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Overview

ID MAG01620
Name HFD1_bin.3
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Nitrospiria
Order Nitrospirales
Family Nitrospiraceae
Genus Nitrospira_C
Species
Assembly information
Completeness (%) 80.1
Contamination (%) 5.24
GC content (%) 57.0
N50 (bp) 15,363
Genome size (bp) 2,956,001

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2590

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1023174_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.558e-320 983.0
HFD1_k127_1023174_1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.00000000000000000000000000000000000000000000000000000000001233 208.0
HFD1_k127_1023174_2 - - - - 0.0000000000000000000000000000000000000000000000000000004292 194.0
HFD1_k127_1023174_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000000000005898 179.0
HFD1_k127_1158064_0 siderophore transport K02014 - - 0.0 1093.0
HFD1_k127_1158064_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 6.873e-234 732.0
HFD1_k127_1158064_10 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 332.0
HFD1_k127_1158064_11 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 310.0
HFD1_k127_1158064_12 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 306.0
HFD1_k127_1158064_13 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001138 279.0
HFD1_k127_1158064_14 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000003171 242.0
HFD1_k127_1158064_15 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000004311 239.0
HFD1_k127_1158064_17 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000003351 201.0
HFD1_k127_1158064_18 YacP-like NYN domain K06962 - - 0.000000000000000000000000004534 117.0
HFD1_k127_1158064_19 phosphate starvation-inducible protein, PsiF - - - 0.00000000000000000000000466 105.0
HFD1_k127_1158064_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 565.0
HFD1_k127_1158064_3 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 541.0
HFD1_k127_1158064_4 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 535.0
HFD1_k127_1158064_5 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 429.0
HFD1_k127_1158064_6 cobalamin synthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 417.0
HFD1_k127_1158064_7 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 399.0
HFD1_k127_1158064_8 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 372.0
HFD1_k127_1158064_9 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 346.0
HFD1_k127_1221133_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 516.0
HFD1_k127_1221133_1 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 389.0
HFD1_k127_1228312_0 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 376.0
HFD1_k127_1228312_1 helix_turn _helix lactose operon repressor K05499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 317.0
HFD1_k127_1246023_0 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 303.0
HFD1_k127_1246023_1 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 301.0
HFD1_k127_1246023_2 IMP dehydrogenase activity K07182 - - 0.000000000000000000000000000000000000000000000000000000006631 204.0
HFD1_k127_1246023_4 IMP dehydrogenase activity K07182 - - 0.00000000000000000000000000000000000005273 148.0
HFD1_k127_1249271_0 AcrB/AcrD/AcrF family - - - 0.0 1666.0
HFD1_k127_1249271_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 3.456e-250 774.0
HFD1_k127_1249271_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 542.0
HFD1_k127_1249271_3 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 428.0
HFD1_k127_1249271_5 - - - - 0.000000000000000000000000000000000000000000000000000000000001797 214.0
HFD1_k127_1249271_6 Cytochrome c K12263 - - 0.00000000000000000000000000006781 120.0
HFD1_k127_127217_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1148.0
HFD1_k127_127217_1 Aminotransferase class I and II K14261 - - 1.713e-233 724.0
HFD1_k127_127217_11 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000651 149.0
HFD1_k127_127217_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 7.391e-224 705.0
HFD1_k127_127217_3 Homoserine dehydrogenase K00003 - 1.1.1.3 5.066e-211 664.0
HFD1_k127_127217_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 604.0
HFD1_k127_127217_5 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 526.0
HFD1_k127_127217_6 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 488.0
HFD1_k127_127217_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 381.0
HFD1_k127_1345822_0 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 363.0
HFD1_k127_1345822_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000001349 244.0
HFD1_k127_1345822_2 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.000000000000000000000000000000000000000000000000000000000000002309 220.0
HFD1_k127_1345822_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000001681 220.0
HFD1_k127_1345822_4 polyphosphate kinase activity K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000006178 207.0
HFD1_k127_1345822_5 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000001764 94.0
HFD1_k127_1345822_6 Cytochrome c K12263 - - 0.0000000000000002035 78.0
HFD1_k127_1347347_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1967.0
HFD1_k127_1347347_1 AcrB/AcrD/AcrF family K15726 - - 0.0 1628.0
HFD1_k127_1347347_10 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 472.0
HFD1_k127_1347347_11 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 471.0
HFD1_k127_1347347_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 476.0
HFD1_k127_1347347_13 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 415.0
HFD1_k127_1347347_14 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 403.0
HFD1_k127_1347347_15 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 403.0
HFD1_k127_1347347_16 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 379.0
HFD1_k127_1347347_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 363.0
HFD1_k127_1347347_18 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 339.0
HFD1_k127_1347347_19 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 333.0
HFD1_k127_1347347_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 2.804e-251 777.0
HFD1_k127_1347347_20 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 327.0
HFD1_k127_1347347_21 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 319.0
HFD1_k127_1347347_22 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002249 280.0
HFD1_k127_1347347_23 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001134 274.0
HFD1_k127_1347347_24 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004218 271.0
HFD1_k127_1347347_26 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006349 234.0
HFD1_k127_1347347_27 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000000000000000001018 223.0
HFD1_k127_1347347_28 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000000000000000000000000000000000000000000001146 227.0
HFD1_k127_1347347_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 6.76e-239 751.0
HFD1_k127_1347347_31 - - - - 0.000000000000000000000000000000000000000000212 166.0
HFD1_k127_1347347_34 ThiS family K03636 - - 0.000000000000000000000000000000000000000003453 155.0
HFD1_k127_1347347_35 NIL - - - 0.00000000000000000000000000000000000149 139.0
HFD1_k127_1347347_36 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.000000000000000000000000000000000001862 140.0
HFD1_k127_1347347_39 Regulatory protein, FmdB family - - - 0.00000000000000000000000000003791 123.0
HFD1_k127_1347347_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.505e-216 680.0
HFD1_k127_1347347_42 thiamine diphosphate biosynthetic process K03154 - - 0.000000000000000000000004229 103.0
HFD1_k127_1347347_45 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.000000000000000000009495 96.0
HFD1_k127_1347347_47 metallopeptidase activity K01637 - 4.1.3.1 0.000000000000000001751 96.0
HFD1_k127_1347347_48 nuclease - - - 0.00000000000000001105 84.0
HFD1_k127_1347347_49 PFAM nuclease (SNase domain protein) - - - 0.00000000000000001632 83.0
HFD1_k127_1347347_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 606.0
HFD1_k127_1347347_50 Cytochrome c K02305,K17223 - - 0.000000000000000226 89.0
HFD1_k127_1347347_54 Helix-hairpin-helix motif - - - 0.0000000239 55.0
HFD1_k127_1347347_6 response regulator K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 584.0
HFD1_k127_1347347_7 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 580.0
HFD1_k127_1347347_8 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 554.0
HFD1_k127_1347347_9 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 559.0
HFD1_k127_1349793_0 Endoribonuclease that initiates mRNA decay K18682 - - 5.346e-263 818.0
HFD1_k127_1349793_1 Transglycosylase SLT domain K08309 - - 5.893e-253 801.0
HFD1_k127_1349793_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 442.0
HFD1_k127_1349793_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 426.0
HFD1_k127_1349793_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000221 131.0
HFD1_k127_1349793_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000816 97.0
HFD1_k127_1350952_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 444.0
HFD1_k127_1350952_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000005242 179.0
HFD1_k127_1350952_2 YHS domain protein - - - 0.0000000000000000000000000000000000000000001812 166.0
HFD1_k127_1350952_3 - - - - 0.000000000000000000000000000000000005924 143.0
HFD1_k127_1350952_4 transmembrane signaling receptor activity - - - 0.000000000000000000000000000000002553 137.0
HFD1_k127_1350952_7 Protein of unknown function (DUF1566) - - - 0.00000001742 63.0
HFD1_k127_1501188_0 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 412.0
HFD1_k127_1501188_1 ORF6N domain - - - 0.000000000000000000000000000000000000000000000000000000007345 202.0
HFD1_k127_1501188_2 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000001598 169.0
HFD1_k127_1501188_3 nickel cation binding K03190 - - 0.0000000000000000000000000002009 126.0
HFD1_k127_1521730_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1060.0
HFD1_k127_1521730_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 3.056e-209 654.0
HFD1_k127_1521730_10 protein homooligomerization - - - 0.000000000000000007273 94.0
HFD1_k127_1521730_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000005587 91.0
HFD1_k127_1521730_12 - - - - 0.0000000003214 61.0
HFD1_k127_1521730_13 flagellar motor K02557 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0006215 44.0
HFD1_k127_1521730_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K00387 - 1.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 571.0
HFD1_k127_1521730_3 sulfuric ester hydrolase activity K01002,K01138 - 2.7.8.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 537.0
HFD1_k127_1521730_4 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 464.0
HFD1_k127_1521730_5 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 396.0
HFD1_k127_1521730_6 ATPase activity K02013,K02028,K05776 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 340.0
HFD1_k127_1521730_7 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 297.0
HFD1_k127_1521730_8 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000002799 89.0
HFD1_k127_1521730_9 - - - - 0.00000000000000000006252 91.0
HFD1_k127_1580531_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 480.0
HFD1_k127_1580531_1 pectinesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 435.0
HFD1_k127_1580531_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 409.0
HFD1_k127_1580531_3 Zinc-uptake complex component A periplasmic K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 357.0
HFD1_k127_1580531_4 AAA domain, putative AbiEii toxin, Type IV TA system K09817,K09820 - - 0.000000000000000000000000000000000000000000000000000000000000001557 221.0
HFD1_k127_1580531_5 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000003129 199.0
HFD1_k127_1580531_8 zinc ion binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000004244 53.0
HFD1_k127_1590502_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 9.373e-318 983.0
HFD1_k127_1590502_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 1.663e-264 823.0
HFD1_k127_1590502_10 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002135 220.0
HFD1_k127_1590502_12 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000003236 153.0
HFD1_k127_1590502_13 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00001098 48.0
HFD1_k127_1590502_2 Rieske (2fe-2S) - - - 3.039e-203 637.0
HFD1_k127_1590502_3 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 554.0
HFD1_k127_1590502_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 539.0
HFD1_k127_1590502_5 Formiminotransferase domain K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 496.0
HFD1_k127_1590502_6 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 463.0
HFD1_k127_1590502_7 uroporphyrinogen-III synthase activity K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 341.0
HFD1_k127_1590502_8 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 311.0
HFD1_k127_1590502_9 phosphonoacetaldehyde hydrolase activity K01091,K07025,K19270 - 3.1.3.18,3.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000001352 250.0
HFD1_k127_159777_0 Type II/IV secretion system protein K02454,K02652 - - 2.393e-235 744.0
HFD1_k127_159777_1 Pilus assembly protein PilX K07140 - - 0.000000000000003576 77.0
HFD1_k127_1598924_0 Formate--tetrahydrofolate ligase K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 3.329e-280 870.0
HFD1_k127_1598924_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 564.0
HFD1_k127_1598924_2 stress-induced mitochondrial fusion K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 558.0
HFD1_k127_1598924_3 stress-induced mitochondrial fusion K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 461.0
HFD1_k127_1598924_4 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 444.0
HFD1_k127_1598924_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000004486 139.0
HFD1_k127_1598924_6 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.0000000000000000000000007858 108.0
HFD1_k127_1605749_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 6.359e-234 731.0
HFD1_k127_1605749_1 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 548.0
HFD1_k127_1605749_2 coenzyme binding K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 409.0
HFD1_k127_1605749_3 sirohydrochlorin cobaltochelatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000603 270.0
HFD1_k127_1605749_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000005021 142.0
HFD1_k127_1657737_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 420.0
HFD1_k127_1657737_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002084 274.0
HFD1_k127_1657737_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000003155 201.0
HFD1_k127_1657737_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000006076 116.0
HFD1_k127_1671681_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 9.91e-280 866.0
HFD1_k127_1671681_1 Evidence 2b Function of strongly homologous gene - - - 1.184e-269 844.0
HFD1_k127_1671681_10 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 353.0
HFD1_k127_1671681_11 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000002657 198.0
HFD1_k127_1671681_12 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000000003308 160.0
HFD1_k127_1671681_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 4.468e-260 811.0
HFD1_k127_1671681_3 Major Facilitator Superfamily K03446 - - 1.731e-215 680.0
HFD1_k127_1671681_4 peptidyl-tyrosine sulfation - - - 6.691e-215 681.0
HFD1_k127_1671681_5 Metallopeptidase family M24 K01262 - 3.4.11.9 5.603e-201 630.0
HFD1_k127_1671681_6 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009494 589.0
HFD1_k127_1671681_7 Multicopper oxidase K00368,K22349 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 542.0
HFD1_k127_1671681_8 formate transmembrane transporter activity K02598,K06212,K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 410.0
HFD1_k127_1671681_9 Protein involved in outer membrane biogenesis K07290 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 391.0
HFD1_k127_1699575_0 protein secretion by the type I secretion system K02021 - - 3.775e-287 889.0
HFD1_k127_1699575_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 1.559e-261 811.0
HFD1_k127_1699575_10 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 379.0
HFD1_k127_1699575_11 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 362.0
HFD1_k127_1699575_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 317.0
HFD1_k127_1699575_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000001521 237.0
HFD1_k127_1699575_14 signal-transduction protein containing cAMP-binding and CBS domains K00031,K14446 - 1.1.1.42,1.3.1.85 0.00000000000000000000000000000000000000000000000000000000000000002117 233.0
HFD1_k127_1699575_2 efflux transmembrane transporter activity - - - 1.487e-232 730.0
HFD1_k127_1699575_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 557.0
HFD1_k127_1699575_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 518.0
HFD1_k127_1699575_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 471.0
HFD1_k127_1699575_6 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 457.0
HFD1_k127_1699575_7 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 449.0
HFD1_k127_1699575_8 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 445.0
HFD1_k127_1699575_9 Protein of unknown function (DUF692) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 458.0
HFD1_k127_1702024_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1542.0
HFD1_k127_1702024_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.859e-259 818.0
HFD1_k127_1702024_10 2 iron, 2 sulfur cluster binding K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000001228 223.0
HFD1_k127_1702024_14 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000182 64.0
HFD1_k127_1702024_2 MFS_1 like family - - - 1.853e-198 625.0
HFD1_k127_1702024_3 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 543.0
HFD1_k127_1702024_4 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 528.0
HFD1_k127_1702024_5 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 334.0
HFD1_k127_1702024_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 345.0
HFD1_k127_1702024_7 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 327.0
HFD1_k127_1702024_9 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000007291 226.0
HFD1_k127_1706171_0 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 337.0
HFD1_k127_1706171_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 305.0
HFD1_k127_1706171_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000001467 209.0
HFD1_k127_1706171_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.000000000000000000000000000000000000000000000000000000002416 211.0
HFD1_k127_1706171_4 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000006048 190.0
HFD1_k127_1706171_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000003727 175.0
HFD1_k127_1706171_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000362 76.0
HFD1_k127_1714996_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 344.0
HFD1_k127_1714996_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001124 250.0
HFD1_k127_1714996_3 DsrE/DsrF-like family K09004 - - 0.000000000000001214 84.0
HFD1_k127_1714996_4 Histidine kinase - - - 0.00000000000172 68.0
HFD1_k127_1736435_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342,K05575 - 1.6.5.3 6.828e-297 917.0
HFD1_k127_1736435_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 3.816e-265 823.0
HFD1_k127_1736435_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.694e-257 800.0
HFD1_k127_1736435_3 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 1.905e-225 705.0
HFD1_k127_1736435_4 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 584.0
HFD1_k127_1736435_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007196 265.0
HFD1_k127_1742389_0 protein related to plant photosystem II stability assembly factor - - - 2.617e-196 618.0
HFD1_k127_1742389_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 359.0
HFD1_k127_1742389_3 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000001721 135.0
HFD1_k127_1742389_4 ThiS family K03636 - - 0.0000000000000000000006199 99.0
HFD1_k127_1742389_5 TfoX N-terminal domain K07343 - - 0.00000000000000000207 90.0
HFD1_k127_1768060_0 'PFAM Alpha amylase, catalytic K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 490.0
HFD1_k127_1768060_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 331.0
HFD1_k127_1768060_2 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.000000000000000000000000000000000000000000000000000000000000000000000000000000112 268.0
HFD1_k127_1777729_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 567.0
HFD1_k127_1777729_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 435.0
HFD1_k127_1777729_2 AMP binding K11932 - - 0.0000000000000000001463 94.0
HFD1_k127_1777729_3 BNR repeat-like domain - - - 0.00000000001597 76.0
HFD1_k127_1782450_0 AcrB/AcrD/AcrF family - - - 0.0 1024.0
HFD1_k127_1782450_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 370.0
HFD1_k127_1782450_3 response regulator K03413 - - 0.0000000000004712 78.0
HFD1_k127_1803001_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1749.0
HFD1_k127_1803001_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 8.134e-228 714.0
HFD1_k127_1803001_2 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 426.0
HFD1_k127_1803001_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 366.0
HFD1_k127_1803001_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002852 259.0
HFD1_k127_1803001_6 Peptidase family S49 K04773 - - 0.000000000000000001561 85.0
HFD1_k127_1848748_0 - - - - 2.012e-278 863.0
HFD1_k127_1848748_1 - - - - 4.806e-262 820.0
HFD1_k127_1848748_11 response regulator K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 504.0
HFD1_k127_1848748_12 ATPase activity K02017,K02018,K03750,K15497 - 2.10.1.1,3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 492.0
HFD1_k127_1848748_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 481.0
HFD1_k127_1848748_14 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 438.0
HFD1_k127_1848748_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 429.0
HFD1_k127_1848748_16 resolution of meiotic recombination intermediates K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 419.0
HFD1_k127_1848748_17 tungstate binding K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 406.0
HFD1_k127_1848748_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 394.0
HFD1_k127_1848748_19 ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 400.0
HFD1_k127_1848748_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.309e-250 783.0
HFD1_k127_1848748_20 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 386.0
HFD1_k127_1848748_21 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 392.0
HFD1_k127_1848748_23 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 372.0
HFD1_k127_1848748_24 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 364.0
HFD1_k127_1848748_25 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 340.0
HFD1_k127_1848748_26 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K11206,K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 342.0
HFD1_k127_1848748_27 tungstate binding K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 339.0
HFD1_k127_1848748_29 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 330.0
HFD1_k127_1848748_3 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 9.655e-250 779.0
HFD1_k127_1848748_30 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 299.0
HFD1_k127_1848748_32 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 284.0
HFD1_k127_1848748_33 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001271 266.0
HFD1_k127_1848748_35 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000551 242.0
HFD1_k127_1848748_36 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000001589 240.0
HFD1_k127_1848748_37 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000008307 230.0
HFD1_k127_1848748_38 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000000000000000000116 206.0
HFD1_k127_1848748_39 tungstate binding K02020 - - 0.0000000000000000000000000000000000000000000000000000008553 203.0
HFD1_k127_1848748_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 4.871e-244 758.0
HFD1_k127_1848748_41 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000003834 192.0
HFD1_k127_1848748_42 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000004079 185.0
HFD1_k127_1848748_44 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000009703 172.0
HFD1_k127_1848748_46 negative regulation of translational initiation - - - 0.00000000000000000000000000000006457 133.0
HFD1_k127_1848748_47 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000000061 121.0
HFD1_k127_1848748_48 TPR repeat-containing protein - - - 0.000000000000000000000000000361 125.0
HFD1_k127_1848748_49 Protein of unknown function (DUF507) - - - 0.00000000000000000000000001873 110.0
HFD1_k127_1848748_5 peptidyl-tyrosine sulfation - - - 4.161e-217 688.0
HFD1_k127_1848748_50 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000000001382 100.0
HFD1_k127_1848748_51 molybdate ion transport K02019 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000007507 81.0
HFD1_k127_1848748_53 Uncharacterized small protein (DUF2292) - - - 0.000000001003 61.0
HFD1_k127_1848748_54 Histidine kinase K07777 - 2.7.13.3 0.0000543 48.0
HFD1_k127_1848748_6 Outer membrane efflux protein - - - 2.093e-216 684.0
HFD1_k127_1848748_7 Domain of unknown function (DUF4070) - - - 1.082e-197 631.0
HFD1_k127_1848748_8 Phosphate acyltransferases - - - 4.318e-195 620.0
HFD1_k127_1848748_9 phosphorelay sensor kinase activity K02038,K02282,K07018,K07315 - 3.1.3.3 1.118e-194 659.0
HFD1_k127_1910172_0 signal-transduction protein containing cAMP-binding and CBS domains K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 308.0
HFD1_k127_1910172_1 LmbE family - - - 0.000000000000000009264 83.0
HFD1_k127_1910172_2 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.00000000000000002367 85.0
HFD1_k127_1951772_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 2.293e-217 678.0
HFD1_k127_1951772_1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 2.619e-201 632.0
HFD1_k127_1951772_10 Belongs to the BolA IbaG family K05527,K22066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0019538,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051604,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097428,GO:0097659,GO:0106035,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.0000000000000000000000001322 108.0
HFD1_k127_1951772_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 596.0
HFD1_k127_1951772_3 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 402.0
HFD1_k127_1951772_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 339.0
HFD1_k127_1951772_5 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 304.0
HFD1_k127_1951772_6 protein disulfide oxidoreductase activity K07390 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.0000000000000000000000000000000000000000000000000000000191 198.0
HFD1_k127_1951772_9 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000000001717 127.0
HFD1_k127_19857_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 405.0
HFD1_k127_19857_1 Radical SAM superfamily K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 400.0
HFD1_k127_19857_10 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000006833 174.0
HFD1_k127_19857_11 zinc metalloprotease whose natural substrate is K06974 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000009993 129.0
HFD1_k127_19857_12 - - - - 0.0000000000000000000000008436 106.0
HFD1_k127_19857_13 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000001074 84.0
HFD1_k127_19857_14 DnaK suppressor protein - - - 0.0000000001067 67.0
HFD1_k127_19857_2 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 382.0
HFD1_k127_19857_3 PFAM amino acid permease-associated region K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 338.0
HFD1_k127_19857_4 Hydrogenase expression formation protein (HypE) K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 307.0
HFD1_k127_19857_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000285 286.0
HFD1_k127_19857_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003945 247.0
HFD1_k127_19857_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000009946 248.0
HFD1_k127_19857_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000911 228.0
HFD1_k127_19857_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000003909 178.0
HFD1_k127_1993062_0 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 516.0
HFD1_k127_1993062_1 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 372.0
HFD1_k127_1993062_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.000000000000000000000000000000000000000000000007658 172.0
HFD1_k127_2019370_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1161.0
HFD1_k127_2019370_1 Cytochrome c K00405 - - 4.25e-322 993.0
HFD1_k127_2019370_12 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000003602 223.0
HFD1_k127_2019370_13 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000001389 181.0
HFD1_k127_2019370_14 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000000006941 159.0
HFD1_k127_2019370_2 aerobic electron transport chain K00425,K08738 - 1.10.3.14 1.156e-302 938.0
HFD1_k127_2019370_3 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 1.464e-267 834.0
HFD1_k127_2019370_4 Cytochrome c K00405 - - 3.033e-217 680.0
HFD1_k127_2019370_5 Cytochrome c - - - 9.66e-200 624.0
HFD1_k127_2019370_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 546.0
HFD1_k127_2019370_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 441.0
HFD1_k127_2019370_8 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 431.0
HFD1_k127_2019370_9 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 423.0
HFD1_k127_2040947_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 1386.0
HFD1_k127_2040947_1 amino acid - - - 8.606e-280 871.0
HFD1_k127_2040947_3 actin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 497.0
HFD1_k127_2040947_4 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 421.0
HFD1_k127_2040947_5 2OG-Fe(II) oxygenase superfamily K07394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 328.0
HFD1_k127_2040947_6 RNA recognition motif - - - 0.0000000000000000000000000000000000000000005124 162.0
HFD1_k127_2040947_7 Response regulator, receiver - - - 0.000000000000000000000000002813 117.0
HFD1_k127_2045540_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 361.0
HFD1_k127_2045540_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 307.0
HFD1_k127_2045540_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001185 254.0
HFD1_k127_2045540_3 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000000000002069 217.0
HFD1_k127_2045540_4 - - - - 0.0000000000000000000000000001726 117.0
HFD1_k127_2045540_5 biopolymer transport protein - - - 0.00000000000000000000000001979 111.0
HFD1_k127_204807_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.71e-267 825.0
HFD1_k127_204807_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 3.445e-257 794.0
HFD1_k127_204807_10 Tetratricopeptide repeat - - - 0.0001143 54.0
HFD1_k127_204807_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 582.0
HFD1_k127_204807_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 414.0
HFD1_k127_204807_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003882 265.0
HFD1_k127_204807_5 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000000000000000000000000002916 182.0
HFD1_k127_204807_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000001976 150.0
HFD1_k127_204807_7 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000002954 134.0
HFD1_k127_204807_8 BolA family transcriptional regulator K09780 - - 0.0000000000000001046 83.0
HFD1_k127_204807_9 Tetratricopeptide repeat - - - 0.0000001828 63.0
HFD1_k127_2072870_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 334.0
HFD1_k127_2104590_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1532.0
HFD1_k127_2104590_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001663 274.0
HFD1_k127_2104590_10 Protein of unknown function (DUF1328) - - - 0.000000000000006193 77.0
HFD1_k127_2104590_11 Peptidase propeptide and YPEB domain - - - 0.000007015 52.0
HFD1_k127_2104590_12 Propeptide PepSY amd peptidase M4 - - - 0.0001307 48.0
HFD1_k127_2104590_2 Rubrerythrin K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001821 250.0
HFD1_k127_2104590_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000048 222.0
HFD1_k127_2104590_4 Protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000000000000000000003644 212.0
HFD1_k127_2104590_7 bacterial OsmY and nodulation domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.000000000000000001756 95.0
HFD1_k127_2104590_8 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000009174 87.0
HFD1_k127_2104590_9 CsbD-like - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000337 83.0
HFD1_k127_2146894_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 581.0
HFD1_k127_2146894_1 chlorophyll binding K03286,K16191 GO:0003674,GO:0005215,GO:0005488,GO:0005539,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0009268,GO:0009279,GO:0009628,GO:0010447,GO:0015267,GO:0015288,GO:0015696,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0034220,GO:0040007,GO:0042834,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044462,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071705,GO:0071944,GO:0072488,GO:0097367,GO:0098655 - 0.0000000000000000000002842 108.0
HFD1_k127_2149358_0 Elongation factor G C-terminus K06207 - - 0.0 1055.0
HFD1_k127_2149358_1 Hsp70 protein K04043,K04044 - - 0.0 1037.0
HFD1_k127_2149358_10 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004298 263.0
HFD1_k127_2149358_11 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000001462 264.0
HFD1_k127_2149358_13 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005168 250.0
HFD1_k127_2149358_14 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005406 244.0
HFD1_k127_2149358_15 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000004704 220.0
HFD1_k127_2149358_16 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000000000000000000000000000000000000000000000000000001162 216.0
HFD1_k127_2149358_17 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000005476 214.0
HFD1_k127_2149358_18 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000000000000000000000001977 207.0
HFD1_k127_2149358_19 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000000001423 198.0
HFD1_k127_2149358_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 7.345e-227 706.0
HFD1_k127_2149358_21 regulation of translation K03530 - - 0.00000000000000000000000000000000000000000008235 161.0
HFD1_k127_2149358_22 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000000000000000000000000000000000000003692 150.0
HFD1_k127_2149358_23 Iron-sulphur cluster assembly - - - 0.000000000000000000000000000000000005926 138.0
HFD1_k127_2149358_24 Domain of unknown function (DUF4440) - - - 0.0005772 48.0
HFD1_k127_2149358_3 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 1.827e-198 646.0
HFD1_k127_2149358_4 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 449.0
HFD1_k127_2149358_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 352.0
HFD1_k127_2149358_6 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 297.0
HFD1_k127_2149358_7 DnaJ molecular chaperone homology domain K04082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 298.0
HFD1_k127_2149358_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 286.0
HFD1_k127_2149358_9 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 281.0
HFD1_k127_2221933_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 3.843e-209 657.0
HFD1_k127_2221933_1 NeuB family K03856 - 2.5.1.54 5.1e-200 625.0
HFD1_k127_2221933_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 433.0
HFD1_k127_2221933_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 293.0
HFD1_k127_2221933_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000121 282.0
HFD1_k127_2221933_5 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000002217 150.0
HFD1_k127_227624_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1062.0
HFD1_k127_227624_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1043.0
HFD1_k127_227624_10 - - - - 0.000000000000000000000000000000000001148 141.0
HFD1_k127_227624_11 - - - - 0.0006693 43.0
HFD1_k127_227624_2 xylulokinase activity K00854 - 2.7.1.17 0.0 1036.0
HFD1_k127_227624_3 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 509.0
HFD1_k127_227624_4 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 477.0
HFD1_k127_227624_5 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 475.0
HFD1_k127_227624_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 329.0
HFD1_k127_227624_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 286.0
HFD1_k127_227624_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000006879 247.0
HFD1_k127_227624_9 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000001412 211.0
HFD1_k127_2320253_0 radical SAM domain protein - - - 0.0 1052.0
HFD1_k127_2320253_1 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 517.0
HFD1_k127_2320253_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 449.0
HFD1_k127_2328989_0 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 444.0
HFD1_k127_2328989_1 Sodium:sulfate symporter transmembrane region K03319,K09477,K11106,K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 330.0
HFD1_k127_2328989_2 PFAM IS1 transposase K07480 - - 0.000000000000000000000001163 108.0
HFD1_k127_2328989_3 Putative ATPase subunit of terminase (gpP-like) - - - 0.000000000000000000005591 99.0
HFD1_k127_2378066_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1436.0
HFD1_k127_2378066_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.92e-203 642.0
HFD1_k127_2378066_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 409.0
HFD1_k127_2378066_3 phosphonoacetaldehyde hydrolase activity K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 327.0
HFD1_k127_2378066_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 284.0
HFD1_k127_2378066_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000003695 119.0
HFD1_k127_2378066_8 response regulator - - - 0.000000000002017 76.0
HFD1_k127_2378066_9 Binds directly to 16S ribosomal RNA K02968 - - 0.00000007723 56.0
HFD1_k127_2403950_0 silver ion transport K15726 - - 0.0 1287.0
HFD1_k127_2403950_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798,K15727 - - 0.000000000000000000000000000000000006651 139.0
HFD1_k127_2419056_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 533.0
HFD1_k127_2419056_1 Protein of unknown function (DUF3443) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 323.0
HFD1_k127_2419056_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009239 230.0
HFD1_k127_2419056_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000003385 223.0
HFD1_k127_2419056_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000002304 209.0
HFD1_k127_2419056_6 Flavin reductase like domain - - - 0.000000000000000000000517 96.0
HFD1_k127_2419056_7 Protein of unknown function (DUF2844) - - - 0.0000000000000000000007944 104.0
HFD1_k127_2419056_8 - - - - 0.000000000000001438 83.0
HFD1_k127_2419056_9 Acetyltransferase (GNAT) domain - - - 0.00000000000002182 76.0
HFD1_k127_2420152_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1416.0
HFD1_k127_2420152_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.577e-298 919.0
HFD1_k127_2420152_2 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 410.0
HFD1_k127_2420152_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002186 267.0
HFD1_k127_2420152_5 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007657 264.0
HFD1_k127_2420152_6 Evidence 4 Homologs of previously reported genes of K15977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009771 253.0
HFD1_k127_2420152_7 protein disulfide oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004166 246.0
HFD1_k127_2420152_8 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000000000000000000000000002613 154.0
HFD1_k127_2420152_9 - - - - 0.00000000000000000000005779 100.0
HFD1_k127_2435623_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1433.0
HFD1_k127_2435623_1 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 447.0
HFD1_k127_2435623_10 PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000001608 179.0
HFD1_k127_2435623_11 transmembrane transport - - - 0.0000000000000000000000000000000000000000000009437 171.0
HFD1_k127_2435623_12 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000004684 163.0
HFD1_k127_2435623_13 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000001737 143.0
HFD1_k127_2435623_14 methyltransferase - - - 0.000000000000000000000001207 110.0
HFD1_k127_2435623_15 - - - - 0.0000000000000004259 78.0
HFD1_k127_2435623_16 - - - - 0.000000000000007503 74.0
HFD1_k127_2435623_2 NADP oxidoreductase coenzyme F420-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 327.0
HFD1_k127_2435623_3 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 315.0
HFD1_k127_2435623_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004112 269.0
HFD1_k127_2435623_5 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001872 252.0
HFD1_k127_2435623_6 PFAM regulatory protein TetR K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000006317 227.0
HFD1_k127_2435623_7 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000001475 185.0
HFD1_k127_2435623_8 Pyruvate kinase K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000531 183.0
HFD1_k127_2435623_9 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000008632 189.0
HFD1_k127_2437571_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 591.0
HFD1_k127_2438079_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1118.0
HFD1_k127_2438079_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1076.0
HFD1_k127_2438079_10 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 401.0
HFD1_k127_2438079_11 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 408.0
HFD1_k127_2438079_12 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 397.0
HFD1_k127_2438079_13 Cytochrome c K17052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 369.0
HFD1_k127_2438079_14 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 331.0
HFD1_k127_2438079_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
HFD1_k127_2438079_17 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001052 274.0
HFD1_k127_2438079_18 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000001656 236.0
HFD1_k127_2438079_19 adenosylhomocysteine nucleosidase activity K01243,K03527 - 1.17.7.4,3.2.2.9 0.0000000000000000000000000000000000000000000000000000000006402 211.0
HFD1_k127_2438079_2 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1051.0
HFD1_k127_2438079_21 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000002968 197.0
HFD1_k127_2438079_22 - - - - 0.0000000000000000000000000000000000000004263 152.0
HFD1_k127_2438079_3 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 6.023e-247 768.0
HFD1_k127_2438079_4 Cytochrome b/b6/petB K00412 - - 4.808e-230 713.0
HFD1_k127_2438079_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 3.017e-212 664.0
HFD1_k127_2438079_6 Surface antigen - - - 4.739e-207 649.0
HFD1_k127_2438079_7 Domain of unknown function (DUF3463) - - - 7.201e-207 646.0
HFD1_k127_2438079_8 oxidoreductase activity, acting on diphenols and related substances as donors K00240,K03886 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 527.0
HFD1_k127_2438079_9 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 419.0
HFD1_k127_2490946_0 cellulose binding - - - 0.0 1086.0
HFD1_k127_2493644_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1053.0
HFD1_k127_2493644_1 isomerase - - - 1.302e-250 797.0
HFD1_k127_2493644_10 COG0784 FOG CheY-like receiver - - - 0.0000000000008865 76.0
HFD1_k127_2493644_11 SMART Transport-associated and nodulation region K04065 - - 0.0000000002549 66.0
HFD1_k127_2493644_12 Helix-turn-helix domain - - - 0.00000006533 59.0
HFD1_k127_2493644_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 541.0
HFD1_k127_2493644_3 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 327.0
HFD1_k127_2493644_4 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000005586 203.0
HFD1_k127_2493644_5 peptidase K02557,K21471 - - 0.00000000000000000000000000000000000000000000000003831 196.0
HFD1_k127_2493644_6 - - - - 0.000000000000000000000000000000000000000000001214 170.0
HFD1_k127_2493644_7 peptidase K02557,K21471 - - 0.00000000000000000000000000000000005842 143.0
HFD1_k127_2493644_8 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000001585 92.0
HFD1_k127_2493644_9 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000002618 90.0
HFD1_k127_2496415_0 alanine dehydrogenase activity K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 544.0
HFD1_k127_2496415_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 411.0
HFD1_k127_2496415_2 - - - - 0.0000000000000000000000000000000000000000000000000000001091 197.0
HFD1_k127_2496415_3 - - - - 0.000000000000000000000000000000000000000000000000000007253 190.0
HFD1_k127_2496415_4 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000005503 184.0
HFD1_k127_2496415_5 - - - - 0.00000000000000000000000000000000000000000001033 168.0
HFD1_k127_2496415_6 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.00000000000000000005235 92.0
HFD1_k127_2506425_0 radical SAM domain protein - - - 2.42e-244 757.0
HFD1_k127_2506425_1 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 339.0
HFD1_k127_2506425_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000001131 171.0
HFD1_k127_2528424_0 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 358.0
HFD1_k127_2528424_1 methylisocitrate lyase activity K03417 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 353.0
HFD1_k127_2528424_2 Belongs to the citrate synthase family K01647,K01659 GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000006207 256.0
HFD1_k127_2529054_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1237.0
HFD1_k127_2529054_1 Evidence 4 Homologs of previously reported genes of - - - 3.931e-240 747.0
HFD1_k127_2529054_10 - - - - 0.00000000000000000000000000000000000000000000000000000000311 202.0
HFD1_k127_2529054_13 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000007351 162.0
HFD1_k127_2529054_15 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000002066 112.0
HFD1_k127_2529054_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 610.0
HFD1_k127_2529054_3 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 509.0
HFD1_k127_2529054_4 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 460.0
HFD1_k127_2529054_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 449.0
HFD1_k127_2529054_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 351.0
HFD1_k127_2529054_7 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 295.0
HFD1_k127_2529054_8 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 299.0
HFD1_k127_2529054_9 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007659 239.0
HFD1_k127_2532192_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1278.0
HFD1_k127_2532192_1 Heat shock 70 kDa protein K04043 - - 0.0 1142.0
HFD1_k127_2532192_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 351.0
HFD1_k127_2532192_11 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 336.0
HFD1_k127_2532192_12 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 328.0
HFD1_k127_2532192_13 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 304.0
HFD1_k127_2532192_14 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008679 276.0
HFD1_k127_2532192_15 drug transmembrane transporter activity K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006159 261.0
HFD1_k127_2532192_16 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000000000000268 228.0
HFD1_k127_2532192_17 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000002627 222.0
HFD1_k127_2532192_18 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000005407 207.0
HFD1_k127_2532192_19 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000005995 211.0
HFD1_k127_2532192_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 2.786e-237 741.0
HFD1_k127_2532192_20 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000221 143.0
HFD1_k127_2532192_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.076e-232 728.0
HFD1_k127_2532192_4 guanyl-nucleotide exchange factor activity - - - 9.246e-225 711.0
HFD1_k127_2532192_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 426.0
HFD1_k127_2532192_6 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 417.0
HFD1_k127_2532192_7 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 411.0
HFD1_k127_2532192_8 Belongs to the sirtuin family. Class K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 377.0
HFD1_k127_2532192_9 phosphopentomutase activity K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 364.0
HFD1_k127_2549033_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 3.832e-312 965.0
HFD1_k127_2549033_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.456e-282 873.0
HFD1_k127_2549033_10 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 341.0
HFD1_k127_2549033_11 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 307.0
HFD1_k127_2549033_12 RDD family - - - 0.000000000000000000000000000000000000000000000000000000005626 202.0
HFD1_k127_2549033_13 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000001987 192.0
HFD1_k127_2549033_14 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000001059 160.0
HFD1_k127_2549033_16 Protein of unknown function (DUF2905) - - - 0.0000000000000000007642 90.0
HFD1_k127_2549033_17 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000001667 73.0
HFD1_k127_2549033_2 Actin K03569 - - 4.928e-205 640.0
HFD1_k127_2549033_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 1.851e-195 619.0
HFD1_k127_2549033_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 605.0
HFD1_k127_2549033_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 560.0
HFD1_k127_2549033_6 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 467.0
HFD1_k127_2549033_7 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 456.0
HFD1_k127_2549033_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 392.0
HFD1_k127_2549033_9 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 362.0
HFD1_k127_2564088_0 nodulation K00612 - - 1.826e-245 771.0
HFD1_k127_2564088_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 6.728e-241 748.0
HFD1_k127_2564088_10 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 287.0
HFD1_k127_2564088_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 281.0
HFD1_k127_2564088_12 Mo-molybdopterin cofactor metabolic process K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000005933 263.0
HFD1_k127_2564088_2 Trypsin K04771 - 3.4.21.107 7.168e-241 756.0
HFD1_k127_2564088_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 9.62e-197 614.0
HFD1_k127_2564088_4 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 533.0
HFD1_k127_2564088_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 512.0
HFD1_k127_2564088_6 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 510.0
HFD1_k127_2564088_7 macromolecule localization K01421,K01992,K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 415.0
HFD1_k127_2564088_8 denitrification pathway K02569,K03532,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 393.0
HFD1_k127_2564088_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 379.0
HFD1_k127_257115_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 544.0
HFD1_k127_257115_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 512.0
HFD1_k127_257115_2 FtsZ-dependent cytokinesis K09892,K13924 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044424,GO:0044444,GO:0044464,GO:0051301 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 292.0
HFD1_k127_257115_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005626 231.0
HFD1_k127_257115_4 Membrane - - - 0.000000000000000000000000000000000000000000000003473 176.0
HFD1_k127_257115_5 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000005287 145.0
HFD1_k127_257115_6 integral membrane protein - - - 0.000000000000000000000000000000002686 134.0
HFD1_k127_259301_0 Pup-ligase protein K20814 - 3.5.1.119 1.402e-273 848.0
HFD1_k127_259301_1 Proteasomal ATPase OB/ID domain K13527 - - 1.525e-271 848.0
HFD1_k127_259301_10 hmm pf02371 K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 342.0
HFD1_k127_259301_11 Proteasome subunit K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 339.0
HFD1_k127_259301_12 Evidence 5 No homology to any previously reported sequences K02450,K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 323.0
HFD1_k127_259301_13 chlorophyll binding K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 239.0
HFD1_k127_259301_14 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000000000001556 229.0
HFD1_k127_259301_16 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000008844 204.0
HFD1_k127_259301_17 bis(5'-adenosyl)-triphosphatase activity - - - 0.00000000000000000000000000000000000000000000000002064 184.0
HFD1_k127_259301_18 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000001596 173.0
HFD1_k127_259301_19 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000007043 162.0
HFD1_k127_259301_2 Pup-ligase protein K13571 - 6.3.1.19 1.86e-251 782.0
HFD1_k127_259301_20 acetyltransferase - - - 0.0000000000000000000000000000000000000004356 158.0
HFD1_k127_259301_21 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000000000000007527 118.0
HFD1_k127_259301_22 May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes - - - 0.0000000000000000000000003802 106.0
HFD1_k127_259301_23 serine threonine protein kinase - - - 0.000000000000000000001468 100.0
HFD1_k127_259301_3 Chase2 domain K01768,K07315 - 3.1.3.3,4.6.1.1 7.124e-245 784.0
HFD1_k127_259301_4 oxidoreductase activity K07114 - - 1.507e-244 775.0
HFD1_k127_259301_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 516.0
HFD1_k127_259301_6 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 437.0
HFD1_k127_259301_7 Proteasome subunit K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 428.0
HFD1_k127_259301_8 poly(3-hydroxybutyrate) depolymerase activity K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 425.0
HFD1_k127_259301_9 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 415.0
HFD1_k127_262689_0 ResB-like family K07399 - - 8.605e-257 800.0
HFD1_k127_262689_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.231e-243 756.0
HFD1_k127_262689_10 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 340.0
HFD1_k127_262689_11 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 306.0
HFD1_k127_262689_12 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 295.0
HFD1_k127_262689_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000003537 218.0
HFD1_k127_262689_14 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000007406 213.0
HFD1_k127_262689_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 8.463e-230 713.0
HFD1_k127_262689_3 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 1.39e-203 645.0
HFD1_k127_262689_4 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 589.0
HFD1_k127_262689_5 heme binding K00463 - 1.13.11.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 574.0
HFD1_k127_262689_6 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 523.0
HFD1_k127_262689_7 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 417.0
HFD1_k127_262689_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 409.0
HFD1_k127_262689_9 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 340.0
HFD1_k127_2636782_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1554.0
HFD1_k127_2636782_1 phosphorelay signal transduction system - - - 5.627e-209 660.0
HFD1_k127_2636782_2 - - - - 7.338e-207 644.0
HFD1_k127_2636782_3 anaphase-promoting complex binding - - - 3.143e-197 619.0
HFD1_k127_2636782_4 protein complex oligomerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 540.0
HFD1_k127_2636782_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 501.0
HFD1_k127_2636782_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 481.0
HFD1_k127_2636782_7 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 295.0
HFD1_k127_2636782_8 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000000000000000000000000003905 179.0
HFD1_k127_2644073_0 Glycosyl hydrolase family 57 - - - 0.0 1045.0
HFD1_k127_2644073_1 Proton-conducting membrane transporter K12137 - - 9.031e-312 967.0
HFD1_k127_2644073_11 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000002703 76.0
HFD1_k127_2644073_12 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00001153 49.0
HFD1_k127_2644073_2 protein secretion by the type I secretion system K02021 - - 7.648e-252 787.0
HFD1_k127_2644073_3 phosphorelay signal transduction system K02481 - - 7.624e-244 758.0
HFD1_k127_2644073_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 587.0
HFD1_k127_2644073_5 phosphorelay sensor kinase activity K02668,K10942 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 565.0
HFD1_k127_2644073_6 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 535.0
HFD1_k127_2644073_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 290.0
HFD1_k127_2644073_8 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003416 257.0
HFD1_k127_2644073_9 - - - - 0.000000000000000000000000009484 114.0
HFD1_k127_2646849_0 Aminotransferase class I and II K10206 - 2.6.1.83 6.187e-248 766.0
HFD1_k127_2646849_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 459.0
HFD1_k127_2646849_11 PFAM Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000004503 157.0
HFD1_k127_2646849_12 - - - - 0.00000000000000000000000000000001085 129.0
HFD1_k127_2646849_14 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000006674 57.0
HFD1_k127_2646849_2 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 463.0
HFD1_k127_2646849_3 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 332.0
HFD1_k127_2646849_4 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 297.0
HFD1_k127_2646849_6 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002211 265.0
HFD1_k127_2646849_7 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 259.0
HFD1_k127_2646849_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005717 241.0
HFD1_k127_2663371_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1443.0
HFD1_k127_2663371_1 succinyl-diaminopimelate desuccinylase activity - - - 2.848e-244 760.0
HFD1_k127_2663371_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004554 272.0
HFD1_k127_2663371_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00406,K12263 - - 0.000000000000000000000000000000007607 135.0
HFD1_k127_2663371_15 AntiSigma factor - - - 0.00000000000000000000007083 101.0
HFD1_k127_2663371_16 response regulator - - - 0.000000000279 72.0
HFD1_k127_2663371_17 rRNA binding K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000001232 54.0
HFD1_k127_2663371_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.109e-216 680.0
HFD1_k127_2663371_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 402.0
HFD1_k127_2663371_5 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 383.0
HFD1_k127_2663371_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 336.0
HFD1_k127_2663371_7 phosphonoacetaldehyde hydrolase activity K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 325.0
HFD1_k127_2663371_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 293.0
HFD1_k127_2663371_9 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
HFD1_k127_271441_0 amine dehydrogenase activity - - - 0.0 1755.0
HFD1_k127_271441_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1227.0
HFD1_k127_271441_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 424.0
HFD1_k127_271441_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 419.0
HFD1_k127_271441_12 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 407.0
HFD1_k127_271441_13 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 378.0
HFD1_k127_271441_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 358.0
HFD1_k127_271441_15 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 320.0
HFD1_k127_271441_16 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 326.0
HFD1_k127_271441_17 peroxidase activity K09162 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114 1.13.11.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 321.0
HFD1_k127_271441_18 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 305.0
HFD1_k127_271441_19 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 276.0
HFD1_k127_271441_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 9.7e-322 1006.0
HFD1_k127_271441_20 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008228 269.0
HFD1_k127_271441_21 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000006911 234.0
HFD1_k127_271441_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003332 232.0
HFD1_k127_271441_23 protein homooligomerization - - - 0.0000000000000000000000000000000000000000000000000000000000000001192 234.0
HFD1_k127_271441_24 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000004151 224.0
HFD1_k127_271441_25 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000001455 209.0
HFD1_k127_271441_28 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000006105 183.0
HFD1_k127_271441_29 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.000000000000000000000000000000000000002021 147.0
HFD1_k127_271441_3 methyltransferase - - - 2.97e-277 857.0
HFD1_k127_271441_30 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000001046 139.0
HFD1_k127_271441_38 Protein of unknown function, DUF393 - - - 0.000124 51.0
HFD1_k127_271441_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.691e-265 822.0
HFD1_k127_271441_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.78e-232 724.0
HFD1_k127_271441_6 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.523e-225 701.0
HFD1_k127_271441_7 photosynthesis K02453,K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 533.0
HFD1_k127_271441_8 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 501.0
HFD1_k127_271441_9 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 442.0
HFD1_k127_2720550_0 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 356.0
HFD1_k127_2720550_1 precorrin-2 dehydrogenase activity K02302,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 335.0
HFD1_k127_2720550_2 - K19246 - 1.13.11.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 346.0
HFD1_k127_2720550_3 cytochrome complex assembly K02200,K04018,K19225,K20543,K21007 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000001241 218.0
HFD1_k127_2720550_4 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000000000007351 169.0
HFD1_k127_2720550_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000000000002061 130.0
HFD1_k127_2739410_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 484.0
HFD1_k127_2739410_1 NTPase - - - 0.000000000000000000000000000000000000000000002716 172.0
HFD1_k127_2739410_2 Glyoxalase-like domain - - - 0.0000000000000000000000000002069 119.0
HFD1_k127_2739410_3 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000006714 64.0
HFD1_k127_2788173_0 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 553.0
HFD1_k127_2788173_1 PFAM transposase IS3 IS911 family protein - - - 0.0000000000000000000000000000000000000000000000000000003755 194.0
HFD1_k127_2788173_2 Integrase core domain K07497 - - 0.00000000000000000000001333 105.0
HFD1_k127_2788173_3 - - - - 0.00000000000006636 84.0
HFD1_k127_2788173_4 Peptidase family M28 - - - 0.000000000003527 70.0
HFD1_k127_2803825_0 paraquat-inducible protein b K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 360.0
HFD1_k127_2803825_1 Paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001039 248.0
HFD1_k127_2804266_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1548.0
HFD1_k127_2804266_1 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1256.0
HFD1_k127_2804266_10 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 511.0
HFD1_k127_2804266_11 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 466.0
HFD1_k127_2804266_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 353.0
HFD1_k127_2804266_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 341.0
HFD1_k127_2804266_14 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 324.0
HFD1_k127_2804266_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 308.0
HFD1_k127_2804266_16 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 311.0
HFD1_k127_2804266_17 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 343.0
HFD1_k127_2804266_18 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 301.0
HFD1_k127_2804266_19 Uncharacterized protein family, UPF0114 K03535 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 292.0
HFD1_k127_2804266_2 NADH-quinone oxidoreductase K00341 - 1.6.5.3 0.0 1011.0
HFD1_k127_2804266_20 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001071 257.0
HFD1_k127_2804266_21 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000001514 222.0
HFD1_k127_2804266_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000002717 228.0
HFD1_k127_2804266_23 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001352 216.0
HFD1_k127_2804266_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001926 204.0
HFD1_k127_2804266_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000001735 161.0
HFD1_k127_2804266_26 DGC domain - - - 0.00000000000000000000000000000000000000006724 157.0
HFD1_k127_2804266_27 - - - - 0.000000000000000000000000000000002147 131.0
HFD1_k127_2804266_28 Acetyltransferase (GNAT) domain - - - 0.000000000000000000002084 100.0
HFD1_k127_2804266_29 cheY-homologous receiver domain - - - 0.0000000000003229 77.0
HFD1_k127_2804266_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 7.555e-299 925.0
HFD1_k127_2804266_30 Short C-terminal domain K08982 - - 0.0000000001335 64.0
HFD1_k127_2804266_33 phosphorelay sensor kinase activity K16923 - - 0.0000001088 64.0
HFD1_k127_2804266_35 Patatin-like phospholipase - - - 0.0002017 51.0
HFD1_k127_2804266_4 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 2.689e-259 802.0
HFD1_k127_2804266_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 4.959e-234 733.0
HFD1_k127_2804266_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 8.938e-211 671.0
HFD1_k127_2804266_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 4.276e-202 632.0
HFD1_k127_2804266_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 591.0
HFD1_k127_2804266_9 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 524.0
HFD1_k127_2806160_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 7.505e-278 883.0
HFD1_k127_2806160_1 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 524.0
HFD1_k127_2806160_2 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 452.0
HFD1_k127_2806160_3 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 385.0
HFD1_k127_2806160_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 379.0
HFD1_k127_2806160_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000001741 200.0
HFD1_k127_2806160_7 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.00000000000000000001475 94.0
HFD1_k127_2844545_0 Dehydratase family K01687 - 4.2.1.9 2.564e-321 992.0
HFD1_k127_2844545_1 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 8.696e-210 663.0
HFD1_k127_2844545_10 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000007848 209.0
HFD1_k127_2844545_11 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000006526 196.0
HFD1_k127_2844545_12 peptidase - - - 0.00000000000000000000000000000000005821 137.0
HFD1_k127_2844545_13 thiamine diphosphate biosynthetic process K03154 - - 0.00000000000000000000000005115 109.0
HFD1_k127_2844545_14 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.00000000000000000000002519 115.0
HFD1_k127_2844545_15 self proteolysis - - - 0.00000000000000000007476 100.0
HFD1_k127_2844545_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000006428 68.0
HFD1_k127_2844545_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 574.0
HFD1_k127_2844545_3 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 495.0
HFD1_k127_2844545_4 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 479.0
HFD1_k127_2844545_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 440.0
HFD1_k127_2844545_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 413.0
HFD1_k127_2844545_7 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002624 273.0
HFD1_k127_2844545_8 transferase activity, transferring glycosyl groups K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003404 273.0
HFD1_k127_2844545_9 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000006079 235.0
HFD1_k127_285712_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.652e-305 946.0
HFD1_k127_285712_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 387.0
HFD1_k127_285712_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000001199 133.0
HFD1_k127_2858389_0 molybdopterin cofactor binding K00370,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4 0.0 2305.0
HFD1_k127_2858389_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 323.0
HFD1_k127_2858389_2 signal transduction histidine kinase - - - 0.000000000000000000000000000000000006944 156.0
HFD1_k127_2902142_0 Protein of unknown function, DUF255 K06888 - - 0.0 1627.0
HFD1_k127_2902142_1 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 292.0
HFD1_k127_2902142_2 transposase activity K07483,K07497 - - 0.00000000000000000000000000000000000000000002943 163.0
HFD1_k127_2902142_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 0.00001926 51.0
HFD1_k127_2937987_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.698e-272 852.0
HFD1_k127_2937987_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.066e-246 764.0
HFD1_k127_2937987_10 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.000009517 57.0
HFD1_k127_2937987_2 Histidine kinase K00060,K07777 - 1.1.1.103,2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 565.0
HFD1_k127_2937987_4 NADPH:quinone reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 318.0
HFD1_k127_2937987_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000006745 233.0
HFD1_k127_2937987_6 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001524 229.0
HFD1_k127_2937987_7 Response regulator receiver K02479 - - 0.000000000000000000000000000000000000000000000000000000000001896 216.0
HFD1_k127_2937987_8 phosphorelay signal transduction system K02535 - 3.5.1.108 0.000000000000000000000000002791 115.0
HFD1_k127_2940572_0 Histidine kinase K07638 - 2.7.13.3 5.074e-321 1007.0
HFD1_k127_2940572_1 Histidine kinase K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 434.0
HFD1_k127_2940572_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002462 243.0
HFD1_k127_2940572_3 Histidine kinase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000005796 239.0
HFD1_k127_2965679_0 cobalamin-transporting ATPase activity K02014,K16092 - - 3.86e-239 757.0
HFD1_k127_2965679_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 391.0
HFD1_k127_2965679_2 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 372.0
HFD1_k127_2965679_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 355.0
HFD1_k127_2965679_4 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 313.0
HFD1_k127_2965679_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000001076 204.0
HFD1_k127_2965679_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000003117 105.0
HFD1_k127_2965679_7 Alternative locus ID K15383 - - 0.00000000005706 64.0
HFD1_k127_2965679_9 PQ loop repeat K15383 - - 0.0001086 45.0
HFD1_k127_300343_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 390.0
HFD1_k127_300343_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 342.0
HFD1_k127_300343_2 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006055 283.0
HFD1_k127_300343_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000002334 226.0
HFD1_k127_300343_4 Bacterial PH domain - - - 0.000000000000000000000000000001307 124.0
HFD1_k127_3033017_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1055.0
HFD1_k127_3033017_1 Translation initiation factor IF-3, C-terminal domain K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 300.0
HFD1_k127_3033017_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000005376 203.0
HFD1_k127_3033017_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000009743 61.0
HFD1_k127_3038720_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.644e-254 786.0
HFD1_k127_3038720_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.656e-205 645.0
HFD1_k127_3038720_10 Belongs to the ompA family - - - 0.00002396 53.0
HFD1_k127_3038720_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 606.0
HFD1_k127_3038720_3 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 453.0
HFD1_k127_3038720_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 393.0
HFD1_k127_3038720_5 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005811 246.0
HFD1_k127_3038720_6 peptidase K02557,K21471 - - 0.0000000000000000000000000000000000000000000000000000001857 211.0
HFD1_k127_3038720_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000182 187.0
HFD1_k127_3038720_8 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000007397 166.0
HFD1_k127_3038720_9 CGNR zinc finger - - - 0.0000000000000000000000000000004992 130.0
HFD1_k127_3095366_0 Type II/IV secretion system protein K02454,K02652 - - 7.198e-234 738.0
HFD1_k127_3095366_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 539.0
HFD1_k127_3095366_2 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 401.0
HFD1_k127_3095366_3 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000002597 240.0
HFD1_k127_3095366_4 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000001008 175.0
HFD1_k127_3095366_6 Transglycosylase SLT domain - - - 0.00000000000000000000000000001201 124.0
HFD1_k127_3133891_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 417.0
HFD1_k127_3133891_1 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 311.0
HFD1_k127_3133891_2 antisigma factor binding K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 301.0
HFD1_k127_3133891_3 energy transducer activity K03407,K03832 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000008107 228.0
HFD1_k127_3189704_0 Evidence 5 No homology to any previously reported sequences K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 519.0
HFD1_k127_3189704_1 Cytochrome c K02305,K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 482.0
HFD1_k127_3189704_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 306.0
HFD1_k127_3189704_3 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001693 279.0
HFD1_k127_3189704_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001202 275.0
HFD1_k127_3190318_0 AAA domain - - - 5.587e-318 982.0
HFD1_k127_3190318_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 536.0
HFD1_k127_3190318_2 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 370.0
HFD1_k127_3190318_3 thiolester hydrolase activity K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 291.0
HFD1_k127_3190318_4 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000001194 248.0
HFD1_k127_3190318_5 regulation of translation K03704,K05809 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007078 249.0
HFD1_k127_3190318_6 Universal stress protein family - - - 0.00000000000006437 78.0
HFD1_k127_3193334_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 8.299e-214 670.0
HFD1_k127_3193334_1 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 493.0
HFD1_k127_3193334_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 480.0
HFD1_k127_3193334_3 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 417.0
HFD1_k127_3193334_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K05553 - - 0.000000000000000000000000000001373 124.0
HFD1_k127_3221597_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 1532.0
HFD1_k127_3245155_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.012e-314 965.0
HFD1_k127_3245155_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.219e-197 617.0
HFD1_k127_3246569_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.943e-266 826.0
HFD1_k127_3246569_1 nitric oxide dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001315 233.0
HFD1_k127_3246569_2 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000006295 130.0
HFD1_k127_3276308_1 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000085 93.0
HFD1_k127_32822_0 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 308.0
HFD1_k127_32822_1 - - - - 0.000000000000000000000000000000000000000000000000000000001213 203.0
HFD1_k127_32822_2 - - - - 0.000000000000000001691 91.0
HFD1_k127_32822_3 - - - - 0.0000000003617 65.0
HFD1_k127_32822_5 RibD C-terminal domain - - - 0.0005401 43.0
HFD1_k127_3291560_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1517.0
HFD1_k127_3291560_1 Beta-Casp domain K07576 - - 5.708e-246 766.0
HFD1_k127_3291560_11 G/U mismatch-specific uracil-DNA glycosylase activity K01934,K03649 GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.28,6.3.3.2 0.000000000000000000000000000000000000000000000000000281 190.0
HFD1_k127_3291560_12 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005278 187.0
HFD1_k127_3291560_13 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000001769 186.0
HFD1_k127_3291560_14 RF-1 domain K15034 - - 0.000000000000000000000000000000000000000000000000002432 184.0
HFD1_k127_3291560_15 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000001433 136.0
HFD1_k127_3291560_16 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000000000000002466 137.0
HFD1_k127_3291560_2 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 567.0
HFD1_k127_3291560_21 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 0.000000000000000000006033 91.0
HFD1_k127_3291560_22 - - - - 0.000000000001081 72.0
HFD1_k127_3291560_3 Aminomethyltransferase folate-binding domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 494.0
HFD1_k127_3291560_4 FIST C domain - GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 466.0
HFD1_k127_3291560_5 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 449.0
HFD1_k127_3291560_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 395.0
HFD1_k127_3291560_7 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005961 269.0
HFD1_k127_3291560_8 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000005598 231.0
HFD1_k127_3304534_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 475.0
HFD1_k127_3304534_1 Sugar (and other) transporter K05548,K08369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 464.0
HFD1_k127_3304534_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000001728 211.0
HFD1_k127_3304534_3 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000008119 187.0
HFD1_k127_3304534_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000001221 180.0
HFD1_k127_3304534_5 Phospholipase, patatin family - - - 0.0002452 53.0
HFD1_k127_3323992_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 429.0
HFD1_k127_3323992_1 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 380.0
HFD1_k127_3323992_11 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000001678 106.0
HFD1_k127_3323992_13 - - - - 0.0005154 49.0
HFD1_k127_3323992_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 380.0
HFD1_k127_3323992_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 374.0
HFD1_k127_3323992_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 321.0
HFD1_k127_3323992_6 thiolester hydrolase activity K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 316.0
HFD1_k127_3323992_7 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001275 285.0
HFD1_k127_3323992_8 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
HFD1_k127_3323992_9 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000003552 222.0
HFD1_k127_3345019_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00167,K11381,K21417 - 1.2.4.4 1.122e-197 617.0
HFD1_k127_3345019_1 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 606.0
HFD1_k127_3345019_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 578.0
HFD1_k127_3345019_3 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 560.0
HFD1_k127_3345019_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 534.0
HFD1_k127_3345019_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 495.0
HFD1_k127_3345019_6 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 345.0
HFD1_k127_3345019_7 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 305.0
HFD1_k127_3345019_8 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001745 281.0
HFD1_k127_3345019_9 S-acyltransferase activity K00658,K09699 - 2.3.1.168,2.3.1.61 0.00000000000000000000000000000000000000002163 155.0
HFD1_k127_3349128_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.679e-314 977.0
HFD1_k127_3349128_1 Nitroreductase - - - 8.744e-291 901.0
HFD1_k127_3349128_11 Outer membrane protease K01355,K08477,K08566,K13520 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009279,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0043170,GO:0044238,GO:0044425,GO:0044462,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.23.48,3.4.23.49 0.00000000000000000000000000000000000000000000000000000000000000002028 236.0
HFD1_k127_3349128_12 Peptidase M15 K02395 - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
HFD1_k127_3349128_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000003145 206.0
HFD1_k127_3349128_14 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000001865 186.0
HFD1_k127_3349128_15 phosphorelay signal transduction system K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000005722 183.0
HFD1_k127_3349128_16 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000009168 182.0
HFD1_k127_3349128_17 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000006826 166.0
HFD1_k127_3349128_18 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.00000000000000000000000000000000004533 145.0
HFD1_k127_3349128_2 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 614.0
HFD1_k127_3349128_20 cellulase activity K18197 - 4.2.2.23 0.00000000000000000000002165 113.0
HFD1_k127_3349128_4 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 437.0
HFD1_k127_3349128_5 transferase activity, transferring hexosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 394.0
HFD1_k127_3349128_6 Anti-sigma-K factor rskA K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 365.0
HFD1_k127_3349128_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 332.0
HFD1_k127_3349128_8 drug transmembrane transporter activity K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000189 256.0
HFD1_k127_3349128_9 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007945 253.0
HFD1_k127_3350970_0 Protein of unknown function, DUF255 K06888 - - 0.0 1527.0
HFD1_k127_3350970_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 8.533e-241 751.0
HFD1_k127_3350970_10 diguanylate cyclase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000004669 150.0
HFD1_k127_3350970_11 peptidyl-tyrosine sulfation K02450 - - 0.0000000000000000000000000008109 119.0
HFD1_k127_3350970_13 General secretion pathway protein C K02452 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0004649 49.0
HFD1_k127_3350970_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 571.0
HFD1_k127_3350970_3 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 520.0
HFD1_k127_3350970_4 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 521.0
HFD1_k127_3350970_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 460.0
HFD1_k127_3350970_6 heat shock protein binding K05516,K05801,K18481 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002911 274.0
HFD1_k127_3350970_8 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000006241 175.0
HFD1_k127_3374759_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 478.0
HFD1_k127_3374759_1 response regulator receiver K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 475.0
HFD1_k127_3374759_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 347.0
HFD1_k127_3374759_3 undecaprenyl-phosphate glucose phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 310.0
HFD1_k127_3374759_4 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 307.0
HFD1_k127_3374759_5 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000283 267.0
HFD1_k127_3374759_6 eight transmembrane protein EpsH - - - 0.0000000000000000000000000000003568 136.0
HFD1_k127_3374759_7 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000158 96.0
HFD1_k127_3426321_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 9.496e-249 771.0
HFD1_k127_3426321_1 Pfam:DUF989 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 304.0
HFD1_k127_3426321_2 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.0000000000000000000000000000000000000000000000000004853 185.0
HFD1_k127_3426321_3 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000229 91.0
HFD1_k127_3436011_0 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006066 259.0
HFD1_k127_3436011_1 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000004997 212.0
HFD1_k127_3436011_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000005975 151.0
HFD1_k127_344363_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 6.959e-209 662.0
HFD1_k127_344363_1 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 295.0
HFD1_k127_344363_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000005107 260.0
HFD1_k127_344363_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000000000000000000876 196.0
HFD1_k127_344363_5 cheY-homologous receiver domain - - - 0.0000000007886 59.0
HFD1_k127_3471407_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1701.0
HFD1_k127_3471407_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 561.0
HFD1_k127_3471407_10 SprT-like family K02742 - - 0.0000000000000000000000000000000000000000000000000000000000003402 217.0
HFD1_k127_3471407_11 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000008548 177.0
HFD1_k127_3471407_12 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000000000000000000000000000001104 179.0
HFD1_k127_3471407_13 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000002845 181.0
HFD1_k127_3471407_14 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000001056 183.0
HFD1_k127_3471407_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 499.0
HFD1_k127_3471407_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 485.0
HFD1_k127_3471407_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 472.0
HFD1_k127_3471407_5 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 370.0
HFD1_k127_3471407_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 311.0
HFD1_k127_3471407_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 302.0
HFD1_k127_3471407_8 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 313.0
HFD1_k127_3471407_9 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000000000000002639 236.0
HFD1_k127_3479675_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000009031 184.0
HFD1_k127_3479675_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000002598 157.0
HFD1_k127_3479675_2 SnoaL-like polyketide cyclase - - - 0.0000008322 52.0
HFD1_k127_3485027_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 586.0
HFD1_k127_3485027_1 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 513.0
HFD1_k127_3485027_2 self proteolysis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004432 264.0
HFD1_k127_3485027_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000002165 154.0
HFD1_k127_3485027_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000002143 89.0
HFD1_k127_3502879_0 AcrB/AcrD/AcrF family - - - 0.0 1119.0
HFD1_k127_3502879_1 Histidine kinase - - - 2.723e-310 960.0
HFD1_k127_3502879_10 serine-type endopeptidase activity K08372 - - 0.00000000000000000000000000000000000000000000000000000000008759 218.0
HFD1_k127_3502879_11 transmembrane signaling receptor activity - - - 0.0000000000000000000000000000000000000001211 156.0
HFD1_k127_3502879_12 histidine kinase, HAMP - - - 0.0000000000000000000000000000000000000002102 168.0
HFD1_k127_3502879_13 PFAM Phosphate-selective porin O K07221 - - 0.00000000000000000000000000639 126.0
HFD1_k127_3502879_14 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000008004 118.0
HFD1_k127_3502879_15 phosphorelay signal transduction system - - - 0.0000000000000000006966 91.0
HFD1_k127_3502879_16 outer membrane efflux protein - - - 0.00000000000007698 84.0
HFD1_k127_3502879_2 phosphoserine phosphatase activity K02668,K07710,K07711,K10942 - 2.7.13.3 3.278e-210 671.0
HFD1_k127_3502879_3 phosphorelay signal transduction system - - - 1.643e-202 639.0
HFD1_k127_3502879_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 477.0
HFD1_k127_3502879_5 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 415.0
HFD1_k127_3502879_6 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 359.0
HFD1_k127_3502879_7 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 302.0
HFD1_k127_3502879_8 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004203 258.0
HFD1_k127_3502879_9 Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000000000000000008339 239.0
HFD1_k127_3556294_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.73e-225 704.0
HFD1_k127_3556294_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 1.808e-210 664.0
HFD1_k127_3556294_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 490.0
HFD1_k127_3556294_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 451.0
HFD1_k127_3556294_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 421.0
HFD1_k127_3660514_0 DNA-directed DNA polymerase activity K02347,K04477 - - 4.608e-257 806.0
HFD1_k127_3660514_1 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 578.0
HFD1_k127_3660514_10 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000005713 147.0
HFD1_k127_3660514_11 Universal stress protein - - - 0.0000000000000000000000000000000000002858 151.0
HFD1_k127_3660514_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000005075 139.0
HFD1_k127_3660514_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 370.0
HFD1_k127_3660514_3 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 314.0
HFD1_k127_3660514_4 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008633 263.0
HFD1_k127_3660514_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000002197 236.0
HFD1_k127_3660514_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002163 227.0
HFD1_k127_3660514_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.0000000000000000000000000000000000000000000000004466 177.0
HFD1_k127_3660514_8 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000003099 192.0
HFD1_k127_3701865_1 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 349.0
HFD1_k127_3701865_2 fructose-bisphosphate aldolase activity K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 322.0
HFD1_k127_3701865_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 0.0000000000000000000000000000000000000000001374 158.0
HFD1_k127_3701865_4 CHASE3 domain - - - 0.0006514 49.0
HFD1_k127_3708612_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 2.992e-227 712.0
HFD1_k127_3708612_1 coenzyme binding K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 427.0
HFD1_k127_3708612_2 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
HFD1_k127_3708612_3 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 286.0
HFD1_k127_3708612_4 - - - - 0.0000000000000000000000000000000000000000000000000000000003085 210.0
HFD1_k127_3708612_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000001354 156.0
HFD1_k127_3719335_0 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 501.0
HFD1_k127_3719335_1 rRNA (guanine-N2-)-methyltransferase activity K09846,K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.210,2.1.1.304,2.1.1.333 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 493.0
HFD1_k127_3719335_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 455.0
HFD1_k127_3719335_3 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 412.0
HFD1_k127_3719335_4 membrane K08976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 336.0
HFD1_k127_3719335_7 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002858 203.0
HFD1_k127_3728939_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.306e-317 981.0
HFD1_k127_3728939_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 1.215e-209 654.0
HFD1_k127_3728939_2 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 493.0
HFD1_k127_3728939_3 photosynthesis - - - 0.0000000000000000000000000002632 114.0
HFD1_k127_3828595_0 Protein of unknown function (DUF3604) - - - 2.89e-321 993.0
HFD1_k127_3828595_1 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 477.0
HFD1_k127_3828595_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001576 261.0
HFD1_k127_3828595_3 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001194 261.0
HFD1_k127_3828595_4 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000001681 186.0
HFD1_k127_3828595_5 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000005043 187.0
HFD1_k127_3828595_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000008848 172.0
HFD1_k127_3828595_7 COG0625 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000003741 125.0
HFD1_k127_3859199_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 315.0
HFD1_k127_3859199_1 Biotin-lipoyl like K01993,K16922 - - 0.00000001019 63.0
HFD1_k127_3871333_0 PFAM Integrase, catalytic core K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 487.0
HFD1_k127_3871333_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 479.0
HFD1_k127_3871333_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000004264 240.0
HFD1_k127_3871333_3 RelA SpoT - - - 0.0000000000000000000000000000000000000000000000003055 188.0
HFD1_k127_3871333_4 PFAM Transposase IS3 IS911 K07483 - - 0.0000000000000000000000000000000001095 136.0
HFD1_k127_3871333_6 histidine kinase A domain protein - - - 0.000002326 51.0
HFD1_k127_3873040_0 Domain of unknown function (DUF4105) - - - 9.767e-315 975.0
HFD1_k127_3873040_1 alcohol dehydrogenase K00060,K07777 - 1.1.1.103,2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 601.0
HFD1_k127_3873040_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 603.0
HFD1_k127_3873040_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 477.0
HFD1_k127_3873040_4 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 382.0
HFD1_k127_3873040_5 Lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 333.0
HFD1_k127_3873040_6 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008539 266.0
HFD1_k127_3873040_7 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000002166 124.0
HFD1_k127_3873040_8 Domain of unknown function (DUF3332) - - - 0.000000000000000007805 91.0
HFD1_k127_3885419_0 Competence protein K02238 - - 1.055e-217 703.0
HFD1_k127_3885419_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 1.206e-206 650.0
HFD1_k127_3885419_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 572.0
HFD1_k127_3885419_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000003697 248.0
HFD1_k127_3885419_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000004681 229.0
HFD1_k127_389517_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 327.0
HFD1_k127_389517_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000001253 224.0
HFD1_k127_389517_2 DNA integration - - - 0.0000000000000000000000000000000000000000000000002389 184.0
HFD1_k127_389517_3 - - - - 0.000000000000000703 83.0
HFD1_k127_389517_4 DNA integration - - - 0.000000000000004511 78.0
HFD1_k127_389517_6 Staphylococcal nuclease homologues K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.00000000004904 66.0
HFD1_k127_389517_7 COG2356 Endonuclease I K01150 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005576,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0042597,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.21.1 0.00000002479 57.0
HFD1_k127_3981090_0 AcrB/AcrD/AcrF family - - - 0.0 1608.0
HFD1_k127_3981090_1 ATPase activity K01990 - - 4.222e-300 932.0
HFD1_k127_3981090_11 Cytochrome c K12263 - - 0.00000000000000000000271 98.0
HFD1_k127_3981090_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00009243 46.0
HFD1_k127_3981090_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K13525,K17681 - 3.4.21.53 9.03e-282 876.0
HFD1_k127_3981090_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.654e-276 858.0
HFD1_k127_3981090_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 525.0
HFD1_k127_3981090_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 478.0
HFD1_k127_3981090_6 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 460.0
HFD1_k127_3981090_7 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 443.0
HFD1_k127_3981090_8 cellular manganese ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000005069 217.0
HFD1_k127_3981090_9 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000006203 130.0
HFD1_k127_4085045_1 TIGRFAM phosphate binding protein K02040 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 463.0
HFD1_k127_4085045_10 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000008236 154.0
HFD1_k127_4085045_13 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000004721 87.0
HFD1_k127_4085045_15 - - - - 0.00000000000000004548 84.0
HFD1_k127_4085045_16 nuclease - - - 0.00000000000001676 76.0
HFD1_k127_4085045_17 Helix-hairpin-helix motif - - - 0.00000009561 53.0
HFD1_k127_4085045_18 DNA integration - - - 0.00001884 48.0
HFD1_k127_4085045_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 428.0
HFD1_k127_4085045_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 395.0
HFD1_k127_4085045_4 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 395.0
HFD1_k127_4085045_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 327.0
HFD1_k127_4085045_8 identical protein binding K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.000000000000000000000000000000000000000000000000000005965 194.0
HFD1_k127_4085045_9 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000006931 162.0
HFD1_k127_4088222_0 AcrB/AcrD/AcrF family - - - 0.0 1655.0
HFD1_k127_4116345_0 Peptidase M36 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 320.0
HFD1_k127_4116345_1 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000001663 180.0
HFD1_k127_4116345_2 RNA recognition motif - - - 0.0000000000000000000000000000000000000000004001 159.0
HFD1_k127_4116345_3 - - - - 0.00000000003637 68.0
HFD1_k127_4181608_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 4.712e-259 804.0
HFD1_k127_4181608_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.566e-241 749.0
HFD1_k127_4181608_2 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 542.0
HFD1_k127_4181608_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 438.0
HFD1_k127_4181608_4 Bacterial protein of unknown function (DUF948) - - - 0.000000000000000000000000000000000000000000000000002791 184.0
HFD1_k127_4181608_5 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000000000000001312 121.0
HFD1_k127_4181608_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000007035 98.0
HFD1_k127_4184528_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.338e-246 775.0
HFD1_k127_4184528_1 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000005865 110.0
HFD1_k127_4184682_0 Aldehyde dehydrogenase family - - - 2.381e-226 709.0
HFD1_k127_4184682_1 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 612.0
HFD1_k127_4184682_2 arginine decarboxylase activity K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 350.0
HFD1_k127_4184682_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002615 267.0
HFD1_k127_4184682_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000204 149.0
HFD1_k127_4184682_6 DNA integration - - - 0.0001315 44.0
HFD1_k127_4261863_0 Uncharacterized protein family (UPF0051) K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 543.0
HFD1_k127_4261863_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 364.0
HFD1_k127_4261863_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.00000000000000000000000000000000000009153 149.0
HFD1_k127_4261863_13 Belongs to the universal stress protein A family - - - 0.00000000575 67.0
HFD1_k127_4261863_14 Universal stress protein - - - 0.00004273 55.0
HFD1_k127_4261863_2 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 334.0
HFD1_k127_4261863_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 338.0
HFD1_k127_4261863_4 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 287.0
HFD1_k127_4261863_5 Membrane K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 276.0
HFD1_k127_4261863_6 positive regulation of acetylcholine metabolic process K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000003591 239.0
HFD1_k127_4261863_7 PFAM ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000002854 237.0
HFD1_k127_4261863_8 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000006926 200.0
HFD1_k127_4261863_9 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.000000000000000000000000000000000000000006924 159.0
HFD1_k127_4263702_0 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 574.0
HFD1_k127_4263702_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 509.0
HFD1_k127_4263702_2 tRNA processing K04075,K14058,K21947 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.1.15,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 416.0
HFD1_k127_4263702_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005692 282.0
HFD1_k127_4263702_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000002749 212.0
HFD1_k127_4263702_5 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000001061 194.0
HFD1_k127_4263702_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.0000000000000000000000000000000000000000000000001539 183.0
HFD1_k127_4263702_9 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000000002068 104.0
HFD1_k127_4271184_0 Belongs to the TPP enzyme family K09459 - 4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 355.0
HFD1_k127_4271184_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002067 282.0
HFD1_k127_4271184_2 TIGRFAM phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000005039 256.0
HFD1_k127_4273461_0 ATP citrate lyase citrate-binding K15231 - 2.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 520.0
HFD1_k127_4273461_1 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 359.0
HFD1_k127_4273461_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 349.0
HFD1_k127_4273461_4 phosphatase - - - 0.00000000000000000000000000000000000000000005643 163.0
HFD1_k127_4276609_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 598.0
HFD1_k127_4276609_1 dimethylargininase activity K00819 GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813 2.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 422.0
HFD1_k127_4276609_2 pseudouridine synthase activity K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 332.0
HFD1_k127_4276609_3 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000006022 194.0
HFD1_k127_4276609_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K16079,K22110 - - 0.00002509 54.0
HFD1_k127_4279818_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.121e-302 930.0
HFD1_k127_4279818_1 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 434.0
HFD1_k127_4279818_2 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000001204 79.0
HFD1_k127_4299297_0 B12 binding domain - - - 3.853e-317 976.0
HFD1_k127_4299297_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 5.944e-230 714.0
HFD1_k127_4299297_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 545.0
HFD1_k127_4299297_3 FAD binding domain K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 486.0
HFD1_k127_431681_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 1.203e-285 884.0
HFD1_k127_431681_1 CoA carboxylase activity K01969,K13778,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4,6.4.1.5 3.5e-284 879.0
HFD1_k127_431681_10 Enoyl-CoA hydratase/isomerase K13767,K13816 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000006207 256.0
HFD1_k127_431681_11 Methylmalonyl-CoA mutase K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000003207 196.0
HFD1_k127_431681_2 Belongs to the thiolase family K00626 - 2.3.1.9 1.283e-197 622.0
HFD1_k127_431681_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 449.0
HFD1_k127_431681_4 S-acyltransferase activity K00658,K09699 - 2.3.1.168,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 430.0
HFD1_k127_431681_5 3-hydroxyacyl-CoA dehydrogenase K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 419.0
HFD1_k127_431681_6 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 405.0
HFD1_k127_431681_7 Belongs to the alpha-IPM synthase homocitrate synthase family K01640,K01968 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 398.0
HFD1_k127_431681_8 isobutyryl-CoA mutase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 327.0
HFD1_k127_431681_9 Enoyl-CoA hydratase K13766,K13779 - 4.2.1.18,4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001272 278.0
HFD1_k127_4355498_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 2053.0
HFD1_k127_4355498_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1195.0
HFD1_k127_4355498_10 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 594.0
HFD1_k127_4355498_11 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 553.0
HFD1_k127_4355498_12 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 522.0
HFD1_k127_4355498_13 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 493.0
HFD1_k127_4355498_14 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 490.0
HFD1_k127_4355498_15 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 432.0
HFD1_k127_4355498_16 23S rRNA (guanine(2445)-N(2))-methyltransferase activity K07444,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 438.0
HFD1_k127_4355498_17 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 434.0
HFD1_k127_4355498_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 411.0
HFD1_k127_4355498_19 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 399.0
HFD1_k127_4355498_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.695e-316 980.0
HFD1_k127_4355498_20 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 393.0
HFD1_k127_4355498_21 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 393.0
HFD1_k127_4355498_22 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 385.0
HFD1_k127_4355498_23 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 382.0
HFD1_k127_4355498_24 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 346.0
HFD1_k127_4355498_25 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 336.0
HFD1_k127_4355498_26 oxidoreductase activity K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 335.0
HFD1_k127_4355498_27 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 314.0
HFD1_k127_4355498_28 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 295.0
HFD1_k127_4355498_29 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000005168 250.0
HFD1_k127_4355498_3 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 5.118e-277 857.0
HFD1_k127_4355498_30 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000001746 237.0
HFD1_k127_4355498_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000387 237.0
HFD1_k127_4355498_32 ACT domain - - - 0.000000000000000000000000000000000000000000000000000000000000002394 219.0
HFD1_k127_4355498_33 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000181 216.0
HFD1_k127_4355498_35 LysM domain - - - 0.0000000000000000000000000000000000000000000000004142 184.0
HFD1_k127_4355498_36 protein disulfide oxidoreductase activity K03673 - - 0.0000000000000000000000000000000000000000000003583 173.0
HFD1_k127_4355498_37 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000001163 166.0
HFD1_k127_4355498_4 radical SAM domain protein - - - 4.155e-271 852.0
HFD1_k127_4355498_41 nuclease activity K06218 - - 0.000000000000000000000000000002858 121.0
HFD1_k127_4355498_44 peptidyl-tyrosine sulfation K02450 - - 0.000000000000000000000319 108.0
HFD1_k127_4355498_5 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 6.543e-265 822.0
HFD1_k127_4355498_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.959e-224 701.0
HFD1_k127_4355498_7 deoxyhypusine monooxygenase activity K08884 - 2.7.11.1 2.204e-207 664.0
HFD1_k127_4355498_8 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.851e-204 644.0
HFD1_k127_4355498_9 MacB-like periplasmic core domain K09808 - - 7.757e-202 635.0
HFD1_k127_4372792_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 1.717e-257 801.0
HFD1_k127_4372792_1 B3/4 domain K01890 - 6.1.1.20 3.781e-254 798.0
HFD1_k127_4372792_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 452.0
HFD1_k127_4372792_3 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 443.0
HFD1_k127_4372792_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 333.0
HFD1_k127_4372792_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000102 136.0
HFD1_k127_4378780_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0 1183.0
HFD1_k127_4378780_1 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 3.37e-277 861.0
HFD1_k127_4378780_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 442.0
HFD1_k127_4378780_11 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 437.0
HFD1_k127_4378780_12 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 391.0
HFD1_k127_4378780_13 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 360.0
HFD1_k127_4378780_14 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005833 260.0
HFD1_k127_4378780_15 Belongs to the TPP enzyme family K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000656 234.0
HFD1_k127_4378780_16 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000007836 125.0
HFD1_k127_4378780_18 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000001357 96.0
HFD1_k127_4378780_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.829e-210 665.0
HFD1_k127_4378780_21 EamA-like transporter family - - - 0.000000004947 68.0
HFD1_k127_4378780_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 1.083e-199 636.0
HFD1_k127_4378780_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 612.0
HFD1_k127_4378780_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 602.0
HFD1_k127_4378780_6 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 568.0
HFD1_k127_4378780_7 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 569.0
HFD1_k127_4378780_8 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 539.0
HFD1_k127_4378780_9 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 525.0
HFD1_k127_4399629_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.951e-239 743.0
HFD1_k127_4399629_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 592.0
HFD1_k127_4399629_2 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 486.0
HFD1_k127_4399629_3 response regulator K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 329.0
HFD1_k127_4399629_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000000000000000000003231 250.0
HFD1_k127_4399629_6 regulation of DNA repair K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.00000000000000000000000000001422 123.0
HFD1_k127_4399629_7 peroxidase activity - - - 0.00000000000000005929 81.0
HFD1_k127_443104_0 Glutathione S-transferase K00799,K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7,2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 439.0
HFD1_k127_443104_1 - - - - 0.0000000000000000000000001172 117.0
HFD1_k127_443104_2 Aminoacyl-tRNA editing domain K19055 - - 0.000000000003081 69.0
HFD1_k127_4433487_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 526.0
HFD1_k127_4433487_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 521.0
HFD1_k127_4433487_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 351.0
HFD1_k127_4433487_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000003495 196.0
HFD1_k127_4433487_4 translation initiation factor activity K03407,K03646,K04065,K06596,K07277,K12065,K13593 - 2.7.13.3 0.000000000000000000000000000000003599 140.0
HFD1_k127_4433487_5 two component, sigma54 specific, transcriptional regulator, Fis family K07714,K07715 - - 0.0000000000000003375 84.0
HFD1_k127_4436340_0 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 405.0
HFD1_k127_4436340_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 361.0
HFD1_k127_4436340_2 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 293.0
HFD1_k127_4436340_3 protein histidine kinase activity K07315 - 3.1.3.3 0.000000000000000000000000000001272 129.0
HFD1_k127_4452410_0 Sigma-54 interaction domain K07714 - - 6.228e-241 750.0
HFD1_k127_4452410_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 567.0
HFD1_k127_4452410_2 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 336.0
HFD1_k127_4452410_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 323.0
HFD1_k127_4452410_5 maF-like protein K03215,K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000008035 216.0
HFD1_k127_4452410_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000001999 165.0
HFD1_k127_4452410_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.000001612 51.0
HFD1_k127_44745_0 - - - - 0.0000000000000000000000000000000000000008122 164.0
HFD1_k127_44745_1 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000008555 108.0
HFD1_k127_44745_2 Protein of unknown function (DUF3365) - - - 0.000000000000000000891 100.0
HFD1_k127_44745_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00002464 52.0
HFD1_k127_451789_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 434.0
HFD1_k127_451789_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000005254 240.0
HFD1_k127_452995_0 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000000001062 100.0
HFD1_k127_452995_1 Helix-hairpin-helix motif - - - 0.000000000000000000001732 100.0
HFD1_k127_452995_3 - - - - 0.000000001379 60.0
HFD1_k127_452995_5 - - - - 0.00000001134 64.0
HFD1_k127_452995_7 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00001502 48.0
HFD1_k127_4632385_0 peptidyl-tyrosine sulfation - - - 4.847e-203 681.0
HFD1_k127_4632385_1 protein transport across the cell outer membrane K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003962 267.0
HFD1_k127_4632385_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000003342 151.0
HFD1_k127_4657718_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 0.0 1045.0
HFD1_k127_4657718_1 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00392 - 1.7.7.1,1.8.7.1 1.086e-248 776.0
HFD1_k127_4657718_10 metallopeptidase activity K01637 - 4.1.3.1 0.00003245 53.0
HFD1_k127_4657718_2 NMT1-like family K02051,K15576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 577.0
HFD1_k127_4657718_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 553.0
HFD1_k127_4657718_4 formate transmembrane transporter activity K02598,K06212,K21993 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 423.0
HFD1_k127_4657718_5 Binding-protein-dependent transport system inner membrane component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 362.0
HFD1_k127_4657718_6 PFAM ABC transporter K02049,K15578,K15579 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 357.0
HFD1_k127_4657718_7 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 299.0
HFD1_k127_4657718_8 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000001467 241.0
HFD1_k127_4657718_9 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000002358 215.0
HFD1_k127_4694288_0 Memo-like protein K06990 - - 5.433e-195 616.0
HFD1_k127_4694288_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 612.0
HFD1_k127_4694288_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 484.0
HFD1_k127_4694288_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 446.0
HFD1_k127_4694288_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 401.0
HFD1_k127_4694288_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 381.0
HFD1_k127_4718449_0 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 458.0
HFD1_k127_4718449_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 287.0
HFD1_k127_4718449_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000002046 154.0
HFD1_k127_4732675_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 572.0
HFD1_k127_4739515_0 Protein involved in outer membrane biogenesis K07290 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 461.0
HFD1_k127_4739515_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 287.0
HFD1_k127_4739515_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000006353 50.0
HFD1_k127_4835092_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 587.0
HFD1_k127_4837559_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005126 282.0
HFD1_k127_4837559_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000486 276.0
HFD1_k127_4837559_2 Protein involved in transporter activity K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002029 263.0
HFD1_k127_4837559_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000005415 162.0
HFD1_k127_4837559_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000001593 146.0
HFD1_k127_4837559_5 Redoxin - - - 0.00000000000000000002014 98.0
HFD1_k127_4837559_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000001356 92.0
HFD1_k127_4837559_7 redox protein, regulator of disulfide bond formation - - - 0.00000001214 63.0
HFD1_k127_4837559_8 Redoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000001887 58.0
HFD1_k127_4837559_9 Integrase catalytic - - - 0.000002018 52.0
HFD1_k127_4841933_0 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000174 132.0
HFD1_k127_4841933_1 - - - - 0.000000002205 62.0
HFD1_k127_4851373_0 belongs to the aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 1.415e-233 731.0
HFD1_k127_4851373_1 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 316.0
HFD1_k127_4851373_2 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000006117 245.0
HFD1_k127_4851373_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000006475 166.0
HFD1_k127_4851373_4 Bacterial regulatory protein, Fis family K10943 - - 0.000000000000000000007587 105.0
HFD1_k127_486179_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.684e-281 875.0
HFD1_k127_486179_1 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 299.0
HFD1_k127_486179_2 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000004092 183.0
HFD1_k127_486179_3 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000000000000000000000000000001078 169.0
HFD1_k127_4878586_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1158.0
HFD1_k127_4878586_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1077.0
HFD1_k127_4878586_10 peptidoglycan binding K03642 - - 0.00000000000000000000000000000000000000000000000000009606 196.0
HFD1_k127_4878586_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000009219 85.0
HFD1_k127_4878586_15 - - - - 0.00005936 47.0
HFD1_k127_4878586_2 - K01992 - - 5.284e-236 739.0
HFD1_k127_4878586_4 ATPase activity K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 467.0
HFD1_k127_4878586_5 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 460.0
HFD1_k127_4878586_6 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 384.0
HFD1_k127_4878586_7 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 384.0
HFD1_k127_4914392_0 Conserved carboxylase domain K01960 - 6.4.1.1 0.0 1030.0
HFD1_k127_4914392_1 Biotin carboxylase C-terminal domain K01959 - 6.4.1.1 5.068e-272 841.0
HFD1_k127_4914392_12 fatty acid desaturase K00507 - 1.14.19.1 0.00000004781 54.0
HFD1_k127_4914392_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 370.0
HFD1_k127_4914392_3 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 364.0
HFD1_k127_4914392_4 phosphate ion binding K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 353.0
HFD1_k127_4914392_5 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 330.0
HFD1_k127_4914392_6 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 300.0
HFD1_k127_4914392_9 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000000006703 138.0
HFD1_k127_4950594_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1568.0
HFD1_k127_4950594_1 MacB-like periplasmic core domain K02004 - - 7.433e-212 663.0
HFD1_k127_4950594_10 Regulatory protein, FmdB family - - - 0.000000000000000000000000009148 111.0
HFD1_k127_4950594_11 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000008969 94.0
HFD1_k127_4950594_12 Excisionase - - - 0.00000000006714 64.0
HFD1_k127_4950594_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 509.0
HFD1_k127_4950594_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 374.0
HFD1_k127_4950594_4 Evidence 2b Function of strongly homologous gene K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 364.0
HFD1_k127_4950594_5 photosystem II stabilization K02237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003361 259.0
HFD1_k127_4950594_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000004734 239.0
HFD1_k127_4950594_7 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000007747 238.0
HFD1_k127_4950594_8 crossover junction endodeoxyribonuclease activity K01160 - 3.1.22.4 0.000000000000000000000000000000000000000000001464 171.0
HFD1_k127_4971388_0 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 - 1.4.1.3,1.4.1.4 3.007e-208 651.0
HFD1_k127_4971388_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 579.0
HFD1_k127_4971388_2 Proto-chlorophyllide reductase 57 kD subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 499.0
HFD1_k127_4971388_3 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 404.0
HFD1_k127_4971388_4 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 390.0
HFD1_k127_4971388_6 COG2346, Truncated hemoglobins K06886 - - 0.000000000000000000000000000000000000000000000000000000007696 201.0
HFD1_k127_4971388_8 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000000000000000000001961 164.0
HFD1_k127_5005404_0 Cytochrome c K12263 - - 3.955e-260 806.0
HFD1_k127_5005404_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 557.0
HFD1_k127_5005404_10 Cytochrome c K12263 - - 0.00000000000000000000000000004098 121.0
HFD1_k127_5005404_12 response regulator - - - 0.00000000000000364 82.0
HFD1_k127_5005404_14 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain - - - 0.0000001494 57.0
HFD1_k127_5005404_16 - - - - 0.0005415 48.0
HFD1_k127_5005404_17 cheY-homologous receiver domain - - - 0.0007031 47.0
HFD1_k127_5005404_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 529.0
HFD1_k127_5005404_3 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 374.0
HFD1_k127_5005404_4 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 362.0
HFD1_k127_5005404_5 Product type r regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 304.0
HFD1_k127_5005404_6 Cytochrome c K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004373 250.0
HFD1_k127_5005404_7 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000000000000000005126 215.0
HFD1_k127_5005404_8 - K07112 - - 0.00000000000000000000000000000000000000002064 163.0
HFD1_k127_5005404_9 overlaps another CDS with the same product name K07112 - - 0.000000000000000000000000000000000003163 144.0
HFD1_k127_5006832_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.0 1631.0
HFD1_k127_5006832_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 4.383e-283 880.0
HFD1_k127_5006832_2 Protein involved in amylo-alpha-1,6-glucosidase activity and glycogen biosynthetic process - - - 7.663e-222 714.0
HFD1_k127_5006832_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000001952 146.0
HFD1_k127_5011803_0 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 571.0
HFD1_k127_5011803_1 Pilus assembly protein PilX K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 370.0
HFD1_k127_5011803_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 339.0
HFD1_k127_5011803_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 313.0
HFD1_k127_5011803_4 pilus assembly protein PilW K02672 - - 0.000000000000000000000000000000000000000009649 164.0
HFD1_k127_5011803_5 response regulator K03413 - - 0.000000000000000000000000000000002537 130.0
HFD1_k127_5011803_6 Putative Competence protein ComGF K02246,K02248 - - 0.000000000000000000000000000000003777 136.0
HFD1_k127_5059251_0 RNA-3'-phosphate cyclase activity K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 352.0
HFD1_k127_5059251_1 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006955 268.0
HFD1_k127_5059251_2 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000001952 204.0
HFD1_k127_5059251_3 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000006206 169.0
HFD1_k127_5059251_4 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000002138 115.0
HFD1_k127_5073433_0 acid synthase K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 362.0
HFD1_k127_5073433_1 Acetyltransferase GNAT family - - - 0.0000000000000000000000000000000003531 138.0
HFD1_k127_5073433_2 Spore coat polysaccharide biosynthesis protein - - - 0.00000002358 58.0
HFD1_k127_5082223_0 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000000000000000000000006495 220.0
HFD1_k127_5082223_1 Amidase - - - 0.0000000000000000000000000000000001045 139.0
HFD1_k127_5089697_0 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 316.0
HFD1_k127_5089697_1 cellulose binding - - - 0.00000000000000001335 91.0
HFD1_k127_5091167_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 5.293e-303 940.0
HFD1_k127_5091167_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.461e-268 829.0
HFD1_k127_5091167_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 346.0
HFD1_k127_5091167_11 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 321.0
HFD1_k127_5091167_12 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 313.0
HFD1_k127_5091167_13 phosphogluconate dehydrogenase (decarboxylating) activity K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 313.0
HFD1_k127_5091167_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001151 267.0
HFD1_k127_5091167_15 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000004582 252.0
HFD1_k127_5091167_16 MEKHLA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004228 224.0
HFD1_k127_5091167_18 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000002515 181.0
HFD1_k127_5091167_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 9.112e-233 730.0
HFD1_k127_5091167_22 protein conserved in bacteria - - - 0.000000000000000000000005981 108.0
HFD1_k127_5091167_24 - - - - 0.0001591 47.0
HFD1_k127_5091167_3 Type II/IV secretion system protein K02454,K02652 - - 6.779e-204 647.0
HFD1_k127_5091167_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00520 - 1.16.1.1 1.714e-198 627.0
HFD1_k127_5091167_5 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 573.0
HFD1_k127_5091167_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 455.0
HFD1_k127_5091167_7 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 385.0
HFD1_k127_5091167_8 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 369.0
HFD1_k127_5091167_9 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 346.0
HFD1_k127_509465_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 609.0
HFD1_k127_509465_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 604.0
HFD1_k127_509465_10 Pyruvate kinase K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 312.0
HFD1_k127_509465_11 Histidine kinase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 310.0
HFD1_k127_509465_12 IMP dehydrogenase activity K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000001509 238.0
HFD1_k127_509465_14 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000561 206.0
HFD1_k127_509465_15 Protein conserved in bacteria K09984 - - 0.000000000000000000000000000000000000000000000000000000004057 200.0
HFD1_k127_509465_16 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000002576 201.0
HFD1_k127_509465_17 translation initiation factor activity K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000002103 181.0
HFD1_k127_509465_18 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000001002 164.0
HFD1_k127_509465_19 conserved protein (DUF2132) K06867 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000002085 126.0
HFD1_k127_509465_2 ATP:ADP antiporter activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 521.0
HFD1_k127_509465_21 cytochrome C peroxidase - - - 0.0000000004356 64.0
HFD1_k127_509465_3 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 486.0
HFD1_k127_509465_4 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 460.0
HFD1_k127_509465_5 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 436.0
HFD1_k127_509465_6 protein-(glutamine-N5) methyltransferase activity K00543,K16130,K18896,K18897,K21515 - 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 428.0
HFD1_k127_509465_7 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 426.0
HFD1_k127_509465_8 signal-transduction protein containing cAMP-binding and CBS domains K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 372.0
HFD1_k127_509465_9 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 331.0
HFD1_k127_5102208_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 334.0
HFD1_k127_5102208_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 299.0
HFD1_k127_5102208_2 peptide catabolic process - - - 0.0000005936 57.0
HFD1_k127_5104249_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 2.344e-248 777.0
HFD1_k127_5104249_1 Aminotransferase class-III K01845 - 5.4.3.8 8.538e-204 642.0
HFD1_k127_5104249_10 endoribonuclease activity K03628,K15125 GO:0005575,GO:0005576 - 0.000000000000000000000000047 116.0
HFD1_k127_5104249_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 418.0
HFD1_k127_5104249_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 369.0
HFD1_k127_5104249_4 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 374.0
HFD1_k127_5104249_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 359.0
HFD1_k127_5104249_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002487 280.0
HFD1_k127_5104249_8 (Barnase) inhibitor - - - 0.0000000000000000000000000000000000000000000003104 172.0
HFD1_k127_5121692_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1411.0
HFD1_k127_5121692_1 PD-(D/E)XK nuclease superfamily - - - 0.0 1052.0
HFD1_k127_5121692_11 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002136 267.0
HFD1_k127_5121692_12 - K07184,K07777,K12065,K13527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000002399 253.0
HFD1_k127_5121692_13 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000004542 249.0
HFD1_k127_5121692_16 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000007087 166.0
HFD1_k127_5121692_17 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000003066 162.0
HFD1_k127_5121692_18 Protein of unknown function (DUF423) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000001059 160.0
HFD1_k127_5121692_19 photosynthesis - - - 0.0000000000000000000000000000000000762 140.0
HFD1_k127_5121692_2 Type III restriction enzyme res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 5.059e-253 788.0
HFD1_k127_5121692_20 Saccharopine dehydrogenase NADP binding domain K00290 - 1.5.1.7 0.0000000000000000000000000000000138 141.0
HFD1_k127_5121692_21 sequence-specific DNA binding - - - 0.0000000000000000000000000000002149 125.0
HFD1_k127_5121692_24 Glycosyl transferase family 41 K09667 - 2.4.1.255 0.000000000000000000000003048 117.0
HFD1_k127_5121692_25 gas vesicle protein - - - 0.000000000000000001782 88.0
HFD1_k127_5121692_3 Bacterial regulatory protein, Fis family K07715 - - 1.208e-234 732.0
HFD1_k127_5121692_4 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 3.326e-226 710.0
HFD1_k127_5121692_5 Pas domain K01768,K07315 - 3.1.3.3,4.6.1.1 2.234e-194 621.0
HFD1_k127_5121692_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 606.0
HFD1_k127_5121692_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 410.0
HFD1_k127_5121692_8 Alpha/beta hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 391.0
HFD1_k127_5121692_9 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 363.0
HFD1_k127_5125282_0 Aminotransferase class-III K00823,K03918,K20428,K20435 - 2.6.1.19,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 602.0
HFD1_k127_5125282_1 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 361.0
HFD1_k127_5125282_2 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000001146 227.0
HFD1_k127_5125282_4 spectrin binding K15502,K19947 - 1.14.13.225 0.00006845 52.0
HFD1_k127_5126434_0 Amino acid permease K03294 - - 1.708e-247 771.0
HFD1_k127_5126434_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.42e-242 757.0
HFD1_k127_5126434_10 Phosphoserine phosphatase - - - 0.00000000000000000000000000000000000000000000000000001364 191.0
HFD1_k127_5126434_13 deoxyhypusine monooxygenase activity K05386 - - 0.00000000000000000000000000000003256 136.0
HFD1_k127_5126434_2 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 557.0
HFD1_k127_5126434_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 514.0
HFD1_k127_5126434_4 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 372.0
HFD1_k127_5126434_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 332.0
HFD1_k127_5126434_6 protein secretion K03116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 292.0
HFD1_k127_5126434_7 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003706 267.0
HFD1_k127_5126434_8 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000000000000000000000392 233.0
HFD1_k127_5126434_9 - - - - 0.000000000000000000000000000000000000000000000000000001301 196.0
HFD1_k127_5190870_0 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000009479 141.0
HFD1_k127_5190870_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000009322 130.0
HFD1_k127_5190870_2 Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.0000000000000000000001867 98.0
HFD1_k127_5190870_3 electron transfer activity K05337,K17247 - - 0.0000000000000000000003138 98.0
HFD1_k127_5190870_4 - - - - 0.0000000000000000003807 94.0
HFD1_k127_5190870_5 TRAP transporter solute receptor TAXI family - - - 0.000000000000001269 79.0
HFD1_k127_5190870_6 Sodium Bile acid symporter family K03453 - - 0.00000000002734 65.0
HFD1_k127_5209330_0 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 396.0
HFD1_k127_5209330_1 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008602 287.0
HFD1_k127_5209330_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002274 280.0
HFD1_k127_5209330_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000002743 235.0
HFD1_k127_5209330_4 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000001955 188.0
HFD1_k127_5209330_5 Transposase IS66 family K07484 - - 0.00000000000000000000000000000000001606 140.0
HFD1_k127_5209330_6 Transposase K07484 - - 0.000000000000000000000000000007728 126.0
HFD1_k127_5209330_7 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000008604 116.0
HFD1_k127_5209330_8 integral membrane protein - - - 0.0000000000000009243 79.0
HFD1_k127_5241661_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1135.0
HFD1_k127_5241661_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 508.0
HFD1_k127_5241661_2 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 518.0
HFD1_k127_5241661_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 500.0
HFD1_k127_5241661_4 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003882 259.0
HFD1_k127_5241661_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002102 248.0
HFD1_k127_5241661_6 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000003195 222.0
HFD1_k127_5241661_7 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000000000000000741 211.0
HFD1_k127_5359221_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0 1104.0
HFD1_k127_5359221_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 5.719e-320 986.0
HFD1_k127_5359221_10 RNA-DNA hybrid ribonuclease activity K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 341.0
HFD1_k127_5359221_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 327.0
HFD1_k127_5359221_12 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 319.0
HFD1_k127_5359221_13 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 308.0
HFD1_k127_5359221_14 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 307.0
HFD1_k127_5359221_15 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 307.0
HFD1_k127_5359221_16 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009905 281.0
HFD1_k127_5359221_18 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000004042 171.0
HFD1_k127_5359221_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 6.126e-242 762.0
HFD1_k127_5359221_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.633e-223 698.0
HFD1_k127_5359221_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.232e-203 638.0
HFD1_k127_5359221_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 578.0
HFD1_k127_5359221_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 458.0
HFD1_k127_5359221_7 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 406.0
HFD1_k127_5359221_8 metalloendopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 406.0
HFD1_k127_5359221_9 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 377.0
HFD1_k127_5393969_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 7.918e-262 811.0
HFD1_k127_5393969_1 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000000000000000000000000000001093 170.0
HFD1_k127_5403024_0 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 477.0
HFD1_k127_5403024_1 Phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 340.0
HFD1_k127_5403024_2 metal cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 299.0
HFD1_k127_5403024_3 Ubiquinol--cytochrome c reductase - - - 0.000000000000000000000000000000000000000000000000000000000000001193 222.0
HFD1_k127_5403024_5 Zn peptidase - - - 0.000000000000000000000000000000000000007203 146.0
HFD1_k127_5403138_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 595.0
HFD1_k127_5403138_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 517.0
HFD1_k127_5403138_2 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 512.0
HFD1_k127_5403138_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 430.0
HFD1_k127_5403138_4 phosphoprotein phosphatase activity K01525 GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 332.0
HFD1_k127_5403138_5 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 302.0
HFD1_k127_5403138_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000002996 233.0
HFD1_k127_5403138_7 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000000000000000000000000000000001956 173.0
HFD1_k127_5403138_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000006032 109.0
HFD1_k127_5414196_0 Molydopterin dinucleotide binding domain K00302,K10814 - 1.4.99.5,1.5.3.1 0.0 1485.0
HFD1_k127_5414196_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 3.101e-272 837.0
HFD1_k127_5414196_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000838 166.0
HFD1_k127_5414196_11 Phosphoserine phosphatase - - - 0.000000000000000000000000000000001938 131.0
HFD1_k127_5414196_2 Flagellar Motor Protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 425.0
HFD1_k127_5414196_3 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 405.0
HFD1_k127_5414196_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 381.0
HFD1_k127_5414196_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 340.0
HFD1_k127_5414196_6 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 364.0
HFD1_k127_5414196_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 285.0
HFD1_k127_5414196_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000009878 250.0
HFD1_k127_5414196_9 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000002032 212.0
HFD1_k127_5450074_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 1.228e-202 646.0
HFD1_k127_5450074_1 phosphate ion binding K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 457.0
HFD1_k127_5450074_11 Type II secretion system (T2SS), protein J K02459 - - 0.0000527 53.0
HFD1_k127_5450074_2 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 352.0
HFD1_k127_5450074_3 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000004003 181.0
HFD1_k127_5450074_4 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000007231 139.0
HFD1_k127_5450074_5 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000000000002128 119.0
HFD1_k127_5450074_6 Prokaryotic N-terminal methylation motif - - - 0.00000000000001176 79.0
HFD1_k127_5450074_7 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000157 83.0
HFD1_k127_5450074_9 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000003991 68.0
HFD1_k127_5470411_0 MacB-like periplasmic core domain K02004 - - 6.218e-252 804.0
HFD1_k127_5470411_1 Tetratricopeptide repeat - - - 2.464e-238 743.0
HFD1_k127_5470411_10 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
HFD1_k127_5470411_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000006931 266.0
HFD1_k127_5470411_12 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000004348 257.0
HFD1_k127_5470411_13 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000000000000000004763 159.0
HFD1_k127_5470411_14 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000001259 162.0
HFD1_k127_5470411_15 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001224 154.0
HFD1_k127_5470411_16 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000000003561 148.0
HFD1_k127_5470411_17 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000000007967 136.0
HFD1_k127_5470411_18 response regulator - - - 0.000000000000000000008964 94.0
HFD1_k127_5470411_2 Phosphoglycerate kinase K00927 - 2.7.2.3 1.261e-225 703.0
HFD1_k127_5470411_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 584.0
HFD1_k127_5470411_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 539.0
HFD1_k127_5470411_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 522.0
HFD1_k127_5470411_6 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 514.0
HFD1_k127_5470411_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 400.0
HFD1_k127_5470411_8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 320.0
HFD1_k127_5470411_9 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 319.0
HFD1_k127_5477293_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.089e-196 618.0
HFD1_k127_5477293_1 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 298.0
HFD1_k127_5487690_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 2.711e-310 960.0
HFD1_k127_5487690_1 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 486.0
HFD1_k127_5487690_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003008 230.0
HFD1_k127_5487690_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000007034 162.0
HFD1_k127_5487690_5 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000222 77.0
HFD1_k127_5492051_0 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 573.0
HFD1_k127_5492051_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 499.0
HFD1_k127_5492051_2 pectinesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 456.0
HFD1_k127_5492051_3 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 443.0
HFD1_k127_5492051_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000001183 263.0
HFD1_k127_5492051_6 phosphorelay signal transduction system K02481,K07714 - - 0.0000002203 57.0
HFD1_k127_5492051_7 DNA-sulfur modification-associated - - - 0.000000402 62.0
HFD1_k127_5492282_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1368.0
HFD1_k127_5492282_1 Surface antigen K07277 - - 0.0 1155.0
HFD1_k127_5492282_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00000000000000000000000000000000000000000000000000004902 192.0
HFD1_k127_5492282_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000000000000000000000000003886 190.0
HFD1_k127_5492282_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 553.0
HFD1_k127_5492282_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 488.0
HFD1_k127_5492282_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 460.0
HFD1_k127_5492282_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 433.0
HFD1_k127_5492282_6 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 424.0
HFD1_k127_5492282_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 295.0
HFD1_k127_5492282_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000177 263.0
HFD1_k127_5492282_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000006602 223.0
HFD1_k127_5617562_0 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 406.0
HFD1_k127_5617562_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 342.0
HFD1_k127_5617562_2 AAA domain, putative AbiEii toxin, Type IV TA system K09817,K09820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005318 263.0
HFD1_k127_5617562_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001003 200.0
HFD1_k127_5617562_6 - K07275 - - 0.00000000000000000000000004546 117.0
HFD1_k127_5633423_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 509.0
HFD1_k127_5633423_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001243 246.0
HFD1_k127_5633423_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000001061 228.0
HFD1_k127_5633423_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000007321 98.0
HFD1_k127_5648099_0 Rubrerythrin K22405 - 1.6.3.4 0.0 1236.0
HFD1_k127_5648099_1 Elongator protein 3, MiaB family, Radical SAM - - - 1.22e-316 973.0
HFD1_k127_5648099_2 Iron-sulfur cluster-binding domain - - - 4.662e-281 871.0
HFD1_k127_5648099_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000006149 220.0
HFD1_k127_5649577_0 Peptidase family M1 domain K08776 - - 0.0 1098.0
HFD1_k127_5649577_1 FtsX-like permease family K02004 - - 0.0 1040.0
HFD1_k127_5649577_10 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000002562 274.0
HFD1_k127_5649577_11 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
HFD1_k127_5649577_12 zinc ion binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000003222 243.0
HFD1_k127_5649577_13 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000216 123.0
HFD1_k127_5649577_15 - - - - 0.00000004088 55.0
HFD1_k127_5649577_16 Glucose / Sorbosone dehydrogenase - - - 0.000000237 53.0
HFD1_k127_5649577_2 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 622.0
HFD1_k127_5649577_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 506.0
HFD1_k127_5649577_4 molybdopterin cofactor binding K00370,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 441.0
HFD1_k127_5649577_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 341.0
HFD1_k127_5649577_7 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 333.0
HFD1_k127_5649577_8 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 338.0
HFD1_k127_5649577_9 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 329.0
HFD1_k127_5651772_0 NHL repeat - - - 1.35e-241 752.0
HFD1_k127_5651772_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 446.0
HFD1_k127_5651772_2 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 434.0
HFD1_k127_5651772_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000005342 116.0
HFD1_k127_566010_0 Alkaline phosphatase K01113 - 3.1.3.1 8.064e-232 731.0
HFD1_k127_566010_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 300.0
HFD1_k127_566010_2 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000009959 237.0
HFD1_k127_566010_4 Protein of unknown function (DUF502) - - - 0.00000000000000003185 91.0
HFD1_k127_566010_5 - - - - 0.0000000006789 68.0
HFD1_k127_5661277_0 Type II/IV secretion system protein K02454,K02652 - - 1.436e-303 938.0
HFD1_k127_5661277_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 5.522e-233 726.0
HFD1_k127_5661277_10 Pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002783 273.0
HFD1_k127_5661277_11 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004066 262.0
HFD1_k127_5661277_12 Type ii and iii secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
HFD1_k127_5661277_13 general secretion pathway protein K10927 - - 0.000000000000000000000000000000000000000000000000000000000000000000002232 241.0
HFD1_k127_5661277_15 PFAM Fimbrial assembly family protein K02461,K02662,K02663,K12289 - - 0.0000000000000000000000000000000000000000000000001308 183.0
HFD1_k127_5661277_17 Pfam:N_methyl_2 K02456 - - 0.0000000000000000000000000000000000005802 143.0
HFD1_k127_5661277_19 COG1388 FOG LysM repeat K19220,K19223,K19224 - - 0.000003537 58.0
HFD1_k127_5661277_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 6.335e-205 645.0
HFD1_k127_5661277_3 - - - - 2.853e-196 628.0
HFD1_k127_5661277_4 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 597.0
HFD1_k127_5661277_5 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 546.0
HFD1_k127_5661277_6 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 543.0
HFD1_k127_5661277_7 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 527.0
HFD1_k127_5661277_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 304.0
HFD1_k127_5661277_9 general secretion pathway protein K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003172 270.0
HFD1_k127_5672542_0 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002859 281.0
HFD1_k127_5689838_0 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00392 - 1.7.1.15,1.8.7.1 0.0 1288.0
HFD1_k127_5689838_1 sulfate reduction K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001996 280.0
HFD1_k127_5689838_2 2 iron, 2 sulfur cluster binding K04487,K13643 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000001252 192.0
HFD1_k127_5689838_3 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000008403 190.0
HFD1_k127_5689838_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000008738 146.0
HFD1_k127_5712477_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 519.0
HFD1_k127_5712477_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000239 215.0
HFD1_k127_5712477_2 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000000000000000000006207 126.0
HFD1_k127_5712477_3 Transposase - - - 0.00000004052 54.0
HFD1_k127_5712477_4 DNA-templated transcription, initiation K03088 - - 0.00001324 51.0
HFD1_k127_5712477_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00006289 46.0
HFD1_k127_575350_0 PFAM RNA polymerase sigma factor 54, interaction - - - 2.511e-223 716.0
HFD1_k127_575350_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 7.464e-218 683.0
HFD1_k127_575350_10 PFAM AhpC TSA family - - - 0.00000000000000000000000000000000000000000000005098 178.0
HFD1_k127_575350_12 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000004 147.0
HFD1_k127_575350_13 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000008341 136.0
HFD1_k127_575350_14 TVP38 TMEM64 family inner membrane protein ydjZ - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000004967 141.0
HFD1_k127_575350_16 Outer membrane lipoprotein Slp family K07285 - - 0.000000003942 66.0
HFD1_k127_575350_17 Transmembrane anti-sigma factor - - - 0.0002874 51.0
HFD1_k127_575350_18 YHS domain protein - - - 0.0006693 43.0
HFD1_k127_575350_2 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 527.0
HFD1_k127_575350_3 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 428.0
HFD1_k127_575350_4 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 377.0
HFD1_k127_575350_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 365.0
HFD1_k127_575350_6 Oxidoreductase molybdopterin binding K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 317.0
HFD1_k127_575350_7 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 312.0
HFD1_k127_575350_8 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 303.0
HFD1_k127_575350_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000007646 196.0
HFD1_k127_5759337_0 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000001607 216.0
HFD1_k127_5759337_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.000000000000001188 87.0
HFD1_k127_5759337_2 - - - - 0.000000000000003016 79.0
HFD1_k127_5759337_3 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000005106 77.0
HFD1_k127_5759668_0 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 416.0
HFD1_k127_5759668_1 5'-3' exonuclease, N-terminal resolvase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 396.0
HFD1_k127_5759668_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000008 194.0
HFD1_k127_5759668_3 HEAT repeats - - - 0.000000000000000000000001579 115.0
HFD1_k127_5759668_4 - - - - 0.00000000001768 76.0
HFD1_k127_5765278_0 lipopolysaccharide transport K22110 - - 0.0 1043.0
HFD1_k127_5805187_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 314.0
HFD1_k127_5805187_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000005329 253.0
HFD1_k127_5805187_2 - - - - 0.00000000000000000000000000000000000000000000000000002119 197.0
HFD1_k127_5805187_3 - - - - 0.0000000000000008523 82.0
HFD1_k127_5806449_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 413.0
HFD1_k127_5806449_1 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 305.0
HFD1_k127_5806449_2 PFAM AIG2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000107 261.0
HFD1_k127_5806449_3 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000077 228.0
HFD1_k127_5806449_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000002857 205.0
HFD1_k127_5806449_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000007169 78.0
HFD1_k127_5807111_0 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 381.0
HFD1_k127_5807111_1 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 355.0
HFD1_k127_5807111_2 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000005435 243.0
HFD1_k127_5807111_3 Protein of unknown function (DUF429) - - - 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
HFD1_k127_5807111_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.000000000000000001257 90.0
HFD1_k127_5808465_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.54e-208 656.0
HFD1_k127_5808465_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 449.0
HFD1_k127_5808465_10 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000006098 83.0
HFD1_k127_5808465_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 397.0
HFD1_k127_5808465_4 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006261 259.0
HFD1_k127_5808465_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000001502 201.0
HFD1_k127_5808465_6 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000006697 186.0
HFD1_k127_5808465_7 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000002299 171.0
HFD1_k127_5808465_8 Sulfurtransferase TusA - - - 0.00000000000000000000000000007462 117.0
HFD1_k127_5808465_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000001644 86.0
HFD1_k127_5834506_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 7.524e-308 953.0
HFD1_k127_5834506_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 7.344e-230 723.0
HFD1_k127_5834506_10 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000005379 183.0
HFD1_k127_5834506_11 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000002263 168.0
HFD1_k127_5834506_12 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000003109 153.0
HFD1_k127_5834506_13 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000000000000000000872 130.0
HFD1_k127_5834506_14 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000008688 129.0
HFD1_k127_5834506_15 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000006064 111.0
HFD1_k127_5834506_16 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000005605 104.0
HFD1_k127_5834506_17 - - - - 0.000000000000004908 84.0
HFD1_k127_5834506_18 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000002886 63.0
HFD1_k127_5834506_19 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0030246,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048029,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0002209 47.0
HFD1_k127_5834506_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.17e-198 621.0
HFD1_k127_5834506_3 Glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 544.0
HFD1_k127_5834506_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 515.0
HFD1_k127_5834506_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 498.0
HFD1_k127_5834506_6 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 390.0
HFD1_k127_5834506_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 377.0
HFD1_k127_5834506_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003154 243.0
HFD1_k127_5834506_9 Belongs to the ParB family K03497 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000006485 205.0
HFD1_k127_5859452_0 dicarboxylic acid transport K03309 - - 8.25e-219 686.0
HFD1_k127_5859452_1 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 580.0
HFD1_k127_5859452_2 Belongs to the urease K01429,K14048 - 3.5.1.5 0.0000000000000000000000000000000000000000002402 163.0
HFD1_k127_5859452_3 urea catabolic process K01430 - 3.5.1.5 0.000000000000000000000000000000000000000002754 156.0
HFD1_k127_5859452_4 peptidase m48, ste24p - - - 0.00000000000000000004817 96.0
HFD1_k127_5859452_5 - - - - 0.000000000000000001533 98.0
HFD1_k127_5859452_6 - - - - 0.0000000000000805 81.0
HFD1_k127_5862662_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 5.179e-278 861.0
HFD1_k127_5862662_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 1.344e-250 779.0
HFD1_k127_5862662_10 Histidyl-tRNA synthetase K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 439.0
HFD1_k127_5862662_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 399.0
HFD1_k127_5862662_12 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 312.0
HFD1_k127_5862662_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 302.0
HFD1_k127_5862662_14 pfam abc K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009137 268.0
HFD1_k127_5862662_15 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008378 255.0
HFD1_k127_5862662_16 ABC-2 type transporter K09688,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000201 223.0
HFD1_k127_5862662_17 Glycosyltransferase, group 2 family protein K20444 - - 0.00000000000000000000000000000000000000000000000001148 186.0
HFD1_k127_5862662_18 Cytochrome c K00405 - - 0.0000000000000000000000000000000000000000000002161 173.0
HFD1_k127_5862662_19 response regulator - - - 0.0000000000000000000000000000000000000000001513 169.0
HFD1_k127_5862662_2 Tetratricopeptide repeat - - - 1.569e-230 730.0
HFD1_k127_5862662_20 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000000000000000000000000000004215 129.0
HFD1_k127_5862662_21 PFAM response regulator receiver - - - 0.000000000000000000000000000005554 122.0
HFD1_k127_5862662_22 - - - - 0.00000000000009793 76.0
HFD1_k127_5862662_23 - - - - 0.0000002636 57.0
HFD1_k127_5862662_3 twitching motility protein K02670 - - 2.106e-207 649.0
HFD1_k127_5862662_4 Type II/IV secretion system protein K02669 - - 1.526e-203 636.0
HFD1_k127_5862662_5 Evidence 2b Function of strongly homologous gene - - - 3.194e-203 638.0
HFD1_k127_5862662_6 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 558.0
HFD1_k127_5862662_7 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0030312,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 470.0
HFD1_k127_5862662_8 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 445.0
HFD1_k127_5862662_9 -O-antigen K02847,K13009,K16705 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 461.0
HFD1_k127_5874241_0 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 592.0
HFD1_k127_5874241_1 Sigma-54 interaction domain K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 607.0
HFD1_k127_5874241_10 - - - - 0.0000000000000000000000000000000001662 145.0
HFD1_k127_5874241_11 YCII-related domain - - - 0.0000000000000000001167 92.0
HFD1_k127_5874241_13 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000001039 66.0
HFD1_k127_5874241_2 alcohol dehydrogenase K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 509.0
HFD1_k127_5874241_3 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 358.0
HFD1_k127_5874241_4 Evidence 4 Homologs of previously reported genes of K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 332.0
HFD1_k127_5874241_5 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 321.0
HFD1_k127_5874241_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 301.0
HFD1_k127_5874241_7 response to oxidative stress K04063 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - 0.0000000000000000000000000000000000000000000000000001438 187.0
HFD1_k127_5874241_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000376 172.0
HFD1_k127_5874241_9 Domain of unknown function (DUF5069) - - - 0.000000000000000000000000000000000000000000004101 169.0
HFD1_k127_5897642_0 ABC transporter K06158 - - 0.0 1000.0
HFD1_k127_5897642_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 6.088e-234 729.0
HFD1_k127_5897642_2 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 460.0
HFD1_k127_5897642_3 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 330.0
HFD1_k127_5897642_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 319.0
HFD1_k127_5897642_5 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000000000000000000000000000000000007467 205.0
HFD1_k127_5897642_6 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000139 203.0
HFD1_k127_5897642_8 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.0000000000000000000000000000000000000000000008793 166.0
HFD1_k127_5897642_9 - - - - 0.0006373 44.0
HFD1_k127_5914841_0 peptide catabolic process - - - 6.327e-216 688.0
HFD1_k127_5914841_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 4.086e-206 666.0
HFD1_k127_5914841_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 601.0
HFD1_k127_5914841_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 406.0
HFD1_k127_5914841_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000606 145.0
HFD1_k127_5914841_5 lipid-A-disaccharide synthase activity - - - 0.0000000000000000000000000000000000000136 146.0
HFD1_k127_5914841_6 PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000000000000000000000000000245 158.0
HFD1_k127_5924594_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 7.883e-264 826.0
HFD1_k127_5924594_1 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.000002119 53.0
HFD1_k127_5930016_0 radical SAM domain protein K04034 - 1.21.98.3 2.79e-247 771.0
HFD1_k127_5930016_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.012e-202 643.0
HFD1_k127_5930016_11 - - - - 0.00000000000000000000000000000000000000000000008588 177.0
HFD1_k127_5930016_15 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000001602 139.0
HFD1_k127_5930016_16 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000001558 122.0
HFD1_k127_5930016_18 - - - - 0.000003861 51.0
HFD1_k127_5930016_19 deoxyhypusine monooxygenase activity K05386 - - 0.0002911 52.0
HFD1_k127_5930016_2 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 457.0
HFD1_k127_5930016_3 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 414.0
HFD1_k127_5930016_5 AMP binding K11932 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 255.0
HFD1_k127_5930016_6 signal-transduction protein containing cAMP-binding and CBS domains K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000003257 234.0
HFD1_k127_5930016_7 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.000000000000000000000000000000000000000000000000000000000000000003639 231.0
HFD1_k127_5930016_8 response to oxidative stress K04063 - - 0.000000000000000000000000000000000000000000000000000001091 196.0
HFD1_k127_5930016_9 - K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000001574 188.0
HFD1_k127_5955540_0 helicase activity - - - 0.0 1235.0
HFD1_k127_5955540_1 transferase activity, transferring acyl groups K14658,K17840,K18815 - 2.3.1.59,2.3.1.82 2.301e-305 961.0
HFD1_k127_5955540_2 protein conserved in bacteria K09922 - - 0.0008195 42.0
HFD1_k127_5985164_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000003444 216.0
HFD1_k127_5985164_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000001004 76.0
HFD1_k127_5993230_0 domain, Protein - - - 0.0000000000000000000000000000000000002343 148.0
HFD1_k127_5993230_1 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000000000000002141 140.0
HFD1_k127_5993230_2 PFAM plasmid K06218 - - 0.00000000000000000000001202 102.0
HFD1_k127_5993230_3 Protein of unknown function (DUF2283) - - - 0.00000000000000000001214 92.0
HFD1_k127_5993230_4 Helix-turn-helix domain - - - 0.00000000000000003411 87.0
HFD1_k127_5993230_5 - - - - 0.000000000000001895 78.0
HFD1_k127_5993230_6 Domain of unknown function (DUF4258) - - - 0.00000000004237 65.0
HFD1_k127_6009376_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 334.0
HFD1_k127_6009376_1 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001314 291.0
HFD1_k127_6009376_2 FOG TPR repeat SEL1 subfamily K07126 - - 0.000001204 58.0
HFD1_k127_6009376_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000002725 49.0
HFD1_k127_6009376_4 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00055 46.0
HFD1_k127_6013472_0 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 589.0
HFD1_k127_6013472_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 303.0
HFD1_k127_6013472_2 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000008933 177.0
HFD1_k127_6066962_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000001972 141.0
HFD1_k127_6066962_3 GAF domain - - - 0.00000004357 61.0
HFD1_k127_6066962_4 - - - - 0.000078 52.0
HFD1_k127_6130571_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 595.0
HFD1_k127_6130571_1 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 539.0
HFD1_k127_6130571_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000009283 172.0
HFD1_k127_6181140_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 5.193e-212 665.0
HFD1_k127_6181140_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.299e-206 653.0
HFD1_k127_6181140_10 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000002148 192.0
HFD1_k127_6181140_11 ABC-type transport auxiliary lipoprotein component - - - 0.000000000000000000000000000000000000000000005669 169.0
HFD1_k127_6181140_12 belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.00000000000000000000000000000000000001316 147.0
HFD1_k127_6181140_15 - - - - 0.00000001875 61.0
HFD1_k127_6181140_16 hydrolase family 81 - - - 0.000001232 60.0
HFD1_k127_6181140_17 DNA integration - - - 0.000146 48.0
HFD1_k127_6181140_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 553.0
HFD1_k127_6181140_3 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 554.0
HFD1_k127_6181140_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 482.0
HFD1_k127_6181140_5 nucleotidyltransferase activity K17882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 350.0
HFD1_k127_6181140_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001722 251.0
HFD1_k127_6181140_7 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003394 252.0
HFD1_k127_6181140_8 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000001842 237.0
HFD1_k127_6181140_9 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000157 225.0
HFD1_k127_6222113_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 482.0
HFD1_k127_6222113_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 372.0
HFD1_k127_6270534_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 8.601e-246 774.0
HFD1_k127_6270534_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 551.0
HFD1_k127_6270534_10 Adenosylcobinamide amidohydrolase K02013,K02231 - 2.7.1.156,2.7.7.62,3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 287.0
HFD1_k127_6270534_11 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000000000000000000000000002834 207.0
HFD1_k127_6270534_12 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000000000006706 210.0
HFD1_k127_6270534_13 nuclear chromosome segregation K02666,K03497,K19622 - - 0.00000000000000000000000000000000000000000000000000001393 198.0
HFD1_k127_6270534_14 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000001702 185.0
HFD1_k127_6270534_15 chemotaxis K03408,K03415 - - 0.0000000000000000000000000000000004544 140.0
HFD1_k127_6270534_16 chemotaxis K02659,K03408,K03415,K11524 - - 0.00000000000000000000000008397 112.0
HFD1_k127_6270534_17 cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial K00798 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008817,GO:0009235,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0019842,GO:0031419,GO:0031974,GO:0033013,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 2.5.1.17 0.00000000000000000000006319 106.0
HFD1_k127_6270534_2 Signal transducing histidine kinase, homodimeric domain K02487,K03407,K06596 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 497.0
HFD1_k127_6270534_3 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006237 457.0
HFD1_k127_6270534_4 Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 435.0
HFD1_k127_6270534_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 401.0
HFD1_k127_6270534_6 coenzyme F420-1:gamma-L-glutamate ligase activity K00768,K04719 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79,2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 353.0
HFD1_k127_6270534_7 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 339.0
HFD1_k127_6270534_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 338.0
HFD1_k127_6270534_9 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 340.0
HFD1_k127_6319936_0 PhoQ Sensor - - - 5e-324 1004.0
HFD1_k127_6319936_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.095e-221 699.0
HFD1_k127_6319936_10 carboxylic ester hydrolase activity - - - 0.0000000000000000000000432 104.0
HFD1_k127_6319936_11 Belongs to the ompA family K03640 - - 0.0000004819 59.0
HFD1_k127_6319936_2 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 338.0
HFD1_k127_6319936_3 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 337.0
HFD1_k127_6319936_4 phosphatidylcholine synthase activity K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 335.0
HFD1_k127_6319936_5 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000001087 237.0
HFD1_k127_6319936_6 PFAM Cache K08738 - - 0.000000000000000000000000000000000000000000000000000000000000002019 239.0
HFD1_k127_6319936_7 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000004699 167.0
HFD1_k127_6319936_8 Single Cache domain 2 K07647 - 2.7.13.3 0.0000000000000000000000000000000000000000007384 177.0
HFD1_k127_6319936_9 GYD domain - - - 0.000000000000000000000000000006359 121.0
HFD1_k127_6445989_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 424.0
HFD1_k127_6445989_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0000000000000000000001629 97.0
HFD1_k127_6450079_0 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000001799 164.0
HFD1_k127_6450543_0 protein catabolic process K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.0 1025.0
HFD1_k127_6450543_1 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 5.042e-285 877.0
HFD1_k127_6450543_10 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000006411 199.0
HFD1_k127_6450543_11 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000001777 198.0
HFD1_k127_6450543_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000003546 186.0
HFD1_k127_6450543_13 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.0000000000000000000000000000000000000000000005697 172.0
HFD1_k127_6450543_14 ThiS family K03154 - - 0.000000000000000000002991 95.0
HFD1_k127_6450543_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 2.306e-269 837.0
HFD1_k127_6450543_3 O-methyltransferase activity K13571,K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119,6.3.1.19 3.344e-256 797.0
HFD1_k127_6450543_4 tail specific protease K03797 - 3.4.21.102 3.062e-210 661.0
HFD1_k127_6450543_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 490.0
HFD1_k127_6450543_6 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 442.0
HFD1_k127_6450543_7 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 415.0
HFD1_k127_6450543_8 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 391.0
HFD1_k127_6450543_9 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 332.0
HFD1_k127_6462051_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 559.0
HFD1_k127_6462051_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 295.0
HFD1_k127_6462051_2 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000001381 100.0
HFD1_k127_6482910_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 474.0
HFD1_k127_6482910_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 456.0
HFD1_k127_6482910_2 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 447.0
HFD1_k127_6482910_3 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 334.0
HFD1_k127_6482910_4 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 315.0
HFD1_k127_6484073_0 WD40-like Beta Propeller Repeat K03641 - - 4.143e-236 736.0
HFD1_k127_6484073_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.657e-217 691.0
HFD1_k127_6484073_10 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
HFD1_k127_6484073_11 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000000000000000000000000001306 222.0
HFD1_k127_6484073_12 energy transducer activity K03646,K03832 - - 0.0000000000000000000000000000000000000000000000000008211 197.0
HFD1_k127_6484073_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 535.0
HFD1_k127_6484073_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 412.0
HFD1_k127_6484073_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 372.0
HFD1_k127_6484073_5 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 354.0
HFD1_k127_6484073_6 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 307.0
HFD1_k127_6484073_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 295.0
HFD1_k127_6484073_8 Transposase K01991,K02557,K07161,K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 304.0
HFD1_k127_6484073_9 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
HFD1_k127_65101_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 363.0
HFD1_k127_65101_1 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 329.0
HFD1_k127_65101_2 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000005255 209.0
HFD1_k127_65101_3 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000008921 188.0
HFD1_k127_65101_4 bacterial (prokaryotic) histone like domain K04764 - - 0.000000000000000000000000000000000000000000000003892 174.0
HFD1_k127_65101_5 Recombinase - - - 0.0003641 43.0
HFD1_k127_6553142_0 PFAM Type II secretion system protein E K02283,K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
HFD1_k127_6553142_1 PFAM TadE family protein - - - 0.000000000000000000000000000000000000000000000000001387 196.0
HFD1_k127_6553142_2 Flp pilus assembly protein, ATPase CpaE K02282 - - 0.00000000000000000000000000000000000001692 159.0
HFD1_k127_6553142_3 PFAM TadE family protein - - - 0.0000000000000000001495 93.0
HFD1_k127_6571482_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 6.496e-227 710.0
HFD1_k127_6571482_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 2.226e-215 679.0
HFD1_k127_6571482_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 314.0
HFD1_k127_6602228_0 Type ii secretion system protein e K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 567.0
HFD1_k127_6602228_1 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008963 246.0
HFD1_k127_6602228_2 PFAM Type II secretion system F K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004352 248.0
HFD1_k127_6602228_3 PFAM type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000886 239.0
HFD1_k127_6615460_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.241e-251 783.0
HFD1_k127_6615460_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 2.435e-247 774.0
HFD1_k127_6615460_10 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 465.0
HFD1_k127_6615460_11 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 460.0
HFD1_k127_6615460_12 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 446.0
HFD1_k127_6615460_13 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 415.0
HFD1_k127_6615460_14 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 402.0
HFD1_k127_6615460_15 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 392.0
HFD1_k127_6615460_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 373.0
HFD1_k127_6615460_17 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 353.0
HFD1_k127_6615460_18 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 338.0
HFD1_k127_6615460_19 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 329.0
HFD1_k127_6615460_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 4.119e-243 754.0
HFD1_k127_6615460_20 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 300.0
HFD1_k127_6615460_21 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001325 281.0
HFD1_k127_6615460_22 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001838 280.0
HFD1_k127_6615460_23 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000644 262.0
HFD1_k127_6615460_24 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002122 256.0
HFD1_k127_6615460_25 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001112 241.0
HFD1_k127_6615460_26 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000003232 240.0
HFD1_k127_6615460_27 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000009226 233.0
HFD1_k127_6615460_28 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000000002992 222.0
HFD1_k127_6615460_29 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000000346 212.0
HFD1_k127_6615460_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 4.457e-230 717.0
HFD1_k127_6615460_30 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000009084 196.0
HFD1_k127_6615460_31 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000000000000000000000000000000000000000000009627 198.0
HFD1_k127_6615460_32 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000002278 174.0
HFD1_k127_6615460_33 YGGT family K02221 - - 0.0000000000000000000000000000000000000000006689 159.0
HFD1_k127_6615460_35 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000002126 133.0
HFD1_k127_6615460_36 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001913 99.0
HFD1_k127_6615460_37 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000005186 88.0
HFD1_k127_6615460_38 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000005769 79.0
HFD1_k127_6615460_4 Type II secretion system (T2SS), protein F K02455,K02653 - - 3.649e-208 652.0
HFD1_k127_6615460_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 8.327e-200 633.0
HFD1_k127_6615460_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 562.0
HFD1_k127_6615460_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 534.0
HFD1_k127_6615460_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 530.0
HFD1_k127_6615460_9 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 511.0
HFD1_k127_6629902_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 583.0
HFD1_k127_6629902_1 phosphorelay signal transduction system K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 479.0
HFD1_k127_6632712_0 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 8.629e-276 857.0
HFD1_k127_6632712_1 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 442.0
HFD1_k127_6632712_2 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 442.0
HFD1_k127_6632712_3 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003077 248.0
HFD1_k127_6632712_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000002585 131.0
HFD1_k127_6632712_5 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000009978 93.0
HFD1_k127_6672487_0 silver ion transport K15726 - - 1.954e-228 712.0
HFD1_k127_6672487_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 458.0
HFD1_k127_667779_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 2.54e-274 850.0
HFD1_k127_667779_1 Sugar (and other) transporter K08178 - - 1.133e-213 670.0
HFD1_k127_667779_10 Histidine kinase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002057 261.0
HFD1_k127_667779_11 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000263 177.0
HFD1_k127_667779_2 Evidence 2b Function of strongly homologous gene K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 536.0
HFD1_k127_667779_3 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 525.0
HFD1_k127_667779_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 454.0
HFD1_k127_667779_5 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 339.0
HFD1_k127_667779_6 heat shock protein binding K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 316.0
HFD1_k127_667779_7 ADP-glyceromanno-heptose 6-epimerase activity K00311 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 291.0
HFD1_k127_667779_8 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001004 289.0
HFD1_k127_667779_9 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007296 275.0
HFD1_k127_6680294_0 sigma factor activity K03088 - - 5.587e-196 618.0
HFD1_k127_6680294_1 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 329.0
HFD1_k127_6680294_2 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008497 247.0
HFD1_k127_6680294_3 polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002617 233.0
HFD1_k127_6680294_4 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000003825 195.0
HFD1_k127_6680294_5 YCII-related domain - - - 0.0000000000000000000000000000000000000000000003007 169.0
HFD1_k127_6680294_7 RNA signal recognition particle 4.5S RNA - - - 0.00000000001203 65.0
HFD1_k127_6680294_8 Protein of unknown function (DUF1428) - - - 0.0007322 46.0
HFD1_k127_6717824_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 593.0
HFD1_k127_6717824_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 569.0
HFD1_k127_6717824_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000004001 183.0
HFD1_k127_6717824_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000001043 174.0
HFD1_k127_6717824_6 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000008156 98.0
HFD1_k127_6722589_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 3.163e-267 826.0
HFD1_k127_6722589_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 485.0
HFD1_k127_6722589_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 287.0
HFD1_k127_6722589_3 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000002636 218.0
HFD1_k127_6750472_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.329e-222 703.0
HFD1_k127_6750472_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000001285 215.0
HFD1_k127_6750472_3 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000008915 94.0
HFD1_k127_6768266_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0000166,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0050661,GO:0050662,GO:0055114,GO:0061458,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 402.0
HFD1_k127_6768266_1 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000002911 221.0
HFD1_k127_6768266_2 IMP dehydrogenase activity K09137 - - 0.0000000000000000000000000000000000000000000735 167.0
HFD1_k127_6769723_0 Belongs to the RtcB family K14415 - 6.5.1.3 8.577e-228 713.0
HFD1_k127_6769723_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 468.0
HFD1_k127_6769723_10 THUMP - - - 0.0000000000000000000000000003132 121.0
HFD1_k127_6769723_11 Bacterial PH domain - - - 0.000000000000000000000000003452 119.0
HFD1_k127_6769723_12 8-oxoguanine DNA glycosylase K01247,K13529 - 3.2.2.21 0.0000000008496 70.0
HFD1_k127_6769723_2 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 391.0
HFD1_k127_6769723_3 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 384.0
HFD1_k127_6769723_4 saccharopine dehydrogenase activity K03340 - 1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 358.0
HFD1_k127_6769723_5 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000001254 199.0
HFD1_k127_6769723_6 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000001434 191.0
HFD1_k127_6769723_7 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000001094 171.0
HFD1_k127_6769723_9 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000001557 133.0
HFD1_k127_6876441_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 2.118e-232 726.0
HFD1_k127_6876441_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 9.698e-231 730.0
HFD1_k127_6876441_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 473.0
HFD1_k127_6876441_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 362.0
HFD1_k127_6876441_4 Protein involved in outer membrane biogenesis K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 364.0
HFD1_k127_6876441_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000001119 215.0
HFD1_k127_6876441_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000001916 168.0
HFD1_k127_6876441_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000002784 141.0
HFD1_k127_6883483_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 1023.0
HFD1_k127_6883483_1 Protein involved in outer membrane biogenesis K07290 - - 6.12e-299 940.0
HFD1_k127_6883483_2 transmembrane transporter activity K03535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 514.0
HFD1_k127_6883483_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001248 280.0
HFD1_k127_6883483_4 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000008167 207.0
HFD1_k127_6961338_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 442.0
HFD1_k127_6961338_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 380.0
HFD1_k127_6961338_10 - - - - 0.0003809 48.0
HFD1_k127_6961338_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 348.0
HFD1_k127_6961338_3 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005262 271.0
HFD1_k127_6961338_4 - - - - 0.00000000000000000000000000000000000000000000001732 180.0
HFD1_k127_6961338_7 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000009194 74.0
HFD1_k127_6961338_8 phosphorelay signal transduction system - - - 0.0000585 47.0
HFD1_k127_6961338_9 PFAM blue (type 1) copper domain protein - - - 0.0002546 52.0
HFD1_k127_70224_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 302.0
HFD1_k127_7092254_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0 1482.0
HFD1_k127_7092254_1 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 1.639e-266 826.0
HFD1_k127_7092254_11 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.0000000000000000000000000000000000001253 144.0
HFD1_k127_7092254_12 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000001696 140.0
HFD1_k127_7092254_2 NADH-quinone oxidoreductase K00341,K05577 - 1.6.5.3 3.895e-241 758.0
HFD1_k127_7092254_3 NADH-quinone oxidoreductase K00341,K05577 - 1.6.5.3 6.745e-224 708.0
HFD1_k127_7092254_4 Histidyl-tRNA synthetase K01892 - 6.1.1.21 5.329e-198 625.0
HFD1_k127_7092254_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 2.798e-194 610.0
HFD1_k127_7092254_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 479.0
HFD1_k127_7092254_7 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 460.0
HFD1_k127_7092254_8 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000001005 199.0
HFD1_k127_7092254_9 Uncharacterized conserved protein (DUF2294) - - - 0.0000000000000000000000000000000000000000000000007297 176.0
HFD1_k127_711383_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.0 1038.0
HFD1_k127_711383_1 ATP-grasp domain K01905,K22224 - 6.2.1.13 3.892e-268 843.0
HFD1_k127_711383_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000001938 216.0
HFD1_k127_711383_12 ATP synthase K02115 - - 0.0000000000000000000000000000000000000000000000000000001686 210.0
HFD1_k127_711383_13 epsilon subunit K02114 - - 0.000000000000000000000000000000000000000006655 158.0
HFD1_k127_711383_14 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000000000006095 139.0
HFD1_k127_711383_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000001437 132.0
HFD1_k127_711383_16 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000000000000001839 121.0
HFD1_k127_711383_17 Cytochrome c K02305,K17223 - - 0.000000000000000000000000001651 117.0
HFD1_k127_711383_18 PFAM Cytochrome C - - - 0.0000000003156 66.0
HFD1_k127_711383_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.713e-224 703.0
HFD1_k127_711383_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 6.179e-217 681.0
HFD1_k127_711383_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.677e-211 665.0
HFD1_k127_711383_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 523.0
HFD1_k127_711383_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 386.0
HFD1_k127_711383_7 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 283.0
HFD1_k127_711383_8 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000135 220.0
HFD1_k127_711383_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000000001783 220.0
HFD1_k127_7127989_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0 1272.0
HFD1_k127_7127989_1 von Willebrand factor (vWF) type A domain K02448 - - 0.0 1063.0
HFD1_k127_7127989_10 Pfam:DUF989 - - - 0.0000000000000000000000000000000002928 132.0
HFD1_k127_7127989_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000004194 129.0
HFD1_k127_7127989_12 DUF167 K09131 - - 0.0000000000000000000008341 105.0
HFD1_k127_7127989_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 500.0
HFD1_k127_7127989_3 Associated with various cellular activities K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 469.0
HFD1_k127_7127989_4 Uncharacterised conserved protein (DUF2156) K01163,K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 467.0
HFD1_k127_7127989_5 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000261 246.0
HFD1_k127_7127989_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007943 233.0
HFD1_k127_7127989_7 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000000006198 179.0
HFD1_k127_7127989_9 diguanylate cyclase - - - 0.000000000000000000000000000000000000822 152.0
HFD1_k127_7134916_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 592.0
HFD1_k127_7134916_1 methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 585.0
HFD1_k127_7134916_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000002652 222.0
HFD1_k127_7134916_3 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000003957 216.0
HFD1_k127_7134916_4 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000002833 150.0
HFD1_k127_7188172_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.828e-263 814.0
HFD1_k127_7188172_1 helicase activity K11927 - 3.6.4.13 0.00000000000000000000000000004406 120.0
HFD1_k127_7189020_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 482.0
HFD1_k127_7189020_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 464.0
HFD1_k127_7189020_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 447.0
HFD1_k127_7189020_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000000002039 103.0
HFD1_k127_7243086_0 PhoQ Sensor - - - 1.046e-277 879.0
HFD1_k127_7243086_1 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 605.0
HFD1_k127_7243086_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 524.0
HFD1_k127_7243086_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 515.0
HFD1_k127_7243086_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 410.0
HFD1_k127_7243086_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 408.0
HFD1_k127_7243086_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 385.0
HFD1_k127_7243086_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 342.0
HFD1_k127_7243086_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 293.0
HFD1_k127_7243086_9 - K19246 - 1.13.11.33 0.00000000000000006994 83.0
HFD1_k127_7251267_0 radical SAM domain protein - - - 0.0 1059.0
HFD1_k127_7251267_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.076e-268 837.0
HFD1_k127_7251267_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 293.0
HFD1_k127_7251267_12 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003432 294.0
HFD1_k127_7251267_13 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006347 257.0
HFD1_k127_7251267_14 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000007292 236.0
HFD1_k127_7251267_15 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002853 235.0
HFD1_k127_7251267_16 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.000000000000000000000000000000000000000000000000000000000000000007175 226.0
HFD1_k127_7251267_17 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000000000001374 225.0
HFD1_k127_7251267_18 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000002775 237.0
HFD1_k127_7251267_19 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.00000000000000000000000000000000000000000000000000000000009131 206.0
HFD1_k127_7251267_2 Major facilitator Superfamily K08218 - - 6.586e-255 796.0
HFD1_k127_7251267_20 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000002113 128.0
HFD1_k127_7251267_22 Methyltransferase small domain - - - 0.00000007335 54.0
HFD1_k127_7251267_3 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 499.0
HFD1_k127_7251267_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 433.0
HFD1_k127_7251267_5 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 421.0
HFD1_k127_7251267_6 electron transfer activity K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 410.0
HFD1_k127_7251267_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 348.0
HFD1_k127_7251267_8 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 331.0
HFD1_k127_7251267_9 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 335.0
HFD1_k127_7300310_0 hydrogen-translocating pyrophosphatase activity K15987 - 3.6.1.1 0.0 1226.0
HFD1_k127_7300310_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1208.0
HFD1_k127_7300310_10 thiosulfate sulfurtransferase activity K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 368.0
HFD1_k127_7300310_11 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003008 256.0
HFD1_k127_7300310_13 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000008754 195.0
HFD1_k127_7300310_14 HemY protein K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000009408 184.0
HFD1_k127_7300310_2 metalloendopeptidase activity K08602 - - 1.151e-278 870.0
HFD1_k127_7300310_20 2 iron, 2 sulfur cluster binding K02192 GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.000000000000000001677 87.0
HFD1_k127_7300310_3 DHH family K07462 - - 2.725e-241 758.0
HFD1_k127_7300310_4 denitrification pathway - - - 1.168e-231 721.0
HFD1_k127_7300310_5 denitrification pathway - - - 1.099e-229 718.0
HFD1_k127_7300310_6 denitrification pathway - - - 9.843e-209 656.0
HFD1_k127_7300310_7 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 514.0
HFD1_k127_7300310_8 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 464.0
HFD1_k127_7312103_0 methyltransferase K16129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 362.0
HFD1_k127_7312103_1 - K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000004221 200.0
HFD1_k127_73303_0 TonB-dependent receptor - - - 0.0 1026.0
HFD1_k127_73303_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 5.518e-307 962.0
HFD1_k127_73303_10 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000249 280.0
HFD1_k127_73303_11 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001814 274.0
HFD1_k127_73303_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002098 253.0
HFD1_k127_73303_13 response to nickel cation K07722 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000007791 215.0
HFD1_k127_73303_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.0000000000000000000000000000000000000000000000000004698 192.0
HFD1_k127_73303_2 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 9.822e-262 819.0
HFD1_k127_73303_20 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000004177 89.0
HFD1_k127_73303_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 1.517e-230 721.0
HFD1_k127_73303_4 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 574.0
HFD1_k127_73303_5 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 569.0
HFD1_k127_73303_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 501.0
HFD1_k127_73303_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 407.0
HFD1_k127_73303_8 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 352.0
HFD1_k127_73303_9 Cytochrome c K03611 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 288.0
HFD1_k127_7337357_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1440.0
HFD1_k127_7337357_1 efflux transmembrane transporter activity K12340 - - 2.127e-232 729.0
HFD1_k127_7337357_11 RNA recognition motif - - - 0.00000000000000000000000000000000000000000003591 164.0
HFD1_k127_7337357_2 Protein of unknown function, DUF255 K06888 - - 5.774e-199 641.0
HFD1_k127_7337357_3 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 570.0
HFD1_k127_7337357_4 helicase activity K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 550.0
HFD1_k127_7337357_5 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 533.0
HFD1_k127_7337357_8 Protein of unknown function (DUF3422) - - - 0.0000000000000000000000000000000000000000000000000000004217 199.0
HFD1_k127_7337357_9 - - - - 0.000000000000000000000000000000000000000000000002934 174.0
HFD1_k127_7363667_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 556.0
HFD1_k127_7363667_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 321.0
HFD1_k127_7363667_2 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000000000008805 211.0
HFD1_k127_7363667_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000002115 128.0
HFD1_k127_7370406_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000001001 139.0
HFD1_k127_7370406_1 to capsid protein Bacteriophage B3 gi 33338632 gb AAQ13956.1 - - - 0.0000000000000000000001674 108.0
HFD1_k127_7370406_2 Mu-like prophage protein gp29 - - - 0.000000000002179 79.0
HFD1_k127_7370406_3 - - - - 0.00000000003808 77.0
HFD1_k127_7370406_4 ubiE/COQ5 methyltransferase family - - - 0.0000000002104 71.0
HFD1_k127_7370406_5 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.000003288 57.0
HFD1_k127_7370406_6 methyltransferase - - - 0.000005975 57.0
HFD1_k127_7370406_8 - - - - 0.0009232 49.0
HFD1_k127_7383971_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2688.0
HFD1_k127_7383971_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 2.163e-303 932.0
HFD1_k127_7383971_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 356.0
HFD1_k127_7383971_12 cysteine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 278.0
HFD1_k127_7383971_13 Domain of unknown function (DUF5069) - - - 0.00000000000000000000000000000000000000000000000000000000000000002156 226.0
HFD1_k127_7383971_14 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.0000000000000000000000000000000000000000000000000000000008447 205.0
HFD1_k127_7383971_15 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000007838 197.0
HFD1_k127_7383971_16 - - - - 0.000000000000000000000000000000000000000000000000455 179.0
HFD1_k127_7383971_17 - - - - 0.000000000000000000000000000000000001862 142.0
HFD1_k127_7383971_18 methyltransferase K03789 - 2.3.1.128 0.000000000000000001589 94.0
HFD1_k127_7383971_2 Periplasmic binding protein - - - 6.783e-234 741.0
HFD1_k127_7383971_20 Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway K15525 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 3.5.1.103 0.00000003066 63.0
HFD1_k127_7383971_3 phosphorelay signal transduction system - - - 3.915e-208 655.0
HFD1_k127_7383971_4 Protein of unknown function (DUF1015) - - - 5.53e-200 632.0
HFD1_k127_7383971_5 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 567.0
HFD1_k127_7383971_6 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 563.0
HFD1_k127_7383971_7 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 510.0
HFD1_k127_7383971_8 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 443.0
HFD1_k127_7383971_9 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 370.0
HFD1_k127_7391468_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1122.0
HFD1_k127_7391468_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.643e-238 744.0
HFD1_k127_7391468_2 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 3.208e-207 655.0
HFD1_k127_7391468_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 552.0
HFD1_k127_7391468_4 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 387.0
HFD1_k127_7391468_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 365.0
HFD1_k127_7391468_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 328.0
HFD1_k127_7391468_7 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 292.0
HFD1_k127_7391468_8 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000004125 230.0
HFD1_k127_7397295_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.161e-225 704.0
HFD1_k127_7397295_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.924e-212 667.0
HFD1_k127_7397295_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 1.799e-209 661.0
HFD1_k127_7397295_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 571.0
HFD1_k127_7397295_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 502.0
HFD1_k127_7397295_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 451.0
HFD1_k127_7397295_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 458.0
HFD1_k127_7397295_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 434.0
HFD1_k127_7402809_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 594.0
HFD1_k127_7402809_1 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 473.0
HFD1_k127_7402809_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates - - - 0.000000000000000000000000000000000000000000000000000000000000000000003147 243.0
HFD1_k127_7402809_3 glucosamine-6-phosphate deaminase activity K01057,K02564 - 3.1.1.31,3.5.99.6 0.00000000000000000000000000000000000000000000000000000000001026 215.0
HFD1_k127_7402809_5 - - - - 0.00000000000000233 77.0
HFD1_k127_7402809_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000005592 58.0
HFD1_k127_7402809_7 Transposase (IS116 IS110 IS902 family) K07486 - - 0.000025 48.0
HFD1_k127_740860_0 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 483.0
HFD1_k127_740860_1 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000001368 211.0
HFD1_k127_740860_2 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000008987 143.0
HFD1_k127_740860_3 peptidase A24A prepilin type IV K02278 - 3.4.23.43 0.000000002629 63.0
HFD1_k127_7417257_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009953 273.0
HFD1_k127_7417257_1 PFAM FecR protein K20276 - - 0.000000000000001455 92.0
HFD1_k127_7437288_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.537e-286 897.0
HFD1_k127_7437288_1 Sigma-54 interaction domain K07714 - - 1.046e-221 696.0
HFD1_k127_7437288_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 457.0
HFD1_k127_7437288_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
HFD1_k127_7437288_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009603 274.0
HFD1_k127_7437288_6 sequence-specific DNA binding - - - 0.000000000000000000000000000000000647 136.0
HFD1_k127_7451010_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1503.0
HFD1_k127_7451010_1 belongs to the aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 0.0 1226.0
HFD1_k127_7451010_10 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 439.0
HFD1_k127_7451010_11 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 431.0
HFD1_k127_7451010_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 438.0
HFD1_k127_7451010_13 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 418.0
HFD1_k127_7451010_14 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 405.0
HFD1_k127_7451010_15 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 345.0
HFD1_k127_7451010_16 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 325.0
HFD1_k127_7451010_17 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 307.0
HFD1_k127_7451010_18 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001734 284.0
HFD1_k127_7451010_19 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001633 256.0
HFD1_k127_7451010_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.441e-267 829.0
HFD1_k127_7451010_20 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000243 250.0
HFD1_k127_7451010_21 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000001425 229.0
HFD1_k127_7451010_22 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000000002866 222.0
HFD1_k127_7451010_23 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000291 214.0
HFD1_k127_7451010_24 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000001097 219.0
HFD1_k127_7451010_25 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000004366 197.0
HFD1_k127_7451010_26 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000000000000000000000001417 166.0
HFD1_k127_7451010_27 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.000000000000000000000000000000000000000000007404 173.0
HFD1_k127_7451010_28 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000000000003561 157.0
HFD1_k127_7451010_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 7.187e-264 815.0
HFD1_k127_7451010_31 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000001962 83.0
HFD1_k127_7451010_32 - - - - 0.00000000000002013 76.0
HFD1_k127_7451010_4 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.395e-234 731.0
HFD1_k127_7451010_5 serine-type endopeptidase activity K04771 - 3.4.21.107 3.407e-225 705.0
HFD1_k127_7451010_6 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.68e-216 685.0
HFD1_k127_7451010_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 529.0
HFD1_k127_7451010_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 504.0
HFD1_k127_7451010_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 498.0
HFD1_k127_7480443_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 2.761e-301 944.0
HFD1_k127_7480443_1 (ABC) transporter K15738 - - 3.027e-279 870.0
HFD1_k127_7480443_10 regulator - - - 0.00000000000000000000000000000000000000000000000000000000000003249 220.0
HFD1_k127_7480443_11 lactoylglutathione lyase activity K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000009276 207.0
HFD1_k127_7480443_12 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000843 201.0
HFD1_k127_7480443_13 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000008399 204.0
HFD1_k127_7480443_14 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000002971 184.0
HFD1_k127_7480443_15 Histidine kinase K17763 - - 0.000000000000000000000000000000002958 151.0
HFD1_k127_7480443_2 symporter activity K03307,K14387 - - 8.898e-208 657.0
HFD1_k127_7480443_3 PFAM 4Fe-4S binding domain - - - 2.153e-200 634.0
HFD1_k127_7480443_4 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 575.0
HFD1_k127_7480443_5 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 571.0
HFD1_k127_7480443_6 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 326.0
HFD1_k127_7480443_7 transmembrane signaling receptor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 312.0
HFD1_k127_7480443_8 Histidine kinase K01120,K07315 - 3.1.3.3,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004907 313.0
HFD1_k127_7480443_9 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001477 229.0
HFD1_k127_7492903_0 Cation transporter/ATPase, N-terminus - - - 0.0 1307.0
HFD1_k127_7492903_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1127.0
HFD1_k127_7492903_2 MacB-like periplasmic core domain K02004 - - 8.275e-199 625.0
HFD1_k127_7492903_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 535.0
HFD1_k127_7492903_4 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 507.0
HFD1_k127_7492903_5 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003111 273.0
HFD1_k127_7492903_6 Universal stress protein - - - 0.0000000000000000000082 100.0
HFD1_k127_7495113_0 ABC transporter K06020 - 3.6.3.25 0.0 1045.0
HFD1_k127_7495113_1 Uncharacterized ACR, YdiU/UPF0061 family K08997 - - 1.596e-240 751.0
HFD1_k127_7495113_10 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000000000000000007773 153.0
HFD1_k127_7495113_12 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000005229 92.0
HFD1_k127_7495113_13 thiolester hydrolase activity K06889,K07000 - - 0.00000000000000927 76.0
HFD1_k127_7495113_14 - - - - 0.00000000001201 69.0
HFD1_k127_7495113_2 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 612.0
HFD1_k127_7495113_3 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 512.0
HFD1_k127_7495113_4 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 357.0
HFD1_k127_7495113_5 Alpha/beta hydrolase family K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 332.0
HFD1_k127_7495113_6 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 323.0
HFD1_k127_7495113_7 metallopeptidase activity K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001214 258.0
HFD1_k127_7495113_8 thiolester hydrolase activity K06889,K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000001162 241.0
HFD1_k127_7495113_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000001383 163.0
HFD1_k127_7505899_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004043 224.0
HFD1_k127_7505899_1 Integrase core domain - - - 0.000000000000002431 76.0
HFD1_k127_7505899_2 Recombinase - - - 0.000000005035 63.0
HFD1_k127_7505899_3 ORF located using Blastx COG2801 - - - 0.00005047 47.0
HFD1_k127_7508719_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1119.0
HFD1_k127_7508719_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 1.464e-216 677.0
HFD1_k127_7508719_10 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 295.0
HFD1_k127_7508719_11 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002035 284.0
HFD1_k127_7508719_12 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006346 241.0
HFD1_k127_7508719_13 serine-type endopeptidase activity K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000001269 235.0
HFD1_k127_7508719_14 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000002909 198.0
HFD1_k127_7508719_16 - - - - 0.000000000000000000000000006666 112.0
HFD1_k127_7508719_19 phosphorelay signal transduction system K02490 - - 0.00000000000000005958 85.0
HFD1_k127_7508719_2 Glycosyl transferase, family 2 K21349 - 2.4.1.268 1.863e-194 616.0
HFD1_k127_7508719_3 B-1 B cell differentiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 576.0
HFD1_k127_7508719_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 511.0
HFD1_k127_7508719_5 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 453.0
HFD1_k127_7508719_6 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 366.0
HFD1_k127_7508719_7 Peptidoglycan-synthase activator LpoB K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
HFD1_k127_7508719_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 301.0
HFD1_k127_7508719_9 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 295.0
HFD1_k127_7511_0 GHKL domain K13598 - 2.7.13.3 0.0 1161.0
HFD1_k127_7511_1 Bacterial regulatory protein, Fis family K13599 - - 1.531e-240 749.0
HFD1_k127_7511_11 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000000000000000004889 152.0
HFD1_k127_7511_12 response regulator - - - 0.00000000009771 70.0
HFD1_k127_7511_14 mechanosensitive ion channel K22044 - - 0.0002845 44.0
HFD1_k127_7511_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 3.884e-211 666.0
HFD1_k127_7511_3 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 523.0
HFD1_k127_7511_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 374.0
HFD1_k127_7511_5 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 356.0
HFD1_k127_7511_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 328.0
HFD1_k127_7511_7 PFAM MscS Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 299.0
HFD1_k127_7511_9 protein trimerization - - - 0.0000000000000000000000000000000000000000000009957 170.0
HFD1_k127_7522681_0 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000006221 225.0
HFD1_k127_7522681_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000001623 52.0
HFD1_k127_7524842_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 1.469e-285 887.0
HFD1_k127_7524842_1 FAD binding domain K00278 - 1.4.3.16 6.571e-266 827.0
HFD1_k127_7524842_10 tRNA processing K06864,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 342.0
HFD1_k127_7524842_11 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007173 267.0
HFD1_k127_7524842_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001188 250.0
HFD1_k127_7524842_13 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000001014 220.0
HFD1_k127_7524842_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000009601 139.0
HFD1_k127_7524842_17 - - - - 0.00000000000000000000000000000000946 132.0
HFD1_k127_7524842_18 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000000000000000000000176 127.0
HFD1_k127_7524842_2 lipopolysaccharide transport K22110 - - 1.342e-231 724.0
HFD1_k127_7524842_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 1.71e-228 714.0
HFD1_k127_7524842_4 ATPase associated with various cellular activities, AAA_5 K02584 - - 3.199e-216 691.0
HFD1_k127_7524842_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 4.711e-206 650.0
HFD1_k127_7524842_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 466.0
HFD1_k127_7524842_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 411.0
HFD1_k127_7524842_8 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01665 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 390.0
HFD1_k127_7524842_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 362.0
HFD1_k127_7553029_0 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 297.0
HFD1_k127_7553029_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000005415 128.0
HFD1_k127_7569488_0 CoA-binding domain protein K09181 - - 8.994e-213 666.0
HFD1_k127_7569488_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000009856 216.0
HFD1_k127_7569488_10 Protein of unknown function (DUF2934) - - - 0.0004734 47.0
HFD1_k127_7569488_11 RNA-binding protein K13091 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0016604,GO:0016607,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0070013 - 0.0005539 47.0
HFD1_k127_7569488_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000001385 214.0
HFD1_k127_7569488_4 - - - - 0.000000000000000000000000000000000000000000004257 173.0
HFD1_k127_7569488_5 periplasmic K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.0000000000000000000119 99.0
HFD1_k127_7569488_6 CsbD-like - - - 0.0000000000000002153 81.0
HFD1_k127_7569488_7 Sulfotransferase family - - - 0.00000000000008934 74.0
HFD1_k127_7569488_8 Protein of unknown function (DUF1328) - - - 0.00000000002926 64.0
HFD1_k127_7569488_9 Translocator protein, LysE family - - - 0.000000002289 66.0
HFD1_k127_7579715_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001255 235.0
HFD1_k127_7579715_1 Universal stress protein - - - 0.0000000000000000000000001511 119.0
HFD1_k127_7579715_2 - - - - 0.000000002566 59.0
HFD1_k127_7602240_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 7.81e-294 906.0
HFD1_k127_7602240_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 6.941e-202 637.0
HFD1_k127_7602240_2 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 321.0
HFD1_k127_7602240_3 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000001136 207.0
HFD1_k127_7602240_4 chlorophyll binding K02051,K03286 - - 0.00000000000000000000000000000000000000000000000000004433 198.0
HFD1_k127_7602240_5 rRNA binding K00185,K02967 - - 0.00000000000000000000000000000000000000000000114 180.0
HFD1_k127_7602240_6 Putative regulatory protein - - - 0.00000000000000000000000006413 110.0
HFD1_k127_7628419_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 1.213e-220 690.0
HFD1_k127_7628419_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 419.0
HFD1_k127_7628419_2 metalloendopeptidase activity K03799,K11749 - - 0.0000000000000000000000000000000008297 140.0
HFD1_k127_7628419_3 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000001004 118.0
HFD1_k127_7628419_4 bacterial-type flagellum-dependent cell motility K02388,K02396 - - 0.00000000000000000000000003935 126.0
HFD1_k127_7628419_5 PA14 domain - - - 0.0009893 52.0
HFD1_k127_7662196_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.115e-275 857.0
HFD1_k127_7662196_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.254e-252 782.0
HFD1_k127_7662196_10 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 411.0
HFD1_k127_7662196_11 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 398.0
HFD1_k127_7662196_12 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 384.0
HFD1_k127_7662196_13 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 349.0
HFD1_k127_7662196_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 345.0
HFD1_k127_7662196_15 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 327.0
HFD1_k127_7662196_16 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 306.0
HFD1_k127_7662196_17 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 299.0
HFD1_k127_7662196_18 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 292.0
HFD1_k127_7662196_19 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001309 274.0
HFD1_k127_7662196_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 2.829e-235 736.0
HFD1_k127_7662196_20 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005235 270.0
HFD1_k127_7662196_21 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006396 253.0
HFD1_k127_7662196_22 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006142 255.0
HFD1_k127_7662196_23 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005076 241.0
HFD1_k127_7662196_24 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001058 234.0
HFD1_k127_7662196_25 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000004022 222.0
HFD1_k127_7662196_26 Protein conserved in bacteria K11719 - - 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
HFD1_k127_7662196_27 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003286 211.0
HFD1_k127_7662196_28 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000005123 201.0
HFD1_k127_7662196_29 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000765 198.0
HFD1_k127_7662196_3 Secretin and TonB N terminus short domain K02666 - - 3.795e-219 703.0
HFD1_k127_7662196_30 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000001502 192.0
HFD1_k127_7662196_31 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000004043 191.0
HFD1_k127_7662196_32 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000000000000000000000000000000000009621 196.0
HFD1_k127_7662196_33 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001774 188.0
HFD1_k127_7662196_34 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000000001078 169.0
HFD1_k127_7662196_35 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000002367 169.0
HFD1_k127_7662196_36 OstA-like protein K09774 - - 0.0000000000000000000000000000000000000000001739 166.0
HFD1_k127_7662196_37 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000009552 156.0
HFD1_k127_7662196_38 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000003734 143.0
HFD1_k127_7662196_39 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000002367 147.0
HFD1_k127_7662196_4 ANTAR - - - 2.671e-213 668.0
HFD1_k127_7662196_40 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000006106 138.0
HFD1_k127_7662196_41 30S ribosomal protein S14 K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002261 114.0
HFD1_k127_7662196_42 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001844 87.0
HFD1_k127_7662196_43 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000887 73.0
HFD1_k127_7662196_44 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001187 70.0
HFD1_k127_7662196_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 569.0
HFD1_k127_7662196_6 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 514.0
HFD1_k127_7662196_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 477.0
HFD1_k127_7662196_8 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 464.0
HFD1_k127_7662196_9 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 451.0
HFD1_k127_7665914_0 nuclease - - - 0.00000000000000000000000000000000368 134.0
HFD1_k127_7665914_1 - - - - 0.000000000000008844 79.0
HFD1_k127_7665914_2 - - - - 0.000000000005048 73.0
HFD1_k127_7665914_3 - - - - 0.0000004521 61.0
HFD1_k127_7739006_0 DNA topoisomerase II activity K03167 - 5.99.1.3 3.887e-314 974.0
HFD1_k127_7739006_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 7.763e-231 721.0
HFD1_k127_7739006_10 Met-10+ like-protein - - - 0.00000000000000000000000000000000000000000000005049 181.0
HFD1_k127_7739006_11 diguanylate cyclase - - - 0.000000000000000000000000000000000000008881 166.0
HFD1_k127_7739006_12 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000000005231 140.0
HFD1_k127_7739006_14 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000001106 113.0
HFD1_k127_7739006_16 GYD domain - - - 0.0000000000103 69.0
HFD1_k127_7739006_17 - - - - 0.00002499 52.0
HFD1_k127_7739006_2 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.689e-222 691.0
HFD1_k127_7739006_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 556.0
HFD1_k127_7739006_4 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 330.0
HFD1_k127_7739006_5 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009334 271.0
HFD1_k127_7739006_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002983 231.0
HFD1_k127_7739006_7 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000000000000000000000000000000001428 199.0
HFD1_k127_7739006_8 CHAD - - - 0.0000000000000000000000000000000000000000000000000000004757 212.0
HFD1_k127_7754957_0 Type II/IV secretion system protein K02454,K02652 - - 0.0 1219.0
HFD1_k127_7754957_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.559e-280 870.0
HFD1_k127_7754957_10 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 428.0
HFD1_k127_7754957_11 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 402.0
HFD1_k127_7754957_12 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 401.0
HFD1_k127_7754957_13 tRNA (guanine(37)-N(1))-methyltransferase activity K01091,K01633,K15429 - 1.13.11.81,2.1.1.228,3.1.3.18,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 398.0
HFD1_k127_7754957_14 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 352.0
HFD1_k127_7754957_15 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 317.0
HFD1_k127_7754957_16 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 316.0
HFD1_k127_7754957_17 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003721 279.0
HFD1_k127_7754957_18 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003746 281.0
HFD1_k127_7754957_19 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005076 263.0
HFD1_k127_7754957_2 Putative modulator of DNA gyrase K03568 - - 2.31e-255 793.0
HFD1_k127_7754957_20 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002319 258.0
HFD1_k127_7754957_21 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000005892 258.0
HFD1_k127_7754957_22 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000002845 257.0
HFD1_k127_7754957_24 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000001712 207.0
HFD1_k127_7754957_25 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000000000001506 206.0
HFD1_k127_7754957_26 Cupin domain - - - 0.0000000000000000000000000000000000000000000000001172 179.0
HFD1_k127_7754957_28 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000105 149.0
HFD1_k127_7754957_29 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000001783 156.0
HFD1_k127_7754957_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.344e-202 645.0
HFD1_k127_7754957_31 Mo-molybdopterin cofactor metabolic process K03636 - - 0.00000000000000000000000000000072 131.0
HFD1_k127_7754957_34 domain, Protein K18491 - - 0.00000000000000000000001548 108.0
HFD1_k127_7754957_35 peptidase - - - 0.000000000000000003466 89.0
HFD1_k127_7754957_38 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000756 66.0
HFD1_k127_7754957_4 Putative modulator of DNA gyrase K03592 - - 2.657e-201 637.0
HFD1_k127_7754957_41 RNA binding motif single stranded interacting protein - GO:0000003,GO:0002347,GO:0002357,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006417,GO:0006950,GO:0006952,GO:0007275,GO:0007399,GO:0007552,GO:0007610,GO:0007617,GO:0007618,GO:0007619,GO:0007626,GO:0008050,GO:0008143,GO:0008150,GO:0008187,GO:0008266,GO:0008344,GO:0009605,GO:0009607,GO:0009628,GO:0009629,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010648,GO:0016322,GO:0017091,GO:0017148,GO:0019098,GO:0019222,GO:0019953,GO:0021700,GO:0022008,GO:0022414,GO:0023051,GO:0023057,GO:0030111,GO:0030154,GO:0030178,GO:0030182,GO:0030534,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0033554,GO:0034248,GO:0034249,GO:0034250,GO:0034976,GO:0035925,GO:0040011,GO:0042330,GO:0042332,GO:0042551,GO:0044424,GO:0044464,GO:0044703,GO:0045727,GO:0048468,GO:0048469,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048609,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051704,GO:0051716,GO:0060180,GO:0060255,GO:0060828,GO:0065007,GO:0070717,GO:0071695,GO:0080090,GO:0090090,GO:0097159,GO:1901363,GO:2000112,GO:2000113 - 0.00000002635 58.0
HFD1_k127_7754957_43 - - - - 0.0001479 46.0
HFD1_k127_7754957_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 614.0
HFD1_k127_7754957_7 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 567.0
HFD1_k127_7754957_8 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 567.0
HFD1_k127_7754957_9 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 442.0
HFD1_k127_7779655_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1529.0
HFD1_k127_7779655_1 silver ion transport K15726 - - 0.0 1440.0
HFD1_k127_7779655_10 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 498.0
HFD1_k127_7779655_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 464.0
HFD1_k127_7779655_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 454.0
HFD1_k127_7779655_13 calcium:proton antiporter activity K07300 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 446.0
HFD1_k127_7779655_14 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 425.0
HFD1_k127_7779655_15 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 410.0
HFD1_k127_7779655_16 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 377.0
HFD1_k127_7779655_17 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 337.0
HFD1_k127_7779655_18 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 326.0
HFD1_k127_7779655_19 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 305.0
HFD1_k127_7779655_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1342.0
HFD1_k127_7779655_20 FMN binding K19339,K19343 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 297.0
HFD1_k127_7779655_21 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 291.0
HFD1_k127_7779655_24 response regulator K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006707 280.0
HFD1_k127_7779655_25 photosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007852 276.0
HFD1_k127_7779655_26 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008556 288.0
HFD1_k127_7779655_28 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006335 265.0
HFD1_k127_7779655_29 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000002809 272.0
HFD1_k127_7779655_3 thiamine transport K02011 - - 7.2e-233 731.0
HFD1_k127_7779655_30 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000005437 238.0
HFD1_k127_7779655_31 bacteriocin transport K03561,K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000002864 233.0
HFD1_k127_7779655_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001936 223.0
HFD1_k127_7779655_33 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000002417 182.0
HFD1_k127_7779655_34 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000172 181.0
HFD1_k127_7779655_35 GGDEF domain - - - 0.00000000000000000000000000000000000000000000003272 172.0
HFD1_k127_7779655_38 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.00000000000000000000000000000004898 138.0
HFD1_k127_7779655_4 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 570.0
HFD1_k127_7779655_40 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000005901 112.0
HFD1_k127_7779655_41 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000007083 88.0
HFD1_k127_7779655_42 COG0784 FOG CheY-like receiver K07315 - 3.1.3.3 0.00000000000003446 78.0
HFD1_k127_7779655_43 PFAM YHS domain - - - 0.000000000000148 73.0
HFD1_k127_7779655_44 - - - - 0.000002807 51.0
HFD1_k127_7779655_5 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 569.0
HFD1_k127_7779655_6 ATPase activity K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 533.0
HFD1_k127_7779655_7 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 530.0
HFD1_k127_7779655_8 iron ion homeostasis K02012 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 518.0
HFD1_k127_7779655_9 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 508.0
HFD1_k127_7808856_0 domain, Protein - - - 0.00000000000000000000000000000000000000000006646 181.0
HFD1_k127_7808856_1 domain, Protein - - - 0.0000000000000008973 82.0
HFD1_k127_7856392_0 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 4.042e-253 793.0
HFD1_k127_7856392_1 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 386.0
HFD1_k127_7856392_2 Cytochrome c K03611 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006456 280.0
HFD1_k127_7856392_3 PFAM membrane protein of K08972 - - 0.000000000000000007826 89.0
HFD1_k127_792655_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 527.0
HFD1_k127_792655_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 514.0
HFD1_k127_792655_10 - K14588 - - 0.000000000000000000000000000000000000000006871 158.0
HFD1_k127_792655_12 Domain of unknown function (DUF4382) - - - 0.00000000000000000002316 93.0
HFD1_k127_792655_14 regulatory protein, FmdB family - - - 0.0009344 46.0
HFD1_k127_792655_2 Response regulator, receiver K20973 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 492.0
HFD1_k127_792655_3 Squalene/phytoene synthase K00801 - 2.5.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 459.0
HFD1_k127_792655_4 transmembrane transport K02532,K05820,K08167,K08218,K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 437.0
HFD1_k127_792655_5 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 302.0
HFD1_k127_792655_7 response regulator, receiver K03413,K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 284.0
HFD1_k127_792655_8 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000001741 204.0
HFD1_k127_792655_9 - - - - 0.000000000000000000000000000000000000000000000000002924 193.0
HFD1_k127_7964824_0 sulfate adenylyltransferase (ATP) activity K00860,K00955,K00956 - 2.7.1.25,2.7.7.4 4.987e-311 961.0
HFD1_k127_7964824_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 2.372e-200 633.0
HFD1_k127_7964824_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000004242 243.0
HFD1_k127_7964824_12 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000007166 107.0
HFD1_k127_7964824_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 570.0
HFD1_k127_7964824_3 protein tyrosine kinase activity K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 554.0
HFD1_k127_7964824_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 541.0
HFD1_k127_7964824_5 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 510.0
HFD1_k127_7964824_6 Glycosyl transferase family, a/b domain K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 440.0
HFD1_k127_7964824_7 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 426.0
HFD1_k127_7964824_8 Proto-chlorophyllide reductase 57 kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 426.0
HFD1_k127_7964824_9 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001755 263.0
HFD1_k127_7998534_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 598.0
HFD1_k127_7998534_1 PFAM metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000004353 190.0
HFD1_k127_7998534_3 nuclear chromosome segregation K02666,K03497,K19622 - - 0.00000000000000000003636 100.0
HFD1_k127_865644_0 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 401.0
HFD1_k127_865644_1 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 312.0
HFD1_k127_865644_2 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009936 277.0
HFD1_k127_865644_3 thiosulfate sulfurtransferase activity K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000000000000000000000000000000000000000000000000000007633 199.0
HFD1_k127_865644_4 Small metal-binding protein - - - 0.0000000000000000002296 93.0
HFD1_k127_865644_5 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00002502 56.0
HFD1_k127_898098_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1030.0
HFD1_k127_898098_1 Alpha-amylase domain K01187 - 3.2.1.20 0.000000000000000000434 91.0
HFD1_k127_955505_0 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 3.568e-266 833.0
HFD1_k127_955505_1 Glycogen debranching enzyme N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 401.0
HFD1_k127_9653_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 414.0
HFD1_k127_9653_1 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HFD1_k127_9653_2 biosynthesis glycosyltransferase K12984 - - 0.00000000000000000000000000000000000000000000000000000000001971 216.0
HFD1_k127_9653_3 Glycosyl transferase, family 2 - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000002165 137.0
HFD1_k127_994055_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.565e-293 906.0
HFD1_k127_994055_1 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000001083 191.0