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Overview

ID MAG01621
Name HFD1_bin.30
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order Pyrinomonadales
Family Pyrinomonadaceae
Genus PSRF01
Species
Assembly information
Completeness (%) 87.67
Contamination (%) 2.96
GC content (%) 56.0
N50 (bp) 16,848
Genome size (bp) 4,760,645

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3752

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1002747_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 436.0
HFD1_k127_1002747_1 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 428.0
HFD1_k127_1002747_10 chlorophyll binding - - - 0.000000000000000000000000000000000001698 151.0
HFD1_k127_1002747_11 Aspartyl protease - - - 0.00000000000000000000000000000000005567 140.0
HFD1_k127_1002747_12 Thioesterase superfamily K10806 - - 0.00000000000000000000000000001461 122.0
HFD1_k127_1002747_13 - - - - 0.000000000000000000000001032 107.0
HFD1_k127_1002747_14 PFAM von Willebrand factor type A - - - 0.000000000000000000001276 108.0
HFD1_k127_1002747_15 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000007325 99.0
HFD1_k127_1002747_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 406.0
HFD1_k127_1002747_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 351.0
HFD1_k127_1002747_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 349.0
HFD1_k127_1002747_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006867 263.0
HFD1_k127_1002747_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000006348 207.0
HFD1_k127_1002747_7 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000005991 189.0
HFD1_k127_1002747_8 hydrolase of the alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000003917 185.0
HFD1_k127_1002747_9 photosynthesis - - - 0.000000000000000000000000000000000000000001905 162.0
HFD1_k127_1004614_0 iron-nicotianamine transmembrane transporter activity - - - 9.19e-286 901.0
HFD1_k127_1004614_1 Zinc carboxypeptidase - - - 1.373e-220 712.0
HFD1_k127_1004614_10 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
HFD1_k127_1004614_11 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000003938 249.0
HFD1_k127_1004614_12 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000002209 197.0
HFD1_k127_1004614_13 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.000000000000000000000000000000000000000009012 155.0
HFD1_k127_1004614_14 CHRD domain - - - 0.000000000000000000000000000000000008741 141.0
HFD1_k127_1004614_15 YHS domain K06966 - 3.2.2.10 0.00000000000000000000000000000001393 134.0
HFD1_k127_1004614_16 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000007287 115.0
HFD1_k127_1004614_17 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000000005479 109.0
HFD1_k127_1004614_18 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000004935 109.0
HFD1_k127_1004614_19 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000003423 73.0
HFD1_k127_1004614_2 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 1.185e-199 638.0
HFD1_k127_1004614_20 Domain of unknown function (DUF1844) - - - 0.000000000001619 75.0
HFD1_k127_1004614_21 membrane - - - 0.0001334 52.0
HFD1_k127_1004614_3 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 571.0
HFD1_k127_1004614_4 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 413.0
HFD1_k127_1004614_5 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 394.0
HFD1_k127_1004614_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 364.0
HFD1_k127_1004614_7 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 351.0
HFD1_k127_1004614_8 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007439 286.0
HFD1_k127_1004614_9 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000001177 259.0
HFD1_k127_1024272_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 6.286e-205 653.0
HFD1_k127_1024272_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 610.0
HFD1_k127_1024272_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001176 244.0
HFD1_k127_1024272_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000003293 193.0
HFD1_k127_1024272_12 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000005393 176.0
HFD1_k127_1024272_13 - - - - 0.00000000000000000000000000000000000000000000001122 174.0
HFD1_k127_1024272_14 arogenate dehydratase activity K05359,K20102 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009637,GO:0009642,GO:0009645,GO:0009987,GO:0010244,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047769,GO:0050896,GO:0071704,GO:0080167,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,4.2.1.91 0.0000000000000000000000000000000000000003232 158.0
HFD1_k127_1024272_15 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000006809 135.0
HFD1_k127_1024272_16 - - - - 0.00000000000000000000000000000004631 139.0
HFD1_k127_1024272_17 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000006971 122.0
HFD1_k127_1024272_18 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000729 102.0
HFD1_k127_1024272_19 PFAM Chorismate mutase, type II - - - 0.0000000000008661 71.0
HFD1_k127_1024272_2 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 591.0
HFD1_k127_1024272_3 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 460.0
HFD1_k127_1024272_4 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 417.0
HFD1_k127_1024272_5 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 406.0
HFD1_k127_1024272_6 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 404.0
HFD1_k127_1024272_7 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 338.0
HFD1_k127_1024272_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 308.0
HFD1_k127_1024272_9 PFAM monooxygenase FAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007314 262.0
HFD1_k127_1069972_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 3.119e-287 903.0
HFD1_k127_1069972_1 repeat protein - - - 3.792e-280 877.0
HFD1_k127_1069972_10 - - - - 0.0000000000000000000000000000000000000000000002612 171.0
HFD1_k127_1069972_11 BON domain - - - 0.00000000000000000000000000000000000000000001068 170.0
HFD1_k127_1069972_12 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000004376 146.0
HFD1_k127_1069972_13 Universal stress protein family - - - 0.00000000000000000000000000003918 129.0
HFD1_k127_1069972_14 AMP binding - - - 0.0000000000000000001398 100.0
HFD1_k127_1069972_16 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000007768 91.0
HFD1_k127_1069972_17 Universal stress protein family - - - 0.0000000001862 72.0
HFD1_k127_1069972_18 Family of unknown function (DUF5335) - - - 0.0000002415 57.0
HFD1_k127_1069972_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 2.787e-279 879.0
HFD1_k127_1069972_3 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 558.0
HFD1_k127_1069972_4 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 415.0
HFD1_k127_1069972_5 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 351.0
HFD1_k127_1069972_6 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006273 289.0
HFD1_k127_1069972_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000491 258.0
HFD1_k127_1069972_8 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004464 251.0
HFD1_k127_1069972_9 NnrS protein - - - 0.000000000000000000000000000000000000000000000000000000000000001647 235.0
HFD1_k127_1076380_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 469.0
HFD1_k127_1076380_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000001469 224.0
HFD1_k127_1076380_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.000000000004009 78.0
HFD1_k127_1085242_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 359.0
HFD1_k127_1085242_1 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 291.0
HFD1_k127_1085242_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 286.0
HFD1_k127_1085242_3 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000004655 217.0
HFD1_k127_1085242_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000001029 180.0
HFD1_k127_1085242_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000002276 142.0
HFD1_k127_1089366_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 559.0
HFD1_k127_1089366_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 384.0
HFD1_k127_1089366_10 IMP dehydrogenase activity - - - 0.00000000000000000000001605 109.0
HFD1_k127_1089366_11 - - - - 0.00000000000000000008247 101.0
HFD1_k127_1089366_12 ATPase family associated with various cellular activities (AAA) K10943 - - 0.0000000000000000009509 93.0
HFD1_k127_1089366_13 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000000000000005484 96.0
HFD1_k127_1089366_14 acetyltransferase K06976 - - 0.0000000000000001856 91.0
HFD1_k127_1089366_15 COG0500 SAM-dependent methyltransferases - - - 0.00000000001892 72.0
HFD1_k127_1089366_16 Tetratricopeptide repeat K09527 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0030544,GO:0031072,GO:0051084,GO:0051085,GO:0061077 - 0.00000000002712 73.0
HFD1_k127_1089366_17 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000009774 59.0
HFD1_k127_1089366_2 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 379.0
HFD1_k127_1089366_20 metallopeptidase activity K01387 - 3.4.24.3 0.00008979 56.0
HFD1_k127_1089366_21 Bacterial DNA-binding protein K03530 - - 0.00009016 44.0
HFD1_k127_1089366_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 324.0
HFD1_k127_1089366_4 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 312.0
HFD1_k127_1089366_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
HFD1_k127_1089366_6 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002618 245.0
HFD1_k127_1089366_7 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000008244 161.0
HFD1_k127_1089366_8 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000001751 127.0
HFD1_k127_1089366_9 - - - - 0.000000000000000000000000007715 122.0
HFD1_k127_1115080_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 497.0
HFD1_k127_1115080_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 310.0
HFD1_k127_1115080_10 Transglycosylase SLT domain K08309 - - 0.00000007233 58.0
HFD1_k127_1115080_11 PEP-CTERM motif - - - 0.0000001269 61.0
HFD1_k127_1115080_2 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000000000000003106 199.0
HFD1_k127_1115080_3 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000002289 175.0
HFD1_k127_1115080_4 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000008074 147.0
HFD1_k127_1115080_5 YoeB-like toxin of bacterial type II toxin-antitoxin system K19158 - - 0.00000000000000000000000000000001255 130.0
HFD1_k127_1115080_6 - - - - 0.00000000000000000000000000002564 123.0
HFD1_k127_1115080_7 PIN domain - - - 0.000000000000000000000002258 109.0
HFD1_k127_1115080_8 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.00000000000000000000005354 102.0
HFD1_k127_1115080_9 Aspartyl protease - - - 0.00000003694 66.0
HFD1_k127_1128783_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 8.389e-203 648.0
HFD1_k127_1128783_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 549.0
HFD1_k127_1128783_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 453.0
HFD1_k127_1128783_3 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000001097 235.0
HFD1_k127_1154081_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 509.0
HFD1_k127_1154081_1 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 467.0
HFD1_k127_1154081_10 - - - - 0.000000000000000000002607 100.0
HFD1_k127_1154081_11 - - - - 0.0000001009 59.0
HFD1_k127_1154081_13 methyltransferase - - - 0.0001341 45.0
HFD1_k127_1154081_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 458.0
HFD1_k127_1154081_3 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 456.0
HFD1_k127_1154081_4 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 396.0
HFD1_k127_1154081_5 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 344.0
HFD1_k127_1154081_6 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 331.0
HFD1_k127_1154081_7 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000005361 140.0
HFD1_k127_1154081_8 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000004701 135.0
HFD1_k127_1154081_9 - - - - 0.0000000000000000000005874 104.0
HFD1_k127_1180712_0 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 423.0
HFD1_k127_1180712_1 Serine threonine protein kinase involved in cell cycle control - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 380.0
HFD1_k127_1180712_10 Bacterial virulence protein (VirJ) - - - 0.000703 51.0
HFD1_k127_1180712_2 Ami_2 - - - 0.00000000000000000000000000000000000000000000000000000000000000006643 226.0
HFD1_k127_1180712_3 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K14205 - 2.3.2.3 0.00000000000000000000000000000000000000000000000000000000007339 218.0
HFD1_k127_1180712_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000434 195.0
HFD1_k127_1180712_5 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000000000000000004132 170.0
HFD1_k127_1180712_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000002323 166.0
HFD1_k127_1180712_7 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000002711 134.0
HFD1_k127_1180712_8 Uncharacterised conserved protein (DUF2156) - - - 0.00000000002508 74.0
HFD1_k127_1180712_9 membrane-associated protein - - - 0.0000005659 60.0
HFD1_k127_118332_0 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 331.0
HFD1_k127_118332_1 Protein of unknown function with PCYCGC motif - - - 0.00000000000000002335 88.0
HFD1_k127_118332_2 exo-alpha-(2->6)-sialidase activity - - - 0.00000000006756 70.0
HFD1_k127_118332_3 Copper binding periplasmic protein CusF - - - 0.00000006682 60.0
HFD1_k127_1183594_0 WD domain, G-beta repeat - - - 2.738e-226 747.0
HFD1_k127_1183594_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 515.0
HFD1_k127_1183594_10 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007592 235.0
HFD1_k127_1183594_11 Extracellular nuclease - - - 0.0000000000000000000000000000000000000000001451 185.0
HFD1_k127_1183594_12 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000007399 137.0
HFD1_k127_1183594_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000008027 114.0
HFD1_k127_1183594_14 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000001291 119.0
HFD1_k127_1183594_15 - - - - 0.0000000000000000005756 94.0
HFD1_k127_1183594_16 - - - - 0.00000000000000001447 91.0
HFD1_k127_1183594_17 - - - - 0.0000000000000005709 85.0
HFD1_k127_1183594_18 Protein of unknown function (DUF3761) - - - 0.0000000003584 64.0
HFD1_k127_1183594_19 ig-like, plexins, transcription factors - - - 0.0000000003955 75.0
HFD1_k127_1183594_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 521.0
HFD1_k127_1183594_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 426.0
HFD1_k127_1183594_4 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 396.0
HFD1_k127_1183594_5 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 345.0
HFD1_k127_1183594_6 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 352.0
HFD1_k127_1183594_7 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 311.0
HFD1_k127_1183594_8 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002409 265.0
HFD1_k127_1183594_9 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000001723 249.0
HFD1_k127_1192277_0 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000005818 187.0
HFD1_k127_1192277_1 Protein tyrosine kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000002461 121.0
HFD1_k127_1192277_2 Belongs to the SEDS family - - - 0.00000000002165 66.0
HFD1_k127_1271867_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.809e-289 914.0
HFD1_k127_1271867_1 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000202 248.0
HFD1_k127_1271867_2 methyltransferase - - - 0.00000000000000000006675 100.0
HFD1_k127_1273710_0 GTP-binding protein TypA K06207 - - 4.683e-261 816.0
HFD1_k127_1273710_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000007383 90.0
HFD1_k127_1275581_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 507.0
HFD1_k127_1275581_1 Vault protein inter-alpha-trypsin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 450.0
HFD1_k127_1275581_10 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000001035 135.0
HFD1_k127_1275581_11 Xanthine and CO dehydrogenases maturation factor XdhC CoxF K07402 - - 0.00000000000000000000001755 104.0
HFD1_k127_1275581_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 317.0
HFD1_k127_1275581_3 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 304.0
HFD1_k127_1275581_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000006884 222.0
HFD1_k127_1275581_5 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000008727 194.0
HFD1_k127_1275581_6 - - - - 0.00000000000000000000000000000000000000000000007894 177.0
HFD1_k127_1275581_7 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000163 167.0
HFD1_k127_1275581_8 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000001889 157.0
HFD1_k127_1275581_9 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000009155 149.0
HFD1_k127_1292674_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 347.0
HFD1_k127_1292674_1 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004564 305.0
HFD1_k127_1292674_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000002613 188.0
HFD1_k127_1317814_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 632.0
HFD1_k127_1317814_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 389.0
HFD1_k127_1317814_2 PFAM peptidase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 326.0
HFD1_k127_1317814_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 321.0
HFD1_k127_1317814_4 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000003724 253.0
HFD1_k127_1317814_5 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000593 192.0
HFD1_k127_1317814_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000004502 169.0
HFD1_k127_1317814_7 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000007048 115.0
HFD1_k127_1317814_8 - - - - 0.00002068 48.0
HFD1_k127_1344734_0 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 1.128e-259 814.0
HFD1_k127_1344734_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 629.0
HFD1_k127_1344734_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 330.0
HFD1_k127_1344734_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000002193 237.0
HFD1_k127_1344734_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000004342 218.0
HFD1_k127_1344734_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000006403 206.0
HFD1_k127_1344734_6 - - - - 0.00000000000000000000000000000000000004817 159.0
HFD1_k127_1344734_7 DinB family - - - 0.000000000000000001247 93.0
HFD1_k127_1393542_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 506.0
HFD1_k127_1393542_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 473.0
HFD1_k127_1393542_10 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000005455 182.0
HFD1_k127_1393542_11 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000002687 176.0
HFD1_k127_1393542_12 PFAM Iron permease FTR1 - - - 0.00000000000000000007369 100.0
HFD1_k127_1393542_13 Protein of unknown function (DUF1176) - - - 0.00000000000001019 84.0
HFD1_k127_1393542_14 Protein conserved in bacteria K09914 - - 0.000000000009467 75.0
HFD1_k127_1393542_15 Protein of unknown function (DUF3108) - - - 0.0000005288 62.0
HFD1_k127_1393542_16 translation initiation factor activity K08086,K20541 - - 0.000001221 61.0
HFD1_k127_1393542_17 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.000488 51.0
HFD1_k127_1393542_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 416.0
HFD1_k127_1393542_3 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 420.0
HFD1_k127_1393542_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 399.0
HFD1_k127_1393542_5 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 332.0
HFD1_k127_1393542_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 312.0
HFD1_k127_1393542_7 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000106 282.0
HFD1_k127_1393542_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000002819 228.0
HFD1_k127_1393542_9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000001453 207.0
HFD1_k127_1406089_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1026.0
HFD1_k127_1406089_1 imidazolonepropionase activity K00466 - 1.13.12.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 540.0
HFD1_k127_1406089_10 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000002957 117.0
HFD1_k127_1406089_11 PFAM response regulator receiver K07657 - - 0.0000000000000000000003083 100.0
HFD1_k127_1406089_12 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001119 97.0
HFD1_k127_1406089_13 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000001896 93.0
HFD1_k127_1406089_14 KH domain K06960 - - 0.000000000000000173 81.0
HFD1_k127_1406089_15 nuclear chromosome segregation - - - 0.000008244 55.0
HFD1_k127_1406089_2 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 406.0
HFD1_k127_1406089_3 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 406.0
HFD1_k127_1406089_4 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009752 279.0
HFD1_k127_1406089_5 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004866 270.0
HFD1_k127_1406089_6 DEAD DEAH box helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001271 262.0
HFD1_k127_1406089_7 DSHCT - - - 0.0000000000000000000000000000000000000000000000000000000000000000007261 250.0
HFD1_k127_1406089_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000001265 156.0
HFD1_k127_1406089_9 - - - - 0.000000000000000000000000000000001784 144.0
HFD1_k127_1435466_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 410.0
HFD1_k127_1435466_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004616 287.0
HFD1_k127_1435466_2 Subtilase family K14645 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000001844 215.0
HFD1_k127_1435466_3 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000005066 168.0
HFD1_k127_1435466_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.000000000000000000000000000000000000000002703 164.0
HFD1_k127_1435466_5 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000002323 152.0
HFD1_k127_1468225_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 472.0
HFD1_k127_1468225_1 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 415.0
HFD1_k127_1468225_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000002704 134.0
HFD1_k127_1468225_3 regulation of RNA biosynthetic process - - - 0.00000000000000000003706 96.0
HFD1_k127_1489564_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 548.0
HFD1_k127_1489564_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000688 182.0
HFD1_k127_1489564_2 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000004545 134.0
HFD1_k127_1489564_3 shape-determining protein MreD K03571 - - 0.00005983 53.0
HFD1_k127_1489564_4 FecR protein - - - 0.0007098 51.0
HFD1_k127_1492043_0 iron-sulfur cluster biosynthesis transcriptional regulator SufR K09012 - - 0.00000000000000000000000000000000000000000000000000000000000000000003796 237.0
HFD1_k127_1492043_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000008852 242.0
HFD1_k127_1492043_2 Peptidase M56 - - - 0.000000000000000000000002159 115.0
HFD1_k127_1492043_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000003474 55.0
HFD1_k127_1492043_4 KR domain - - - 0.00000004378 56.0
HFD1_k127_1587713_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 4.834e-205 650.0
HFD1_k127_160350_0 ABC transporter transmembrane region K11085 - - 3.139e-236 744.0
HFD1_k127_160350_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 587.0
HFD1_k127_160350_10 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001215 280.0
HFD1_k127_160350_11 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
HFD1_k127_160350_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000000000000000001325 204.0
HFD1_k127_160350_13 - - - - 0.0000000000000000000000000000000000000000000000000009322 197.0
HFD1_k127_160350_14 PFAM NAD-dependent epimerase dehydratase K01709,K01710 - 4.2.1.45,4.2.1.46 0.000000000000000000000000000000000000000000000000009451 183.0
HFD1_k127_160350_15 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000001812 207.0
HFD1_k127_160350_16 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000005274 114.0
HFD1_k127_160350_17 Protein of unknown function DUF115 - - - 0.00000000000000000000001504 111.0
HFD1_k127_160350_18 Sensory domain in DIguanylate Cyclases and Two-component system - - - 0.00000000000003331 80.0
HFD1_k127_160350_19 von Willebrand factor, type A - - - 0.00000006057 65.0
HFD1_k127_160350_2 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 473.0
HFD1_k127_160350_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 438.0
HFD1_k127_160350_4 Phosphate acetyl/butaryl transferase K00625,K13788 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 340.0
HFD1_k127_160350_5 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 317.0
HFD1_k127_160350_6 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 312.0
HFD1_k127_160350_7 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
HFD1_k127_160350_8 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005013 261.0
HFD1_k127_160350_9 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000001925 259.0
HFD1_k127_1645248_0 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 535.0
HFD1_k127_1645248_1 PFAM amino acid permease-associated region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 400.0
HFD1_k127_1645248_10 Membrane - GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000004323 87.0
HFD1_k127_1645248_2 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004202 286.0
HFD1_k127_1645248_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008205 268.0
HFD1_k127_1645248_4 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000008035 222.0
HFD1_k127_1645248_5 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000001304 160.0
HFD1_k127_1645248_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000009619 112.0
HFD1_k127_1645248_7 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000004019 119.0
HFD1_k127_1645248_8 PFAM UspA domain protein K06149 - - 0.00000000000000000000000008331 113.0
HFD1_k127_1645248_9 Belongs to the Nudix hydrolase family - - - 0.0000000000000000232 87.0
HFD1_k127_1648592_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 501.0
HFD1_k127_1648592_1 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 372.0
HFD1_k127_1648592_10 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000002562 124.0
HFD1_k127_1648592_11 NfeD-like C-terminal, partner-binding - - - 0.00000000000000001084 89.0
HFD1_k127_1648592_12 Belongs to the peptidase M16 family - - - 0.00000000000001075 87.0
HFD1_k127_1648592_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 343.0
HFD1_k127_1648592_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 318.0
HFD1_k127_1648592_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 309.0
HFD1_k127_1648592_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000004113 245.0
HFD1_k127_1648592_6 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000001785 229.0
HFD1_k127_1648592_7 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000001173 209.0
HFD1_k127_1648592_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000004905 157.0
HFD1_k127_1648592_9 Transport permease protein K01992 - - 0.00000000000000000000000000000000000009616 153.0
HFD1_k127_1654172_0 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 3.349e-266 838.0
HFD1_k127_1654172_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 2.321e-264 836.0
HFD1_k127_1654172_2 Fibronectin type III-like domain K05349 - 3.2.1.21 1.143e-226 718.0
HFD1_k127_1654172_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 1.898e-225 703.0
HFD1_k127_1654172_4 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 615.0
HFD1_k127_1654172_5 xylose isomerase activity K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 571.0
HFD1_k127_1654172_6 glucuronate isomerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 463.0
HFD1_k127_1654172_7 PFAM Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 364.0
HFD1_k127_1654172_8 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 315.0
HFD1_k127_1654172_9 Carboxypeptidase regulatory-like domain - - - 0.00001551 48.0
HFD1_k127_170080_0 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 1.55e-294 913.0
HFD1_k127_170080_1 Prolyl oligopeptidase family - - - 1.158e-199 642.0
HFD1_k127_170080_2 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 452.0
HFD1_k127_170080_3 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 401.0
HFD1_k127_170080_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 298.0
HFD1_k127_170080_5 periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000002448 161.0
HFD1_k127_1708897_0 PFAM Glycosyl hydrolase family 3 C terminal domain - - - 1.491e-261 827.0
HFD1_k127_1708897_1 Putative carbohydrate binding domain K12373 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003745 280.0
HFD1_k127_1717392_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 462.0
HFD1_k127_1717392_1 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.00000000000000000003109 94.0
HFD1_k127_1719824_0 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 491.0
HFD1_k127_1719824_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 497.0
HFD1_k127_1719824_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000003127 233.0
HFD1_k127_1719824_3 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000209 221.0
HFD1_k127_1719824_4 Regulatory protein - - - 0.0000000000000000000000002815 111.0
HFD1_k127_1723566_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 436.0
HFD1_k127_1723566_1 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 297.0
HFD1_k127_1723566_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000004209 229.0
HFD1_k127_1723566_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000003871 171.0
HFD1_k127_1723566_4 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000006295 59.0
HFD1_k127_173276_0 Prolyl oligopeptidase family - - - 1.817e-256 813.0
HFD1_k127_173276_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 639.0
HFD1_k127_173276_10 PFAM Transposase IS200-like K07491 - - 0.0000001173 63.0
HFD1_k127_173276_11 Pfam Plasmid stabilisation system protein - - - 0.0000002377 54.0
HFD1_k127_173276_12 Transposase K07491 - - 0.00001137 57.0
HFD1_k127_173276_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 356.0
HFD1_k127_173276_3 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 353.0
HFD1_k127_173276_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000003423 186.0
HFD1_k127_173276_5 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000001723 142.0
HFD1_k127_173276_6 Ankyrin repeat - - - 0.00000000000000000000000006342 118.0
HFD1_k127_173276_7 response regulator, receiver - - - 0.000000000000000000000001934 112.0
HFD1_k127_173276_8 Cupin 2, conserved barrel domain protein K21700 - - 0.000000000000000562 82.0
HFD1_k127_173276_9 Nuclease K07004 - - 0.00000000008211 72.0
HFD1_k127_1735840_0 ASPIC and UnbV - - - 3.094e-245 770.0
HFD1_k127_1735840_1 ASPIC and UnbV - - - 4.003e-223 703.0
HFD1_k127_1735840_10 kinesin light chain - - - 0.0000001327 64.0
HFD1_k127_1735840_11 Cytochrome c554 and c-prime - - - 0.0005888 46.0
HFD1_k127_1735840_2 ASPIC and UnbV - - - 1.881e-200 640.0
HFD1_k127_1735840_3 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 584.0
HFD1_k127_1735840_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 432.0
HFD1_k127_1735840_5 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000002694 218.0
HFD1_k127_1735840_6 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000001878 192.0
HFD1_k127_1735840_7 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000001338 173.0
HFD1_k127_1735840_8 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000001345 160.0
HFD1_k127_1735840_9 peptidyl-tyrosine sulfation - - - 0.0000000715 55.0
HFD1_k127_1778294_0 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 533.0
HFD1_k127_1778294_1 PFAM Basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 334.0
HFD1_k127_1778294_2 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 302.0
HFD1_k127_1778294_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002091 287.0
HFD1_k127_1778294_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate - - - 0.0000000000000000000000000000000000000000000000000006659 190.0
HFD1_k127_179378_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1318.0
HFD1_k127_179378_1 PFAM Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.962e-198 628.0
HFD1_k127_179378_10 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000005495 184.0
HFD1_k127_179378_11 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000007922 188.0
HFD1_k127_179378_12 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000003879 137.0
HFD1_k127_179378_13 Domain of unknown function (DUF4440) - - - 0.0000000000000000005462 92.0
HFD1_k127_179378_14 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000243 78.0
HFD1_k127_179378_2 DNA polymerase beta thumb K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 541.0
HFD1_k127_179378_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 306.0
HFD1_k127_179378_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 285.0
HFD1_k127_179378_5 endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003052 295.0
HFD1_k127_179378_6 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003149 273.0
HFD1_k127_179378_7 - - - - 0.00000000000000000000000000000000000000000000000000000000005964 213.0
HFD1_k127_179378_8 EamA-like transporter family K07790 - - 0.0000000000000000000000000000000000000000000000000008113 194.0
HFD1_k127_179378_9 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000000000000000005265 190.0
HFD1_k127_1795278_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.603e-258 811.0
HFD1_k127_1795278_1 Peptidase S46 - - - 2.651e-230 732.0
HFD1_k127_1795278_10 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000001751 229.0
HFD1_k127_1795278_11 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000187 191.0
HFD1_k127_1795278_12 - - - - 0.00000000000000000000000000000000000000000000000004254 194.0
HFD1_k127_1795278_13 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000001062 149.0
HFD1_k127_1795278_14 TIGRFAM Na Ca antiporter, CaCA family K07301 - - 0.000000000000000000000000000000001199 132.0
HFD1_k127_1795278_15 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000203 121.0
HFD1_k127_1795278_16 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000005368 113.0
HFD1_k127_1795278_17 Lipopolysaccharide-assembly - - - 0.000000000000001394 83.0
HFD1_k127_1795278_18 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.000000000000009297 82.0
HFD1_k127_1795278_19 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000009782 75.0
HFD1_k127_1795278_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 6.063e-219 703.0
HFD1_k127_1795278_20 N-formylglutamate amidohydrolase - - - 0.0000000118 62.0
HFD1_k127_1795278_21 - - - - 0.0008962 48.0
HFD1_k127_1795278_3 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 516.0
HFD1_k127_1795278_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 406.0
HFD1_k127_1795278_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 404.0
HFD1_k127_1795278_6 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 394.0
HFD1_k127_1795278_7 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 381.0
HFD1_k127_1795278_8 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001405 284.0
HFD1_k127_1795278_9 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000007161 243.0
HFD1_k127_1801565_0 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 533.0
HFD1_k127_1801565_1 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 500.0
HFD1_k127_1807108_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 392.0
HFD1_k127_1807108_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000594 183.0
HFD1_k127_1807108_2 RDD family - - - 0.0000000007539 64.0
HFD1_k127_1814215_0 phosphorylase K00688 - 2.4.1.1 1.88e-229 728.0
HFD1_k127_1814215_1 Leucine-rich repeat K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 358.0
HFD1_k127_1814215_10 Protein of unknown function (DUF2847) - - - 0.0000000000000000009924 91.0
HFD1_k127_1814215_11 Domain of unknown function (DUF4384) - - - 0.000000000000000008926 94.0
HFD1_k127_1814215_2 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000004121 196.0
HFD1_k127_1814215_3 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000001244 209.0
HFD1_k127_1814215_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.000000000000000000000000000000000000000000000000001366 194.0
HFD1_k127_1814215_6 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000001499 144.0
HFD1_k127_1814215_7 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000003881 117.0
HFD1_k127_1814215_8 - - - - 0.000000000000000000000000004223 112.0
HFD1_k127_1814215_9 Protein of unknown function (DUF971) - - - 0.000000000000000000000006445 104.0
HFD1_k127_1819227_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 4.522e-293 918.0
HFD1_k127_1819227_1 outer membrane efflux protein - - - 9.221e-196 622.0
HFD1_k127_1819227_10 Predicted membrane protein (DUF2306) - - - 0.00000000001761 68.0
HFD1_k127_1819227_11 Predicted membrane protein (DUF2306) - - - 0.0003134 46.0
HFD1_k127_1819227_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 504.0
HFD1_k127_1819227_3 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 512.0
HFD1_k127_1819227_4 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 482.0
HFD1_k127_1819227_5 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 485.0
HFD1_k127_1819227_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000004981 221.0
HFD1_k127_1819227_8 - - - - 0.0000000000000000003599 89.0
HFD1_k127_1819227_9 amine dehydrogenase activity - - - 0.000000000000000231 91.0
HFD1_k127_1829640_0 CHAT domain - - - 5.107e-303 966.0
HFD1_k127_1829640_1 Radical SAM - - - 8.852e-219 696.0
HFD1_k127_1829640_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 289.0
HFD1_k127_1829640_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000002319 258.0
HFD1_k127_1829640_4 Domain of unknown function (DUF4157) K01227,K01448,K03791,K13277,K17733 - 3.2.1.96,3.5.1.28 0.0000000000000000000000000000000000000000000000000000001052 208.0
HFD1_k127_1829640_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000002221 66.0
HFD1_k127_1829640_6 sulfurtransferase - - - 0.000001045 50.0
HFD1_k127_1829640_7 GAF domain K02482 - 2.7.13.3 0.0000143 51.0
HFD1_k127_186309_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 334.0
HFD1_k127_186309_1 PQQ-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001061 218.0
HFD1_k127_186309_2 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000003402 203.0
HFD1_k127_186309_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000001419 119.0
HFD1_k127_186309_4 PFAM Forkhead-associated protein - - - 0.0000000000000000000008431 102.0
HFD1_k127_1888071_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 306.0
HFD1_k127_1888071_1 RNA 2'-O ribose methyltransferase substrate binding K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000003076 255.0
HFD1_k127_1888071_2 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000365 237.0
HFD1_k127_1888071_3 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000009411 241.0
HFD1_k127_1888071_4 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000002527 214.0
HFD1_k127_1888071_5 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000003391 103.0
HFD1_k127_1888071_6 MoeZ MoeB domain K21029 - 2.7.7.80 0.0000000001276 64.0
HFD1_k127_1888071_7 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K10126 - - 0.000267 51.0
HFD1_k127_189876_0 Carboxypeptidase regulatory-like domain - - - 4.921e-247 799.0
HFD1_k127_189876_1 MatE - - - 8.44e-218 684.0
HFD1_k127_189876_10 Transglutaminase-like superfamily - - - 0.0000000000000000009045 95.0
HFD1_k127_189876_11 sequence-specific DNA binding - - - 0.00000000000006104 82.0
HFD1_k127_189876_2 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 620.0
HFD1_k127_189876_3 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 369.0
HFD1_k127_189876_4 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 334.0
HFD1_k127_189876_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003333 264.0
HFD1_k127_189876_6 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000008027 269.0
HFD1_k127_189876_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000001008 230.0
HFD1_k127_189876_8 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000003606 213.0
HFD1_k127_189876_9 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000001173 152.0
HFD1_k127_1918010_0 arylsulfatase activity K01130 - 3.1.6.1 0.0 1304.0
HFD1_k127_1918010_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.201e-215 682.0
HFD1_k127_1918010_2 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 340.0
HFD1_k127_1918010_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000007092 253.0
HFD1_k127_1918010_4 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000542 215.0
HFD1_k127_1918010_5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000001239 179.0
HFD1_k127_1918010_6 Protein of unknown function (DUF2490) - - - 0.000000000000000000000000000000000139 142.0
HFD1_k127_1918010_7 iron assimilation - - - 0.00000008421 55.0
HFD1_k127_1918010_8 - - - - 0.000006884 49.0
HFD1_k127_1920309_0 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 547.0
HFD1_k127_1920309_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 508.0
HFD1_k127_1920309_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000003774 243.0
HFD1_k127_1920309_11 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000797 237.0
HFD1_k127_1920309_13 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000003893 178.0
HFD1_k127_1920309_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000004947 165.0
HFD1_k127_1920309_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000001045 160.0
HFD1_k127_1920309_16 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000005302 132.0
HFD1_k127_1920309_17 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000001312 121.0
HFD1_k127_1920309_18 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.000000000000000000000000003891 115.0
HFD1_k127_1920309_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000001355 104.0
HFD1_k127_1920309_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 500.0
HFD1_k127_1920309_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000004752 73.0
HFD1_k127_1920309_21 transposition, DNA-mediated - - - 0.0000000000005001 74.0
HFD1_k127_1920309_22 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000004433 51.0
HFD1_k127_1920309_23 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00002515 51.0
HFD1_k127_1920309_3 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 439.0
HFD1_k127_1920309_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 422.0
HFD1_k127_1920309_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 366.0
HFD1_k127_1920309_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 337.0
HFD1_k127_1920309_7 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002067 265.0
HFD1_k127_1920309_8 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004749 260.0
HFD1_k127_1920309_9 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002932 256.0
HFD1_k127_1956062_0 ribosome binding - - - 1.226e-195 623.0
HFD1_k127_1956062_1 ATPase involved in DNA repair K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 461.0
HFD1_k127_1956681_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 473.0
HFD1_k127_1956681_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 362.0
HFD1_k127_1956681_10 - - - - 0.00003452 55.0
HFD1_k127_1956681_2 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001187 269.0
HFD1_k127_1956681_3 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000000000000000006576 222.0
HFD1_k127_1956681_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000003735 192.0
HFD1_k127_1956681_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000005082 155.0
HFD1_k127_1956681_6 - - - - 0.000000000000000005439 92.0
HFD1_k127_1956681_7 Glyoxalase-like domain - - - 0.000000000000000006384 89.0
HFD1_k127_1956681_8 multi-organism process - - - 0.000000000001439 81.0
HFD1_k127_1956681_9 Putative adhesin - - - 0.000000009663 65.0
HFD1_k127_195846_0 Glycine D-amino acid oxidase (deaminating) - - - 5.898e-204 646.0
HFD1_k127_195846_1 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 430.0
HFD1_k127_195846_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 387.0
HFD1_k127_195846_3 heat shock protein binding K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 336.0
HFD1_k127_195846_4 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001991 269.0
HFD1_k127_195846_5 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000402 211.0
HFD1_k127_195846_6 Plasmid stabilization - - - 0.000000000000000000000003667 103.0
HFD1_k127_195846_7 - - - - 0.0000000000000003546 79.0
HFD1_k127_195846_9 - - - - 0.000000000003851 67.0
HFD1_k127_1958512_0 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 460.0
HFD1_k127_1958512_1 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 336.0
HFD1_k127_1958512_10 DNA polymerase K02347 - - 0.00000000000000000000000003818 113.0
HFD1_k127_1958512_11 RDD family - - - 0.000000001167 65.0
HFD1_k127_1958512_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 322.0
HFD1_k127_1958512_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000009707 258.0
HFD1_k127_1958512_4 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000971 251.0
HFD1_k127_1958512_5 Pfam Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003519 240.0
HFD1_k127_1958512_6 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002437 238.0
HFD1_k127_1958512_7 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000001509 216.0
HFD1_k127_1958512_9 - - - - 0.00000000000000000000000001469 117.0
HFD1_k127_1967338_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1117.0
HFD1_k127_1967338_1 outer membrane efflux protein K15725 - - 0.000000000000002085 89.0
HFD1_k127_2012745_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 617.0
HFD1_k127_2012745_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 456.0
HFD1_k127_2012745_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000004366 246.0
HFD1_k127_2012745_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003604 243.0
HFD1_k127_2012745_4 Thioesterase superfamily K07107 - - 0.0000000000000000000002188 102.0
HFD1_k127_2015800_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 593.0
HFD1_k127_2015800_1 PFAM TonB-dependent Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 417.0
HFD1_k127_2015800_10 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000006367 114.0
HFD1_k127_2015800_11 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000144 117.0
HFD1_k127_2015800_12 TIGRFAM VWFA-related Acidobacterial domain K07114 - - 0.0000000004609 71.0
HFD1_k127_2015800_13 M61 glycyl aminopeptidase - - - 0.000000001962 70.0
HFD1_k127_2015800_14 - - - - 0.000000003088 64.0
HFD1_k127_2015800_15 snoRNA binding - - - 0.00000001708 61.0
HFD1_k127_2015800_16 Sh3 type 3 domain protein - - - 0.00000003913 65.0
HFD1_k127_2015800_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 394.0
HFD1_k127_2015800_3 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 357.0
HFD1_k127_2015800_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 305.0
HFD1_k127_2015800_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 283.0
HFD1_k127_2015800_6 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008691 256.0
HFD1_k127_2015800_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001185 253.0
HFD1_k127_2015800_8 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000008591 210.0
HFD1_k127_2015800_9 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000002095 156.0
HFD1_k127_202107_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.31e-197 646.0
HFD1_k127_202107_1 including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 305.0
HFD1_k127_202107_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.00000000000000000000000000000000003107 153.0
HFD1_k127_202107_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000001408 74.0
HFD1_k127_2034299_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 475.0
HFD1_k127_2034299_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 391.0
HFD1_k127_2034299_10 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.00000000000000000000000001823 113.0
HFD1_k127_2034299_11 Gas vesicle synthesis protein GvpL/GvpF - - - 0.00000000000000000006989 99.0
HFD1_k127_2034299_12 gas vesicle protein - - - 0.00000000003915 67.0
HFD1_k127_2034299_2 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 364.0
HFD1_k127_2034299_3 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 344.0
HFD1_k127_2034299_4 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000001151 209.0
HFD1_k127_2034299_5 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000005835 142.0
HFD1_k127_2034299_6 Gas vesicle synthesis protein GvpL/GvpF - - - 0.000000000000000000000000000000000004927 147.0
HFD1_k127_2034299_7 Transcriptional regulator - - - 0.00000000000000000000000000000006026 131.0
HFD1_k127_2034299_8 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.000000000000000000000000000001422 123.0
HFD1_k127_2034299_9 Gas vesicle - - - 0.00000000000000000000000000002343 121.0
HFD1_k127_2034387_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 346.0
HFD1_k127_2034387_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000002089 76.0
HFD1_k127_2034387_2 oxidoreductase activity - - - 0.00000002963 66.0
HFD1_k127_2062296_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.686e-309 985.0
HFD1_k127_2062296_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 319.0
HFD1_k127_2062296_2 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000001188 257.0
HFD1_k127_2062296_3 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000000000000854 153.0
HFD1_k127_2062296_4 ErfK YbiS YcfS YnhG - - - 0.000000000000009319 87.0
HFD1_k127_2067683_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 3.05e-199 633.0
HFD1_k127_2067683_1 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 598.0
HFD1_k127_2067683_10 cellulose binding - - - 0.00000000000000000000003623 117.0
HFD1_k127_2067683_11 Clostripain family - - - 0.0000002248 64.0
HFD1_k127_2067683_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 481.0
HFD1_k127_2067683_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 433.0
HFD1_k127_2067683_4 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 372.0
HFD1_k127_2067683_5 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 338.0
HFD1_k127_2067683_6 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 323.0
HFD1_k127_2067683_7 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 338.0
HFD1_k127_2067683_8 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000972 277.0
HFD1_k127_2067683_9 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000123 129.0
HFD1_k127_2080487_0 PFAM type II secretion system protein E K02283,K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 571.0
HFD1_k127_2080487_1 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 339.0
HFD1_k127_2080487_2 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000001083 211.0
HFD1_k127_2080487_3 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000000000000000000000000000000000007754 187.0
HFD1_k127_2080487_4 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000006239 148.0
HFD1_k127_2080487_5 Cellulose biosynthesis protein BcsQ K02282 - - 0.00000000001233 70.0
HFD1_k127_2080487_6 Tetratricopeptide repeat - - - 0.0000005351 61.0
HFD1_k127_2108302_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.67e-201 633.0
HFD1_k127_2108302_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 413.0
HFD1_k127_2148238_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1700.0
HFD1_k127_2148238_1 CHASE3 domain - - - 3.413e-246 775.0
HFD1_k127_2148238_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 299.0
HFD1_k127_2148238_3 - - - - 0.000000000000000000000000000001353 132.0
HFD1_k127_2157484_0 Amino acid permease - - - 1.389e-200 644.0
HFD1_k127_2157484_1 protein histidine kinase activity K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 379.0
HFD1_k127_2157484_2 phosphorelay signal transduction system K02490 - - 0.000000000000000000000000000000000000000000009145 173.0
HFD1_k127_2157484_3 protein histidine kinase activity - - - 0.000000000000000000000000000000000000006164 162.0
HFD1_k127_2174959_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 500.0
HFD1_k127_2174959_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 477.0
HFD1_k127_2174959_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 361.0
HFD1_k127_2174959_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000003433 124.0
HFD1_k127_2174959_4 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.0000000000000000000000000001675 115.0
HFD1_k127_2176359_0 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 603.0
HFD1_k127_2176359_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 552.0
HFD1_k127_2176359_10 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000004252 205.0
HFD1_k127_2176359_11 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000009232 188.0
HFD1_k127_2176359_12 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000000000000000000000000000001607 187.0
HFD1_k127_2176359_13 mannose-6-phosphate isomerase K01809,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000002376 153.0
HFD1_k127_2176359_14 glyoxalase III activity - - - 0.000000000000000000000000001839 115.0
HFD1_k127_2176359_16 Redoxin - - - 0.0000000000001147 75.0
HFD1_k127_2176359_17 - - - - 0.00000000002398 73.0
HFD1_k127_2176359_18 alkyl hydroperoxide reductase - - - 0.0009716 48.0
HFD1_k127_2176359_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 479.0
HFD1_k127_2176359_3 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 373.0
HFD1_k127_2176359_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 344.0
HFD1_k127_2176359_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 330.0
HFD1_k127_2176359_6 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003636 276.0
HFD1_k127_2176359_7 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
HFD1_k127_2176359_8 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000002242 215.0
HFD1_k127_2176359_9 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000008447 205.0
HFD1_k127_2197619_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 4.435e-270 841.0
HFD1_k127_2197619_1 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 6.176e-199 636.0
HFD1_k127_2197619_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 471.0
HFD1_k127_2197619_3 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004904 251.0
HFD1_k127_2197619_4 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000009693 163.0
HFD1_k127_22000_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000003669 181.0
HFD1_k127_22000_1 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000004646 142.0
HFD1_k127_22000_2 STAS domain K04749 - - 0.00000000000000000000000000000000018 135.0
HFD1_k127_22000_3 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000003419 102.0
HFD1_k127_22000_4 Tetratricopeptide repeat - - - 0.00000000114 71.0
HFD1_k127_2234867_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 546.0
HFD1_k127_2234867_1 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 387.0
HFD1_k127_2234867_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 300.0
HFD1_k127_2234867_3 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000007175 255.0
HFD1_k127_2234867_4 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 GO:0008150,GO:0009636,GO:0042221,GO:0050896 - 0.00005007 50.0
HFD1_k127_2253355_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 476.0
HFD1_k127_2253355_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 404.0
HFD1_k127_2253355_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 307.0
HFD1_k127_2265204_0 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 487.0
HFD1_k127_2265204_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 308.0
HFD1_k127_2265204_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000225 207.0
HFD1_k127_2265204_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000008032 141.0
HFD1_k127_2265204_4 Anti-sigma-K factor rskA - - - 0.0000000000000000000006314 106.0
HFD1_k127_2265204_5 - - - - 0.00000007265 61.0
HFD1_k127_22878_0 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 520.0
HFD1_k127_22878_1 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 519.0
HFD1_k127_22878_2 - - - - 0.00000000000000000000004328 100.0
HFD1_k127_2300237_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000004796 211.0
HFD1_k127_2300237_1 cell redox homeostasis K03671 - - 0.0000000000000000000004027 104.0
HFD1_k127_2300237_2 Tetratricopeptide repeat - - - 0.000000005825 68.0
HFD1_k127_2327150_0 Carboxypeptidase regulatory-like domain - - - 0.0 1159.0
HFD1_k127_2327150_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.966e-210 666.0
HFD1_k127_2327150_2 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000000000000001003 235.0
HFD1_k127_2327150_3 hydrolase, family 3 K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000007627 203.0
HFD1_k127_2327150_4 PFAM Transcription regulator MerR DNA binding K08365,K13638 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000416 119.0
HFD1_k127_2338655_0 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 556.0
HFD1_k127_2338655_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 477.0
HFD1_k127_2338655_2 PAS domain containing protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 336.0
HFD1_k127_2338655_3 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000001029 121.0
HFD1_k127_2338655_4 PEP-CTERM motif - - - 0.00000007842 62.0
HFD1_k127_239897_0 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 447.0
HFD1_k127_2410304_0 Tricorn protease homolog - - - 0.0 1341.0
HFD1_k127_2410304_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1287.0
HFD1_k127_2410304_2 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 5.514e-198 632.0
HFD1_k127_2410304_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 299.0
HFD1_k127_2410304_4 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001313 248.0
HFD1_k127_2410304_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001625 220.0
HFD1_k127_2410304_6 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000933 203.0
HFD1_k127_2410304_7 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000001016 168.0
HFD1_k127_2410304_8 - - - - 0.0000000003827 66.0
HFD1_k127_2410304_9 - - - - 0.000009213 52.0
HFD1_k127_2415371_0 Dienelactone hydrolase family - - - 5.669e-319 990.0
HFD1_k127_2415371_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 9.574e-219 690.0
HFD1_k127_2415371_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 419.0
HFD1_k127_2415371_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 370.0
HFD1_k127_2415371_4 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008919 237.0
HFD1_k127_2415371_5 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000046 158.0
HFD1_k127_2415371_6 Pilus assembly protein PilX K02673 - - 0.000000000000000000945 99.0
HFD1_k127_2417606_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 597.0
HFD1_k127_2417606_1 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 437.0
HFD1_k127_2417606_10 Glycosyl transferase 4-like - - - 0.000000000000000000000000001524 116.0
HFD1_k127_2417606_11 Methyltransferase domain - - - 0.000000000000000000000000007535 122.0
HFD1_k127_2417606_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00002955 56.0
HFD1_k127_2417606_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 382.0
HFD1_k127_2417606_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 297.0
HFD1_k127_2417606_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004261 275.0
HFD1_k127_2417606_5 carbamoyl transferase, NodU family K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000463 223.0
HFD1_k127_2417606_6 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000133 204.0
HFD1_k127_2417606_7 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000001748 196.0
HFD1_k127_2417606_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000005861 194.0
HFD1_k127_2417606_9 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000007348 152.0
HFD1_k127_2418623_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 509.0
HFD1_k127_2418623_1 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 426.0
HFD1_k127_2418623_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 352.0
HFD1_k127_2449827_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.022e-236 739.0
HFD1_k127_2449827_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.357e-214 683.0
HFD1_k127_2449827_10 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002589 280.0
HFD1_k127_2449827_11 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000004922 261.0
HFD1_k127_2449827_12 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002255 259.0
HFD1_k127_2449827_13 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000002863 228.0
HFD1_k127_2449827_14 transcriptional regulator - - - 0.00000000000000000000000000000000000000000001021 169.0
HFD1_k127_2449827_15 FAD binding domain K21401 - 1.3.99.38 0.000000000000000000000000000000000000004731 160.0
HFD1_k127_2449827_16 Methyltransferase domain - - - 0.00000000000000000000000000000000001689 145.0
HFD1_k127_2449827_17 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000003918 130.0
HFD1_k127_2449827_18 VanZ like family - - - 0.0000000000000000000000000003708 119.0
HFD1_k127_2449827_19 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000002504 111.0
HFD1_k127_2449827_2 TonB dependent receptor - - - 1.185e-209 698.0
HFD1_k127_2449827_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000001301 113.0
HFD1_k127_2449827_21 Jag_N K06346 - - 0.000000000000000000000001531 109.0
HFD1_k127_2449827_22 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000001341 68.0
HFD1_k127_2449827_23 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000002598 65.0
HFD1_k127_2449827_24 Tetratricopeptide repeat - - - 0.000000001431 70.0
HFD1_k127_2449827_25 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000005217 64.0
HFD1_k127_2449827_26 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000001397 56.0
HFD1_k127_2449827_3 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 495.0
HFD1_k127_2449827_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 492.0
HFD1_k127_2449827_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 446.0
HFD1_k127_2449827_6 virion core protein (lumpy skin disease virus) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 403.0
HFD1_k127_2449827_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 385.0
HFD1_k127_2449827_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 303.0
HFD1_k127_2449827_9 Sporulation initiation inhibitor protein Soj K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 297.0
HFD1_k127_2463085_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 516.0
HFD1_k127_2463085_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 325.0
HFD1_k127_2463085_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 306.0
HFD1_k127_2463085_3 shikimate 3-dehydrogenase (NADP+) activity K00014,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 299.0
HFD1_k127_2463085_5 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000000000000000000486 104.0
HFD1_k127_2463085_6 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.000000000007241 78.0
HFD1_k127_2500423_0 Peptidase inhibitor I9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 547.0
HFD1_k127_2500423_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 267.0
HFD1_k127_2500423_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002521 278.0
HFD1_k127_2500423_3 PQQ-like domain - - - 0.00000000000000000000000000008738 124.0
HFD1_k127_2500423_5 TPM domain K06872 - - 0.00000000000007856 80.0
HFD1_k127_2500423_6 - - - - 0.0000000001058 63.0
HFD1_k127_2500423_8 Aldo/keto reductase family - - - 0.00001716 49.0
HFD1_k127_2506005_0 - - - - 0.000000000000000000000000000000000000000000005715 175.0
HFD1_k127_2506005_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000433 98.0
HFD1_k127_2537952_0 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 370.0
HFD1_k127_2537952_1 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009228 278.0
HFD1_k127_2537952_2 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003653 259.0
HFD1_k127_2537952_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000006056 207.0
HFD1_k127_2537952_4 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000004495 170.0
HFD1_k127_2537952_5 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000003469 185.0
HFD1_k127_2537952_6 Belongs to the Fur family K09825 - - 0.0000000000000000000000000000002523 127.0
HFD1_k127_2537952_7 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000113 115.0
HFD1_k127_2537952_8 Integral membrane protein CcmA involved in cell shape determination - - - 0.000006327 51.0
HFD1_k127_2540004_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 543.0
HFD1_k127_2540004_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 538.0
HFD1_k127_2540004_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 466.0
HFD1_k127_2540004_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 456.0
HFD1_k127_2540004_4 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 448.0
HFD1_k127_2540004_5 Clostripain family - - - 0.0000000000000000000000000008167 130.0
HFD1_k127_2540004_7 - - - - 0.00000000721 66.0
HFD1_k127_2540004_8 Patatin-like phospholipase K06900 - - 0.00000001548 62.0
HFD1_k127_2540004_9 Esterase PHB depolymerase - - - 0.00000375 57.0
HFD1_k127_2564709_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 431.0
HFD1_k127_2564709_1 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 382.0
HFD1_k127_2564709_2 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000002232 190.0
HFD1_k127_2564709_3 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.00000000000000000000000000000000000002853 157.0
HFD1_k127_2564709_4 PFAM Polysaccharide export protein K01991 - - 0.00000000000001488 85.0
HFD1_k127_2564709_5 AAA ATPase domain K02450 - - 0.000000001964 62.0
HFD1_k127_2564709_6 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.000001545 61.0
HFD1_k127_2595000_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1439.0
HFD1_k127_2595000_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1206.0
HFD1_k127_2595000_10 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 370.0
HFD1_k127_2595000_11 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 319.0
HFD1_k127_2595000_12 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006109 284.0
HFD1_k127_2595000_13 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002696 252.0
HFD1_k127_2595000_14 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000008216 236.0
HFD1_k127_2595000_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001918 211.0
HFD1_k127_2595000_16 - - - - 0.0000000000000000000000000000000000000000000000001943 183.0
HFD1_k127_2595000_17 FR47-like protein - - - 0.000000000000000000000000000000000000000000002479 169.0
HFD1_k127_2595000_18 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000000000005083 164.0
HFD1_k127_2595000_19 PFAM BioY protein K03523 - - 0.0000000000000000000000000000000000000002285 156.0
HFD1_k127_2595000_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 3.686e-259 812.0
HFD1_k127_2595000_20 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000005814 142.0
HFD1_k127_2595000_21 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000000000001097 142.0
HFD1_k127_2595000_22 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000005322 141.0
HFD1_k127_2595000_23 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.00000000000000000000000000000000006515 143.0
HFD1_k127_2595000_24 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000002582 125.0
HFD1_k127_2595000_25 Tricorn protease C1 domain K08676 - - 0.0000000000000000000000000000007812 123.0
HFD1_k127_2595000_26 Urate oxidase N-terminal - - - 0.00000000000000000000000000000326 130.0
HFD1_k127_2595000_27 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000008451 125.0
HFD1_k127_2595000_28 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000001836 120.0
HFD1_k127_2595000_29 Protein of unknown function (DUF445) - - - 0.000000000000000000001751 109.0
HFD1_k127_2595000_3 PFAM Amino acid permease K03294 - - 1.115e-224 711.0
HFD1_k127_2595000_30 Universal stress protein - - - 0.00000000000001852 83.0
HFD1_k127_2595000_31 Rhodanese Homology Domain - - - 0.00000000001861 68.0
HFD1_k127_2595000_32 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000006317 70.0
HFD1_k127_2595000_33 outer membrane autotransporter barrel domain protein - - - 0.000001754 57.0
HFD1_k127_2595000_4 5TM C-terminal transporter carbon starvation CstA K06200 - - 3.034e-218 693.0
HFD1_k127_2595000_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 613.0
HFD1_k127_2595000_6 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 498.0
HFD1_k127_2595000_7 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 479.0
HFD1_k127_2595000_8 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 417.0
HFD1_k127_2595000_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 392.0
HFD1_k127_2597817_0 Hydrolase CocE NonD family - - - 2.084e-314 972.0
HFD1_k127_2597817_1 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.348e-233 731.0
HFD1_k127_2597817_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 614.0
HFD1_k127_2597817_3 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000003623 178.0
HFD1_k127_2597817_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000005191 165.0
HFD1_k127_2597817_5 - - - - 0.000000000000005088 79.0
HFD1_k127_2644390_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 586.0
HFD1_k127_2644390_1 Peptidase, S9A B C family, catalytic domain protein K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 501.0
HFD1_k127_2644390_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
HFD1_k127_2644390_3 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 371.0
HFD1_k127_2644390_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 364.0
HFD1_k127_2644390_5 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 329.0
HFD1_k127_2644390_6 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 312.0
HFD1_k127_2644390_7 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 295.0
HFD1_k127_2644390_8 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000004513 166.0
HFD1_k127_2644390_9 Protein of unknown function (DUF983) - - - 0.0000000002707 67.0
HFD1_k127_264901_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 2.287e-257 807.0
HFD1_k127_264901_1 Protein of unknown function (DUF763) K09003 - - 5.623e-196 617.0
HFD1_k127_264901_10 DinB family - - - 0.000000000000000000000000000000000000000000000000556 180.0
HFD1_k127_264901_11 Cupin domain - - - 0.0000000000000000000000000000000000000000000000008892 177.0
HFD1_k127_264901_12 Penicillin-binding Protein K05364 - - 0.0000000000000000000000000000000000000000002691 179.0
HFD1_k127_264901_13 serine-type endopeptidase activity K14645,K20276 - - 0.00000000000000000000000000000004854 135.0
HFD1_k127_264901_14 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.0000000000000000000000000000001617 141.0
HFD1_k127_264901_15 Belongs to the ompA family - - - 0.00000000000000000000001598 113.0
HFD1_k127_264901_17 cellulase activity - - - 0.0000000000000000004315 102.0
HFD1_k127_264901_18 (FHA) domain - - - 0.00000000002698 74.0
HFD1_k127_264901_19 Outer membrane protein (OmpH-like) K06142 - - 0.00000001823 63.0
HFD1_k127_264901_2 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 593.0
HFD1_k127_264901_20 Domain of unknown function (DUF4132) - - - 0.0003598 53.0
HFD1_k127_264901_3 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 501.0
HFD1_k127_264901_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 527.0
HFD1_k127_264901_5 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 463.0
HFD1_k127_264901_6 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 462.0
HFD1_k127_264901_7 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 322.0
HFD1_k127_264901_8 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 296.0
HFD1_k127_264901_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000001659 198.0
HFD1_k127_2659438_0 beta-lactamase - - - 7.942e-254 806.0
HFD1_k127_2659438_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.995e-246 775.0
HFD1_k127_2659438_10 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000002292 235.0
HFD1_k127_2659438_11 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000003011 191.0
HFD1_k127_2659438_12 BadF BadG BcrA BcrD - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000007294 168.0
HFD1_k127_2659438_13 LysR substrate binding domain K21703 - - 0.00000000000000000000000000000000000000741 157.0
HFD1_k127_2659438_14 SMART Rhodanese domain protein - - - 0.000003583 49.0
HFD1_k127_2659438_2 Sodium:solute symporter family - - - 2.094e-244 769.0
HFD1_k127_2659438_3 Domain of unknown function (DUF3536) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 514.0
HFD1_k127_2659438_4 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 497.0
HFD1_k127_2659438_5 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 459.0
HFD1_k127_2659438_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 445.0
HFD1_k127_2659438_7 symporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 380.0
HFD1_k127_2659438_8 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000282 289.0
HFD1_k127_2659438_9 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000005936 238.0
HFD1_k127_2668551_0 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 353.0
HFD1_k127_2668551_1 PFAM Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 334.0
HFD1_k127_2668551_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000008642 88.0
HFD1_k127_2668551_3 Protein conserved in bacteria - - - 0.0000000009136 72.0
HFD1_k127_267743_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 605.0
HFD1_k127_267743_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 370.0
HFD1_k127_267743_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000003534 205.0
HFD1_k127_267743_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000293 153.0
HFD1_k127_267743_4 Ribosomal protein L35 K02916 - - 0.000000000000000004059 85.0
HFD1_k127_267743_5 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000005937 54.0
HFD1_k127_2693562_0 Carboxypeptidase regulatory-like domain - - - 0.0 1040.0
HFD1_k127_2693562_1 Multicopper oxidase - - - 0.0 1035.0
HFD1_k127_2693562_10 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 424.0
HFD1_k127_2693562_11 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 409.0
HFD1_k127_2693562_12 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 331.0
HFD1_k127_2693562_13 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 286.0
HFD1_k127_2693562_14 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 286.0
HFD1_k127_2693562_15 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002236 283.0
HFD1_k127_2693562_16 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003634 260.0
HFD1_k127_2693562_17 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001372 252.0
HFD1_k127_2693562_18 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003768 267.0
HFD1_k127_2693562_19 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000001108 239.0
HFD1_k127_2693562_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 4.236e-285 897.0
HFD1_k127_2693562_20 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001499 244.0
HFD1_k127_2693562_21 Transporter, small conductance mechanosensitive ion channel MscS family protein K03442 - - 0.000000000000000000000000000000000000000000000000000000000001022 222.0
HFD1_k127_2693562_22 membrane - - - 0.0000000000000000000000000000000000000000000000000000000003892 219.0
HFD1_k127_2693562_23 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000002778 201.0
HFD1_k127_2693562_24 Zn-dependent hydrolase, glyoxylase - - - 0.000000000000000000000000000000000000000000000000000002258 202.0
HFD1_k127_2693562_25 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000000000000000001205 186.0
HFD1_k127_2693562_26 Bacterial regulatory proteins, tetR family K13770 - - 0.00000000000000000000000000000000000000000000003627 177.0
HFD1_k127_2693562_27 YCII-related domain - - - 0.000000000000000000000000000000000000000003391 160.0
HFD1_k127_2693562_28 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000004224 156.0
HFD1_k127_2693562_29 - - - - 0.000000000000000000000000000000000002067 158.0
HFD1_k127_2693562_3 PFAM TonB-dependent Receptor Plug K02014,K16089 - - 1.587e-213 685.0
HFD1_k127_2693562_30 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000003967 132.0
HFD1_k127_2693562_31 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000009844 122.0
HFD1_k127_2693562_32 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.00000000000000000008436 98.0
HFD1_k127_2693562_33 transposition K07497 - - 0.0000000000000000006598 89.0
HFD1_k127_2693562_34 Protein of unknown function (DUF2933) - - - 0.00000000000000002358 84.0
HFD1_k127_2693562_35 Protein of unknown function (DUF3142) - - - 0.000000000000008638 87.0
HFD1_k127_2693562_36 - - - - 0.00000000000003289 87.0
HFD1_k127_2693562_37 Carboxypeptidase regulatory-like domain - - - 0.0000000000005262 83.0
HFD1_k127_2693562_38 Response regulator, receiver K11443 - - 0.000000000001826 74.0
HFD1_k127_2693562_4 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 4.365e-195 625.0
HFD1_k127_2693562_40 YceI-like domain - - - 0.00000000001045 73.0
HFD1_k127_2693562_41 COG1918 Fe2 transport system protein A K04758 - - 0.00000000001775 69.0
HFD1_k127_2693562_42 - - - - 0.000000007762 66.0
HFD1_k127_2693562_43 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0000001728 54.0
HFD1_k127_2693562_45 - - - - 0.000006842 60.0
HFD1_k127_2693562_46 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000007653 50.0
HFD1_k127_2693562_5 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 557.0
HFD1_k127_2693562_6 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 540.0
HFD1_k127_2693562_7 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 504.0
HFD1_k127_2693562_8 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 507.0
HFD1_k127_2693562_9 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 412.0
HFD1_k127_2715681_0 Phage tail sheath C-terminal domain K06907 - - 4.623e-265 828.0
HFD1_k127_2715681_1 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000005614 154.0
HFD1_k127_2715681_2 - - - - 0.00000000000000000000004255 105.0
HFD1_k127_2728118_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 345.0
HFD1_k127_2728118_1 Protein of unknown function (DUF1175) K09934 - - 0.000000000000000000000000000000000000000000000000000009691 201.0
HFD1_k127_2728118_2 - - - - 0.0000000000000003252 87.0
HFD1_k127_2728118_3 Alpha-2-Macroglobulin K06894 - - 0.00005265 51.0
HFD1_k127_274290_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 425.0
HFD1_k127_274290_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 404.0
HFD1_k127_274290_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000001839 209.0
HFD1_k127_2745039_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0 1064.0
HFD1_k127_2745039_1 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0 1010.0
HFD1_k127_2745039_2 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000000002449 168.0
HFD1_k127_2745039_3 PFAM TonB-dependent Receptor Plug - - - 0.0008326 44.0
HFD1_k127_275318_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.531e-294 920.0
HFD1_k127_275318_1 2 iron, 2 sulfur cluster binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000004348 211.0
HFD1_k127_275318_2 Wd-40 repeat - - - 0.000000000000000000000000000000000000000000000000000000002662 217.0
HFD1_k127_275696_0 - K13582,K13924,K15580 - 2.1.1.80,3.1.1.61 0.0 1401.0
HFD1_k127_275696_1 - - - - 6.552e-204 651.0
HFD1_k127_275696_2 ribosome binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 490.0
HFD1_k127_275696_3 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 464.0
HFD1_k127_275696_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000001109 203.0
HFD1_k127_275696_5 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000008118 168.0
HFD1_k127_275696_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000001682 96.0
HFD1_k127_275696_7 SurA N-terminal domain K03769,K07533 - 5.2.1.8 0.000000000000000009404 96.0
HFD1_k127_2759268_0 Belongs to the glycosyl hydrolase 28 family - - - 4.622e-194 616.0
HFD1_k127_2759268_1 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 518.0
HFD1_k127_2759268_2 Pectic acid lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 424.0
HFD1_k127_2759268_3 Pectinesterase K01051 - 3.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001368 284.0
HFD1_k127_2779793_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1102.0
HFD1_k127_2779793_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 9.031e-223 702.0
HFD1_k127_2779793_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000003271 95.0
HFD1_k127_2779793_11 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00002414 55.0
HFD1_k127_2779793_2 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 514.0
HFD1_k127_2779793_3 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 445.0
HFD1_k127_2779793_4 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 420.0
HFD1_k127_2779793_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 299.0
HFD1_k127_2779793_6 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000559 226.0
HFD1_k127_2779793_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000007811 160.0
HFD1_k127_2779793_8 Tricorn protease C1 domain K03797 - 3.4.21.102 0.00000000000000000000000000000000000000009496 168.0
HFD1_k127_2779793_9 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000003526 113.0
HFD1_k127_2789675_0 Carboxypeptidase regulatory-like domain - - - 1.207e-268 854.0
HFD1_k127_2805031_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 417.0
HFD1_k127_2805031_1 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 291.0
HFD1_k127_2805031_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000001539 167.0
HFD1_k127_2805031_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000003237 132.0
HFD1_k127_2805031_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000177 128.0
HFD1_k127_2805031_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000004511 94.0
HFD1_k127_2827681_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000008103 229.0
HFD1_k127_2827681_1 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000244 204.0
HFD1_k127_2827681_2 Periplasmic binding protein K02016 - - 0.00000000000000000000000000004803 122.0
HFD1_k127_2845704_0 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 313.0
HFD1_k127_2849464_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 422.0
HFD1_k127_2849464_1 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 336.0
HFD1_k127_2849464_10 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000002185 166.0
HFD1_k127_2849464_11 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000004633 151.0
HFD1_k127_2849464_12 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000007692 145.0
HFD1_k127_2849464_13 proteolysis - - - 0.00000000000000000000000000000001002 141.0
HFD1_k127_2849464_14 WXG100 protein secretion system (Wss), protein YukD - - - 0.00000000000000000000000000008758 118.0
HFD1_k127_2849464_15 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000006478 119.0
HFD1_k127_2849464_16 Trm112p-like protein K09791 - - 0.00000000000000000000006085 99.0
HFD1_k127_2849464_17 3D domain - - - 0.000000000000000003955 91.0
HFD1_k127_2849464_19 Bacterial PH domain K08981 - - 0.0000000052 65.0
HFD1_k127_2849464_2 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 305.0
HFD1_k127_2849464_21 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.00008808 53.0
HFD1_k127_2849464_22 Carboxypeptidase regulatory-like domain - - - 0.0001022 49.0
HFD1_k127_2849464_3 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 309.0
HFD1_k127_2849464_4 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003551 279.0
HFD1_k127_2849464_5 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005974 274.0
HFD1_k127_2849464_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000005015 232.0
HFD1_k127_2849464_7 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000001394 174.0
HFD1_k127_2849464_8 PFAM Ubiquitin-conjugating - - - 0.0000000000000000000000000000000000000000007262 170.0
HFD1_k127_2849464_9 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000002729 158.0
HFD1_k127_285488_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1395.0
HFD1_k127_285488_1 Carboxypeptidase regulatory-like domain - - - 2.634e-315 1004.0
HFD1_k127_285488_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000001895 177.0
HFD1_k127_285488_11 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000769 172.0
HFD1_k127_285488_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.000000000000000000000000000000000000000000001053 172.0
HFD1_k127_285488_13 - - - - 0.00000000000000000001072 96.0
HFD1_k127_285488_14 DoxX K15977 - - 0.00000000000000005732 86.0
HFD1_k127_285488_15 PASTA K12132 - 2.7.11.1 0.00000001339 65.0
HFD1_k127_285488_16 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000007319 55.0
HFD1_k127_285488_18 COGs COG5616 integral membrane protein - - - 0.0008097 47.0
HFD1_k127_285488_2 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 419.0
HFD1_k127_285488_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 346.0
HFD1_k127_285488_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 342.0
HFD1_k127_285488_5 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 289.0
HFD1_k127_285488_6 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000003281 205.0
HFD1_k127_285488_7 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000004213 201.0
HFD1_k127_285488_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000002191 186.0
HFD1_k127_285488_9 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000001165 178.0
HFD1_k127_2902902_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 491.0
HFD1_k127_2902902_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 255.0
HFD1_k127_2902902_2 TPR repeat - - - 0.0000000000000000000002137 103.0
HFD1_k127_293793_0 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 527.0
HFD1_k127_293793_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 319.0
HFD1_k127_293793_2 acetyltransferase - - - 0.0000000000000000000008904 97.0
HFD1_k127_293793_3 D-erythro-sphingosine kinase activity K04718 - 2.7.1.91 0.0000000000002445 78.0
HFD1_k127_2970808_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 554.0
HFD1_k127_2970808_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 456.0
HFD1_k127_2970808_2 OsmC-like protein K06889,K07397 - - 0.00000000000000000000000000000000000005881 148.0
HFD1_k127_2970808_3 Regulatory protein - - - 0.000000000000000000000000005366 115.0
HFD1_k127_2970808_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000114 85.0
HFD1_k127_2970808_5 - - - - 0.0000000001465 68.0
HFD1_k127_2970808_6 - - - - 0.0000000007431 61.0
HFD1_k127_2985918_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 394.0
HFD1_k127_2985918_1 Retroviral aspartyl protease - - - 0.0003034 52.0
HFD1_k127_3005770_0 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 567.0
HFD1_k127_3005770_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 352.0
HFD1_k127_3005770_3 Polymer-forming cytoskeletal - - - 0.0000000000000000499 92.0
HFD1_k127_3005770_4 Carboxypeptidase regulatory-like domain - - - 0.0000001086 66.0
HFD1_k127_3005770_5 HEAT repeat - - - 0.000005504 54.0
HFD1_k127_305210_0 Carboxyl transferase domain - - - 6.689e-236 743.0
HFD1_k127_305210_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 538.0
HFD1_k127_305210_10 - - - - 0.0000000000000000000001052 101.0
HFD1_k127_305210_11 Protein of unknown function (DUF3311) - - - 0.000000000000129 73.0
HFD1_k127_305210_12 Protein of unknown function (DUF433) - - - 0.000000000002195 72.0
HFD1_k127_305210_13 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000001027 66.0
HFD1_k127_305210_14 ankyrin repeat - - - 0.0000000000525 73.0
HFD1_k127_305210_2 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 535.0
HFD1_k127_305210_3 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 406.0
HFD1_k127_305210_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 336.0
HFD1_k127_305210_5 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 310.0
HFD1_k127_305210_6 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002931 276.0
HFD1_k127_305210_7 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000437 215.0
HFD1_k127_305210_8 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000000005142 224.0
HFD1_k127_305210_9 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000001664 139.0
HFD1_k127_3101697_0 serine threonine protein kinase K12132 - 2.7.11.1 6.446e-208 680.0
HFD1_k127_3101697_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 588.0
HFD1_k127_3101697_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000002474 220.0
HFD1_k127_3101697_3 Belongs to the UPF0235 family K09131 - - 0.00000000000000001635 85.0
HFD1_k127_3101697_4 YGGT family K02221 - - 0.000000001158 67.0
HFD1_k127_3101697_6 Bacterial regulatory protein, Fis family - - - 0.00005575 51.0
HFD1_k127_3125636_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.45e-304 945.0
HFD1_k127_3125636_1 TIGRFAM magnesium chelatase, H subunit K03403 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 527.0
HFD1_k127_3125636_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000003117 199.0
HFD1_k127_3125636_11 Tetratricopeptide repeat K02200 - - 0.0000000000000000000000000000000000000000000000000000009463 207.0
HFD1_k127_3125636_12 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000001733 169.0
HFD1_k127_3125636_13 Evidence 4 Homologs of previously reported genes of K03975 - - 0.000000000000121 76.0
HFD1_k127_3125636_14 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000004544 54.0
HFD1_k127_3125636_15 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00001181 58.0
HFD1_k127_3125636_16 Tetratricopeptide TPR_2 repeat protein - - - 0.00004881 53.0
HFD1_k127_3125636_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 436.0
HFD1_k127_3125636_3 Magnesium chelatase, subunit ChlI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 411.0
HFD1_k127_3125636_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 348.0
HFD1_k127_3125636_5 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 332.0
HFD1_k127_3125636_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 306.0
HFD1_k127_3125636_7 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001205 267.0
HFD1_k127_3125636_8 Periplasmic protein thiol K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001366 249.0
HFD1_k127_3125636_9 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000002097 250.0
HFD1_k127_3133332_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.481e-293 922.0
HFD1_k127_3133332_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 502.0
HFD1_k127_3133332_2 AMMECR1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 347.0
HFD1_k127_3133332_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 324.0
HFD1_k127_3133332_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000003946 216.0
HFD1_k127_3133332_5 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000006786 205.0
HFD1_k127_314614_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1323.0
HFD1_k127_314614_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.133e-281 886.0
HFD1_k127_314614_10 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000359 49.0
HFD1_k127_314614_2 Peptidase family M28 - - - 1.505e-209 668.0
HFD1_k127_314614_3 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 331.0
HFD1_k127_314614_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001057 255.0
HFD1_k127_314614_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000001137 234.0
HFD1_k127_314614_6 DinB family - - - 0.00000000000000000000000000000000000000000002068 166.0
HFD1_k127_314614_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000002299 170.0
HFD1_k127_314614_8 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000004796 106.0
HFD1_k127_314614_9 beta-lactamase domain protein - - - 0.0000000000284 66.0
HFD1_k127_3151225_0 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 526.0
HFD1_k127_3151225_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 505.0
HFD1_k127_3151225_10 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000000005068 213.0
HFD1_k127_3151225_11 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000001822 193.0
HFD1_k127_3151225_12 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000005064 118.0
HFD1_k127_3151225_13 Transcriptional regulator, AraC family K18991 - - 0.00000000000000697 79.0
HFD1_k127_3151225_14 - - - - 0.0000000000004392 73.0
HFD1_k127_3151225_15 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000002179 59.0
HFD1_k127_3151225_2 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 499.0
HFD1_k127_3151225_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 415.0
HFD1_k127_3151225_4 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 416.0
HFD1_k127_3151225_5 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 401.0
HFD1_k127_3151225_6 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 384.0
HFD1_k127_3151225_7 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 370.0
HFD1_k127_3151225_8 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 364.0
HFD1_k127_3151225_9 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000002657 244.0
HFD1_k127_3155798_0 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 385.0
HFD1_k127_3155798_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 287.0
HFD1_k127_3155798_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004875 293.0
HFD1_k127_3155798_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000005668 260.0
HFD1_k127_3155798_4 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000008692 224.0
HFD1_k127_3155798_5 ABC-type molybdate transport system, permease component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000003443 223.0
HFD1_k127_3155798_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000001387 172.0
HFD1_k127_3155798_7 outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000000000001812 146.0
HFD1_k127_3155798_8 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000004152 66.0
HFD1_k127_3155798_9 - - - - 0.0008399 49.0
HFD1_k127_3166210_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.745e-304 952.0
HFD1_k127_3166210_1 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 451.0
HFD1_k127_3166210_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009725 284.0
HFD1_k127_3166210_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004163 254.0
HFD1_k127_3166210_4 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.00000000000000000000000000000000000000000001475 168.0
HFD1_k127_3166210_5 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.0000000000000000000000000000000000004095 146.0
HFD1_k127_3183735_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.632e-275 861.0
HFD1_k127_3183735_1 carbohydrate kinase FGGY K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000009284 269.0
HFD1_k127_3183735_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000004794 188.0
HFD1_k127_3183735_3 lipid kinase, YegS Rv2252 BmrU family - - - 0.0000000000000009649 81.0
HFD1_k127_3222855_0 hydrolase family 92 - - - 2.46e-304 961.0
HFD1_k127_3222855_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 580.0
HFD1_k127_3222855_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000003152 201.0
HFD1_k127_3222855_11 Peptidase family M23 - - - 0.00000000000000000000000000000000000008522 154.0
HFD1_k127_3222855_12 SET domain K07117 - - 0.0000000000000000000000000000000499 129.0
HFD1_k127_3222855_13 - - - - 0.00000000000000000000000000001018 126.0
HFD1_k127_3222855_14 Cold-Shock Protein K03704 - - 0.000000000000000000000006182 105.0
HFD1_k127_3222855_15 - - - - 0.00000000000000001698 91.0
HFD1_k127_3222855_17 protein conserved in cyanobacteria - - - 0.0000000135 62.0
HFD1_k127_3222855_2 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 558.0
HFD1_k127_3222855_3 Peptidase family M3 K01284 - 3.4.15.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 484.0
HFD1_k127_3222855_4 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 391.0
HFD1_k127_3222855_5 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 331.0
HFD1_k127_3222855_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 297.0
HFD1_k127_3222855_7 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001247 284.0
HFD1_k127_3222855_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001185 271.0
HFD1_k127_3222855_9 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000001123 200.0
HFD1_k127_3229395_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 491.0
HFD1_k127_3229395_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000004253 226.0
HFD1_k127_3229395_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000001229 165.0
HFD1_k127_3229395_3 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000005918 123.0
HFD1_k127_3240818_0 enterobactin catabolic process - - - 6.155e-287 889.0
HFD1_k127_3240818_1 PFAM DNA mismatch repair protein MutS domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 502.0
HFD1_k127_3240818_2 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 338.0
HFD1_k127_3240818_3 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000000000000000000001247 156.0
HFD1_k127_3240818_4 DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000007891 109.0
HFD1_k127_3246555_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 409.0
HFD1_k127_3246555_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 369.0
HFD1_k127_3246555_2 ATP-binding region, ATPase domain protein - - - 0.0000000000000000000473 94.0
HFD1_k127_3251247_0 Ribosomal protein S1 K02945 - - 3.363e-207 659.0
HFD1_k127_3251247_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 486.0
HFD1_k127_3251247_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 395.0
HFD1_k127_3251247_3 7TM receptor with intracellular metal dependent phosphohydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 357.0
HFD1_k127_3251247_4 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008434 280.0
HFD1_k127_3251247_5 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000001181 196.0
HFD1_k127_3251247_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000001606 187.0
HFD1_k127_3251247_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000001309 169.0
HFD1_k127_3251247_8 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000001192 161.0
HFD1_k127_3251247_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000001971 129.0
HFD1_k127_3251363_0 NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 377.0
HFD1_k127_3251363_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 361.0
HFD1_k127_3251363_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 354.0
HFD1_k127_3251363_3 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 295.0
HFD1_k127_3251363_4 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000042 135.0
HFD1_k127_3260819_0 DNA Topoisomerase IV K02469 - 5.99.1.3 3.688e-304 954.0
HFD1_k127_3260819_1 Urocanase Rossmann-like domain K01712 - 4.2.1.49 1.288e-270 841.0
HFD1_k127_3260819_10 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000002309 96.0
HFD1_k127_3260819_11 - - - - 0.000000000000000000006757 105.0
HFD1_k127_3260819_12 Transcription factor zinc-finger K09981 - - 0.000000000003026 70.0
HFD1_k127_3260819_13 rhodanese-related sulfurtransferase - - - 0.00000000127 63.0
HFD1_k127_3260819_14 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669,K07672 - - 0.00000000414 64.0
HFD1_k127_3260819_2 Aromatic amino acid lyase K01745 - 4.3.1.3 3.742e-200 635.0
HFD1_k127_3260819_3 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 391.0
HFD1_k127_3260819_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 257.0
HFD1_k127_3260819_5 Predicted integral membrane protein (DUF2270) - - - 0.0000000000000000000000000000000000000000000000000000000000000001464 234.0
HFD1_k127_3260819_6 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000003189 201.0
HFD1_k127_3260819_7 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000001204 164.0
HFD1_k127_3260819_8 ATP-dependent protease La (LON) substrate-binding domain K01338 - 3.4.21.53 0.000000000000000000000000000000000000001408 157.0
HFD1_k127_3260819_9 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000004138 122.0
HFD1_k127_327517_0 surface antigen variable number - - - 0.0000000000000000000000000002225 134.0
HFD1_k127_327517_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000001436 106.0
HFD1_k127_327517_2 protein conserved in bacteria K09800 - - 0.00000000001829 79.0
HFD1_k127_3280555_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 398.0
HFD1_k127_3293911_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1245.0
HFD1_k127_3293911_1 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 468.0
HFD1_k127_3293911_10 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000001679 198.0
HFD1_k127_3293911_11 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000001198 207.0
HFD1_k127_3293911_12 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000001167 175.0
HFD1_k127_3293911_13 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000002599 152.0
HFD1_k127_3293911_14 acetyltransferase - - - 0.00000000000000000000000000000000000001167 149.0
HFD1_k127_3293911_15 Phosphoglycerate mutase family - - - 0.0000000000000000000000001356 115.0
HFD1_k127_3293911_16 cell redox homeostasis - - - 0.000000000000000000000006384 109.0
HFD1_k127_3293911_17 PFAM Amidase - - - 0.000000000533 66.0
HFD1_k127_3293911_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 410.0
HFD1_k127_3293911_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 390.0
HFD1_k127_3293911_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 368.0
HFD1_k127_3293911_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003445 285.0
HFD1_k127_3293911_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001386 269.0
HFD1_k127_3293911_7 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 263.0
HFD1_k127_3293911_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000001271 223.0
HFD1_k127_3293911_9 Domain of unknown function (DUF1990) - - - 0.000000000000000000000000000000000000000000000000000000271 199.0
HFD1_k127_3335904_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 573.0
HFD1_k127_3335904_1 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 563.0
HFD1_k127_3335904_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 298.0
HFD1_k127_3335904_11 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001615 290.0
HFD1_k127_3335904_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000001334 211.0
HFD1_k127_3335904_13 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000001318 187.0
HFD1_k127_3335904_14 EVE domain - - - 0.000000000000000000000000000000000000000000000001407 177.0
HFD1_k127_3335904_15 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000324 183.0
HFD1_k127_3335904_16 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000002987 170.0
HFD1_k127_3335904_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000008883 158.0
HFD1_k127_3335904_18 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000009434 156.0
HFD1_k127_3335904_19 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000003429 146.0
HFD1_k127_3335904_2 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 494.0
HFD1_k127_3335904_20 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000004098 109.0
HFD1_k127_3335904_21 surface antigen variable number - - - 0.000000000000000003683 93.0
HFD1_k127_3335904_22 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000001004 77.0
HFD1_k127_3335904_23 mttA/Hcf106 family K03116,K03117 - - 0.00000000000112 73.0
HFD1_k127_3335904_24 peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000001022 68.0
HFD1_k127_3335904_25 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000002168 60.0
HFD1_k127_3335904_3 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 486.0
HFD1_k127_3335904_4 Sodium:sulfate symporter transmembrane region K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 446.0
HFD1_k127_3335904_5 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 419.0
HFD1_k127_3335904_6 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 408.0
HFD1_k127_3335904_7 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 391.0
HFD1_k127_3335904_8 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 342.0
HFD1_k127_3335904_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 317.0
HFD1_k127_3344349_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001058 283.0
HFD1_k127_3344349_1 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000005098 216.0
HFD1_k127_3344349_2 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000004569 206.0
HFD1_k127_3344349_3 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.00000000000000000000000000000000000000001622 163.0
HFD1_k127_3344349_4 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000057 153.0
HFD1_k127_3344349_5 SNARE associated Golgi protein - - - 0.00000000000000004544 89.0
HFD1_k127_3344349_6 PFAM SNARE associated Golgi protein - - - 0.0000000000000002178 87.0
HFD1_k127_3344349_7 Putative glycolipid-binding - - - 0.0000002669 60.0
HFD1_k127_3345760_0 Belongs to the glycosyl hydrolase 43 family - - - 8.503e-217 684.0
HFD1_k127_3345760_1 ABC-type antimicrobial peptide transport system, permease component - - - 4.452e-203 659.0
HFD1_k127_3345760_10 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000003856 240.0
HFD1_k127_3345760_11 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000001087 233.0
HFD1_k127_3345760_12 Predicted membrane protein (DUF2306) - - - 0.0000000000000000000000000000000000000000000000000000000000002028 220.0
HFD1_k127_3345760_14 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000976 184.0
HFD1_k127_3345760_15 - - - - 0.000000000000000000000000000000000000000000001727 171.0
HFD1_k127_3345760_16 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.000000000000000000000000000000004842 151.0
HFD1_k127_3345760_17 protein trimerization - - - 0.00000000000000000000000000000001083 132.0
HFD1_k127_3345760_18 PFAM BNR Asp-box repeat - - - 0.000000000000000000000005518 121.0
HFD1_k127_3345760_19 transmembrane transporter activity - - - 0.0000003744 57.0
HFD1_k127_3345760_2 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 574.0
HFD1_k127_3345760_3 Aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 514.0
HFD1_k127_3345760_4 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 483.0
HFD1_k127_3345760_5 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 404.0
HFD1_k127_3345760_6 SAF K01685 - 4.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 395.0
HFD1_k127_3345760_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 361.0
HFD1_k127_3345760_8 glucosamine-6-phosphate deaminase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 347.0
HFD1_k127_3345760_9 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 383.0
HFD1_k127_3366154_0 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 314.0
HFD1_k127_3366154_1 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 299.0
HFD1_k127_3451741_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.044e-269 853.0
HFD1_k127_3451741_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.297e-194 618.0
HFD1_k127_3451741_10 DinB superfamily - - - 0.0000000000000000000000000000000000004438 146.0
HFD1_k127_3451741_11 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 - - 0.000000000000000000000000000000007362 141.0
HFD1_k127_3451741_12 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000006962 131.0
HFD1_k127_3451741_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000004383 122.0
HFD1_k127_3451741_14 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000001282 110.0
HFD1_k127_3451741_15 - - - - 0.000000000000000000000003176 103.0
HFD1_k127_3451741_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000004846 102.0
HFD1_k127_3451741_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.00000000000000000008997 94.0
HFD1_k127_3451741_18 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000001033 93.0
HFD1_k127_3451741_19 - - - - 0.0000000000006314 78.0
HFD1_k127_3451741_2 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 454.0
HFD1_k127_3451741_20 CsbD-like - - - 0.0000000001154 64.0
HFD1_k127_3451741_21 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.000000001418 74.0
HFD1_k127_3451741_22 Resolvase, N terminal domain - - - 0.000008758 48.0
HFD1_k127_3451741_23 amine dehydrogenase activity K01179,K01406,K07004 - 3.2.1.4,3.4.24.40 0.00001593 60.0
HFD1_k127_3451741_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 372.0
HFD1_k127_3451741_4 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 312.0
HFD1_k127_3451741_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 273.0
HFD1_k127_3451741_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000005639 250.0
HFD1_k127_3451741_7 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000002649 176.0
HFD1_k127_3451741_8 Cation transport regulator - - - 0.00000000000000000000000000000000000000000000003355 175.0
HFD1_k127_3460418_0 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 332.0
HFD1_k127_3460418_1 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 313.0
HFD1_k127_3460418_2 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate - - - 0.00000000000000000000000000000000000000000000000000000000000000000004139 249.0
HFD1_k127_3460418_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000003332 144.0
HFD1_k127_3460418_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000004986 123.0
HFD1_k127_3460418_5 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000001411 56.0
HFD1_k127_3460418_6 2OG-Fe(II) oxygenase superfamily K15429 - 2.1.1.228 0.00000003414 64.0
HFD1_k127_3476258_0 4Fe-4S dicluster domain K00184 - - 3.794e-275 878.0
HFD1_k127_3476258_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 462.0
HFD1_k127_3476258_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000003419 74.0
HFD1_k127_3491163_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 5.388e-253 795.0
HFD1_k127_3491163_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.223e-234 742.0
HFD1_k127_3491163_10 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 310.0
HFD1_k127_3491163_11 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000507 286.0
HFD1_k127_3491163_12 Phosphomethylpyrimidine kinase K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000001338 206.0
HFD1_k127_3491163_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001868 222.0
HFD1_k127_3491163_14 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000001671 196.0
HFD1_k127_3491163_15 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000251 186.0
HFD1_k127_3491163_16 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001173 181.0
HFD1_k127_3491163_17 BON domain - - - 0.000000000000000000000000000000000000000000008755 171.0
HFD1_k127_3491163_18 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000005806 166.0
HFD1_k127_3491163_19 CHRD domain - - - 0.0000000000000000000000000000000000001252 149.0
HFD1_k127_3491163_2 acyl-CoA dehydrogenase activity K09456 - - 2.938e-229 722.0
HFD1_k127_3491163_20 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000003473 156.0
HFD1_k127_3491163_21 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000001723 141.0
HFD1_k127_3491163_22 acetylesterase activity - - - 0.000000000000000000000000000001996 136.0
HFD1_k127_3491163_23 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000002033 124.0
HFD1_k127_3491163_24 diguanylate cyclase - - - 0.00000000000000000000001997 114.0
HFD1_k127_3491163_25 -O-antigen - - - 0.000004541 59.0
HFD1_k127_3491163_27 Ankyrin repeat - - - 0.00001328 57.0
HFD1_k127_3491163_3 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 4.19e-207 653.0
HFD1_k127_3491163_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.773e-197 629.0
HFD1_k127_3491163_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 542.0
HFD1_k127_3491163_6 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 508.0
HFD1_k127_3491163_7 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 484.0
HFD1_k127_3491163_8 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 403.0
HFD1_k127_3491163_9 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 337.0
HFD1_k127_3491534_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 582.0
HFD1_k127_3491534_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 522.0
HFD1_k127_3491534_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000007785 183.0
HFD1_k127_3491534_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000002008 181.0
HFD1_k127_3491534_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000002403 173.0
HFD1_k127_3491534_13 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000004301 166.0
HFD1_k127_3491534_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000008557 155.0
HFD1_k127_3491534_15 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000001129 148.0
HFD1_k127_3491534_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000004427 125.0
HFD1_k127_3491534_17 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001809 114.0
HFD1_k127_3491534_18 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000895 115.0
HFD1_k127_3491534_19 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000001891 116.0
HFD1_k127_3491534_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 474.0
HFD1_k127_3491534_20 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006383 107.0
HFD1_k127_3491534_21 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000006507 98.0
HFD1_k127_3491534_22 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001844 94.0
HFD1_k127_3491534_23 Ribosomal protein L30 K02907 - - 0.0000000000000002777 80.0
HFD1_k127_3491534_24 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000005482 74.0
HFD1_k127_3491534_25 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000006379 50.0
HFD1_k127_3491534_3 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 319.0
HFD1_k127_3491534_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
HFD1_k127_3491534_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001703 252.0
HFD1_k127_3491534_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000002796 218.0
HFD1_k127_3491534_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000001502 218.0
HFD1_k127_3491534_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000003224 196.0
HFD1_k127_3491534_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000005946 183.0
HFD1_k127_3491736_0 Elongation factor G, domain IV K02355 - - 4.395e-227 726.0
HFD1_k127_3491736_1 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000009186 210.0
HFD1_k127_3491736_2 - - - - 0.00000000000000000000000000000000000000000000000000000005172 209.0
HFD1_k127_3491736_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000009029 183.0
HFD1_k127_3491736_4 - - - - 0.0000000000000000000000007894 114.0
HFD1_k127_3491736_6 COGs COG0058 Glucan phosphorylase K00688,K00691,K16153 - 2.4.1.1,2.4.1.11,2.4.1.8 0.00002135 48.0
HFD1_k127_349628_0 Tricorn protease homolog K08676 - - 0.0 1499.0
HFD1_k127_349628_1 Peptidase M61 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 503.0
HFD1_k127_349628_10 Glycosyltransferase Family 4 - - - 0.00000000000000000000000003336 123.0
HFD1_k127_349628_11 triphosphatase activity - - - 0.00000000000000000000000354 109.0
HFD1_k127_349628_12 Protein of unknown function (DUF3298) - - - 0.00000000000000000000003095 113.0
HFD1_k127_349628_13 DoxX K15977 - - 0.000000000000000000003052 98.0
HFD1_k127_349628_14 Polymer-forming cytoskeletal - - - 0.0000002918 57.0
HFD1_k127_349628_15 Cyclase dehydrase - - - 0.0000143 51.0
HFD1_k127_349628_16 Tetratricopeptide repeat - - - 0.00001818 50.0
HFD1_k127_349628_2 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 412.0
HFD1_k127_349628_3 MFS_1 like family K08151,K08153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002067 287.0
HFD1_k127_349628_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001396 275.0
HFD1_k127_349628_5 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000009388 263.0
HFD1_k127_349628_6 Enoyl-CoA hydratase/isomerase K01715,K13767 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000001827 230.0
HFD1_k127_349628_7 transferase activity, transferring glycosyl groups K07011 - - 0.00000000000000000000000000000000000000000000000000001437 204.0
HFD1_k127_349628_8 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000001109 190.0
HFD1_k127_349628_9 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000229 140.0
HFD1_k127_3549043_0 efflux transmembrane transporter activity K02004 - - 1.729e-198 645.0
HFD1_k127_3549043_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000008939 105.0
HFD1_k127_3549043_2 efflux transmembrane transporter activity - - - 0.000000000000000000000005223 105.0
HFD1_k127_3556477_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 3.565e-283 884.0
HFD1_k127_3556477_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 611.0
HFD1_k127_3556477_10 Family of unknown function (DUF5339) - - - 0.000000000004315 72.0
HFD1_k127_3556477_11 Nacht domain - - - 0.000000006673 68.0
HFD1_k127_3556477_12 Tetratricopeptide repeat - - - 0.00007521 51.0
HFD1_k127_3556477_13 Putative zinc-finger - - - 0.0006586 51.0
HFD1_k127_3556477_2 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 484.0
HFD1_k127_3556477_3 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 409.0
HFD1_k127_3556477_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 299.0
HFD1_k127_3556477_5 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000003005 203.0
HFD1_k127_3556477_6 DinB family - - - 0.0000000000000000000000000000000000000000000002212 172.0
HFD1_k127_3556477_7 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000009561 165.0
HFD1_k127_3556477_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000001674 136.0
HFD1_k127_3556477_9 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000001454 127.0
HFD1_k127_3596194_0 PFAM Type II secretion system protein E K02652 - - 1.48e-216 685.0
HFD1_k127_3596194_1 Carboxypeptidase regulatory-like domain - - - 1.273e-205 677.0
HFD1_k127_3596194_10 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000155 183.0
HFD1_k127_3596194_11 Low affinity iron permease - - - 0.0000000000000000000000000000000000000000000005242 173.0
HFD1_k127_3596194_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000003126 158.0
HFD1_k127_3596194_13 ECF sigma factor K03088 - - 0.000000000000000000000000000000000002207 145.0
HFD1_k127_3596194_14 type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000001101 154.0
HFD1_k127_3596194_15 - - - - 0.000000000000000000000000000000005402 132.0
HFD1_k127_3596194_16 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.00000000000000000000000000002471 119.0
HFD1_k127_3596194_17 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000001503 123.0
HFD1_k127_3596194_18 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000001509 119.0
HFD1_k127_3596194_19 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000000000464 112.0
HFD1_k127_3596194_2 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 561.0
HFD1_k127_3596194_20 Belongs to the UPF0237 family K07166 - - 0.0000000000000000005795 92.0
HFD1_k127_3596194_21 Pilus assembly protein - - - 0.00000004398 64.0
HFD1_k127_3596194_22 Peptidase M16 inactive domain - - - 0.000004737 57.0
HFD1_k127_3596194_23 Anti-sigma K factor RskA - - - 0.0001334 52.0
HFD1_k127_3596194_3 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 398.0
HFD1_k127_3596194_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 304.0
HFD1_k127_3596194_5 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006195 267.0
HFD1_k127_3596194_6 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000002731 241.0
HFD1_k127_3596194_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000003446 225.0
HFD1_k127_3596194_8 Participates in transcription elongation, termination and antitermination - - - 0.0000000000000000000000000000000000000000000000000000000000001562 228.0
HFD1_k127_3596194_9 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000001178 189.0
HFD1_k127_3619002_0 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 344.0
HFD1_k127_3619002_1 PFAM Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.00000000000000000007387 94.0
HFD1_k127_3637164_0 Sortilin, neurotensin receptor 3, - - - 0.0 1423.0
HFD1_k127_3637164_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 411.0
HFD1_k127_3637164_2 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 398.0
HFD1_k127_3637164_3 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 396.0
HFD1_k127_3637164_4 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 294.0
HFD1_k127_3637164_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000001094 190.0
HFD1_k127_3637164_6 amino acid K03294 - - 0.00000000000000000000000000000000000000000001781 168.0
HFD1_k127_3637164_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000004704 162.0
HFD1_k127_3637164_8 Universal stress protein family - - - 0.000000000000006917 81.0
HFD1_k127_364462_0 cellulose binding - - - 1.591e-294 937.0
HFD1_k127_364462_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.288e-230 723.0
HFD1_k127_364462_2 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 2.814e-229 722.0
HFD1_k127_364462_3 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 377.0
HFD1_k127_364462_4 polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 325.0
HFD1_k127_364462_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 310.0
HFD1_k127_364462_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000008533 253.0
HFD1_k127_364462_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000003507 219.0
HFD1_k127_364462_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000001729 123.0
HFD1_k127_364462_9 TIGRFAM TonB - - - 0.0000002557 61.0
HFD1_k127_3649944_0 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 588.0
HFD1_k127_3649944_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 414.0
HFD1_k127_3649944_10 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000002434 209.0
HFD1_k127_3649944_11 HisG, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000005376 203.0
HFD1_k127_3649944_12 oxidoreductase activity, acting on CH-OH group of donors K13237 - 1.3.1.34 0.00000000000000000000000000000000000000000000000006758 182.0
HFD1_k127_3649944_13 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000001173 111.0
HFD1_k127_3649944_14 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000007307 77.0
HFD1_k127_3649944_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 353.0
HFD1_k127_3649944_3 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 296.0
HFD1_k127_3649944_4 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 301.0
HFD1_k127_3649944_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000002929 255.0
HFD1_k127_3649944_6 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000002072 247.0
HFD1_k127_3649944_7 Histidine biosynthesis protein K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000001232 241.0
HFD1_k127_3649944_8 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000003485 231.0
HFD1_k127_3649944_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000001567 216.0
HFD1_k127_3708392_0 Tetratricopeptide repeat - - - 9.341e-221 722.0
HFD1_k127_3708392_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 497.0
HFD1_k127_3708392_10 TIR domain - - - 0.0000000000000000000000025 115.0
HFD1_k127_3708392_2 amino acid peptide transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 486.0
HFD1_k127_3708392_3 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 471.0
HFD1_k127_3708392_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000009134 284.0
HFD1_k127_3708392_5 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000002325 222.0
HFD1_k127_3708392_6 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.00000000000000000000000000000000000000000000000000000000009073 209.0
HFD1_k127_3708392_7 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000004272 203.0
HFD1_k127_3708392_8 Adenylate cyclase - - - 0.00000000000000000000000000000332 140.0
HFD1_k127_3708392_9 von Willebrand factor, type A K07114,K12511 - - 0.00000000000000000000000001189 124.0
HFD1_k127_3733342_0 penicillin-binding protein - - - 0.000000000000000000000000000000000000000000000000000003175 211.0
HFD1_k127_3740131_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1293.0
HFD1_k127_3740131_1 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 554.0
HFD1_k127_3740131_2 Class II aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 368.0
HFD1_k127_3740131_3 PFAM Isochorismatase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000004838 203.0
HFD1_k127_3740131_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000001439 155.0
HFD1_k127_3740131_5 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000003519 143.0
HFD1_k127_3768206_0 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 463.0
HFD1_k127_3768206_1 NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001556 276.0
HFD1_k127_3768206_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000005382 164.0
HFD1_k127_3799724_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 531.0
HFD1_k127_3799724_1 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 390.0
HFD1_k127_3799724_10 - - - - 0.00004455 53.0
HFD1_k127_3799724_11 VWA domain containing CoxE-like protein - - - 0.0001084 54.0
HFD1_k127_3799724_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000002477 220.0
HFD1_k127_3799724_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000423 176.0
HFD1_k127_3799724_4 Domain of unknown function (DUF4252) - - - 0.00000000000000000000000000000000000000003346 159.0
HFD1_k127_3799724_5 Radical SAM K22227 - - 0.00000000000000000000000000000000000001611 158.0
HFD1_k127_3799724_6 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000008421 142.0
HFD1_k127_3799724_7 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000003734 136.0
HFD1_k127_3799724_8 multi-organism process K03195 - - 0.00000000000004722 84.0
HFD1_k127_380763_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 609.0
HFD1_k127_380763_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 486.0
HFD1_k127_380763_10 PFAM Peptidase M20 - - - 0.0000000000000000000000000000000000000000000000000000001295 211.0
HFD1_k127_380763_11 Protein of unknown function (DUF2752) - - - 0.0000000000000000000000004 111.0
HFD1_k127_380763_12 O-Antigen ligase K18814 - - 0.000000000000000000006166 107.0
HFD1_k127_380763_2 RmlD substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 428.0
HFD1_k127_380763_3 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 429.0
HFD1_k127_380763_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 368.0
HFD1_k127_380763_5 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 311.0
HFD1_k127_380763_6 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 302.0
HFD1_k127_380763_7 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001944 246.0
HFD1_k127_380763_8 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000000000000000000000000001609 245.0
HFD1_k127_380763_9 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000023 226.0
HFD1_k127_3809545_0 hydrolase, family 3 K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 589.0
HFD1_k127_3809545_1 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 590.0
HFD1_k127_3809545_10 heat shock protein binding - - - 0.0004274 52.0
HFD1_k127_3809545_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 554.0
HFD1_k127_3809545_3 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 445.0
HFD1_k127_3809545_4 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 429.0
HFD1_k127_3809545_5 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 413.0
HFD1_k127_3809545_6 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000000002789 182.0
HFD1_k127_3809545_7 - - - - 0.000000000000000000000000000000000001163 158.0
HFD1_k127_3809545_8 12 heme-binding sites - - - 0.00000000000000000004145 102.0
HFD1_k127_3809545_9 Class III cytochrome C family - - - 0.00001672 54.0
HFD1_k127_383774_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 458.0
HFD1_k127_383774_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 399.0
HFD1_k127_383774_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000004189 196.0
HFD1_k127_383774_11 Helix-turn-helix domain K03088 - - 0.000000000000000000000000000004923 127.0
HFD1_k127_383774_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008706 367.0
HFD1_k127_383774_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 356.0
HFD1_k127_383774_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 338.0
HFD1_k127_383774_5 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 345.0
HFD1_k127_383774_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 302.0
HFD1_k127_383774_7 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000396 237.0
HFD1_k127_383774_8 Bacteriocin-protection protein - - - 0.00000000000000000000000000000000000000000000000000000000009584 213.0
HFD1_k127_383774_9 -acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000003528 198.0
HFD1_k127_3870084_0 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000003414 179.0
HFD1_k127_3870084_1 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000342 164.0
HFD1_k127_3870084_2 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.00000000000000004218 93.0
HFD1_k127_387516_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 413.0
HFD1_k127_387516_1 Transporter-associated region K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 394.0
HFD1_k127_387516_10 domain protein K14194 - - 0.000000000005806 79.0
HFD1_k127_387516_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003703 297.0
HFD1_k127_387516_3 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001381 261.0
HFD1_k127_387516_4 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000001679 241.0
HFD1_k127_387516_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000008837 214.0
HFD1_k127_387516_6 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000001054 198.0
HFD1_k127_387516_7 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000001708 150.0
HFD1_k127_387516_8 YbbR-like protein - - - 0.00000000000000000004666 102.0
HFD1_k127_387516_9 domain protein - - - 0.00000000000000002347 96.0
HFD1_k127_3884823_0 - K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 462.0
HFD1_k127_3884823_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 357.0
HFD1_k127_3894041_0 Flagellar Assembly Protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000003673 228.0
HFD1_k127_3894041_1 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000002017 212.0
HFD1_k127_3894041_2 Phage tail sheath protein subtilisin-like domain - - - 0.000000000000000000000000000000000000000000000000002332 186.0
HFD1_k127_3901258_0 Cytochrome c - - - 9.719e-298 944.0
HFD1_k127_3901258_1 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 4.264e-197 632.0
HFD1_k127_3901258_10 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000003711 119.0
HFD1_k127_3901258_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 298.0
HFD1_k127_3901258_3 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002868 264.0
HFD1_k127_3901258_4 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
HFD1_k127_3901258_5 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000379 204.0
HFD1_k127_3901258_6 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.00000000000000000000000000000000000000000001814 168.0
HFD1_k127_3901258_7 heme a metabolic process K02259,K03110 - - 0.00000000000000000000000000000000000000002001 165.0
HFD1_k127_3901258_8 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000000013 151.0
HFD1_k127_3901258_9 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000005669 128.0
HFD1_k127_3926036_0 PrkA AAA domain protein K07180 - - 9.408e-306 948.0
HFD1_k127_3926036_1 SpoVR like protein K06415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 561.0
HFD1_k127_3926036_2 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 487.0
HFD1_k127_3926036_3 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002086 281.0
HFD1_k127_3926036_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000006378 229.0
HFD1_k127_3926036_5 typically periplasmic contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000003803 199.0
HFD1_k127_3926036_6 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000003127 162.0
HFD1_k127_3926036_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000001224 72.0
HFD1_k127_3931592_0 Acyclic terpene utilisation family protein AtuA - - - 7.543e-214 671.0
HFD1_k127_3931592_1 efflux transmembrane transporter activity K02004 - - 7.237e-200 652.0
HFD1_k127_3931592_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 602.0
HFD1_k127_3931592_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 541.0
HFD1_k127_3931592_4 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 539.0
HFD1_k127_3931592_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 527.0
HFD1_k127_3931592_6 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 453.0
HFD1_k127_3931592_7 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 417.0
HFD1_k127_3931592_8 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 400.0
HFD1_k127_3931592_9 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 417.0
HFD1_k127_3951927_0 metallocarboxypeptidase activity K14054 - - 1.075e-285 910.0
HFD1_k127_3951927_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 472.0
HFD1_k127_3951927_2 Protein of unknown function, DUF480 K09915 - - 0.00000000000005627 72.0
HFD1_k127_3996155_0 radical SAM domain protein - - - 3.284e-288 894.0
HFD1_k127_3996155_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 623.0
HFD1_k127_3996155_10 - - - - 0.0000000000000000000000000000000000000000000002489 175.0
HFD1_k127_3996155_11 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000003135 164.0
HFD1_k127_3996155_12 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000192 168.0
HFD1_k127_3996155_14 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000001503 134.0
HFD1_k127_3996155_15 peptidase inhibitor activity - - - 0.000000000000000000000000007021 123.0
HFD1_k127_3996155_16 - - - - 0.0000000000000000005992 96.0
HFD1_k127_3996155_17 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000002514 77.0
HFD1_k127_3996155_2 tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 532.0
HFD1_k127_3996155_3 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 461.0
HFD1_k127_3996155_4 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 393.0
HFD1_k127_3996155_5 Peptidase m28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 391.0
HFD1_k127_3996155_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 298.0
HFD1_k127_3996155_7 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000005475 238.0
HFD1_k127_3996155_8 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000001409 229.0
HFD1_k127_3996155_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002889 216.0
HFD1_k127_4022179_0 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 508.0
HFD1_k127_4022179_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 489.0
HFD1_k127_4022179_10 RTX toxins and related Ca2 binding proteins - - - 0.000000000000000000000000001511 132.0
HFD1_k127_4022179_11 Protein of unknown function (DUF3455) - - - 0.00000000000000000000001311 110.0
HFD1_k127_4022179_12 Methyltransferase domain - - - 0.0000000000000000000004519 112.0
HFD1_k127_4022179_13 MerR HTH family regulatory protein - - - 0.0000000000000003432 87.0
HFD1_k127_4022179_14 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.0000000000001274 84.0
HFD1_k127_4022179_2 Belongs to the heat shock protein 70 family K04046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 396.0
HFD1_k127_4022179_3 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 331.0
HFD1_k127_4022179_4 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 299.0
HFD1_k127_4022179_6 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000007391 220.0
HFD1_k127_4022179_7 RTX toxins and related Ca2 binding proteins - - - 0.00000000000000000000000000000000000000000000001764 197.0
HFD1_k127_404225_0 A-macroglobulin complement component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 662.0
HFD1_k127_404225_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 553.0
HFD1_k127_404225_2 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 476.0
HFD1_k127_404225_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 438.0
HFD1_k127_404225_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 365.0
HFD1_k127_404225_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 252.0
HFD1_k127_404225_6 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000000042 177.0
HFD1_k127_404225_7 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000009272 170.0
HFD1_k127_4044134_0 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 496.0
HFD1_k127_4044134_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 381.0
HFD1_k127_4044134_2 Peptidase family M28 - - - 0.00000000000000000000000001899 109.0
HFD1_k127_4060982_0 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.0 1424.0
HFD1_k127_4060982_1 transport - - - 0.0 1161.0
HFD1_k127_4060982_10 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 436.0
HFD1_k127_4060982_11 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 422.0
HFD1_k127_4060982_12 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 409.0
HFD1_k127_4060982_13 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 401.0
HFD1_k127_4060982_14 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 395.0
HFD1_k127_4060982_15 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 387.0
HFD1_k127_4060982_16 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 359.0
HFD1_k127_4060982_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 358.0
HFD1_k127_4060982_18 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 338.0
HFD1_k127_4060982_19 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 341.0
HFD1_k127_4060982_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.051e-229 718.0
HFD1_k127_4060982_20 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 326.0
HFD1_k127_4060982_21 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 312.0
HFD1_k127_4060982_22 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 299.0
HFD1_k127_4060982_23 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 295.0
HFD1_k127_4060982_24 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 292.0
HFD1_k127_4060982_25 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003506 282.0
HFD1_k127_4060982_26 HPr kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847 278.0
HFD1_k127_4060982_27 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000064 268.0
HFD1_k127_4060982_28 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001208 271.0
HFD1_k127_4060982_29 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000002008 206.0
HFD1_k127_4060982_3 ATPases associated with a variety of cellular activities K06147 - - 1.066e-204 655.0
HFD1_k127_4060982_30 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000167 209.0
HFD1_k127_4060982_31 Peptidase of plants and bacteria - - - 0.00000000000000000000000000000000000000000000000000001714 195.0
HFD1_k127_4060982_32 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000003374 165.0
HFD1_k127_4060982_33 - - - - 0.000000000000000000000000000000000000001527 158.0
HFD1_k127_4060982_34 LUD domain K00782 - - 0.0000000000000000000005898 104.0
HFD1_k127_4060982_35 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000007597 86.0
HFD1_k127_4060982_36 Protein of unknown function (DUF1326) - - - 0.00000000000000003005 91.0
HFD1_k127_4060982_4 ABC transporter K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 598.0
HFD1_k127_4060982_5 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 484.0
HFD1_k127_4060982_6 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 499.0
HFD1_k127_4060982_7 PFAM Alcohol dehydrogenase GroES-like domain K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 478.0
HFD1_k127_4060982_8 cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 468.0
HFD1_k127_4060982_9 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 459.0
HFD1_k127_4062748_0 Flavin containing amine oxidoreductase - - - 2.767e-292 904.0
HFD1_k127_4062748_1 Carboxypeptidase regulatory-like domain - - - 2.864e-248 801.0
HFD1_k127_4062748_10 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000002049 225.0
HFD1_k127_4062748_11 PhoQ Sensor K07640 - 2.7.13.3 0.000000000000000000000000000000000000000000008602 174.0
HFD1_k127_4062748_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 570.0
HFD1_k127_4062748_3 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 548.0
HFD1_k127_4062748_4 PFAM Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 469.0
HFD1_k127_4062748_5 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 442.0
HFD1_k127_4062748_6 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 431.0
HFD1_k127_4062748_7 amino acid K03294,K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 356.0
HFD1_k127_4062748_8 Transcriptional regulatory protein, C terminal K07662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 311.0
HFD1_k127_4062748_9 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006878 280.0
HFD1_k127_4072616_0 class II (D K K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 605.0
HFD1_k127_4072616_1 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 383.0
HFD1_k127_4072616_2 Belongs to the arginase family K01476 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 327.0
HFD1_k127_4072616_3 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 293.0
HFD1_k127_4072616_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003297 260.0
HFD1_k127_4072616_5 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000003304 156.0
HFD1_k127_4072616_6 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000001524 129.0
HFD1_k127_4072616_7 Nucleotide-diphospho-sugar transferase K03240 GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005851,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0019222,GO:0019538,GO:0019899,GO:0031323,GO:0031326,GO:0032045,GO:0032268,GO:0032991,GO:0034248,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051020,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0080090,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0001425 47.0
HFD1_k127_4080951_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.972e-311 965.0
HFD1_k127_4080951_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 452.0
HFD1_k127_4080951_10 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000002954 188.0
HFD1_k127_4080951_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000003161 181.0
HFD1_k127_4080951_12 Y_Y_Y domain - - - 0.0000000000000000000000000000000000000004191 173.0
HFD1_k127_4080951_13 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000006717 155.0
HFD1_k127_4080951_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001892 160.0
HFD1_k127_4080951_15 AI-2E family transporter - - - 0.00000000000000000000000000000000002699 151.0
HFD1_k127_4080951_16 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000004624 134.0
HFD1_k127_4080951_17 - catabolite gene activator and regulatory subunit of cAMP-dependent protein K10914 - - 0.0000000000000000000000154 109.0
HFD1_k127_4080951_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000004637 106.0
HFD1_k127_4080951_19 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000007999 82.0
HFD1_k127_4080951_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 440.0
HFD1_k127_4080951_20 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00002482 55.0
HFD1_k127_4080951_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 399.0
HFD1_k127_4080951_4 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 348.0
HFD1_k127_4080951_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 323.0
HFD1_k127_4080951_6 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
HFD1_k127_4080951_7 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001565 273.0
HFD1_k127_4080951_8 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000003743 205.0
HFD1_k127_4080951_9 PFAM Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000005307 200.0
HFD1_k127_4129981_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 6.88e-303 937.0
HFD1_k127_4129981_1 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 6.931e-294 923.0
HFD1_k127_4129981_2 Belongs to the glycosyl hydrolase 2 family K01190 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.23 1.721e-266 835.0
HFD1_k127_4129981_3 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 1.023e-260 828.0
HFD1_k127_4129981_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 465.0
HFD1_k127_4129981_5 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 380.0
HFD1_k127_4129981_6 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 297.0
HFD1_k127_4129981_7 Belongs to the glycosyl hydrolase 26 family - - - 0.000000000000001142 85.0
HFD1_k127_4147159_0 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 555.0
HFD1_k127_41502_0 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 3.156e-260 817.0
HFD1_k127_41502_1 protein conserved in bacteria K09955 - - 8.148e-259 820.0
HFD1_k127_41502_10 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 563.0
HFD1_k127_41502_11 Cellulase (glycosyl hydrolase family 5) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 522.0
HFD1_k127_41502_12 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 540.0
HFD1_k127_41502_13 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 484.0
HFD1_k127_41502_14 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 476.0
HFD1_k127_41502_15 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 469.0
HFD1_k127_41502_16 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 409.0
HFD1_k127_41502_17 inositol monophosphate 1-phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 432.0
HFD1_k127_41502_18 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 374.0
HFD1_k127_41502_19 Glycosyl hydrolases family 43 K06113 - 3.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 368.0
HFD1_k127_41502_2 carboxylic acid catabolic process K01187 - 3.2.1.20 4.091e-256 806.0
HFD1_k127_41502_20 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 317.0
HFD1_k127_41502_21 DNA-binding transcription factor activity K02081,K02444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 284.0
HFD1_k127_41502_22 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000009647 220.0
HFD1_k127_41502_23 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001817 181.0
HFD1_k127_41502_24 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000001358 155.0
HFD1_k127_41502_25 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000002652 165.0
HFD1_k127_41502_26 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000000004221 147.0
HFD1_k127_41502_27 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000001605 119.0
HFD1_k127_41502_28 iron ion binding - - - 0.000000000000000000000000493 111.0
HFD1_k127_41502_29 glycosyl transferase family 2 K20444 - - 0.0000000000000000001366 104.0
HFD1_k127_41502_3 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 2.266e-244 774.0
HFD1_k127_41502_30 Tetratricopeptide repeat - - - 0.000000001183 71.0
HFD1_k127_41502_31 Evidence 4 Homologs of previously reported genes of K03975 - - 0.000000005262 59.0
HFD1_k127_41502_32 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000007742 54.0
HFD1_k127_41502_4 PFAM carbohydrate kinase K00854 - 2.7.1.17 1.089e-218 688.0
HFD1_k127_41502_5 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 7.987e-215 679.0
HFD1_k127_41502_6 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 611.0
HFD1_k127_41502_7 PFAM Alcohol dehydrogenase K12957,K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 593.0
HFD1_k127_41502_8 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 598.0
HFD1_k127_41502_9 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 564.0
HFD1_k127_4160770_0 Heat shock 70 kDa protein K04043 - - 3.985e-292 908.0
HFD1_k127_4160770_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 402.0
HFD1_k127_4160770_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 387.0
HFD1_k127_4160770_3 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000005649 192.0
HFD1_k127_4160770_4 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000000009501 142.0
HFD1_k127_4160770_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.000000000000000000000000000008475 126.0
HFD1_k127_4160770_6 TonB dependent receptor K02014 - - 0.000000000002557 74.0
HFD1_k127_4160770_7 Peptidase M16 inactive domain - - - 0.000000000008519 74.0
HFD1_k127_4164443_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 483.0
HFD1_k127_4164443_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 473.0
HFD1_k127_4164443_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 414.0
HFD1_k127_4164443_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 318.0
HFD1_k127_4164443_4 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004821 267.0
HFD1_k127_4164443_5 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000007712 245.0
HFD1_k127_4164443_6 domain protein K02238 - - 0.000000000000000000000000000000000000000000000000007349 193.0
HFD1_k127_4164443_7 RDD family - - - 0.00000000000000000000000000000000000000001834 164.0
HFD1_k127_4176508_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 3.898e-252 790.0
HFD1_k127_4176508_1 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000000000000000000000000000021 137.0
HFD1_k127_4176508_2 - - - - 0.000341 52.0
HFD1_k127_4185944_0 PLD-like domain K06131 - - 1.022e-218 689.0
HFD1_k127_4185944_1 PBS lyase HEAT-like repeat - - - 5.153e-212 680.0
HFD1_k127_4185944_10 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000001375 141.0
HFD1_k127_4185944_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 597.0
HFD1_k127_4185944_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 534.0
HFD1_k127_4185944_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 486.0
HFD1_k127_4185944_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 469.0
HFD1_k127_4185944_6 Methyltransferase, chemotaxis proteins K00575,K13486 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 325.0
HFD1_k127_4185944_7 CheC inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001597 247.0
HFD1_k127_4185944_8 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005577 237.0
HFD1_k127_4185944_9 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000004744 188.0
HFD1_k127_4198584_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1025.0
HFD1_k127_4198584_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 3.663e-277 862.0
HFD1_k127_4198584_10 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.00000000000001008 75.0
HFD1_k127_4198584_2 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 440.0
HFD1_k127_4198584_3 nitrite transmembrane transporter activity K02575,K10850 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
HFD1_k127_4198584_4 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 333.0
HFD1_k127_4198584_5 response regulator, receiver K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 299.0
HFD1_k127_4198584_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002986 270.0
HFD1_k127_4198584_7 Domain of Unknown function (DUF542) K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005438 244.0
HFD1_k127_4198584_9 Histidine kinase - - - 0.000000000000000000000004073 108.0
HFD1_k127_4199986_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 4.46e-301 940.0
HFD1_k127_4199986_1 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 1.424e-207 659.0
HFD1_k127_4199986_10 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000001446 184.0
HFD1_k127_4199986_11 peptidase M15B and M15C DD-carboxypeptidase VanY - - - 0.0000000000000000000006729 107.0
HFD1_k127_4199986_12 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000003355 74.0
HFD1_k127_4199986_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07027 - - 0.0000000007859 70.0
HFD1_k127_4199986_14 Belongs to the ompA family - - - 0.00002951 55.0
HFD1_k127_4199986_2 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 552.0
HFD1_k127_4199986_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 427.0
HFD1_k127_4199986_4 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 399.0
HFD1_k127_4199986_5 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 338.0
HFD1_k127_4199986_6 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 317.0
HFD1_k127_4199986_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
HFD1_k127_4199986_8 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000002455 220.0
HFD1_k127_4199986_9 Serine threonine protein K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000002939 216.0
HFD1_k127_4200548_0 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000002279 190.0
HFD1_k127_4200548_1 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000002865 104.0
HFD1_k127_4200548_2 TadE-like protein - - - 0.0000000000004797 76.0
HFD1_k127_4200548_3 TadE-like protein - - - 0.000000000003044 74.0
HFD1_k127_4208231_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1189.0
HFD1_k127_4208231_1 4Fe-4S dicluster domain K07307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 328.0
HFD1_k127_4208231_2 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000002939 179.0
HFD1_k127_4224847_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 1.672e-286 897.0
HFD1_k127_4224847_1 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 300.0
HFD1_k127_4224847_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
HFD1_k127_4224847_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000001429 107.0
HFD1_k127_4224847_4 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.0000000000000298 79.0
HFD1_k127_4245260_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 567.0
HFD1_k127_4245260_1 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 506.0
HFD1_k127_4245260_2 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007814 279.0
HFD1_k127_4245260_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000002153 241.0
HFD1_k127_4245260_4 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000002652 89.0
HFD1_k127_426403_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 439.0
HFD1_k127_426403_1 Phage late control gene D protein (GPD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 423.0
HFD1_k127_426403_2 protein and some similarities with VgrG protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 388.0
HFD1_k127_4268547_0 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000142 199.0
HFD1_k127_4268547_1 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.0000000000000000000000000000000000000000000001135 175.0
HFD1_k127_4268547_2 Calx-beta domain - - - 0.000000000000000000000000000000000000001207 163.0
HFD1_k127_4274270_0 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 490.0
HFD1_k127_4274270_1 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 475.0
HFD1_k127_4274270_2 - - - - 0.00000000000003517 76.0
HFD1_k127_4288031_0 PFAM Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 558.0
HFD1_k127_4288031_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 563.0
HFD1_k127_4288031_10 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000002229 210.0
HFD1_k127_4288031_11 - - - - 0.000000000000000000000000000000000000000000007359 184.0
HFD1_k127_4288031_12 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000003756 170.0
HFD1_k127_4288031_15 Transcriptional repressor, CopY family - - - 0.000000000000000000000000000000000003709 140.0
HFD1_k127_4288031_16 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000009237 124.0
HFD1_k127_4288031_18 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000007284 70.0
HFD1_k127_4288031_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 466.0
HFD1_k127_4288031_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 423.0
HFD1_k127_4288031_4 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 353.0
HFD1_k127_4288031_5 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 299.0
HFD1_k127_4288031_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009298 260.0
HFD1_k127_4288031_7 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000004565 248.0
HFD1_k127_4288031_8 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000001985 238.0
HFD1_k127_4288031_9 - - - - 0.0000000000000000000000000000000000000000000000000000000005718 211.0
HFD1_k127_4294983_0 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 558.0
HFD1_k127_4294983_1 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 444.0
HFD1_k127_4294983_2 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 333.0
HFD1_k127_4294983_3 Glycosyl hydrolase-like 10 - - - 0.0000000000001768 75.0
HFD1_k127_4304566_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 8.026e-201 632.0
HFD1_k127_4304566_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 543.0
HFD1_k127_4304566_2 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000001419 139.0
HFD1_k127_4304566_3 adenosylhomocysteinase activity K01251 - 3.3.1.1 0.000000006063 62.0
HFD1_k127_4333382_0 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 2.814e-206 654.0
HFD1_k127_4333382_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 484.0
HFD1_k127_4333382_10 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.000000000000000000000000000000003519 141.0
HFD1_k127_4333382_11 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000000000000001336 100.0
HFD1_k127_4333382_12 Putative restriction endonuclease - - - 0.00000000000000000003365 97.0
HFD1_k127_4333382_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 471.0
HFD1_k127_4333382_3 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004334 259.0
HFD1_k127_4333382_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001537 244.0
HFD1_k127_4333382_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000002473 216.0
HFD1_k127_4333382_6 spore germination - - - 0.000000000000000000000000000000000000000000000000000000004857 209.0
HFD1_k127_4333382_7 - - - - 0.00000000000000000000000000000000000000000000000002377 187.0
HFD1_k127_4333382_8 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.00000000000000000000000000000000000000007807 159.0
HFD1_k127_4333382_9 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000001005 151.0
HFD1_k127_4340275_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 409.0
HFD1_k127_4340275_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 300.0
HFD1_k127_4340275_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006148 263.0
HFD1_k127_4340275_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000003282 137.0
HFD1_k127_4361736_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1341.0
HFD1_k127_4361736_1 cellulose binding - - - 7.512e-219 683.0
HFD1_k127_4361736_10 GrpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004046 230.0
HFD1_k127_4361736_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000002511 148.0
HFD1_k127_4361736_12 Ami_2 - - - 0.00000000000000000001223 93.0
HFD1_k127_4361736_13 Protein conserved in bacteria - - - 0.00000000000005947 74.0
HFD1_k127_4361736_14 Bacterial regulatory proteins, tetR family - - - 0.0000000000006277 76.0
HFD1_k127_4361736_15 Sporulation and spore germination - - - 0.0000001343 59.0
HFD1_k127_4361736_2 Conserved protein K09704 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 574.0
HFD1_k127_4361736_3 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 463.0
HFD1_k127_4361736_4 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 374.0
HFD1_k127_4361736_5 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 355.0
HFD1_k127_4361736_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 341.0
HFD1_k127_4361736_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 310.0
HFD1_k127_4361736_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000001338 244.0
HFD1_k127_4361736_9 KWG Leptospira - - - 0.000000000000000000000000000000000000000000000000000000000000000002843 240.0
HFD1_k127_4363382_0 cellulose binding - - - 9.358e-299 943.0
HFD1_k127_4440796_0 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 578.0
HFD1_k127_4440796_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 517.0
HFD1_k127_4440796_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 482.0
HFD1_k127_4440796_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000004458 256.0
HFD1_k127_4440796_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000002461 199.0
HFD1_k127_4440796_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.0000000000851 74.0
HFD1_k127_4452642_0 PFAM NHL repeat - - - 1.295e-200 647.0
HFD1_k127_4452642_1 PFAM Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 596.0
HFD1_k127_4452642_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000004854 157.0
HFD1_k127_4452642_11 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000001266 135.0
HFD1_k127_4452642_12 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000141 139.0
HFD1_k127_4452642_13 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000966 130.0
HFD1_k127_4452642_14 Phosphoglycerate mutase family - - - 0.00000000000000000000000001432 117.0
HFD1_k127_4452642_15 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.00001025 51.0
HFD1_k127_4452642_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 511.0
HFD1_k127_4452642_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 505.0
HFD1_k127_4452642_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 419.0
HFD1_k127_4452642_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 412.0
HFD1_k127_4452642_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 357.0
HFD1_k127_4452642_7 Ferritin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 285.0
HFD1_k127_4452642_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009337 278.0
HFD1_k127_4452642_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000663 203.0
HFD1_k127_4452673_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 4.647e-227 719.0
HFD1_k127_4452673_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 559.0
HFD1_k127_4452673_2 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 398.0
HFD1_k127_4457563_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 498.0
HFD1_k127_4457563_1 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 383.0
HFD1_k127_4457563_2 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 306.0
HFD1_k127_4457563_3 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004023 282.0
HFD1_k127_4457563_4 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000002482 188.0
HFD1_k127_4457563_5 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000757 164.0
HFD1_k127_4464677_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 612.0
HFD1_k127_4464677_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 576.0
HFD1_k127_4464677_10 phosphorelay signal transduction system - - - 0.00000003167 64.0
HFD1_k127_4464677_11 self proteolysis - - - 0.00002351 56.0
HFD1_k127_4464677_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 479.0
HFD1_k127_4464677_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 359.0
HFD1_k127_4464677_4 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000154 230.0
HFD1_k127_4464677_5 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000000000000000000000000000002601 136.0
HFD1_k127_4464677_6 Protein of unknown function DUF84 - - - 0.0000000000005399 77.0
HFD1_k127_4464677_7 Tetratricopeptide repeat - - - 0.000000000005174 78.0
HFD1_k127_4464677_8 Tetratricopeptide repeat - - - 0.0000000003748 71.0
HFD1_k127_4464677_9 Transporter-associated region K03699 - - 0.00000002966 57.0
HFD1_k127_4464697_0 TonB-dependent receptor - - - 8.754e-229 743.0
HFD1_k127_4464697_1 LacI family K02529 - - 0.0000000000000000000000007858 108.0
HFD1_k127_4464697_2 Putative glucoamylase - - - 0.00000000000000000001124 94.0
HFD1_k127_44819_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 527.0
HFD1_k127_44819_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 412.0
HFD1_k127_44819_2 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004364 274.0
HFD1_k127_44819_3 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000000000003625 182.0
HFD1_k127_44819_4 Cytochrome c554 and c-prime - - - 0.0005851 52.0
HFD1_k127_4481989_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 383.0
HFD1_k127_4481989_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 321.0
HFD1_k127_4481989_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 318.0
HFD1_k127_4481989_3 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000005698 211.0
HFD1_k127_4481989_4 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000008362 182.0
HFD1_k127_4481989_5 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000001322 151.0
HFD1_k127_4481989_6 transcriptional regulator K03655 - 3.6.4.12 0.00000000000000000000000000000003911 141.0
HFD1_k127_4481989_7 - - - - 0.000000009407 68.0
HFD1_k127_4494427_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.805e-258 805.0
HFD1_k127_4494427_1 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 541.0
HFD1_k127_4494427_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 447.0
HFD1_k127_4494427_3 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 327.0
HFD1_k127_4494427_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000006816 185.0
HFD1_k127_4494427_5 PFAM Nickel cobalt transporter, high-affinity - - - 0.0000000000000000000000000000000000000000000000008053 183.0
HFD1_k127_4494427_6 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000000001277 175.0
HFD1_k127_4499917_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.255e-198 647.0
HFD1_k127_4499917_10 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.000000000000000000000000000000000000000000000000000002995 199.0
HFD1_k127_4499917_11 2OG-Fe(II) oxygenase superfamily K07336,K07394 - - 0.0000000000000000000000000000000009379 137.0
HFD1_k127_4499917_12 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.000000000000000000000000000001559 131.0
HFD1_k127_4499917_13 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000000000009824 124.0
HFD1_k127_4499917_14 Periplasmic binding protein K02016,K06858 - - 0.0000000000000000001942 92.0
HFD1_k127_4499917_15 Membrane - - - 0.0002185 50.0
HFD1_k127_4499917_2 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 569.0
HFD1_k127_4499917_3 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 456.0
HFD1_k127_4499917_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 430.0
HFD1_k127_4499917_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 401.0
HFD1_k127_4499917_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 374.0
HFD1_k127_4499917_7 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 358.0
HFD1_k127_4499917_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 331.0
HFD1_k127_4499917_9 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000005077 221.0
HFD1_k127_4503043_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1164.0
HFD1_k127_4503043_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 520.0
HFD1_k127_4503043_2 PFAM TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 400.0
HFD1_k127_4503043_3 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001281 210.0
HFD1_k127_4503043_4 - - - - 0.00000000000000000000000000007331 121.0
HFD1_k127_4503043_5 dienelactone hydrolase - - - 0.00000001373 58.0
HFD1_k127_4546625_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 3.704e-274 853.0
HFD1_k127_4546625_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 358.0
HFD1_k127_4547060_0 His Kinase A (phosphoacceptor) domain - - - 1.057e-208 677.0
HFD1_k127_4547060_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 524.0
HFD1_k127_4547060_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003123 271.0
HFD1_k127_4547060_11 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000007068 258.0
HFD1_k127_4547060_12 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002229 280.0
HFD1_k127_4547060_13 HNH endonuclease K07454 - - 0.00000000000000000000000000000000000000000000000000000000000000003335 228.0
HFD1_k127_4547060_15 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000003065 161.0
HFD1_k127_4547060_16 oxidoreductase activity - - - 0.00000000000000000000000000000000001702 156.0
HFD1_k127_4547060_17 heat shock protein DnaJ K05516 - - 0.000000000000000000000000000000001052 137.0
HFD1_k127_4547060_18 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000209 130.0
HFD1_k127_4547060_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 461.0
HFD1_k127_4547060_20 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000001561 106.0
HFD1_k127_4547060_21 cheY-homologous receiver domain - - - 0.00000000000000000000002095 104.0
HFD1_k127_4547060_22 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.00000000000000000000009373 106.0
HFD1_k127_4547060_23 transmembrane transporter activity - - - 0.00000000004353 69.0
HFD1_k127_4547060_24 regulation of methylation-dependent chromatin silencing K07454 - - 0.000001234 53.0
HFD1_k127_4547060_25 - - - - 0.00008059 54.0
HFD1_k127_4547060_3 Belongs to the proline racemase family K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 399.0
HFD1_k127_4547060_4 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 381.0
HFD1_k127_4547060_5 Hydrolase Family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 323.0
HFD1_k127_4547060_6 enterobactin catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 310.0
HFD1_k127_4547060_7 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 299.0
HFD1_k127_4547060_8 PFAM Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003994 280.0
HFD1_k127_4547060_9 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009175 275.0
HFD1_k127_4587288_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 413.0
HFD1_k127_4658603_0 domain protein - - - 0.0 1102.0
HFD1_k127_4658603_1 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 8.181e-220 691.0
HFD1_k127_4658603_10 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 294.0
HFD1_k127_4658603_11 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001872 289.0
HFD1_k127_4658603_12 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000003265 210.0
HFD1_k127_4658603_13 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000005904 201.0
HFD1_k127_4658603_14 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000000005665 174.0
HFD1_k127_4658603_15 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000005164 168.0
HFD1_k127_4658603_16 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.0000000000000000000000000000000000000001452 155.0
HFD1_k127_4658603_17 - - - - 0.000000000000000000000000000000000000002166 149.0
HFD1_k127_4658603_18 - - - - 0.00000000000000000000000000000000000001693 148.0
HFD1_k127_4658603_19 DinB superfamily K07552 - - 0.00000000000000000000000000000000000482 142.0
HFD1_k127_4658603_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 472.0
HFD1_k127_4658603_20 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000000704 132.0
HFD1_k127_4658603_21 - - - - 0.00000000000000000000004527 104.0
HFD1_k127_4658603_3 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 450.0
HFD1_k127_4658603_4 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 431.0
HFD1_k127_4658603_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 417.0
HFD1_k127_4658603_6 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 404.0
HFD1_k127_4658603_7 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 401.0
HFD1_k127_4658603_8 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 372.0
HFD1_k127_4658603_9 regulation of single-species biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 320.0
HFD1_k127_4675211_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1339.0
HFD1_k127_4675211_1 MFS/sugar transport protein K16211 - - 2.851e-210 664.0
HFD1_k127_4675211_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 426.0
HFD1_k127_4675211_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 388.0
HFD1_k127_4675211_12 Forkhead associated domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 341.0
HFD1_k127_4675211_13 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 313.0
HFD1_k127_4675211_14 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 298.0
HFD1_k127_4675211_15 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 319.0
HFD1_k127_4675211_16 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000178 271.0
HFD1_k127_4675211_17 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000001498 223.0
HFD1_k127_4675211_18 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000001269 222.0
HFD1_k127_4675211_19 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000264 221.0
HFD1_k127_4675211_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 5.811e-205 660.0
HFD1_k127_4675211_20 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000001292 180.0
HFD1_k127_4675211_21 - - - - 0.0000000000000000000000000000000000000000000002072 176.0
HFD1_k127_4675211_22 TPR repeat - - - 0.00000000000000000000000000000000000000000001843 182.0
HFD1_k127_4675211_23 Protein of unknown function (DUF3465) - - - 0.0000000000000000000000000000000000000000008163 165.0
HFD1_k127_4675211_24 YCII-related domain - - - 0.00000000000000000000000000000000000002712 146.0
HFD1_k127_4675211_25 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000004514 144.0
HFD1_k127_4675211_26 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000001947 140.0
HFD1_k127_4675211_27 - - - - 0.000000000000000000000000000001699 124.0
HFD1_k127_4675211_28 Methyltransferase domain - - - 0.00000000000000000000000000357 121.0
HFD1_k127_4675211_29 Histidine kinase - - - 0.0000000000000000000000001039 110.0
HFD1_k127_4675211_3 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 4.91e-204 653.0
HFD1_k127_4675211_30 catechol 1,2-dioxygenase - - - 0.0000000000000009592 87.0
HFD1_k127_4675211_32 DinB family - - - 0.000000000001611 74.0
HFD1_k127_4675211_33 Bacterial regulatory protein, Fis family K02481,K02667 - - 0.000000000001748 75.0
HFD1_k127_4675211_34 Domain of unknown function (DUF4956) - - - 0.0000000003739 70.0
HFD1_k127_4675211_35 - - - - 0.000000008761 68.0
HFD1_k127_4675211_36 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00001321 56.0
HFD1_k127_4675211_37 - - - - 0.000215 44.0
HFD1_k127_4675211_38 nuclease - - - 0.0006958 50.0
HFD1_k127_4675211_4 Domain of unknown function (DUF5110) K01187 - 3.2.1.20 7.13e-201 652.0
HFD1_k127_4675211_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 2.824e-195 640.0
HFD1_k127_4675211_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 578.0
HFD1_k127_4675211_7 Glucodextranase, domain N K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 576.0
HFD1_k127_4675211_8 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 572.0
HFD1_k127_4675211_9 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 525.0
HFD1_k127_4678741_0 cellulose binding - - - 0.0 1562.0
HFD1_k127_4678741_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000001169 218.0
HFD1_k127_4678741_2 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000001574 188.0
HFD1_k127_4678741_3 PhoQ Sensor K07640 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001997 187.0
HFD1_k127_4678741_4 - - - - 0.00000000000000000000000000000000000000000003487 168.0
HFD1_k127_4678741_5 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000703 136.0
HFD1_k127_4678741_6 - - - - 0.00002792 49.0
HFD1_k127_4777332_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 434.0
HFD1_k127_4777332_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 414.0
HFD1_k127_4777332_2 Serine aminopeptidase, S33 - - - 0.0000003883 62.0
HFD1_k127_4817735_0 Alpha-2-Macroglobulin K06894 - - 5.809e-305 992.0
HFD1_k127_4817735_1 PFAM Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 462.0
HFD1_k127_4817735_10 - - - - 0.0006042 51.0
HFD1_k127_4817735_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 340.0
HFD1_k127_4817735_3 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000006171 229.0
HFD1_k127_4817735_4 Protein of unknown function (DUF1175) K09934 - - 0.000000000000000000000000000000000000000000000000001011 193.0
HFD1_k127_4817735_5 Penicillin binding protein transpeptidase domain - - - 0.00000000000000000000000002061 127.0
HFD1_k127_4817735_6 extracellular polysaccharide biosynthetic process K13582 - - 0.00000000000000000000009266 110.0
HFD1_k127_4817735_7 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000005722 96.0
HFD1_k127_4817735_8 - K05826 - - 0.0000000003672 62.0
HFD1_k127_4817735_9 domain protein K14475 - - 0.0000001248 61.0
HFD1_k127_4830914_0 Radical SAM - - - 1e-323 1003.0
HFD1_k127_4830914_1 PFAM type II secretion system protein E K02283,K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 564.0
HFD1_k127_4830914_10 type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000001112 200.0
HFD1_k127_4830914_11 NUBPL iron-transfer P-loop NTPase K02282 - - 0.00000000000000000000000000000000000000000000000000007108 203.0
HFD1_k127_4830914_12 protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000000000005941 160.0
HFD1_k127_4830914_13 PFAM Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000001091 145.0
HFD1_k127_4830914_14 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000001162 119.0
HFD1_k127_4830914_15 Tetratricopeptide repeat - - - 0.0000000000000003762 89.0
HFD1_k127_4830914_16 TadE-like protein - - - 0.000000000000001386 84.0
HFD1_k127_4830914_17 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000002603 78.0
HFD1_k127_4830914_18 - - - - 0.0000003811 61.0
HFD1_k127_4830914_19 TadE-like protein - - - 0.00002984 52.0
HFD1_k127_4830914_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 355.0
HFD1_k127_4830914_20 - - - - 0.0009532 50.0
HFD1_k127_4830914_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 309.0
HFD1_k127_4830914_4 SNARE associated Golgi protein K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 292.0
HFD1_k127_4830914_5 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004691 291.0
HFD1_k127_4830914_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000384 246.0
HFD1_k127_4830914_7 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000004673 239.0
HFD1_k127_4830914_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000001203 228.0
HFD1_k127_4830914_9 Type II secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000008035 222.0
HFD1_k127_4837218_0 Carboxypeptidase regulatory-like domain - - - 8.262e-214 704.0
HFD1_k127_4837218_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 381.0
HFD1_k127_4837218_2 M1 (1,4-beta-N-acetylmuramidase) K07273 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 300.0
HFD1_k127_4837218_3 Enoyl-CoA hydratase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000159 279.0
HFD1_k127_4837218_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
HFD1_k127_4837218_5 transcriptional - - - 0.00000000000000000009725 94.0
HFD1_k127_4837218_6 Tetratricopeptide repeat - - - 0.0003875 52.0
HFD1_k127_4851158_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.714e-302 947.0
HFD1_k127_4851158_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.649e-213 685.0
HFD1_k127_4851158_10 Putative zinc-finger - - - 0.0001534 52.0
HFD1_k127_4851158_2 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000038 274.0
HFD1_k127_4851158_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000003523 223.0
HFD1_k127_4851158_4 - - - - 0.00000000000000000000000000000000000000000000000000001453 201.0
HFD1_k127_4851158_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000002494 176.0
HFD1_k127_4851158_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000007252 89.0
HFD1_k127_4851158_7 CS domain K13993 - - 0.000000000002635 73.0
HFD1_k127_4851158_8 Domain of unknown function (DUF4956) - - - 0.000000004329 68.0
HFD1_k127_4851158_9 Tyrosine phosphatase family - - - 0.00001411 55.0
HFD1_k127_4857851_0 Glycogen debranching enzyme - - - 6.68e-240 757.0
HFD1_k127_4857851_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 561.0
HFD1_k127_4857851_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 405.0
HFD1_k127_4857851_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000007562 221.0
HFD1_k127_4857851_4 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000418 217.0
HFD1_k127_4857851_5 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000004295 185.0
HFD1_k127_4857851_6 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000002321 145.0
HFD1_k127_4857851_7 DoxX-like family - - - 0.0000000000000000000000000000000003381 136.0
HFD1_k127_4857851_8 DinB family - - - 0.000000000000000000000004675 109.0
HFD1_k127_4857851_9 lipopolysaccharide transport K22110 - - 0.000000000000001113 76.0
HFD1_k127_4946008_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 5.226e-292 915.0
HFD1_k127_4946008_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 550.0
HFD1_k127_4946008_10 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000001044 251.0
HFD1_k127_4946008_11 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009247 254.0
HFD1_k127_4946008_12 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000625 248.0
HFD1_k127_4946008_13 methyltransferase K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000000000000000000003669 233.0
HFD1_k127_4946008_14 ABC-2 type transporter K01992,K09690,K09691,K09692 - - 0.0000000000000000000000000000000000000000000000000000000000064 216.0
HFD1_k127_4946008_15 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000007173 180.0
HFD1_k127_4946008_16 - - - - 0.000000000000000000000000000000000000003393 168.0
HFD1_k127_4946008_17 protein import - - - 0.0000000000000004813 93.0
HFD1_k127_4946008_18 exo-alpha-(2->6)-sialidase activity K01406 - 3.4.24.40 0.00002476 56.0
HFD1_k127_4946008_19 COG2931 RTX toxins and related Ca2 -binding - - - 0.000213 55.0
HFD1_k127_4946008_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 500.0
HFD1_k127_4946008_20 pyrroloquinoline quinone binding - - - 0.0008466 53.0
HFD1_k127_4946008_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 486.0
HFD1_k127_4946008_4 RmlD substrate binding domain K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 428.0
HFD1_k127_4946008_5 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 405.0
HFD1_k127_4946008_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 377.0
HFD1_k127_4946008_7 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 303.0
HFD1_k127_4946008_8 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005363 287.0
HFD1_k127_4946008_9 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 261.0
HFD1_k127_4948269_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.978e-208 661.0
HFD1_k127_4948269_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 477.0
HFD1_k127_4948269_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 467.0
HFD1_k127_4948269_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 404.0
HFD1_k127_4948269_4 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 355.0
HFD1_k127_4948269_5 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 325.0
HFD1_k127_4948269_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000009001 231.0
HFD1_k127_4948269_7 - - - - 0.0000000000000000000000000000001133 141.0
HFD1_k127_4948269_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000000005678 105.0
HFD1_k127_4948894_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1079.0
HFD1_k127_4948894_1 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 464.0
HFD1_k127_4948894_10 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000002672 146.0
HFD1_k127_4948894_11 unfolded protein binding K06142 GO:0001530,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019867,GO:0022417,GO:0022607,GO:0030288,GO:0030312,GO:0030313,GO:0031647,GO:0031975,GO:0032978,GO:0033036,GO:0034613,GO:0042597,GO:0042802,GO:0043163,GO:0043165,GO:0043170,GO:0044085,GO:0044091,GO:0044238,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0050821,GO:0051082,GO:0051179,GO:0051205,GO:0051234,GO:0051604,GO:0051641,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097367,GO:1901564 - 0.000001569 58.0
HFD1_k127_4948894_12 Outer membrane protein (OmpH-like) K06142 - - 0.00003463 54.0
HFD1_k127_4948894_13 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides - - - 0.0002085 54.0
HFD1_k127_4948894_2 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 352.0
HFD1_k127_4948894_3 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 304.0
HFD1_k127_4948894_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 297.0
HFD1_k127_4948894_5 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000451 236.0
HFD1_k127_4948894_6 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.000000000000000000000000000000000000000000000000000000000000000005208 240.0
HFD1_k127_4948894_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000985 192.0
HFD1_k127_4948894_8 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000003603 177.0
HFD1_k127_4948894_9 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000843 152.0
HFD1_k127_4951565_0 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000008125 203.0
HFD1_k127_4951565_1 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000000007087 166.0
HFD1_k127_4951565_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.0000000000000000000001473 102.0
HFD1_k127_4951565_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000251 80.0
HFD1_k127_4951565_4 Thioesterase superfamily - - - 0.000000000000002927 80.0
HFD1_k127_4953098_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 439.0
HFD1_k127_4953098_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 327.0
HFD1_k127_4953098_2 Chlorophyllase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 291.0
HFD1_k127_4953098_3 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000003146 187.0
HFD1_k127_4953098_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000001354 156.0
HFD1_k127_4953098_6 23S rRNA-intervening sequence protein - - - 0.000000002217 63.0
HFD1_k127_4971330_0 GMC oxidoreductase - - - 1.7e-287 893.0
HFD1_k127_4971330_1 catalase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 582.0
HFD1_k127_4971330_10 Protein of unknown function with PCYCGC motif - - - 0.00000000000000000006483 96.0
HFD1_k127_4971330_12 YtkA-like - - - 0.0000000000000003155 85.0
HFD1_k127_4971330_14 Peptidase M16 inactive domain - - - 0.000000000169 72.0
HFD1_k127_4971330_15 peroxidase - - - 0.000003062 52.0
HFD1_k127_4971330_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 535.0
HFD1_k127_4971330_3 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 495.0
HFD1_k127_4971330_4 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 395.0
HFD1_k127_4971330_5 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002441 282.0
HFD1_k127_4971330_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007424 227.0
HFD1_k127_4971330_7 - - - - 0.000000000000000000000000000000000000000000000000000000000001917 211.0
HFD1_k127_4971330_8 Protein of unknown function (DUF3179) - - - 0.000000000000000000000000000000000000000000000000000000001314 208.0
HFD1_k127_4971330_9 - - - - 0.000000000000000000000000000000000000000003372 157.0
HFD1_k127_4990152_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 428.0
HFD1_k127_4990152_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 418.0
HFD1_k127_4990152_2 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 364.0
HFD1_k127_4990152_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.000000000000000000000000000000000000000000000000000000000000001488 221.0
HFD1_k127_4990152_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000291 213.0
HFD1_k127_4990152_5 Domain of unknown function (DUF5011) - - - 0.00000000000000000000000000000000000000000000000001043 205.0
HFD1_k127_4990152_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000002207 181.0
HFD1_k127_5017649_0 in Yersinia the HmsR protein is an inner membrane protein K11936 - - 0.0 1149.0
HFD1_k127_5017649_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.86e-217 691.0
HFD1_k127_5017649_10 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 336.0
HFD1_k127_5017649_11 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 298.0
HFD1_k127_5017649_12 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001763 282.0
HFD1_k127_5017649_13 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005895 290.0
HFD1_k127_5017649_14 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000005887 268.0
HFD1_k127_5017649_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000004191 228.0
HFD1_k127_5017649_16 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000005106 191.0
HFD1_k127_5017649_17 PFAM metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000001984 181.0
HFD1_k127_5017649_18 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000001952 139.0
HFD1_k127_5017649_19 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000004938 97.0
HFD1_k127_5017649_2 Amino acid permease K03294 - - 5.444e-206 653.0
HFD1_k127_5017649_20 Protein of unknown function (DUF664) - - - 0.0000000005164 68.0
HFD1_k127_5017649_21 Domain of unknown function (DUF4440) - - - 0.000005409 56.0
HFD1_k127_5017649_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 593.0
HFD1_k127_5017649_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 532.0
HFD1_k127_5017649_5 DNA polymerase K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 471.0
HFD1_k127_5017649_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 445.0
HFD1_k127_5017649_7 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 433.0
HFD1_k127_5017649_8 Sodium:dicarboxylate symporter family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 398.0
HFD1_k127_5017649_9 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 376.0
HFD1_k127_5019194_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 588.0
HFD1_k127_5019194_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 532.0
HFD1_k127_5019194_10 Vitamin k epoxide reductase K00368 - 1.7.2.1 0.000009414 53.0
HFD1_k127_5019194_11 Carboxypeptidase regulatory-like domain - - - 0.00001088 57.0
HFD1_k127_5019194_12 Protein of unknown function (DUF4019) - - - 0.0004918 50.0
HFD1_k127_5019194_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 381.0
HFD1_k127_5019194_3 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 359.0
HFD1_k127_5019194_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 326.0
HFD1_k127_5019194_5 Oxidoreductase, molybdopterin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 287.0
HFD1_k127_5019194_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001247 227.0
HFD1_k127_5019194_7 DSBA-like thioredoxin domain K21990 - - 0.0000000000000000000000000000000000002979 151.0
HFD1_k127_5019194_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000001276 100.0
HFD1_k127_5019194_9 Domain of unknown function (DUF4870) - - - 0.000000000000000000001185 100.0
HFD1_k127_5034787_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0 1066.0
HFD1_k127_5034787_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 567.0
HFD1_k127_5034787_2 PFAM Aldo keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 432.0
HFD1_k127_5034787_3 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000005785 233.0
HFD1_k127_5034787_4 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000003489 223.0
HFD1_k127_5034787_5 PHP domain protein - - - 0.000000000000000000000000000000000005741 151.0
HFD1_k127_5042529_0 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 573.0
HFD1_k127_5042529_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 537.0
HFD1_k127_5042529_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 453.0
HFD1_k127_5042529_3 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000001072 239.0
HFD1_k127_5042529_4 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000002466 214.0
HFD1_k127_5042529_5 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000004424 177.0
HFD1_k127_5042529_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000009819 52.0
HFD1_k127_5042529_7 ArsR family transcriptional regulator - - - 0.000001991 59.0
HFD1_k127_5094631_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 569.0
HFD1_k127_5094631_1 NeuB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 398.0
HFD1_k127_5094631_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 311.0
HFD1_k127_5094631_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002182 252.0
HFD1_k127_5094631_4 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000005305 100.0
HFD1_k127_5094631_5 Cytidylyltransferase K00983 - 2.7.7.43 0.000000000000000003646 86.0
HFD1_k127_5094631_6 WbqC-like protein family - - - 0.0000543 48.0
HFD1_k127_5123274_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 471.0
HFD1_k127_5123274_1 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 454.0
HFD1_k127_5123274_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 363.0
HFD1_k127_5123274_3 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 278.0
HFD1_k127_5123274_4 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000136 239.0
HFD1_k127_5123274_5 - - - - 0.00000000000000000000000000000000000000004149 167.0
HFD1_k127_5123274_6 acylphosphatase activity K01512 - 3.6.1.7 0.000000000000004185 79.0
HFD1_k127_5123274_7 Pilus assembly protein PilX K02673 - - 0.0000000000002156 83.0
HFD1_k127_5123274_8 pilus assembly protein PilW K02672 - - 0.0001255 52.0
HFD1_k127_5127752_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 528.0
HFD1_k127_5127752_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 498.0
HFD1_k127_5127752_10 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000003604 193.0
HFD1_k127_5127752_11 Cell division protein FtsQ K03589 - - 0.00003067 55.0
HFD1_k127_5127752_12 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0009642 46.0
HFD1_k127_5127752_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 408.0
HFD1_k127_5127752_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 403.0
HFD1_k127_5127752_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 394.0
HFD1_k127_5127752_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 357.0
HFD1_k127_5127752_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 323.0
HFD1_k127_5127752_7 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 323.0
HFD1_k127_5127752_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 307.0
HFD1_k127_5127752_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 299.0
HFD1_k127_5132695_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 291.0
HFD1_k127_5132695_1 - - - - 0.000000000000000000000000000000000000000000000000000008541 198.0
HFD1_k127_5132695_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000003698 166.0
HFD1_k127_5132695_3 cheY-homologous receiver domain - - - 0.000000000000000000000000005856 114.0
HFD1_k127_5132695_4 Methylase involved in ubiquinone menaquinone biosynthesis K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.0000000000004513 79.0
HFD1_k127_5132695_5 Psort location CytoplasmicMembrane, score - - - 0.0000001578 61.0
HFD1_k127_5162241_0 PFAM Prolyl oligopeptidase family - - - 2.964e-283 882.0
HFD1_k127_5162241_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 327.0
HFD1_k127_5162241_2 - - - - 0.00000000000000000000000000000000000000000000000001084 186.0
HFD1_k127_5162241_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000575 111.0
HFD1_k127_5165333_0 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 436.0
HFD1_k127_5165333_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 406.0
HFD1_k127_5165333_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000001277 211.0
HFD1_k127_5165333_3 Yip1 domain - - - 0.0000000000000000001827 98.0
HFD1_k127_5165333_4 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000001551 68.0
HFD1_k127_5186588_0 Putative carbohydrate binding domain K12373 - 3.2.1.52 2.376e-232 734.0
HFD1_k127_5186588_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 383.0
HFD1_k127_5186588_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000003152 99.0
HFD1_k127_5191690_0 Belongs to the DegT DnrJ EryC1 family K20429 - 2.6.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 558.0
HFD1_k127_5191690_1 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 421.0
HFD1_k127_5191690_10 - - - - 0.000000000000000004276 93.0
HFD1_k127_5191690_2 ATPases associated with a variety of cellular activities K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 382.0
HFD1_k127_5191690_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 350.0
HFD1_k127_5191690_4 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 304.0
HFD1_k127_5191690_6 Cytidylyltransferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000000008683 239.0
HFD1_k127_5191690_7 Methyltransferase type 11 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000001635 165.0
HFD1_k127_5191690_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000007138 152.0
HFD1_k127_5191690_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000005348 101.0
HFD1_k127_5243638_0 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000004653 267.0
HFD1_k127_5243638_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000001392 154.0
HFD1_k127_5243638_2 dioxygenase activity - - - 0.0000000000000000000000000003075 124.0
HFD1_k127_5243638_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000009975 121.0
HFD1_k127_5243638_4 - - - - 0.0000000000266 69.0
HFD1_k127_5243638_5 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000002622 68.0
HFD1_k127_5243638_6 - - - - 0.0001077 50.0
HFD1_k127_5243638_7 Methyltransferase domain - - - 0.0002154 52.0
HFD1_k127_5243638_8 Glycosyltransferase family 92 - - - 0.0002347 52.0
HFD1_k127_5274317_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 442.0
HFD1_k127_5274317_1 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 421.0
HFD1_k127_5274317_2 ATPases associated with a variety of cellular activities K10823,K10824 - 3.6.3.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 376.0
HFD1_k127_5274317_3 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 392.0
HFD1_k127_5274317_4 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
HFD1_k127_5274317_5 PFAM Binding-protein-dependent transport system inner membrane component K02033,K15581,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 339.0
HFD1_k127_5274317_6 Methyltransferase domain K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000001948 224.0
HFD1_k127_5277596_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 394.0
HFD1_k127_5277596_1 - - - - 0.000000000000000000000000000000000000000000000000000000108 201.0
HFD1_k127_5277596_2 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000007716 189.0
HFD1_k127_5277596_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000001015 100.0
HFD1_k127_5357599_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 404.0
HFD1_k127_5357599_1 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 344.0
HFD1_k127_5357599_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001577 258.0
HFD1_k127_5357599_3 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000001075 214.0
HFD1_k127_5357599_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000006226 156.0
HFD1_k127_5357599_5 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000001051 134.0
HFD1_k127_5357599_6 Associated with various cellular activities - - - 0.00000000000000000001152 93.0
HFD1_k127_5368671_0 ThiC-associated domain K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.524e-305 948.0
HFD1_k127_5368671_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein K01322,K01354 - 3.4.21.26,3.4.21.83 3.073e-261 822.0
HFD1_k127_5368671_10 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000001158 163.0
HFD1_k127_5368671_11 phosphoprotein phosphatase activity K07313 - 3.1.3.16 0.000000000000000000000000000000000004197 147.0
HFD1_k127_5368671_12 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000002929 129.0
HFD1_k127_5368671_13 ThiS family K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000001505 120.0
HFD1_k127_5368671_14 - - - - 0.00000000000000000000000000001729 130.0
HFD1_k127_5368671_15 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000000006444 108.0
HFD1_k127_5368671_16 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000005245 71.0
HFD1_k127_5368671_19 Domain of unknown function (DUF309) - - - 0.00000007353 62.0
HFD1_k127_5368671_2 PFAM peptidase - - - 6.916e-195 623.0
HFD1_k127_5368671_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 512.0
HFD1_k127_5368671_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 443.0
HFD1_k127_5368671_5 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 361.0
HFD1_k127_5368671_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 321.0
HFD1_k127_5368671_7 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 321.0
HFD1_k127_5368671_8 oxidoreductase activity K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002994 282.0
HFD1_k127_5368671_9 Thioredoxin reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000705 183.0
HFD1_k127_5372612_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 323.0
HFD1_k127_5372612_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000003837 118.0
HFD1_k127_541621_0 Sigma-70 region 2 K03088 - - 1.587e-225 704.0
HFD1_k127_541621_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 578.0
HFD1_k127_541621_2 YCII-related domain - - - 0.00000000000000000000000000000000000385 138.0
HFD1_k127_5443372_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.957e-218 689.0
HFD1_k127_5443372_1 Dehydrogenase K02030,K03810 - - 1.399e-208 670.0
HFD1_k127_5443372_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 489.0
HFD1_k127_5443372_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 424.0
HFD1_k127_5443372_4 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.00000000000000000000000000000000000000000000000000000000000000000004135 246.0
HFD1_k127_5443372_5 methyltransferase K05928 - 2.1.1.95 0.000000000000000000000000000000000000000000000000000000000647 211.0
HFD1_k127_5443372_6 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000001596 176.0
HFD1_k127_5443372_7 cheY-homologous receiver domain - - - 0.0000000000000000003965 94.0
HFD1_k127_5443372_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001284 70.0
HFD1_k127_5443372_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000004153 66.0
HFD1_k127_5455162_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 383.0
HFD1_k127_5455162_1 UDP-N-acetylglucosamine 2-epimerase K08068,K18429 - 3.2.1.183,3.2.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 379.0
HFD1_k127_5455162_2 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784,K21211 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005492 268.0
HFD1_k127_5455162_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000006715 226.0
HFD1_k127_5455162_4 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000009199 205.0
HFD1_k127_5455162_5 TIGRFAM Sialic acid O-acyltransferase, NeuD - - - 0.000000000000000000000000000000000000000000000000001559 189.0
HFD1_k127_5455162_6 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000004808 165.0
HFD1_k127_5474821_0 metalloendopeptidase activity K01283 - 3.4.15.1 7.562e-257 804.0
HFD1_k127_5474821_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 606.0
HFD1_k127_5474821_10 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.000000000000000000000000000000000000000000000000000000000000000004577 234.0
HFD1_k127_5474821_11 oxidoreductase activity K12511 - - 0.00000000000000000000000000000000000003398 156.0
HFD1_k127_5474821_12 metal cluster binding - - - 0.000000000000000000000000000000000002292 145.0
HFD1_k127_5474821_13 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000002584 112.0
HFD1_k127_5474821_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000008499 87.0
HFD1_k127_5474821_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 418.0
HFD1_k127_5474821_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 360.0
HFD1_k127_5474821_4 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 360.0
HFD1_k127_5474821_5 family UPF0027 K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 314.0
HFD1_k127_5474821_6 DEAD/H associated K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 318.0
HFD1_k127_5474821_7 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001865 276.0
HFD1_k127_5474821_8 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000001528 261.0
HFD1_k127_5474821_9 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001937 249.0
HFD1_k127_5485988_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1197.0
HFD1_k127_5485988_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000878 270.0
HFD1_k127_5485988_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000005969 166.0
HFD1_k127_549034_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000002896 231.0
HFD1_k127_549034_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000001036 177.0
HFD1_k127_549034_2 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000001046 148.0
HFD1_k127_549034_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000946 132.0
HFD1_k127_549034_4 Periplasmic or secreted lipoprotein - - - 0.0000000000001163 79.0
HFD1_k127_549034_5 - - - - 0.0000000007959 72.0
HFD1_k127_549034_6 GUN4-like - - - 0.00000002879 63.0
HFD1_k127_5508300_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 600.0
HFD1_k127_5508300_1 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 423.0
HFD1_k127_5508300_2 Carboxypeptidase regulatory-like domain - - - 0.0000008791 57.0
HFD1_k127_5552505_0 HEAT repeats - - - 0.00000000000000000000000000001617 133.0
HFD1_k127_5552505_1 deoxyhypusine monooxygenase activity K05385 - - 0.0000003197 60.0
HFD1_k127_5557067_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 471.0
HFD1_k127_5557067_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 340.0
HFD1_k127_5557067_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 307.0
HFD1_k127_5557067_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000006331 136.0
HFD1_k127_5557067_4 - - - - 0.0000000003334 70.0
HFD1_k127_5558039_0 helicase activity - - - 0.0 1022.0
HFD1_k127_5558039_1 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 475.0
HFD1_k127_5558039_2 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 403.0
HFD1_k127_5558039_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009382 256.0
HFD1_k127_5558039_4 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000126 224.0
HFD1_k127_5558039_5 cAMP biosynthetic process - - - 0.00000000000000000000003943 115.0
HFD1_k127_55661_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 3.382e-246 774.0
HFD1_k127_55661_1 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 605.0
HFD1_k127_55661_10 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 351.0
HFD1_k127_55661_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 351.0
HFD1_k127_55661_12 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 344.0
HFD1_k127_55661_13 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 337.0
HFD1_k127_55661_14 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 311.0
HFD1_k127_55661_15 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
HFD1_k127_55661_16 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000328 273.0
HFD1_k127_55661_17 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000002405 215.0
HFD1_k127_55661_18 Lamin Tail Domain K07004 - - 0.000000000000000000000000000000000000000000000000001476 208.0
HFD1_k127_55661_19 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000001585 160.0
HFD1_k127_55661_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 538.0
HFD1_k127_55661_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000001686 151.0
HFD1_k127_55661_21 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000001887 159.0
HFD1_k127_55661_22 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000002256 121.0
HFD1_k127_55661_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000141 110.0
HFD1_k127_55661_24 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000005177 116.0
HFD1_k127_55661_25 Ribosomal L32p protein family K02911 - - 0.000000000000000000005291 94.0
HFD1_k127_55661_26 - - - - 0.00000000000004578 83.0
HFD1_k127_55661_27 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000007383 74.0
HFD1_k127_55661_28 peptidyl-tyrosine sulfation - - - 0.000000003395 68.0
HFD1_k127_55661_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000006727 48.0
HFD1_k127_55661_3 RQC K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 527.0
HFD1_k127_55661_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 501.0
HFD1_k127_55661_5 amino acid peptide transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 449.0
HFD1_k127_55661_6 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 410.0
HFD1_k127_55661_7 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 393.0
HFD1_k127_55661_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 366.0
HFD1_k127_55661_9 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 353.0
HFD1_k127_557126_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.163e-255 807.0
HFD1_k127_557126_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000001662 211.0
HFD1_k127_557126_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000005312 127.0
HFD1_k127_55884_0 Associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 316.0
HFD1_k127_55884_1 COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000005846 233.0
HFD1_k127_55884_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000001299 160.0
HFD1_k127_5635390_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 581.0
HFD1_k127_5635390_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000006909 186.0
HFD1_k127_5642097_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 429.0
HFD1_k127_5642097_1 PFAM Metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 287.0
HFD1_k127_5642097_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000006276 178.0
HFD1_k127_5642097_3 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000004754 147.0
HFD1_k127_5642097_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000005418 56.0
HFD1_k127_5659729_0 PFAM Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 616.0
HFD1_k127_5659729_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 539.0
HFD1_k127_5659729_10 - - - - 0.0000000000000000000000000000000000000000000000001912 190.0
HFD1_k127_5659729_11 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000005782 181.0
HFD1_k127_5659729_12 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000004053 158.0
HFD1_k127_5659729_13 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000001202 160.0
HFD1_k127_5659729_14 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000008112 149.0
HFD1_k127_5659729_15 nucleotide catabolic process K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000001572 104.0
HFD1_k127_5659729_16 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000000000000989 92.0
HFD1_k127_5659729_2 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 433.0
HFD1_k127_5659729_3 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 368.0
HFD1_k127_5659729_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 316.0
HFD1_k127_5659729_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 330.0
HFD1_k127_5659729_6 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 293.0
HFD1_k127_5659729_7 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007182 276.0
HFD1_k127_5659729_8 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000002228 221.0
HFD1_k127_5659729_9 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000001978 199.0
HFD1_k127_5678834_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 572.0
HFD1_k127_5678834_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 446.0
HFD1_k127_5678834_2 - - - - 0.0000000001528 64.0
HFD1_k127_5678834_3 Belongs to the UPF0102 family K07460 - - 0.000000001364 62.0
HFD1_k127_5679597_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000002711 275.0
HFD1_k127_5679597_1 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000003233 201.0
HFD1_k127_5679597_2 PFAM transferase hexapeptide repeat containing protein - - - 0.0000000000000000000000000000000000000009032 153.0
HFD1_k127_5682051_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.128e-258 818.0
HFD1_k127_5682051_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 314.0
HFD1_k127_5682051_2 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000001189 138.0
HFD1_k127_5682051_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0001561 44.0
HFD1_k127_569058_0 Carboxypeptidase regulatory-like domain - - - 5.851e-224 739.0
HFD1_k127_569058_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 619.0
HFD1_k127_569058_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 567.0
HFD1_k127_569058_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 506.0
HFD1_k127_569058_4 4Fe-4S binding domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 344.0
HFD1_k127_569058_5 Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000004444 259.0
HFD1_k127_569058_6 tail collar domain protein - - - 0.00000000000000000000000000000000000000001034 164.0
HFD1_k127_569058_7 Glycosyl hydrolase-like 10 - - - 0.000000000000000005439 92.0
HFD1_k127_569058_8 - - - - 0.0000000006492 69.0
HFD1_k127_5709935_0 efflux transmembrane transporter activity - - - 2.671e-253 805.0
HFD1_k127_5709935_1 MacB-like periplasmic core domain - - - 3.168e-238 760.0
HFD1_k127_5709935_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 431.0
HFD1_k127_5709935_11 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 386.0
HFD1_k127_5709935_12 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 350.0
HFD1_k127_5709935_13 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 325.0
HFD1_k127_5709935_14 FtsX-like permease family - - - 0.00000000000000000000955 96.0
HFD1_k127_5709935_2 efflux transmembrane transporter activity K02004 - - 3.214e-226 726.0
HFD1_k127_5709935_3 FtsX-like permease family - - - 4.444e-213 692.0
HFD1_k127_5709935_4 MacB-like periplasmic core domain - - - 1.089e-208 676.0
HFD1_k127_5709935_5 efflux transmembrane transporter activity K02004 - - 6.675e-205 665.0
HFD1_k127_5709935_6 efflux transmembrane transporter activity - - - 4.877e-201 653.0
HFD1_k127_5709935_7 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 595.0
HFD1_k127_5709935_8 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 593.0
HFD1_k127_5709935_9 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 580.0
HFD1_k127_5747648_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 449.0
HFD1_k127_5747648_1 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 349.0
HFD1_k127_5747648_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003198 278.0
HFD1_k127_5797224_0 Tricorn protease C1 domain K08676 - - 0.0 1263.0
HFD1_k127_5797224_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.246e-230 730.0
HFD1_k127_5797224_10 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000003955 207.0
HFD1_k127_5797224_11 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000003095 179.0
HFD1_k127_5797224_12 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000005676 98.0
HFD1_k127_5797224_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 583.0
HFD1_k127_5797224_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 552.0
HFD1_k127_5797224_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 406.0
HFD1_k127_5797224_5 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 356.0
HFD1_k127_5797224_6 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 342.0
HFD1_k127_5797224_7 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002938 267.0
HFD1_k127_5797224_8 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000003478 241.0
HFD1_k127_5797224_9 aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000008291 219.0
HFD1_k127_5854298_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.293e-211 666.0
HFD1_k127_5854298_1 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 625.0
HFD1_k127_5854298_10 Phage integrase, N-terminal SAM-like domain K14059 - - 0.0000000000000000000000000000000000000000000000007754 187.0
HFD1_k127_5854298_11 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000004534 167.0
HFD1_k127_5854298_12 BMC - - - 0.0000000000000000000000000000000000002872 146.0
HFD1_k127_5854298_13 - - - - 0.000000000000000000000000000000000001439 141.0
HFD1_k127_5854298_14 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000005618 108.0
HFD1_k127_5854298_15 WD40 domain protein beta Propeller - - - 0.000000000000001072 92.0
HFD1_k127_5854298_16 Helix-turn-helix domain K15539 - - 0.0000000000001259 78.0
HFD1_k127_5854298_2 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 524.0
HFD1_k127_5854298_3 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 404.0
HFD1_k127_5854298_4 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 324.0
HFD1_k127_5854298_5 Peptidase M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 331.0
HFD1_k127_5854298_6 Related to alanyl-tRNA synthetase HxxxH domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 295.0
HFD1_k127_5854298_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002263 227.0
HFD1_k127_5854298_8 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000007061 201.0
HFD1_k127_5854298_9 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000000003157 195.0
HFD1_k127_5878093_0 ABC transporter transmembrane region K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 554.0
HFD1_k127_5878093_1 lytic transglycosylase activity K03194 - - 0.00000001715 64.0
HFD1_k127_5878093_2 (ABC) transporter K06147,K18889 - - 0.000000835 50.0
HFD1_k127_5899240_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 472.0
HFD1_k127_5899240_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002812 279.0
HFD1_k127_5899240_2 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000007684 253.0
HFD1_k127_5899240_3 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000004165 152.0
HFD1_k127_5899240_4 iron ion homeostasis - - - 0.00000000000000000000038 109.0
HFD1_k127_5899240_5 von Willebrand factor, type A - - - 0.000000000000000006025 96.0
HFD1_k127_5899240_6 PFAM regulatory protein GntR HTH K07979 - - 0.00000000000000001685 87.0
HFD1_k127_5899240_7 C-3'',4'' desaturase CrtD - - - 0.000000000000006769 87.0
HFD1_k127_5899240_8 oxidoreductase activity K12511 - - 0.0000000007008 72.0
HFD1_k127_5899240_9 PFAM Abortive infection protein K07052 - - 0.0001936 52.0
HFD1_k127_5920928_0 Peptidase M14, carboxypeptidase A - - - 2.602e-231 729.0
HFD1_k127_5920928_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 662.0
HFD1_k127_5920928_2 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 527.0
HFD1_k127_5920928_3 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 420.0
HFD1_k127_5920928_4 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 391.0
HFD1_k127_5920928_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 387.0
HFD1_k127_5920928_6 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000005851 236.0
HFD1_k127_5920928_7 glycosyl transferase, family 39 - - - 0.0001613 54.0
HFD1_k127_593703_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 525.0
HFD1_k127_593703_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 374.0
HFD1_k127_593703_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 330.0
HFD1_k127_593703_3 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 308.0
HFD1_k127_593703_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000002655 181.0
HFD1_k127_593703_5 methyltransferase - - - 0.00000000000000000000000000008428 124.0
HFD1_k127_593703_6 O-antigen ligase like membrane protein - - - 0.0000003243 63.0
HFD1_k127_596084_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 1.044e-270 848.0
HFD1_k127_596084_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 546.0
HFD1_k127_596084_2 cytochrome c oxidase K02351 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 349.0
HFD1_k127_596084_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 332.0
HFD1_k127_596084_4 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 323.0
HFD1_k127_596084_5 PQQ-dependent catabolism-associated beta-propeller protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001854 237.0
HFD1_k127_596084_6 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000003177 162.0
HFD1_k127_596084_7 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000002207 145.0
HFD1_k127_596084_8 PFAM PRC-barrel domain - - - 0.000000000000000000000000004718 115.0
HFD1_k127_596084_9 - - - - 0.000000000000000000000008458 104.0
HFD1_k127_5988269_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 336.0
HFD1_k127_5988269_1 Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 338.0
HFD1_k127_5988269_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 336.0
HFD1_k127_5988269_3 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001151 299.0
HFD1_k127_5988269_4 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000009787 192.0
HFD1_k127_5988269_5 Zn peptidase K21686 - - 0.0000000000000000000000006964 111.0
HFD1_k127_5988269_7 sequence-specific DNA binding - - - 0.0001151 52.0
HFD1_k127_5988401_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 576.0
HFD1_k127_5988401_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 335.0
HFD1_k127_5988401_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003327 278.0
HFD1_k127_5988401_3 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000004864 234.0
HFD1_k127_5988401_4 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000005297 209.0
HFD1_k127_5988401_5 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000006211 172.0
HFD1_k127_5988401_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K02491,K13533 - 2.7.13.3 0.000000000000000000000000000000000000000002677 181.0
HFD1_k127_5988401_7 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000003271 111.0
HFD1_k127_5988401_8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K10697 - - 0.00000000000000000003705 108.0
HFD1_k127_5997912_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 615.0
HFD1_k127_5997912_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 589.0
HFD1_k127_5997912_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000004883 166.0
HFD1_k127_5997912_11 HAD-superfamily hydrolase subfamily IA, variant 3 K01091,K01838 - 3.1.3.18,5.4.2.6 0.000000000000000000000000000000003634 137.0
HFD1_k127_5997912_12 histone H2A K63-linked ubiquitination - - - 0.0000000000002878 77.0
HFD1_k127_5997912_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000003084 84.0
HFD1_k127_5997912_14 PFAM Tetratricopeptide repeat - - - 0.000000000003897 79.0
HFD1_k127_5997912_15 Domain of unknown function (DUF4190) - - - 0.0000001956 59.0
HFD1_k127_5997912_16 - - - - 0.000001472 59.0
HFD1_k127_5997912_17 Heat shock chaperonin-binding motif. K09553 - - 0.0005338 52.0
HFD1_k127_5997912_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 409.0
HFD1_k127_5997912_3 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 421.0
HFD1_k127_5997912_4 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 346.0
HFD1_k127_5997912_5 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 293.0
HFD1_k127_5997912_6 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000002935 232.0
HFD1_k127_5997912_7 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000002441 219.0
HFD1_k127_5997912_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000005634 208.0
HFD1_k127_5997912_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000008695 190.0
HFD1_k127_6001019_0 Domain of unknown function (DUF5117) - - - 4.4e-323 1011.0
HFD1_k127_6001019_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 5.069e-196 622.0
HFD1_k127_6001019_10 Peptidase family M1 domain - - - 0.000000000000000000000000000000000001595 148.0
HFD1_k127_6001019_11 Ferredoxin - - - 0.0000000000000000000000004708 109.0
HFD1_k127_6001019_12 membrane - - - 0.00004587 57.0
HFD1_k127_6001019_13 Putative zinc-finger - - - 0.0006895 50.0
HFD1_k127_6001019_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 499.0
HFD1_k127_6001019_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 429.0
HFD1_k127_6001019_6 heme binding K21472 - - 0.00000000000000000000000000000000000000000000003786 177.0
HFD1_k127_6001019_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000008497 168.0
HFD1_k127_6001019_8 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000005764 180.0
HFD1_k127_6001019_9 Forkhead associated domain - - - 0.000000000000000000000000000000000000001519 166.0
HFD1_k127_6011159_0 Amidase K01426 - 3.5.1.4 6.526e-202 642.0
HFD1_k127_6011159_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 440.0
HFD1_k127_6011159_10 Biopolymer transport protein K03560 - - 0.00000000000003938 76.0
HFD1_k127_6011159_11 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000001384 72.0
HFD1_k127_6011159_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 433.0
HFD1_k127_6011159_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 408.0
HFD1_k127_6011159_4 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 276.0
HFD1_k127_6011159_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001462 251.0
HFD1_k127_6011159_6 Domain of unknown function (DUF4287) - - - 0.00000000000000000000000000000000000000000000000004799 183.0
HFD1_k127_6011159_7 TIGRFAM TonB K03832 - - 0.00000000000000003298 91.0
HFD1_k127_6011159_8 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000041 83.0
HFD1_k127_6011159_9 Belongs to the UPF0102 family K07460 - - 0.000000000000005063 81.0
HFD1_k127_6015530_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 549.0
HFD1_k127_6015530_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000008769 139.0
HFD1_k127_6066457_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 309.0
HFD1_k127_6066457_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001221 261.0
HFD1_k127_6066457_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000001178 227.0
HFD1_k127_6066996_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001416 282.0
HFD1_k127_6066996_1 AAA domain K02450 - - 0.00000000000000000000000000000000000000000000000001571 186.0
HFD1_k127_6066996_2 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000002271 152.0
HFD1_k127_6066996_3 Chain length determinant protein - - - 0.000000000000000000000000000000001361 147.0
HFD1_k127_6066996_4 eight transmembrane protein EpsH - - - 0.000000000000000000000000000009217 124.0
HFD1_k127_6071767_0 Carboxypeptidase regulatory-like domain - - - 0.0 1485.0
HFD1_k127_6071767_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1158.0
HFD1_k127_6071767_10 metallopeptidase activity - - - 0.000000000000000000000000000000815 132.0
HFD1_k127_6071767_11 Penicillinase repressor - - - 0.000000000000000000000115 103.0
HFD1_k127_6071767_12 TonB dependent receptor K16087 - - 0.00000000000008435 86.0
HFD1_k127_6071767_13 - - - - 0.000000000004366 74.0
HFD1_k127_6071767_14 COG0457 FOG TPR repeat - - - 0.00000000006575 68.0
HFD1_k127_6071767_15 peptidase M48, Ste24p - - - 0.0001692 53.0
HFD1_k127_6071767_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 384.0
HFD1_k127_6071767_3 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 360.0
HFD1_k127_6071767_4 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 294.0
HFD1_k127_6071767_5 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000008381 224.0
HFD1_k127_6071767_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000003149 189.0
HFD1_k127_6071767_7 - - - - 0.000000000000000000000000000000000001477 149.0
HFD1_k127_6071767_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000002381 138.0
HFD1_k127_6071767_9 Yqey-like protein K09117 - - 0.000000000000000000000000000000001098 136.0
HFD1_k127_6074153_0 ASPIC and UnbV - - - 5.096e-211 672.0
HFD1_k127_6074153_1 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002841 278.0
HFD1_k127_6074153_2 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001702 269.0
HFD1_k127_6074153_3 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
HFD1_k127_6074153_4 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000007973 178.0
HFD1_k127_6074153_5 - - - - 0.0000000000000000000000000001 122.0
HFD1_k127_6075300_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 430.0
HFD1_k127_6075300_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000001863 259.0
HFD1_k127_6075300_2 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001052 256.0
HFD1_k127_6075300_3 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000001611 258.0
HFD1_k127_6075300_4 Sulfate ABC transporter substrate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000003041 237.0
HFD1_k127_6075300_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000009709 197.0
HFD1_k127_6075300_6 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000001848 192.0
HFD1_k127_6075300_7 TIGRFAM sulfate ABC transporter, inner membrane subunit CysT K02046 - - 0.000000000000000000000000000000000000000000000000001189 194.0
HFD1_k127_6075300_8 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000002142 181.0
HFD1_k127_6075300_9 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000105 104.0
HFD1_k127_6124634_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.284e-222 719.0
HFD1_k127_6124634_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 338.0
HFD1_k127_6124634_2 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001473 274.0
HFD1_k127_6124634_3 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000001733 187.0
HFD1_k127_6124634_4 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000133 119.0
HFD1_k127_6124634_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000001979 81.0
HFD1_k127_6125862_0 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 562.0
HFD1_k127_6125862_1 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 325.0
HFD1_k127_6125862_2 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 306.0
HFD1_k127_6125862_3 Cytochrome c - - - 0.0000000000002097 75.0
HFD1_k127_6201406_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 591.0
HFD1_k127_6201406_1 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 580.0
HFD1_k127_6201406_10 TIR domain - - - 0.00000000000000000000000000000000000002728 152.0
HFD1_k127_6201406_11 protein serine/threonine phosphatase activity - - - 0.00000000000000000000007643 108.0
HFD1_k127_6201406_2 COG3621 Patatin K06900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 395.0
HFD1_k127_6201406_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 376.0
HFD1_k127_6201406_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 327.0
HFD1_k127_6201406_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 297.0
HFD1_k127_6201406_6 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 300.0
HFD1_k127_6201406_7 protein homooligomerization - - - 0.000000000000000000000000000000000000000000000000000000000000002531 239.0
HFD1_k127_6201406_8 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity K16038 GO:0002682,GO:0002684,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000002934 215.0
HFD1_k127_6201406_9 DinB family - - - 0.0000000000000000000000000000000000000000000000000001261 192.0
HFD1_k127_6212417_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 513.0
HFD1_k127_6212417_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000003826 239.0
HFD1_k127_6228854_0 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 346.0
HFD1_k127_6228854_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006361 290.0
HFD1_k127_6228854_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000002036 221.0
HFD1_k127_6228854_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000001129 156.0
HFD1_k127_6290811_0 hmm pf01609 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 389.0
HFD1_k127_6329823_0 4Fe-4S dicluster domain K00184 - - 0.0 1059.0
HFD1_k127_6329823_1 Polysulphide reductase, NrfD K00185 - - 2.44e-219 688.0
HFD1_k127_6329823_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 369.0
HFD1_k127_6329823_3 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 299.0
HFD1_k127_6329823_4 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 293.0
HFD1_k127_6329823_5 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000007795 222.0
HFD1_k127_6329823_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000001238 194.0
HFD1_k127_6329823_7 Glucokinase K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.000000000000000000000001299 108.0
HFD1_k127_6329823_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000006441 97.0
HFD1_k127_6342780_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 447.0
HFD1_k127_6342780_1 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 415.0
HFD1_k127_6342780_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000003648 101.0
HFD1_k127_6372471_0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0 1128.0
HFD1_k127_6372471_1 ATPase family associated with various cellular activities (AAA) - - - 1.371e-211 679.0
HFD1_k127_6372471_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005176 255.0
HFD1_k127_6372471_3 - - - - 0.0000000000000000000000000000000000000000005508 179.0
HFD1_k127_6372471_4 photosystem II stabilization K02237 - - 0.000003547 61.0
HFD1_k127_6378736_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 430.0
HFD1_k127_6378736_1 PFAM GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 354.0
HFD1_k127_6378736_2 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 313.0
HFD1_k127_6378736_3 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 303.0
HFD1_k127_6378736_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000008036 132.0
HFD1_k127_63894_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.895e-212 664.0
HFD1_k127_63894_1 gag-polyprotein putative aspartyl protease - - - 0.00001694 56.0
HFD1_k127_6396525_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 606.0
HFD1_k127_6396525_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 568.0
HFD1_k127_6396525_10 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000002392 184.0
HFD1_k127_6396525_11 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000002295 153.0
HFD1_k127_6396525_12 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000004651 125.0
HFD1_k127_6396525_14 Choline/ethanolamine kinase - - - 0.00008421 55.0
HFD1_k127_6396525_2 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 443.0
HFD1_k127_6396525_3 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 397.0
HFD1_k127_6396525_4 PFAM Glycosyl transferases group 1 K12995 - 2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 354.0
HFD1_k127_6396525_5 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 350.0
HFD1_k127_6396525_6 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 296.0
HFD1_k127_6396525_7 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003973 280.0
HFD1_k127_6396525_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003618 264.0
HFD1_k127_6396525_9 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000003448 213.0
HFD1_k127_6421949_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 1.008e-301 944.0
HFD1_k127_6421949_1 luciferase - - - 0.0000001065 54.0
HFD1_k127_6421949_2 Domain of unknown function (DUF4440) - - - 0.0001343 50.0
HFD1_k127_642208_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 495.0
HFD1_k127_642208_1 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 496.0
HFD1_k127_642208_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 411.0
HFD1_k127_642208_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 415.0
HFD1_k127_642208_4 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002559 277.0
HFD1_k127_6450837_0 FtsX-like permease family - - - 6.583e-215 709.0
HFD1_k127_6450837_1 siderophore transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 596.0
HFD1_k127_6450837_10 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 339.0
HFD1_k127_6450837_11 - - - - 0.00000000000000000000000009793 112.0
HFD1_k127_6450837_12 - - - - 0.0002789 50.0
HFD1_k127_6450837_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.0005401 43.0
HFD1_k127_6450837_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 562.0
HFD1_k127_6450837_3 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 497.0
HFD1_k127_6450837_4 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 439.0
HFD1_k127_6450837_5 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 430.0
HFD1_k127_6450837_6 COG0644 Dehydrogenases (flavoproteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 417.0
HFD1_k127_6450837_7 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 371.0
HFD1_k127_6450837_8 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 359.0
HFD1_k127_6450837_9 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 357.0
HFD1_k127_6451487_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 419.0
HFD1_k127_6451487_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 301.0
HFD1_k127_6451487_2 COG1230 Co Zn Cd efflux system component K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009109 265.0
HFD1_k127_6451487_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000292 193.0
HFD1_k127_6451487_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000002585 174.0
HFD1_k127_6451487_5 HD domain K07023 - - 0.000000000000000000000000000007239 124.0
HFD1_k127_6451487_6 zinc-ribbon domain - - - 0.0000000000000003051 88.0
HFD1_k127_6473451_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.082e-311 974.0
HFD1_k127_6473451_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 327.0
HFD1_k127_6473451_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000005723 214.0
HFD1_k127_6473451_3 PFAM HD domain - - - 0.0000000000000000000000000000002149 133.0
HFD1_k127_6473451_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0001219 48.0
HFD1_k127_6483463_0 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 334.0
HFD1_k127_6483463_1 Glycogen recognition site of AMP-activated protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 331.0
HFD1_k127_6483463_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000001629 114.0
HFD1_k127_6497053_0 cellulose binding - - - 0.0 1379.0
HFD1_k127_6497053_1 PFAM D-aminoacylase, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 538.0
HFD1_k127_6497053_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000007958 57.0
HFD1_k127_6497053_11 - - - - 0.000006704 49.0
HFD1_k127_6497053_2 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 296.0
HFD1_k127_6497053_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000526 181.0
HFD1_k127_6497053_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000000000000000000002585 173.0
HFD1_k127_6497053_5 - - - - 0.00000000000000000000000000000001623 147.0
HFD1_k127_6497053_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000002291 121.0
HFD1_k127_6497053_7 Glyoxalase-like domain - - - 0.00000000000000000000000552 117.0
HFD1_k127_6497053_8 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000002526 75.0
HFD1_k127_6497681_0 Haem-degrading - - - 0.00000000000000000000000000000000008521 139.0
HFD1_k127_6497681_1 heat shock protein binding - - - 0.0000000004297 70.0
HFD1_k127_6497681_2 heat shock protein binding - - - 0.0000002568 62.0
HFD1_k127_6498492_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 544.0
HFD1_k127_6498492_1 actin binding - - - 0.00000000000000000000000000000000000000000001045 180.0
HFD1_k127_6507786_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 9.312e-269 843.0
HFD1_k127_6507786_1 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 4.576e-210 664.0
HFD1_k127_6507786_10 Domain of unknown function (DUF4388) - - - 0.000001113 59.0
HFD1_k127_6507786_11 - - - - 0.000001818 60.0
HFD1_k127_6507786_12 serine threonine protein kinase K12132 - 2.7.11.1 0.00001687 55.0
HFD1_k127_6507786_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0001469 54.0
HFD1_k127_6507786_2 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 524.0
HFD1_k127_6507786_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 445.0
HFD1_k127_6507786_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 297.0
HFD1_k127_6507786_5 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000001205 269.0
HFD1_k127_6507786_6 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000242 254.0
HFD1_k127_6507786_7 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000001156 243.0
HFD1_k127_6507786_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000003094 201.0
HFD1_k127_6507786_9 Tetratricopeptide repeat - - - 0.000000003282 69.0
HFD1_k127_6521406_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0 1350.0
HFD1_k127_6521406_1 peroxiredoxin activity - - - 8.393e-301 932.0
HFD1_k127_6521406_10 transcriptional regulator - - - 0.00001841 52.0
HFD1_k127_6521406_11 IrrE N-terminal-like domain - - - 0.00062 50.0
HFD1_k127_6521406_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 613.0
HFD1_k127_6521406_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 453.0
HFD1_k127_6521406_4 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 373.0
HFD1_k127_6521406_5 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 362.0
HFD1_k127_6521406_6 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001426 245.0
HFD1_k127_6521406_7 transmembrane transporter activity - - - 0.0000000000000000000000002516 106.0
HFD1_k127_6521406_8 FAD binding domain - - - 0.0000000000002792 72.0
HFD1_k127_6521406_9 sequence-specific DNA binding - - - 0.00000000002139 72.0
HFD1_k127_652265_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 602.0
HFD1_k127_652265_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000004123 172.0
HFD1_k127_652265_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000001453 95.0
HFD1_k127_652265_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000001187 61.0
HFD1_k127_6525276_0 calcium- and calmodulin-responsive adenylate cyclase activity K13735,K20276,K21449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007467 308.0
HFD1_k127_653007_0 Zinc-binding dehydrogenase - - - 1.5e-286 897.0
HFD1_k127_653007_1 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 391.0
HFD1_k127_653007_2 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 331.0
HFD1_k127_653007_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001535 276.0
HFD1_k127_653007_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000003834 225.0
HFD1_k127_653007_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000005653 209.0
HFD1_k127_653007_6 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000009073 169.0
HFD1_k127_6535236_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 371.0
HFD1_k127_6535236_2 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.0000000000000000000000271 105.0
HFD1_k127_6543849_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 9.355e-265 842.0
HFD1_k127_6543849_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177,K03483 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000005203 186.0
HFD1_k127_6543849_2 Putative peptidoglycan binding domain - - - 0.0000001356 58.0
HFD1_k127_6543849_3 Modulates RecA activity K03565 - - 0.0000001476 60.0
HFD1_k127_6581085_0 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.00000000000000000006955 106.0
HFD1_k127_6581085_2 Alpha-L-rhamnosidase - - - 0.0000000000002011 85.0
HFD1_k127_6606319_0 Glycosyltransferase 36 associated - - - 0.0 2636.0
HFD1_k127_6606319_1 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001282 290.0
HFD1_k127_6606319_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000002051 201.0
HFD1_k127_6606319_3 FecR protein - - - 0.00000000000000000000000000000000000000000000000000006055 198.0
HFD1_k127_6606319_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000009191 162.0
HFD1_k127_6606319_5 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000001036 149.0
HFD1_k127_6613444_0 cellulose binding - - - 0.0 1314.0
HFD1_k127_6613444_1 Domain of unknown function (DUF5117) - - - 2.163e-297 934.0
HFD1_k127_6613444_2 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 496.0
HFD1_k127_6613444_3 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 263.0
HFD1_k127_6613444_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000002849 257.0
HFD1_k127_6613444_5 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005562 267.0
HFD1_k127_6613444_6 Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions K03671 - - 0.0000000002753 61.0
HFD1_k127_6613444_7 aminopeptidase activity - - - 0.0000344 48.0
HFD1_k127_6617196_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0004205 51.0
HFD1_k127_6617196_1 Protein of unknown function (DUF2662) - - - 0.0004327 49.0
HFD1_k127_6632766_0 phage tail tape measure protein - - - 5.416e-261 833.0
HFD1_k127_6632766_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 625.0
HFD1_k127_6632766_10 Glycosyl hydrolase 101 beta sandwich domain - - - 0.0004828 53.0
HFD1_k127_6632766_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003202 299.0
HFD1_k127_6632766_3 Macrocin-O-methyltransferase (TylF) K05303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003481 276.0
HFD1_k127_6632766_4 PFAM Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000759 261.0
HFD1_k127_6632766_5 HYR domain - - - 0.00000000000000000000000000000000000000003856 172.0
HFD1_k127_6632766_6 - - - - 0.00000000000000000000000000000000002621 146.0
HFD1_k127_6632766_7 Cephalosporin hydroxylase - - - 0.000000000000000000000000000001967 123.0
HFD1_k127_6632766_8 - - - - 0.000000000000009597 78.0
HFD1_k127_6650113_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 446.0
HFD1_k127_6650113_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 308.0
HFD1_k127_6650113_2 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001632 271.0
HFD1_k127_6650113_3 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000003538 228.0
HFD1_k127_6650113_4 Sporulation protein SPS19 K13237 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0007049,GO:0008150,GO:0008152,GO:0008670,GO:0009056,GO:0009062,GO:0009653,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0031907,GO:0031974,GO:0032502,GO:0032505,GO:0032787,GO:0034293,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046395,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:1901575,GO:1903046 1.3.1.34 0.000000000000000000000000000000000000000008776 156.0
HFD1_k127_6650113_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000708 144.0
HFD1_k127_6650113_6 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000005088 112.0
HFD1_k127_6665992_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.317e-219 694.0
HFD1_k127_6665992_1 HELICc2 K03722 - 3.6.4.12 1.739e-195 629.0
HFD1_k127_6665992_10 Lecithin:cholesterol acyltransferase - - - 0.00000000000000000000000000000000000000000000000003147 197.0
HFD1_k127_6665992_11 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000003982 179.0
HFD1_k127_6665992_12 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000316 134.0
HFD1_k127_6665992_13 Acyltransferase family - - - 0.0000000000000000000000197 114.0
HFD1_k127_6665992_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 560.0
HFD1_k127_6665992_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 467.0
HFD1_k127_6665992_4 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 382.0
HFD1_k127_6665992_5 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 363.0
HFD1_k127_6665992_6 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 308.0
HFD1_k127_6665992_7 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001065 283.0
HFD1_k127_6665992_8 peptidyl-tyrosine sulfation K03217,K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000152 274.0
HFD1_k127_6665992_9 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000625 217.0
HFD1_k127_6679489_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.542e-198 628.0
HFD1_k127_6679489_1 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 565.0
HFD1_k127_6679489_10 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000002153 237.0
HFD1_k127_6679489_11 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000007714 202.0
HFD1_k127_6679489_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000001116 191.0
HFD1_k127_6679489_13 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000001132 183.0
HFD1_k127_6679489_14 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000396 178.0
HFD1_k127_6679489_15 Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000152 173.0
HFD1_k127_6679489_16 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000005266 165.0
HFD1_k127_6679489_17 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000009603 136.0
HFD1_k127_6679489_18 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000001633 128.0
HFD1_k127_6679489_19 amine dehydrogenase activity - - - 0.0000000000000000000000000000005228 133.0
HFD1_k127_6679489_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 537.0
HFD1_k127_6679489_20 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.0000000000000000000000001922 109.0
HFD1_k127_6679489_21 Biotin-requiring enzyme - - - 0.000000000000000000001289 103.0
HFD1_k127_6679489_22 - - - - 0.0000205 50.0
HFD1_k127_6679489_23 - - - - 0.00005667 50.0
HFD1_k127_6679489_3 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 501.0
HFD1_k127_6679489_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 411.0
HFD1_k127_6679489_5 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 349.0
HFD1_k127_6679489_6 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 348.0
HFD1_k127_6679489_7 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 316.0
HFD1_k127_6679489_8 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003884 276.0
HFD1_k127_6679489_9 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000003552 239.0
HFD1_k127_6712270_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000005598 231.0
HFD1_k127_6712270_1 IMG reference gene - - - 0.0000000000000000000000000000000000000000008317 171.0
HFD1_k127_6718177_0 Multicopper oxidase - - - 5.665e-286 912.0
HFD1_k127_6718177_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 572.0
HFD1_k127_6718177_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 447.0
HFD1_k127_6718177_3 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000000000000000000004107 194.0
HFD1_k127_6718177_4 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000526 169.0
HFD1_k127_6718177_5 Multicopper oxidase - - - 0.00000000000000000000000002484 119.0
HFD1_k127_6718177_6 Cation transport ATPase K17686 - 3.6.3.54 0.000008002 56.0
HFD1_k127_6726431_0 Replicative DNA helicase K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 440.0
HFD1_k127_6726431_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 404.0
HFD1_k127_6726431_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001786 151.0
HFD1_k127_6726431_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000558 112.0
HFD1_k127_6726431_12 protein with SCP PR1 domains - - - 0.0000000000000000000002275 102.0
HFD1_k127_6726431_13 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000844 98.0
HFD1_k127_6726431_14 TIGRFAM TonB family K03832 - - 0.00000000000000000003841 94.0
HFD1_k127_6726431_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000007651 75.0
HFD1_k127_6726431_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 337.0
HFD1_k127_6726431_3 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000003403 228.0
HFD1_k127_6726431_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000002447 198.0
HFD1_k127_6726431_5 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000003168 172.0
HFD1_k127_6726431_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000005422 172.0
HFD1_k127_6726431_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000003618 166.0
HFD1_k127_6726431_8 S1/P1 Nuclease - - - 0.00000000000000000000000000000000000000114 160.0
HFD1_k127_6726431_9 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000001052 146.0
HFD1_k127_6765354_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 476.0
HFD1_k127_6770880_0 Tricorn protease C1 domain K08676 - - 0.0 1334.0
HFD1_k127_6770880_1 acetyltransferase - - - 0.0000000000000000000000000005583 115.0
HFD1_k127_6775358_0 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000001641 188.0
HFD1_k127_6775358_1 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000004806 169.0
HFD1_k127_6775358_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000004518 139.0
HFD1_k127_6775358_3 Histidine kinase - - - 0.00000000000000000000000000000005396 136.0
HFD1_k127_6775358_4 D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.000000941 56.0
HFD1_k127_6775358_5 DnaJ molecular chaperone homology domain K19371 - - 0.000001683 61.0
HFD1_k127_6779857_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1564.0
HFD1_k127_6779857_1 Phosphate acyltransferases K01897 - 6.2.1.3 8.295e-231 743.0
HFD1_k127_6779857_10 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000007914 177.0
HFD1_k127_6779857_11 BON domain - - - 0.000000000000000000000000000000000000000002037 164.0
HFD1_k127_6779857_12 - - - - 0.000000000000000000000000000000000006603 142.0
HFD1_k127_6779857_13 Sigma-70 region 2 K03088 - - 0.0000000000000000007096 93.0
HFD1_k127_6779857_14 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000001637 60.0
HFD1_k127_6779857_15 Putative adhesin - - - 0.00000003242 65.0
HFD1_k127_6779857_16 Pfam:N_methyl_2 - - - 0.000003391 56.0
HFD1_k127_6779857_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 463.0
HFD1_k127_6779857_3 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 463.0
HFD1_k127_6779857_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 414.0
HFD1_k127_6779857_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 380.0
HFD1_k127_6779857_6 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 375.0
HFD1_k127_6779857_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 353.0
HFD1_k127_6779857_8 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000003198 225.0
HFD1_k127_6779857_9 - - - - 0.00000000000000000000000000000000000000000000000000578 203.0
HFD1_k127_6805684_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.377e-267 831.0
HFD1_k127_6805684_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 568.0
HFD1_k127_6805684_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000006055 156.0
HFD1_k127_6805684_11 Domain of unknown function (DUF4347) - - - 0.00000000000005515 87.0
HFD1_k127_6805684_12 PFAM CHRD domain containing protein - - - 0.0000000000003788 84.0
HFD1_k127_6805684_13 zinc metalloprotease K11749 - - 0.000000000000749 76.0
HFD1_k127_6805684_14 Reeler domain - - - 0.00000000009312 76.0
HFD1_k127_6805684_15 Proprotein convertase P-domain - - - 0.000000005777 70.0
HFD1_k127_6805684_2 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 548.0
HFD1_k127_6805684_3 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 393.0
HFD1_k127_6805684_4 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 337.0
HFD1_k127_6805684_5 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 319.0
HFD1_k127_6805684_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 299.0
HFD1_k127_6805684_7 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 303.0
HFD1_k127_6805684_8 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 310.0
HFD1_k127_6805684_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005019 257.0
HFD1_k127_6821508_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000194 289.0
HFD1_k127_6821508_1 - - - - 0.00000000001934 68.0
HFD1_k127_6821508_2 - - - - 0.00000000006455 65.0
HFD1_k127_6832579_0 FtsX-like permease family - - - 7.929e-243 776.0
HFD1_k127_6832579_1 MacB-like periplasmic core domain - - - 1.199e-218 704.0
HFD1_k127_6832579_2 efflux transmembrane transporter activity K02004 - - 5.201e-204 662.0
HFD1_k127_6832579_3 MacB-like periplasmic core domain - - - 3.829e-202 654.0
HFD1_k127_6832579_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 591.0
HFD1_k127_6832579_5 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 565.0
HFD1_k127_6832579_6 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 558.0
HFD1_k127_6832579_7 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 488.0
HFD1_k127_6832579_8 Belongs to the UPF0312 family - - - 0.000000000000000000000000005609 117.0
HFD1_k127_6832579_9 efflux transmembrane transporter activity - - - 0.000000000001381 69.0
HFD1_k127_6836761_0 Protein kinase domain K12132 - 2.7.11.1 3.451e-211 689.0
HFD1_k127_6836761_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000001687 202.0
HFD1_k127_6836761_2 YndJ-like protein - - - 0.00000000000000000000000000000000000000004389 166.0
HFD1_k127_6836761_3 - - - - 0.00000000000000000000000008267 116.0
HFD1_k127_6844751_0 L-threonylcarbamoyladenylate synthase K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000005267 237.0
HFD1_k127_6844751_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000008946 242.0
HFD1_k127_6844751_2 tRNA threonylcarbamoyladenosine modification K06925,K07102 - 2.7.1.221 0.00000000000000000000000000000000000006251 149.0
HFD1_k127_6844751_3 tRNA threonylcarbamoyladenosine modification K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - 0.000000000000000000006794 100.0
HFD1_k127_6844751_4 O-sialoglycoprotein endopeptidase. Source PGD - - - 0.00000006263 54.0
HFD1_k127_6857601_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0 1242.0
HFD1_k127_6857601_1 cellulose binding - - - 0.0 1081.0
HFD1_k127_6857601_2 ribosome binding - - - 1.032e-234 761.0
HFD1_k127_6857601_3 ATPase involved in DNA repair - - - 3.279e-220 725.0
HFD1_k127_6857601_4 - - - - 3.107e-194 621.0
HFD1_k127_6857601_5 Isoleucyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 587.0
HFD1_k127_6857601_7 Common central domain of tyrosinase K00505 - 1.14.18.1 0.0000000000000000000000000000000000000000000000132 191.0
HFD1_k127_6857601_8 - - - - 0.0000000000001328 77.0
HFD1_k127_6862756_0 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 478.0
HFD1_k127_6871017_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.441e-285 885.0
HFD1_k127_6871017_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 572.0
HFD1_k127_6871017_10 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 358.0
HFD1_k127_6871017_11 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 296.0
HFD1_k127_6871017_12 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001865 286.0
HFD1_k127_6871017_13 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000002616 239.0
HFD1_k127_6871017_14 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001803 235.0
HFD1_k127_6871017_15 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000003322 252.0
HFD1_k127_6871017_16 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000001451 165.0
HFD1_k127_6871017_17 Radical SAM superfamily K22226 - - 0.00000000000000000000000000000000000152 151.0
HFD1_k127_6871017_18 Histidine kinase - - - 0.0000000000000000000000000000000001445 151.0
HFD1_k127_6871017_19 membrane - - - 0.0000000000000000000000000000000002704 134.0
HFD1_k127_6871017_2 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 565.0
HFD1_k127_6871017_20 Redoxin - - - 0.000000000000000000000000000000002307 134.0
HFD1_k127_6871017_21 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000001277 100.0
HFD1_k127_6871017_22 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000006834 95.0
HFD1_k127_6871017_23 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000003132 71.0
HFD1_k127_6871017_24 Tricorn protease homolog - - - 0.0000000009741 60.0
HFD1_k127_6871017_26 SMART Transport-associated and nodulation region K04065 - - 0.00000007006 64.0
HFD1_k127_6871017_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 550.0
HFD1_k127_6871017_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 490.0
HFD1_k127_6871017_5 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 455.0
HFD1_k127_6871017_6 Carboxymethylenebutenolidase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 450.0
HFD1_k127_6871017_7 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 443.0
HFD1_k127_6871017_8 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 380.0
HFD1_k127_6871017_9 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 360.0
HFD1_k127_6915673_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001993 255.0
HFD1_k127_6915673_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000003013 188.0
HFD1_k127_6933341_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 3.648e-214 675.0
HFD1_k127_6933341_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 516.0
HFD1_k127_6933341_10 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000002249 165.0
HFD1_k127_6933341_11 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000006101 155.0
HFD1_k127_6933341_12 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K13819 - - 0.000000000000000000000001094 107.0
HFD1_k127_6933341_13 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000002449 115.0
HFD1_k127_6933341_14 Polysaccharide biosynthesis protein K12454 - 5.1.3.10 0.00000000000000000002798 102.0
HFD1_k127_6933341_15 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000001046 81.0
HFD1_k127_6933341_16 Protein of unknown function (DUF3108) - - - 0.000000000001603 78.0
HFD1_k127_6933341_17 HEAT repeat - - - 0.0000002284 61.0
HFD1_k127_6933341_2 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 458.0
HFD1_k127_6933341_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 416.0
HFD1_k127_6933341_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000139 275.0
HFD1_k127_6933341_5 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003494 265.0
HFD1_k127_6933341_6 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000001574 251.0
HFD1_k127_6933341_7 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000002489 216.0
HFD1_k127_6933341_8 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000000000000000000000000000000000000000000000000000000165 210.0
HFD1_k127_6933341_9 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000007681 185.0
HFD1_k127_6938447_0 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 431.0
HFD1_k127_6938447_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 364.0
HFD1_k127_6938447_10 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000005549 115.0
HFD1_k127_6938447_11 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000000000000000003548 104.0
HFD1_k127_6938447_12 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000831 90.0
HFD1_k127_6938447_13 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000002246 81.0
HFD1_k127_6938447_14 Virulence factor BrkB - - - 0.0000000000002695 80.0
HFD1_k127_6938447_15 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.000000004682 61.0
HFD1_k127_6938447_16 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.00054 51.0
HFD1_k127_6938447_2 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 314.0
HFD1_k127_6938447_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 319.0
HFD1_k127_6938447_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000002088 212.0
HFD1_k127_6938447_5 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000104 190.0
HFD1_k127_6938447_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000001079 184.0
HFD1_k127_6938447_7 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000008681 171.0
HFD1_k127_6938447_8 LemA family K03744 - - 0.00000000000000000000000000000000000000000008394 166.0
HFD1_k127_6938447_9 BMC K04027 - - 0.0000000000000000000000000000000001892 133.0
HFD1_k127_6939897_0 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 540.0
HFD1_k127_6939897_1 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 406.0
HFD1_k127_6939897_2 Scaffold protein Nfu/NifU N terminal - - - 0.00000000000000000000000000000000000000000000000000007007 193.0
HFD1_k127_6939897_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004567,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015923,GO:0016052,GO:0016787,GO:0016798,GO:0016985,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0071554,GO:0071704,GO:1901575 3.2.1.78 0.0000000000000000000000000000000000000000000000000006762 205.0
HFD1_k127_6941540_0 DEAD DEAH box helicase K03724 - - 1.082e-212 670.0
HFD1_k127_6941540_1 Peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 334.0
HFD1_k127_6941540_2 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000006449 205.0
HFD1_k127_6963039_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 535.0
HFD1_k127_6963039_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001967 295.0
HFD1_k127_6963039_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18302 - - 0.000000000000000000000000000000000000000000000000000000000000000000001933 251.0
HFD1_k127_6980940_0 Beta-xylosidase K01198 - 3.2.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 577.0
HFD1_k127_6980940_1 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 569.0
HFD1_k127_6980940_10 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000009305 154.0
HFD1_k127_6980940_11 Protein of unknown function (DUF1440) K08996 - - 0.0000000000000000000000000000000707 131.0
HFD1_k127_6980940_12 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000004158 100.0
HFD1_k127_6980940_2 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 590.0
HFD1_k127_6980940_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 555.0
HFD1_k127_6980940_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 427.0
HFD1_k127_6980940_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 369.0
HFD1_k127_6980940_6 Alpha-aspartyl dipeptidase-like K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 297.0
HFD1_k127_6980940_7 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000001956 217.0
HFD1_k127_6980940_8 SCO1/SenC K07152,K08976 - - 0.000000000000000000000000000000000000000000000000000000000001082 220.0
HFD1_k127_6980940_9 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000000000000000000000004678 198.0
HFD1_k127_6991098_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 471.0
HFD1_k127_6991098_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 431.0
HFD1_k127_6991098_2 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000006442 237.0
HFD1_k127_6991098_3 Cytochrome c - - - 0.000000000000000000000000000000000003577 147.0
HFD1_k127_6991098_4 cell redox homeostasis K03671 - - 0.00000000009722 66.0
HFD1_k127_6997370_0 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 619.0
HFD1_k127_6997370_1 sigma-54 factor interaction domain-containing protein K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 412.0
HFD1_k127_6997370_2 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 306.0
HFD1_k127_6997370_3 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 307.0
HFD1_k127_6997370_4 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000000000000000000000000000000000000000000000000000003788 215.0
HFD1_k127_6997370_5 Psort location CytoplasmicMembrane, score - - - 0.000000000000000002659 96.0
HFD1_k127_6997370_6 Pfam:N_methyl_2 - - - 0.00000000000000001674 92.0
HFD1_k127_6997370_7 Pfam:N_methyl_2 - - - 0.00000000000000006177 87.0
HFD1_k127_6997370_8 Pfam:N_methyl_2 - - - 0.0000000000000002026 87.0
HFD1_k127_6997370_9 COG1943 Transposase and inactivated derivatives - - - 0.00006573 53.0
HFD1_k127_700590_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 526.0
HFD1_k127_700590_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 385.0
HFD1_k127_700590_10 peptidyl-tyrosine sulfation - - - 0.00000006537 64.0
HFD1_k127_700590_2 Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000002666 269.0
HFD1_k127_700590_3 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008511 257.0
HFD1_k127_700590_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000004026 194.0
HFD1_k127_700590_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000009373 185.0
HFD1_k127_700590_6 O-Antigen ligase K02847 - - 0.00000000000000000000000000000002274 141.0
HFD1_k127_700590_7 NAD-dependent K08678 - 4.1.1.35 0.0000000000000000000000000001594 116.0
HFD1_k127_700590_8 PQQ enzyme repeat - - - 0.00000000000000000000000798 115.0
HFD1_k127_700590_9 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000001367 97.0
HFD1_k127_7033053_0 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 332.0
HFD1_k127_7033053_1 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 331.0
HFD1_k127_7033053_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
HFD1_k127_7033053_3 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000001413 206.0
HFD1_k127_7033053_4 HYR domain - - - 0.000000000000000000000000000000003868 133.0
HFD1_k127_7034132_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1051.0
HFD1_k127_7034132_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 408.0
HFD1_k127_7034132_2 Peptidase M14, carboxypeptidase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 400.0
HFD1_k127_7034132_3 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 357.0
HFD1_k127_7034132_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 358.0
HFD1_k127_7034132_5 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000002091 202.0
HFD1_k127_7034132_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000002104 74.0
HFD1_k127_7107384_0 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003994 270.0
HFD1_k127_7143082_0 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 5.261e-303 945.0
HFD1_k127_7143082_1 alginic acid biosynthetic process - - - 2.066e-218 764.0
HFD1_k127_7143082_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 332.0
HFD1_k127_7143082_11 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 322.0
HFD1_k127_7143082_12 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003327 265.0
HFD1_k127_7143082_13 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000001239 232.0
HFD1_k127_7143082_14 TonB dependent receptor K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000005642 248.0
HFD1_k127_7143082_15 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000005707 233.0
HFD1_k127_7143082_16 oxidoreductase activity - - - 0.0000000000000000000000000000000000003696 161.0
HFD1_k127_7143082_17 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000002318 116.0
HFD1_k127_7143082_18 serine-type endopeptidase activity K14645,K20276 - - 0.00000000000000000000001139 112.0
HFD1_k127_7143082_19 SMI1 / KNR4 family (SUKH-1) - - - 0.0000000000000000000006255 102.0
HFD1_k127_7143082_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 586.0
HFD1_k127_7143082_20 - - - - 0.0000000000000000006451 90.0
HFD1_k127_7143082_21 AraC-like ligand binding domain - - - 0.00000000000000002399 87.0
HFD1_k127_7143082_22 Protein of unknown function (DUF1176) - - - 0.00000003274 62.0
HFD1_k127_7143082_3 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 544.0
HFD1_k127_7143082_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 535.0
HFD1_k127_7143082_5 proline dipeptidase activity K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 496.0
HFD1_k127_7143082_6 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 488.0
HFD1_k127_7143082_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 443.0
HFD1_k127_7143082_8 domain protein K02674,K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 412.0
HFD1_k127_7143082_9 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 362.0
HFD1_k127_7238726_0 serine-type peptidase activity - - - 0.0 1089.0
HFD1_k127_7238726_1 ThiS family K21029,K21147 - 2.7.7.80,2.8.1.11 9.258e-197 624.0
HFD1_k127_7238726_2 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001031 263.0
HFD1_k127_7238726_3 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003223 252.0
HFD1_k127_7238726_4 JAB/MPN domain - - - 0.000000000000000000000000000000000000002386 154.0
HFD1_k127_7238726_5 Cys Met metabolism K01739 - 2.5.1.48 0.00000000000000000000000000000000002158 138.0
HFD1_k127_7238726_6 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.000000000000000003948 85.0
HFD1_k127_7242818_0 Male sterility protein K01897 - 6.2.1.3 2.652e-250 799.0
HFD1_k127_7242818_1 spectrin binding - - - 0.00000000291 61.0
HFD1_k127_7244015_0 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 358.0
HFD1_k127_7244015_1 DinB family - - - 0.000000000000000000003945 99.0
HFD1_k127_7265379_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 577.0
HFD1_k127_7265379_1 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 348.0
HFD1_k127_7265379_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 325.0
HFD1_k127_727450_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 420.0
HFD1_k127_727450_1 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 433.0
HFD1_k127_727450_2 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 400.0
HFD1_k127_727450_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004623 271.0
HFD1_k127_727450_4 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000005152 187.0
HFD1_k127_727450_5 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000376 160.0
HFD1_k127_7302111_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 442.0
HFD1_k127_7302111_1 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002527 283.0
HFD1_k127_7317564_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1223.0
HFD1_k127_7317564_1 TonB dependent receptor K16090 - - 1.978e-224 719.0
HFD1_k127_7317564_10 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001149 258.0
HFD1_k127_7317564_11 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000005648 214.0
HFD1_k127_7317564_12 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000001154 203.0
HFD1_k127_7317564_13 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000001824 184.0
HFD1_k127_7317564_14 Domain of unknown function (DUF4114) - - - 0.0000000000000000000000000000000000000000000002097 194.0
HFD1_k127_7317564_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000002455 169.0
HFD1_k127_7317564_16 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000004365 166.0
HFD1_k127_7317564_17 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000009552 141.0
HFD1_k127_7317564_18 Parallel beta-helix repeats - - - 0.00000000000000000000000000001912 129.0
HFD1_k127_7317564_19 - - - - 0.0000000000000000000000000001622 132.0
HFD1_k127_7317564_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 497.0
HFD1_k127_7317564_21 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000491 79.0
HFD1_k127_7317564_22 - - - - 0.000001612 50.0
HFD1_k127_7317564_3 Multicopper oxidase K14588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 449.0
HFD1_k127_7317564_4 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 443.0
HFD1_k127_7317564_5 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 431.0
HFD1_k127_7317564_6 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 393.0
HFD1_k127_7317564_7 Phytanoyl-CoA dioxygenase (PhyH) K00477 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 359.0
HFD1_k127_7317564_8 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 327.0
HFD1_k127_7317564_9 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 309.0
HFD1_k127_7321802_0 family UPF0027 K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000003826 244.0
HFD1_k127_7321802_1 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000007328 199.0
HFD1_k127_7321802_2 PFAM HNH endonuclease - - - 0.00000000000000000000000000000006028 133.0
HFD1_k127_7321802_3 nuclear chromosome segregation - - - 0.0000000000000000001923 99.0
HFD1_k127_733260_0 Succinyl-CoA ligase like flavodoxin domain - - - 1.954e-320 1006.0
HFD1_k127_733260_1 glutamate--cysteine ligase - - - 1.676e-235 744.0
HFD1_k127_733260_10 pectinesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004872 243.0
HFD1_k127_733260_11 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000006065 209.0
HFD1_k127_733260_12 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000001302 210.0
HFD1_k127_733260_13 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000002875 204.0
HFD1_k127_733260_14 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000008336 204.0
HFD1_k127_733260_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000008323 145.0
HFD1_k127_733260_16 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000006181 151.0
HFD1_k127_733260_18 Universal stress protein family - - - 0.0000000000000000000000000000000004045 143.0
HFD1_k127_733260_19 Universal stress protein family - - - 0.0000000000000000000000000000001221 129.0
HFD1_k127_733260_2 Subtilase family - - - 1.292e-212 677.0
HFD1_k127_733260_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000007518 118.0
HFD1_k127_733260_21 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000007884 108.0
HFD1_k127_733260_22 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000002384 100.0
HFD1_k127_733260_23 AMP binding - - - 0.000000000000000159 90.0
HFD1_k127_733260_24 Peptidoglycan-binding domain 1 protein - - - 0.00000000009605 72.0
HFD1_k127_733260_25 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000005534 65.0
HFD1_k127_733260_26 - - - - 0.00000002801 60.0
HFD1_k127_733260_3 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 622.0
HFD1_k127_733260_4 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 599.0
HFD1_k127_733260_5 Zinc-binding dehydrogenase K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 576.0
HFD1_k127_733260_6 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 443.0
HFD1_k127_733260_7 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 414.0
HFD1_k127_733260_8 PFAM Response regulator receiver domain K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 357.0
HFD1_k127_733260_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 325.0
HFD1_k127_7357863_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 4.532e-248 779.0
HFD1_k127_7357863_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 471.0
HFD1_k127_7357863_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 443.0
HFD1_k127_7357863_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 297.0
HFD1_k127_7357863_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000001713 214.0
HFD1_k127_7357863_5 Histidine kinase K02668,K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001249 218.0
HFD1_k127_7357863_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000005858 196.0
HFD1_k127_7357863_7 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000001574 192.0
HFD1_k127_7357863_8 Outer membrane efflux protein - - - 0.00000000000000000000005315 115.0
HFD1_k127_7357863_9 Preprotein translocase SecG subunit K03075 - - 0.000000007705 61.0
HFD1_k127_7386970_0 - K17285 - - 0.0 1256.0
HFD1_k127_7386970_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.502e-270 859.0
HFD1_k127_7386970_10 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 374.0
HFD1_k127_7386970_11 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 336.0
HFD1_k127_7386970_12 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 321.0
HFD1_k127_7386970_13 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 292.0
HFD1_k127_7386970_14 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000138 299.0
HFD1_k127_7386970_15 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 277.0
HFD1_k127_7386970_16 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001327 249.0
HFD1_k127_7386970_17 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000009809 200.0
HFD1_k127_7386970_18 Tellurite resistance protein TehB K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000008482 191.0
HFD1_k127_7386970_19 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.0000000000000000000000000005849 124.0
HFD1_k127_7386970_2 carbamoyl transferase, NodU family K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 533.0
HFD1_k127_7386970_20 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000006482 123.0
HFD1_k127_7386970_21 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000001111 95.0
HFD1_k127_7386970_22 PD-(D/E)XK nuclease superfamily - - - 0.000000000009522 69.0
HFD1_k127_7386970_23 Glycosyl transferases group 1 - - - 0.0000000008367 70.0
HFD1_k127_7386970_24 Glycosyltransferase like family 2 K07011,K20444 - - 0.00000001341 66.0
HFD1_k127_7386970_25 lipolytic protein G-D-S-L family K19172 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000006419 57.0
HFD1_k127_7386970_3 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784,K08678,K08679 - 4.1.1.35,4.2.1.46,5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 515.0
HFD1_k127_7386970_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 528.0
HFD1_k127_7386970_5 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 448.0
HFD1_k127_7386970_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 411.0
HFD1_k127_7386970_7 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 407.0
HFD1_k127_7386970_8 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 384.0
HFD1_k127_7386970_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 362.0
HFD1_k127_7395709_0 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 370.0
HFD1_k127_7395709_1 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000006109 243.0
HFD1_k127_7396058_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 565.0
HFD1_k127_7396058_1 DDE superfamily endonuclease - - - 0.000000000002186 66.0
HFD1_k127_7448035_0 Heat shock 70 kDa protein K04043 - - 1.432e-233 737.0
HFD1_k127_7448035_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 417.0
HFD1_k127_7448035_3 HrcA protein C terminal domain K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002487 263.0
HFD1_k127_7448035_4 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000002535 200.0
HFD1_k127_7448035_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000006261 129.0
HFD1_k127_7453265_0 amino acid - - - 2.864e-260 816.0
HFD1_k127_7453265_1 amino acid - - - 7.79e-258 810.0
HFD1_k127_7453265_10 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000004733 168.0
HFD1_k127_7453265_11 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000001589 159.0
HFD1_k127_7453265_12 Probable zinc-ribbon domain - - - 0.000000000000000000000000000007962 122.0
HFD1_k127_7453265_13 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000003393 116.0
HFD1_k127_7453265_14 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000009366 104.0
HFD1_k127_7453265_15 - - - - 0.000000000000001156 87.0
HFD1_k127_7453265_16 BON domain K04065 - - 0.0004357 50.0
HFD1_k127_7453265_17 RNA polymerase-associated protein CTR9 homolog K15176 GO:0000122,GO:0000428,GO:0000785,GO:0000993,GO:0001098,GO:0001099,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0008023,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009909,GO:0009910,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0016020,GO:0016043,GO:0016569,GO:0016570,GO:0016571,GO:0016591,GO:0016593,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0030880,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032270,GO:0032784,GO:0032786,GO:0032968,GO:0032991,GO:0033043,GO:0033044,GO:0034243,GO:0034968,GO:0035327,GO:0036211,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048581,GO:0048831,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051569,GO:0051571,GO:0055029,GO:0060255,GO:0061695,GO:0065007,GO:0070013,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0080182,GO:1901564,GO:1902275,GO:1902494,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1905269,GO:1990234,GO:2000026,GO:2000112,GO:2000113,GO:2000241,GO:2000242,GO:2001141,GO:2001252 - 0.0009232 51.0
HFD1_k127_7453265_2 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 557.0
HFD1_k127_7453265_3 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 495.0
HFD1_k127_7453265_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 472.0
HFD1_k127_7453265_5 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 391.0
HFD1_k127_7453265_6 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 374.0
HFD1_k127_7453265_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 364.0
HFD1_k127_7453265_8 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000693 285.0
HFD1_k127_7453265_9 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001508 259.0
HFD1_k127_7453919_0 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000005114 182.0
HFD1_k127_7453919_1 glycosyltransferase involved in LPS biosynthesis K07270 - - 0.00000000000000000000000000000000000000000002911 175.0
HFD1_k127_7453919_2 Multicopper oxidase - - - 0.0000000000000000000001202 108.0
HFD1_k127_7501676_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 601.0
HFD1_k127_7501676_1 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 520.0
HFD1_k127_7501676_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000002693 126.0
HFD1_k127_7501676_3 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.000001155 57.0
HFD1_k127_7502596_0 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 3.131e-254 789.0
HFD1_k127_7502596_1 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 595.0
HFD1_k127_7502596_10 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 369.0
HFD1_k127_7502596_11 neuron death in response to oxidative stress K01173,K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 357.0
HFD1_k127_7502596_12 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 302.0
HFD1_k127_7502596_13 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 290.0
HFD1_k127_7502596_14 DNA/RNA non-specific endonuclease K01173 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001951 290.0
HFD1_k127_7502596_15 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000003066 255.0
HFD1_k127_7502596_16 Amidohydrolase family K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000003683 198.0
HFD1_k127_7502596_17 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.0000000000000000000000000000000000000000000000000000006331 222.0
HFD1_k127_7502596_18 NifU-like N terminal domain K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000000000001083 196.0
HFD1_k127_7502596_19 domain protein - - - 0.00000000000000000000000000000000000000000000006404 196.0
HFD1_k127_7502596_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 586.0
HFD1_k127_7502596_20 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000006424 162.0
HFD1_k127_7502596_21 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000007966 164.0
HFD1_k127_7502596_22 domain protein - - - 0.0000000000000000000000000000000000000007848 173.0
HFD1_k127_7502596_23 Lamin Tail Domain - - - 0.00000000000000000000000000000000001208 159.0
HFD1_k127_7502596_24 transcriptional regulator - - - 0.0000000000000000000000001348 111.0
HFD1_k127_7502596_25 Peptidase, M56 - - - 0.000000923 61.0
HFD1_k127_7502596_3 PFAM Peptidase S10, serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 553.0
HFD1_k127_7502596_4 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 483.0
HFD1_k127_7502596_5 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 461.0
HFD1_k127_7502596_6 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 456.0
HFD1_k127_7502596_7 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 437.0
HFD1_k127_7502596_8 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 380.0
HFD1_k127_7502596_9 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 361.0
HFD1_k127_7534867_0 Glycosyl hydrolase family 1 K00067 - 1.1.1.133 4.35e-298 930.0
HFD1_k127_7534867_1 Belongs to the glycosyl hydrolase 13 family K21575 - 3.2.1.135 6.132e-290 906.0
HFD1_k127_7534867_10 - - - - 0.000000000000000000000000000000000000000000000000000000005376 202.0
HFD1_k127_7534867_11 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000003576 181.0
HFD1_k127_7534867_12 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000211 148.0
HFD1_k127_7534867_13 BtpA family K06971 - - 0.0000000000000000000000000000000000367 138.0
HFD1_k127_7534867_14 Domain of unknown function (DUF4190) - - - 0.00000000000003306 83.0
HFD1_k127_7534867_15 Flavin containing amine oxidoreductase - - - 0.00000000000006455 73.0
HFD1_k127_7534867_16 ankyrin repeat K06867 - - 0.000000000001181 79.0
HFD1_k127_7534867_17 Polysaccharide biosynthesis K01991 - - 0.00001349 57.0
HFD1_k127_7534867_18 PFAM Tetratricopeptide repeat - - - 0.0003838 53.0
HFD1_k127_7534867_2 Belongs to the glycosyl hydrolase 2 family - - - 6.839e-254 795.0
HFD1_k127_7534867_3 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 3.743e-206 648.0
HFD1_k127_7534867_4 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 591.0
HFD1_k127_7534867_5 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 508.0
HFD1_k127_7534867_6 PFAM UDP-galactopyranose mutase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 510.0
HFD1_k127_7534867_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 413.0
HFD1_k127_7534867_8 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007958 261.0
HFD1_k127_7534867_9 Uncharacterized conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000002552 211.0
HFD1_k127_7551970_0 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 580.0
HFD1_k127_7551970_1 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 359.0
HFD1_k127_7551970_10 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000002095 129.0
HFD1_k127_7551970_11 - - - - 0.0000000000000000000002703 104.0
HFD1_k127_7551970_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 344.0
HFD1_k127_7551970_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 308.0
HFD1_k127_7551970_4 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 294.0
HFD1_k127_7551970_5 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004986 263.0
HFD1_k127_7551970_6 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000009401 217.0
HFD1_k127_7551970_7 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000001455 222.0
HFD1_k127_7551970_8 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000000000005363 158.0
HFD1_k127_7551970_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000125 136.0
HFD1_k127_7555317_0 dna ligase - - - 2.803e-223 698.0
HFD1_k127_7555317_1 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 578.0
HFD1_k127_7555317_10 peptidyl-tyrosine sulfation K03217,K06872 - - 0.000000000000000000000000000000002116 142.0
HFD1_k127_7555317_11 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000002109 74.0
HFD1_k127_7555317_12 Protein of unknown function (DUF433) - - - 0.000001669 53.0
HFD1_k127_7555317_2 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 395.0
HFD1_k127_7555317_3 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
HFD1_k127_7555317_4 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 383.0
HFD1_k127_7555317_5 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.000000000000000000000000000000000000000000000000000000000000000000000001535 252.0
HFD1_k127_7555317_6 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001328 253.0
HFD1_k127_7555317_7 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000001071 237.0
HFD1_k127_7555317_8 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000000000000000000000000000005954 219.0
HFD1_k127_7555317_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000004646 151.0
HFD1_k127_7588238_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 8.579e-204 642.0
HFD1_k127_7588238_1 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 527.0
HFD1_k127_7588238_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000007158 104.0
HFD1_k127_7588238_11 - - - - 0.000003531 54.0
HFD1_k127_7588238_12 ATP-independent chaperone mediated protein folding K06006 - - 0.00002261 55.0
HFD1_k127_7588238_13 Cytochrome c K00406,K08906 - - 0.00004207 51.0
HFD1_k127_7588238_14 Beta-galactosidase K12308 - 3.2.1.23 0.00007805 56.0
HFD1_k127_7588238_2 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 417.0
HFD1_k127_7588238_3 Arginase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 291.0
HFD1_k127_7588238_4 Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008517 281.0
HFD1_k127_7588238_5 Membrane - - - 0.0000000000000000000000000000000000000000000000001581 197.0
HFD1_k127_7588238_6 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000003086 175.0
HFD1_k127_7588238_7 peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000001144 136.0
HFD1_k127_7588238_8 Sigma-70, region 4 - - - 0.0000000000000000000000000000001227 131.0
HFD1_k127_7588238_9 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000000006705 113.0
HFD1_k127_7599058_0 Sortilin, neurotensin receptor 3, - - - 0.0 1337.0
HFD1_k127_7599058_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.984e-251 798.0
HFD1_k127_7599058_10 Transcriptional repressor, CopY family - - - 0.000000000000000000000000000000000000000001451 159.0
HFD1_k127_7599058_11 - - - - 0.000000000000000000000000000000000000001783 151.0
HFD1_k127_7599058_12 Thiol-disulfide oxidoreductase DCC - - - 0.000000000000000000000000000000000003036 141.0
HFD1_k127_7599058_13 - - - - 0.000000000007837 72.0
HFD1_k127_7599058_14 Transcriptional regulator K07979 - - 0.000000002085 61.0
HFD1_k127_7599058_15 - - - - 0.0000008154 56.0
HFD1_k127_7599058_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 593.0
HFD1_k127_7599058_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 544.0
HFD1_k127_7599058_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 419.0
HFD1_k127_7599058_5 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 380.0
HFD1_k127_7599058_6 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 371.0
HFD1_k127_7599058_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 304.0
HFD1_k127_7599058_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000004606 219.0
HFD1_k127_7599058_9 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000006798 197.0
HFD1_k127_7603428_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 571.0
HFD1_k127_7603428_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001189 285.0
HFD1_k127_7603428_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000004432 164.0
HFD1_k127_7616336_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1692.0
HFD1_k127_7624122_0 Alpha/beta hydrolase family - - - 6.293e-208 666.0
HFD1_k127_7624122_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 607.0
HFD1_k127_7624122_2 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 485.0
HFD1_k127_7624122_3 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 396.0
HFD1_k127_7624122_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 300.0
HFD1_k127_7624122_5 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003488 284.0
HFD1_k127_7624122_6 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000002182 205.0
HFD1_k127_7624122_7 Bacterial regulatory proteins, gntR family - - - 0.000001727 54.0
HFD1_k127_7624122_8 energy transducer activity K03832 - - 0.00001374 57.0
HFD1_k127_7625661_0 Amidohydrolase family K01466 - 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 525.0
HFD1_k127_7625661_1 Belongs to the allantoicase family K01477 - 3.5.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 465.0
HFD1_k127_7625661_10 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000002175 156.0
HFD1_k127_7625661_11 Transthyretin K07127 - 3.5.2.17 0.00000000000000000000000000000000946 132.0
HFD1_k127_7625661_12 Domain of unknown function (DUF4350) - - - 0.000000000000004942 88.0
HFD1_k127_7625661_13 pathogenesis - - - 0.00000000002971 75.0
HFD1_k127_7625661_14 integral membrane protein - - - 0.0000000000393 74.0
HFD1_k127_7625661_15 Domain of unknown function (DUF4129) - - - 0.00000000006398 74.0
HFD1_k127_7625661_16 iron ion homeostasis - - - 0.0000002626 63.0
HFD1_k127_7625661_17 iron ion homeostasis - - - 0.0004786 53.0
HFD1_k127_7625661_3 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 367.0
HFD1_k127_7625661_4 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 318.0
HFD1_k127_7625661_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001832 254.0
HFD1_k127_7625661_6 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008666 248.0
HFD1_k127_7625661_7 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002336 246.0
HFD1_k127_7625661_8 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000001063 220.0
HFD1_k127_7625661_9 Belongs to the allantoicase family K01477 - 3.5.3.4 0.0000000000000000000000000000000000000000002892 165.0
HFD1_k127_7626540_0 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007727 278.0
HFD1_k127_7626540_1 - - - - 0.00000000004782 69.0
HFD1_k127_7626540_2 - - - - 0.00000000008871 64.0
HFD1_k127_7650333_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 451.0
HFD1_k127_7650333_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 312.0
HFD1_k127_7650333_10 - - - - 0.000000000000000000000000000136 117.0
HFD1_k127_7650333_11 Tyrosine phosphatase family - - - 0.000000000000000000005732 100.0
HFD1_k127_7650333_12 AntiSigma factor - - - 0.000000000000000005619 94.0
HFD1_k127_7650333_13 gluconolactonase K01053 - 3.1.1.17 0.0000003761 55.0
HFD1_k127_7650333_14 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00009233 54.0
HFD1_k127_7650333_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002003 277.0
HFD1_k127_7650333_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000003273 161.0
HFD1_k127_7650333_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000275 169.0
HFD1_k127_7650333_5 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000004979 158.0
HFD1_k127_7650333_6 TIR domain - - - 0.000000000000000000000000000000000000002257 160.0
HFD1_k127_7650333_7 oxidoreductase activity - - - 0.000000000000000000000000000000000002039 157.0
HFD1_k127_7650333_8 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000001255 136.0
HFD1_k127_7650333_9 outer membrane efflux protein - - - 0.0000000000000000000000000000000004652 147.0
HFD1_k127_7658464_0 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007509 267.0
HFD1_k127_7658464_1 HD domain - - - 0.000000000000000000000000000000000000000000000634 182.0
HFD1_k127_7658464_2 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.0000000000000000004848 88.0
HFD1_k127_7658464_3 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000001767 81.0
HFD1_k127_7658464_4 STAS domain K06378 - - 0.000004126 54.0
HFD1_k127_7658464_5 ABC-2 type transporter - - - 0.0001291 46.0
HFD1_k127_7665628_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 3.997e-287 910.0
HFD1_k127_7665628_1 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 373.0
HFD1_k127_7665628_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000006312 138.0
HFD1_k127_7665628_3 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000001928 91.0
HFD1_k127_7671620_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.626e-203 643.0
HFD1_k127_7671620_1 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 413.0
HFD1_k127_7671620_10 Belongs to the UPF0374 family K07586 - - 0.0000000000000006125 83.0
HFD1_k127_7671620_11 Fibronectin type 3 domain - - - 0.000000000000006634 86.0
HFD1_k127_7671620_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 295.0
HFD1_k127_7671620_3 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001786 267.0
HFD1_k127_7671620_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004851 250.0
HFD1_k127_7671620_5 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000008798 252.0
HFD1_k127_7671620_6 PFAM Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000001296 187.0
HFD1_k127_7671620_7 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.000000000000000000000000000000000000006925 154.0
HFD1_k127_7671620_8 Permease, YjgP YjgQ - - - 0.000000000000000000000000000001499 136.0
HFD1_k127_7671620_9 - - - - 0.0000000000000000000001418 102.0
HFD1_k127_7699901_0 Prolyl oligopeptidase family - - - 1.419e-265 836.0
HFD1_k127_7699901_1 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 614.0
HFD1_k127_7699901_2 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 606.0
HFD1_k127_7699901_3 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 435.0
HFD1_k127_7699901_4 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000002859 221.0
HFD1_k127_7699901_5 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000001369 173.0
HFD1_k127_7699901_6 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000008948 177.0
HFD1_k127_7699901_7 Lysin motif - - - 0.00000000000000000000000000000000000000007624 158.0
HFD1_k127_7699901_8 Peptidase M64 N-terminus - - - 0.00000000000000000001551 92.0
HFD1_k127_7709025_0 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 509.0
HFD1_k127_7709025_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 470.0
HFD1_k127_7709025_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 361.0
HFD1_k127_7709025_3 PFAM Peptidase M1 membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 348.0
HFD1_k127_7709025_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000002339 200.0
HFD1_k127_7709025_5 Belongs to the 'phage' integrase family K04763 - - 0.000000000002248 69.0
HFD1_k127_7709025_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000001012 65.0
HFD1_k127_7716383_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0 2458.0
HFD1_k127_7716383_1 Peptidoglycan-binding domain 1 protein - - - 0.0 1844.0
HFD1_k127_7716383_2 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 492.0
HFD1_k127_773669_0 Vitamin B12 dependent methionine synthase, activation domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1365.0
HFD1_k127_773669_1 Male sterility protein K01897 - 6.2.1.3 0.0 1304.0
HFD1_k127_773669_10 peptidoglycan catabolic process - - - 0.000000000000000000000000000007728 126.0
HFD1_k127_773669_11 - - - - 0.0000000000000000001413 95.0
HFD1_k127_773669_12 Aminotransferase K00812 - 2.6.1.1 0.00000000000000009178 84.0
HFD1_k127_773669_13 methyltransferase - - - 0.0000000000000002536 89.0
HFD1_k127_773669_14 Peptidase family S41 - - - 0.000004628 60.0
HFD1_k127_773669_2 Domain of unknown function (DUF2088) - - - 7.893e-225 709.0
HFD1_k127_773669_3 Tetratricopeptide repeat - - - 1.821e-196 629.0
HFD1_k127_773669_4 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 307.0
HFD1_k127_773669_5 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000002565 231.0
HFD1_k127_773669_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000008586 213.0
HFD1_k127_773669_7 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001221 211.0
HFD1_k127_773669_8 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000003895 181.0
HFD1_k127_773669_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000001894 172.0
HFD1_k127_774079_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 480.0
HFD1_k127_774079_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 389.0
HFD1_k127_774079_2 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000001831 213.0
HFD1_k127_774079_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000008542 188.0
HFD1_k127_774079_5 - - - - 0.00009953 48.0
HFD1_k127_774079_6 CAAX protease self-immunity K07052 - - 0.0001088 53.0
HFD1_k127_776252_0 Carbamoyltransferase C-terminus K00612 - - 2.252e-244 766.0
HFD1_k127_776252_1 - - - - 0.00000000000004069 74.0
HFD1_k127_7764407_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 496.0
HFD1_k127_7764407_1 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 384.0
HFD1_k127_7764407_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 372.0
HFD1_k127_7764407_3 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000827 209.0
HFD1_k127_7764407_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000001255 146.0
HFD1_k127_7764407_5 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000002244 152.0
HFD1_k127_7764407_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000006742 142.0
HFD1_k127_7764407_7 Belongs to the peptidase S1C family - - - 0.000000000000000004016 98.0
HFD1_k127_7764407_8 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.00000007101 63.0
HFD1_k127_7764407_9 Tetratricopeptide repeat-like domain - - - 0.00006771 53.0
HFD1_k127_7787727_0 serine-type endopeptidase activity K01173,K04771 - 3.4.21.107 0.000000000000000000000000000000003078 145.0
HFD1_k127_7787727_1 ATPase involved in DNA repair K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000004851 137.0
HFD1_k127_7807348_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 3.691e-215 681.0
HFD1_k127_7807348_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 3.122e-213 671.0
HFD1_k127_7807348_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000127 63.0
HFD1_k127_7807348_11 Protein of unknown function (DUF721) - - - 0.00001966 52.0
HFD1_k127_7807348_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 540.0
HFD1_k127_7807348_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 364.0
HFD1_k127_7807348_4 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 319.0
HFD1_k127_7807348_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005581 280.0
HFD1_k127_7807348_6 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000038 252.0
HFD1_k127_7807348_7 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000003014 228.0
HFD1_k127_7807348_8 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000002132 194.0
HFD1_k127_7807348_9 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000000465 151.0
HFD1_k127_7822119_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 563.0
HFD1_k127_7822119_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 492.0
HFD1_k127_7822119_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 482.0
HFD1_k127_7822119_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000004725 257.0
HFD1_k127_7822119_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000003178 153.0
HFD1_k127_7822119_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000006134 96.0
HFD1_k127_7827686_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 437.0
HFD1_k127_7827686_1 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 363.0
HFD1_k127_7827686_2 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 311.0
HFD1_k127_7827686_3 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000002267 152.0
HFD1_k127_7847763_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 526.0
HFD1_k127_7847763_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 498.0
HFD1_k127_7847763_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 361.0
HFD1_k127_7847763_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 338.0
HFD1_k127_7847763_4 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 335.0
HFD1_k127_7847763_5 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.0000000000000000000000000000004612 124.0
HFD1_k127_7847763_6 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000007239 124.0
HFD1_k127_7880124_0 lipopolysaccharide transport K22110 - - 0.0 1191.0
HFD1_k127_7880124_1 choline dehydrogenase activity - - - 1.112e-263 819.0
HFD1_k127_7880124_10 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 452.0
HFD1_k127_7880124_11 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 449.0
HFD1_k127_7880124_12 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 436.0
HFD1_k127_7880124_13 Proline racemase K12658 - 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 431.0
HFD1_k127_7880124_14 Dihydrodipicolinate synthetase family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 416.0
HFD1_k127_7880124_15 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 406.0
HFD1_k127_7880124_16 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 346.0
HFD1_k127_7880124_17 Major intrinsic protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 326.0
HFD1_k127_7880124_18 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 324.0
HFD1_k127_7880124_19 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 322.0
HFD1_k127_7880124_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 9.919e-196 621.0
HFD1_k127_7880124_20 4 iron, 4 sulfur cluster binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 308.0
HFD1_k127_7880124_21 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001773 269.0
HFD1_k127_7880124_22 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000004951 227.0
HFD1_k127_7880124_23 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000001568 230.0
HFD1_k127_7880124_24 Ndr family - - - 0.0000000000000000000000000000000000000000000000000000001525 218.0
HFD1_k127_7880124_25 methyltransferase K05928 - 2.1.1.95 0.000000000000000000000000000000000000000000000000000002213 201.0
HFD1_k127_7880124_26 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000109 184.0
HFD1_k127_7880124_27 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000002316 176.0
HFD1_k127_7880124_28 - - - - 0.000000000000000000000000000000000000001399 152.0
HFD1_k127_7880124_29 PFAM glycine cleavage H-protein - - - 0.000000000000000000000000000000003676 138.0
HFD1_k127_7880124_3 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 597.0
HFD1_k127_7880124_30 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000004007 119.0
HFD1_k127_7880124_31 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0000000000000000000000566 101.0
HFD1_k127_7880124_32 Transglycosylase associated protein - - - 0.00000000000000000000007746 100.0
HFD1_k127_7880124_33 domain protein - - - 0.0000000000000000000002651 112.0
HFD1_k127_7880124_34 hydroperoxide reductase activity - - - 0.00000000000000000001286 94.0
HFD1_k127_7880124_35 domain protein - - - 0.0000000000000000000718 104.0
HFD1_k127_7880124_36 Domain of Unknown Function (DUF350) - - - 0.0000000000000001945 82.0
HFD1_k127_7880124_37 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000404 85.0
HFD1_k127_7880124_38 Transglutaminase-like superfamily - - - 0.0000000000647 78.0
HFD1_k127_7880124_4 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 609.0
HFD1_k127_7880124_40 NAD dependent epimerase dehydratase family protein K01784 - 5.1.3.2 0.00000000097 69.0
HFD1_k127_7880124_41 Transmembrane anti-sigma factor - - - 0.000000005918 61.0
HFD1_k127_7880124_42 Putative zinc-finger - - - 0.0000001698 57.0
HFD1_k127_7880124_43 3D domain - - - 0.000666 50.0
HFD1_k127_7880124_44 Glycosyl transferase family 41 - - - 0.0009247 54.0
HFD1_k127_7880124_5 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 587.0
HFD1_k127_7880124_6 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 567.0
HFD1_k127_7880124_7 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 575.0
HFD1_k127_7880124_8 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 508.0
HFD1_k127_7880124_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 454.0
HFD1_k127_7886285_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1032.0
HFD1_k127_7886285_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 487.0
HFD1_k127_7886285_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000396 178.0
HFD1_k127_7912345_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 430.0
HFD1_k127_7912345_1 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 382.0
HFD1_k127_7912345_2 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 318.0
HFD1_k127_7912345_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 309.0
HFD1_k127_7912345_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004223 284.0
HFD1_k127_7912345_5 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004079 235.0
HFD1_k127_7912345_6 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000003587 226.0
HFD1_k127_7912345_7 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000006236 208.0
HFD1_k127_7912345_8 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000431 174.0
HFD1_k127_7912345_9 Probable zinc-ribbon domain - - - 0.000000000000000000001242 98.0
HFD1_k127_7927059_0 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 483.0
HFD1_k127_7927059_1 YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 376.0
HFD1_k127_7986505_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 556.0
HFD1_k127_7986505_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 516.0
HFD1_k127_7986505_2 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 387.0
HFD1_k127_7986505_3 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 307.0
HFD1_k127_7986505_4 PFAM WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003355 290.0
HFD1_k127_7986505_5 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000008761 214.0
HFD1_k127_7986505_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000001023 111.0
HFD1_k127_7986505_7 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000001493 108.0
HFD1_k127_82838_0 Protein of unknown function, DUF255 K06888 - - 1.608e-237 753.0
HFD1_k127_82838_1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 1.364e-202 644.0
HFD1_k127_82838_10 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000003642 198.0
HFD1_k127_82838_11 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000001035 169.0
HFD1_k127_82838_12 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000002895 52.0
HFD1_k127_82838_2 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 481.0
HFD1_k127_82838_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 438.0
HFD1_k127_82838_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 430.0
HFD1_k127_82838_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 385.0
HFD1_k127_82838_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000075 241.0
HFD1_k127_82838_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000001097 249.0
HFD1_k127_82838_8 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000002518 209.0
HFD1_k127_82838_9 response regulator receiver K02483,K07658 - - 0.000000000000000000000000000000000000000000000000000001315 200.0
HFD1_k127_83201_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 345.0
HFD1_k127_83201_1 response regulator K07685 - - 0.0000000000000000000000000000000000000000000001277 175.0
HFD1_k127_83201_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000405 166.0
HFD1_k127_83201_3 - - - - 0.000000000001458 75.0
HFD1_k127_83990_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 8.798e-313 986.0
HFD1_k127_83990_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 6.524e-231 724.0
HFD1_k127_83990_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000412 230.0
HFD1_k127_83990_11 Protein tyrosine kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000007802 246.0
HFD1_k127_83990_12 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000001512 235.0
HFD1_k127_83990_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000001813 204.0
HFD1_k127_83990_14 RNA recognition motif - - - 0.000000000000000000000000000000000009812 141.0
HFD1_k127_83990_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000003397 129.0
HFD1_k127_83990_16 nuclear chromosome segregation - - - 0.0000000000000000000000003306 119.0
HFD1_k127_83990_17 Regulatory protein, FmdB - - - 0.0000000000000000000344 93.0
HFD1_k127_83990_18 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000001655 66.0
HFD1_k127_83990_19 general stress protein - - - 0.0000004926 57.0
HFD1_k127_83990_2 PFAM aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 540.0
HFD1_k127_83990_20 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.00004975 54.0
HFD1_k127_83990_3 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 487.0
HFD1_k127_83990_4 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 491.0
HFD1_k127_83990_5 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 463.0
HFD1_k127_83990_6 ATPases associated with a variety of cellular activities K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 330.0
HFD1_k127_83990_7 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 331.0
HFD1_k127_83990_8 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002163 290.0
HFD1_k127_83990_9 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003745 278.0
HFD1_k127_863250_0 Peptidase family M49 - - - 2.608e-211 670.0
HFD1_k127_863250_1 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 562.0
HFD1_k127_863250_10 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 295.0
HFD1_k127_863250_11 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007938 282.0
HFD1_k127_863250_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000007185 269.0
HFD1_k127_863250_13 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000001523 204.0
HFD1_k127_863250_14 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000002956 203.0
HFD1_k127_863250_15 UPF0314 protein - - - 0.0000000000000000000000000000000000005209 146.0
HFD1_k127_863250_16 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000444 134.0
HFD1_k127_863250_17 deoxyhypusine monooxygenase activity K05385 - - 0.00000000000000000000000001055 123.0
HFD1_k127_863250_18 HEAT repeats - - - 0.000000000000000000001013 108.0
HFD1_k127_863250_19 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000001443 108.0
HFD1_k127_863250_2 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 478.0
HFD1_k127_863250_20 Thioredoxin-like - - - 0.000000000000000000004677 106.0
HFD1_k127_863250_21 Recombinase - - - 0.000000000000000001298 88.0
HFD1_k127_863250_22 repeat protein - - - 0.0000000000003817 71.0
HFD1_k127_863250_23 oxidoreductase activity K12511 - - 0.000000000001271 80.0
HFD1_k127_863250_24 TPM domain K06872 - - 0.000000005095 70.0
HFD1_k127_863250_25 Glutathione peroxidase - - - 0.0000007013 59.0
HFD1_k127_863250_26 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000009532 63.0
HFD1_k127_863250_27 Recombinase zinc beta ribbon domain - - - 0.00004649 48.0
HFD1_k127_863250_28 sigma54 specific, transcriptional regulator, Fis family - - - 0.0002075 48.0
HFD1_k127_863250_3 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 455.0
HFD1_k127_863250_4 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 451.0
HFD1_k127_863250_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 451.0
HFD1_k127_863250_6 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 447.0
HFD1_k127_863250_7 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 431.0
HFD1_k127_863250_8 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 371.0
HFD1_k127_863250_9 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HFD1_k127_868820_0 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 355.0
HFD1_k127_868820_1 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 314.0
HFD1_k127_868820_2 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007948 274.0
HFD1_k127_868820_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000008725 242.0
HFD1_k127_868820_4 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.000000000000000000000000000000005637 132.0
HFD1_k127_868820_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000001497 127.0
HFD1_k127_868820_6 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.000000000001981 78.0
HFD1_k127_879641_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004474 258.0
HFD1_k127_879641_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000001476 176.0
HFD1_k127_883546_0 Phage tail protein (Tail_P2_I) - - - 2.05e-259 832.0
HFD1_k127_883546_1 Baseplate J-like protein - - - 2.449e-257 814.0
HFD1_k127_883546_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 344.0
HFD1_k127_883546_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 323.0
HFD1_k127_883546_4 GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000001911 167.0
HFD1_k127_883546_6 - - - - 0.000000004107 57.0
HFD1_k127_919819_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 642.0
HFD1_k127_919819_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 426.0
HFD1_k127_919819_2 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000001379 203.0
HFD1_k127_919819_3 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000008969 199.0
HFD1_k127_919819_4 - - - - 0.0000000000000000000000000000000000000000006097 159.0
HFD1_k127_919819_5 4-Hydroxyphenylpyruvate dioxygenase - - - 0.00000000000001152 74.0
HFD1_k127_919819_6 SMART Tetratricopeptide domain protein - - - 0.00009279 54.0
HFD1_k127_921451_0 PFAM ABC transporter related K06020 - 3.6.3.25 1.685e-306 945.0
HFD1_k127_921451_1 CarboxypepD_reg-like domain - - - 1.186e-235 774.0
HFD1_k127_921451_10 - - - - 0.000003068 51.0
HFD1_k127_921451_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 419.0
HFD1_k127_921451_3 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 407.0
HFD1_k127_921451_4 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 358.0
HFD1_k127_921451_5 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 308.0
HFD1_k127_921451_6 SEC-C domain protein K09858 - - 0.000000000000000000000000000000000000000000001425 169.0
HFD1_k127_921451_7 transcriptional regulator - - - 0.000000000000000000000000000000000003216 149.0
HFD1_k127_921451_8 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000009225 109.0
HFD1_k127_921451_9 Putative phosphatase (DUF442) - - - 0.000000000000000007911 94.0
HFD1_k127_92764_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 391.0
HFD1_k127_92764_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 332.0
HFD1_k127_92764_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 309.0
HFD1_k127_92764_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000001394 239.0
HFD1_k127_92764_4 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000002914 216.0
HFD1_k127_92764_5 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000001391 187.0
HFD1_k127_92764_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000001141 133.0
HFD1_k127_92764_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000006229 113.0
HFD1_k127_92764_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000002622 102.0
HFD1_k127_92764_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000003844 84.0
HFD1_k127_92833_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 377.0
HFD1_k127_92833_1 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 287.0
HFD1_k127_92833_2 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000005954 257.0
HFD1_k127_92833_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000002782 168.0
HFD1_k127_952683_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.647e-218 689.0
HFD1_k127_952683_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000007492 207.0
HFD1_k127_952683_2 Phosphotriesterase K07048 - - 0.000000000000000000000001561 102.0
HFD1_k127_965475_0 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 399.0
HFD1_k127_965475_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 374.0
HFD1_k127_965475_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004044 280.0
HFD1_k127_965475_3 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000006938 177.0
HFD1_k127_965475_4 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000001514 105.0
HFD1_k127_965475_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000008685 85.0
HFD1_k127_973157_0 Cytochrome c - - - 0.0 1242.0
HFD1_k127_973157_1 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 586.0
HFD1_k127_973157_2 iron assimilation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 571.0
HFD1_k127_973157_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 467.0
HFD1_k127_973157_4 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 408.0
HFD1_k127_973157_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000003947 194.0
HFD1_k127_973157_6 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.00000000000000000000000000009719 126.0
HFD1_k127_973157_7 membrane - - - 0.0005209 50.0
HFD1_k127_973157_8 Transglycosylase SLT domain - - - 0.0008485 51.0
HFD1_k127_979289_0 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 355.0
HFD1_k127_979289_1 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
HFD1_k127_979289_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000001286 241.0
HFD1_k127_979289_3 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000005516 199.0
HFD1_k127_979289_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000002932 112.0
HFD1_k127_979289_5 of the alpha beta superfamily K06889 - - 0.0001917 53.0
HFD1_k127_99179_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 485.0
HFD1_k127_99179_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 473.0
HFD1_k127_99179_10 radical SAM domain protein - - - 0.00000000003788 67.0
HFD1_k127_99179_2 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 310.0
HFD1_k127_99179_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000006502 262.0
HFD1_k127_99179_4 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007857 224.0
HFD1_k127_99179_5 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000006533 232.0
HFD1_k127_99179_6 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000005956 152.0
HFD1_k127_99179_7 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000634 146.0
HFD1_k127_99179_8 flavoprotein involved in K transport K07222 - - 0.00000000000000000000000006052 121.0
HFD1_k127_99179_9 Protein of unknown function (DUF4231) - - - 0.00000000000000000002538 102.0