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Overview

ID MAG01622
Name HFD1_bin.32
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class JACRHJ01
Order JACRHJ01
Family JACRHJ01
Genus
Species
Assembly information
Completeness (%) 97.44
Contamination (%) 1.88
GC content (%) 60.0
N50 (bp) 24,087
Genome size (bp) 2,632,450

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2434

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1016313_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.061e-273 860.0
HFD1_k127_1016313_1 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 529.0
HFD1_k127_1016313_2 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 493.0
HFD1_k127_1016313_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 436.0
HFD1_k127_1016313_4 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 415.0
HFD1_k127_1016313_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000007573 257.0
HFD1_k127_1016313_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000002008 170.0
HFD1_k127_1016313_7 - - - - 0.00000000000000000000007051 99.0
HFD1_k127_1016313_8 - - - - 0.00001168 51.0
HFD1_k127_1016313_9 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00005222 55.0
HFD1_k127_1018221_0 Alanine dehydrogenase/PNT, C-terminal domain K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 548.0
HFD1_k127_1018221_1 membrane protein involved in D-alanine export K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 532.0
HFD1_k127_1018221_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 490.0
HFD1_k127_1018221_3 helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 454.0
HFD1_k127_1018221_4 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 302.0
HFD1_k127_1018221_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006884 280.0
HFD1_k127_1018221_6 Belongs to the universal stress protein A family - - - 0.0000000000116 69.0
HFD1_k127_1031923_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 543.0
HFD1_k127_1031923_1 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000002041 218.0
HFD1_k127_1031923_2 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000008033 195.0
HFD1_k127_1031923_3 (SAM)-dependent - - - 0.00000000000000000000007094 100.0
HFD1_k127_1031923_4 TadE-like protein - - - 0.0000002249 59.0
HFD1_k127_1031923_5 PFAM TadE family protein - - - 0.0000004286 57.0
HFD1_k127_1066539_0 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 348.0
HFD1_k127_1066539_1 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003374 275.0
HFD1_k127_1066539_2 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009635 282.0
HFD1_k127_1066539_3 transferase activity, transferring glycosyl groups K02844 - - 0.0000000000000000000000000000000000000000000000000000000000001334 228.0
HFD1_k127_1066539_4 Sulfotransferase - - - 0.00000000000000000000000000000000000000000000000000000000002047 216.0
HFD1_k127_1066539_5 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000002499 214.0
HFD1_k127_1066539_6 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000001431 179.0
HFD1_k127_108104_0 TIGRFAM Ammonium transporter K03320 - - 6.911e-251 784.0
HFD1_k127_108104_1 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 593.0
HFD1_k127_108104_10 peptidase U32 - - - 0.0000000000000000000000000000000003393 143.0
HFD1_k127_108104_11 Type II secretory pathway, pseudopilin - - - 0.000000000000000000000000000000002003 141.0
HFD1_k127_108104_12 Protein of unknown function (DUF1573) - - - 0.0000000000000000000001871 106.0
HFD1_k127_108104_13 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000002262 90.0
HFD1_k127_108104_15 WD domain- G-beta repeat PBS lyase HEAT-like K03497 - - 0.000000000000001834 93.0
HFD1_k127_108104_16 Protein of unknown function (DUF1573) - - - 0.00000000000005117 83.0
HFD1_k127_108104_17 alginic acid biosynthetic process - - - 0.000000005445 68.0
HFD1_k127_108104_18 PBS lyase HEAT domain protein repeat-containing protein K22221 - - 0.00000002506 66.0
HFD1_k127_108104_2 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 364.0
HFD1_k127_108104_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 323.0
HFD1_k127_108104_4 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000008658 239.0
HFD1_k127_108104_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000006674 221.0
HFD1_k127_108104_6 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.000000000000000000000000000000000000000000000000000002327 200.0
HFD1_k127_108104_7 Predicted permease - - - 0.0000000000000000000000000000000000000000000000005253 186.0
HFD1_k127_108104_8 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000001352 175.0
HFD1_k127_108104_9 Pfam:N_methyl_2 K02456 - - 0.000000000000000000000000000000000000001051 151.0
HFD1_k127_1084638_0 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 610.0
HFD1_k127_1084638_1 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 487.0
HFD1_k127_1084638_2 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 379.0
HFD1_k127_1084638_3 reductase, beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000008443 231.0
HFD1_k127_1084638_4 reductase, alpha subunit K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000001579 203.0
HFD1_k127_1084638_5 denitrification pathway - - - 0.0000000009765 68.0
HFD1_k127_108834_0 4 iron, 4 sulfur cluster binding - - - 0.0 1435.0
HFD1_k127_108834_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 523.0
HFD1_k127_108834_10 Thiamine-binding protein - - - 0.000000000000000000000000000000003239 131.0
HFD1_k127_108834_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 475.0
HFD1_k127_108834_3 Hydrogenase expression formation protein (HypE) K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 336.0
HFD1_k127_108834_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 296.0
HFD1_k127_108834_5 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001019 267.0
HFD1_k127_108834_6 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000001667 199.0
HFD1_k127_108834_7 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000001346 196.0
HFD1_k127_108834_8 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.000000000000000000000000000000000000000000000000001465 210.0
HFD1_k127_108834_9 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000003941 154.0
HFD1_k127_1093896_0 response regulator K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 527.0
HFD1_k127_1093896_1 PAS domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 413.0
HFD1_k127_1093896_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 394.0
HFD1_k127_1093896_3 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 365.0
HFD1_k127_1093896_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000004612 124.0
HFD1_k127_1093896_5 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000002949 107.0
HFD1_k127_1093896_6 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000001892 65.0
HFD1_k127_1134931_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1273.0
HFD1_k127_1134931_1 Aminotransferase class I and II K14261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 600.0
HFD1_k127_1134931_10 Domain of unknown function (DUF4911) - - - 0.0001017 52.0
HFD1_k127_1134931_2 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 556.0
HFD1_k127_1134931_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 535.0
HFD1_k127_1134931_4 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 530.0
HFD1_k127_1134931_5 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 507.0
HFD1_k127_1134931_6 Proposed homoserine kinase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 480.0
HFD1_k127_1134931_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 411.0
HFD1_k127_1134931_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 349.0
HFD1_k127_1134931_9 nuclease - - - 0.000008758 48.0
HFD1_k127_1141895_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 564.0
HFD1_k127_1141895_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 555.0
HFD1_k127_1141895_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000001904 226.0
HFD1_k127_1141895_11 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000003706 178.0
HFD1_k127_1141895_12 - - - - 0.000000000000001017 84.0
HFD1_k127_1141895_13 - - - - 0.000002998 49.0
HFD1_k127_1141895_2 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 443.0
HFD1_k127_1141895_3 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 375.0
HFD1_k127_1141895_4 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 345.0
HFD1_k127_1141895_5 Major facilitator Superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 315.0
HFD1_k127_1141895_6 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000165 275.0
HFD1_k127_1141895_7 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004511 252.0
HFD1_k127_1141895_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000485 228.0
HFD1_k127_1141895_9 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000007929 237.0
HFD1_k127_1164767_0 Domains REC, sigma54 interaction, HTH8 K02481 - - 5.845e-196 622.0
HFD1_k127_1164767_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 575.0
HFD1_k127_1164767_10 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 345.0
HFD1_k127_1164767_11 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 335.0
HFD1_k127_1164767_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 323.0
HFD1_k127_1164767_13 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 314.0
HFD1_k127_1164767_14 TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 297.0
HFD1_k127_1164767_15 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008702 282.0
HFD1_k127_1164767_16 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003551 244.0
HFD1_k127_1164767_17 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000823 243.0
HFD1_k127_1164767_18 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001019 228.0
HFD1_k127_1164767_19 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000001707 230.0
HFD1_k127_1164767_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 521.0
HFD1_k127_1164767_20 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000001802 211.0
HFD1_k127_1164767_21 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000002524 199.0
HFD1_k127_1164767_22 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000001488 191.0
HFD1_k127_1164767_23 - - - - 0.0000000000000000000000000000000000000000007373 170.0
HFD1_k127_1164767_24 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000001984 147.0
HFD1_k127_1164767_25 eight transmembrane protein EpsH - - - 0.000000000000000000000000000000003264 143.0
HFD1_k127_1164767_26 TIGRFAM FemAB-related protein, PEP-CTERM - - - 0.000000000000000000000000001283 127.0
HFD1_k127_1164767_28 Polysaccharide deacetylase - - - 0.0000000000000001295 92.0
HFD1_k127_1164767_29 - - - - 0.000000004675 66.0
HFD1_k127_1164767_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 514.0
HFD1_k127_1164767_30 - - - - 0.00001157 58.0
HFD1_k127_1164767_31 Acetyltransferase (GNAT) family - - - 0.0002536 51.0
HFD1_k127_1164767_32 LmbE family - - - 0.0007031 47.0
HFD1_k127_1164767_4 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 461.0
HFD1_k127_1164767_5 UDP-N-acetylglucosamine 2-epimerase K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 460.0
HFD1_k127_1164767_6 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 403.0
HFD1_k127_1164767_7 Undecaprenyl-phosphate galactose phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 366.0
HFD1_k127_1164767_8 Glycosyl transferase K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 356.0
HFD1_k127_1164767_9 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 349.0
HFD1_k127_1175054_0 Glycosyl hydrolase family 57 - - - 6.521e-205 660.0
HFD1_k127_1175054_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.339e-199 628.0
HFD1_k127_1175054_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 569.0
HFD1_k127_1175054_3 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 493.0
HFD1_k127_1175054_4 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 364.0
HFD1_k127_1175054_5 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004242 257.0
HFD1_k127_1175054_6 RNA recognition motif - - - 0.0000000000000000000000000000387 119.0
HFD1_k127_1175054_7 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.0000001973 57.0
HFD1_k127_1292844_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 447.0
HFD1_k127_1292844_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008996 285.0
HFD1_k127_1292844_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
HFD1_k127_1292844_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006851 226.0
HFD1_k127_1292844_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000002287 224.0
HFD1_k127_1292844_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000003298 205.0
HFD1_k127_1292844_6 Methyltransferase type 11 - - - 0.00000000000001958 82.0
HFD1_k127_1296729_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 563.0
HFD1_k127_1296729_1 Histidine kinase K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003288 276.0
HFD1_k127_1296729_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000006862 219.0
HFD1_k127_1296729_3 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000000000000000000002273 165.0
HFD1_k127_1296729_4 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000001232 149.0
HFD1_k127_1296729_5 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000001683 164.0
HFD1_k127_1296729_6 Domain of unknown function (DUF378) K09779 - - 0.000000000007308 68.0
HFD1_k127_1296729_7 Amylo-alpha-1,6-glucosidase - - - 0.00004721 57.0
HFD1_k127_1323635_0 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 465.0
HFD1_k127_1323635_1 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
HFD1_k127_1323635_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000359 270.0
HFD1_k127_1323635_3 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004314 269.0
HFD1_k127_1398447_0 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 377.0
HFD1_k127_1398447_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 348.0
HFD1_k127_1398447_10 Phosphate-selective porin O and P - - - 0.00000000000000008308 94.0
HFD1_k127_1398447_11 Outer membrane lipoprotein - - - 0.000000000000006059 85.0
HFD1_k127_1398447_13 Belongs to the Smg family K03747 - - 0.00009892 51.0
HFD1_k127_1398447_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 296.0
HFD1_k127_1398447_3 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001521 251.0
HFD1_k127_1398447_4 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000007717 231.0
HFD1_k127_1398447_5 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000004781 214.0
HFD1_k127_1398447_6 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000001432 199.0
HFD1_k127_1398447_7 phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000001486 157.0
HFD1_k127_1398447_8 Lysin motif - - - 0.00000000000000000000000000000002111 140.0
HFD1_k127_1398447_9 - - - - 0.00000000000000005435 86.0
HFD1_k127_1411320_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 527.0
HFD1_k127_1411320_1 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 424.0
HFD1_k127_1411320_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000002268 137.0
HFD1_k127_1411320_11 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000002213 124.0
HFD1_k127_1411320_13 Domain of unknown function (DUF4418) - - - 0.000000009261 61.0
HFD1_k127_1411320_14 amine dehydrogenase activity - - - 0.000003128 59.0
HFD1_k127_1411320_15 Protein of unknown function (DUF3343) - - - 0.000004904 51.0
HFD1_k127_1411320_16 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0001824 54.0
HFD1_k127_1411320_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 368.0
HFD1_k127_1411320_3 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 349.0
HFD1_k127_1411320_4 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000002141 250.0
HFD1_k127_1411320_5 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000000000000000000000000000000000000000000000001093 231.0
HFD1_k127_1411320_6 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000002103 207.0
HFD1_k127_1411320_7 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000002385 205.0
HFD1_k127_1411320_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000005923 188.0
HFD1_k127_1411320_9 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000000000000000000217 151.0
HFD1_k127_1445273_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 474.0
HFD1_k127_1445273_1 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 459.0
HFD1_k127_1445273_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 376.0
HFD1_k127_1445273_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000009946 222.0
HFD1_k127_1445273_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000001144 79.0
HFD1_k127_1445273_5 Alpha beta - - - 0.000000000000003461 85.0
HFD1_k127_151321_0 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000004187 243.0
HFD1_k127_151321_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000462 233.0
HFD1_k127_151321_2 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000009406 106.0
HFD1_k127_1588592_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1107.0
HFD1_k127_1588592_1 Heat shock 70 kDa protein K04043 - - 6.368e-306 948.0
HFD1_k127_1588592_10 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 366.0
HFD1_k127_1588592_11 integrase domain protein SAM domain protein K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 348.0
HFD1_k127_1588592_12 HrcA protein C terminal domain K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 317.0
HFD1_k127_1588592_13 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007009 277.0
HFD1_k127_1588592_14 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004963 289.0
HFD1_k127_1588592_15 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003823 260.0
HFD1_k127_1588592_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009673 252.0
HFD1_k127_1588592_17 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000002435 251.0
HFD1_k127_1588592_18 Fibronectin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005516 261.0
HFD1_k127_1588592_19 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004206 238.0
HFD1_k127_1588592_2 CBS domain containing protein K00974 - 2.7.7.72 2.628e-276 876.0
HFD1_k127_1588592_20 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000003247 234.0
HFD1_k127_1588592_21 hopanoid biosynthesis associated protein HpnK - - - 0.000000000000000000000000000000000000000000000000000000000003642 218.0
HFD1_k127_1588592_22 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002489 208.0
HFD1_k127_1588592_23 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000007536 212.0
HFD1_k127_1588592_24 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000001167 207.0
HFD1_k127_1588592_25 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000007749 204.0
HFD1_k127_1588592_26 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000002682 203.0
HFD1_k127_1588592_27 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000001258 194.0
HFD1_k127_1588592_28 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000002634 192.0
HFD1_k127_1588592_29 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000000000193 176.0
HFD1_k127_1588592_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.748e-220 704.0
HFD1_k127_1588592_30 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000001302 171.0
HFD1_k127_1588592_31 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000000000001071 151.0
HFD1_k127_1588592_32 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000006651 139.0
HFD1_k127_1588592_33 Thioesterase superfamily K03186 - 2.5.1.129 0.0000000000000000000000000000000002573 136.0
HFD1_k127_1588592_34 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000003342 133.0
HFD1_k127_1588592_36 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000004418 95.0
HFD1_k127_1588592_37 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000006541 92.0
HFD1_k127_1588592_38 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000001333 98.0
HFD1_k127_1588592_39 - - - - 0.000003882 58.0
HFD1_k127_1588592_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 476.0
HFD1_k127_1588592_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 449.0
HFD1_k127_1588592_6 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 436.0
HFD1_k127_1588592_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 411.0
HFD1_k127_1588592_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 402.0
HFD1_k127_1588592_9 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 385.0
HFD1_k127_1614133_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 509.0
HFD1_k127_1614133_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 439.0
HFD1_k127_1614133_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 421.0
HFD1_k127_1614133_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000002733 237.0
HFD1_k127_1614133_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
HFD1_k127_1614133_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000001638 139.0
HFD1_k127_1614133_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000005569 136.0
HFD1_k127_1614696_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 613.0
HFD1_k127_1614696_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 416.0
HFD1_k127_1614696_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001429 197.0
HFD1_k127_1614696_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000207 197.0
HFD1_k127_1614696_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000365 195.0
HFD1_k127_1614696_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000002119 184.0
HFD1_k127_1614696_14 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000001132 183.0
HFD1_k127_1614696_15 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001814 168.0
HFD1_k127_1614696_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000611 156.0
HFD1_k127_1614696_17 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000002493 155.0
HFD1_k127_1614696_18 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000001532 135.0
HFD1_k127_1614696_19 - - - - 0.0000000000000000000000000000000001996 136.0
HFD1_k127_1614696_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 336.0
HFD1_k127_1614696_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000009858 114.0
HFD1_k127_1614696_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001016 109.0
HFD1_k127_1614696_22 cation diffusion facilitator family transporter - - - 0.0000000000000000000000005995 109.0
HFD1_k127_1614696_23 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000004715 90.0
HFD1_k127_1614696_24 Ribosomal protein L30p/L7e K02907 - - 0.000000000000005079 76.0
HFD1_k127_1614696_25 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001321 70.0
HFD1_k127_1614696_26 rubredoxin - - - 0.000000000000149 72.0
HFD1_k127_1614696_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
HFD1_k127_1614696_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 291.0
HFD1_k127_1614696_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006317 275.0
HFD1_k127_1614696_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001004 223.0
HFD1_k127_1614696_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002573 224.0
HFD1_k127_1614696_8 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000000000000006517 213.0
HFD1_k127_1614696_9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002081 204.0
HFD1_k127_163149_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 441.0
HFD1_k127_163149_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 419.0
HFD1_k127_163149_2 Thiamine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002196 286.0
HFD1_k127_163149_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K20810 - 3.5.4.40 0.000000000000000000000000000000001297 134.0
HFD1_k127_163149_4 Dodecin K09165 - - 0.000000000000001295 78.0
HFD1_k127_1672093_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 402.0
HFD1_k127_1672093_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 387.0
HFD1_k127_1672093_10 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000001401 111.0
HFD1_k127_1672093_12 Bacterial protein of unknown function (Gcw_chp) - - - 0.0002529 53.0
HFD1_k127_1672093_2 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 321.0
HFD1_k127_1672093_3 transmembrane transporter activity K02007,K02008 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 327.0
HFD1_k127_1672093_4 Cytochrome b/b6/petB K03887 - - 0.000000000000000000000000000000000000000000000000000000000000000000005213 242.0
HFD1_k127_1672093_5 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000005004 228.0
HFD1_k127_1672093_6 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000000000001088 218.0
HFD1_k127_1672093_7 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000003142 212.0
HFD1_k127_1672093_8 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000002585 201.0
HFD1_k127_1672093_9 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000001033 183.0
HFD1_k127_1702157_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 1.606e-259 835.0
HFD1_k127_1702157_1 Cytochrome c3 - - - 3.777e-244 790.0
HFD1_k127_1702157_10 6 heme-binding sites - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 303.0
HFD1_k127_1702157_11 6 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 298.0
HFD1_k127_1702157_12 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003129 261.0
HFD1_k127_1702157_13 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005303 265.0
HFD1_k127_1702157_14 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006752 260.0
HFD1_k127_1702157_15 Putative bacterial lipoprotein (DUF799) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001395 241.0
HFD1_k127_1702157_16 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000001539 207.0
HFD1_k127_1702157_17 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000002321 162.0
HFD1_k127_1702157_18 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000001321 155.0
HFD1_k127_1702157_19 Protein of unknown function (DUF1722) - - - 0.00000000000000000000002082 100.0
HFD1_k127_1702157_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 590.0
HFD1_k127_1702157_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 514.0
HFD1_k127_1702157_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 520.0
HFD1_k127_1702157_5 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 414.0
HFD1_k127_1702157_6 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 405.0
HFD1_k127_1702157_7 6 heme-binding sites - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 389.0
HFD1_k127_1702157_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 388.0
HFD1_k127_1702157_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 300.0
HFD1_k127_1715540_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000001262 198.0
HFD1_k127_1715540_1 Tetratricopeptide repeat - - - 0.000002056 53.0
HFD1_k127_1731857_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 534.0
HFD1_k127_1731857_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 346.0
HFD1_k127_1731857_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000002331 235.0
HFD1_k127_1731857_11 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000005203 186.0
HFD1_k127_1731857_12 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000002203 138.0
HFD1_k127_1731857_13 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000007851 95.0
HFD1_k127_1731857_14 Domain of unknown function (DUF374) K09778 - - 0.00000002922 62.0
HFD1_k127_1731857_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 332.0
HFD1_k127_1731857_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 331.0
HFD1_k127_1731857_4 PFAM glycosyl transferase, family 9 K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001242 275.0
HFD1_k127_1731857_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003789 271.0
HFD1_k127_1731857_6 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000007439 267.0
HFD1_k127_1731857_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000005365 265.0
HFD1_k127_1731857_8 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004243 259.0
HFD1_k127_1731857_9 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007362 247.0
HFD1_k127_1797438_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 458.0
HFD1_k127_1797438_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003655 261.0
HFD1_k127_1797438_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000001187 169.0
HFD1_k127_1797438_3 EamA-like transporter family - - - 0.000000000000000000000000000005482 132.0
HFD1_k127_1797438_4 Psort location Extracellular, score - - - 0.00000000000000000000000000001688 132.0
HFD1_k127_1797438_5 KR domain - - - 0.00000000000000000000000000001921 127.0
HFD1_k127_18050_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1798.0
HFD1_k127_18050_1 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 3.732e-291 905.0
HFD1_k127_18050_10 Transcriptional regulator K18136 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003221 259.0
HFD1_k127_18050_11 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003744 256.0
HFD1_k127_18050_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000009784 247.0
HFD1_k127_18050_13 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000001525 243.0
HFD1_k127_18050_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004057 234.0
HFD1_k127_18050_15 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 - 0.0000000000000000000000000000000000000000000009064 186.0
HFD1_k127_18050_16 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000001296 108.0
HFD1_k127_18050_17 amine dehydrogenase activity K20276 - - 0.0000000000000000001216 104.0
HFD1_k127_18050_18 HicA toxin of bacterial toxin-antitoxin, K07339 - - 0.0000000000000000003346 90.0
HFD1_k127_18050_2 - - - - 7.723e-231 719.0
HFD1_k127_18050_20 AMP binding - - - 0.000000000001869 69.0
HFD1_k127_18050_21 - - - - 0.00000000001031 74.0
HFD1_k127_18050_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 1.898e-201 637.0
HFD1_k127_18050_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 522.0
HFD1_k127_18050_5 Phospholipase D Transphosphatidylase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 504.0
HFD1_k127_18050_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 501.0
HFD1_k127_18050_7 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 318.0
HFD1_k127_18050_8 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 327.0
HFD1_k127_18050_9 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009808 276.0
HFD1_k127_181950_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 526.0
HFD1_k127_181950_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 503.0
HFD1_k127_181950_10 TIGRFAM ribonuclease BN K07058 - - 0.000000000000004842 85.0
HFD1_k127_181950_11 - - - - 0.000000000003366 69.0
HFD1_k127_181950_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.00000002394 56.0
HFD1_k127_181950_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 479.0
HFD1_k127_181950_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 317.0
HFD1_k127_181950_4 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000001431 278.0
HFD1_k127_181950_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000007578 246.0
HFD1_k127_181950_6 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003298 259.0
HFD1_k127_181950_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000009716 236.0
HFD1_k127_181950_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000007523 181.0
HFD1_k127_181950_9 oxidoreductase K00334 - 1.6.5.3 0.000000000000000000000000000000000000000003355 159.0
HFD1_k127_1839995_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 533.0
HFD1_k127_1839995_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004869 255.0
HFD1_k127_1839995_2 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000005648 136.0
HFD1_k127_1875504_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1164.0
HFD1_k127_1875504_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 352.0
HFD1_k127_1875504_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 322.0
HFD1_k127_1875504_3 NADPH quinone reductase - - - 0.00000000000000000000000000000000004004 138.0
HFD1_k127_1875504_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000007252 97.0
HFD1_k127_1875504_5 - - - - 0.000000114 55.0
HFD1_k127_188747_0 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 1.203e-230 732.0
HFD1_k127_188747_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 1.285e-229 723.0
HFD1_k127_188747_10 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
HFD1_k127_188747_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000001383 269.0
HFD1_k127_188747_12 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000002331 207.0
HFD1_k127_188747_13 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000001538 185.0
HFD1_k127_188747_14 thiolester hydrolase activity K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000008442 178.0
HFD1_k127_188747_15 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000000000000000000000000000000007449 171.0
HFD1_k127_188747_16 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000003895 155.0
HFD1_k127_188747_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000003637 137.0
HFD1_k127_188747_18 - - - - 0.00000000000000000007308 96.0
HFD1_k127_188747_19 - - - - 0.00000000000000009872 84.0
HFD1_k127_188747_2 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 605.0
HFD1_k127_188747_20 - - - - 0.00000000000002566 80.0
HFD1_k127_188747_21 His Kinase A (phosphoacceptor) domain - - - 0.0000000000001149 83.0
HFD1_k127_188747_22 - - - - 0.0000000000003555 75.0
HFD1_k127_188747_23 Transcriptional regulatory protein, C terminal K07658 - - 0.000000005474 68.0
HFD1_k127_188747_24 P-type ATPase K17686 - 3.6.3.54 0.00000006804 55.0
HFD1_k127_188747_25 Belongs to the GbsR family K22109 - - 0.000006036 55.0
HFD1_k127_188747_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 514.0
HFD1_k127_188747_4 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 486.0
HFD1_k127_188747_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 420.0
HFD1_k127_188747_6 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 391.0
HFD1_k127_188747_7 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 374.0
HFD1_k127_188747_8 PFAM glutamate synthase alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 308.0
HFD1_k127_188747_9 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001735 288.0
HFD1_k127_1917043_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.965e-253 805.0
HFD1_k127_1917043_1 TonB dependent receptor K02014 - - 2.847e-247 781.0
HFD1_k127_1917043_10 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 313.0
HFD1_k127_1917043_11 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002862 273.0
HFD1_k127_1917043_12 Domain of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000001151 238.0
HFD1_k127_1917043_13 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000005267 205.0
HFD1_k127_1917043_14 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000001052 202.0
HFD1_k127_1917043_15 - - - - 0.0000000000000000000000000000000000000000000000002491 190.0
HFD1_k127_1917043_17 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000006338 177.0
HFD1_k127_1917043_18 Histidine kinase K07651 - 2.7.13.3 0.00000000000000000000000000000000000000000005155 182.0
HFD1_k127_1917043_19 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000001161 171.0
HFD1_k127_1917043_2 Protein involved in outer membrane biogenesis - - - 1.453e-244 797.0
HFD1_k127_1917043_20 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000001728 147.0
HFD1_k127_1917043_21 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000000008518 132.0
HFD1_k127_1917043_22 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000004947 130.0
HFD1_k127_1917043_23 Response regulator receiver domain - - - 0.0000000000000000000000000000004103 126.0
HFD1_k127_1917043_24 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.00000000000000000000000000000458 127.0
HFD1_k127_1917043_25 energy transducer activity K03646,K03832 - - 0.0000000000000000000000004088 115.0
HFD1_k127_1917043_26 copG family - - - 0.00000000000000000000002575 101.0
HFD1_k127_1917043_27 Cold-shock protein K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000001576 98.0
HFD1_k127_1917043_28 Helix-hairpin-helix motif - - - 0.000000000000000000002689 99.0
HFD1_k127_1917043_29 Predicted membrane protein (DUF2318) K09005 - - 0.00000000000000000005072 95.0
HFD1_k127_1917043_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 559.0
HFD1_k127_1917043_30 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000006258 92.0
HFD1_k127_1917043_31 Thioredoxin-like K03671 - - 0.0000000000000000001225 94.0
HFD1_k127_1917043_32 PilZ domain - - - 0.000000000004779 71.0
HFD1_k127_1917043_34 Polyketide cyclase / dehydrase and lipid transport K05554 - - 0.000706 49.0
HFD1_k127_1917043_4 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 526.0
HFD1_k127_1917043_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 462.0
HFD1_k127_1917043_6 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 422.0
HFD1_k127_1917043_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 389.0
HFD1_k127_1917043_8 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 370.0
HFD1_k127_1917043_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 317.0
HFD1_k127_2206402_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 442.0
HFD1_k127_2206402_1 GatB domain K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 363.0
HFD1_k127_2206402_2 denitrification pathway K02569,K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000002416 253.0
HFD1_k127_2206402_3 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005006 250.0
HFD1_k127_2206402_4 nitric oxide dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001009 253.0
HFD1_k127_2206402_5 amine dehydrogenase activity - - - 0.0000000000000000000000003737 121.0
HFD1_k127_2206402_7 regulatory protein, FmdB family - - - 0.000000000000000000005388 96.0
HFD1_k127_2239107_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 599.0
HFD1_k127_2239107_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 590.0
HFD1_k127_2239107_10 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000006581 158.0
HFD1_k127_2239107_11 PEP-CTERM motif - - - 0.00000000000000000000000000000000000001235 153.0
HFD1_k127_2239107_12 Fibronectin type 3 domain - - - 0.000000000000000000000000000002108 141.0
HFD1_k127_2239107_13 Transcription termination factor nusG - - - 0.000000000000000000000000004171 114.0
HFD1_k127_2239107_14 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000002267 120.0
HFD1_k127_2239107_15 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000001609 121.0
HFD1_k127_2239107_16 Domain of unknown function (DUF4082) - - - 0.0000000000002252 85.0
HFD1_k127_2239107_17 Mo-co oxidoreductase dimerisation domain - - - 0.0000003775 64.0
HFD1_k127_2239107_18 Bacterial Ig-like domain - - - 0.00000342 61.0
HFD1_k127_2239107_19 - - - - 0.00008313 52.0
HFD1_k127_2239107_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 549.0
HFD1_k127_2239107_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 565.0
HFD1_k127_2239107_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 490.0
HFD1_k127_2239107_5 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 438.0
HFD1_k127_2239107_6 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 427.0
HFD1_k127_2239107_7 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 329.0
HFD1_k127_2239107_8 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001396 225.0
HFD1_k127_2239107_9 PFAM Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000001508 200.0
HFD1_k127_2246209_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 469.0
HFD1_k127_2246209_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 369.0
HFD1_k127_2246209_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006261 285.0
HFD1_k127_2262548_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 304.0
HFD1_k127_2262548_1 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000008015 170.0
HFD1_k127_2262548_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000002448 137.0
HFD1_k127_2262548_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000006275 128.0
HFD1_k127_2262548_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000989 118.0
HFD1_k127_2262548_5 Sporulation and spore germination - - - 0.00000000000000000000000000105 123.0
HFD1_k127_2262548_6 Ami_3 K01448 - 3.5.1.28 0.000000000000000000002691 106.0
HFD1_k127_2262548_7 periplasmic or secreted lipoprotein - - - 0.00000000000000006554 81.0
HFD1_k127_2262548_8 Flavin reductase like domain - - - 0.00000000000002292 72.0
HFD1_k127_228935_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1379.0
HFD1_k127_228935_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 3.145e-319 1000.0
HFD1_k127_228935_10 RmuC family K09760 - - 0.00000000000000000000000002375 111.0
HFD1_k127_228935_11 - - - - 0.00000000000000000000001427 113.0
HFD1_k127_228935_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
HFD1_k127_228935_3 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000009013 244.0
HFD1_k127_228935_4 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000000000000000000000000004457 218.0
HFD1_k127_228935_5 Conserved protein K01163 - - 0.0000000000000000000000000000000000000000000000000000000007885 213.0
HFD1_k127_228935_6 - - - - 0.00000000000000000000000000000000000000000000000000000002923 205.0
HFD1_k127_228935_7 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000163 144.0
HFD1_k127_228935_8 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000006598 129.0
HFD1_k127_228935_9 Transglycosylase associated protein - - - 0.000000000000000000000000000006397 120.0
HFD1_k127_2400138_0 amine oxidase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 398.0
HFD1_k127_2400138_1 Domain of unknown function (DUF1956) - - - 0.00000000000000000000000000000000000000000000000000000000000000003342 229.0
HFD1_k127_2400138_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000137 166.0
HFD1_k127_2400138_3 Amino acid permease - - - 0.00000000000000000000000000000000000000003118 155.0
HFD1_k127_2400138_4 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000002019 125.0
HFD1_k127_2476509_0 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000004388 190.0
HFD1_k127_2476509_1 Fe-S oxidoreductase - - - 0.00000000000000000005596 99.0
HFD1_k127_2476509_2 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000009973 51.0
HFD1_k127_2501704_0 PFAM magnesium chelatase ChlI subunit K07391 - - 1.595e-205 658.0
HFD1_k127_2501704_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 4.308e-204 647.0
HFD1_k127_2501704_10 histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009556 287.0
HFD1_k127_2501704_11 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000568 229.0
HFD1_k127_2501704_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001027 221.0
HFD1_k127_2501704_13 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000006194 193.0
HFD1_k127_2501704_14 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000006515 175.0
HFD1_k127_2501704_15 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000001214 179.0
HFD1_k127_2501704_16 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000007517 175.0
HFD1_k127_2501704_17 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000001842 174.0
HFD1_k127_2501704_18 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000003408 161.0
HFD1_k127_2501704_19 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000007229 128.0
HFD1_k127_2501704_2 PFAM CHASE2 domain - - - 4.788e-200 637.0
HFD1_k127_2501704_20 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000004622 126.0
HFD1_k127_2501704_22 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000001787 110.0
HFD1_k127_2501704_23 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000002202 87.0
HFD1_k127_2501704_24 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000004903 80.0
HFD1_k127_2501704_25 Domain of unknown function (DUF4082) - - - 0.000000000000002306 91.0
HFD1_k127_2501704_26 histone H2A K63-linked ubiquitination - - - 0.00000117 59.0
HFD1_k127_2501704_27 cell adhesion involved in biofilm formation - - - 0.00001496 58.0
HFD1_k127_2501704_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 519.0
HFD1_k127_2501704_4 RecF/RecN/SMC N terminal domain K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 414.0
HFD1_k127_2501704_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 386.0
HFD1_k127_2501704_6 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 402.0
HFD1_k127_2501704_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 362.0
HFD1_k127_2501704_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 354.0
HFD1_k127_2501704_9 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 334.0
HFD1_k127_2514368_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1518.0
HFD1_k127_2514368_1 PFAM Sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 313.0
HFD1_k127_2514368_2 - - - - 0.00000000006573 68.0
HFD1_k127_2514368_3 - - - - 0.0002209 47.0
HFD1_k127_261597_0 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 434.0
HFD1_k127_261597_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 402.0
HFD1_k127_261597_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000005593 141.0
HFD1_k127_2677077_0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 - 1.3.5.1,1.3.5.4 1.124e-267 834.0
HFD1_k127_2677077_1 Cache domain - - - 1.588e-195 619.0
HFD1_k127_2677077_2 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 427.0
HFD1_k127_2677077_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 411.0
HFD1_k127_2677077_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 385.0
HFD1_k127_2677077_5 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 321.0
HFD1_k127_2677077_6 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000135 167.0
HFD1_k127_2677077_7 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000001721 169.0
HFD1_k127_2677077_8 4Fe-4S binding domain - - - 0.000000000003955 68.0
HFD1_k127_2677077_9 - - - - 0.00000001334 62.0
HFD1_k127_2683975_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 9.851e-260 819.0
HFD1_k127_2683975_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 300.0
HFD1_k127_2683975_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000003772 189.0
HFD1_k127_2683975_3 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000001404 168.0
HFD1_k127_2683975_4 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000008426 168.0
HFD1_k127_2683975_5 - - - - 0.000004196 52.0
HFD1_k127_27379_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 319.0
HFD1_k127_27379_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006545 241.0
HFD1_k127_27379_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000004368 216.0
HFD1_k127_27379_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000003747 177.0
HFD1_k127_27379_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000001113 150.0
HFD1_k127_27379_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000001341 150.0
HFD1_k127_27379_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000002931 90.0
HFD1_k127_27379_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000389 53.0
HFD1_k127_2837191_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.049e-277 865.0
HFD1_k127_2837191_1 Domain of unknown function (DUF1957) K16149 - 2.4.1.18 9.407e-249 777.0
HFD1_k127_2837191_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 297.0
HFD1_k127_2837191_11 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 281.0
HFD1_k127_2837191_12 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001715 259.0
HFD1_k127_2837191_13 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001872 232.0
HFD1_k127_2837191_14 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000001181 196.0
HFD1_k127_2837191_15 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000003606 181.0
HFD1_k127_2837191_16 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000001886 187.0
HFD1_k127_2837191_17 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000007672 176.0
HFD1_k127_2837191_18 Domain of unknown function (DUF4912) K09942 - - 0.00000000000000000000000000000000000000000000008727 183.0
HFD1_k127_2837191_19 cyclic nucleotide binding K01420,K10716,K10914,K16922 - - 0.0000000000000000000000000000000000000000003313 166.0
HFD1_k127_2837191_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.65e-245 771.0
HFD1_k127_2837191_20 YbbR-like protein - - - 0.000000000000000000000000000000003617 136.0
HFD1_k127_2837191_21 isomerase activity K01821 - 5.3.2.6 0.0000000000000000000000000003467 115.0
HFD1_k127_2837191_22 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000007456 121.0
HFD1_k127_2837191_23 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000008672 105.0
HFD1_k127_2837191_24 - - - - 0.0000000000000000006558 88.0
HFD1_k127_2837191_25 - - - - 0.0000000000001637 74.0
HFD1_k127_2837191_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 1.723e-234 733.0
HFD1_k127_2837191_4 transporter antisigma-factor antagonist STAS K03321 - - 1.462e-227 719.0
HFD1_k127_2837191_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.967e-196 620.0
HFD1_k127_2837191_6 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 332.0
HFD1_k127_2837191_8 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 305.0
HFD1_k127_2837191_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 287.0
HFD1_k127_2914838_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K00533 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 591.0
HFD1_k127_2914838_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 390.0
HFD1_k127_2914838_10 - - - - 0.0000000000001234 73.0
HFD1_k127_2914838_11 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.00000000002475 65.0
HFD1_k127_2914838_2 Hydrogenase (NiFe) small subunit HydA K05927,K06282,K18008 - 1.12.2.1,1.12.5.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 309.0
HFD1_k127_2914838_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00595 - 2.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 308.0
HFD1_k127_2914838_4 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 294.0
HFD1_k127_2914838_5 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 295.0
HFD1_k127_2914838_6 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000002591 153.0
HFD1_k127_2914838_7 Prokaryotic cytochrome b561 K03620 - - 0.00000000000000000000000003994 116.0
HFD1_k127_2914838_8 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000001316 110.0
HFD1_k127_2914838_9 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000005846 79.0
HFD1_k127_295706_0 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 603.0
HFD1_k127_295706_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 563.0
HFD1_k127_295706_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000001714 192.0
HFD1_k127_295706_11 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000007421 194.0
HFD1_k127_295706_12 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000001616 179.0
HFD1_k127_295706_13 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000001596 178.0
HFD1_k127_295706_14 Flavin containing amine oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000000000000000009104 109.0
HFD1_k127_295706_15 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000002895 91.0
HFD1_k127_295706_16 Domain of unknown function (DUF4410) - - - 0.00000000000000002236 89.0
HFD1_k127_295706_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 439.0
HFD1_k127_295706_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 381.0
HFD1_k127_295706_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 350.0
HFD1_k127_295706_5 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 327.0
HFD1_k127_295706_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 306.0
HFD1_k127_295706_7 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 303.0
HFD1_k127_295706_8 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001237 292.0
HFD1_k127_295706_9 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 249.0
HFD1_k127_3119901_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1075.0
HFD1_k127_3119901_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.673e-284 899.0
HFD1_k127_3119901_10 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000008102 203.0
HFD1_k127_3119901_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000009692 208.0
HFD1_k127_3119901_12 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000002971 184.0
HFD1_k127_3119901_13 GAF domain - - - 0.00000000000000000000000000000000000000000000000009186 192.0
HFD1_k127_3119901_14 symporter activity K03307 - - 0.000000000000000000000000000000000000002411 153.0
HFD1_k127_3119901_15 Histidine kinase - - - 0.00000000000000000000000000000000000001072 156.0
HFD1_k127_3119901_16 Chromate transporter K07240 - - 0.000000000000000000000000000000007169 134.0
HFD1_k127_3119901_17 12 heme-binding sites - - - 0.0000000000000000000000000000002911 128.0
HFD1_k127_3119901_18 PFAM Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000004643 124.0
HFD1_k127_3119901_19 Chromate transport protein K07240 - - 0.000000000000000000000000000004139 127.0
HFD1_k127_3119901_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 387.0
HFD1_k127_3119901_20 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000001412 113.0
HFD1_k127_3119901_21 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000561 104.0
HFD1_k127_3119901_22 Tetratricopeptide repeat - - - 0.000000000000000000007073 102.0
HFD1_k127_3119901_23 Universal stress protein - - - 0.000000000000000000008264 103.0
HFD1_k127_3119901_24 methyltransferase activity - - - 0.0000000000000000003601 96.0
HFD1_k127_3119901_25 - - - - 0.00000000000000001685 87.0
HFD1_k127_3119901_26 COG2202 FOG PAS PAC domain - - - 0.0000000000000000508 95.0
HFD1_k127_3119901_27 monooxygenase activity - - - 0.0000000002944 65.0
HFD1_k127_3119901_29 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0002039 47.0
HFD1_k127_3119901_3 Ribulose bisphosphate carboxylase large chain, N-terminal domain K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 372.0
HFD1_k127_3119901_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 344.0
HFD1_k127_3119901_5 Flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 339.0
HFD1_k127_3119901_6 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000423 262.0
HFD1_k127_3119901_7 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000003389 258.0
HFD1_k127_3119901_8 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000466 242.0
HFD1_k127_3119901_9 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443,K16786,K16787 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000001831 210.0
HFD1_k127_3165257_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.393e-197 623.0
HFD1_k127_3165257_1 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 575.0
HFD1_k127_3165257_10 glycogen (starch) synthase activity K00703,K00754 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 340.0
HFD1_k127_3165257_11 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 325.0
HFD1_k127_3165257_12 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 338.0
HFD1_k127_3165257_13 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 311.0
HFD1_k127_3165257_14 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 307.0
HFD1_k127_3165257_15 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 303.0
HFD1_k127_3165257_16 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 301.0
HFD1_k127_3165257_17 Domains REC, HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004826 268.0
HFD1_k127_3165257_18 SMART Signal transduction response regulator, receiver region - - - 0.000000000000000000000000000000000000000000000000000000000000004548 219.0
HFD1_k127_3165257_19 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000006516 217.0
HFD1_k127_3165257_2 Aminotransferase K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 558.0
HFD1_k127_3165257_20 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000001981 216.0
HFD1_k127_3165257_21 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000001998 209.0
HFD1_k127_3165257_22 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000008456 151.0
HFD1_k127_3165257_23 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000004047 157.0
HFD1_k127_3165257_24 ECF sigma factor K03088 - - 0.0000000000000000000000000000000001259 141.0
HFD1_k127_3165257_25 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000006178 132.0
HFD1_k127_3165257_26 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000000000000000006282 130.0
HFD1_k127_3165257_27 Tetratricopeptide repeat - - - 0.00000000000000000000002831 106.0
HFD1_k127_3165257_28 cellulase activity - - - 0.0000000000000000729 93.0
HFD1_k127_3165257_29 Protein of unknown function (DUF3106) - - - 0.0000000003982 71.0
HFD1_k127_3165257_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 541.0
HFD1_k127_3165257_31 Putative zinc-finger - - - 0.000008735 54.0
HFD1_k127_3165257_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 509.0
HFD1_k127_3165257_5 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 496.0
HFD1_k127_3165257_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 408.0
HFD1_k127_3165257_7 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 391.0
HFD1_k127_3165257_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 382.0
HFD1_k127_3165257_9 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 387.0
HFD1_k127_3222168_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.322e-213 674.0
HFD1_k127_3222168_1 MazG family K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 298.0
HFD1_k127_3222168_2 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 277.0
HFD1_k127_3222168_3 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.000000000000000006244 93.0
HFD1_k127_3222168_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000196 94.0
HFD1_k127_3222168_5 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000009447 65.0
HFD1_k127_3222168_6 - - - - 0.000000009923 59.0
HFD1_k127_3222168_7 - - - - 0.000004933 49.0
HFD1_k127_3222168_8 ABC transporter (Permease) K01992 - - 0.00001786 56.0
HFD1_k127_3222168_9 - - - - 0.00008874 46.0
HFD1_k127_3231664_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 524.0
HFD1_k127_3231664_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000639 282.0
HFD1_k127_3231664_10 SAM-dependent RNA methyltransferase - - - 0.000000000000000000000000000000000000000000000006969 188.0
HFD1_k127_3231664_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000008392 148.0
HFD1_k127_3231664_12 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000004329 161.0
HFD1_k127_3231664_13 Zinc ion binding K11997,K12035 GO:0003008,GO:0003012,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007610,GO:0007626,GO:0008150,GO:0008152,GO:0008270,GO:0008345,GO:0009653,GO:0009987,GO:0010927,GO:0016043,GO:0016567,GO:0016740,GO:0019538,GO:0019725,GO:0019787,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030537,GO:0031032,GO:0031674,GO:0032446,GO:0032501,GO:0032502,GO:0032989,GO:0036211,GO:0042592,GO:0042692,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0046716,GO:0046872,GO:0046914,GO:0048468,GO:0048646,GO:0048747,GO:0048856,GO:0048869,GO:0051146,GO:0055001,GO:0055002,GO:0060249,GO:0061061,GO:0065007,GO:0065008,GO:0070647,GO:0070925,GO:0071704,GO:0071840,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901564 2.3.2.27 0.0000000000000000000000000000000001041 151.0
HFD1_k127_3231664_14 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000194 121.0
HFD1_k127_3231664_15 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000001885 120.0
HFD1_k127_3231664_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000001519 122.0
HFD1_k127_3231664_17 denitrification pathway K00380 - 1.8.1.2 0.000000000000000000000839 111.0
HFD1_k127_3231664_18 COG0607 Rhodanese-related sulfurtransferase K03406,K21028 - 2.8.1.11 0.000000000000000000001118 98.0
HFD1_k127_3231664_19 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.0000000000000000003909 102.0
HFD1_k127_3231664_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004358 241.0
HFD1_k127_3231664_20 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000001485 74.0
HFD1_k127_3231664_21 COG1404 Subtilisin-like serine proteases K13276 - - 0.0000000002653 73.0
HFD1_k127_3231664_22 NHL repeat containing protein - - - 0.000000004207 69.0
HFD1_k127_3231664_23 nitric oxide dioxygenase activity - - - 0.0000008347 61.0
HFD1_k127_3231664_3 Methyltransferase K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000001468 229.0
HFD1_k127_3231664_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000009205 223.0
HFD1_k127_3231664_5 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000002692 226.0
HFD1_k127_3231664_6 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000005965 194.0
HFD1_k127_3231664_7 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000000007624 188.0
HFD1_k127_3231664_8 denitrification pathway K00380 - 1.8.1.2 0.00000000000000000000000000000000000000000000000001642 203.0
HFD1_k127_3231664_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000009747 188.0
HFD1_k127_324784_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1610.0
HFD1_k127_324784_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 7.961e-255 810.0
HFD1_k127_324784_10 Type II/IV secretion system protein K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 327.0
HFD1_k127_324784_11 PFAM PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004001 258.0
HFD1_k127_324784_12 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000001009 239.0
HFD1_k127_324784_13 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000003335 229.0
HFD1_k127_324784_14 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000935 213.0
HFD1_k127_324784_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000005935 208.0
HFD1_k127_324784_16 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000001251 217.0
HFD1_k127_324784_17 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000001315 197.0
HFD1_k127_324784_18 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000003676 181.0
HFD1_k127_324784_19 repeat-containing protein - - - 0.000000000000000000000000000003073 134.0
HFD1_k127_324784_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 7.945e-241 767.0
HFD1_k127_324784_20 Glycosyl transferase family 41 - - - 0.0000000000000000000000003175 119.0
HFD1_k127_324784_21 histidine kinase - - - 0.000000000000000000000006751 116.0
HFD1_k127_324784_22 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000006029 101.0
HFD1_k127_324784_23 Domain of unknown function (DUF1858) - - - 0.0000000000000001544 83.0
HFD1_k127_324784_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.872e-227 728.0
HFD1_k127_324784_4 PFAM UvrD REP helicase K03657 - 3.6.4.12 6.37e-202 651.0
HFD1_k127_324784_5 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 519.0
HFD1_k127_324784_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 464.0
HFD1_k127_324784_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 392.0
HFD1_k127_324784_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 361.0
HFD1_k127_324784_9 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 334.0
HFD1_k127_3255772_0 Belongs to the acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001985 253.0
HFD1_k127_3255772_1 Phosphate acetyl/butaryl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000474 249.0
HFD1_k127_3255772_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000632 162.0
HFD1_k127_3255772_3 - - - - 0.00000000000003421 83.0
HFD1_k127_3311009_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.923e-251 784.0
HFD1_k127_3311009_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000001962 251.0
HFD1_k127_3311009_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000304 61.0
HFD1_k127_3313054_0 4Fe-4S dicluster domain - - - 4.415e-222 698.0
HFD1_k127_3313054_1 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 586.0
HFD1_k127_3313054_10 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000008969 81.0
HFD1_k127_3313054_2 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 523.0
HFD1_k127_3313054_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 486.0
HFD1_k127_3313054_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000002206 198.0
HFD1_k127_3313054_5 DsrE/DsrF-like family K07235 - - 0.000000000000000000000000000000000000000000000006435 174.0
HFD1_k127_3313054_6 PFAM DsrE family protein K07236 - - 0.000000000000000000000000000000000000007289 147.0
HFD1_k127_3313054_7 lyase activity - - - 0.000000000000000000000000000000000009865 144.0
HFD1_k127_3313054_8 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.00000000000000000000000000000000008208 137.0
HFD1_k127_3313054_9 PFAM DsrH family protein K07237 - - 0.0000000000000000000000005367 107.0
HFD1_k127_3377656_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.977e-282 886.0
HFD1_k127_3377656_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 523.0
HFD1_k127_3377656_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 298.0
HFD1_k127_3377656_3 Proteasome subunit K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000433 245.0
HFD1_k127_3377656_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000003961 195.0
HFD1_k127_3536929_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 4.441e-231 743.0
HFD1_k127_3536929_1 isochorismatase K06901 - - 9.841e-223 700.0
HFD1_k127_3536929_10 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 480.0
HFD1_k127_3536929_11 N-4 methylation of cytosine K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 367.0
HFD1_k127_3536929_12 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 355.0
HFD1_k127_3536929_13 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 347.0
HFD1_k127_3536929_14 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 323.0
HFD1_k127_3536929_15 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 317.0
HFD1_k127_3536929_16 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 309.0
HFD1_k127_3536929_17 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 312.0
HFD1_k127_3536929_18 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 302.0
HFD1_k127_3536929_19 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 300.0
HFD1_k127_3536929_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 5.981e-204 646.0
HFD1_k127_3536929_20 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002986 275.0
HFD1_k127_3536929_21 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002342 251.0
HFD1_k127_3536929_22 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000002066 271.0
HFD1_k127_3536929_23 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002458 242.0
HFD1_k127_3536929_24 PFAM phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002769 224.0
HFD1_k127_3536929_25 Psort location Cytoplasmic, score K19824 - - 0.000000000000000000000000000000000000000000000000000000000002895 212.0
HFD1_k127_3536929_26 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000003094 213.0
HFD1_k127_3536929_27 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000004238 219.0
HFD1_k127_3536929_28 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000000000006304 208.0
HFD1_k127_3536929_29 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000004728 198.0
HFD1_k127_3536929_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 3.505e-197 626.0
HFD1_k127_3536929_30 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000007012 192.0
HFD1_k127_3536929_31 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000001119 192.0
HFD1_k127_3536929_32 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000003707 190.0
HFD1_k127_3536929_33 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000000001018 169.0
HFD1_k127_3536929_34 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000002536 174.0
HFD1_k127_3536929_35 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000003787 173.0
HFD1_k127_3536929_36 TPM domain K06872 - - 0.000000000000000000000000000000000000000005905 165.0
HFD1_k127_3536929_37 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000003708 155.0
HFD1_k127_3536929_38 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000001837 150.0
HFD1_k127_3536929_39 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000001756 128.0
HFD1_k127_3536929_4 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 582.0
HFD1_k127_3536929_40 RDD family - - - 0.000000000000000000000005796 108.0
HFD1_k127_3536929_41 Protein tyrosine kinase - - - 0.000000000000000000009564 102.0
HFD1_k127_3536929_42 PD-(D/E)XK nuclease superfamily - - - 0.00000000009855 76.0
HFD1_k127_3536929_43 Late competence development protein ComFB K02241 - - 0.00000005093 59.0
HFD1_k127_3536929_44 shape-determining protein MreD K03571 - - 0.000001971 57.0
HFD1_k127_3536929_45 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0004277 49.0
HFD1_k127_3536929_5 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 574.0
HFD1_k127_3536929_6 oxidase, subunit K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 534.0
HFD1_k127_3536929_7 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 515.0
HFD1_k127_3536929_8 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 504.0
HFD1_k127_3536929_9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 477.0
HFD1_k127_3579138_0 Glycosyltransferase WbsX - - - 7.621e-290 917.0
HFD1_k127_3579138_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 483.0
HFD1_k127_3579138_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002841 278.0
HFD1_k127_3579138_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001963 262.0
HFD1_k127_3579138_4 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000002495 210.0
HFD1_k127_3579138_5 Acyltransferase family - - - 0.000000000000000000000000000000000236 145.0
HFD1_k127_3579138_6 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000008322 139.0
HFD1_k127_3598105_0 Belongs to the transketolase family K00615 - 2.2.1.1 3.378e-275 861.0
HFD1_k127_3598105_1 Sugar (and other) transporter K03446 - - 1.173e-197 629.0
HFD1_k127_3598105_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 391.0
HFD1_k127_3598105_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 366.0
HFD1_k127_3598105_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 368.0
HFD1_k127_3598105_5 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 348.0
HFD1_k127_3598105_6 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001594 250.0
HFD1_k127_3598105_7 AMP binding - - - 0.0000000000000000000000000000000000003849 150.0
HFD1_k127_3598105_8 Rubredoxin - - - 0.00000000000000000009783 91.0
HFD1_k127_3604755_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 437.0
HFD1_k127_3604755_1 glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000812 211.0
HFD1_k127_3604755_2 Glycosyl transferase - - - 0.0000000000000000000000003371 108.0
HFD1_k127_3604755_3 Tetratricopeptide repeat - - - 0.000005539 52.0
HFD1_k127_366926_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 503.0
HFD1_k127_366926_1 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 482.0
HFD1_k127_366926_10 - - - - 0.00000000001042 77.0
HFD1_k127_366926_11 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.00001434 48.0
HFD1_k127_366926_2 FAD linked oxidase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 477.0
HFD1_k127_366926_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 301.0
HFD1_k127_366926_4 PFAM Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009495 290.0
HFD1_k127_366926_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000008993 176.0
HFD1_k127_366926_6 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000000000000004185 134.0
HFD1_k127_366926_7 PFAM Rhodanese-like domain - - - 0.000000000000000000000001776 111.0
HFD1_k127_366926_8 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000003444 97.0
HFD1_k127_366926_9 Putative regulatory protein - - - 0.0000000000000009893 78.0
HFD1_k127_3669556_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 547.0
HFD1_k127_3669556_1 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 499.0
HFD1_k127_3669556_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 484.0
HFD1_k127_3669556_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 408.0
HFD1_k127_3669556_4 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 338.0
HFD1_k127_3669556_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000004029 234.0
HFD1_k127_3669556_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000009113 232.0
HFD1_k127_3669556_7 Binds the 23S rRNA K02909 - - 0.000000000000000000000000002222 112.0
HFD1_k127_3674040_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.187e-238 746.0
HFD1_k127_3674040_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.173e-232 725.0
HFD1_k127_3674040_10 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
HFD1_k127_3674040_11 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000001156 203.0
HFD1_k127_3674040_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000001638 139.0
HFD1_k127_3674040_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000001703 118.0
HFD1_k127_3674040_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000006942 106.0
HFD1_k127_3674040_16 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000001669 99.0
HFD1_k127_3674040_17 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000005399 74.0
HFD1_k127_3674040_18 Belongs to the ompA family K03640 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 - 0.000000000007837 72.0
HFD1_k127_3674040_19 - - - - 0.00003726 47.0
HFD1_k127_3674040_2 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 501.0
HFD1_k127_3674040_3 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 408.0
HFD1_k127_3674040_4 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 406.0
HFD1_k127_3674040_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 343.0
HFD1_k127_3674040_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 338.0
HFD1_k127_3674040_7 ATP synthase K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 295.0
HFD1_k127_3674040_8 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002766 278.0
HFD1_k127_3674040_9 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006617 270.0
HFD1_k127_3749680_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 2.997e-261 824.0
HFD1_k127_3749680_1 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 453.0
HFD1_k127_3749680_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 299.0
HFD1_k127_3749680_11 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004092 279.0
HFD1_k127_3749680_12 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006496 272.0
HFD1_k127_3749680_13 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000001555 246.0
HFD1_k127_3749680_14 electron transfer activity K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000004928 236.0
HFD1_k127_3749680_15 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000006433 226.0
HFD1_k127_3749680_16 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000003584 174.0
HFD1_k127_3749680_18 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000006038 85.0
HFD1_k127_3749680_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 447.0
HFD1_k127_3749680_3 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 381.0
HFD1_k127_3749680_4 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 366.0
HFD1_k127_3749680_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 336.0
HFD1_k127_3749680_6 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 317.0
HFD1_k127_3749680_7 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 310.0
HFD1_k127_3749680_8 regulatory protein IclR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 307.0
HFD1_k127_3749680_9 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 299.0
HFD1_k127_3752249_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1197.0
HFD1_k127_3752249_1 Biotin-protein ligase, N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001198 284.0
HFD1_k127_3752249_10 transferase activity, transferring glycosyl groups - - - 0.0003989 50.0
HFD1_k127_3752249_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000593 259.0
HFD1_k127_3752249_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001054 233.0
HFD1_k127_3752249_4 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000003759 205.0
HFD1_k127_3752249_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000000000002321 148.0
HFD1_k127_3752249_6 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.000000000000000000000000000000002402 134.0
HFD1_k127_3752249_7 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000003435 117.0
HFD1_k127_3752249_8 Domain of unknown function (DUF1736) - - - 0.0000000001238 74.0
HFD1_k127_3752249_9 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000001551 70.0
HFD1_k127_383331_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 3.353e-248 777.0
HFD1_k127_383331_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 3.1e-225 712.0
HFD1_k127_383331_10 Belongs to the 5'(3')-deoxyribonucleotidase family K05967 - - 0.00000000001283 72.0
HFD1_k127_383331_11 denitrification pathway - - - 0.0000000001679 74.0
HFD1_k127_383331_12 Mut7-C ubiquitin K03154 - - 0.0000000627 59.0
HFD1_k127_383331_2 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 615.0
HFD1_k127_383331_3 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001827 272.0
HFD1_k127_383331_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000001322 234.0
HFD1_k127_383331_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000002473 182.0
HFD1_k127_383331_6 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000002345 120.0
HFD1_k127_383331_7 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000007801 104.0
HFD1_k127_383331_8 protein histidine kinase activity K13924 - 2.1.1.80,3.1.1.61 0.0000000000002301 79.0
HFD1_k127_383331_9 EamA-like transporter family - - - 0.00000000000143 78.0
HFD1_k127_383815_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K05299 - 1.17.1.10,1.17.1.9 4.676e-282 892.0
HFD1_k127_383815_1 Pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 9.905e-234 738.0
HFD1_k127_383815_10 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001587 290.0
HFD1_k127_383815_11 Evidence 4 Homologs of previously reported genes of K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004539 267.0
HFD1_k127_383815_12 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000005313 246.0
HFD1_k127_383815_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001188 229.0
HFD1_k127_383815_14 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000001484 229.0
HFD1_k127_383815_15 MOSC domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000547 214.0
HFD1_k127_383815_16 molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000000002073 199.0
HFD1_k127_383815_17 COG2199 FOG GGDEF domain - - - 0.0000000000000000000000000000000000000000003504 178.0
HFD1_k127_383815_18 COG2143 Thioredoxin-related protein - - - 0.000000000000000000000000000000000002208 143.0
HFD1_k127_383815_19 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000002127 148.0
HFD1_k127_383815_2 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 610.0
HFD1_k127_383815_20 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000002063 117.0
HFD1_k127_383815_21 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000002248 116.0
HFD1_k127_383815_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000006456 111.0
HFD1_k127_383815_23 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000000001979 105.0
HFD1_k127_383815_24 COG2143 Thioredoxin-related protein - - - 0.0000000000000000000000245 107.0
HFD1_k127_383815_25 - - - - 0.00000000000000000008078 97.0
HFD1_k127_383815_26 COG2143 Thioredoxin-related protein - - - 0.00000000000000005374 87.0
HFD1_k127_383815_27 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000916 83.0
HFD1_k127_383815_28 Copper resistance protein CopZ K07213 - - 0.000000000000004688 77.0
HFD1_k127_383815_29 Rubrerythrin - - - 0.00000000002552 70.0
HFD1_k127_383815_3 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 447.0
HFD1_k127_383815_30 monooxygenase activity K06966 - 3.2.2.10 0.0000000007614 65.0
HFD1_k127_383815_31 - - - - 0.00000000721 66.0
HFD1_k127_383815_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 430.0
HFD1_k127_383815_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 425.0
HFD1_k127_383815_6 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 421.0
HFD1_k127_383815_7 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 337.0
HFD1_k127_383815_9 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001226 297.0
HFD1_k127_388889_0 Patatin-like phospholipase K07001 - - 3.476e-198 627.0
HFD1_k127_388889_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 363.0
HFD1_k127_388889_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 344.0
HFD1_k127_388889_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002601 270.0
HFD1_k127_388889_4 Iron-sulfur cluster-binding domain K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000002843 229.0
HFD1_k127_388889_5 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000000000000000000000000004427 203.0
HFD1_k127_388889_6 - - - - 0.00000000000000000000000000000000000000000001035 177.0
HFD1_k127_388889_7 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000001432 117.0
HFD1_k127_388889_8 Putative MetA-pathway of phenol degradation - - - 0.000000000000003716 78.0
HFD1_k127_388889_9 belongs to the glycosyl hydrolase 13 family K01176,K01208 GO:0005575,GO:0005576 3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000005715 86.0
HFD1_k127_3946734_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 3.135e-242 766.0
HFD1_k127_3946734_1 SMART Elongator protein 3 MiaB NifB - - - 1.719e-234 730.0
HFD1_k127_3946734_2 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 409.0
HFD1_k127_3946734_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000001469 180.0
HFD1_k127_3946734_4 methyltransferase - - - 0.0000000000000000000009623 99.0
HFD1_k127_3946734_5 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000007762 66.0
HFD1_k127_3946734_6 peroxiredoxin activity K01607 - 4.1.1.44 0.0000008623 56.0
HFD1_k127_3995854_0 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 342.0
HFD1_k127_3995854_1 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
HFD1_k127_3995854_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000000000000000001505 198.0
HFD1_k127_3995854_11 PFAM Glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000000000000000000445 205.0
HFD1_k127_3995854_12 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000001299 186.0
HFD1_k127_3995854_13 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.000000000000000000000000000000000000000000131 164.0
HFD1_k127_3995854_14 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000004253 166.0
HFD1_k127_3995854_15 cheY-homologous receiver domain - - - 0.0000000000000000000000000000001549 127.0
HFD1_k127_3995854_16 Universal stress protein family - - - 0.00000002113 62.0
HFD1_k127_3995854_17 Protein of unknown function (DUF2892) - - - 0.0005155 46.0
HFD1_k127_3995854_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 310.0
HFD1_k127_3995854_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 295.0
HFD1_k127_3995854_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 306.0
HFD1_k127_3995854_5 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000235 306.0
HFD1_k127_3995854_6 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002531 275.0
HFD1_k127_3995854_7 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006046 271.0
HFD1_k127_3995854_8 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006082 260.0
HFD1_k127_3995854_9 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000006154 224.0
HFD1_k127_400873_0 elongation factor G K02355 - - 4.65e-211 687.0
HFD1_k127_400873_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 504.0
HFD1_k127_400873_10 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000001083 174.0
HFD1_k127_400873_11 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000003722 171.0
HFD1_k127_400873_12 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000007639 162.0
HFD1_k127_400873_13 HEPN domain - - - 0.000000000000000000000000000000000000003725 149.0
HFD1_k127_400873_14 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000002829 128.0
HFD1_k127_400873_15 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000000006818 106.0
HFD1_k127_400873_16 Regulatory protein - - - 0.0000000000000000000005461 102.0
HFD1_k127_400873_17 PFAM DNA polymerase beta domain protein region - - - 0.000000000000000005895 87.0
HFD1_k127_400873_18 - - - - 0.00000000000000002964 89.0
HFD1_k127_400873_19 - - - - 0.000003583 49.0
HFD1_k127_400873_2 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 445.0
HFD1_k127_400873_20 PFAM PEGA domain - - - 0.0000471 53.0
HFD1_k127_400873_21 Protein tyrosine kinase - - - 0.0001062 51.0
HFD1_k127_400873_22 solute binding protein K02035 - - 0.0001343 50.0
HFD1_k127_400873_24 dehydrogenase - - - 0.0008996 43.0
HFD1_k127_400873_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 442.0
HFD1_k127_400873_4 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 377.0
HFD1_k127_400873_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 286.0
HFD1_k127_400873_6 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 283.0
HFD1_k127_400873_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000001742 263.0
HFD1_k127_400873_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000007592 211.0
HFD1_k127_400873_9 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000003154 208.0
HFD1_k127_4035161_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 457.0
HFD1_k127_4035161_1 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 389.0
HFD1_k127_4035161_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 397.0
HFD1_k127_4035161_3 TIGRFAM phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000001468 250.0
HFD1_k127_4035161_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000001502 218.0
HFD1_k127_4035161_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000002395 193.0
HFD1_k127_4035161_6 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000001046 131.0
HFD1_k127_4035161_7 Recombinase zinc beta ribbon domain - - - 0.00001359 48.0
HFD1_k127_4100361_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 321.0
HFD1_k127_4100361_1 cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000004231 243.0
HFD1_k127_4100361_2 - - - - 0.000000000000001777 88.0
HFD1_k127_4102380_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 4.598e-247 778.0
HFD1_k127_4102380_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 480.0
HFD1_k127_4102380_10 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000001813 199.0
HFD1_k127_4102380_11 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000000001626 161.0
HFD1_k127_4102380_12 Methyltransferase domain - - - 0.00000000000000000000926 100.0
HFD1_k127_4102380_13 Fe-S oxidoreductase - - - 0.0000000000000006542 87.0
HFD1_k127_4102380_14 - - - - 0.000000001044 63.0
HFD1_k127_4102380_15 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K12276 - - 0.0003254 48.0
HFD1_k127_4102380_2 Sigma-54 interaction domain K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 445.0
HFD1_k127_4102380_3 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 419.0
HFD1_k127_4102380_4 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 383.0
HFD1_k127_4102380_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 337.0
HFD1_k127_4102380_6 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 319.0
HFD1_k127_4102380_7 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 296.0
HFD1_k127_4102380_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000007107 259.0
HFD1_k127_4102380_9 TIGRFAM iron-sulfur cluster binding protein - - - 0.000000000000000000000000000000000000000000000000000000001595 208.0
HFD1_k127_4153692_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1956.0
HFD1_k127_4153692_1 DNA-directed 5'-3' RNA polymerase activity K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1657.0
HFD1_k127_4153692_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1075.0
HFD1_k127_4153692_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000004898 234.0
HFD1_k127_4153692_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000001169 225.0
HFD1_k127_4153692_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001658 79.0
HFD1_k127_4165062_0 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 413.0
HFD1_k127_4165062_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000005646 146.0
HFD1_k127_4179259_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.711e-213 676.0
HFD1_k127_4179259_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 574.0
HFD1_k127_4179259_10 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000003508 162.0
HFD1_k127_4179259_11 PFAM Cupin domain - - - 0.0000000000000000000000000000000000001617 150.0
HFD1_k127_4179259_12 S4 domain protein - - - 0.000000000000000001971 89.0
HFD1_k127_4179259_13 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000004512 71.0
HFD1_k127_4179259_14 TIGRFAM histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000145 54.0
HFD1_k127_4179259_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 404.0
HFD1_k127_4179259_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 404.0
HFD1_k127_4179259_4 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 331.0
HFD1_k127_4179259_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000003749 257.0
HFD1_k127_4179259_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000001666 203.0
HFD1_k127_4179259_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000007131 203.0
HFD1_k127_4179259_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.000000000000000000000000000000000000000000031 168.0
HFD1_k127_4179259_9 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000000000000000005864 154.0
HFD1_k127_4297407_0 Aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 605.0
HFD1_k127_4297407_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 507.0
HFD1_k127_4297407_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 455.0
HFD1_k127_4297407_3 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 377.0
HFD1_k127_4297407_4 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 291.0
HFD1_k127_4297407_5 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000002207 183.0
HFD1_k127_4297407_6 Histidine kinase - - - 0.0000000000000000000000000001452 130.0
HFD1_k127_4299167_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 527.0
HFD1_k127_4299167_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 510.0
HFD1_k127_4299167_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000001357 160.0
HFD1_k127_4299167_11 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000001826 135.0
HFD1_k127_4299167_12 DivIVA protein K04074 - - 0.00000000000000000000000000003786 122.0
HFD1_k127_4299167_13 YGGT family K02221 - - 0.0000000000000000000000000001141 121.0
HFD1_k127_4299167_14 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000007655 110.0
HFD1_k127_4299167_15 - - - - 0.00000000000000000000001102 106.0
HFD1_k127_4299167_16 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000001307 109.0
HFD1_k127_4299167_17 regulatory protein RecX K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000001949 93.0
HFD1_k127_4299167_18 Cupin 2, conserved barrel domain protein - - - 0.000000000000000003667 87.0
HFD1_k127_4299167_19 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000001726 82.0
HFD1_k127_4299167_2 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 503.0
HFD1_k127_4299167_20 phosphorelay signal transduction system K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.000000000000002993 81.0
HFD1_k127_4299167_21 Domain of unknown function (DUF1858) - - - 0.000000000001156 71.0
HFD1_k127_4299167_22 DsrE/DsrF-like family K07236 - - 0.00000000001296 69.0
HFD1_k127_4299167_23 DsrE/DsrF-like family - - - 0.00000000009358 66.0
HFD1_k127_4299167_24 4Fe-4S binding domain - - - 0.000004436 49.0
HFD1_k127_4299167_25 tRNA wobble position uridine thiolation K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000007511 51.0
HFD1_k127_4299167_3 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 496.0
HFD1_k127_4299167_4 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000002672 267.0
HFD1_k127_4299167_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001316 250.0
HFD1_k127_4299167_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000002752 236.0
HFD1_k127_4299167_7 - - - - 0.000000000000000000000000000000000000000000000000000003213 199.0
HFD1_k127_4299167_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000957 198.0
HFD1_k127_4299167_9 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000005832 168.0
HFD1_k127_4434836_0 Polysulphide reductase, NrfD - - - 9.19e-197 631.0
HFD1_k127_4434836_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 586.0
HFD1_k127_4434836_10 PFAM Rubrerythrin - - - 0.00000008488 60.0
HFD1_k127_4434836_11 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000001031 61.0
HFD1_k127_4434836_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 415.0
HFD1_k127_4434836_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000007566 219.0
HFD1_k127_4434836_4 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000003665 220.0
HFD1_k127_4434836_5 NHL repeat - - - 0.0000000000000000000000000000000000000004 168.0
HFD1_k127_4434836_6 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000001144 136.0
HFD1_k127_4434836_7 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000001013 125.0
HFD1_k127_4434836_8 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000007507 81.0
HFD1_k127_4434836_9 Serine threonine protein kinase - - - 0.000000000009607 78.0
HFD1_k127_4468962_0 Amino acid permease - - - 1.962e-226 716.0
HFD1_k127_4468962_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 327.0
HFD1_k127_4542316_0 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 478.0
HFD1_k127_4542316_1 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 364.0
HFD1_k127_4542316_2 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000007298 239.0
HFD1_k127_4542316_3 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000002435 235.0
HFD1_k127_4542316_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000403 139.0
HFD1_k127_4542316_5 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000001715 133.0
HFD1_k127_4645631_0 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002856 281.0
HFD1_k127_4645631_1 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000641 219.0
HFD1_k127_4645631_2 AAA domain K08252 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000009956 209.0
HFD1_k127_4645631_3 Transcription termination factor nusG - - - 0.000000000000000000232 91.0
HFD1_k127_4645631_4 - - - - 0.0000000000008378 77.0
HFD1_k127_4680552_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 6.902e-238 746.0
HFD1_k127_4680552_1 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 525.0
HFD1_k127_4680552_2 PAS domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 485.0
HFD1_k127_4680552_3 heptosyltransferase K02843 - - 0.0000000000001922 82.0
HFD1_k127_4826039_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 469.0
HFD1_k127_4826039_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 453.0
HFD1_k127_4826039_10 NosL - - - 0.00000000004906 69.0
HFD1_k127_4826039_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001153 286.0
HFD1_k127_4826039_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002414 263.0
HFD1_k127_4826039_4 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000005941 231.0
HFD1_k127_4826039_5 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.000000000000000000000000000000000000000000000000000000000001776 221.0
HFD1_k127_4826039_6 PFAM Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000004596 175.0
HFD1_k127_4826039_7 monooxygenase activity - - - 0.000000000000000000000000000000000002865 142.0
HFD1_k127_4826039_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000008345 105.0
HFD1_k127_4826039_9 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000003419 85.0
HFD1_k127_4827955_0 response to heat K03696 - - 2.203e-306 958.0
HFD1_k127_4827955_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 324.0
HFD1_k127_4827955_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 313.0
HFD1_k127_4827955_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
HFD1_k127_4827955_4 Lipoate--protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000008269 234.0
HFD1_k127_4827955_5 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.000000000000000000000000000000000000000000000000000003491 199.0
HFD1_k127_4827955_6 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000004499 160.0
HFD1_k127_4843570_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.521e-203 653.0
HFD1_k127_4843570_1 Orn/Lys/Arg decarboxylase, C-terminal domain K01582,K01585 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.18,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 561.0
HFD1_k127_4843570_2 Deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 509.0
HFD1_k127_4843570_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 399.0
HFD1_k127_4843570_4 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000009732 246.0
HFD1_k127_4843570_5 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000006823 211.0
HFD1_k127_4843570_6 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000001427 139.0
HFD1_k127_4858039_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 4.549e-295 918.0
HFD1_k127_4858039_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.023e-284 887.0
HFD1_k127_4858039_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 333.0
HFD1_k127_4858039_11 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 331.0
HFD1_k127_4858039_12 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 315.0
HFD1_k127_4858039_13 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 301.0
HFD1_k127_4858039_14 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 299.0
HFD1_k127_4858039_15 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 284.0
HFD1_k127_4858039_16 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002315 283.0
HFD1_k127_4858039_17 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002103 293.0
HFD1_k127_4858039_18 PFAM MscS Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001234 260.0
HFD1_k127_4858039_19 HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000001805 234.0
HFD1_k127_4858039_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 9.036e-195 615.0
HFD1_k127_4858039_20 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001422 222.0
HFD1_k127_4858039_21 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000002049 221.0
HFD1_k127_4858039_22 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000004591 184.0
HFD1_k127_4858039_23 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000001275 180.0
HFD1_k127_4858039_24 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000008042 154.0
HFD1_k127_4858039_25 Methylates ribosomal protein L11 K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000002006 149.0
HFD1_k127_4858039_26 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000597 121.0
HFD1_k127_4858039_27 holo-[acyl-carrier-protein] synthase activity K00997 - 2.7.8.7 0.0000000000000000000000000001076 120.0
HFD1_k127_4858039_28 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000007797 108.0
HFD1_k127_4858039_29 Protein of unknown function, DUF488 - - - 0.00000000000000001485 89.0
HFD1_k127_4858039_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 597.0
HFD1_k127_4858039_30 Tetratricopeptide repeat - - - 0.0000000000000417 83.0
HFD1_k127_4858039_31 Protein of unknown function, DUF488 - - - 0.00000000000009661 76.0
HFD1_k127_4858039_32 PFAM CBS domain - - - 0.0000000000001451 74.0
HFD1_k127_4858039_4 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 583.0
HFD1_k127_4858039_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 510.0
HFD1_k127_4858039_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 470.0
HFD1_k127_4858039_7 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 417.0
HFD1_k127_4858039_8 TIGRFAM Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 393.0
HFD1_k127_4858039_9 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 348.0
HFD1_k127_4892080_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 2.188e-240 755.0
HFD1_k127_4892080_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.476e-208 658.0
HFD1_k127_4892080_10 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 363.0
HFD1_k127_4892080_11 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 345.0
HFD1_k127_4892080_12 Histidine kinase K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 342.0
HFD1_k127_4892080_13 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 334.0
HFD1_k127_4892080_14 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000194 270.0
HFD1_k127_4892080_15 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002591 250.0
HFD1_k127_4892080_16 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000003783 184.0
HFD1_k127_4892080_17 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000004773 168.0
HFD1_k127_4892080_18 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000107 163.0
HFD1_k127_4892080_19 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001641 157.0
HFD1_k127_4892080_2 Sigma-54 interaction domain - - - 4.581e-205 646.0
HFD1_k127_4892080_20 - - - - 0.00000000000000000001223 93.0
HFD1_k127_4892080_21 Acetoacetate decarboxylase (ADC) - - - 0.000000000001004 77.0
HFD1_k127_4892080_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.767e-204 653.0
HFD1_k127_4892080_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 524.0
HFD1_k127_4892080_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 501.0
HFD1_k127_4892080_6 ABC transporter, ATP-binding protein K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 488.0
HFD1_k127_4892080_7 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 389.0
HFD1_k127_4892080_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 385.0
HFD1_k127_4892080_9 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 372.0
HFD1_k127_4896824_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1183.0
HFD1_k127_4896824_1 Acyl transferase domain K15314 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 356.0
HFD1_k127_4896824_2 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000002826 157.0
HFD1_k127_4896824_3 Rubredoxin - - - 0.000000000000000000000000107 108.0
HFD1_k127_4896824_4 - - - - 0.0000000001048 70.0
HFD1_k127_4899408_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 6.725e-283 900.0
HFD1_k127_4899408_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 502.0
HFD1_k127_4899408_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 405.0
HFD1_k127_4899408_3 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000001801 209.0
HFD1_k127_4899408_4 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000001901 172.0
HFD1_k127_4899408_5 - - - - 0.0000000000000000000000000000000000002999 147.0
HFD1_k127_4899408_6 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000002093 68.0
HFD1_k127_4905139_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 3.124e-205 655.0
HFD1_k127_4905139_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 535.0
HFD1_k127_4905139_10 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000932 237.0
HFD1_k127_4905139_11 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000002189 174.0
HFD1_k127_4905139_12 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000004625 153.0
HFD1_k127_4905139_13 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000001744 145.0
HFD1_k127_4905139_14 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000006081 67.0
HFD1_k127_4905139_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 521.0
HFD1_k127_4905139_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 377.0
HFD1_k127_4905139_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 386.0
HFD1_k127_4905139_5 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 374.0
HFD1_k127_4905139_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 295.0
HFD1_k127_4905139_7 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 299.0
HFD1_k127_4905139_8 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004624 274.0
HFD1_k127_4905139_9 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000003725 252.0
HFD1_k127_495_0 Catalyzes the synthesis of GMP from XMP K01951,K03790 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 7.495e-213 672.0
HFD1_k127_495_1 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001255 274.0
HFD1_k127_495_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000006702 231.0
HFD1_k127_495_3 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000103 162.0
HFD1_k127_495_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000009163 142.0
HFD1_k127_495_5 Methyltransferase type 11 - - - 0.000000000000445 80.0
HFD1_k127_495_6 Tetratricopeptide repeat - - - 0.0008007 44.0
HFD1_k127_4984215_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 4.25e-214 677.0
HFD1_k127_4984215_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.185e-195 628.0
HFD1_k127_4984215_10 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002993 259.0
HFD1_k127_4984215_11 polyketide synthase K21792 - - 0.000000000000000000000000000000000000000000000000000000000000006694 228.0
HFD1_k127_4984215_12 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000006802 210.0
HFD1_k127_4984215_13 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000001102 220.0
HFD1_k127_4984215_14 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000007299 177.0
HFD1_k127_4984215_15 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000131 166.0
HFD1_k127_4984215_16 PAP2 superfamily - - - 0.00000000000000000000000000000000006546 145.0
HFD1_k127_4984215_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000002484 109.0
HFD1_k127_4984215_19 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000001009 109.0
HFD1_k127_4984215_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 582.0
HFD1_k127_4984215_20 CAAX protease self-immunity - - - 0.0000000000000000000839 98.0
HFD1_k127_4984215_21 phytol kinase activity K16368 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006629,GO:0006644,GO:0006650,GO:0006654,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046473,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0098827,GO:1901576 2.7.1.174 0.0000000000000002771 86.0
HFD1_k127_4984215_22 - - - - 0.0000008644 58.0
HFD1_k127_4984215_24 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0006192 51.0
HFD1_k127_4984215_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 516.0
HFD1_k127_4984215_4 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 496.0
HFD1_k127_4984215_5 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 491.0
HFD1_k127_4984215_6 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 478.0
HFD1_k127_4984215_7 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 353.0
HFD1_k127_4984215_8 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 351.0
HFD1_k127_4984215_9 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003098 261.0
HFD1_k127_5048394_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 521.0
HFD1_k127_5048394_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 337.0
HFD1_k127_5048394_2 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000000001069 229.0
HFD1_k127_5048394_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00000002025 55.0
HFD1_k127_5048394_5 - - - - 0.00004116 48.0
HFD1_k127_5103854_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 602.0
HFD1_k127_5103854_1 lysine 2,3-aminomutase activity K01843,K19810 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 572.0
HFD1_k127_5103854_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 526.0
HFD1_k127_5103854_3 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 445.0
HFD1_k127_5103854_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 323.0
HFD1_k127_5103854_5 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000000000000000000001172 187.0
HFD1_k127_5103854_6 self proteolysis - - - 0.0000000000000000000000000000000000000000000002106 183.0
HFD1_k127_5103854_7 response regulator K02667 - - 0.0000000000000000000000000000000000001123 146.0
HFD1_k127_5103854_8 - - - - 0.0002231 46.0
HFD1_k127_5107073_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.554e-252 791.0
HFD1_k127_5107073_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.382e-247 777.0
HFD1_k127_5107073_10 pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.0000000000000000000000000001784 119.0
HFD1_k127_5107073_11 Polymer-forming cytoskeletal - - - 0.000000000000000000000006318 111.0
HFD1_k127_5107073_12 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000001115 100.0
HFD1_k127_5107073_13 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000001323 76.0
HFD1_k127_5107073_14 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000001162 68.0
HFD1_k127_5107073_15 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000004274 61.0
HFD1_k127_5107073_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 482.0
HFD1_k127_5107073_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 430.0
HFD1_k127_5107073_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 364.0
HFD1_k127_5107073_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 365.0
HFD1_k127_5107073_6 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 317.0
HFD1_k127_5107073_7 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001839 276.0
HFD1_k127_5107073_8 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000001956 205.0
HFD1_k127_5107073_9 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000002662 139.0
HFD1_k127_5119884_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.605e-226 715.0
HFD1_k127_5119884_1 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 464.0
HFD1_k127_5119884_2 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 410.0
HFD1_k127_5119884_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000004666 187.0
HFD1_k127_5119884_4 PFAM Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000003485 109.0
HFD1_k127_5119884_5 Nitrogen-fixing NifU domain protein - - - 0.00000000000000000000004654 99.0
HFD1_k127_5119884_6 electron transfer activity K05337 - - 0.00000000000001068 76.0
HFD1_k127_5119884_7 - - - - 0.000000000001075 70.0
HFD1_k127_5139850_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 380.0
HFD1_k127_5139850_1 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000001182 241.0
HFD1_k127_5139850_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000001392 154.0
HFD1_k127_5139850_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000002541 118.0
HFD1_k127_5139850_4 polyribonucleotide nucleotidyltransferase activity K02945,K03527,K07571,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 0.000000001593 59.0
HFD1_k127_5152341_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 544.0
HFD1_k127_5152341_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 537.0
HFD1_k127_5152341_10 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000004186 194.0
HFD1_k127_5152341_11 Transport permease protein K09690 - - 0.0000000000000000000000000000000000000000000000000008346 194.0
HFD1_k127_5152341_12 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000003841 186.0
HFD1_k127_5152341_13 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000003427 142.0
HFD1_k127_5152341_14 PhoQ Sensor K07636 - 2.7.13.3 0.0000000000000000001325 90.0
HFD1_k127_5152341_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 430.0
HFD1_k127_5152341_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 335.0
HFD1_k127_5152341_4 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 326.0
HFD1_k127_5152341_5 Glycosyl transferase, family 2 K00721,K07011,K13005,K20444 - 2.4.1.60,2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000001533 269.0
HFD1_k127_5152341_6 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001243 246.0
HFD1_k127_5152341_7 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000006392 214.0
HFD1_k127_5152341_8 Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000002625 210.0
HFD1_k127_5152341_9 - K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000001788 210.0
HFD1_k127_5165696_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 421.0
HFD1_k127_5165696_1 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 363.0
HFD1_k127_5165696_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 286.0
HFD1_k127_5165696_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000001267 198.0
HFD1_k127_5165696_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000021 174.0
HFD1_k127_5165696_5 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000004793 182.0
HFD1_k127_5165696_6 - - - - 0.0000000000000000000000000000000000001132 157.0
HFD1_k127_5165696_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000133 157.0
HFD1_k127_5165696_8 Amidohydrolase family K20810 - 3.5.4.40 0.000000000000000000000000000000009822 135.0
HFD1_k127_5172533_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1142.0
HFD1_k127_5172533_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 5.605e-241 768.0
HFD1_k127_5172533_10 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 376.0
HFD1_k127_5172533_11 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 341.0
HFD1_k127_5172533_12 AhpC/TSA family K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 295.0
HFD1_k127_5172533_13 BadF BadG BcrA BcrD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001005 277.0
HFD1_k127_5172533_14 PFAM HhH-GPD family protein K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000005012 252.0
HFD1_k127_5172533_15 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431,K12251 - 3.5.1.53,3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000002206 241.0
HFD1_k127_5172533_16 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000005904 249.0
HFD1_k127_5172533_17 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000005982 224.0
HFD1_k127_5172533_18 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000001123 221.0
HFD1_k127_5172533_19 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000005037 218.0
HFD1_k127_5172533_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 595.0
HFD1_k127_5172533_20 PFAM Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000469 184.0
HFD1_k127_5172533_21 - - - - 0.000000000000000000000000000000008341 130.0
HFD1_k127_5172533_22 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000008807 129.0
HFD1_k127_5172533_23 Methyltransferase domain - - - 0.00000000000000000000000000002601 125.0
HFD1_k127_5172533_24 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000006711 107.0
HFD1_k127_5172533_26 Lipid A 3-O-deacylase (PagL) - - - 0.0000007324 60.0
HFD1_k127_5172533_27 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0002115 47.0
HFD1_k127_5172533_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 573.0
HFD1_k127_5172533_4 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 492.0
HFD1_k127_5172533_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 472.0
HFD1_k127_5172533_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 447.0
HFD1_k127_5172533_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 400.0
HFD1_k127_5172533_8 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 384.0
HFD1_k127_5172533_9 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 369.0
HFD1_k127_5223002_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 449.0
HFD1_k127_5223002_1 PFAM Cytochrome b5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000017 266.0
HFD1_k127_5223002_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000001238 194.0
HFD1_k127_5223002_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000003408 161.0
HFD1_k127_5223002_4 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000001374 145.0
HFD1_k127_5223002_5 Belongs to the thioredoxin family K03671 - - 0.000000000000000000004304 102.0
HFD1_k127_5223002_6 nuclease - - - 0.00000000000000004951 84.0
HFD1_k127_5223002_7 - - - - 0.0000000000001161 76.0
HFD1_k127_5279120_0 SMART ATPase, AAA type, core K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 393.0
HFD1_k127_5279120_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000122 205.0
HFD1_k127_5279120_2 macromolecule localization K09690 - - 0.00000000000000000000000000000000000000000000000000003679 195.0
HFD1_k127_5279120_3 PFAM Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000002021 108.0
HFD1_k127_5378334_0 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 425.0
HFD1_k127_5378334_1 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 441.0
HFD1_k127_5378334_2 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000004583 148.0
HFD1_k127_5378334_3 Pilus assembly protein K02662 - - 0.000000000000000000000000003326 123.0
HFD1_k127_5378334_5 PFAM Fimbrial assembly family protein K02461,K02662,K02663,K12289 - - 0.00004962 53.0
HFD1_k127_5378334_6 - K02664 - - 0.0003404 52.0
HFD1_k127_5442072_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0 1016.0
HFD1_k127_5442072_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.195e-293 923.0
HFD1_k127_5442072_10 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 515.0
HFD1_k127_5442072_11 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 506.0
HFD1_k127_5442072_12 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 516.0
HFD1_k127_5442072_13 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 497.0
HFD1_k127_5442072_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 444.0
HFD1_k127_5442072_15 TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
HFD1_k127_5442072_16 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 400.0
HFD1_k127_5442072_17 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 377.0
HFD1_k127_5442072_18 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 378.0
HFD1_k127_5442072_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 376.0
HFD1_k127_5442072_2 Acyl-CoA synthetase (NDP forming) K09181 - - 3.898e-226 720.0
HFD1_k127_5442072_20 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 374.0
HFD1_k127_5442072_21 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 370.0
HFD1_k127_5442072_22 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 349.0
HFD1_k127_5442072_23 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 357.0
HFD1_k127_5442072_24 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 337.0
HFD1_k127_5442072_25 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 323.0
HFD1_k127_5442072_26 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 355.0
HFD1_k127_5442072_27 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 312.0
HFD1_k127_5442072_28 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 305.0
HFD1_k127_5442072_29 DRTGG domain protein K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 304.0
HFD1_k127_5442072_3 Flavin containing amine oxidoreductase - - - 1.132e-222 700.0
HFD1_k127_5442072_30 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001343 300.0
HFD1_k127_5442072_31 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003644 304.0
HFD1_k127_5442072_32 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002295 280.0
HFD1_k127_5442072_33 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000484 276.0
HFD1_k127_5442072_34 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000122 272.0
HFD1_k127_5442072_35 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005778 248.0
HFD1_k127_5442072_36 PFAM ApbE family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000002981 239.0
HFD1_k127_5442072_37 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001146 255.0
HFD1_k127_5442072_38 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000001954 244.0
HFD1_k127_5442072_39 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000004684 229.0
HFD1_k127_5442072_4 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 2.498e-211 682.0
HFD1_k127_5442072_40 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000003301 249.0
HFD1_k127_5442072_41 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000003388 209.0
HFD1_k127_5442072_42 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000001083 197.0
HFD1_k127_5442072_43 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000001033 184.0
HFD1_k127_5442072_44 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000001908 173.0
HFD1_k127_5442072_45 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000001338 191.0
HFD1_k127_5442072_46 - - - - 0.00000000000000000000000000000000000000000000366 185.0
HFD1_k127_5442072_47 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000002524 176.0
HFD1_k127_5442072_48 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000003209 165.0
HFD1_k127_5442072_49 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000001318 151.0
HFD1_k127_5442072_5 Conserved hypothetical protein 698 - - - 3.816e-211 665.0
HFD1_k127_5442072_50 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000002362 152.0
HFD1_k127_5442072_51 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000004531 149.0
HFD1_k127_5442072_52 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000001492 145.0
HFD1_k127_5442072_53 response regulator - - - 0.0000000000000000000000000000000000002101 156.0
HFD1_k127_5442072_54 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000668 141.0
HFD1_k127_5442072_55 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.0000000000000000000000000000000003239 134.0
HFD1_k127_5442072_56 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000003611 126.0
HFD1_k127_5442072_57 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000408 129.0
HFD1_k127_5442072_58 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000007258 121.0
HFD1_k127_5442072_59 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000003421 118.0
HFD1_k127_5442072_6 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 4.293e-204 652.0
HFD1_k127_5442072_60 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000000000000000000003318 116.0
HFD1_k127_5442072_62 denitrification pathway K03620 - - 0.00000000000000000003662 107.0
HFD1_k127_5442072_63 Protein of unknown function (DUF507) - - - 0.000000000000000001125 91.0
HFD1_k127_5442072_64 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000007642 95.0
HFD1_k127_5442072_65 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000001043 85.0
HFD1_k127_5442072_66 Protein of unknown function (DUF507) K09804 - - 0.0000000000001316 74.0
HFD1_k127_5442072_67 Domain of unknown function DUF302 - - - 0.0000000000001432 78.0
HFD1_k127_5442072_68 PFAM formylmethanofuran dehydrogenase subunit E K11261 - 1.2.7.12 0.000000000002498 75.0
HFD1_k127_5442072_69 - - - - 0.000000000004622 69.0
HFD1_k127_5442072_7 Endoribonuclease that initiates mRNA decay K18682 - - 7.512e-195 620.0
HFD1_k127_5442072_70 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000001447 74.0
HFD1_k127_5442072_72 HEAT repeat - - - 0.00000001057 66.0
HFD1_k127_5442072_73 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000003901 66.0
HFD1_k127_5442072_74 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.0000004024 64.0
HFD1_k127_5442072_75 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000006859 59.0
HFD1_k127_5442072_76 - - - - 0.00009933 52.0
HFD1_k127_5442072_8 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 586.0
HFD1_k127_5442072_9 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 546.0
HFD1_k127_5444616_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.212e-279 869.0
HFD1_k127_5444616_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 377.0
HFD1_k127_5444616_2 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008064 279.0
HFD1_k127_5444616_3 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001412 277.0
HFD1_k127_5444616_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009592 277.0
HFD1_k127_5444616_5 Belongs to the Fur family K09825 - - 0.00000000000000000000000000000000000000000000001343 174.0
HFD1_k127_5444616_6 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000001964 151.0
HFD1_k127_5444616_7 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.000000000000000000000000000000000000005518 147.0
HFD1_k127_5444616_8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0006156 49.0
HFD1_k127_544475_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1153.0
HFD1_k127_544475_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 563.0
HFD1_k127_544475_10 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 314.0
HFD1_k127_544475_11 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 324.0
HFD1_k127_544475_12 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 306.0
HFD1_k127_544475_13 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 295.0
HFD1_k127_544475_14 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 293.0
HFD1_k127_544475_15 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 307.0
HFD1_k127_544475_16 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 286.0
HFD1_k127_544475_17 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001611 284.0
HFD1_k127_544475_18 alginic acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006501 254.0
HFD1_k127_544475_19 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008789 243.0
HFD1_k127_544475_2 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 512.0
HFD1_k127_544475_20 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000002364 247.0
HFD1_k127_544475_21 domain protein - - - 0.000000000000000000000000000000000000000000000000000002354 207.0
HFD1_k127_544475_22 Polypeptide deformylase K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000002737 186.0
HFD1_k127_544475_23 alginic acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000007375 190.0
HFD1_k127_544475_24 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000001281 178.0
HFD1_k127_544475_25 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000002494 177.0
HFD1_k127_544475_26 - - - - 0.0000000000000000000000000000000000000000000002986 181.0
HFD1_k127_544475_27 ResB-like family - - - 0.000000000000000000000000000000000000000000004165 180.0
HFD1_k127_544475_28 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.000000000000000000000000000000000000000003778 165.0
HFD1_k127_544475_29 HEAT repeat - - - 0.00000000000000000000000000000000000213 153.0
HFD1_k127_544475_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 486.0
HFD1_k127_544475_30 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.000000000000000000000000000000000002496 145.0
HFD1_k127_544475_31 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000008141 134.0
HFD1_k127_544475_33 4Fe-4S binding domain - - - 0.00000000000000000000000000000005809 133.0
HFD1_k127_544475_34 alginic acid biosynthetic process - - - 0.00000000000000000000000000000006482 138.0
HFD1_k127_544475_35 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000002156 126.0
HFD1_k127_544475_36 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000000000001501 123.0
HFD1_k127_544475_37 alginic acid biosynthetic process - - - 0.00000000000000000000000000001656 126.0
HFD1_k127_544475_38 Transcriptional regulator K13640 - - 0.00000000000000000000000000001804 120.0
HFD1_k127_544475_39 cell redox homeostasis - - - 0.00000000000000000000002785 100.0
HFD1_k127_544475_4 Large extracellular alpha-helical protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 481.0
HFD1_k127_544475_40 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000122 100.0
HFD1_k127_544475_41 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000001107 96.0
HFD1_k127_544475_42 PFAM Thioredoxin K03671 - - 0.00000000000000001148 93.0
HFD1_k127_544475_43 translation initiation factor activity K00694 - 2.4.1.12 0.00000000000002572 86.0
HFD1_k127_544475_44 - - - - 0.00000000004039 65.0
HFD1_k127_544475_45 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000005386 70.0
HFD1_k127_544475_46 Tetratricopeptide repeat - - - 0.0004594 51.0
HFD1_k127_544475_5 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 388.0
HFD1_k127_544475_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 379.0
HFD1_k127_544475_7 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 359.0
HFD1_k127_544475_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 334.0
HFD1_k127_544475_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 331.0
HFD1_k127_5521578_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.222e-275 863.0
HFD1_k127_5521578_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.01e-256 819.0
HFD1_k127_5521578_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000293 271.0
HFD1_k127_5521578_11 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000001879 257.0
HFD1_k127_5521578_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000511 238.0
HFD1_k127_5521578_13 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000001014 204.0
HFD1_k127_5521578_14 - - - - 0.00000000000000000000000000000000000000000000000000000001288 208.0
HFD1_k127_5521578_15 NUDIX domain K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.00000000000000000000000000000000000000000000000009372 180.0
HFD1_k127_5521578_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000002555 183.0
HFD1_k127_5521578_17 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000002098 176.0
HFD1_k127_5521578_18 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000007172 171.0
HFD1_k127_5521578_19 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000000000136 169.0
HFD1_k127_5521578_2 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 571.0
HFD1_k127_5521578_20 MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000003437 162.0
HFD1_k127_5521578_21 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000000000000021 157.0
HFD1_k127_5521578_22 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000003668 138.0
HFD1_k127_5521578_23 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000009921 138.0
HFD1_k127_5521578_24 Ribosome-binding factor A K02834 - - 0.0000000000000000000000000000001572 126.0
HFD1_k127_5521578_25 - - - - 0.00000000000000000000000005137 108.0
HFD1_k127_5521578_26 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000008118 97.0
HFD1_k127_5521578_27 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.00000000000000000004652 97.0
HFD1_k127_5521578_28 Protein of unknown function (DUF503) K09764 - - 0.000000000000000001569 91.0
HFD1_k127_5521578_29 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000001584 89.0
HFD1_k127_5521578_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 548.0
HFD1_k127_5521578_30 biopolymer transport protein K03559,K03560 - - 0.0000000000011 78.0
HFD1_k127_5521578_31 - - - - 0.000008762 55.0
HFD1_k127_5521578_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 432.0
HFD1_k127_5521578_5 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 415.0
HFD1_k127_5521578_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 418.0
HFD1_k127_5521578_7 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 392.0
HFD1_k127_5521578_8 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 300.0
HFD1_k127_5521578_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
HFD1_k127_5544265_0 PFAM type II secretion system protein E K02283,K03609 - - 9.197e-195 618.0
HFD1_k127_5544265_1 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 432.0
HFD1_k127_5544265_10 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000004867 105.0
HFD1_k127_5544265_11 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000002702 99.0
HFD1_k127_5544265_2 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 396.0
HFD1_k127_5544265_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001158 256.0
HFD1_k127_5544265_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003724 254.0
HFD1_k127_5544265_5 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000004765 235.0
HFD1_k127_5544265_6 NUBPL iron-transfer P-loop NTPase K02282 - - 0.000000000000000000000000000000000000000000000000000000000000005835 231.0
HFD1_k127_5544265_7 Flp pilus assembly protein K12511 - - 0.0000000000000000000000000000000000000000000000000000000000003073 222.0
HFD1_k127_5544265_8 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.00000000000000000000000000000000000000000004784 180.0
HFD1_k127_5544265_9 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000001161 144.0
HFD1_k127_554556_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 612.0
HFD1_k127_554556_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 430.0
HFD1_k127_554556_10 Rubrerythrin K19824 - - 0.000000000000000000000000000000000000462 146.0
HFD1_k127_554556_11 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000001789 153.0
HFD1_k127_554556_12 - - - - 0.000000000000000000000000002218 115.0
HFD1_k127_554556_13 - - - - 0.000000000000000000000000007481 121.0
HFD1_k127_554556_15 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000001533 94.0
HFD1_k127_554556_16 - - - - 0.00000002403 64.0
HFD1_k127_554556_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 406.0
HFD1_k127_554556_3 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 374.0
HFD1_k127_554556_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 331.0
HFD1_k127_554556_5 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008614 270.0
HFD1_k127_554556_6 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000001008 246.0
HFD1_k127_554556_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000001195 158.0
HFD1_k127_554556_8 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000001114 154.0
HFD1_k127_554556_9 membrane K00389 - - 0.0000000000000000000000000000000000001623 154.0
HFD1_k127_5546174_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.078e-205 648.0
HFD1_k127_5546174_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 470.0
HFD1_k127_5546174_2 Glycosyl hydrolase family 57 K22278 - 3.5.1.104 0.00000000000000000000000000000000000000002135 163.0
HFD1_k127_5546174_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000001739 134.0
HFD1_k127_5697011_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 6.912e-272 861.0
HFD1_k127_5697011_1 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 445.0
HFD1_k127_5697011_10 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 307.0
HFD1_k127_5697011_11 Iron-only hydrogenase maturation rSAM protein HydG K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 288.0
HFD1_k127_5697011_12 PFAM Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006186 272.0
HFD1_k127_5697011_13 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000001935 263.0
HFD1_k127_5697011_14 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001668 252.0
HFD1_k127_5697011_15 PFAM ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000007535 233.0
HFD1_k127_5697011_16 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000008754 195.0
HFD1_k127_5697011_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000005319 204.0
HFD1_k127_5697011_18 NifQ K15790 - - 0.000000000000000000000000000000000000000003401 157.0
HFD1_k127_5697011_19 Nitrogen regulatory protein P-II K02589 - - 0.0000000000000000000000000000000000000008258 156.0
HFD1_k127_5697011_2 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 415.0
HFD1_k127_5697011_20 Dinitrogenase iron-molybdenum cofactor K02596 - - 0.000000000000000000000000000000000000003815 150.0
HFD1_k127_5697011_21 Nitrogen regulatory protein P-II K02590 - - 0.000000000000000000000000000000004021 134.0
HFD1_k127_5697011_22 Putative RNA methylase family UPF0020 K03427 - 2.1.1.72 0.0000000000000000000000000000157 118.0
HFD1_k127_5697011_23 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000192 127.0
HFD1_k127_5697011_24 4Fe-4S binding domain - - - 0.00000000000000000000000003724 111.0
HFD1_k127_5697011_25 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000006857 120.0
HFD1_k127_5697011_26 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000001923 97.0
HFD1_k127_5697011_27 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000004616 76.0
HFD1_k127_5697011_28 Domain of unknown function (DUF4082) - - - 0.000000000000005387 91.0
HFD1_k127_5697011_29 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000004125 79.0
HFD1_k127_5697011_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 395.0
HFD1_k127_5697011_30 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000001636 73.0
HFD1_k127_5697011_31 Chaperone protein DNAj - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0000005484 62.0
HFD1_k127_5697011_32 Domain of unknown function (DUF4082) - - - 0.00002425 59.0
HFD1_k127_5697011_33 sequence-specific DNA binding - - - 0.0002511 49.0
HFD1_k127_5697011_4 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 378.0
HFD1_k127_5697011_5 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 364.0
HFD1_k127_5697011_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 379.0
HFD1_k127_5697011_7 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 355.0
HFD1_k127_5697011_8 S-layer homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 381.0
HFD1_k127_5697011_9 Elongator protein 3, MiaB family, Radical SAM K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 326.0
HFD1_k127_5793866_0 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 549.0
HFD1_k127_5793866_1 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000008489 109.0
HFD1_k127_5793866_3 Protein of unknown function (DUF1018) - - - 0.00000000006922 68.0
HFD1_k127_5793866_5 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000001197 55.0
HFD1_k127_5800453_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 6.04e-267 830.0
HFD1_k127_5800453_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 468.0
HFD1_k127_5800453_10 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001648 228.0
HFD1_k127_5800453_11 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000001318 207.0
HFD1_k127_5800453_12 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000000000000000000000000000000000000000000000000000006051 195.0
HFD1_k127_5800453_13 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000000000001603 200.0
HFD1_k127_5800453_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000002739 191.0
HFD1_k127_5800453_15 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000003724 160.0
HFD1_k127_5800453_16 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000001502 164.0
HFD1_k127_5800453_17 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000003051 153.0
HFD1_k127_5800453_18 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000002619 145.0
HFD1_k127_5800453_19 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000002793 119.0
HFD1_k127_5800453_2 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 467.0
HFD1_k127_5800453_20 Universal stress protein K06149 - - 0.00000000000000000000000000003375 123.0
HFD1_k127_5800453_21 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair - - - 0.0000000000000000000000003092 113.0
HFD1_k127_5800453_22 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000002529 89.0
HFD1_k127_5800453_23 - - - - 0.0000000000000001637 82.0
HFD1_k127_5800453_24 PFAM RNP-1 like RNA-binding protein - - - 0.0000000003787 61.0
HFD1_k127_5800453_3 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 397.0
HFD1_k127_5800453_4 Belongs to the precorrin methyltransferase family K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 307.0
HFD1_k127_5800453_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 303.0
HFD1_k127_5800453_6 Glutamine amido-transferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002077 263.0
HFD1_k127_5800453_7 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000006953 268.0
HFD1_k127_5800453_8 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 259.0
HFD1_k127_5800453_9 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934,K21479 - 2.1.1.131,2.1.1.272 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 259.0
HFD1_k127_5827297_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 553.0
HFD1_k127_5827297_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000002728 78.0
HFD1_k127_5876248_0 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 3.458e-263 821.0
HFD1_k127_5876248_1 DNA polymerase alpha chain like domain K02347 - - 1.005e-223 708.0
HFD1_k127_5876248_10 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 297.0
HFD1_k127_5876248_11 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 309.0
HFD1_k127_5876248_12 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000000000000000000000000000000000000000000000005581 254.0
HFD1_k127_5876248_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000001448 231.0
HFD1_k127_5876248_14 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000236 207.0
HFD1_k127_5876248_15 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000001197 144.0
HFD1_k127_5876248_16 coenzyme binding K07071 - - 0.0000000000000000000000000000000000003975 154.0
HFD1_k127_5876248_17 metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000002596 151.0
HFD1_k127_5876248_18 response regulator - - - 0.000000000000000000000000003823 119.0
HFD1_k127_5876248_19 Psort location Cytoplasmic, score - - - 0.0000000000000000000000002278 108.0
HFD1_k127_5876248_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 549.0
HFD1_k127_5876248_20 NmrA-like family - - - 0.0000000000000002599 91.0
HFD1_k127_5876248_21 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.000000000000001176 78.0
HFD1_k127_5876248_23 SMART phosphoesterase PHP domain protein - - - 0.00000007014 63.0
HFD1_k127_5876248_24 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K01841 - 5.4.2.9 0.0003287 53.0
HFD1_k127_5876248_25 Rubrerythrin - - - 0.0004985 49.0
HFD1_k127_5876248_3 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 547.0
HFD1_k127_5876248_4 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 527.0
HFD1_k127_5876248_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 527.0
HFD1_k127_5876248_6 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 493.0
HFD1_k127_5876248_7 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 448.0
HFD1_k127_5876248_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 366.0
HFD1_k127_5876248_9 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 364.0
HFD1_k127_5894787_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 353.0
HFD1_k127_5894787_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 314.0
HFD1_k127_5894787_2 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 289.0
HFD1_k127_5894787_3 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001442 283.0
HFD1_k127_5894787_4 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002157 263.0
HFD1_k127_5894787_5 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000008236 154.0
HFD1_k127_5894787_6 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000008841 147.0
HFD1_k127_5894787_7 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000009583 153.0
HFD1_k127_5894787_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000002219 91.0
HFD1_k127_6061594_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 470.0
HFD1_k127_6061594_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 428.0
HFD1_k127_6061594_10 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000001174 177.0
HFD1_k127_6061594_11 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000006405 154.0
HFD1_k127_6061594_12 12 heme-binding sites - - - 0.0000000000000000000000000000000000000003278 164.0
HFD1_k127_6061594_13 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000486 160.0
HFD1_k127_6061594_14 von Willebrand factor (vWF) type D domain - - - 0.00000000000000000000000000000000000108 157.0
HFD1_k127_6061594_15 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000005178 143.0
HFD1_k127_6061594_16 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000002876 134.0
HFD1_k127_6061594_2 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 375.0
HFD1_k127_6061594_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 330.0
HFD1_k127_6061594_4 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 338.0
HFD1_k127_6061594_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 288.0
HFD1_k127_6061594_6 4Fe-4S ferredoxin K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003132 246.0
HFD1_k127_6061594_7 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000004249 215.0
HFD1_k127_6061594_8 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000001537 173.0
HFD1_k127_6061594_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000005039 186.0
HFD1_k127_6066289_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.374e-217 696.0
HFD1_k127_6066289_1 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000002317 205.0
HFD1_k127_6066289_2 Autoinducer binding domain K20334 - - 0.00000000000000000000000000000000000000000000000000001136 197.0
HFD1_k127_6066289_3 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000000000000000000001613 177.0
HFD1_k127_6066289_4 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000002662 68.0
HFD1_k127_6066289_5 Autoinducer synthase - - - 0.00000000003 73.0
HFD1_k127_6067_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.574e-202 646.0
HFD1_k127_6067_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 597.0
HFD1_k127_6067_10 Roadblock/LC7 domain - - - 0.0000000000000000037 90.0
HFD1_k127_6067_11 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000036 72.0
HFD1_k127_6067_12 translation initiation factor activity K08086 - - 0.0001562 54.0
HFD1_k127_6067_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 496.0
HFD1_k127_6067_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 355.0
HFD1_k127_6067_4 COG0006 Xaa-Pro aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000001519 228.0
HFD1_k127_6067_5 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000002162 212.0
HFD1_k127_6067_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000006843 190.0
HFD1_k127_6067_7 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000004415 148.0
HFD1_k127_6067_8 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000000001002 127.0
HFD1_k127_6067_9 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.000000000000000002262 99.0
HFD1_k127_6094395_0 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 501.0
HFD1_k127_6094395_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 499.0
HFD1_k127_6094395_2 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004539 267.0
HFD1_k127_6094395_3 Recombination protein O C terminal K03584 - - 0.00000000000000000000000001734 120.0
HFD1_k127_6120882_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.499e-308 957.0
HFD1_k127_6120882_1 glycolate transport K14393 - - 2.49e-240 755.0
HFD1_k127_6120882_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 6.967e-240 757.0
HFD1_k127_6120882_3 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 363.0
HFD1_k127_6120882_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000001364 150.0
HFD1_k127_6120882_5 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000001438 120.0
HFD1_k127_6120882_6 phosphate-selective porin O and P K07221 - - 0.00000001883 67.0
HFD1_k127_6159508_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 580.0
HFD1_k127_6159508_1 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 329.0
HFD1_k127_6159508_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001782 274.0
HFD1_k127_6159508_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000001996 239.0
HFD1_k127_6159508_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000001936 110.0
HFD1_k127_6254146_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 607.0
HFD1_k127_6254146_1 Hydrogenase expression formation protein hypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 441.0
HFD1_k127_6254146_10 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 324.0
HFD1_k127_6254146_11 PFAM response regulator receiver K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 294.0
HFD1_k127_6254146_12 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 295.0
HFD1_k127_6254146_13 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003064 266.0
HFD1_k127_6254146_14 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003269 262.0
HFD1_k127_6254146_15 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000008789 203.0
HFD1_k127_6254146_16 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000001803 194.0
HFD1_k127_6254146_17 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000005806 190.0
HFD1_k127_6254146_18 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000179 195.0
HFD1_k127_6254146_19 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000009742 181.0
HFD1_k127_6254146_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 416.0
HFD1_k127_6254146_20 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000006504 158.0
HFD1_k127_6254146_21 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000001203 155.0
HFD1_k127_6254146_22 PTS system fructose IIA component K02793 - 2.7.1.191 0.00000000000000000000000000000009792 128.0
HFD1_k127_6254146_23 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000001019 119.0
HFD1_k127_6254146_24 phosphocarrier protein HPr K11189 - - 0.0000000000000000000000003239 107.0
HFD1_k127_6254146_25 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000009156 112.0
HFD1_k127_6254146_26 PilZ domain - - - 0.000000000000000000001231 100.0
HFD1_k127_6254146_27 HupF/HypC family K04653 - - 0.00000000000000005256 84.0
HFD1_k127_6254146_28 Histidine kinase - - - 0.0000000000000001161 87.0
HFD1_k127_6254146_29 OstA-like protein K09774 - - 0.0000000000000001683 87.0
HFD1_k127_6254146_3 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 401.0
HFD1_k127_6254146_30 Protein conserved in bacteria K11719 - - 0.00000000000001282 81.0
HFD1_k127_6254146_31 cell envelope organization K05807,K08309 - - 0.0000000000035 78.0
HFD1_k127_6254146_32 Belongs to the glycosyl hydrolase family 6 K01183 - 3.2.1.14 0.00000000003908 73.0
HFD1_k127_6254146_4 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 403.0
HFD1_k127_6254146_5 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 383.0
HFD1_k127_6254146_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 380.0
HFD1_k127_6254146_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 355.0
HFD1_k127_6254146_8 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 357.0
HFD1_k127_6254146_9 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 335.0
HFD1_k127_6321054_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 332.0
HFD1_k127_6321054_1 ubiE/COQ5 methyltransferase family K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 303.0
HFD1_k127_6321054_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008486 275.0
HFD1_k127_6321054_3 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002497 244.0
HFD1_k127_6321054_4 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000001212 208.0
HFD1_k127_6321054_5 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000000000003846 187.0
HFD1_k127_6321054_7 Family of unknown function (DUF5343) - - - 0.000000000000000000000000000000000004003 145.0
HFD1_k127_6321054_8 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000008808 142.0
HFD1_k127_6321054_9 - - - - 0.00000000000000000000000000001183 125.0
HFD1_k127_6430425_0 arsenite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 590.0
HFD1_k127_6430425_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 320.0
HFD1_k127_6430425_2 - K09771 - - 0.00000000000000000000000000000000000000009625 153.0
HFD1_k127_6430425_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000004457 66.0
HFD1_k127_6505689_0 PFAM Rh family protein ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 598.0
HFD1_k127_6505689_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 477.0
HFD1_k127_6505689_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 396.0
HFD1_k127_6505689_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 385.0
HFD1_k127_6505689_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000604 196.0
HFD1_k127_6505689_5 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000004484 201.0
HFD1_k127_6505689_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000000009274 179.0
HFD1_k127_6562089_0 Heterodisulfide reductase subunit A and related polyferredoxins K16886 - - 1.153e-290 910.0
HFD1_k127_6562089_1 reductase, alpha subunit K00394 - 1.8.99.2 1.527e-264 823.0
HFD1_k127_6562089_2 FAD dependent oxidoreductase K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 561.0
HFD1_k127_6562089_3 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 456.0
HFD1_k127_6562089_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 430.0
HFD1_k127_6562089_5 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 314.0
HFD1_k127_6562089_6 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000001278 226.0
HFD1_k127_6588565_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 404.0
HFD1_k127_6588565_1 metallopeptidase activity K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 326.0
HFD1_k127_6588565_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000273 211.0
HFD1_k127_6588565_3 Psort location CytoplasmicMembrane, score K00368 - 1.7.2.1 0.00000000000000000000000000001796 135.0
HFD1_k127_6593888_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 401.0
HFD1_k127_6593888_1 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006532 246.0
HFD1_k127_6593888_10 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000000000002004 72.0
HFD1_k127_6593888_11 PFAM Methyltransferase type 11 - - - 0.000000001229 67.0
HFD1_k127_6593888_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001445 245.0
HFD1_k127_6593888_3 Cytochrome b/b6/petB K03887 - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
HFD1_k127_6593888_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000007592 201.0
HFD1_k127_6593888_5 PFAM Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000001076 117.0
HFD1_k127_6593888_6 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000007913 110.0
HFD1_k127_6593888_7 Protein of unknown function (DUF1698) - - - 0.0000000000000000000002708 111.0
HFD1_k127_6593888_8 GYD family - - - 0.000000000000000001203 90.0
HFD1_k127_6639039_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 8.524e-208 657.0
HFD1_k127_6639039_1 Peroxidase K03782 - 1.11.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 576.0
HFD1_k127_6639039_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 350.0
HFD1_k127_6639039_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 335.0
HFD1_k127_6639039_4 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002297 280.0
HFD1_k127_6639039_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000331 252.0
HFD1_k127_6639039_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000002086 205.0
HFD1_k127_6639039_7 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000000009077 135.0
HFD1_k127_6639039_8 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000007534 136.0
HFD1_k127_6639039_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000286 116.0
HFD1_k127_6644615_0 AcrB/AcrD/AcrF family K03296,K19594 - - 0.0 1521.0
HFD1_k127_6644615_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.58e-301 956.0
HFD1_k127_6644615_10 Biotin-lipoyl like K19595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 444.0
HFD1_k127_6644615_11 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 408.0
HFD1_k127_6644615_12 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
HFD1_k127_6644615_13 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 337.0
HFD1_k127_6644615_14 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 319.0
HFD1_k127_6644615_15 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 316.0
HFD1_k127_6644615_16 Bacterial sugar transferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001463 287.0
HFD1_k127_6644615_17 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 274.0
HFD1_k127_6644615_18 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001955 261.0
HFD1_k127_6644615_19 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001167 263.0
HFD1_k127_6644615_2 nitrogenase component I, alpha chain K02586 - 1.18.6.1 2.711e-237 745.0
HFD1_k127_6644615_20 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000001426 209.0
HFD1_k127_6644615_21 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000003393 200.0
HFD1_k127_6644615_22 - - - - 0.0000000000000000000000000000000000000000000000000002645 190.0
HFD1_k127_6644615_23 TIGRFAM YD repeat protein - - - 0.0000000000000000000000000000000000000000000000006878 185.0
HFD1_k127_6644615_24 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000001297 189.0
HFD1_k127_6644615_25 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000001234 163.0
HFD1_k127_6644615_26 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000003659 165.0
HFD1_k127_6644615_27 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000004155 145.0
HFD1_k127_6644615_28 Histidine kinase - - - 0.000000000000000000000000000000000004425 147.0
HFD1_k127_6644615_29 Fibronectin type 3 domain K20276 - - 0.000000000000000000000000000000000006279 160.0
HFD1_k127_6644615_3 Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L- methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by K22466 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 552.0
HFD1_k127_6644615_30 Belongs to the UPF0251 family - - - 0.000000000000000000000000002339 120.0
HFD1_k127_6644615_31 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000005913 97.0
HFD1_k127_6644615_32 - K02009 - - 0.00000000000000000002221 101.0
HFD1_k127_6644615_33 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000202 83.0
HFD1_k127_6644615_34 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000002285 89.0
HFD1_k127_6644615_35 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000001786 78.0
HFD1_k127_6644615_36 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000006871 74.0
HFD1_k127_6644615_37 ATP synthase B/B' CF(0) K02109 - - 0.000000002165 68.0
HFD1_k127_6644615_38 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000001136 53.0
HFD1_k127_6644615_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 551.0
HFD1_k127_6644615_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 531.0
HFD1_k127_6644615_6 GAF domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 521.0
HFD1_k127_6644615_7 CobB/CobQ-like glutamine amidotransferase domain K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 512.0
HFD1_k127_6644615_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 508.0
HFD1_k127_6644615_9 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588,K04037,K11333 - 1.18.6.1,1.3.7.14,1.3.7.15,1.3.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 469.0
HFD1_k127_6653694_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 3.623e-194 629.0
HFD1_k127_6653694_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 485.0
HFD1_k127_6653694_10 Cell surface protein - - - 0.00000000000000000007607 106.0
HFD1_k127_6653694_11 - - - - 0.000006318 60.0
HFD1_k127_6653694_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 473.0
HFD1_k127_6653694_3 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 316.0
HFD1_k127_6653694_4 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 308.0
HFD1_k127_6653694_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 293.0
HFD1_k127_6653694_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002097 280.0
HFD1_k127_6653694_7 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000001044 248.0
HFD1_k127_6653694_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000103 201.0
HFD1_k127_6653694_9 Zincin-like metallopeptidase - - - 0.00000000000000000000000004479 113.0
HFD1_k127_674465_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 543.0
HFD1_k127_674465_1 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008821 259.0
HFD1_k127_674465_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000002926 222.0
HFD1_k127_674465_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000007497 99.0
HFD1_k127_674465_5 cheY-homologous receiver domain - - - 0.0001799 49.0
HFD1_k127_6762450_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 528.0
HFD1_k127_6762450_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 502.0
HFD1_k127_6762450_2 Dam-replacing family - - - 0.000000000000000000000000000000000000000000000000000000000000000000009516 241.0
HFD1_k127_6762450_3 Belongs to the ompA family K03286 - - 0.000000000000000004604 91.0
HFD1_k127_6792285_0 membrane transporter protein K07090 - - 2.154e-202 638.0
HFD1_k127_6792285_1 phosphorelay signal transduction system K02584,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 475.0
HFD1_k127_6792285_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000986 408.0
HFD1_k127_6792285_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001804 255.0
HFD1_k127_6792285_4 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000009816 218.0
HFD1_k127_6792285_5 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000004449 188.0
HFD1_k127_6792285_6 DNA-binding transcription factor activity K03710 - - 0.0000000000000000000000000000000004811 141.0
HFD1_k127_6792285_7 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000003267 133.0
HFD1_k127_6792285_8 PFAM UspA domain protein - - - 0.000006622 55.0
HFD1_k127_6792285_9 Belongs to the universal stress protein A family - - - 0.00006409 54.0
HFD1_k127_6864174_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1127.0
HFD1_k127_6864174_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.083e-268 842.0
HFD1_k127_6864174_10 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 297.0
HFD1_k127_6864174_11 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001433 279.0
HFD1_k127_6864174_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007137 279.0
HFD1_k127_6864174_13 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000005457 259.0
HFD1_k127_6864174_14 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002479 283.0
HFD1_k127_6864174_15 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
HFD1_k127_6864174_16 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000003358 223.0
HFD1_k127_6864174_17 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000001563 218.0
HFD1_k127_6864174_18 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000001458 211.0
HFD1_k127_6864174_19 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000003389 213.0
HFD1_k127_6864174_2 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 7.814e-204 651.0
HFD1_k127_6864174_20 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000008335 201.0
HFD1_k127_6864174_21 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000001072 174.0
HFD1_k127_6864174_22 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000002518 127.0
HFD1_k127_6864174_23 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000004204 137.0
HFD1_k127_6864174_24 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000032 115.0
HFD1_k127_6864174_25 Histidine kinase-like ATPases - - - 0.00000000000000000000003582 115.0
HFD1_k127_6864174_26 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000003019 97.0
HFD1_k127_6864174_27 Domain of unknown function (DUF4082) - - - 0.000000000000000008526 100.0
HFD1_k127_6864174_28 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000005611 86.0
HFD1_k127_6864174_29 Domain of unknown function (DUF4082) - - - 0.0000000000000247 89.0
HFD1_k127_6864174_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 606.0
HFD1_k127_6864174_30 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000003526 79.0
HFD1_k127_6864174_31 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000008966 73.0
HFD1_k127_6864174_32 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000003615 72.0
HFD1_k127_6864174_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 591.0
HFD1_k127_6864174_5 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 481.0
HFD1_k127_6864174_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 453.0
HFD1_k127_6864174_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 391.0
HFD1_k127_6864174_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 347.0
HFD1_k127_6864174_9 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 374.0
HFD1_k127_6879686_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 3.637e-239 756.0
HFD1_k127_6879686_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.431e-199 629.0
HFD1_k127_6879686_2 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 409.0
HFD1_k127_6879686_3 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003941 283.0
HFD1_k127_6879686_4 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000003397 186.0
HFD1_k127_6879686_5 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000000000000292 130.0
HFD1_k127_6879686_6 Peptidase family S49 K04773 - - 0.000000000000000000005085 96.0
HFD1_k127_7052222_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 463.0
HFD1_k127_7052222_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 312.0
HFD1_k127_7052222_10 PIN domain - - - 0.0000000000000000000000000000001617 127.0
HFD1_k127_7052222_11 SpoVT / AbrB like domain - - - 0.00000000000000007427 81.0
HFD1_k127_7052222_12 ATP-binding region, ATPase domain protein - - - 0.000000000000001277 81.0
HFD1_k127_7052222_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000667 282.0
HFD1_k127_7052222_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000001056 241.0
HFD1_k127_7052222_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000126 241.0
HFD1_k127_7052222_5 deoxyribose-phosphate aldolase activity K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000556 218.0
HFD1_k127_7052222_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000007667 206.0
HFD1_k127_7052222_7 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000004071 199.0
HFD1_k127_7052222_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000002904 179.0
HFD1_k127_7052222_9 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000003651 166.0
HFD1_k127_7085231_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.923e-206 653.0
HFD1_k127_7085231_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 337.0
HFD1_k127_7085231_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008323 282.0
HFD1_k127_7085231_3 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000002255 230.0
HFD1_k127_7085231_4 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000003524 204.0
HFD1_k127_7085231_5 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000002068 188.0
HFD1_k127_7085231_6 Von Willebrand factor type A domain K07114 - - 0.00000000000000000000000005554 123.0
HFD1_k127_7085231_7 Tetratricopeptide repeat - - - 0.0000000000002599 81.0
HFD1_k127_7085231_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000007908 73.0
HFD1_k127_7112440_0 Polyketide synthase dehydratase - - - 0.0 1422.0
HFD1_k127_7112440_1 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 8.02e-317 983.0
HFD1_k127_7112440_10 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000001596 165.0
HFD1_k127_7112440_11 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000004352 167.0
HFD1_k127_7112440_12 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000103 162.0
HFD1_k127_7112440_13 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000004838 129.0
HFD1_k127_7112440_14 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000006407 121.0
HFD1_k127_7112440_15 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000001319 98.0
HFD1_k127_7112440_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 488.0
HFD1_k127_7112440_3 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 439.0
HFD1_k127_7112440_4 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 431.0
HFD1_k127_7112440_5 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 434.0
HFD1_k127_7112440_6 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000006967 200.0
HFD1_k127_7112440_7 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001753 208.0
HFD1_k127_7112440_8 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000003051 179.0
HFD1_k127_7112440_9 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000000572 176.0
HFD1_k127_7120391_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.524e-226 723.0
HFD1_k127_7120391_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001929 262.0
HFD1_k127_7120391_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000002623 175.0
HFD1_k127_7120391_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000001212 159.0
HFD1_k127_7120391_4 cytochrome C biogenesis protein ResB K07399 - - 0.000000000000000001679 100.0
HFD1_k127_7120391_5 Thioredoxin - - - 0.0000000191 60.0
HFD1_k127_7214985_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 1.686e-229 723.0
HFD1_k127_7214985_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 578.0
HFD1_k127_7214985_10 -O-antigen K02847,K13009,K16705 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000003936 216.0
HFD1_k127_7214985_11 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000001929 196.0
HFD1_k127_7214985_12 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000000000000000000000000006184 119.0
HFD1_k127_7214985_13 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000000000000000000000001548 118.0
HFD1_k127_7214985_14 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000000000000000000000004397 108.0
HFD1_k127_7214985_15 COG3307 Lipid A core - O-antigen ligase and related enzymes K18814 - - 0.0000000000000000008356 101.0
HFD1_k127_7214985_16 transferase activity, transferring glycosyl groups - - - 0.000000000000005747 79.0
HFD1_k127_7214985_17 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000002076 58.0
HFD1_k127_7214985_2 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 529.0
HFD1_k127_7214985_3 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 490.0
HFD1_k127_7214985_4 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 400.0
HFD1_k127_7214985_5 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 381.0
HFD1_k127_7214985_6 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 338.0
HFD1_k127_7214985_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 315.0
HFD1_k127_7214985_8 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000003383 237.0
HFD1_k127_7214985_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006905 236.0
HFD1_k127_7243496_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.121e-265 833.0
HFD1_k127_7243496_1 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 477.0
HFD1_k127_7243496_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 314.0
HFD1_k127_7243496_3 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000353 88.0
HFD1_k127_7277850_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.103e-222 695.0
HFD1_k127_7277850_1 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 296.0
HFD1_k127_7277850_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006519 271.0
HFD1_k127_7330480_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 512.0
HFD1_k127_7330480_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 407.0
HFD1_k127_7330480_2 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006249 241.0
HFD1_k127_7330480_3 - - - - 0.0000000000000000000000000000000000000000000000000000000003776 213.0
HFD1_k127_7330480_4 - - - - 0.00000000000000000000000000000000000000000000000000001048 203.0
HFD1_k127_7333083_0 NAD synthase K01916 - 6.3.1.5 6.181e-214 680.0
HFD1_k127_7333083_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.635e-208 656.0
HFD1_k127_7333083_10 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 293.0
HFD1_k127_7333083_11 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 294.0
HFD1_k127_7333083_12 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001716 279.0
HFD1_k127_7333083_13 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005517 248.0
HFD1_k127_7333083_14 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000005958 230.0
HFD1_k127_7333083_15 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000003179 214.0
HFD1_k127_7333083_16 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000001591 227.0
HFD1_k127_7333083_17 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000001049 176.0
HFD1_k127_7333083_18 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000004769 186.0
HFD1_k127_7333083_19 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000002855 164.0
HFD1_k127_7333083_2 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 9.88e-204 644.0
HFD1_k127_7333083_20 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000002112 157.0
HFD1_k127_7333083_21 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000001607 130.0
HFD1_k127_7333083_22 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000002987 108.0
HFD1_k127_7333083_23 Domain of unknown function (DUF4412) - - - 0.0000000000000000000004705 105.0
HFD1_k127_7333083_24 signal-transduction protein containing cAMP-binding and CBS domains K00031,K14446 - 1.1.1.42,1.3.1.85 0.0000000000000000000009754 100.0
HFD1_k127_7333083_25 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000004703 98.0
HFD1_k127_7333083_3 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.341e-200 645.0
HFD1_k127_7333083_4 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 494.0
HFD1_k127_7333083_5 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 397.0
HFD1_k127_7333083_6 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 385.0
HFD1_k127_7333083_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 357.0
HFD1_k127_7333083_8 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 340.0
HFD1_k127_7333083_9 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 303.0
HFD1_k127_7362538_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 580.0
HFD1_k127_7362538_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 299.0
HFD1_k127_7362538_2 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 314.0
HFD1_k127_7362538_3 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001985 253.0
HFD1_k127_7362538_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000004057 234.0
HFD1_k127_7362538_5 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000001119 192.0
HFD1_k127_7362538_6 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000007684 167.0
HFD1_k127_7362538_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000002978 141.0
HFD1_k127_7362538_8 response regulator receiver K22010 - - 0.0000000000000000000000000005448 120.0
HFD1_k127_7365012_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1036.0
HFD1_k127_7365012_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.27e-281 881.0
HFD1_k127_7365012_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 411.0
HFD1_k127_7365012_11 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 337.0
HFD1_k127_7365012_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 340.0
HFD1_k127_7365012_13 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 315.0
HFD1_k127_7365012_14 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 296.0
HFD1_k127_7365012_15 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000998 288.0
HFD1_k127_7365012_16 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000003207 262.0
HFD1_k127_7365012_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000008378 255.0
HFD1_k127_7365012_18 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000002079 263.0
HFD1_k127_7365012_19 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000001734 238.0
HFD1_k127_7365012_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 558.0
HFD1_k127_7365012_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000002758 235.0
HFD1_k127_7365012_21 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000001175 235.0
HFD1_k127_7365012_22 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000008991 218.0
HFD1_k127_7365012_23 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000000002513 178.0
HFD1_k127_7365012_24 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000006471 181.0
HFD1_k127_7365012_25 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000003532 175.0
HFD1_k127_7365012_26 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.0000000000000000000000000000000001842 139.0
HFD1_k127_7365012_27 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001416 138.0
HFD1_k127_7365012_28 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000005532 120.0
HFD1_k127_7365012_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 481.0
HFD1_k127_7365012_30 Predicted membrane protein (DUF2232) - - - 0.0000000000000000000000000002399 126.0
HFD1_k127_7365012_31 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000001285 99.0
HFD1_k127_7365012_32 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000009817 96.0
HFD1_k127_7365012_33 protein secretion K03116 - - 0.00000000003018 65.0
HFD1_k127_7365012_4 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 479.0
HFD1_k127_7365012_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 475.0
HFD1_k127_7365012_6 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 470.0
HFD1_k127_7365012_7 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 473.0
HFD1_k127_7365012_8 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 456.0
HFD1_k127_7365012_9 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 445.0
HFD1_k127_7383530_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 481.0
HFD1_k127_7383530_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 320.0
HFD1_k127_7383530_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007521 273.0
HFD1_k127_7390910_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 5.062e-199 648.0
HFD1_k127_7390910_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 465.0
HFD1_k127_7390910_2 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 311.0
HFD1_k127_7390910_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000005436 267.0
HFD1_k127_7390910_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000003503 231.0
HFD1_k127_7390910_5 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000002399 217.0
HFD1_k127_7390910_6 cyclohydrolase K01746 - 4.3.1.4 0.000000000000000000000000000000000000000000000009152 178.0
HFD1_k127_7390910_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000005997 129.0
HFD1_k127_7390910_8 - - - - 0.0000000000000000000001326 106.0
HFD1_k127_7390910_9 Universal stress protein - - - 0.00000000005087 72.0
HFD1_k127_7392982_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.763e-245 775.0
HFD1_k127_7392982_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 572.0
HFD1_k127_7392982_10 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004871 279.0
HFD1_k127_7392982_11 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000002526 223.0
HFD1_k127_7392982_12 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000000000000000002721 227.0
HFD1_k127_7392982_13 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000001708 186.0
HFD1_k127_7392982_14 Histidine kinase - - - 0.000000000000000000000000000000000000000000000002401 194.0
HFD1_k127_7392982_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000005579 189.0
HFD1_k127_7392982_16 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000006778 167.0
HFD1_k127_7392982_17 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000001161 144.0
HFD1_k127_7392982_18 energy transducer activity K03832 - - 0.0000000000000000000000001114 117.0
HFD1_k127_7392982_19 phosphorelay signal transduction system - - - 0.0000000000000000000000006774 112.0
HFD1_k127_7392982_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 557.0
HFD1_k127_7392982_20 coenzyme binding K07071 - - 0.000000000000000000000004404 113.0
HFD1_k127_7392982_21 Type II and III secretion system protein K02666 - - 0.0000000000000001354 94.0
HFD1_k127_7392982_22 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.0000000000000008983 78.0
HFD1_k127_7392982_23 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000000004765 74.0
HFD1_k127_7392982_24 Pilus assembly protein, PilP K02665 - - 0.00000000000006856 82.0
HFD1_k127_7392982_25 Pilus assembly protein PilO K02664 - - 0.000002143 57.0
HFD1_k127_7392982_26 PFAM Fimbrial assembly K02663 - - 0.000003165 57.0
HFD1_k127_7392982_3 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 496.0
HFD1_k127_7392982_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 384.0
HFD1_k127_7392982_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 384.0
HFD1_k127_7392982_6 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 344.0
HFD1_k127_7392982_7 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 341.0
HFD1_k127_7392982_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 327.0
HFD1_k127_7392982_9 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 305.0
HFD1_k127_7462631_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 402.0
HFD1_k127_7462631_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 325.0
HFD1_k127_7462631_2 Ribosomal protein L3 K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001668 247.0
HFD1_k127_7462631_3 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000006708 220.0
HFD1_k127_7462631_4 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000005104 179.0
HFD1_k127_7462631_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000001113 150.0
HFD1_k127_7462631_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000007915 141.0
HFD1_k127_7462631_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000001316 139.0
HFD1_k127_7462631_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000006383 113.0
HFD1_k127_7507025_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.39e-284 899.0
HFD1_k127_7507025_1 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 1.283e-207 661.0
HFD1_k127_7507025_10 pfam abc K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 330.0
HFD1_k127_7507025_11 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 322.0
HFD1_k127_7507025_12 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 312.0
HFD1_k127_7507025_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 293.0
HFD1_k127_7507025_14 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009034 277.0
HFD1_k127_7507025_15 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002629 304.0
HFD1_k127_7507025_16 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004028 271.0
HFD1_k127_7507025_17 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005468 269.0
HFD1_k127_7507025_18 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000003384 240.0
HFD1_k127_7507025_19 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000003451 249.0
HFD1_k127_7507025_2 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 598.0
HFD1_k127_7507025_20 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000339 232.0
HFD1_k127_7507025_21 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000002535 219.0
HFD1_k127_7507025_22 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000003435 208.0
HFD1_k127_7507025_23 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000001045 192.0
HFD1_k127_7507025_24 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.00000000000000000000000000000000000000000000000009813 180.0
HFD1_k127_7507025_25 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000005464 159.0
HFD1_k127_7507025_26 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000000000000000000000001187 165.0
HFD1_k127_7507025_27 PFAM Archaeal ATPase - - - 0.00000000000000000000000000000000000000227 162.0
HFD1_k127_7507025_28 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.00000000000000000000000000000000000005884 157.0
HFD1_k127_7507025_29 Protein of unknown function (DUF1571) - - - 0.0000000000000000000000000000000000002468 150.0
HFD1_k127_7507025_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 571.0
HFD1_k127_7507025_30 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000481 102.0
HFD1_k127_7507025_31 - - - - 0.00000000000000002643 93.0
HFD1_k127_7507025_32 PFAM Cyclic nucleotide-binding domain - - - 0.00000000000000003062 87.0
HFD1_k127_7507025_33 Domain of unknown function (DUF1844) - - - 0.0000000000000001102 83.0
HFD1_k127_7507025_34 - - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000001272 81.0
HFD1_k127_7507025_35 protein transport across the cell outer membrane K02246,K08084 - - 0.00000001629 64.0
HFD1_k127_7507025_36 Bacterial Ig-like domain - - - 0.00000003857 68.0
HFD1_k127_7507025_37 peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000001027 61.0
HFD1_k127_7507025_39 Fibronectin type III domain protein - - - 0.00008468 57.0
HFD1_k127_7507025_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 477.0
HFD1_k127_7507025_5 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 427.0
HFD1_k127_7507025_6 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 390.0
HFD1_k127_7507025_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 344.0
HFD1_k127_7507025_8 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 374.0
HFD1_k127_7507025_9 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 338.0
HFD1_k127_7554887_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 461.0
HFD1_k127_7554887_1 TIGRFAM cysteine K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 430.0
HFD1_k127_7554887_2 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000006925 229.0
HFD1_k127_7554887_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000944 215.0
HFD1_k127_7554887_4 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000001366 186.0
HFD1_k127_7554887_5 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000001416 183.0
HFD1_k127_7554887_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000008274 114.0
HFD1_k127_7554887_7 cytochrome C peroxidase - - - 0.0000000000369 70.0
HFD1_k127_7554887_8 - - - - 0.00001063 51.0
HFD1_k127_7576425_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 579.0
HFD1_k127_7576425_1 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 453.0
HFD1_k127_7576425_10 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001131 83.0
HFD1_k127_7576425_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 420.0
HFD1_k127_7576425_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 384.0
HFD1_k127_7576425_4 PFAM Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 320.0
HFD1_k127_7576425_5 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 317.0
HFD1_k127_7576425_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 303.0
HFD1_k127_7576425_7 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000003443 259.0
HFD1_k127_7576425_8 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000002035 143.0
HFD1_k127_7576425_9 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000001244 98.0
HFD1_k127_7582485_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 418.0
HFD1_k127_7582485_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007254 289.0
HFD1_k127_7582485_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009322 282.0
HFD1_k127_7582485_3 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000002598 251.0
HFD1_k127_7582485_4 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000005655 250.0
HFD1_k127_7582485_5 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000008401 246.0
HFD1_k127_7582485_6 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000003536 225.0
HFD1_k127_7582485_7 COG1233 Phytoene dehydrogenase and related - - - 0.00000000000000000000000000000000000000000000000000000001252 217.0
HFD1_k127_7582485_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000001208 93.0
HFD1_k127_7614055_0 metal-dependent hydrolase with the TIM-barrel fold - - - 1.151e-278 869.0
HFD1_k127_7614055_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.063e-209 671.0
HFD1_k127_7614055_10 peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004116 278.0
HFD1_k127_7614055_11 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005001 254.0
HFD1_k127_7614055_12 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000003797 222.0
HFD1_k127_7614055_13 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000001265 216.0
HFD1_k127_7614055_14 - K09932 - - 0.0000000000000000000000000000000000000001604 156.0
HFD1_k127_7614055_15 Cyclase dehydrase K14670 - - 0.00000000000000000000000000000000003962 139.0
HFD1_k127_7614055_16 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000001781 129.0
HFD1_k127_7614055_17 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000006385 128.0
HFD1_k127_7614055_18 histidine kinase - - - 0.000000000000000000000007408 115.0
HFD1_k127_7614055_19 Transcriptional regulator PadR-like family - - - 0.0000000000001206 78.0
HFD1_k127_7614055_2 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 541.0
HFD1_k127_7614055_20 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000001109 71.0
HFD1_k127_7614055_21 NAD FAD-binding protein K06954 - - 0.00000000001591 71.0
HFD1_k127_7614055_22 - - - - 0.000003484 53.0
HFD1_k127_7614055_23 - - - - 0.0001065 48.0
HFD1_k127_7614055_3 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 453.0
HFD1_k127_7614055_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K05551 - 2.3.1.235,2.3.1.260 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 431.0
HFD1_k127_7614055_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 310.0
HFD1_k127_7614055_6 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
HFD1_k127_7614055_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 300.0
HFD1_k127_7614055_8 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001676 284.0
HFD1_k127_7614055_9 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005626 275.0
HFD1_k127_7617586_0 PFAM UBA THIF-type NAD FAD binding protein K03148 - 2.7.7.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 312.0
HFD1_k127_7617586_1 biosynthesis protein ThiH K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000599 232.0
HFD1_k127_7617586_2 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000008923 184.0
HFD1_k127_7663959_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 5.335e-199 641.0
HFD1_k127_7663959_1 plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 537.0
HFD1_k127_7663959_10 PFAM Tetratricopeptide repeat - - - 0.000000004337 66.0
HFD1_k127_7663959_11 Class III cytochrome C family - - - 0.00002741 48.0
HFD1_k127_7663959_2 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 526.0
HFD1_k127_7663959_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 374.0
HFD1_k127_7663959_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 340.0
HFD1_k127_7663959_5 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 344.0
HFD1_k127_7663959_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000006996 235.0
HFD1_k127_7663959_7 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000001546 198.0
HFD1_k127_7663959_8 O-methyltransferase activity K00588 - 2.1.1.104 0.00000000000000000000000000000000006213 141.0
HFD1_k127_7663959_9 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000001003 128.0
HFD1_k127_7686844_0 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 300.0
HFD1_k127_7686844_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005316 281.0
HFD1_k127_7686844_2 Peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007259 250.0
HFD1_k127_7686844_3 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000699 142.0
HFD1_k127_7686844_4 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000007638 139.0
HFD1_k127_7686844_5 PFAM Cobalt transport protein K02008 - - 0.00000000000000000000000000001133 128.0
HFD1_k127_7686844_6 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000002131 116.0
HFD1_k127_7686844_7 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000968 82.0
HFD1_k127_7686844_8 Phosphate-starvation-inducible E - - - 0.00000000003844 70.0
HFD1_k127_7686844_9 Predicted RNA-binding protein - - - 0.0000000001744 63.0
HFD1_k127_7718901_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 478.0
HFD1_k127_7718901_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000003489 166.0
HFD1_k127_7718901_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000002428 121.0
HFD1_k127_7718901_3 Sodium/calcium exchanger protein K07301 - - 0.000025 48.0
HFD1_k127_7727366_0 Elongator protein 3, MiaB family, Radical SAM - - - 6.869e-196 635.0
HFD1_k127_7727366_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 412.0
HFD1_k127_7727366_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 352.0
HFD1_k127_7727366_3 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 296.0
HFD1_k127_7727366_4 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006028 285.0
HFD1_k127_7727366_5 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006798 230.0
HFD1_k127_7727366_6 EamA-like transporter family - - - 0.000000000000000000000001081 108.0
HFD1_k127_7727366_7 Tetratricopeptide repeat - - - 0.000000000000000001688 95.0
HFD1_k127_7727366_8 Lipid A 3-O-deacylase (PagL) - - - 0.00000001168 65.0
HFD1_k127_7732192_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 366.0
HFD1_k127_7732192_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 361.0
HFD1_k127_7732192_2 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 346.0
HFD1_k127_7732192_3 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000001075 207.0
HFD1_k127_7732192_4 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000001414 128.0
HFD1_k127_7732192_5 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000002035 115.0
HFD1_k127_7732192_6 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000002234 120.0
HFD1_k127_7732192_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000004469 108.0
HFD1_k127_7748241_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 498.0
HFD1_k127_7748241_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 473.0
HFD1_k127_7748241_10 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000001343 183.0
HFD1_k127_7748241_11 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000002629 177.0
HFD1_k127_7748241_12 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000007431 131.0
HFD1_k127_7748241_13 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000002495 118.0
HFD1_k127_7748241_15 Protein of unknown function (DUF3467) - - - 0.00000000000000000009652 93.0
HFD1_k127_7748241_16 Trypsin - - - 0.00000000000000001201 93.0
HFD1_k127_7748241_17 Belongs to the HesB IscA family - - - 0.000007932 53.0
HFD1_k127_7748241_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 356.0
HFD1_k127_7748241_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 341.0
HFD1_k127_7748241_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 331.0
HFD1_k127_7748241_5 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 333.0
HFD1_k127_7748241_6 Protein of unknown function (DUF401) K09133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 328.0
HFD1_k127_7748241_7 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 292.0
HFD1_k127_7748241_8 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000003821 235.0
HFD1_k127_7748241_9 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000378 190.0
HFD1_k127_7750604_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1356.0
HFD1_k127_7750604_1 helicase superfamily c-terminal domain K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 535.0
HFD1_k127_7750604_10 Surface antigen - - - 0.0000001183 56.0
HFD1_k127_7750604_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 378.0
HFD1_k127_7750604_3 galactose-1-phosphate K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 337.0
HFD1_k127_7750604_4 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 288.0
HFD1_k127_7750604_5 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002198 244.0
HFD1_k127_7750604_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000001795 225.0
HFD1_k127_7750604_7 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000009847 220.0
HFD1_k127_7750604_8 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000000000000000000000000000000000000000000000000000006043 210.0
HFD1_k127_7750604_9 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000007265 130.0
HFD1_k127_7773504_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000001173 188.0
HFD1_k127_7773504_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000006092 142.0
HFD1_k127_7773504_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.000000000000008782 74.0
HFD1_k127_7773504_3 Sulfur reduction protein DsrE - - - 0.0000000001087 73.0
HFD1_k127_7773504_4 DsrE/DsrF-like family - - - 0.00000002459 60.0
HFD1_k127_7829518_0 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 506.0
HFD1_k127_7829518_1 phosphate ion binding K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 400.0
HFD1_k127_7829518_10 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005385 267.0
HFD1_k127_7829518_11 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001384 266.0
HFD1_k127_7829518_12 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 261.0
HFD1_k127_7829518_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 250.0
HFD1_k127_7829518_14 PFAM Stage II sporulation K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000004175 245.0
HFD1_k127_7829518_15 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001006 237.0
HFD1_k127_7829518_16 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000006071 223.0
HFD1_k127_7829518_17 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000001965 221.0
HFD1_k127_7829518_18 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000969 224.0
HFD1_k127_7829518_19 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000009024 180.0
HFD1_k127_7829518_2 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 398.0
HFD1_k127_7829518_20 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000002153 156.0
HFD1_k127_7829518_21 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000521 156.0
HFD1_k127_7829518_22 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000002129 137.0
HFD1_k127_7829518_23 Protein of unknown function (DUF2905) - - - 0.00000000000000000008906 91.0
HFD1_k127_7829518_24 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000925 87.0
HFD1_k127_7829518_25 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000002759 92.0
HFD1_k127_7829518_26 HEPN domain - - - 0.0000000265 61.0
HFD1_k127_7829518_28 Lipoprotein - - - 0.0003097 51.0
HFD1_k127_7829518_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 370.0
HFD1_k127_7829518_4 PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 361.0
HFD1_k127_7829518_5 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 366.0
HFD1_k127_7829518_6 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 351.0
HFD1_k127_7829518_7 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 324.0
HFD1_k127_7829518_8 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 313.0
HFD1_k127_7829518_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 306.0
HFD1_k127_7871605_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 338.0
HFD1_k127_7871605_1 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 328.0
HFD1_k127_7871605_2 Thiamine biosynthesis protein - - - 0.0000000000000000002098 89.0
HFD1_k127_7925063_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1283.0
HFD1_k127_7925063_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 403.0
HFD1_k127_7925063_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000000000005321 211.0
HFD1_k127_7925063_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000007645 196.0
HFD1_k127_7925063_4 5'-nucleotidase - - - 0.0000000000000000000000000000000000005754 156.0
HFD1_k127_7925063_5 PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000001397 64.0
HFD1_k127_7970771_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 405.0
HFD1_k127_7970771_1 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000001809 109.0
HFD1_k127_7970771_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00004157 53.0
HFD1_k127_7972759_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.034e-280 872.0
HFD1_k127_7972759_1 Dehydratase family K01687 - 4.2.1.9 6.761e-250 782.0
HFD1_k127_7972759_10 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 392.0
HFD1_k127_7972759_11 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 346.0
HFD1_k127_7972759_12 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 325.0
HFD1_k127_7972759_13 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 295.0
HFD1_k127_7972759_14 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 308.0
HFD1_k127_7972759_15 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000007453 261.0
HFD1_k127_7972759_16 HMGL-like - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003372 254.0
HFD1_k127_7972759_17 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000005954 256.0
HFD1_k127_7972759_18 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001253 254.0
HFD1_k127_7972759_19 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004321 242.0
HFD1_k127_7972759_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.789e-222 697.0
HFD1_k127_7972759_20 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000001222 237.0
HFD1_k127_7972759_21 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
HFD1_k127_7972759_22 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000003207 220.0
HFD1_k127_7972759_23 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000005069 217.0
HFD1_k127_7972759_24 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000004937 188.0
HFD1_k127_7972759_25 negative regulation of translational initiation K05554,K15885 - - 0.00000000000000000000000000000000000000007271 156.0
HFD1_k127_7972759_26 COG0784 FOG CheY-like receiver - - - 0.0000000000000000000000000000000000000001024 168.0
HFD1_k127_7972759_27 Acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000003952 122.0
HFD1_k127_7972759_28 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000002618 103.0
HFD1_k127_7972759_29 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000001297 89.0
HFD1_k127_7972759_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.55e-208 654.0
HFD1_k127_7972759_4 peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 582.0
HFD1_k127_7972759_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 558.0
HFD1_k127_7972759_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 549.0
HFD1_k127_7972759_7 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 535.0
HFD1_k127_7972759_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 512.0
HFD1_k127_7972759_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 464.0
HFD1_k127_8010645_0 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 316.0
HFD1_k127_8010645_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000003556 183.0
HFD1_k127_8010645_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000003736 174.0
HFD1_k127_838774_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 491.0
HFD1_k127_838774_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 417.0
HFD1_k127_838774_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 409.0
HFD1_k127_838774_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000058 145.0
HFD1_k127_875869_0 HELICc2 K03722 - 3.6.4.12 1.232e-240 769.0
HFD1_k127_875869_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.999e-197 622.0
HFD1_k127_875869_10 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 336.0
HFD1_k127_875869_11 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 314.0
HFD1_k127_875869_12 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 306.0
HFD1_k127_875869_13 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 296.0
HFD1_k127_875869_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005659 291.0
HFD1_k127_875869_15 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001396 267.0
HFD1_k127_875869_16 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000004945 223.0
HFD1_k127_875869_17 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000000000000001091 194.0
HFD1_k127_875869_18 LysM domain - - - 0.000000000000000000000000000000000000000000000000000001584 199.0
HFD1_k127_875869_19 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000006816 179.0
HFD1_k127_875869_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 614.0
HFD1_k127_875869_20 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000002225 152.0
HFD1_k127_875869_21 radical SAM domain protein - - - 0.0000000000000000000000000000001757 135.0
HFD1_k127_875869_22 NIL - - - 0.000000000000000000000000000002433 124.0
HFD1_k127_875869_23 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000004665 124.0
HFD1_k127_875869_24 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000006322 113.0
HFD1_k127_875869_25 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000013 86.0
HFD1_k127_875869_26 Psort location CytoplasmicMembrane, score - - - 0.0000000006619 70.0
HFD1_k127_875869_28 Protein of unknown function (DUF3024) - - - 0.0000009533 56.0
HFD1_k127_875869_29 - - - - 0.000001903 55.0
HFD1_k127_875869_3 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 516.0
HFD1_k127_875869_30 Colicin V production protein K03558 - - 0.000003071 58.0
HFD1_k127_875869_31 Serine threonine protein kinase - - - 0.00002168 54.0
HFD1_k127_875869_32 - - - - 0.00004249 47.0
HFD1_k127_875869_33 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) - - - 0.0008049 50.0
HFD1_k127_875869_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 432.0
HFD1_k127_875869_5 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 422.0
HFD1_k127_875869_6 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 418.0
HFD1_k127_875869_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 409.0
HFD1_k127_875869_8 PFAM Transketolase central region K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 401.0
HFD1_k127_875869_9 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 362.0
HFD1_k127_891178_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.092e-204 649.0
HFD1_k127_891178_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 375.0
HFD1_k127_891178_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 320.0
HFD1_k127_891178_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000002938 243.0
HFD1_k127_891178_4 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000001797 240.0
HFD1_k127_891178_5 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000002234 105.0
HFD1_k127_891178_6 diguanylate cyclase - - - 0.00000000001504 66.0
HFD1_k127_922346_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.303e-196 621.0
HFD1_k127_922346_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 597.0
HFD1_k127_922346_10 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 418.0
HFD1_k127_922346_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 430.0
HFD1_k127_922346_12 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 409.0
HFD1_k127_922346_13 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 409.0
HFD1_k127_922346_14 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 396.0
HFD1_k127_922346_15 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 360.0
HFD1_k127_922346_16 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 364.0
HFD1_k127_922346_17 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 345.0
HFD1_k127_922346_18 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 354.0
HFD1_k127_922346_19 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 324.0
HFD1_k127_922346_2 FAD binding domain K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 579.0
HFD1_k127_922346_20 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 325.0
HFD1_k127_922346_21 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 317.0
HFD1_k127_922346_22 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 288.0
HFD1_k127_922346_23 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
HFD1_k127_922346_24 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000003848 220.0
HFD1_k127_922346_25 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000004941 229.0
HFD1_k127_922346_26 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000007435 224.0
HFD1_k127_922346_27 Universal stress protein family K07090 - - 0.000000000000000000000000000000000000000000000000000000001238 213.0
HFD1_k127_922346_28 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000000000000000000000000000006872 207.0
HFD1_k127_922346_29 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000008554 188.0
HFD1_k127_922346_3 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 558.0
HFD1_k127_922346_30 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000001511 192.0
HFD1_k127_922346_31 transmembrane transport - - - 0.0000000000000000000000000000000000000000001392 168.0
HFD1_k127_922346_32 - - - - 0.000000000000000000000000000000000000001442 150.0
HFD1_k127_922346_33 - - - - 0.000000000000000000000000000000000000002444 151.0
HFD1_k127_922346_34 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000001849 154.0
HFD1_k127_922346_36 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000001451 136.0
HFD1_k127_922346_37 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000000000002393 129.0
HFD1_k127_922346_38 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000003103 109.0
HFD1_k127_922346_39 - - - - 0.000000000000000000001534 102.0
HFD1_k127_922346_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 565.0
HFD1_k127_922346_40 HEAT repeats - - - 0.0000000000000004032 92.0
HFD1_k127_922346_41 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000002082 83.0
HFD1_k127_922346_42 metal cluster binding - - - 0.0000000000000167 80.0
HFD1_k127_922346_43 DsrE/DsrF-like family - - - 0.00000000002082 70.0
HFD1_k127_922346_44 dTDP-4-dehydrorhamnose 3,5-epimerase activity - - - 0.0000000000241 70.0
HFD1_k127_922346_45 PFAM Lytic transglycosylase catalytic - - - 0.0000001271 55.0
HFD1_k127_922346_46 Evidence 5 No homology to any previously reported sequences - - - 0.0000002242 58.0
HFD1_k127_922346_5 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 537.0
HFD1_k127_922346_50 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00005652 54.0
HFD1_k127_922346_6 glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 544.0
HFD1_k127_922346_7 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 486.0
HFD1_k127_922346_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 481.0
HFD1_k127_922346_9 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 466.0
HFD1_k127_938359_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002207 295.0
HFD1_k127_938359_1 Belongs to the LTA synthase family - - - 0.000000000000000000000000000000000000000000964 179.0
HFD1_k127_938359_2 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000007267 59.0
HFD1_k127_977947_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 5.876e-230 718.0
HFD1_k127_977947_1 NADH-quinone oxidoreductase K00341 - 1.6.5.3 3.045e-213 679.0
HFD1_k127_977947_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000008365 121.0
HFD1_k127_977947_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336,K05299 - 1.17.1.10,1.6.5.3 1.496e-210 684.0
HFD1_k127_977947_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 584.0
HFD1_k127_977947_4 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 503.0
HFD1_k127_977947_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 480.0
HFD1_k127_977947_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 394.0
HFD1_k127_977947_7 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006153 263.0
HFD1_k127_977947_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000009779 152.0
HFD1_k127_977947_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000002955 137.0
HFD1_k127_981844_0 glucan 1,4-alpha-glucosidase activity - - - 2.625e-251 791.0
HFD1_k127_981844_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 561.0
HFD1_k127_981844_10 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000005403 92.0
HFD1_k127_981844_11 amine dehydrogenase activity K01179,K03333,K12287 - 1.1.3.6,3.2.1.4 0.0000000000000000003999 90.0
HFD1_k127_981844_13 fibronectin type III domain protein - - - 0.0000000000001126 81.0
HFD1_k127_981844_14 fibronectin type III domain protein - - - 0.00000000002167 76.0
HFD1_k127_981844_16 - - - - 0.0000000387 59.0
HFD1_k127_981844_17 regulator of chromosome condensation, RCC1 - - - 0.000005126 59.0
HFD1_k127_981844_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 377.0
HFD1_k127_981844_3 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 367.0
HFD1_k127_981844_4 Pyridine nucleotide-disulphide oxidoreductase K00529,K18227,K18249 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 362.0
HFD1_k127_981844_5 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 364.0
HFD1_k127_981844_6 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 324.0
HFD1_k127_981844_7 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000002512 189.0
HFD1_k127_981844_9 Fibronectin type 3 domain K20276 - - 0.00000000000000000000000000001227 138.0