2433713_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1225.0
HFD1_k127_2433713_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1159.0
HFD1_k127_2433713_10 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 362.0
HFD1_k127_2433713_11 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 371.0
HFD1_k127_2433713_12 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 348.0
HFD1_k127_2433713_13 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 320.0
HFD1_k127_2433713_14 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 316.0
HFD1_k127_2433713_15 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 314.0
HFD1_k127_2433713_16 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
HFD1_k127_2433713_17 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004353 278.0
HFD1_k127_2433713_18 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001249 267.0
HFD1_k127_2433713_19 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001191 246.0
HFD1_k127_2433713_2 Telomere recombination K04656 - - 5.387e-250 797.0
HFD1_k127_2433713_20 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000002244 231.0
HFD1_k127_2433713_21 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000005977 197.0
HFD1_k127_2433713_22 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000009957 170.0
HFD1_k127_2433713_23 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000124 171.0
HFD1_k127_2433713_24 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000001318 163.0
HFD1_k127_2433713_25 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000002678 156.0
HFD1_k127_2433713_26 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000000000005812 153.0
HFD1_k127_2433713_27 calcium- and calmodulin-responsive adenylate cyclase activity K01179,K01406 - 3.2.1.4,3.4.24.40 0.00000000000000000000000000000005395 139.0
HFD1_k127_2433713_28 RibD C-terminal domain - - - 0.0000000000000000000000000000003211 126.0
HFD1_k127_2433713_29 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000001641 124.0
HFD1_k127_2433713_3 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 589.0
HFD1_k127_2433713_30 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000001014 100.0
HFD1_k127_2433713_31 PQQ-like domain - - - 0.000000000000000008571 96.0
HFD1_k127_2433713_32 Putative zinc- or iron-chelating domain K06940 - - 0.00002731 51.0
HFD1_k127_2433713_33 - - - - 0.0004444 50.0
HFD1_k127_2433713_34 Transposase IS200 like - - - 0.00073 44.0
HFD1_k127_2433713_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 487.0
HFD1_k127_2433713_5 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 463.0
HFD1_k127_2433713_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 455.0
HFD1_k127_2433713_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 417.0
HFD1_k127_2433713_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 409.0
HFD1_k127_2433713_9 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 402.0
HFD1_k127_2446764_0 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000489 244.0
HFD1_k127_2446764_1 Diguanylate cyclase with GAF sensor - - - 0.00000000000000000000000000000000000000000001446 177.0
HFD1_k127_2446764_2 Chaperone protein dnaJ 72 - - - 0.000000003587 68.0
HFD1_k127_2456604_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 8.344e-311 975.0
HFD1_k127_2456604_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 552.0
HFD1_k127_2456604_10 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000001227 130.0
HFD1_k127_2456604_11 cellulose binding - - - 0.0000000000000000000000000001544 131.0
HFD1_k127_2456604_12 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000004497 119.0
HFD1_k127_2456604_13 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000006977 122.0
HFD1_k127_2456604_14 response to copper ion - - - 0.00000000000000000000002374 111.0
HFD1_k127_2456604_15 Regulatory protein RecX K03565 - - 0.000000000000006979 80.0
HFD1_k127_2456604_16 Protein of unknown function (DUF1566) - - - 0.00000001923 67.0
HFD1_k127_2456604_17 ATP synthase, subunit b - - - 0.0000001514 57.0
HFD1_k127_2456604_18 response regulator K07664 - - 0.00006547 45.0
HFD1_k127_2456604_19 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00007137 51.0
HFD1_k127_2456604_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 502.0
HFD1_k127_2456604_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 500.0
HFD1_k127_2456604_4 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000004562 221.0
HFD1_k127_2456604_5 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000004446 189.0
HFD1_k127_2456604_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000001275 168.0
HFD1_k127_2456604_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000000004053 159.0
HFD1_k127_2456604_8 CHRD domain - - - 0.000000000000000000000000000000000000003183 151.0
HFD1_k127_2456604_9 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000000000000000002009 133.0
HFD1_k127_2475808_0 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 515.0
HFD1_k127_2475808_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 336.0
HFD1_k127_2475808_10 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.00000000000000000146 89.0
HFD1_k127_2475808_11 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000001583 84.0
HFD1_k127_2475808_12 Domain of unknown function DUF302 - - - 0.0000000000000615 75.0
HFD1_k127_2475808_13 sequence-specific DNA binding - - - 0.0000000002832 64.0
HFD1_k127_2475808_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003686 268.0
HFD1_k127_2475808_3 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000404 223.0
HFD1_k127_2475808_4 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000000000000000000000000000001862 212.0
HFD1_k127_2475808_5 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000001129 157.0
HFD1_k127_2475808_6 membrane - - - 0.0000000000000000000000000000000000283 138.0
HFD1_k127_2475808_7 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000006312 131.0
HFD1_k127_2475808_8 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000466 105.0
HFD1_k127_2475808_9 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000002164 97.0
HFD1_k127_2498853_0 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 413.0
HFD1_k127_2498853_1 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000006211 250.0
HFD1_k127_2498853_2 Calcineurin-like phosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000003098 224.0
HFD1_k127_2498853_3 part of a sulfur-relay system K11179 - - 0.00000000000000000000000000002542 119.0
HFD1_k127_2498853_4 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000001907 100.0
HFD1_k127_2498853_5 - - - - 0.000000000000000001054 86.0
HFD1_k127_2498853_6 - - - - 0.0000006437 54.0
HFD1_k127_2498853_7 - - - - 0.00004089 51.0
HFD1_k127_254312_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1627.0
HFD1_k127_254312_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 465.0
HFD1_k127_254312_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 436.0
HFD1_k127_254312_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07789,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 321.0
HFD1_k127_254312_4 Chemotaxis sensory transducer K03406 - - 0.000000000008229 68.0
HFD1_k127_254312_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00004094 54.0
HFD1_k127_2580084_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 4192.0
HFD1_k127_2580084_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 559.0
HFD1_k127_2580084_10 Protein of unknown function (DUF1456) - - - 0.000000000000000000000000000003459 121.0
HFD1_k127_2580084_11 RNA recognition motif - - - 0.000000000000000000000007612 105.0
HFD1_k127_2580084_12 TPR Domain containing protein K12600 - - 0.000000000000000000001695 105.0
HFD1_k127_2580084_13 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000008951 85.0
HFD1_k127_2580084_14 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000009189 80.0
HFD1_k127_2580084_15 pyridoxamine 5'-phosphate K07005 - - 0.0000000000002422 74.0
HFD1_k127_2580084_16 PFAM histidine kinase, HAMP region domain protein K03406 - - 0.000000000001109 71.0
HFD1_k127_2580084_17 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000155 69.0
HFD1_k127_2580084_18 Nitroreductase family - - - 0.000000006949 61.0
HFD1_k127_2580084_19 Nucleotidyl transferase K00963 - 2.7.7.9 0.00007439 46.0
HFD1_k127_2580084_2 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007182 276.0
HFD1_k127_2580084_20 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00009159 48.0
HFD1_k127_2580084_21 PFAM ferredoxin thioredoxin reductase beta - - - 0.0007961 48.0
HFD1_k127_2580084_3 Beta-lactamase enzyme family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000001878 221.0
HFD1_k127_2580084_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000008439 210.0
HFD1_k127_2580084_5 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000000000001079 215.0
HFD1_k127_2580084_6 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000005688 183.0
HFD1_k127_2580084_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000003153 183.0
HFD1_k127_2580084_8 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000009363 173.0
HFD1_k127_2580084_9 - - - - 0.00000000000000000000000000000000000000000001008 166.0
HFD1_k127_2610127_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1558.0
HFD1_k127_2610127_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 556.0
HFD1_k127_2610127_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 410.0
HFD1_k127_2610127_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 394.0
HFD1_k127_2610127_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 320.0
HFD1_k127_2610127_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001539 272.0
HFD1_k127_2610127_6 superoxide reductase activity K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000006209 208.0
HFD1_k127_2610127_7 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K08244 - 2.7.9.4 0.00000000000000000000000000000000001519 144.0
HFD1_k127_2610127_8 YtkA-like - - - 0.000000000000000000000000001262 116.0
HFD1_k127_2610127_9 Belongs to the ompA family K03640 - - 0.0000000000000001933 85.0
HFD1_k127_2610260_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.829e-263 828.0
HFD1_k127_2610260_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 2.641e-213 675.0
HFD1_k127_2610260_10 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000001003 149.0
HFD1_k127_2610260_11 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000004242 134.0
HFD1_k127_2610260_12 - - - - 0.000000000000000000000000000001746 136.0
HFD1_k127_2610260_13 GlcNAc-PI de-N-acetylase K01463,K20444 - - 0.00000000000000000000009799 110.0
HFD1_k127_2610260_14 Uncharacterized conserved protein (DUF2304) - - - 0.0000000001131 66.0
HFD1_k127_2610260_15 COG0438 Glycosyltransferase - - - 0.0000000001311 66.0
HFD1_k127_2610260_16 - - - - 0.0000001824 58.0
HFD1_k127_2610260_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 578.0
HFD1_k127_2610260_3 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 460.0
HFD1_k127_2610260_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 338.0
HFD1_k127_2610260_5 Bacterial type II and III secretion system protein K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000655 306.0
HFD1_k127_2610260_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000007439 224.0
HFD1_k127_2610260_7 group 2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000001022 215.0
HFD1_k127_2610260_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000005166 211.0
HFD1_k127_2610260_9 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000001351 201.0
HFD1_k127_2633452_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 5.073e-195 625.0
HFD1_k127_2633452_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 561.0
HFD1_k127_2633452_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 556.0
HFD1_k127_2633452_3 phosphosulfolactate synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 425.0
HFD1_k127_2633452_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 406.0
HFD1_k127_2633452_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 351.0
HFD1_k127_2633452_6 Na+ dependent nucleoside transporter C-terminus K03317 - - 0.000000000000000001901 86.0
HFD1_k127_2633452_7 Na dependent nucleoside transporter K03317 - - 0.000000000000000002255 92.0
HFD1_k127_2633452_8 Aldehyde dehydrogenase family K22187 - - 0.000000001281 59.0
HFD1_k127_2635249_0 Protein of unknown function, DUF255 K06888 - - 1.398e-253 797.0
HFD1_k127_2635249_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 630.0
HFD1_k127_2635249_10 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000009075 173.0
HFD1_k127_2635249_11 methyltransferase activity - - - 0.00000000000000000000000000000000000000001072 160.0
HFD1_k127_2635249_12 Response regulator receiver - - - 0.00000000000000000000000008114 111.0
HFD1_k127_2635249_13 Low affinity iron permease - - - 0.00000000000000000000004299 102.0
HFD1_k127_2635249_14 PFAM Integrase core domain - - - 0.000000000000005082 76.0
HFD1_k127_2635249_15 - - - - 0.0000000000001255 72.0
HFD1_k127_2635249_16 small integral membrane protein - - - 0.0000000000001855 72.0
HFD1_k127_2635249_17 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000009751 69.0
HFD1_k127_2635249_18 NADPH-dependent FMN reductase - - - 0.00000000001001 66.0
HFD1_k127_2635249_2 metal ion transmembrane transporter activity K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 518.0
HFD1_k127_2635249_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 421.0
HFD1_k127_2635249_4 Flavodoxin-like fold K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004349 264.0
HFD1_k127_2635249_5 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000001009 238.0
HFD1_k127_2635249_6 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000001659 204.0
HFD1_k127_2635249_7 Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000004172 184.0
HFD1_k127_2635249_8 PFAM Integrase core domain - - - 0.00000000000000000000000000000000000000000000004928 176.0
HFD1_k127_2635249_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000008402 178.0
HFD1_k127_2720591_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 430.0
HFD1_k127_2720591_1 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000004219 178.0
HFD1_k127_2720591_2 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000003695 142.0
HFD1_k127_2720591_3 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000005607 133.0
HFD1_k127_2720591_4 - - - - 0.000000000000000000000000000008896 137.0
HFD1_k127_2720591_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000003809 92.0
HFD1_k127_2720591_7 SpoVT / AbrB like domain - - - 0.0000000000000003083 81.0
HFD1_k127_2720591_8 cellulose binding K01179 - 3.2.1.4 0.00000000000002617 87.0
HFD1_k127_2720591_9 Belongs to the 'phage' integrase family - - - 0.0001312 47.0
HFD1_k127_2760840_0 4Fe-4S dicluster domain - - - 2.729e-300 927.0
HFD1_k127_2760840_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 8.404e-263 827.0
HFD1_k127_2760840_10 pfam psp1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002304 253.0
HFD1_k127_2760840_11 PFAM HPP family K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000001175 236.0
HFD1_k127_2760840_12 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000466 231.0
HFD1_k127_2760840_13 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000002318 236.0
HFD1_k127_2760840_14 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000002923 205.0
HFD1_k127_2760840_15 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000000000002465 170.0
HFD1_k127_2760840_16 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000007044 160.0
HFD1_k127_2760840_17 - - - - 0.000000000000000000000000000000000000000002344 160.0
HFD1_k127_2760840_18 SMART HNH nuclease K07451 - - 0.000000000000000000000000000000000000004447 148.0
HFD1_k127_2760840_19 Pyridoxamine 5'-phosphate oxidase like - - - 0.00000000000000000000000000000000000001406 149.0
HFD1_k127_2760840_2 ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 610.0
HFD1_k127_2760840_20 PFAM CBS domain - - - 0.00000000000000000000000000000002079 133.0
HFD1_k127_2760840_21 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000002262 117.0
HFD1_k127_2760840_22 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000004073 113.0
HFD1_k127_2760840_23 Protein of unknown function (DUF507) - - - 0.000000000000000000000000004223 112.0
HFD1_k127_2760840_24 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000001589 105.0
HFD1_k127_2760840_25 4Fe-4S binding domain - - - 0.0000000000000000006816 87.0
HFD1_k127_2760840_26 Protein of unknown function (DUF1460) - - - 0.00000001499 64.0
HFD1_k127_2760840_3 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 563.0
HFD1_k127_2760840_4 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 486.0
HFD1_k127_2760840_5 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 474.0
HFD1_k127_2760840_6 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 430.0
HFD1_k127_2760840_7 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 378.0
HFD1_k127_2760840_8 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 354.0
HFD1_k127_2760840_9 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 307.0
HFD1_k127_2765103_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.243e-274 857.0
HFD1_k127_2765103_1 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 2.962e-239 747.0
HFD1_k127_2765103_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 391.0
HFD1_k127_2765103_11 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 382.0
HFD1_k127_2765103_12 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 369.0
HFD1_k127_2765103_13 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 355.0
HFD1_k127_2765103_14 HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide K12138,K12139,K15829 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 339.0
HFD1_k127_2765103_15 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 297.0
HFD1_k127_2765103_16 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005158 275.0
HFD1_k127_2765103_17 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006788 274.0
HFD1_k127_2765103_18 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000001058 246.0
HFD1_k127_2765103_19 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000001436 237.0
HFD1_k127_2765103_2 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 5.861e-196 631.0
HFD1_k127_2765103_20 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000009089 236.0
HFD1_k127_2765103_21 PFAM NADH Ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000002139 222.0
HFD1_k127_2765103_22 Bacterial regulatory proteins, crp family - - - 0.000000000000000000000000000000000000000000000008399 180.0
HFD1_k127_2765103_23 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000002022 145.0
HFD1_k127_2765103_24 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000337 144.0
HFD1_k127_2765103_25 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000002898 138.0
HFD1_k127_2765103_26 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.00000000000000000000013 102.0
HFD1_k127_2765103_27 Type II secretion system protein B K02451 - - 0.0000000000000006692 86.0
HFD1_k127_2765103_28 - - - - 0.000000000001409 69.0
HFD1_k127_2765103_3 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 614.0
HFD1_k127_2765103_30 - - - - 0.0000004944 52.0
HFD1_k127_2765103_4 NAD(P)H-binding K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 539.0
HFD1_k127_2765103_5 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 518.0
HFD1_k127_2765103_6 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 482.0
HFD1_k127_2765103_7 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 463.0
HFD1_k127_2765103_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 413.0
HFD1_k127_2765103_9 sugar transferase K00996 - 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 404.0
HFD1_k127_278229_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.146e-256 801.0
HFD1_k127_278229_1 Endoribonuclease that initiates mRNA decay K18682 - - 9.968e-211 668.0
HFD1_k127_278229_10 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 348.0
HFD1_k127_278229_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 336.0
HFD1_k127_278229_12 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 338.0
HFD1_k127_278229_13 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 340.0
HFD1_k127_278229_14 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 338.0
HFD1_k127_278229_15 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 311.0
HFD1_k127_278229_16 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000001398 237.0
HFD1_k127_278229_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000257 221.0
HFD1_k127_278229_18 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000006925 203.0
HFD1_k127_278229_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000008644 202.0
HFD1_k127_278229_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.047e-203 637.0
HFD1_k127_278229_20 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000004291 169.0
HFD1_k127_278229_21 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000002821 144.0
HFD1_k127_278229_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000839 93.0
HFD1_k127_278229_23 - K06039,K07092 - - 0.00000005589 60.0
HFD1_k127_278229_24 SNARE associated Golgi protein K03975 - - 0.000001216 50.0
HFD1_k127_278229_25 PFAM LemA family K03744 - - 0.00001184 51.0
HFD1_k127_278229_3 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 501.0
HFD1_k127_278229_4 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 456.0
HFD1_k127_278229_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 432.0
HFD1_k127_278229_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 433.0
HFD1_k127_278229_7 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 408.0
HFD1_k127_278229_8 K transport systems K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 375.0
HFD1_k127_278229_9 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 362.0
HFD1_k127_2810537_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 327.0
HFD1_k127_2810537_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
HFD1_k127_2810537_2 Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005387 247.0
HFD1_k127_2810537_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000001817 106.0
HFD1_k127_2810537_4 anti-sigma regulatory factor K04757 - 2.7.11.1 0.0000000000000000000008003 100.0
HFD1_k127_2810537_5 STAS domain K04749 - - 0.000000000000000000005627 96.0
HFD1_k127_2810537_6 MlaD protein K02067,K06192 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016043,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0120009 - 0.000000000001044 79.0
HFD1_k127_2810537_7 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00005698 53.0
HFD1_k127_2817335_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 408.0
HFD1_k127_2817335_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000073 174.0
HFD1_k127_2817335_2 Alpha/beta hydrolase family K15357 - 3.5.1.106 0.00000000000000000000000000000000000000000001765 172.0
HFD1_k127_2817335_3 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000000003225 123.0
HFD1_k127_2817335_4 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000001632 124.0
HFD1_k127_2817335_5 Alpha Beta K06889 - - 0.000000000000000000006433 93.0
HFD1_k127_2817335_6 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000001508 98.0
HFD1_k127_2817335_7 Recombinase K06400 - - 0.00001551 48.0
HFD1_k127_2835606_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 595.0
HFD1_k127_2835606_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 325.0
HFD1_k127_2835606_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000003523 177.0
HFD1_k127_2835606_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000001152 93.0
HFD1_k127_2835606_4 Protein of unknown function (DUF721) - - - 0.0000000265 61.0
HFD1_k127_2855375_0 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 486.0
HFD1_k127_2855375_1 PFAM Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 447.0
HFD1_k127_2855375_10 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000006148 103.0
HFD1_k127_2855375_11 SMART Rhodanese domain protein - - - 0.00000000000000000002106 94.0
HFD1_k127_2855375_12 - - - - 0.0000000000000000001332 93.0
HFD1_k127_2855375_13 iron-regulated protein - - - 0.00000000000000002416 85.0
HFD1_k127_2855375_14 Universal stress protein family - - - 0.000000001292 65.0
HFD1_k127_2855375_15 Histidine kinase - - - 0.000000002081 59.0
HFD1_k127_2855375_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000001111 59.0
HFD1_k127_2855375_17 - - - - 0.000004726 55.0
HFD1_k127_2855375_18 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00001934 48.0
HFD1_k127_2855375_19 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.00004038 53.0
HFD1_k127_2855375_2 protein histidine kinase activity K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005152 253.0
HFD1_k127_2855375_3 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000000000000000000000001617 229.0
HFD1_k127_2855375_4 SMART Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000000000000004997 201.0
HFD1_k127_2855375_5 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000005446 171.0
HFD1_k127_2855375_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000004322 161.0
HFD1_k127_2855375_7 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000004685 152.0
HFD1_k127_2855375_8 - - - - 0.00000000000000000000000000000004829 128.0
HFD1_k127_2855375_9 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000007349 106.0
HFD1_k127_2895812_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.21e-261 825.0
HFD1_k127_2895812_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 4.026e-233 738.0
HFD1_k127_2895812_10 cobalamin-transporting ATPase activity K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001336 293.0
HFD1_k127_2895812_11 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 253.0
HFD1_k127_2895812_12 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004512 254.0
HFD1_k127_2895812_13 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000314 248.0
HFD1_k127_2895812_14 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000003908 250.0
HFD1_k127_2895812_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001409 249.0
HFD1_k127_2895812_16 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000006301 222.0
HFD1_k127_2895812_17 O-methyltransferase family 3 - - - 0.00000000000000000000000000000000000000000000000000000000007478 212.0
HFD1_k127_2895812_18 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000008069 208.0
HFD1_k127_2895812_19 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000139 194.0
HFD1_k127_2895812_2 Seven times multi-haem cytochrome CxxCH - - - 6.524e-198 623.0
HFD1_k127_2895812_20 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000004793 185.0
HFD1_k127_2895812_21 SURF4 family K15977 - - 0.0000000000000000000000000000000000000000002736 161.0
HFD1_k127_2895812_22 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000001216 149.0
HFD1_k127_2895812_23 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000002349 143.0
HFD1_k127_2895812_24 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000002249 131.0
HFD1_k127_2895812_25 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000776 136.0
HFD1_k127_2895812_26 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000007573 130.0
HFD1_k127_2895812_27 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000002294 130.0
HFD1_k127_2895812_28 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000001115 118.0
HFD1_k127_2895812_29 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000001798 100.0
HFD1_k127_2895812_3 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 451.0
HFD1_k127_2895812_31 Belongs to the sulfur carrier protein TusA family - - - 0.000000000004646 68.0
HFD1_k127_2895812_33 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000001183 71.0
HFD1_k127_2895812_34 DsrE/DsrF-like family K07235 - - 0.0000005297 56.0
HFD1_k127_2895812_35 PFAM Positive regulator of sigma(E), RseC MucC K03803 - - 0.0000005482 58.0
HFD1_k127_2895812_36 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000001671 55.0
HFD1_k127_2895812_37 helix_turn_helix, Lux Regulon - - - 0.000007295 55.0
HFD1_k127_2895812_39 Rdx family K07401 - - 0.00003421 49.0
HFD1_k127_2895812_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 370.0
HFD1_k127_2895812_5 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 364.0
HFD1_k127_2895812_6 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 368.0
HFD1_k127_2895812_7 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 361.0
HFD1_k127_2895812_8 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008591 370.0
HFD1_k127_2895812_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 319.0
HFD1_k127_2901094_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1091.0
HFD1_k127_2901094_1 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 0.0 1055.0
HFD1_k127_2901094_10 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 331.0
HFD1_k127_2901094_11 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 325.0
HFD1_k127_2901094_12 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 295.0
HFD1_k127_2901094_13 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 285.0
HFD1_k127_2901094_14 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000004234 218.0
HFD1_k127_2901094_15 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000002694 188.0
HFD1_k127_2901094_16 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000001069 182.0
HFD1_k127_2901094_17 Glycoside hydrolase family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000262 181.0
HFD1_k127_2901094_19 response regulator - - - 0.0000000000000000000000000000000002659 144.0
HFD1_k127_2901094_2 ABC transporter K06020 - 3.6.3.25 1.361e-307 948.0
HFD1_k127_2901094_20 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000001578 105.0
HFD1_k127_2901094_21 3-beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.00000000000000000000001348 112.0
HFD1_k127_2901094_22 Homologous to orf229 gp Streptococcus thermophilus bacteriophage Sfi19 gi 9632919 ref NP_049948.1 - - - 0.0000000000000597 79.0
HFD1_k127_2901094_25 - - - - 0.0001622 52.0
HFD1_k127_2901094_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 556.0
HFD1_k127_2901094_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 512.0
HFD1_k127_2901094_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 528.0
HFD1_k127_2901094_6 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 480.0
HFD1_k127_2901094_7 PAS domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 478.0
HFD1_k127_2901094_8 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 447.0
HFD1_k127_2901094_9 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 332.0
HFD1_k127_3062021_0 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 499.0
HFD1_k127_3062021_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000001111 160.0
HFD1_k127_3062021_2 - - - - 0.0000000000000000000000004234 111.0
HFD1_k127_3062021_3 Cytidylate kinase-like family K00945 - 2.7.4.25 0.0000000000000001803 85.0
HFD1_k127_3062021_4 - - - - 0.00001403 53.0
HFD1_k127_3062021_5 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0006046 44.0
HFD1_k127_3071660_0 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 327.0
HFD1_k127_3101085_0 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 471.0
HFD1_k127_3101085_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 376.0
HFD1_k127_3101085_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002774 287.0
HFD1_k127_3101085_3 SWI complex, BAF60b domains - - - 0.00000000000000000000000000001554 119.0
HFD1_k127_3101085_4 PFAM Transposase IS200-like - - - 0.00000004114 58.0
HFD1_k127_3101085_5 - - - - 0.000006165 53.0
HFD1_k127_3101085_6 Protein of unknown function (DUF2934) - - - 0.0001407 48.0
HFD1_k127_3130753_0 Patatin-like phospholipase - - - 0.000000000000000000000001316 106.0
HFD1_k127_3150434_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.902e-201 634.0
HFD1_k127_3150434_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 8.481e-197 620.0
HFD1_k127_3150434_10 AMP binding - - - 0.00000000000000000000000000000000000000001814 156.0
HFD1_k127_3150434_11 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000003847 151.0
HFD1_k127_3150434_12 Transcriptional regulator - - - 0.000000000000000000000000000000001022 138.0
HFD1_k127_3150434_13 - - - - 0.000000000000000000000000000000002062 132.0
HFD1_k127_3150434_14 - - - - 0.000000000837 64.0
HFD1_k127_3150434_15 - - - - 0.00000126 54.0
HFD1_k127_3150434_16 domain protein - - - 0.00004764 52.0
HFD1_k127_3150434_17 type II secretion system protein E - - - 0.000104 48.0
HFD1_k127_3150434_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 558.0
HFD1_k127_3150434_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 310.0
HFD1_k127_3150434_4 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002862 273.0
HFD1_k127_3150434_5 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000483 244.0
HFD1_k127_3150434_6 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000001413 236.0
HFD1_k127_3150434_7 PFAM MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000002886 216.0
HFD1_k127_3150434_8 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000001981 205.0
HFD1_k127_3150434_9 molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000000000005347 199.0
HFD1_k127_3194931_0 Elongation factor SelB, winged helix K03833 - - 4.969e-212 675.0
HFD1_k127_3194931_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 539.0
HFD1_k127_3194931_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 461.0
HFD1_k127_3194931_3 Ecdysteroid kinase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 445.0
HFD1_k127_3194931_4 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 326.0
HFD1_k127_3194931_5 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 325.0
HFD1_k127_3194931_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 306.0
HFD1_k127_3194931_7 NTPase - - - 0.00000000000000000000000000000000000005493 148.0
HFD1_k127_3194931_8 Uncharacterised protein family (UPF0158) - - - 0.000000001555 66.0
HFD1_k127_3194931_9 Domain of unknown function (DUF4388) - - - 0.0001189 52.0
HFD1_k127_3229191_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 6.572e-313 974.0
HFD1_k127_3229191_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.45e-273 856.0
HFD1_k127_3229191_10 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 500.0
HFD1_k127_3229191_11 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 499.0
HFD1_k127_3229191_12 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 495.0
HFD1_k127_3229191_13 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 474.0
HFD1_k127_3229191_14 (ABC) transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 436.0
HFD1_k127_3229191_15 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 428.0
HFD1_k127_3229191_16 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 429.0
HFD1_k127_3229191_17 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 399.0
HFD1_k127_3229191_18 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 388.0
HFD1_k127_3229191_19 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 379.0
HFD1_k127_3229191_2 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 9.344e-242 760.0
HFD1_k127_3229191_20 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 314.0
HFD1_k127_3229191_21 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005765 257.0
HFD1_k127_3229191_22 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000002078 230.0
HFD1_k127_3229191_23 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000006354 223.0
HFD1_k127_3229191_24 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000005642 226.0
HFD1_k127_3229191_25 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000004859 208.0
HFD1_k127_3229191_26 AMP binding K03499,K06149 - - 0.0000000000000000000000000000000000002568 144.0
HFD1_k127_3229191_27 heat shock protein binding - - - 0.0000000000000000000000000000000004909 143.0
HFD1_k127_3229191_28 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000000000006989 121.0
HFD1_k127_3229191_29 Stringent starvation protein B K09985 - - 0.00000000000000000000000000005136 121.0
HFD1_k127_3229191_3 Cytochrome c554 and c-prime - - - 1.883e-234 733.0
HFD1_k127_3229191_30 copG family - - - 0.0000000000000000972 80.0
HFD1_k127_3229191_32 - - - - 0.00000000000001223 76.0
HFD1_k127_3229191_33 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000001582 59.0
HFD1_k127_3229191_34 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00002042 46.0
HFD1_k127_3229191_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.333e-226 708.0
HFD1_k127_3229191_5 Aminotransferase class-III K01845 - 5.4.3.8 7.735e-202 635.0
HFD1_k127_3229191_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 2.337e-195 620.0
HFD1_k127_3229191_7 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 552.0
HFD1_k127_3229191_8 response to heat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 556.0
HFD1_k127_3229191_9 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 552.0
HFD1_k127_3256298_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 528.0
HFD1_k127_3256298_1 Belongs to the 'phage' integrase family - - - 0.00000000000000001094 83.0
HFD1_k127_3256298_3 Antibiotic biosynthesis monooxygenase K01056 GO:0003674,GO:0003824 3.1.1.29 0.0000001886 55.0
HFD1_k127_3256298_5 Belongs to the 'phage' integrase family K03733,K14059 - - 0.0007058 43.0
HFD1_k127_3312248_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 3.242e-229 727.0
HFD1_k127_3312248_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 422.0
HFD1_k127_3312248_10 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000000000002347 169.0
HFD1_k127_3312248_11 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000009229 159.0
HFD1_k127_3312248_12 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000001093 159.0
HFD1_k127_3312248_13 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000005439 110.0
HFD1_k127_3312248_14 - - - - 0.00000000000002779 77.0
HFD1_k127_3312248_15 PFAM Nitrate reductase gamma subunit - - - 0.00000001883 65.0
HFD1_k127_3312248_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 369.0
HFD1_k127_3312248_3 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 339.0
HFD1_k127_3312248_4 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 330.0
HFD1_k127_3312248_5 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 320.0
HFD1_k127_3312248_6 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 321.0
HFD1_k127_3312248_7 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 316.0
HFD1_k127_3312248_8 COG3335 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000629 203.0
HFD1_k127_3312248_9 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000248 201.0
HFD1_k127_3330359_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 588.0
HFD1_k127_3330359_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 367.0
HFD1_k127_3330359_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000001404 72.0
HFD1_k127_3330359_11 PFAM Rubrerythrin - - - 0.00000000001041 71.0
HFD1_k127_3330359_13 Short C-terminal domain K08982 - - 0.00003883 50.0
HFD1_k127_3330359_14 radical SAM domain protein - - - 0.0000532 49.0
HFD1_k127_3330359_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 327.0
HFD1_k127_3330359_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 333.0
HFD1_k127_3330359_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003597 252.0
HFD1_k127_3330359_5 DGC domain - - - 0.000000000000000000000000000000000000000000000000000006022 194.0
HFD1_k127_3330359_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000001554 128.0
HFD1_k127_3330359_7 DsrC like protein K11179 - - 0.0000000000000000000000004645 109.0
HFD1_k127_3330359_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000002196 86.0
HFD1_k127_3330398_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1027.0
HFD1_k127_3330398_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 555.0
HFD1_k127_3330398_10 Transposase IS200 like - - - 0.00000000000000000000000000000000000707 141.0
HFD1_k127_3330398_11 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.000000000000000000000000001919 115.0
HFD1_k127_3330398_12 sulfur carrier activity - - - 0.000000000000000000305 89.0
HFD1_k127_3330398_13 Universal stress protein - - - 0.0000000000000009189 88.0
HFD1_k127_3330398_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 542.0
HFD1_k127_3330398_3 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 416.0
HFD1_k127_3330398_4 PFAM Radical SAM K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 402.0
HFD1_k127_3330398_5 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 379.0
HFD1_k127_3330398_6 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 366.0
HFD1_k127_3330398_7 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 300.0
HFD1_k127_3330398_8 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000003471 228.0
HFD1_k127_3330398_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000002918 206.0
HFD1_k127_3338004_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1052.0
HFD1_k127_3338004_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1050.0
HFD1_k127_3338004_10 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 411.0
HFD1_k127_3338004_11 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005064 273.0
HFD1_k127_3338004_12 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000007016 237.0
HFD1_k127_3338004_13 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000006035 215.0
HFD1_k127_3338004_14 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000001516 179.0
HFD1_k127_3338004_15 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000001204 151.0
HFD1_k127_3338004_16 Rhodanese domain protein - - - 0.000000000000000000000000004081 113.0
HFD1_k127_3338004_17 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000001173 115.0
HFD1_k127_3338004_18 general secretion pathway protein G K02456 - - 0.0000000001042 61.0
HFD1_k127_3338004_19 Secretin and TonB N terminus short domain K02666 - - 0.0002845 49.0
HFD1_k127_3338004_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 7.284e-288 918.0
HFD1_k127_3338004_3 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.712e-247 770.0
HFD1_k127_3338004_4 Sigma54 specific transcriptional regulator, Fis family - - - 1.449e-214 679.0
HFD1_k127_3338004_5 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 572.0
HFD1_k127_3338004_6 all-trans-retinol 13,14-reductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 567.0
HFD1_k127_3338004_7 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 515.0
HFD1_k127_3338004_8 Chromate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 492.0
HFD1_k127_3338004_9 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 465.0
HFD1_k127_3341832_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 9.738e-200 641.0
HFD1_k127_3341832_1 FAD binding domain K00278 - 1.4.3.16 1.176e-194 621.0
HFD1_k127_3341832_10 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K01256,K02563,K02652,K08776,K12132 - 2.4.1.227,2.7.11.1,3.4.11.2 0.000007925 53.0
HFD1_k127_3341832_2 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 550.0
HFD1_k127_3341832_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 472.0
HFD1_k127_3341832_4 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 475.0
HFD1_k127_3341832_5 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 356.0
HFD1_k127_3341832_6 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001035 294.0
HFD1_k127_3341832_7 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000294 248.0
HFD1_k127_3341832_8 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.00000000000000000000000000000000000000001206 157.0
HFD1_k127_3341832_9 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000003267 55.0
HFD1_k127_3347977_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001778 257.0
HFD1_k127_3347977_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000005436 235.0
HFD1_k127_3347977_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000004062 190.0
HFD1_k127_3347977_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000002083 105.0
HFD1_k127_3347977_4 PFAM Tetratricopeptide repeat - - - 0.000000001935 67.0
HFD1_k127_3347977_5 Phosphoesterase family - - - 0.00001867 56.0
HFD1_k127_33960_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1058.0
HFD1_k127_33960_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 540.0
HFD1_k127_33960_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000002249 146.0
HFD1_k127_33960_3 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000007173 104.0
HFD1_k127_33960_4 Sigma-54 interaction domain K00575 - 2.1.1.80 0.000000000000000000000008842 104.0
HFD1_k127_33960_5 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000004666 94.0
HFD1_k127_33960_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000005388 96.0
HFD1_k127_33960_7 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000009603 87.0
HFD1_k127_33960_8 Belongs to the peptidase M48B family K03799 - - 0.0000004257 52.0
HFD1_k127_33960_9 ATP-binding region ATPase domain protein - - - 0.00001355 48.0
HFD1_k127_349301_0 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007948 274.0
HFD1_k127_349301_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001448 250.0
HFD1_k127_349301_2 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000000000001075 234.0
HFD1_k127_349301_3 - - - - 0.00000000000001334 80.0
HFD1_k127_349301_4 - - - - 0.000000002987 63.0
HFD1_k127_3503843_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 574.0
HFD1_k127_3503843_1 - - - - 0.00000000000000000000000009597 111.0
HFD1_k127_3503843_2 Protein of unknown function (DUF3309) - - - 0.00000000000000000007219 89.0
HFD1_k127_3503843_4 CsbD-like - - - 0.00000000000227 70.0
HFD1_k127_3503843_5 Protein of unknown function (DUF3096) - - - 0.000000001222 59.0
HFD1_k127_3503843_6 CsbD-like - - - 0.0000002931 52.0
HFD1_k127_3509007_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 367.0
HFD1_k127_3509007_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004834 274.0
HFD1_k127_3509007_2 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000002483 226.0
HFD1_k127_3509007_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000002254 124.0
HFD1_k127_3509007_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000001086 88.0
HFD1_k127_3509007_6 Predicted membrane protein (DUF2318) - - - 0.00000000002106 71.0
HFD1_k127_3555409_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 1.772e-281 889.0
HFD1_k127_3555409_1 PFAM Type II secretion system protein E K02454 - - 1.413e-199 633.0
HFD1_k127_3555409_10 reductase - - - 0.00000000000000000000000000000000000000000000000000003385 194.0
HFD1_k127_3555409_11 - - - - 0.0000000000000000000000000000000000000000003624 164.0
HFD1_k127_3555409_12 NosL - - - 0.0000000000000000000000000000000000000000004582 162.0
HFD1_k127_3555409_13 protein transport across the cell outer membrane K02452,K02463 - - 0.0000000000000000000000000000000000006184 150.0
HFD1_k127_3555409_14 Type II secretion system (T2SS), protein J K02459 - - 0.00000000000000000000002159 109.0
HFD1_k127_3555409_15 - - - - 0.00000000000000000000021 108.0
HFD1_k127_3555409_16 NADPH-dependent FMN reductase - - - 0.000000000000000000004035 93.0
HFD1_k127_3555409_17 Prokaryotic N-terminal methylation motif K02457 - - 0.00000000000000000008395 95.0
HFD1_k127_3555409_19 - - - - 0.00000000000005313 75.0
HFD1_k127_3555409_2 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 539.0
HFD1_k127_3555409_20 Type II secretion system (T2SS), protein K K02460 - - 0.000000003016 68.0
HFD1_k127_3555409_21 Prokaryotic N-terminal methylation motif K02458 - - 0.0000001403 58.0
HFD1_k127_3555409_3 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 380.0
HFD1_k127_3555409_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 323.0
HFD1_k127_3555409_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 313.0
HFD1_k127_3555409_6 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 301.0
HFD1_k127_3555409_7 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 261.0
HFD1_k127_3555409_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000001688 213.0
HFD1_k127_3555409_9 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000009362 206.0
HFD1_k127_3699494_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.0 1378.0
HFD1_k127_3699494_1 DHHA2 domain K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 557.0
HFD1_k127_3699494_10 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000007918 145.0
HFD1_k127_3699494_11 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000004675 139.0
HFD1_k127_3699494_12 Ankyrin repeat-containing protein K21440 - - 0.00000000000000000000000004349 115.0
HFD1_k127_3699494_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000009633 104.0
HFD1_k127_3699494_14 - - - - 0.00000000000000000000003002 100.0
HFD1_k127_3699494_15 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000008255 80.0
HFD1_k127_3699494_16 - - - - 0.0000000000000005399 82.0
HFD1_k127_3699494_17 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000001603 79.0
HFD1_k127_3699494_18 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000252 67.0
HFD1_k127_3699494_19 SNARE associated Golgi protein - - - 0.0000000001006 62.0
HFD1_k127_3699494_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 496.0
HFD1_k127_3699494_20 - - - - 0.000000000414 61.0
HFD1_k127_3699494_21 Rhodanese Homology Domain - - - 0.00000397 49.0
HFD1_k127_3699494_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 492.0
HFD1_k127_3699494_4 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 404.0
HFD1_k127_3699494_5 phosphoglycolate phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 332.0
HFD1_k127_3699494_6 flavin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 302.0
HFD1_k127_3699494_7 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 305.0
HFD1_k127_3699494_8 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001919 252.0
HFD1_k127_3699494_9 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000004669 229.0
HFD1_k127_370429_0 Belongs to the peptidase S8 family - - - 8.594e-208 662.0
HFD1_k127_370429_1 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 363.0
HFD1_k127_370429_2 Outer membrane efflux protein - - - 0.000000000000000004949 98.0
HFD1_k127_370429_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.00000004399 63.0
HFD1_k127_370429_4 PEP-CTERM motif - - - 0.0003061 43.0
HFD1_k127_3741381_0 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000001736 165.0
HFD1_k127_3741381_1 anaerobic respiration - - - 0.0000000000000000000000000000007541 129.0
HFD1_k127_3741381_2 PFAM blue (type 1) copper domain protein - - - 0.00000004294 59.0
HFD1_k127_3752025_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.298e-300 942.0
HFD1_k127_3752025_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 549.0
HFD1_k127_3752025_10 Tetratricopeptide repeat - - - 0.0000000000000000007755 95.0
HFD1_k127_3752025_11 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000003198 99.0
HFD1_k127_3752025_12 manually curated - - - 0.00000000001504 66.0
HFD1_k127_3752025_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 505.0
HFD1_k127_3752025_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 354.0
HFD1_k127_3752025_4 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 296.0
HFD1_k127_3752025_5 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000629 264.0
HFD1_k127_3752025_6 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000008402 195.0
HFD1_k127_3752025_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000001503 124.0
HFD1_k127_3752025_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000002136 128.0
HFD1_k127_3752025_9 TIGRFAM Polymorphic membrane protein, Chlamydia - - - 0.0000000000000000004946 102.0
HFD1_k127_3784789_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.744e-226 713.0
HFD1_k127_3784789_1 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 387.0
HFD1_k127_3784789_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 331.0
HFD1_k127_3784789_3 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000002934 127.0
HFD1_k127_3784789_5 Transposase IS200 like - - - 0.000000006422 61.0
HFD1_k127_3784789_6 copG family - - - 0.0000000214 55.0
HFD1_k127_3784789_7 Transposase K07491 - - 0.00000005854 55.0
HFD1_k127_3905997_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 371.0
HFD1_k127_3905997_1 DNA integration - - - 0.00000000000000000000000000000000000000714 155.0
HFD1_k127_3905997_2 DNA photolyase activity - - - 0.000000000000000000000000007638 115.0
HFD1_k127_3905997_3 - - - - 0.000000000000000000000000971 108.0
HFD1_k127_3905997_4 phage terminase small subunit - - - 0.000000000000000000000006445 104.0
HFD1_k127_3905997_5 radical SAM domain protein - - - 0.000000000000000002917 87.0
HFD1_k127_3905997_6 DNA integration - - - 0.0000000000000002978 81.0
HFD1_k127_4051965_0 PLD-like domain K06131 - - 1.522e-207 653.0
HFD1_k127_4051965_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000005351 248.0
HFD1_k127_4051965_10 - - - - 0.0001568 48.0
HFD1_k127_4051965_11 P-type ATPase K17686,K19597 GO:0000041,GO:0000139,GO:0000166,GO:0003674,GO:0003824,GO:0004008,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005794,GO:0005802,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006874,GO:0006875,GO:0006878,GO:0008144,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0012505,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015677,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019725,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030554,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0031984,GO:0032553,GO:0032555,GO:0032559,GO:0032588,GO:0034220,GO:0035434,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0043682,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051208,GO:0051234,GO:0051235,GO:0055065,GO:0055070,GO:0055074,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0065007,GO:0065008,GO:0071944,GO:0072503,GO:0072507,GO:0090662,GO:0097159,GO:0097367,GO:0097708,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098791,GO:0099131,GO:0099132,GO:1901265,GO:1901363 3.6.3.54 0.0003521 45.0
HFD1_k127_4051965_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000597 219.0
HFD1_k127_4051965_3 COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family - - - 0.0000000000000000000000000000000000000000000002917 168.0
HFD1_k127_4051965_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000008747 154.0
HFD1_k127_4051965_5 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000002195 149.0
HFD1_k127_4051965_6 AI-2E family transporter - - - 0.000000000000000000000001502 117.0
HFD1_k127_4051965_7 COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family - - - 0.00000000000000000009918 89.0
HFD1_k127_4051965_9 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000221 49.0
HFD1_k127_4056375_0 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 2.683e-206 661.0
HFD1_k127_4056375_1 PFAM Type II secretion system protein E K02283,K03609 - - 1.494e-202 639.0
HFD1_k127_4056375_10 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000002983 182.0
HFD1_k127_4056375_11 aspartic-type endopeptidase activity K02278,K02654 - 3.4.23.43 0.000000000000000000000000000000000000006654 151.0
HFD1_k127_4056375_12 anti-sigma regulatory factor, serine threonine protein kinase - - - 0.00000000000000000000000001176 114.0
HFD1_k127_4056375_13 isomerase activity - - - 0.00000000000000000000000001597 113.0
HFD1_k127_4056375_14 PFAM TadE family protein - - - 0.0000000000000000000000001577 111.0
HFD1_k127_4056375_15 STAS domain K04749 - - 0.00000000000000000000000427 105.0
HFD1_k127_4056375_16 TadE-like protein - - - 0.0000000000000000685 86.0
HFD1_k127_4056375_18 Flp Fap pilin component K02651 - - 0.0000000000009751 69.0
HFD1_k127_4056375_19 OsmC-like protein - - - 0.00000004088 55.0
HFD1_k127_4056375_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 602.0
HFD1_k127_4056375_20 TonB C terminal - - - 0.000002442 60.0
HFD1_k127_4056375_21 - - - - 0.00001225 51.0
HFD1_k127_4056375_22 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00007729 48.0
HFD1_k127_4056375_23 STAS domain K04749 - - 0.0006817 46.0
HFD1_k127_4056375_24 Flp/Fap pilin component - - - 0.0008996 43.0
HFD1_k127_4056375_3 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 452.0
HFD1_k127_4056375_4 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 362.0
HFD1_k127_4056375_5 PFAM type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 325.0
HFD1_k127_4056375_6 TIGRFAM Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 294.0
HFD1_k127_4056375_7 type II secretion system protein K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 289.0
HFD1_k127_4056375_8 SAF K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001105 272.0
HFD1_k127_4056375_9 belongs to the iron- containing alcohol dehydrogenase family K04072 - 1.1.1.1,1.2.1.10 0.000000000000000000000000000000000000000000000000004397 187.0
HFD1_k127_4141456_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 419.0
HFD1_k127_4141456_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 304.0
HFD1_k127_4141456_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000003914 133.0
HFD1_k127_4141456_3 - K07487 - - 0.0000000002637 63.0
HFD1_k127_4165751_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 1.455e-278 879.0
HFD1_k127_4165751_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 583.0
HFD1_k127_4165751_10 epimerase dehydratase K07071 - - 0.000000000000000004119 87.0
HFD1_k127_4165751_11 PFAM regulatory protein ArsR K22043 - - 0.000000000001003 72.0
HFD1_k127_4165751_12 belongs to the sigma-70 factor family - - - 0.000000000001943 74.0
HFD1_k127_4165751_13 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000002248 56.0
HFD1_k127_4165751_14 - - - - 0.00000008369 57.0
HFD1_k127_4165751_16 Methyltransferase K15256 - - 0.0000004698 52.0
HFD1_k127_4165751_17 Predicted metal-binding protein (DUF2284) - - - 0.0000006188 53.0
HFD1_k127_4165751_18 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000001984 53.0
HFD1_k127_4165751_19 PFAM Methyltransferase type 11 - - - 0.0006341 44.0
HFD1_k127_4165751_2 PFAM Bile acid sodium symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 292.0
HFD1_k127_4165751_3 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001485 273.0
HFD1_k127_4165751_4 NOG31153 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004563 270.0
HFD1_k127_4165751_5 TIGRFAM phosphodiesterase, MJ0936 - - - 0.0000000000000000000000000000000000000000000000000000000000002619 219.0
HFD1_k127_4165751_6 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000007164 120.0
HFD1_k127_4165751_7 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000003489 118.0
HFD1_k127_4165751_8 phosphorelay signal transduction system - - - 0.00000000000000000000001042 104.0
HFD1_k127_4165751_9 Rhodanese Homology Domain - - - 0.0000000000000000000002236 102.0
HFD1_k127_4208512_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1083.0
HFD1_k127_4208512_1 PFAM Acetyl-CoA hydrolase transferase K18122 - - 7.797e-293 910.0
HFD1_k127_4208512_10 Sodium:solute symporter family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 619.0
HFD1_k127_4208512_11 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 579.0
HFD1_k127_4208512_12 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 498.0
HFD1_k127_4208512_13 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 462.0
HFD1_k127_4208512_14 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 452.0
HFD1_k127_4208512_15 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 448.0
HFD1_k127_4208512_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 437.0
HFD1_k127_4208512_17 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 434.0
HFD1_k127_4208512_18 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 432.0
HFD1_k127_4208512_19 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 400.0
HFD1_k127_4208512_2 Molecular chaperone. Has ATPase activity K04079 - - 1.354e-267 837.0
HFD1_k127_4208512_20 formate dehydrogenase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 379.0
HFD1_k127_4208512_21 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 381.0
HFD1_k127_4208512_22 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 327.0
HFD1_k127_4208512_23 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 319.0
HFD1_k127_4208512_24 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
HFD1_k127_4208512_25 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 299.0
HFD1_k127_4208512_26 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001686 300.0
HFD1_k127_4208512_27 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000001534 271.0
HFD1_k127_4208512_28 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000126 254.0
HFD1_k127_4208512_29 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003417 249.0
HFD1_k127_4208512_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 4.02e-251 789.0
HFD1_k127_4208512_30 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006296 247.0
HFD1_k127_4208512_31 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000374 260.0
HFD1_k127_4208512_32 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002184 234.0
HFD1_k127_4208512_33 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000009139 226.0
HFD1_k127_4208512_34 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000433 229.0
HFD1_k127_4208512_35 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000001369 222.0
HFD1_k127_4208512_36 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000002194 214.0
HFD1_k127_4208512_37 nucleoside-triphosphate diphosphatase activity K06287 - - 0.0000000000000000000000000000000000000000000000002195 183.0
HFD1_k127_4208512_38 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000004087 154.0
HFD1_k127_4208512_39 Hydrogenase expression formation protein K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000006061 133.0
HFD1_k127_4208512_4 PD-(D/E)XK nuclease superfamily - - - 7.47e-247 799.0
HFD1_k127_4208512_40 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000002188 134.0
HFD1_k127_4208512_41 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000009713 127.0
HFD1_k127_4208512_42 Protein of unknown function, DUF485 - - - 0.000000000000000000000000005599 113.0
HFD1_k127_4208512_43 SMART Cold shock protein K03704 - - 0.00000000000000000000000001349 109.0
HFD1_k127_4208512_44 metalloendopeptidase activity - - - 0.00000000000000000000000596 113.0
HFD1_k127_4208512_45 Protein of unknown function (DUF1189) - - - 0.00000000000000000002184 100.0
HFD1_k127_4208512_46 carbon dioxide binding K04653 - - 0.0000000000000000001984 91.0
HFD1_k127_4208512_47 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000003452 75.0
HFD1_k127_4208512_48 Protein of unknown function (DUF2892) - - - 0.000000000002954 72.0
HFD1_k127_4208512_49 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000009469 71.0
HFD1_k127_4208512_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 4.571e-242 755.0
HFD1_k127_4208512_50 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000002014 68.0
HFD1_k127_4208512_51 PFAM Tetratricopeptide repeat - - - 0.00007291 53.0
HFD1_k127_4208512_52 Protein of unknown function (DUF2892) - - - 0.0002641 49.0
HFD1_k127_4208512_6 Sugar (and other) transporter K03446 - - 7.052e-233 730.0
HFD1_k127_4208512_7 Belongs to the helicase family. UvrD subfamily - - - 5.049e-224 730.0
HFD1_k127_4208512_8 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 2.392e-217 696.0
HFD1_k127_4208512_9 ABC-type antimicrobial peptide transport system, permease component K02004 - - 6.079e-195 614.0
HFD1_k127_4585782_0 glucan 1,4-alpha-glucosidase activity - - - 3.375e-231 733.0
HFD1_k127_4585782_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 417.0
HFD1_k127_4585782_10 - - - - 0.00003818 53.0
HFD1_k127_4585782_2 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 354.0
HFD1_k127_4585782_3 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 296.0
HFD1_k127_4585782_4 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005239 279.0
HFD1_k127_4585782_5 helicase activity - - - 0.0000000000000000002666 90.0
HFD1_k127_4585782_8 Peptidase family M48 - - - 0.00000018 63.0
HFD1_k127_4585782_9 helicase activity - - - 0.000002525 49.0
HFD1_k127_4642804_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1212.0
HFD1_k127_4642804_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 549.0
HFD1_k127_4642804_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 366.0
HFD1_k127_4642804_3 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 327.0
HFD1_k127_4642804_4 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000003223 220.0
HFD1_k127_4642804_5 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000008576 214.0
HFD1_k127_4642804_6 COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family - - - 0.0000000000000000000000002176 106.0
HFD1_k127_4642804_7 acetyltransferase - - - 0.0000000001744 63.0
HFD1_k127_4642804_8 - - - - 0.00000002945 57.0
HFD1_k127_4642804_9 Copper resistance protein CopZ K07213 - - 0.00001736 49.0
HFD1_k127_4643002_0 Sigma-54 interaction domain - - - 8.126e-240 753.0
HFD1_k127_4643002_1 Phosphoglycerate kinase K00927 - 2.7.2.3 2.384e-196 621.0
HFD1_k127_4643002_10 - - - - 0.000000000000000000000001164 111.0
HFD1_k127_4643002_2 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 550.0
HFD1_k127_4643002_3 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 543.0
HFD1_k127_4643002_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 418.0
HFD1_k127_4643002_5 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 311.0
HFD1_k127_4643002_6 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000787 271.0
HFD1_k127_4643002_7 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000003557 242.0
HFD1_k127_4643002_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000006232 205.0
HFD1_k127_4643002_9 MGS-like domain - - - 0.000000000000000000000000000000000000000000000005739 180.0
HFD1_k127_4723226_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 603.0
HFD1_k127_4723226_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000006867 194.0
HFD1_k127_4723226_2 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000002616 193.0
HFD1_k127_4723226_3 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000001038 186.0
HFD1_k127_4723226_4 Sigma-54 interaction domain K06714 - - 0.0000000000000000000000048 103.0
HFD1_k127_475428_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.698e-215 679.0
HFD1_k127_475428_1 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 7.605e-212 672.0
HFD1_k127_475428_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001758 240.0
HFD1_k127_475428_11 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000007006 223.0
HFD1_k127_475428_12 TIGRFAM phosphodiesterase, MJ0936 - - - 0.0000000000000000000000000000000000000000000000000000002957 202.0
HFD1_k127_475428_13 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000002592 147.0
HFD1_k127_475428_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000004119 148.0
HFD1_k127_475428_15 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000002569 143.0
HFD1_k127_475428_16 3'-5' exonuclease - - - 0.00000000000000000000000000001414 128.0
HFD1_k127_475428_17 cell redox homeostasis - - - 0.0000000000000000000001334 100.0
HFD1_k127_475428_18 PFAM Thioredoxin K03671 - - 0.0000000000000000000001932 101.0
HFD1_k127_475428_19 - - - - 0.00000002807 57.0
HFD1_k127_475428_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 8.695e-202 631.0
HFD1_k127_475428_20 Tetratricopeptide repeat - - - 0.0000002007 58.0
HFD1_k127_475428_21 - - - - 0.00005494 51.0
HFD1_k127_475428_22 Tetratricopeptide repeat - - - 0.00009889 48.0
HFD1_k127_475428_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 587.0
HFD1_k127_475428_4 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 541.0
HFD1_k127_475428_5 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 497.0
HFD1_k127_475428_6 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 454.0
HFD1_k127_475428_7 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 435.0
HFD1_k127_475428_8 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 390.0
HFD1_k127_475428_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001877 247.0
HFD1_k127_4755008_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1695.0
HFD1_k127_4755008_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.606e-283 878.0
HFD1_k127_4755008_10 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 423.0
HFD1_k127_4755008_11 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 396.0
HFD1_k127_4755008_12 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 386.0
HFD1_k127_4755008_13 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 385.0
HFD1_k127_4755008_14 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 370.0
HFD1_k127_4755008_15 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 362.0
HFD1_k127_4755008_16 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 355.0
HFD1_k127_4755008_17 Putative Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 340.0
HFD1_k127_4755008_18 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 300.0
HFD1_k127_4755008_19 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000003805 271.0
HFD1_k127_4755008_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 2.665e-203 639.0
HFD1_k127_4755008_20 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001028 272.0
HFD1_k127_4755008_21 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000002908 259.0
HFD1_k127_4755008_22 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004876 247.0
HFD1_k127_4755008_23 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000005451 240.0
HFD1_k127_4755008_24 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000008763 235.0
HFD1_k127_4755008_25 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000005502 231.0
HFD1_k127_4755008_26 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000009078 217.0
HFD1_k127_4755008_27 Peptidase S24-like K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000001805 206.0
HFD1_k127_4755008_28 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000001464 204.0
HFD1_k127_4755008_29 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000007101 201.0
HFD1_k127_4755008_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.939e-198 625.0
HFD1_k127_4755008_30 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000002406 201.0
HFD1_k127_4755008_31 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000876 196.0
HFD1_k127_4755008_32 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000007614 195.0
HFD1_k127_4755008_33 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000002305 191.0
HFD1_k127_4755008_34 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000001811 169.0
HFD1_k127_4755008_35 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000103 153.0
HFD1_k127_4755008_36 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000004098 140.0
HFD1_k127_4755008_37 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000007328 144.0
HFD1_k127_4755008_38 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000002529 128.0
HFD1_k127_4755008_39 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000119 112.0
HFD1_k127_4755008_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 4.507e-197 621.0
HFD1_k127_4755008_40 Transcriptional regulator, arsR family - - - 0.000000000000000000000003112 105.0
HFD1_k127_4755008_41 protein conserved in bacteria - - - 0.000000000000000000001028 98.0
HFD1_k127_4755008_42 - - - - 0.00000000000000000005136 94.0
HFD1_k127_4755008_43 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000002182 83.0
HFD1_k127_4755008_44 - - - - 0.0000000000000004459 80.0
HFD1_k127_4755008_45 SMART helix-turn-helix domain protein K15539 - - 0.0000000001515 71.0
HFD1_k127_4755008_46 toxin-antitoxin pair type II binding - - - 0.00009889 48.0
HFD1_k127_4755008_47 nucleic acid-binding protein contains PIN domain - - - 0.0003573 49.0
HFD1_k127_4755008_5 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 494.0
HFD1_k127_4755008_6 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 487.0
HFD1_k127_4755008_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 483.0
HFD1_k127_4755008_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 468.0
HFD1_k127_4755008_9 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 421.0
HFD1_k127_4809917_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 471.0
HFD1_k127_4809917_1 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000001601 187.0
HFD1_k127_4809917_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000001198 129.0
HFD1_k127_4809917_3 UPF0391 membrane protein - - - 0.000000000003169 68.0
HFD1_k127_4809917_4 methyltransferase - - - 0.0000003431 52.0
HFD1_k127_4851325_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 558.0
HFD1_k127_4851325_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 549.0
HFD1_k127_4851325_10 Transposase IS200 like - - - 0.00000000000000077 80.0
HFD1_k127_4851325_11 Protein of unknown function (DUF1264) - - - 0.00000000000001519 80.0
HFD1_k127_4851325_13 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000007552 59.0
HFD1_k127_4851325_14 Protein of unknown function DUF116 K09729 - - 0.000004737 57.0
HFD1_k127_4851325_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 496.0
HFD1_k127_4851325_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 430.0
HFD1_k127_4851325_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000009265 246.0
HFD1_k127_4851325_5 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000000000002124 226.0
HFD1_k127_4851325_6 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000004975 218.0
HFD1_k127_4851325_7 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000002316 222.0
HFD1_k127_4851325_8 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000005947 172.0
HFD1_k127_4851325_9 PQ loop repeat K15383 - - 0.0000000000000000000002154 98.0
HFD1_k127_4893381_0 reductase, alpha subunit K00394 - 1.8.99.2 1e-323 1000.0
HFD1_k127_4893381_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 1.635e-309 962.0
HFD1_k127_4893381_10 FAD dependent oxidoreductase K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 580.0
HFD1_k127_4893381_11 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 545.0
HFD1_k127_4893381_12 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 531.0
HFD1_k127_4893381_13 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 516.0
HFD1_k127_4893381_14 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 520.0
HFD1_k127_4893381_15 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 407.0
HFD1_k127_4893381_16 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 405.0
HFD1_k127_4893381_17 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 399.0
HFD1_k127_4893381_18 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 395.0
HFD1_k127_4893381_19 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 394.0
HFD1_k127_4893381_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 1.321e-306 957.0
HFD1_k127_4893381_20 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 402.0
HFD1_k127_4893381_21 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 385.0
HFD1_k127_4893381_22 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 354.0
HFD1_k127_4893381_23 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 344.0
HFD1_k127_4893381_24 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 325.0
HFD1_k127_4893381_25 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 306.0
HFD1_k127_4893381_26 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 297.0
HFD1_k127_4893381_27 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 286.0
HFD1_k127_4893381_28 PFAM DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 286.0
HFD1_k127_4893381_29 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 284.0
HFD1_k127_4893381_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.926e-289 903.0
HFD1_k127_4893381_30 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000001199 263.0
HFD1_k127_4893381_31 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000043 257.0
HFD1_k127_4893381_32 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004587 246.0
HFD1_k127_4893381_33 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000005975 235.0
HFD1_k127_4893381_34 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000006914 236.0
HFD1_k127_4893381_35 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007326 235.0
HFD1_k127_4893381_36 reductase, beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000002262 229.0
HFD1_k127_4893381_37 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000006196 224.0
HFD1_k127_4893381_38 2Fe-2S -binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000002039 218.0
HFD1_k127_4893381_39 Metal-dependent phosphohydrolase K06950 - - 0.00000000000000000000000000000000000000000000000000000000000007054 219.0
HFD1_k127_4893381_4 Sulfatase K01130 - 3.1.6.1 1.142e-272 850.0
HFD1_k127_4893381_40 ATP cone domain - - - 0.000000000000000000000000000000000000000000000000000000003342 207.0
HFD1_k127_4893381_41 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000006636 189.0
HFD1_k127_4893381_42 photosystem II stabilization K02237 - - 0.000000000000000000000000000000000000000000000000003362 193.0
HFD1_k127_4893381_43 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000003948 192.0
HFD1_k127_4893381_44 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000198 180.0
HFD1_k127_4893381_45 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.0000000000000000000000000000000000000003432 154.0
HFD1_k127_4893381_46 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000000000000006939 149.0
HFD1_k127_4893381_47 - - - - 0.00000000000000000000000000004873 119.0
HFD1_k127_4893381_48 Protein of unknown function DUF134 - - - 0.00000000000000000000000006704 109.0
HFD1_k127_4893381_49 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000007026 109.0
HFD1_k127_4893381_5 ABC transporter K15738 - - 3.069e-237 749.0
HFD1_k127_4893381_50 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000000001448 103.0
HFD1_k127_4893381_51 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.0000000001163 64.0
HFD1_k127_4893381_52 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000002229 61.0
HFD1_k127_4893381_53 Thiol-disulfide isomerase and thioredoxins - - - 0.00000002747 58.0
HFD1_k127_4893381_55 Thioredoxin-like - - - 0.00001897 49.0
HFD1_k127_4893381_6 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 3.638e-227 710.0
HFD1_k127_4893381_7 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.191e-210 663.0
HFD1_k127_4893381_8 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 8.668e-204 640.0
HFD1_k127_4893381_9 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 588.0
HFD1_k127_4898011_0 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000003102 226.0
HFD1_k127_4898011_1 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000001253 200.0
HFD1_k127_4898011_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000001305 123.0
HFD1_k127_4898011_3 Cytochrome c K08738 - - 0.0000000000000000000003111 101.0
HFD1_k127_4898011_4 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000007283 79.0
HFD1_k127_4898011_5 Universal stress protein family - - - 0.00005403 47.0
HFD1_k127_4943846_0 domain protein - - - 0.000000000000000000000000000000000000001789 166.0
HFD1_k127_5090829_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.311e-262 831.0
HFD1_k127_5090829_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 438.0
HFD1_k127_5090829_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 342.0
HFD1_k127_5090829_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000001099 185.0
HFD1_k127_5090829_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000002064 184.0
HFD1_k127_5090829_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000001022 181.0
HFD1_k127_5090829_6 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000002168 141.0
HFD1_k127_5090829_7 peptidyl-tyrosine sulfation - - - 0.0008954 52.0
HFD1_k127_5142262_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 473.0
HFD1_k127_5142262_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 459.0
HFD1_k127_5142262_10 - - - - 0.00000001468 60.0
HFD1_k127_5142262_11 - K07272,K20543,K21007 - - 0.00005384 51.0
HFD1_k127_5142262_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 461.0
HFD1_k127_5142262_3 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 436.0
HFD1_k127_5142262_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 331.0
HFD1_k127_5142262_5 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001982 278.0
HFD1_k127_5142262_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003434 255.0
HFD1_k127_5142262_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003664 252.0
HFD1_k127_5142262_8 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000005061 149.0
HFD1_k127_5142262_9 domain protein - - - 0.0000000000000000009039 101.0
HFD1_k127_5162839_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 387.0
HFD1_k127_5162839_1 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 306.0
HFD1_k127_5162839_2 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000007812 123.0
HFD1_k127_5183591_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.862e-294 910.0
HFD1_k127_5183591_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 8.06e-259 810.0
HFD1_k127_5183591_10 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 413.0
HFD1_k127_5183591_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 409.0
HFD1_k127_5183591_12 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 399.0
HFD1_k127_5183591_14 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 372.0
HFD1_k127_5183591_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 361.0
HFD1_k127_5183591_16 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 359.0
HFD1_k127_5183591_17 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 355.0
HFD1_k127_5183591_18 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 349.0
HFD1_k127_5183591_19 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 343.0
HFD1_k127_5183591_2 Squalene-hopene cyclase C-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 9.258e-240 759.0
HFD1_k127_5183591_20 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 332.0
HFD1_k127_5183591_21 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 317.0
HFD1_k127_5183591_22 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 307.0
HFD1_k127_5183591_23 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 284.0
HFD1_k127_5183591_24 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004638 273.0
HFD1_k127_5183591_25 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 270.0
HFD1_k127_5183591_26 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001567 278.0
HFD1_k127_5183591_27 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002458 258.0
HFD1_k127_5183591_28 Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003954 269.0
HFD1_k127_5183591_29 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005675 277.0
HFD1_k127_5183591_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.117e-199 651.0
HFD1_k127_5183591_30 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001209 244.0
HFD1_k127_5183591_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005785 233.0
HFD1_k127_5183591_32 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000004609 219.0
HFD1_k127_5183591_33 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000002378 220.0
HFD1_k127_5183591_34 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0000000000000000000000000000000000000000000000000000003464 202.0
HFD1_k127_5183591_35 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000002582 194.0
HFD1_k127_5183591_36 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000001083 192.0
HFD1_k127_5183591_37 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000002137 175.0
HFD1_k127_5183591_38 SPTR Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000002716 172.0
HFD1_k127_5183591_39 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000001591 164.0
HFD1_k127_5183591_4 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 574.0
HFD1_k127_5183591_40 GDSL-like Lipase/Acylhydrolase K12686 - - 0.0000000000000000000000000000000000000004239 167.0
HFD1_k127_5183591_41 MlaC protein K07323 - - 0.00000000000000000000000000000000001073 144.0
HFD1_k127_5183591_42 Cation efflux family - - - 0.00000000000000000000000000000000799 130.0
HFD1_k127_5183591_43 - - - - 0.0000000000000000000000000000000521 129.0
HFD1_k127_5183591_44 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000002417 134.0
HFD1_k127_5183591_45 Methyltransferase domain - - - 0.000000000000000000000000000005598 128.0
HFD1_k127_5183591_46 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000002444 116.0
HFD1_k127_5183591_47 PFAM RNA recognition motif - - - 0.0000000000000000000000001591 110.0
HFD1_k127_5183591_48 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000009624 109.0
HFD1_k127_5183591_49 Phosphorylase superfamily - - - 0.000000000000000000001696 104.0
HFD1_k127_5183591_5 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 470.0
HFD1_k127_5183591_50 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000001269 94.0
HFD1_k127_5183591_51 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000116 79.0
HFD1_k127_5183591_52 Cupin domain - - - 0.000000000000001328 78.0
HFD1_k127_5183591_53 Cation efflux family - - - 0.00000000000261 68.0
HFD1_k127_5183591_54 mercury ion transmembrane transporter activity - - - 0.0000000000107 66.0
HFD1_k127_5183591_55 PFAM UspA domain protein - - - 0.0000000006675 66.0
HFD1_k127_5183591_56 sulfur relay protein TusB DsrH K07237 - - 0.000000009354 59.0
HFD1_k127_5183591_57 response regulator, receiver - - - 0.000001973 53.0
HFD1_k127_5183591_58 DsrE/DsrF-like family K07235 - - 0.0001283 47.0
HFD1_k127_5183591_59 tRNA processing K07236 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.0001969 49.0
HFD1_k127_5183591_6 Pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 456.0
HFD1_k127_5183591_60 - - - - 0.0002629 52.0
HFD1_k127_5183591_7 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 442.0
HFD1_k127_5183591_8 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 424.0
HFD1_k127_5183591_9 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 425.0
HFD1_k127_5299400_0 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 602.0
HFD1_k127_5299400_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 544.0
HFD1_k127_5299400_10 Signal transduction histidine kinase, nitrogen specific K07708 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000006427 205.0
HFD1_k127_5299400_11 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000006958 154.0
HFD1_k127_5299400_12 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000004554 147.0
HFD1_k127_5299400_13 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000002878 94.0
HFD1_k127_5299400_14 pfkB family carbohydrate kinase - - - 0.0000000001673 63.0
HFD1_k127_5299400_16 - - - - 0.00002086 53.0
HFD1_k127_5299400_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 441.0
HFD1_k127_5299400_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 423.0
HFD1_k127_5299400_4 response regulator K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 406.0
HFD1_k127_5299400_5 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 381.0
HFD1_k127_5299400_6 PFAM Aminotransferase, class IV K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000009647 269.0
HFD1_k127_5299400_8 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000009479 228.0
HFD1_k127_5299400_9 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000006809 210.0
HFD1_k127_5310294_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.017e-313 979.0
HFD1_k127_5310294_1 COG0058 Glucan phosphorylase - - - 1.733e-255 799.0
HFD1_k127_5310294_10 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000001732 180.0
HFD1_k127_5310294_11 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000007945 167.0
HFD1_k127_5310294_12 translation release factor activity - - - 0.000000000000000000000000000000000000002466 150.0
HFD1_k127_5310294_13 RDD family - - - 0.0000000000000000000000001553 110.0
HFD1_k127_5310294_14 exodeoxyribonuclease I activity - - - 0.00000000001301 68.0
HFD1_k127_5310294_15 rod shape-determining protein MreD K03571 - - 0.00008545 51.0
HFD1_k127_5310294_2 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 527.0
HFD1_k127_5310294_3 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 497.0
HFD1_k127_5310294_4 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 437.0
HFD1_k127_5310294_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 421.0
HFD1_k127_5310294_6 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 411.0
HFD1_k127_5310294_7 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007169 286.0
HFD1_k127_5310294_8 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000001232 241.0
HFD1_k127_5310294_9 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000009738 207.0
HFD1_k127_5310936_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 520.0
HFD1_k127_5310936_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 406.0
HFD1_k127_5310936_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 319.0
HFD1_k127_5310936_3 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009615 250.0
HFD1_k127_5310936_4 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000001197 182.0
HFD1_k127_5310936_5 MgtC family K07507 - - 0.00000000000000000000000000000000002521 143.0
HFD1_k127_5310936_6 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000001994 130.0
HFD1_k127_5310936_7 sister chromatid segregation - - - 0.00000000008512 74.0
HFD1_k127_5310936_8 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000007581 59.0
HFD1_k127_5315020_0 Aconitase C-terminal domain K01681 - 4.2.1.3 6.374e-299 928.0
HFD1_k127_5315020_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 555.0
HFD1_k127_5315020_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 454.0
HFD1_k127_5315020_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 333.0
HFD1_k127_5315020_4 Aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 323.0
HFD1_k127_5315020_5 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000007849 221.0
HFD1_k127_5315020_6 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000001082 184.0
HFD1_k127_5315020_8 - - - - 0.0001919 44.0
HFD1_k127_5341953_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1376.0
HFD1_k127_5341953_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.136e-294 913.0
HFD1_k127_5341953_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 325.0
HFD1_k127_5341953_11 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 321.0
HFD1_k127_5341953_12 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 314.0
HFD1_k127_5341953_13 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 303.0
HFD1_k127_5341953_14 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003961 239.0
HFD1_k127_5341953_15 PFAM Glycosyl transferase family 2 K09931 - - 0.0000000000000000000000000000000000000000000000000000000006032 211.0
HFD1_k127_5341953_16 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.00000000000000000000000000000000000000003847 158.0
HFD1_k127_5341953_17 GGDEF domain - - - 0.00000000000000000000000000000000000000003882 169.0
HFD1_k127_5341953_18 Uncharacterized protein conserved in bacteria (DUF2064) K09931,K20742 - 3.4.14.13 0.0000000000000000000000000000000000000002981 157.0
HFD1_k127_5341953_19 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000000007234 102.0
HFD1_k127_5341953_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 8.502e-257 805.0
HFD1_k127_5341953_20 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000001264 88.0
HFD1_k127_5341953_21 Transcriptional regulator K03892,K21903 - - 0.000000000001867 73.0
HFD1_k127_5341953_22 Sporulation and spore germination - - - 0.00000000000396 74.0
HFD1_k127_5341953_24 Acetyltransferase, GNAT family K00657 - 2.3.1.57 0.000009817 54.0
HFD1_k127_5341953_3 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 568.0
HFD1_k127_5341953_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 515.0
HFD1_k127_5341953_5 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 410.0
HFD1_k127_5341953_6 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 370.0
HFD1_k127_5341953_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 358.0
HFD1_k127_5341953_8 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 360.0
HFD1_k127_5341953_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 355.0
HFD1_k127_5384762_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1556.0
HFD1_k127_5384762_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 558.0
HFD1_k127_5384762_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 497.0
HFD1_k127_5384762_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 393.0
HFD1_k127_5384762_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000004827 233.0
HFD1_k127_5384762_5 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000043 196.0
HFD1_k127_5384762_6 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000002531 157.0
HFD1_k127_5384762_7 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000003898 140.0
HFD1_k127_5384762_8 Transposase K07491 - - 0.000000000000000000000000003827 114.0
HFD1_k127_5455402_0 cell redox homeostasis - - - 2.766e-204 647.0
HFD1_k127_5455402_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 588.0
HFD1_k127_5455402_10 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000001803 160.0
HFD1_k127_5455402_11 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000009061 145.0
HFD1_k127_5455402_12 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000228 138.0
HFD1_k127_5455402_13 iron-sulfur cluster assembly - - - 0.000000000000000000000002938 104.0
HFD1_k127_5455402_14 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.00000000000000000000002276 100.0
HFD1_k127_5455402_15 Cobalt transport protein K16785 - - 0.000000000001244 76.0
HFD1_k127_5455402_17 Transposase IS200 like K07491 - - 0.0000000007545 60.0
HFD1_k127_5455402_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 460.0
HFD1_k127_5455402_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 436.0
HFD1_k127_5455402_4 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 348.0
HFD1_k127_5455402_5 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 316.0
HFD1_k127_5455402_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000003233 259.0
HFD1_k127_5455402_7 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000005949 238.0
HFD1_k127_5455402_8 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000002266 242.0
HFD1_k127_5455402_9 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000004509 212.0
HFD1_k127_5487065_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 454.0
HFD1_k127_5487065_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 404.0
HFD1_k127_5487065_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000000000000000000001274 124.0
HFD1_k127_5487065_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000006894 117.0
HFD1_k127_5555618_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2067.0
HFD1_k127_5555618_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1873.0
HFD1_k127_5555618_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 336.0
HFD1_k127_5555618_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002584 253.0
HFD1_k127_5555618_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000158 205.0
HFD1_k127_5555618_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000002508 195.0
HFD1_k127_5555618_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000007005 148.0
HFD1_k127_5555618_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000002461 81.0
HFD1_k127_5555618_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000129 73.0
HFD1_k127_5555618_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000004363 70.0
HFD1_k127_5584637_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 9.543e-304 955.0
HFD1_k127_5584637_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.677e-206 649.0
HFD1_k127_5584637_10 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000001427 229.0
HFD1_k127_5584637_11 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000001632 192.0
HFD1_k127_5584637_12 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit K01546 - 3.6.3.12 0.0000000000000000000000000000000000000000001011 162.0
HFD1_k127_5584637_13 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000008076 77.0
HFD1_k127_5584637_14 - - - - 0.000000003467 63.0
HFD1_k127_5584637_15 - - - - 0.00009331 47.0
HFD1_k127_5584637_16 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 0.000392 44.0
HFD1_k127_5584637_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 421.0
HFD1_k127_5584637_3 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 398.0
HFD1_k127_5584637_4 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 366.0
HFD1_k127_5584637_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 361.0
HFD1_k127_5584637_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 321.0
HFD1_k127_5584637_7 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 312.0
HFD1_k127_5584637_8 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004584 267.0
HFD1_k127_5584637_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000721 234.0
HFD1_k127_5640969_0 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 470.0
HFD1_k127_5640969_1 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000002053 175.0
HFD1_k127_5640969_2 Membrane - - - 0.000000000000000000000000000000000000000000008376 168.0
HFD1_k127_5640969_3 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000001547 70.0
HFD1_k127_5640969_4 Membrane - - - 0.000000000003364 66.0
HFD1_k127_5640969_5 AAA ATPase, central domain protein - - - 0.000000000004231 69.0
HFD1_k127_5644049_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 624.0
HFD1_k127_5644049_1 eight transmembrane protein EpsH - - - 0.0000000000000000000000000000000000000000001339 170.0
HFD1_k127_5644049_2 Histidine kinase - - - 0.000000000000000000000007615 108.0
HFD1_k127_5644049_3 Protein of unknown function (DUF3485) - - - 0.000000000000000003774 93.0
HFD1_k127_5644049_4 Glycosyltransferase like family 2 - - - 0.000000002049 64.0
HFD1_k127_5678201_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 2.071e-215 691.0
HFD1_k127_5678201_1 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 572.0
HFD1_k127_5678201_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000004466 158.0
HFD1_k127_5678201_11 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000002981 153.0
HFD1_k127_5678201_12 Protein of unknown function (DUF1349) - - - 0.000000000000000000000000000005003 124.0
HFD1_k127_5678201_13 protein-disulfide reductase activity - - - 0.0000000000000000000000000732 114.0
HFD1_k127_5678201_14 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000009612 110.0
HFD1_k127_5678201_15 Belongs to the 'phage' integrase family - - - 0.00000000001016 68.0
HFD1_k127_5678201_16 General secretion pathway protein K02457 - - 0.000000000125 68.0
HFD1_k127_5678201_17 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000595 68.0
HFD1_k127_5678201_18 fimbrial assembly K02461 - - 0.0000000009562 71.0
HFD1_k127_5678201_19 pilus assembly protein PilW K02459,K02672 - - 0.000000003531 67.0
HFD1_k127_5678201_2 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 389.0
HFD1_k127_5678201_20 - - - - 0.000000005053 57.0
HFD1_k127_5678201_21 fimbrial assembly K02461 - - 0.00000001556 67.0
HFD1_k127_5678201_22 type IV pilus modification protein PilV K02458 - - 0.00000002956 61.0
HFD1_k127_5678201_23 Type II secretion system (T2SS), protein M subtype b - - - 0.0000001956 59.0
HFD1_k127_5678201_3 Glycosyl transferase, family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 336.0
HFD1_k127_5678201_4 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 325.0
HFD1_k127_5678201_5 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
HFD1_k127_5678201_6 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001349 214.0
HFD1_k127_5678201_7 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000005587 173.0
HFD1_k127_5678201_8 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000479 179.0
HFD1_k127_5678201_9 Galactose-3-O-sulfotransferase - - - 0.0000000000000000000000000000000000000001437 160.0
HFD1_k127_5705772_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009345 286.0
HFD1_k127_5705772_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000003554 146.0
HFD1_k127_5705772_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000004087 146.0
HFD1_k127_5705772_3 Universal stress protein - - - 0.000000000000001695 87.0
HFD1_k127_5728092_0 PFAM FAD linked oxidase domain protein - - - 1.914e-259 805.0
HFD1_k127_5728092_1 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 3.107e-200 634.0
HFD1_k127_5728092_2 Predicted membrane protein (DUF2127) - - - 0.0000000000000000000000000000000000000000000000000005191 188.0
HFD1_k127_5728092_3 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.0000000000000000000000000004437 115.0
HFD1_k127_5732139_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1335.0
HFD1_k127_5732139_1 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1069.0
HFD1_k127_5732139_10 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 344.0
HFD1_k127_5732139_11 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 323.0
HFD1_k127_5732139_12 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 306.0
HFD1_k127_5732139_13 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 298.0
HFD1_k127_5732139_14 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 284.0
HFD1_k127_5732139_15 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004678 279.0
HFD1_k127_5732139_16 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001638 272.0
HFD1_k127_5732139_17 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003702 250.0
HFD1_k127_5732139_18 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000002316 254.0
HFD1_k127_5732139_19 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000002207 228.0
HFD1_k127_5732139_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.031e-209 661.0
HFD1_k127_5732139_20 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000003367 210.0
HFD1_k127_5732139_21 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000002789 182.0
HFD1_k127_5732139_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000000004625 186.0
HFD1_k127_5732139_23 TraB family K09973 - - 0.00000000000000000000000000000000000000000000002695 183.0
HFD1_k127_5732139_24 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.00000000000000000000000000000000000000000000003574 180.0
HFD1_k127_5732139_25 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000003761 159.0
HFD1_k127_5732139_26 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000006992 151.0
HFD1_k127_5732139_27 radical SAM K06871 - - 0.00000000000000000000000000000000000001363 156.0
HFD1_k127_5732139_28 PFAM PHP domain - - - 0.00000000000000000000000000000000000002 151.0
HFD1_k127_5732139_29 AMP binding K09118,K13693 - 2.4.1.266 0.000000000000000000000000002001 122.0
HFD1_k127_5732139_3 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 611.0
HFD1_k127_5732139_30 MacB-like periplasmic core domain K02004 - - 0.000000000000002068 82.0
HFD1_k127_5732139_4 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 505.0
HFD1_k127_5732139_5 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 468.0
HFD1_k127_5732139_6 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 458.0
HFD1_k127_5732139_7 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 447.0
HFD1_k127_5732139_8 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 359.0
HFD1_k127_5732139_9 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 350.0
HFD1_k127_5732267_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 578.0
HFD1_k127_5732267_1 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 561.0
HFD1_k127_5732267_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000001262 109.0
HFD1_k127_5732267_11 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000000000001477 101.0
HFD1_k127_5732267_12 - - - - 0.00000003367 59.0
HFD1_k127_5732267_13 histidine kinase HAMP region domain protein K03406 - - 0.0000003636 59.0
HFD1_k127_5732267_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.000000499 52.0
HFD1_k127_5732267_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 502.0
HFD1_k127_5732267_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 399.0
HFD1_k127_5732267_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 355.0
HFD1_k127_5732267_5 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007329 307.0
HFD1_k127_5732267_6 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 291.0
HFD1_k127_5732267_7 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000004884 229.0
HFD1_k127_5732267_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000008641 123.0
HFD1_k127_5750477_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1487.0
HFD1_k127_5750477_1 Aminotransferase class I and II K14261 - - 1.759e-207 652.0
HFD1_k127_5750477_10 Protein of unknown function (DUF3443) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 402.0
HFD1_k127_5750477_11 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 379.0
HFD1_k127_5750477_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 375.0
HFD1_k127_5750477_13 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 351.0
HFD1_k127_5750477_14 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 339.0
HFD1_k127_5750477_15 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 340.0
HFD1_k127_5750477_16 4Fe-4S binding domain K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 338.0
HFD1_k127_5750477_17 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 335.0
HFD1_k127_5750477_18 4Fe-4S binding domain K02573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 323.0
HFD1_k127_5750477_19 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 289.0
HFD1_k127_5750477_2 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 572.0
HFD1_k127_5750477_20 K06861 lipopolysaccharide export system ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 289.0
HFD1_k127_5750477_21 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004902 265.0
HFD1_k127_5750477_22 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000006665 257.0
HFD1_k127_5750477_23 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000001269 241.0
HFD1_k127_5750477_24 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
HFD1_k127_5750477_25 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000007904 227.0
HFD1_k127_5750477_26 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000001797 214.0
HFD1_k127_5750477_27 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000005555 197.0
HFD1_k127_5750477_28 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000001134 182.0
HFD1_k127_5750477_29 Protein of unknown function (DUF2844) - - - 0.0000000000000000000000000000000000000000000001107 172.0
HFD1_k127_5750477_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 578.0
HFD1_k127_5750477_30 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000000001859 167.0
HFD1_k127_5750477_31 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000000000002489 162.0
HFD1_k127_5750477_32 OstA-like protein K09774 - - 0.00000000000000000000000000000000000001271 149.0
HFD1_k127_5750477_33 Nitroreductase family - - - 0.00000000000000000000000000000000005069 141.0
HFD1_k127_5750477_34 - - - - 0.0000000000000000000000000000000003873 134.0
HFD1_k127_5750477_35 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000004374 125.0
HFD1_k127_5750477_36 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000001675 115.0
HFD1_k127_5750477_37 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.00000000000000000000000002271 111.0
HFD1_k127_5750477_38 negative regulation of establishment of protein localization K02570 GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032879,GO:0032880,GO:0033218,GO:0042277,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0065007,GO:0070201,GO:0090087,GO:1904950 - 0.00000000000000000000000159 106.0
HFD1_k127_5750477_39 - - - - 0.000000000000000000002599 101.0
HFD1_k127_5750477_4 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 545.0
HFD1_k127_5750477_40 - - - - 0.00000000000000001793 89.0
HFD1_k127_5750477_41 Kinase domain K12132 - 2.7.11.1 0.00000000000002137 82.0
HFD1_k127_5750477_42 - - - - 0.0000000000002258 71.0
HFD1_k127_5750477_43 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000004198 72.0
HFD1_k127_5750477_44 dienelactone hydrolase - - - 0.0000000001133 68.0
HFD1_k127_5750477_45 transferase activity, transferring glycosyl groups - - - 0.000000007146 64.0
HFD1_k127_5750477_46 Lipopolysaccharide-assembly, LptC-related - - - 0.000008192 54.0
HFD1_k127_5750477_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 539.0
HFD1_k127_5750477_6 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 531.0
HFD1_k127_5750477_7 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 514.0
HFD1_k127_5750477_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 455.0
HFD1_k127_5750477_9 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 439.0
HFD1_k127_5792658_0 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 343.0
HFD1_k127_5792658_1 haemagglutination activity domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 362.0
HFD1_k127_5792658_2 hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006489 250.0
HFD1_k127_5792658_3 Universal stress protein family - - - 0.00000000000000000000000008114 111.0
HFD1_k127_5792658_4 AMP binding K03322,K09944 - - 0.0000000000004387 71.0
HFD1_k127_5792658_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000002359 59.0
HFD1_k127_5792658_6 PIN domain K07065 - - 0.0005 48.0
HFD1_k127_5852761_0 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 461.0
HFD1_k127_5852761_1 Homeodomain-like domain - - - 0.00000000000000000000000000000000000000000001489 176.0
HFD1_k127_5852761_2 - - - - 0.0000000000000000001121 94.0
HFD1_k127_5852761_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000008303 93.0
HFD1_k127_5921508_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.831e-289 899.0
HFD1_k127_5921508_1 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 344.0
HFD1_k127_5921508_2 Type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006107 291.0
HFD1_k127_5921508_3 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000001917 252.0
HFD1_k127_5921508_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000006937 241.0
HFD1_k127_5921508_5 pathogenesis K13669 - - 0.00000000000000000000000000000000000000000000000000000004359 217.0
HFD1_k127_5921508_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000007513 113.0
HFD1_k127_5921508_7 PFAM Fimbrial assembly K02663 - - 0.000000000001459 74.0
HFD1_k127_5921508_8 Pilus assembly protein, PilP K02665 - - 0.00000000001069 72.0
HFD1_k127_5921508_9 Pilus assembly protein, PilO K02664 - - 0.00000000006235 70.0
HFD1_k127_5943270_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1752.0
HFD1_k127_5943270_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.9e-215 675.0
HFD1_k127_5943270_10 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 359.0
HFD1_k127_5943270_11 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 350.0
HFD1_k127_5943270_12 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 353.0
HFD1_k127_5943270_13 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 349.0
HFD1_k127_5943270_14 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 349.0
HFD1_k127_5943270_15 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 331.0
HFD1_k127_5943270_16 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 327.0
HFD1_k127_5943270_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 328.0
HFD1_k127_5943270_18 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 323.0
HFD1_k127_5943270_19 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 306.0
HFD1_k127_5943270_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 612.0
HFD1_k127_5943270_20 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
HFD1_k127_5943270_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000206 279.0
HFD1_k127_5943270_22 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000048 281.0
HFD1_k127_5943270_23 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000148 256.0
HFD1_k127_5943270_24 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000009605 246.0
HFD1_k127_5943270_25 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000001265 241.0
HFD1_k127_5943270_26 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001842 231.0
HFD1_k127_5943270_27 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002242 239.0
HFD1_k127_5943270_28 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000003428 233.0
HFD1_k127_5943270_29 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000002132 218.0
HFD1_k127_5943270_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 556.0
HFD1_k127_5943270_30 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000004561 209.0
HFD1_k127_5943270_31 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001074 205.0
HFD1_k127_5943270_32 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.00000000000000000000000000000000000000000000000000000001987 200.0
HFD1_k127_5943270_33 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000007255 198.0
HFD1_k127_5943270_35 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002636 192.0
HFD1_k127_5943270_36 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000002732 197.0
HFD1_k127_5943270_37 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000000000000000000000000000000007948 193.0
HFD1_k127_5943270_38 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000005575 192.0
HFD1_k127_5943270_39 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000004788 184.0
HFD1_k127_5943270_4 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 557.0
HFD1_k127_5943270_40 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000001031 181.0
HFD1_k127_5943270_41 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000001446 181.0
HFD1_k127_5943270_42 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002091 175.0
HFD1_k127_5943270_43 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000000000000000000000005396 173.0
HFD1_k127_5943270_44 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000001483 172.0
HFD1_k127_5943270_45 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001698 166.0
HFD1_k127_5943270_46 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000003066 169.0
HFD1_k127_5943270_47 Yhs domain-containing protein - - - 0.00000000000000000000000000000000000000000004983 166.0
HFD1_k127_5943270_48 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000261 167.0
HFD1_k127_5943270_49 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000001314 154.0
HFD1_k127_5943270_5 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 517.0
HFD1_k127_5943270_50 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000005408 163.0
HFD1_k127_5943270_51 - K07112 - - 0.0000000000000000000000000000000000000001905 155.0
HFD1_k127_5943270_52 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000001758 155.0
HFD1_k127_5943270_53 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000002762 152.0
HFD1_k127_5943270_54 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000003276 148.0
HFD1_k127_5943270_55 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000003884 143.0
HFD1_k127_5943270_56 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000000007883 143.0
HFD1_k127_5943270_57 Thioredoxin-like - - - 0.00000000000000000000000000000000002346 141.0
HFD1_k127_5943270_58 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000003861 136.0
HFD1_k127_5943270_59 4Fe-4S binding domain - - - 0.00000000000000000000000000000000005726 145.0
HFD1_k127_5943270_6 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 490.0
HFD1_k127_5943270_60 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000002521 132.0
HFD1_k127_5943270_61 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000007351 135.0
HFD1_k127_5943270_62 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000064 115.0
HFD1_k127_5943270_63 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000009532 105.0
HFD1_k127_5943270_64 Domain of unknown function (DUF4203) - - - 0.00000000000000000000001127 106.0
HFD1_k127_5943270_65 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000003218 94.0
HFD1_k127_5943270_66 - - - - 0.000000000000000007384 90.0
HFD1_k127_5943270_67 Domain of unknown function (DUF4382) - - - 0.0000000000000001314 90.0
HFD1_k127_5943270_68 Ribosomal protein L36 K02919 - - 0.000000000000001058 77.0
HFD1_k127_5943270_69 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000007538 76.0
HFD1_k127_5943270_7 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 407.0
HFD1_k127_5943270_70 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000004918 65.0
HFD1_k127_5943270_71 - - - - 0.000000000433 63.0
HFD1_k127_5943270_72 TonB family K03646,K03832 - - 0.0000000007885 68.0
HFD1_k127_5943270_8 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 365.0
HFD1_k127_5943270_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 362.0
HFD1_k127_5947903_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1125.0
HFD1_k127_5947903_1 DNA polymerase K02347 - - 7.142e-208 661.0
HFD1_k127_5947903_10 TIGRFAM phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000365 219.0
HFD1_k127_5947903_11 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000007242 214.0
HFD1_k127_5947903_12 Adenylate kinase - - - 0.0000000000000000000000000000000000000000000000000007354 190.0
HFD1_k127_5947903_13 GAF domain - - - 0.0000000000000000000000000000000000000000000000002923 190.0
HFD1_k127_5947903_14 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000002447 172.0
HFD1_k127_5947903_15 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000001179 155.0
HFD1_k127_5947903_17 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000002438 74.0
HFD1_k127_5947903_18 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000006199 79.0
HFD1_k127_5947903_19 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000001248 69.0
HFD1_k127_5947903_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 5.153e-203 668.0
HFD1_k127_5947903_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 586.0
HFD1_k127_5947903_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 557.0
HFD1_k127_5947903_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 539.0
HFD1_k127_5947903_6 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 479.0
HFD1_k127_5947903_7 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 365.0
HFD1_k127_5947903_8 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 357.0
HFD1_k127_5947903_9 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002063 269.0
HFD1_k127_5972646_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 383.0
HFD1_k127_5972646_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 284.0
HFD1_k127_5972646_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000004985 234.0
HFD1_k127_5972646_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000002094 167.0
HFD1_k127_5972646_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000006982 155.0
HFD1_k127_5972646_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003144 102.0
HFD1_k127_5972646_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000266 84.0
HFD1_k127_5973719_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.664e-309 956.0
HFD1_k127_5973719_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.544e-240 753.0
HFD1_k127_5973719_10 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000007165 254.0
HFD1_k127_5973719_11 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000003142 247.0
HFD1_k127_5973719_12 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005422 240.0
HFD1_k127_5973719_13 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000259 241.0
HFD1_k127_5973719_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000009423 218.0
HFD1_k127_5973719_15 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000003256 215.0
HFD1_k127_5973719_16 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00177,K00187 - 1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000002569 186.0
HFD1_k127_5973719_17 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000007227 172.0
HFD1_k127_5973719_18 Universal stress protein family - - - 0.0000000000000000000000000000000000000002953 155.0
HFD1_k127_5973719_19 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.00000000000000000000000000000000000002964 154.0
HFD1_k127_5973719_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 611.0
HFD1_k127_5973719_20 proteolysis K03665 - - 0.0000000000000000000000000003843 121.0
HFD1_k127_5973719_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 489.0
HFD1_k127_5973719_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 470.0
HFD1_k127_5973719_5 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 434.0
HFD1_k127_5973719_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 441.0
HFD1_k127_5973719_7 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 377.0
HFD1_k127_5973719_8 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 368.0
HFD1_k127_5973719_9 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 338.0
HFD1_k127_6106223_0 Pfam:KaiC K08482 - - 3.527e-230 727.0
HFD1_k127_6106223_1 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001878 271.0
HFD1_k127_6106223_2 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000002676 169.0
HFD1_k127_6106223_3 KaiB K08481 - - 0.000000000000000000000000000000000000000004098 158.0
HFD1_k127_6106223_4 KaiB K08481 - - 0.00000000000000000000000000000000000001194 147.0
HFD1_k127_6106223_5 response regulator K02485 - - 0.000000000000000000000001056 108.0
HFD1_k127_6106223_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000008812 69.0
HFD1_k127_6197585_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 532.0
HFD1_k127_6197585_1 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 516.0
HFD1_k127_6197585_2 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007908 254.0
HFD1_k127_6197585_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 258.0
HFD1_k127_6197585_4 Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000001113 171.0
HFD1_k127_6197585_5 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000002284 164.0
HFD1_k127_6197585_7 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000003014 99.0
HFD1_k127_6197585_8 Transcription factor zinc-finger - - - 0.00000000000000000001034 99.0
HFD1_k127_6197585_9 Heavy-metal-associated domain K07213 - - 0.000000653 53.0
HFD1_k127_6215704_0 TIGRFAM Ammonium transporter K03320 - - 2.786e-258 805.0
HFD1_k127_6215704_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000001145 183.0
HFD1_k127_6215704_2 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000001259 173.0
HFD1_k127_6215704_3 Protein of unknown function (DUF1646) - - - 0.000000000000000000000000000000000000000001706 164.0
HFD1_k127_6252267_0 NAD+ diphosphatase activity K03426,K20449 - 1.3.7.1,3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 299.0
HFD1_k127_6252267_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000001137 230.0
HFD1_k127_6252267_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000117 212.0
HFD1_k127_6252267_3 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001883 208.0
HFD1_k127_6252267_4 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000004637 162.0
HFD1_k127_6252267_5 PFAM FeoA family protein K04758 - - 0.0000000000000001013 83.0
HFD1_k127_6252267_6 Phage integrase family K14059 - - 0.000000000000001328 78.0
HFD1_k127_6252267_7 Universal stress protein family - - - 0.000000003494 63.0
HFD1_k127_6252267_8 Acetyltransferase K00661 - 2.3.1.79 0.000006504 51.0
HFD1_k127_6252267_9 Protein of unknown function (DUF2934) - - - 0.00000948 50.0
HFD1_k127_6414807_0 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 545.0
HFD1_k127_6414807_1 PFAM Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 541.0
HFD1_k127_6414807_10 - - - - 0.00000000000000000000000002192 109.0
HFD1_k127_6414807_11 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00004083 55.0
HFD1_k127_6414807_2 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 529.0
HFD1_k127_6414807_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 523.0
HFD1_k127_6414807_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 316.0
HFD1_k127_6414807_5 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000000000000002987 220.0
HFD1_k127_6414807_6 YbbR-like protein - - - 0.00000000000000000000000000000000000000000001075 169.0
HFD1_k127_6414807_7 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.000000000000000000000000000000000000000225 160.0
HFD1_k127_6414807_8 - - - - 0.000000000000000000000000000002805 122.0
HFD1_k127_6414807_9 domain protein K02238 - - 0.00000000000000000000000000283 125.0
HFD1_k127_6422899_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1079.0
HFD1_k127_6422899_1 TIGRFAM alpha-glucan - - - 6.609e-199 625.0
HFD1_k127_6422899_10 Protein of unknown function (DUF3568) - - - 0.0000001042 59.0
HFD1_k127_6422899_11 phosphonoacetaldehyde hydrolase activity K00817,K07025,K20866 - 2.6.1.9,3.1.3.10 0.00004913 47.0
HFD1_k127_6422899_2 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 421.0
HFD1_k127_6422899_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004931 245.0
HFD1_k127_6422899_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000002002 160.0
HFD1_k127_6422899_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000002812 142.0
HFD1_k127_6422899_6 - - - - 0.00000000000000000000000000344 117.0
HFD1_k127_6422899_7 antisigma factor binding K03598 - - 0.000000000001041 77.0
HFD1_k127_6422899_8 Belongs to the 'phage' integrase family - - - 0.000000000005866 69.0
HFD1_k127_6422899_9 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000008004 63.0
HFD1_k127_6534611_0 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 325.0
HFD1_k127_6534611_1 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000005243 171.0
HFD1_k127_6534611_2 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001436 106.0
HFD1_k127_6534611_3 Protein of unknown function DUF89 K09116 - - 0.000000000000000000001167 96.0
HFD1_k127_6545154_0 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 378.0
HFD1_k127_6545154_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 308.0
HFD1_k127_6545154_3 Histone deacetylase domain - - - 0.00000000000000002497 86.0
HFD1_k127_6545154_4 - - - - 0.00000000000132 76.0
HFD1_k127_6558325_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.774e-255 805.0
HFD1_k127_6558325_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.64e-225 712.0
HFD1_k127_6558325_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 443.0
HFD1_k127_6558325_11 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 430.0
HFD1_k127_6558325_12 C oxidoreductase subunit A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 411.0
HFD1_k127_6558325_13 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 405.0
HFD1_k127_6558325_14 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 378.0
HFD1_k127_6558325_15 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 372.0
HFD1_k127_6558325_16 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 321.0
HFD1_k127_6558325_17 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 322.0
HFD1_k127_6558325_18 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 310.0
HFD1_k127_6558325_19 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 310.0
HFD1_k127_6558325_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.801e-219 691.0
HFD1_k127_6558325_20 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 302.0
HFD1_k127_6558325_21 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002797 282.0
HFD1_k127_6558325_22 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003087 275.0
HFD1_k127_6558325_23 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002731 273.0
HFD1_k127_6558325_24 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000002371 255.0
HFD1_k127_6558325_25 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000001307 248.0
HFD1_k127_6558325_26 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000001381 227.0
HFD1_k127_6558325_27 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000006079 229.0
HFD1_k127_6558325_28 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000001042 214.0
HFD1_k127_6558325_29 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000001068 212.0
HFD1_k127_6558325_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.045e-206 651.0
HFD1_k127_6558325_30 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000001741 204.0
HFD1_k127_6558325_31 helix_turn_helix, cAMP Regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000002361 204.0
HFD1_k127_6558325_32 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000006276 194.0
HFD1_k127_6558325_33 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000004379 188.0
HFD1_k127_6558325_34 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000001533 175.0
HFD1_k127_6558325_35 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000003473 176.0
HFD1_k127_6558325_36 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000001402 177.0
HFD1_k127_6558325_37 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000003309 173.0
HFD1_k127_6558325_38 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000004783 162.0
HFD1_k127_6558325_39 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000007051 158.0
HFD1_k127_6558325_4 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 608.0
HFD1_k127_6558325_40 Uncharacterized ACR, COG1678 - - - 0.00000000000000000000000000000000000002501 153.0
HFD1_k127_6558325_41 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000000000775 138.0
HFD1_k127_6558325_42 nucleotide metabolic process - - - 0.000000000000000000000000000000003855 138.0
HFD1_k127_6558325_43 PFAM CBS domain - - - 0.0000000000000000000000000000003081 130.0
HFD1_k127_6558325_44 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000116 122.0
HFD1_k127_6558325_45 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000000002271 111.0
HFD1_k127_6558325_46 nucleotidyltransferase activity K07075 - - 0.000000000000000000000003564 109.0
HFD1_k127_6558325_47 Putative regulatory protein - - - 0.000000000000000000000003928 104.0
HFD1_k127_6558325_48 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000004912 104.0
HFD1_k127_6558325_49 - - - - 0.000000000000000000001243 100.0
HFD1_k127_6558325_5 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 560.0
HFD1_k127_6558325_50 Tetratricopeptide repeat - - - 0.0000000000000000001192 101.0
HFD1_k127_6558325_51 Domain of unknown function (DUF1858) - - - 0.0000000000000000002533 89.0
HFD1_k127_6558325_52 Roadblock/LC7 domain - - - 0.000000000000000008997 87.0
HFD1_k127_6558325_53 c oxidoreductase (Subunit b) - - - 0.00000000000000003043 85.0
HFD1_k127_6558325_54 - - - - 0.0000000000001385 81.0
HFD1_k127_6558325_55 4Fe-4S binding domain - - - 0.0000000000007676 70.0
HFD1_k127_6558325_56 - - - - 0.0000003589 57.0
HFD1_k127_6558325_58 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00001771 48.0
HFD1_k127_6558325_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 527.0
HFD1_k127_6558325_7 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 503.0
HFD1_k127_6558325_8 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 512.0
HFD1_k127_6558325_9 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 491.0
HFD1_k127_6587271_0 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 551.0
HFD1_k127_6587271_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 528.0
HFD1_k127_6587271_2 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.00000000000000000000000001242 111.0
HFD1_k127_6587271_3 HEAT-like repeat - - - 0.00000000000000000000001632 105.0
HFD1_k127_6607328_0 Protein conserved in bacteria - - - 7.03e-229 736.0
HFD1_k127_6607328_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.394e-226 730.0
HFD1_k127_6607328_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 359.0
HFD1_k127_6607328_11 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 342.0
HFD1_k127_6607328_12 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 336.0
HFD1_k127_6607328_13 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
HFD1_k127_6607328_14 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 290.0
HFD1_k127_6607328_15 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001983 254.0
HFD1_k127_6607328_16 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000002632 243.0
HFD1_k127_6607328_17 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000568 228.0
HFD1_k127_6607328_18 lactate metabolic process K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000000000001376 234.0
HFD1_k127_6607328_19 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000003075 226.0
HFD1_k127_6607328_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 595.0
HFD1_k127_6607328_20 Kelch motif - - - 0.00000000000000000000000000000000000000000000000000000000001618 229.0
HFD1_k127_6607328_21 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000000000006903 187.0
HFD1_k127_6607328_22 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000001346 179.0
HFD1_k127_6607328_23 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000002188 166.0
HFD1_k127_6607328_24 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000001698 134.0
HFD1_k127_6607328_25 - - - - 0.000000000000000000000000000002125 128.0
HFD1_k127_6607328_26 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000002593 125.0
HFD1_k127_6607328_27 - - - - 0.0000000000000000000000000005855 120.0
HFD1_k127_6607328_28 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000004341 95.0
HFD1_k127_6607328_29 Cysteine-rich small domain K07162 - - 0.00000000000000000163 88.0
HFD1_k127_6607328_3 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 509.0
HFD1_k127_6607328_30 Dystroglycan-type cadherin-like domains. - - - 0.00000000000002389 84.0
HFD1_k127_6607328_31 - - - - 0.000000000006072 68.0
HFD1_k127_6607328_32 Domain of unknown function (DUF4912) K09942 - - 0.000000001216 69.0
HFD1_k127_6607328_33 Bacterial regulatory proteins, luxR family K07684 - - 0.00000005116 59.0
HFD1_k127_6607328_4 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 494.0
HFD1_k127_6607328_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 446.0
HFD1_k127_6607328_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 416.0
HFD1_k127_6607328_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 373.0
HFD1_k127_6607328_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 368.0
HFD1_k127_6607328_9 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 361.0
HFD1_k127_6609535_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004874 277.0
HFD1_k127_6609535_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000142 86.0
HFD1_k127_6609535_2 Rubrerythrin - - - 0.000000000001898 68.0
HFD1_k127_6609535_3 Universal stress protein family - - - 0.00000000009389 66.0
HFD1_k127_6609535_4 Rubrerythrin - - - 0.0000000004921 60.0
HFD1_k127_6609535_5 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.000000001158 59.0
HFD1_k127_6618893_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 591.0
HFD1_k127_6618893_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 504.0
HFD1_k127_6618893_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 435.0
HFD1_k127_6618893_3 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 427.0
HFD1_k127_6618893_4 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009664 239.0
HFD1_k127_6618893_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000167 207.0
HFD1_k127_6633109_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 7.105e-297 919.0
HFD1_k127_6633109_1 Belongs to the ClpA ClpB family K03694 - - 1.409e-278 874.0
HFD1_k127_6633109_10 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 321.0
HFD1_k127_6633109_11 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 312.0
HFD1_k127_6633109_12 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 297.0
HFD1_k127_6633109_13 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003481 276.0
HFD1_k127_6633109_14 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003476 272.0
HFD1_k127_6633109_15 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002242 264.0
HFD1_k127_6633109_17 - - - - 0.0000000000000000000000000000000000000000000005397 170.0
HFD1_k127_6633109_18 Universal stress protein family - - - 0.0000000000000000000000000000000000000000004637 162.0
HFD1_k127_6633109_19 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000883 160.0
HFD1_k127_6633109_2 ABC transporter K06158 - - 1.251e-236 747.0
HFD1_k127_6633109_20 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000197 153.0
HFD1_k127_6633109_21 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000001587 158.0
HFD1_k127_6633109_22 Universal stress protein family - - - 0.0000000000000000000000000000000000001581 146.0
HFD1_k127_6633109_23 - - - - 0.0000000000000000000000000000000000002257 148.0
HFD1_k127_6633109_24 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000001794 123.0
HFD1_k127_6633109_25 ankyrin repeat - - - 0.0000000000000000005825 93.0
HFD1_k127_6633109_26 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000002503 78.0
HFD1_k127_6633109_27 PFAM thiamineS protein - - - 0.00000000001004 67.0
HFD1_k127_6633109_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 575.0
HFD1_k127_6633109_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 581.0
HFD1_k127_6633109_5 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 510.0
HFD1_k127_6633109_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 401.0
HFD1_k127_6633109_7 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 372.0
HFD1_k127_6633109_8 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 365.0
HFD1_k127_6633109_9 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 363.0
HFD1_k127_6648561_0 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 394.0
HFD1_k127_6648561_1 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 342.0
HFD1_k127_6648561_2 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000002178 203.0
HFD1_k127_6672039_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1162.0
HFD1_k127_6672039_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.206e-299 926.0
HFD1_k127_6672039_10 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000000004446 189.0
HFD1_k127_6672039_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000007266 132.0
HFD1_k127_6672039_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000005611 111.0
HFD1_k127_6672039_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000001278 78.0
HFD1_k127_6672039_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 4.751e-228 722.0
HFD1_k127_6672039_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.933e-211 662.0
HFD1_k127_6672039_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 575.0
HFD1_k127_6672039_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 492.0
HFD1_k127_6672039_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 466.0
HFD1_k127_6672039_7 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 338.0
HFD1_k127_6672039_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 310.0
HFD1_k127_6672039_9 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000002625 208.0
HFD1_k127_6710646_0 - - - - 0.000000000000000000000000000000000000000000000000000000007937 209.0
HFD1_k127_6710646_1 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000001533 196.0
HFD1_k127_6710646_2 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000009994 144.0
HFD1_k127_6710646_3 PFAM pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000002339 141.0
HFD1_k127_6710646_4 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000001148 92.0
HFD1_k127_6761945_0 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 339.0
HFD1_k127_6761945_1 SAF K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000007875 237.0
HFD1_k127_6761945_2 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000001333 185.0
HFD1_k127_6761945_3 protocatechuate 3,4-dioxygenase - - - 0.000000000000000000000000000000000000000000000003328 178.0
HFD1_k127_6776261_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 555.0
HFD1_k127_6776261_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 410.0
HFD1_k127_6776261_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 391.0
HFD1_k127_6776261_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 355.0
HFD1_k127_6776261_4 GYD domain - - - 0.00000000000000000000000000000000001939 137.0
HFD1_k127_6776261_5 sulfur carrier activity K04085 - - 0.000000000000000000000002205 104.0
HFD1_k127_6776261_6 - - - - 0.000005754 49.0
HFD1_k127_6811573_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 291.0
HFD1_k127_6811573_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000001784 248.0
HFD1_k127_6811573_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000146 160.0
HFD1_k127_6811573_3 Tetratricopeptide repeat - - - 0.0008015 48.0
HFD1_k127_687_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 1.489e-285 927.0
HFD1_k127_687_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.305e-268 839.0
HFD1_k127_687_10 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 466.0
HFD1_k127_687_11 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 441.0
HFD1_k127_687_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 440.0
HFD1_k127_687_13 Glucose-1-phosphate thymidylyltransferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 432.0
HFD1_k127_687_14 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 429.0
HFD1_k127_687_15 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 433.0
HFD1_k127_687_16 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 428.0
HFD1_k127_687_17 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 422.0
HFD1_k127_687_18 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 419.0
HFD1_k127_687_19 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 413.0
HFD1_k127_687_2 Elongation factor G, domain IV K02355 - - 2.087e-217 683.0
HFD1_k127_687_20 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 337.0
HFD1_k127_687_21 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 328.0
HFD1_k127_687_22 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 322.0
HFD1_k127_687_23 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 316.0
HFD1_k127_687_24 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 310.0
HFD1_k127_687_25 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 293.0
HFD1_k127_687_26 Male sterility protein K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 289.0
HFD1_k127_687_27 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002923 276.0
HFD1_k127_687_28 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 258.0
HFD1_k127_687_29 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000003326 247.0
HFD1_k127_687_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.337e-213 669.0
HFD1_k127_687_30 Cytochrome c K16966,K17049,K17052 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000007079 259.0
HFD1_k127_687_31 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001011 209.0
HFD1_k127_687_32 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000002989 207.0
HFD1_k127_687_33 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000003886 199.0
HFD1_k127_687_34 YCII-related domain - - - 0.000000000000000000000000000000001881 132.0
HFD1_k127_687_35 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000007349 109.0
HFD1_k127_687_36 Addiction module toxin, RelE StbE family - - - 0.00000000000000000000000008308 108.0
HFD1_k127_687_37 PFAM Fibronectin, type III domain - - - 0.0000000001599 75.0
HFD1_k127_687_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.847e-212 666.0
HFD1_k127_687_5 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 608.0
HFD1_k127_687_6 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 508.0
HFD1_k127_687_7 Patatin-like phospholipase K06900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 488.0
HFD1_k127_687_8 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 491.0
HFD1_k127_687_9 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 475.0
HFD1_k127_6934174_0 response regulator receiver K07658,K07668 - - 0.0000000007716 68.0
HFD1_k127_6934174_1 amine dehydrogenase activity K01179,K03333,K12287 - 1.1.3.6,3.2.1.4 0.0000000118 62.0
HFD1_k127_6934174_3 cellulose binding - - - 0.00002218 57.0
HFD1_k127_7093232_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1785.0
HFD1_k127_7093232_1 HlyD membrane-fusion protein of T1SS K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 536.0
HFD1_k127_7093232_2 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 354.0
HFD1_k127_7093232_3 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009839 292.0
HFD1_k127_7093232_4 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000002585 142.0
HFD1_k127_7093232_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000634 122.0
HFD1_k127_7093232_6 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000000000002251 84.0
HFD1_k127_7093232_7 - - - - 0.00000000000004976 74.0
HFD1_k127_71409_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001082 241.0
HFD1_k127_71409_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000004492 138.0
HFD1_k127_71409_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000002845 83.0
HFD1_k127_71409_3 gluconolactonase activity - - - 0.00000000000001176 79.0
HFD1_k127_7167_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 421.0
HFD1_k127_7167_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000001113 222.0
HFD1_k127_7167_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000001356 208.0
HFD1_k127_7234404_0 Dehydratase family K01687 - 4.2.1.9 8.759e-260 810.0
HFD1_k127_7234404_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.693e-248 786.0
HFD1_k127_7234404_10 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 295.0
HFD1_k127_7234404_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001402 292.0
HFD1_k127_7234404_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000005636 259.0
HFD1_k127_7234404_13 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000004703 129.0
HFD1_k127_7234404_14 COG0223 Methionyl-tRNA formyltransferase - - - 0.00000000000000000000000000000005718 136.0
HFD1_k127_7234404_15 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000003612 109.0
HFD1_k127_7234404_16 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000003958 89.0
HFD1_k127_7234404_17 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.000000000003739 66.0
HFD1_k127_7234404_18 polysaccharide deacetylase - - - 0.00000000007538 73.0
HFD1_k127_7234404_19 - - - - 0.00005064 49.0
HFD1_k127_7234404_2 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.787e-240 760.0
HFD1_k127_7234404_3 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 1.303e-214 689.0
HFD1_k127_7234404_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 469.0
HFD1_k127_7234404_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 453.0
HFD1_k127_7234404_6 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 420.0
HFD1_k127_7234404_7 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 372.0
HFD1_k127_7234404_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 340.0
HFD1_k127_7234404_9 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 314.0
HFD1_k127_7262239_0 mannose-ethanolamine phosphotransferase activity K01176,K21571 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 316.0
HFD1_k127_7262239_1 Phage capsid family - - - 0.0000000000000000000000000000000000000000000004945 184.0
HFD1_k127_7321354_0 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 387.0
HFD1_k127_7321354_1 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 379.0
HFD1_k127_7321354_10 - - - - 0.00000000000000000000127 103.0
HFD1_k127_7321354_11 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000001582 102.0
HFD1_k127_7321354_12 Conserved region in glutamate synthase - - - 0.00000000001184 66.0
HFD1_k127_7321354_13 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000317 65.0
HFD1_k127_7321354_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001183 272.0
HFD1_k127_7321354_3 - - - - 0.000000000000000000000000000000000000000000000000000008273 192.0
HFD1_k127_7321354_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000001359 201.0
HFD1_k127_7321354_5 - - - - 0.000000000000000000000000000000000000000000000464 188.0
HFD1_k127_7321354_6 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000000000000000000000000006745 171.0
HFD1_k127_7321354_8 Nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000002381 117.0
HFD1_k127_7321354_9 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.000000000000000000000007985 112.0
HFD1_k127_7321870_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 501.0
HFD1_k127_7321870_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 454.0
HFD1_k127_7321870_10 response regulator, receiver - - - 0.000000000000000000000000001461 116.0
HFD1_k127_7321870_11 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000007676 70.0
HFD1_k127_7321870_12 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000002257 67.0
HFD1_k127_7321870_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 400.0
HFD1_k127_7321870_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 371.0
HFD1_k127_7321870_4 3-hydroxyacyl-CoA dehydrogenase K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 361.0
HFD1_k127_7321870_5 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 325.0
HFD1_k127_7321870_6 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 303.0
HFD1_k127_7321870_7 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 296.0
HFD1_k127_7321870_8 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006931 281.0
HFD1_k127_7321870_9 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000004192 243.0
HFD1_k127_7361887_0 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 486.0
HFD1_k127_7361887_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 325.0
HFD1_k127_7361887_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 296.0
HFD1_k127_7361887_3 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 287.0
HFD1_k127_7361887_4 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002567 273.0
HFD1_k127_7361887_5 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000000000000000679 198.0
HFD1_k127_7361887_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000004789 189.0
HFD1_k127_7361887_7 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000002082 158.0
HFD1_k127_7361887_8 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000007239 124.0
HFD1_k127_736667_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1254.0
HFD1_k127_736667_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1089.0
HFD1_k127_736667_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 419.0
HFD1_k127_736667_11 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 371.0
HFD1_k127_736667_12 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 366.0
HFD1_k127_736667_13 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 356.0
HFD1_k127_736667_14 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 336.0
HFD1_k127_736667_16 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 323.0
HFD1_k127_736667_17 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 309.0
HFD1_k127_736667_18 PFAM Glutamine amidotransferase, class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 292.0
HFD1_k127_736667_19 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004938 282.0
HFD1_k127_736667_2 DNA polymerase Ligase (LigD) - - - 7.937e-314 978.0
HFD1_k127_736667_20 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 281.0
HFD1_k127_736667_21 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001308 264.0
HFD1_k127_736667_22 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006744 256.0
HFD1_k127_736667_23 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000002306 246.0
HFD1_k127_736667_24 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009456 245.0
HFD1_k127_736667_25 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000001514 225.0
HFD1_k127_736667_26 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000003825 217.0
HFD1_k127_736667_27 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000006983 203.0
HFD1_k127_736667_28 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.0000000000000000000000000000000000000000000000003962 179.0
HFD1_k127_736667_29 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000003017 175.0
HFD1_k127_736667_3 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.116e-310 960.0
HFD1_k127_736667_30 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000002045 180.0
HFD1_k127_736667_31 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000001718 154.0
HFD1_k127_736667_32 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000729 139.0
HFD1_k127_736667_33 sulfur carrier activity - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0033554,GO:0042592,GO:0048878,GO:0050896,GO:0051716,GO:0055082,GO:0065007,GO:0065008 - 0.000000000000000000000008057 103.0
HFD1_k127_736667_35 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000008824 90.0
HFD1_k127_736667_36 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000007176 83.0
HFD1_k127_736667_37 Universal stress protein family - - - 0.000000000008055 71.0
HFD1_k127_736667_38 ACT domain protein - - - 0.000004795 54.0
HFD1_k127_736667_39 - - - - 0.000004884 52.0
HFD1_k127_736667_4 Protein involved in outer membrane biogenesis - - - 6.76e-273 880.0
HFD1_k127_736667_40 DSBA-like thioredoxin domain - - - 0.000729 44.0
HFD1_k127_736667_5 SMART Elongator protein 3 MiaB NifB - - - 1.359e-217 685.0
HFD1_k127_736667_6 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 484.0
HFD1_k127_736667_7 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 444.0
HFD1_k127_736667_8 Conserved region in glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 436.0
HFD1_k127_736667_9 Sulphur transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 436.0
HFD1_k127_7367144_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 362.0
HFD1_k127_7367144_1 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007833 270.0
HFD1_k127_7367144_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000002679 153.0
HFD1_k127_7367144_3 Glycosyl transferases group 1 - - - 0.000509 53.0
HFD1_k127_7376436_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 546.0
HFD1_k127_7376436_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 507.0
HFD1_k127_7376436_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 464.0
HFD1_k127_7376436_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 288.0
HFD1_k127_7376436_4 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000001377 257.0
HFD1_k127_7376436_5 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000003024 147.0
HFD1_k127_7376436_6 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000000002416 93.0
HFD1_k127_7404389_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 7.473e-227 713.0
HFD1_k127_7404389_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.2e-224 702.0
HFD1_k127_7404389_10 zinc ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001433 279.0
HFD1_k127_7404389_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000006287 210.0
HFD1_k127_7404389_12 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000827 209.0
HFD1_k127_7404389_13 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000001743 203.0
HFD1_k127_7404389_14 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000004526 169.0
HFD1_k127_7404389_15 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000001145 136.0
HFD1_k127_7404389_16 cyclic nucleotide binding K10914 - - 0.000000000000000000001971 97.0
HFD1_k127_7404389_17 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000002269 89.0
HFD1_k127_7404389_18 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000002596 81.0
HFD1_k127_7404389_19 lyase activity - - - 0.0000000000000002886 87.0
HFD1_k127_7404389_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 6.085e-203 652.0
HFD1_k127_7404389_20 Tetratricopeptide repeat-like domain - - - 0.0000000000000003185 87.0
HFD1_k127_7404389_21 competence protein - - - 0.0000001105 55.0
HFD1_k127_7404389_22 PilZ domain - - - 0.0000002132 59.0
HFD1_k127_7404389_23 - - - - 0.00000128 54.0
HFD1_k127_7404389_24 Evidence 5 No homology to any previously reported sequences - - - 0.00001094 49.0
HFD1_k127_7404389_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 564.0
HFD1_k127_7404389_4 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 537.0
HFD1_k127_7404389_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 530.0
HFD1_k127_7404389_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 520.0
HFD1_k127_7404389_7 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 404.0
HFD1_k127_7404389_8 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 361.0
HFD1_k127_7404389_9 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 331.0
HFD1_k127_7417065_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 9.734e-202 634.0
HFD1_k127_7417065_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 385.0
HFD1_k127_7417065_2 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 351.0
HFD1_k127_7417065_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 290.0
HFD1_k127_7417065_4 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000003272 241.0
HFD1_k127_7417065_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000007133 194.0
HFD1_k127_7417065_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000003576 171.0
HFD1_k127_7417065_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000007405 132.0
HFD1_k127_7417065_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000005097 119.0
HFD1_k127_7417065_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.0000000000000000000000000001605 119.0
HFD1_k127_7425898_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 8.801e-315 989.0
HFD1_k127_7425898_1 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 5.772e-216 682.0
HFD1_k127_7425898_10 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000003108 225.0
HFD1_k127_7425898_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000001795 192.0
HFD1_k127_7425898_12 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000002288 166.0
HFD1_k127_7425898_13 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000004861 122.0
HFD1_k127_7425898_14 Acyltransferase K00655 - 2.3.1.51 0.0000000000000006018 87.0
HFD1_k127_7425898_15 4Fe-4S binding domain - - - 0.000000000000002057 77.0
HFD1_k127_7425898_16 Cupin 2, conserved barrel domain protein - - - 0.0000000002237 65.0
HFD1_k127_7425898_18 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0004566 43.0
HFD1_k127_7425898_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 575.0
HFD1_k127_7425898_3 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 541.0
HFD1_k127_7425898_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 497.0
HFD1_k127_7425898_5 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 410.0
HFD1_k127_7425898_6 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 390.0
HFD1_k127_7425898_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000008827 259.0
HFD1_k127_7425898_8 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000005572 253.0
HFD1_k127_7425898_9 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000011 202.0
HFD1_k127_7442488_0 PFAM Radical SAM - - - 1.603e-198 630.0
HFD1_k127_7442488_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 591.0
HFD1_k127_7442488_10 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 301.0
HFD1_k127_7442488_11 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
HFD1_k127_7442488_12 transferase activity, transferring glycosyl groups K13500 - 2.4.1.175,2.4.1.226 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007239 275.0
HFD1_k127_7442488_13 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000206 205.0
HFD1_k127_7442488_14 protein tyrosine phosphatase activity K01104,K19302 - 3.1.3.48,3.6.1.27 0.0000000000000000000000000000000000000000000000001997 183.0
HFD1_k127_7442488_15 glycogen (starch) synthase activity - - - 0.00000000000000000000000000000000000000000001225 177.0
HFD1_k127_7442488_16 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000005015 171.0
HFD1_k127_7442488_17 AMP binding - - - 0.000000000000000000000000000000000000000008619 164.0
HFD1_k127_7442488_18 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000002057 128.0
HFD1_k127_7442488_19 thiolester hydrolase activity - - - 0.0000000000000000000000000000002184 127.0
HFD1_k127_7442488_2 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 565.0
HFD1_k127_7442488_20 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.0000000000000000000000000001021 122.0
HFD1_k127_7442488_21 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000001763 107.0
HFD1_k127_7442488_22 CYTH domain K05873 - 4.6.1.1 0.000000000000006191 81.0
HFD1_k127_7442488_23 O-antigen K02847 - - 0.000000000001153 80.0
HFD1_k127_7442488_24 UDP-glucose 4-epimerase K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000009988 59.0
HFD1_k127_7442488_25 Sodium/calcium exchanger protein K07301 - - 0.000001029 52.0
HFD1_k127_7442488_26 Tellurite resistance protein TehB - - - 0.00008544 47.0
HFD1_k127_7442488_3 ABC transporter, transmembrane region K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 510.0
HFD1_k127_7442488_4 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 490.0
HFD1_k127_7442488_5 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 452.0
HFD1_k127_7442488_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 353.0
HFD1_k127_7442488_7 Carbohydrate ABC transporter membrane protein 2, CUT1 family K02026,K17323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 354.0
HFD1_k127_7442488_8 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 345.0
HFD1_k127_7442488_9 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 315.0
HFD1_k127_7460975_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 484.0
HFD1_k127_7460975_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 408.0
HFD1_k127_7460975_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 373.0
HFD1_k127_7460975_3 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000005326 164.0
HFD1_k127_7460975_4 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000008339 149.0
HFD1_k127_7460975_5 Dienelactone hydrolase family - - - 0.0000000000001761 74.0
HFD1_k127_7499102_0 Iron-containing alcohol dehydrogenase K13954 - 1.1.1.1 1.551e-203 638.0
HFD1_k127_7499102_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000139 176.0
HFD1_k127_7499102_10 chlorophyll binding K03286,K03640 - - 0.0007555 45.0
HFD1_k127_7499102_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000003902 176.0
HFD1_k127_7499102_3 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000008118 168.0
HFD1_k127_7499102_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000006388 145.0
HFD1_k127_7499102_5 - - - - 0.000000000000000000000000000003196 127.0
HFD1_k127_7499102_6 domain, Protein K00703,K07082 - 2.4.1.21 0.000000000000000000006899 98.0
HFD1_k127_7499102_7 - - - - 0.0000000000000000001538 89.0
HFD1_k127_7499102_9 Protein of unknown function (DUF1573) - - - 0.000003497 51.0
HFD1_k127_7525_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.344e-307 953.0
HFD1_k127_7525_1 transporter antisigma-factor antagonist STAS K03321 - - 8.289e-217 687.0
HFD1_k127_7525_2 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 511.0
HFD1_k127_7525_3 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 453.0
HFD1_k127_7525_4 4Fe-4S dicluster domain K00196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005306 250.0
HFD1_k127_7525_5 Catalase - - - 0.00000000000000000000000000000739 120.0
HFD1_k127_7525_6 - - - - 0.0000000001354 61.0
HFD1_k127_7526064_0 FecR protein - - - 0.0 1125.0
HFD1_k127_7526064_1 CHASE2 K01768 - 4.6.1.1 6.894e-258 815.0
HFD1_k127_7531531_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1103.0
HFD1_k127_7531531_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1022.0
HFD1_k127_7531531_10 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000001634 192.0
HFD1_k127_7531531_11 protein with SCP PR1 domains - - - 0.00000000000000000000000000000000000000000000002365 178.0
HFD1_k127_7531531_12 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000002987 169.0
HFD1_k127_7531531_13 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000007266 132.0
HFD1_k127_7531531_15 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000001488 87.0
HFD1_k127_7531531_16 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000002334 81.0
HFD1_k127_7531531_17 electron transfer activity K05337,K17247 - - 0.0000000000000003374 79.0
HFD1_k127_7531531_18 SEC-C Motif Domain Protein - - - 0.00000000002344 73.0
HFD1_k127_7531531_2 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 612.0
HFD1_k127_7531531_21 - - - - 0.000003565 57.0
HFD1_k127_7531531_23 Cysteine-rich small domain - - - 0.00005724 46.0
HFD1_k127_7531531_3 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 554.0
HFD1_k127_7531531_4 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 370.0
HFD1_k127_7531531_5 HD domain K07023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 286.0
HFD1_k127_7531531_6 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007284 280.0
HFD1_k127_7531531_7 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000004829 254.0
HFD1_k127_7531531_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000219 246.0
HFD1_k127_7531531_9 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000009488 217.0
HFD1_k127_7547883_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1160.0
HFD1_k127_7547883_1 Peptidase family M28 - - - 0.0 1084.0
HFD1_k127_7547883_11 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000002793 90.0
HFD1_k127_7547883_12 Nitroreductase family - - - 0.0000000000000000008201 88.0
HFD1_k127_7547883_13 multicopper - - - 0.0000000000000313 77.0
HFD1_k127_7547883_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 579.0
HFD1_k127_7547883_3 Beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 526.0
HFD1_k127_7547883_4 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 355.0
HFD1_k127_7547883_5 Glycosyl hydrolases family 43 - - - 0.00000000000000000000000000000000000000000000000006116 190.0
HFD1_k127_7547883_6 - - - - 0.000000000000000000000000000000000000000000000004119 182.0
HFD1_k127_7547883_7 Diguanylate cyclase with PAS PAC sensor - - - 0.0000000000000000000000000000000000000002328 160.0
HFD1_k127_7547883_8 Nitroreductase family - - - 0.0000000000000000000000000000003361 124.0
HFD1_k127_7547883_9 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000006705 113.0
HFD1_k127_7574130_0 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 519.0
HFD1_k127_7574130_1 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 456.0
HFD1_k127_7574130_2 - - - - 0.000000000004507 72.0
HFD1_k127_7627238_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 451.0
HFD1_k127_7627238_1 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 366.0
HFD1_k127_7627238_2 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000314 284.0
HFD1_k127_7627238_3 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000089 273.0
HFD1_k127_7627238_4 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 246.0
HFD1_k127_7627238_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000005952 197.0
HFD1_k127_7627238_6 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.00000000000000000000000000000000001363 145.0
HFD1_k127_7627238_7 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000004947 130.0
HFD1_k127_7627238_9 deoxyhypusine monooxygenase activity - - - 0.0001491 49.0
HFD1_k127_7634823_0 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 541.0
HFD1_k127_7634823_1 LysM domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 333.0
HFD1_k127_7634823_2 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 303.0
HFD1_k127_7634823_3 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006388 254.0
HFD1_k127_7634823_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008776 248.0
HFD1_k127_7634823_5 AMP binding - - - 0.0000000000000000000000000000000000000000000000000003548 194.0
HFD1_k127_7634823_6 YceI-like domain - - - 0.000000000000000000000000000000000000002782 152.0
HFD1_k127_7634823_7 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000001689 137.0
HFD1_k127_7634823_8 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000001244 119.0
HFD1_k127_7634823_9 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000001425 108.0
HFD1_k127_7644757_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001085 266.0
HFD1_k127_7644757_1 histidine kinase, HAMP K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000001805 258.0
HFD1_k127_7644757_2 Hydrogenase maturation protease K03605 - - 0.00000000000000000000007083 101.0
HFD1_k127_7649549_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 520.0
HFD1_k127_7649549_1 PFAM peptidase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 409.0
HFD1_k127_7649549_2 Mur ligase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 317.0
HFD1_k127_7649549_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000001214 211.0
HFD1_k127_7649549_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000656 170.0
HFD1_k127_7649549_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000002964 147.0
HFD1_k127_7649549_6 HD domain protein - - - 0.000000000000000001185 97.0
HFD1_k127_7649549_7 PFAM ATP-binding region ATPase domain protein - - - 0.00000000006739 72.0
HFD1_k127_7821580_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 539.0
HFD1_k127_7821580_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005266 289.0
HFD1_k127_7821580_3 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.0000000000000000000000000000000000000000000000001343 187.0
HFD1_k127_7821580_4 Membrane - - - 0.00000000000000000000000008212 113.0
HFD1_k127_7822590_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.135e-203 640.0
HFD1_k127_7822590_1 Phosphoglycerate kinase K00927 - 2.7.2.3 1.698e-198 625.0
HFD1_k127_7822590_10 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 337.0
HFD1_k127_7822590_11 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 333.0
HFD1_k127_7822590_12 Cytochrome b5-like Heme/Steroid binding domain K07245,K14166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 298.0
HFD1_k127_7822590_13 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000198 284.0
HFD1_k127_7822590_14 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007043 273.0
HFD1_k127_7822590_15 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000009573 237.0
HFD1_k127_7822590_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003406 233.0
HFD1_k127_7822590_17 Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000001651 228.0
HFD1_k127_7822590_18 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000001948 222.0
HFD1_k127_7822590_19 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000000000000001219 210.0
HFD1_k127_7822590_2 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 608.0
HFD1_k127_7822590_20 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000005486 207.0
HFD1_k127_7822590_21 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0000000000000000000000000000000000000000000000000001009 186.0
HFD1_k127_7822590_22 - - - - 0.00000000000000000000000000000000000000000000000000357 192.0
HFD1_k127_7822590_23 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.00000000000000000000000000000000000000000000000006193 182.0
HFD1_k127_7822590_24 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000008179 175.0
HFD1_k127_7822590_25 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000000000000003678 179.0
HFD1_k127_7822590_26 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.00000000000000000000000000000000000000000000555 168.0
HFD1_k127_7822590_27 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000008696 134.0
HFD1_k127_7822590_28 Rhodanese Homology Domain - - - 0.0000000000000000000000006492 109.0
HFD1_k127_7822590_29 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000538 94.0
HFD1_k127_7822590_3 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 527.0
HFD1_k127_7822590_30 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000008313 79.0
HFD1_k127_7822590_31 Eco57I restriction-modification methylase - - - 0.00000000000000851 79.0
HFD1_k127_7822590_32 N-6 DNA Methylase - - - 0.00000000000002722 80.0
HFD1_k127_7822590_33 galactose-1-phosphate uridylyltransferase - - - 0.0000000000002595 70.0
HFD1_k127_7822590_34 heat shock protein binding K03686 - - 0.00000000002783 76.0
HFD1_k127_7822590_35 Protein of unknown function (DUF433) - - - 0.000000001611 63.0
HFD1_k127_7822590_37 Ferritin-like domain - - - 0.000003516 55.0
HFD1_k127_7822590_38 Protein of unknown function (DUF1573) - - - 0.00001147 49.0
HFD1_k127_7822590_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 473.0
HFD1_k127_7822590_40 DnaJ molecular chaperone homology domain - - - 0.00003289 56.0
HFD1_k127_7822590_41 HicA toxin of bacterial toxin-antitoxin, - - - 0.00004626 46.0
HFD1_k127_7822590_42 Protein of unknown function (DUF1573) - - - 0.0005817 44.0
HFD1_k127_7822590_5 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 451.0
HFD1_k127_7822590_6 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 446.0
HFD1_k127_7822590_7 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 400.0
HFD1_k127_7822590_8 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 392.0
HFD1_k127_7822590_9 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 387.0
HFD1_k127_7830224_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.518e-253 808.0
HFD1_k127_7830224_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 573.0
HFD1_k127_7830224_10 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
HFD1_k127_7830224_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000001021 177.0
HFD1_k127_7830224_12 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000297 163.0
HFD1_k127_7830224_13 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000009463 92.0
HFD1_k127_7830224_14 - - - - 0.0000000000000000000221 105.0
HFD1_k127_7830224_15 cell cycle K05589,K12065,K13052 - - 0.0000000000001232 74.0
HFD1_k127_7830224_16 Belongs to the LarC family K09121 - 4.99.1.12 0.00000004132 61.0
HFD1_k127_7830224_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 488.0
HFD1_k127_7830224_3 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 476.0
HFD1_k127_7830224_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 440.0
HFD1_k127_7830224_5 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 430.0
HFD1_k127_7830224_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 391.0
HFD1_k127_7830224_7 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 379.0
HFD1_k127_7830224_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 380.0
HFD1_k127_7830224_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000553 288.0
HFD1_k127_7939741_0 PFAM alpha amylase, catalytic K06044 - 5.4.99.15 0.0 1121.0
HFD1_k127_7939741_1 Alpha amylase, catalytic domain K01176,K01236 - 3.2.1.1,3.2.1.141 1.138e-258 810.0
HFD1_k127_7939741_10 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 424.0
HFD1_k127_7939741_11 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 419.0
HFD1_k127_7939741_12 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 409.0
HFD1_k127_7939741_13 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 400.0
HFD1_k127_7939741_14 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 394.0
HFD1_k127_7939741_15 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 352.0
HFD1_k127_7939741_16 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 353.0
HFD1_k127_7939741_17 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 339.0
HFD1_k127_7939741_18 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 332.0
HFD1_k127_7939741_19 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
HFD1_k127_7939741_2 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 4.478e-247 784.0
HFD1_k127_7939741_20 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002898 282.0
HFD1_k127_7939741_21 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009034 277.0
HFD1_k127_7939741_22 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004803 259.0
HFD1_k127_7939741_23 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001232 253.0
HFD1_k127_7939741_24 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002293 244.0
HFD1_k127_7939741_25 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000001384 242.0
HFD1_k127_7939741_26 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000001993 195.0
HFD1_k127_7939741_27 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000001482 173.0
HFD1_k127_7939741_28 HNH nucleases - - - 0.0000000000000000000000000000000000000000000001674 170.0
HFD1_k127_7939741_29 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000009195 174.0
HFD1_k127_7939741_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 608.0
HFD1_k127_7939741_30 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000001159 153.0
HFD1_k127_7939741_31 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000002444 141.0
HFD1_k127_7939741_32 Transcriptional regulator, MerR family - - - 0.00000000000000000000000000000000004367 138.0
HFD1_k127_7939741_33 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000002461 117.0
HFD1_k127_7939741_34 TIGRFAM 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000000001016 113.0
HFD1_k127_7939741_35 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000001012 99.0
HFD1_k127_7939741_36 diguanylate cyclase K21022 - 2.7.7.65 0.000000000000000004053 99.0
HFD1_k127_7939741_37 phosphorelay sensor kinase activity - - - 0.00000001029 68.0
HFD1_k127_7939741_38 CAAX protease self-immunity - - - 0.0000006786 58.0
HFD1_k127_7939741_4 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 608.0
HFD1_k127_7939741_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 573.0
HFD1_k127_7939741_6 pathogenesis K13669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 602.0
HFD1_k127_7939741_7 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 482.0
HFD1_k127_7939741_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 454.0
HFD1_k127_7939741_9 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 428.0
HFD1_k127_814784_0 Protein of unknown function (DUF1254) - - - 1.696e-203 644.0
HFD1_k127_814784_1 Sigma-54 interaction domain K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 431.0
HFD1_k127_814784_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 309.0
HFD1_k127_814784_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002391 278.0
HFD1_k127_814784_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000004809 259.0
HFD1_k127_814784_5 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000002257 132.0
HFD1_k127_814784_6 OsmC-like protein - - - 0.000000000000000000001907 100.0
HFD1_k127_814784_7 Transposase (IS116 IS110 IS902 family) - - - 0.000000001309 62.0
HFD1_k127_814784_8 Protein of unknown function (DUF2934) - - - 0.0000001196 57.0
HFD1_k127_840604_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 582.0
HFD1_k127_840604_1 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 563.0
HFD1_k127_840604_2 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 319.0
HFD1_k127_840604_3 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005139 232.0
HFD1_k127_840604_4 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.000000000000000000000000000007454 125.0
HFD1_k127_840604_5 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000004083 76.0
HFD1_k127_840604_6 Domain of unknown function (DUF2703) - - - 0.0000000004954 60.0
HFD1_k127_855177_0 Surface antigen K07277 - - 8.635e-260 822.0
HFD1_k127_855177_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 572.0
HFD1_k127_855177_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000002785 201.0
HFD1_k127_855177_11 heme-binding sites - - - 0.00000000000000000000000000000000000005372 152.0
HFD1_k127_855177_12 tetratricopeptide repeat - - - 0.00000000000000000000000000000000001019 143.0
HFD1_k127_855177_13 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000001572 144.0
HFD1_k127_855177_14 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000007585 124.0
HFD1_k127_855177_15 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000211 92.0
HFD1_k127_855177_16 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000001485 86.0
HFD1_k127_855177_17 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000001368 78.0
HFD1_k127_855177_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 500.0
HFD1_k127_855177_3 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 422.0
HFD1_k127_855177_4 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 400.0
HFD1_k127_855177_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 378.0
HFD1_k127_855177_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 357.0
HFD1_k127_855177_7 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000484 261.0
HFD1_k127_855177_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000009288 209.0
HFD1_k127_855177_9 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000001551 187.0
HFD1_k127_876779_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000001014 217.0
HFD1_k127_876779_1 CsbD-like - - - 0.000000000000000000000001384 105.0
HFD1_k127_876779_2 Domain of unknown function (DUF4833) - - - 0.00000000000000000000001108 109.0
HFD1_k127_876779_3 Membrane - - - 0.0000000000000000002299 94.0
HFD1_k127_876779_4 - - - - 0.0000000001979 62.0
HFD1_k127_879339_0 FtsX-like permease family K02004 - - 2.818e-310 968.0
HFD1_k127_879339_1 Ftsk_gamma K03466 - - 6.432e-208 668.0
HFD1_k127_879339_2 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 458.0
HFD1_k127_879339_3 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 348.0
HFD1_k127_879339_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 286.0
HFD1_k127_879339_5 HD domain - - - 0.000000000000000000000000000000000000000000006252 178.0
HFD1_k127_879339_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000001979 161.0
HFD1_k127_879339_7 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000003299 152.0
HFD1_k127_879339_8 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000005329 82.0
HFD1_k127_879339_9 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000001027 55.0
HFD1_k127_88176_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1278.0
HFD1_k127_88176_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 9.359e-272 848.0
HFD1_k127_88176_10 Polymorphic membrane protein Chlamydia - - - 0.0000000000000000000000000000000000000000000000000000000000004302 242.0
HFD1_k127_88176_11 Endonuclease V K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000005013 194.0
HFD1_k127_88176_12 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000007572 173.0
HFD1_k127_88176_13 alginic acid biosynthetic process K12287 - - 0.00000000000000007823 96.0
HFD1_k127_88176_14 SEC-C motif - - - 0.00000002263 57.0
HFD1_k127_88176_15 - - - - 0.00000008033 55.0
HFD1_k127_88176_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 459.0
HFD1_k127_88176_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 430.0
HFD1_k127_88176_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 422.0
HFD1_k127_88176_5 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 373.0
HFD1_k127_88176_6 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 312.0
HFD1_k127_88176_7 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 277.0
HFD1_k127_88176_8 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001154 262.0
HFD1_k127_88176_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000007788 261.0
HFD1_k127_9353_0 transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000002143 201.0
HFD1_k127_9353_1 - - - - 0.00000000000000000000000000000000000000006651 162.0
HFD1_k127_9353_2 Transposase - - - 0.0000000000000000000006639 96.0
HFD1_k127_9353_3 - - - - 0.00000002173 61.0
HFD1_k127_9895_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.082e-265 826.0
HFD1_k127_9895_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 473.0
HFD1_k127_9895_2 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 383.0
HFD1_k127_9895_3 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 383.0
HFD1_k127_9895_4 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000256 274.0
HFD1_k127_996857_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 614.0
HFD1_k127_996857_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 559.0
HFD1_k127_996857_10 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000051 265.0
HFD1_k127_996857_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008906 249.0
HFD1_k127_996857_12 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000004719 257.0
HFD1_k127_996857_13 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000002876 252.0
HFD1_k127_996857_14 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000329 219.0
HFD1_k127_996857_15 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000219 171.0
HFD1_k127_996857_16 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000000000000000000000000008357 137.0
HFD1_k127_996857_17 Papain family cysteine protease - - - 0.000000000000000000000000000000007491 133.0
HFD1_k127_996857_18 Histidine kinase - - - 0.000000000000000000000002983 114.0
HFD1_k127_996857_19 Belongs to the UPF0235 family K09131 - - 0.0000000000000002486 81.0
HFD1_k127_996857_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 523.0
HFD1_k127_996857_20 PFAM Beta propeller domain K14475 - - 0.000000004214 63.0
HFD1_k127_996857_22 - - - - 0.00002151 56.0
HFD1_k127_996857_24 ATP-independent chaperone mediated protein folding - - - 0.0001669 51.0
HFD1_k127_996857_25 Putative phosphatase (DUF442) - - - 0.0002372 48.0
HFD1_k127_996857_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 466.0
HFD1_k127_996857_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 419.0
HFD1_k127_996857_5 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 390.0
HFD1_k127_996857_6 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 387.0
HFD1_k127_996857_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 382.0
HFD1_k127_996857_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 375.0
HFD1_k127_996857_9 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 346.0