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Overview

ID MAG01624
Name HFD1_bin.37
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rhizobiales
Family Xanthobacteraceae
Genus Pseudolabrys
Species Pseudolabrys sp035310865
Assembly information
Completeness (%) 77.85
Contamination (%) 0.3
GC content (%) 61.0
N50 (bp) 34,264
Genome size (bp) 2,854,959

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2870

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1007172_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469 - 3.5.2.9 0.0 1824.0
HFD1_k127_1007172_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.558e-210 661.0
HFD1_k127_1007172_10 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 363.0
HFD1_k127_1007172_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 296.0
HFD1_k127_1007172_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004115 285.0
HFD1_k127_1007172_13 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000503 254.0
HFD1_k127_1007172_14 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003899 250.0
HFD1_k127_1007172_15 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000553 230.0
HFD1_k127_1007172_16 transport system small permease component - - - 0.000000000000000000000000000000000000000000000000003701 186.0
HFD1_k127_1007172_17 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000001694 177.0
HFD1_k127_1007172_18 - - - - 0.00000000000000000000000000000000002633 141.0
HFD1_k127_1007172_19 Domain of unknown function (DUF4170) - - - 0.00000000000000000000000000000000858 129.0
HFD1_k127_1007172_2 Belongs to the GARS family K01945 - 6.3.4.13 1.082e-203 640.0
HFD1_k127_1007172_20 TIGRFAM methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000002566 125.0
HFD1_k127_1007172_21 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.00000000000000000000000009897 108.0
HFD1_k127_1007172_22 Ami_2 K00788,K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.5.1.3,3.5.1.28 0.00000000000000000005697 91.0
HFD1_k127_1007172_23 - - - - 0.000000000000000006309 88.0
HFD1_k127_1007172_3 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 4.872e-199 629.0
HFD1_k127_1007172_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 605.0
HFD1_k127_1007172_5 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 505.0
HFD1_k127_1007172_6 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 483.0
HFD1_k127_1007172_7 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 456.0
HFD1_k127_1007172_8 Alpha beta hydrolase K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 443.0
HFD1_k127_1007172_9 S4 RNA-binding domain K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 366.0
HFD1_k127_1058446_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0 1143.0
HFD1_k127_1058446_1 Transglycosylase SLT domain K08309 - - 7.164e-217 696.0
HFD1_k127_1058446_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 314.0
HFD1_k127_1058446_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 304.0
HFD1_k127_1058446_12 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000003904 257.0
HFD1_k127_1058446_13 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001672 241.0
HFD1_k127_1058446_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000289 229.0
HFD1_k127_1058446_15 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000059 213.0
HFD1_k127_1058446_16 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000006399 198.0
HFD1_k127_1058446_17 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000007598 195.0
HFD1_k127_1058446_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 502.0
HFD1_k127_1058446_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 437.0
HFD1_k127_1058446_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 384.0
HFD1_k127_1058446_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 390.0
HFD1_k127_1058446_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 369.0
HFD1_k127_1058446_7 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 349.0
HFD1_k127_1058446_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 345.0
HFD1_k127_1058446_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 326.0
HFD1_k127_1087111_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 608.0
HFD1_k127_1087111_1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 587.0
HFD1_k127_1087111_10 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 442.0
HFD1_k127_1087111_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 421.0
HFD1_k127_1087111_12 Transcriptional regulatory protein, C terminal K07657 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 406.0
HFD1_k127_1087111_13 Phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 419.0
HFD1_k127_1087111_14 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 389.0
HFD1_k127_1087111_15 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 361.0
HFD1_k127_1087111_16 oxidoreductase FAD NAD(P)-binding domain protein K18069,K21324,K21607 - 1.1.1.404 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 364.0
HFD1_k127_1087111_17 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 293.0
HFD1_k127_1087111_18 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 286.0
HFD1_k127_1087111_19 Bacterial regulatory helix-turn-helix protein, lysR family K02623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002517 267.0
HFD1_k127_1087111_2 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 571.0
HFD1_k127_1087111_20 PFAM lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003134 244.0
HFD1_k127_1087111_21 GcrA cell cycle regulator K13583 - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 233.0
HFD1_k127_1087111_22 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000003587 226.0
HFD1_k127_1087111_23 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000000009413 195.0
HFD1_k127_1087111_24 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000001183 149.0
HFD1_k127_1087111_25 Cytochrome c - - - 0.00000000000000000001768 93.0
HFD1_k127_1087111_26 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000149 72.0
HFD1_k127_1087111_27 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000008787 72.0
HFD1_k127_1087111_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 545.0
HFD1_k127_1087111_4 OpgC protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 509.0
HFD1_k127_1087111_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 501.0
HFD1_k127_1087111_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 481.0
HFD1_k127_1087111_7 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 458.0
HFD1_k127_1087111_8 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 460.0
HFD1_k127_1087111_9 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 446.0
HFD1_k127_1102343_0 membrane - - - 1.972e-303 942.0
HFD1_k127_1102343_1 Isocitrate/isopropylmalate dehydrogenase K00052 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 582.0
HFD1_k127_1102343_10 motor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 421.0
HFD1_k127_1102343_11 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 412.0
HFD1_k127_1102343_12 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 373.0
HFD1_k127_1102343_13 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 371.0
HFD1_k127_1102343_14 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 336.0
HFD1_k127_1102343_15 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 314.0
HFD1_k127_1102343_16 phosphatidylethanolamine N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 313.0
HFD1_k127_1102343_17 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 308.0
HFD1_k127_1102343_18 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 298.0
HFD1_k127_1102343_19 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 320.0
HFD1_k127_1102343_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 595.0
HFD1_k127_1102343_20 Protein of unknown function (DUF1134) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 295.0
HFD1_k127_1102343_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 287.0
HFD1_k127_1102343_22 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001057 278.0
HFD1_k127_1102343_23 Histidine phosphotransferase C-terminal domain K13588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002076 278.0
HFD1_k127_1102343_24 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004755 282.0
HFD1_k127_1102343_25 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002282 261.0
HFD1_k127_1102343_26 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000003268 269.0
HFD1_k127_1102343_27 Inositol monophosphatase family K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000002791 256.0
HFD1_k127_1102343_28 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003195 258.0
HFD1_k127_1102343_29 Flavodoxin-like fold K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000005857 236.0
HFD1_k127_1102343_3 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 556.0
HFD1_k127_1102343_30 TRAP transporter, solute receptor (TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000004356 229.0
HFD1_k127_1102343_31 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000002785 218.0
HFD1_k127_1102343_32 Sigma-54 interaction domain K10943 - - 0.00000000000000000000000000000000000000000000000000000000000008875 215.0
HFD1_k127_1102343_33 - - - - 0.00000000000000000000000000000000000000000000000000000001482 202.0
HFD1_k127_1102343_34 Flagellar FliJ protein - - - 0.00000000000000000000000000000000000000000000000000002234 190.0
HFD1_k127_1102343_35 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000004025 187.0
HFD1_k127_1102343_36 Protein of unknown function (DUF1153) - - - 0.00000000000000000000000000000000000000000000000002462 179.0
HFD1_k127_1102343_37 - - - - 0.000000000000000000000000000000000000000000002539 179.0
HFD1_k127_1102343_38 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000007169 162.0
HFD1_k127_1102343_39 Protein of unknown function (DUF952) - - - 0.0000000000000000000000000000000000000004978 156.0
HFD1_k127_1102343_4 Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 523.0
HFD1_k127_1102343_40 Flagellar hook-length control protein FliK K10565 - - 0.000000000000000000000000000000000000001367 153.0
HFD1_k127_1102343_41 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.00000000000000000000000000000000000001026 146.0
HFD1_k127_1102343_42 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000203 128.0
HFD1_k127_1102343_43 YHS domain protein - - - 0.0000000000000000000000000000002557 130.0
HFD1_k127_1102343_44 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.000000000000000000000000000007044 120.0
HFD1_k127_1102343_45 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.000000000000000000000004299 104.0
HFD1_k127_1102343_46 Histidine kinase K03407 - 2.7.13.3 0.0000000000000000000005569 99.0
HFD1_k127_1102343_47 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000007539 88.0
HFD1_k127_1102343_48 - - - - 0.000000000000000001436 92.0
HFD1_k127_1102343_49 DoxX K15977 - - 0.0000000000000000603 87.0
HFD1_k127_1102343_5 NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 508.0
HFD1_k127_1102343_50 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000006417 81.0
HFD1_k127_1102343_51 protein conserved in bacteria - - - 0.00000000000000006696 85.0
HFD1_k127_1102343_52 cheY-homologous receiver domain - - - 0.0000000000000002597 89.0
HFD1_k127_1102343_53 cheY-homologous receiver domain K03413 - - 0.00000000000002745 76.0
HFD1_k127_1102343_54 YCII-related domain K09780 - - 0.00000000002973 67.0
HFD1_k127_1102343_55 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000005365 65.0
HFD1_k127_1102343_56 - - - - 0.000000007498 62.0
HFD1_k127_1102343_57 Anti-sigma-K factor rskA - - - 0.0000000203 56.0
HFD1_k127_1102343_58 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.00006493 48.0
HFD1_k127_1102343_6 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 490.0
HFD1_k127_1102343_7 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 462.0
HFD1_k127_1102343_8 Transcriptional regulatory protein, C terminal K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 451.0
HFD1_k127_1102343_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 428.0
HFD1_k127_111453_0 FAD linked oxidases, C-terminal domain - - - 0.0 1386.0
HFD1_k127_111453_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 5.104e-204 649.0
HFD1_k127_111453_10 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 455.0
HFD1_k127_111453_11 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 440.0
HFD1_k127_111453_12 Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 427.0
HFD1_k127_111453_13 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 404.0
HFD1_k127_111453_14 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 384.0
HFD1_k127_111453_15 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 382.0
HFD1_k127_111453_16 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 350.0
HFD1_k127_111453_17 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 314.0
HFD1_k127_111453_18 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 301.0
HFD1_k127_111453_19 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001461 292.0
HFD1_k127_111453_2 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 596.0
HFD1_k127_111453_20 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000004285 216.0
HFD1_k127_111453_21 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.00000000000000000000000000000000000000000000000000000003133 203.0
HFD1_k127_111453_22 - - - - 0.00000000000000000000000000000000000000000000000000007941 196.0
HFD1_k127_111453_23 Transcriptional regulator K05799 - - 0.000000000000000000000000000000000000000005543 164.0
HFD1_k127_111453_24 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase K05921,K18336 - 4.1.1.68 0.0000000000000000000000000000000000000128 146.0
HFD1_k127_111453_25 Domain of unknown function (DUF4337) - - - 0.000000000000000005425 85.0
HFD1_k127_111453_26 Domain of unknown function (DUF4337) - - - 0.00000000001179 68.0
HFD1_k127_111453_27 - - - - 0.000000002118 62.0
HFD1_k127_111453_28 Domain of unknown function (DUF4337) - - - 0.000003911 50.0
HFD1_k127_111453_3 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 567.0
HFD1_k127_111453_4 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 550.0
HFD1_k127_111453_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 508.0
HFD1_k127_111453_6 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 507.0
HFD1_k127_111453_7 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 474.0
HFD1_k127_111453_8 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 471.0
HFD1_k127_111453_9 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 482.0
HFD1_k127_1118352_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 518.0
HFD1_k127_1118352_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 502.0
HFD1_k127_1118352_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 351.0
HFD1_k127_1118352_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 317.0
HFD1_k127_1118352_4 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K01826 - 5.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000007125 236.0
HFD1_k127_1118352_5 phosphohistidine phosphatase, SixA - - - 0.0000000000000000000000000000000000000000000000000001547 192.0
HFD1_k127_1118352_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000002979 171.0
HFD1_k127_1133391_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 2398.0
HFD1_k127_1133391_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.124e-317 983.0
HFD1_k127_1133391_10 Major facilitator superfamily - - - 3.614e-228 715.0
HFD1_k127_1133391_11 Glycosyl transferase family group 2 K03669 - - 4.183e-218 695.0
HFD1_k127_1133391_12 Receptor family ligand binding region K01999 - - 1.905e-216 676.0
HFD1_k127_1133391_13 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 2.685e-211 665.0
HFD1_k127_1133391_14 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 2.33e-204 640.0
HFD1_k127_1133391_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 621.0
HFD1_k127_1133391_16 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 588.0
HFD1_k127_1133391_17 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 512.0
HFD1_k127_1133391_18 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 503.0
HFD1_k127_1133391_19 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 482.0
HFD1_k127_1133391_2 Proton-conducting membrane transporter - - - 1.837e-317 983.0
HFD1_k127_1133391_20 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 479.0
HFD1_k127_1133391_21 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 460.0
HFD1_k127_1133391_22 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 450.0
HFD1_k127_1133391_23 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 426.0
HFD1_k127_1133391_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 438.0
HFD1_k127_1133391_25 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 423.0
HFD1_k127_1133391_26 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 417.0
HFD1_k127_1133391_27 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 404.0
HFD1_k127_1133391_28 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 389.0
HFD1_k127_1133391_29 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 379.0
HFD1_k127_1133391_3 MMPL family K07003 - - 9.134e-315 982.0
HFD1_k127_1133391_30 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 362.0
HFD1_k127_1133391_31 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 346.0
HFD1_k127_1133391_32 Squalene/phytoene synthase K21678,K21679 - 2.5.1.103,4.2.3.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 342.0
HFD1_k127_1133391_33 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 341.0
HFD1_k127_1133391_34 Squalene/phytoene synthase K02291,K21678 - 2.5.1.103,2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 321.0
HFD1_k127_1133391_35 COG1985 Pyrimidine reductase, riboflavin biosynthesis K00082 - 1.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 314.0
HFD1_k127_1133391_36 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 297.0
HFD1_k127_1133391_37 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 301.0
HFD1_k127_1133391_38 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 292.0
HFD1_k127_1133391_39 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000003053 235.0
HFD1_k127_1133391_4 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 6.896e-307 955.0
HFD1_k127_1133391_40 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000008284 226.0
HFD1_k127_1133391_41 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000978 226.0
HFD1_k127_1133391_42 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000002056 216.0
HFD1_k127_1133391_43 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000000000003815 221.0
HFD1_k127_1133391_44 Creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000002615 215.0
HFD1_k127_1133391_45 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.000000000000000000000000000000000000000000000000000000001302 208.0
HFD1_k127_1133391_46 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000000000001374 173.0
HFD1_k127_1133391_47 - - - - 0.0000000000000000000000000000000000126 145.0
HFD1_k127_1133391_48 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000001938 125.0
HFD1_k127_1133391_49 Cytochrome c - - - 0.000000000000000000000000000004345 126.0
HFD1_k127_1133391_5 Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 1.27e-303 954.0
HFD1_k127_1133391_50 DNA repair - - - 0.000000000000000000000000000004503 130.0
HFD1_k127_1133391_51 - - - - 0.00000000000000000000008403 104.0
HFD1_k127_1133391_52 LTXXQ motif family protein - - - 0.000000000000000001069 98.0
HFD1_k127_1133391_53 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000005903 91.0
HFD1_k127_1133391_54 - - - - 0.00000001675 61.0
HFD1_k127_1133391_55 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0001164 46.0
HFD1_k127_1133391_6 Proton-conducting membrane transporter K12141 - - 1.246e-261 811.0
HFD1_k127_1133391_7 Involved in beta-(1-- 2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 1.31e-246 773.0
HFD1_k127_1133391_8 FAD dependent oxidoreductase - - - 2.629e-246 769.0
HFD1_k127_1133391_9 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 3.909e-233 734.0
HFD1_k127_1209460_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1182.0
HFD1_k127_1209460_1 Heat shock 70 kDa protein K04043 - - 0.0 1106.0
HFD1_k127_1209460_10 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 441.0
HFD1_k127_1209460_11 LppC putative lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 439.0
HFD1_k127_1209460_12 ATPases associated with a variety of cellular activities K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 429.0
HFD1_k127_1209460_13 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 425.0
HFD1_k127_1209460_14 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 406.0
HFD1_k127_1209460_15 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 402.0
HFD1_k127_1209460_16 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 379.0
HFD1_k127_1209460_17 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 387.0
HFD1_k127_1209460_18 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 368.0
HFD1_k127_1209460_19 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 366.0
HFD1_k127_1209460_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.078e-213 674.0
HFD1_k127_1209460_20 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 349.0
HFD1_k127_1209460_21 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 345.0
HFD1_k127_1209460_22 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 367.0
HFD1_k127_1209460_23 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 346.0
HFD1_k127_1209460_24 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 332.0
HFD1_k127_1209460_25 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 324.0
HFD1_k127_1209460_26 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 317.0
HFD1_k127_1209460_27 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 314.0
HFD1_k127_1209460_28 Ribosomal RNA adenine dimethylase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 290.0
HFD1_k127_1209460_29 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003397 271.0
HFD1_k127_1209460_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 9.645e-201 630.0
HFD1_k127_1209460_30 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000438 267.0
HFD1_k127_1209460_31 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000399 245.0
HFD1_k127_1209460_32 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001296 242.0
HFD1_k127_1209460_33 PTS IIA-like nitrogen-regulatory protein PtsN K02806 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 - 0.00000000000000000000000000000000000000000000000000000000000000000000154 239.0
HFD1_k127_1209460_34 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000000000000000000000000000000000000000006286 224.0
HFD1_k127_1209460_35 OstA-like protein K09774 - - 0.000000000000000000000000000000000000000000000000000000000003209 214.0
HFD1_k127_1209460_36 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000002162 212.0
HFD1_k127_1209460_37 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000004969 203.0
HFD1_k127_1209460_38 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000000000000000000000000000000007609 205.0
HFD1_k127_1209460_39 - - - - 0.0000000000000000000000000000000000000000000000000001009 200.0
HFD1_k127_1209460_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 602.0
HFD1_k127_1209460_40 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000000000000000003166 178.0
HFD1_k127_1209460_41 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000001122 150.0
HFD1_k127_1209460_42 Protein of unknown function (DUF1150) - - - 0.00000000000000000000000000000000008864 134.0
HFD1_k127_1209460_43 GIY-YIG catalytic domain - - - 0.000000000000000000000000000000002115 130.0
HFD1_k127_1209460_44 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000002156 126.0
HFD1_k127_1209460_45 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000006822 134.0
HFD1_k127_1209460_46 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000001973 123.0
HFD1_k127_1209460_47 PAS fold - - - 0.00000007674 53.0
HFD1_k127_1209460_48 methyl-accepting chemotaxis protein - - - 0.0000002512 58.0
HFD1_k127_1209460_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 601.0
HFD1_k127_1209460_50 GIY-YIG catalytic domain - - - 0.0009642 46.0
HFD1_k127_1209460_51 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0009972 45.0
HFD1_k127_1209460_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 571.0
HFD1_k127_1209460_7 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 564.0
HFD1_k127_1209460_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 554.0
HFD1_k127_1209460_9 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 451.0
HFD1_k127_1224298_0 DDE superfamily endonuclease - - - 1.977e-229 716.0
HFD1_k127_1224298_1 Putative transposase of IS4/5 family (DUF4096) K07492 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002271 240.0
HFD1_k127_1224298_2 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000002071 176.0
HFD1_k127_1224298_3 DDE superfamily endonuclease - - - 0.000000001543 62.0
HFD1_k127_1224298_4 - - - - 0.00008456 46.0
HFD1_k127_1258136_0 E1 component K00164 - 1.2.4.2 0.0 1669.0
HFD1_k127_1258136_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1095.0
HFD1_k127_1258136_10 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 569.0
HFD1_k127_1258136_11 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 556.0
HFD1_k127_1258136_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 537.0
HFD1_k127_1258136_13 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 475.0
HFD1_k127_1258136_14 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 437.0
HFD1_k127_1258136_15 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 441.0
HFD1_k127_1258136_16 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 411.0
HFD1_k127_1258136_17 Protein conserved in bacteria K09798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 317.0
HFD1_k127_1258136_18 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 309.0
HFD1_k127_1258136_19 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004728 261.0
HFD1_k127_1258136_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.711e-296 916.0
HFD1_k127_1258136_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002318 262.0
HFD1_k127_1258136_21 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002548 262.0
HFD1_k127_1258136_22 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001661 255.0
HFD1_k127_1258136_23 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005483 241.0
HFD1_k127_1258136_24 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000006656 201.0
HFD1_k127_1258136_25 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.0000000000000000000000000000000000000000000000000002033 189.0
HFD1_k127_1258136_26 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000004368 186.0
HFD1_k127_1258136_27 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000007227 152.0
HFD1_k127_1258136_28 Natural resistance-associated macrophage protein - - - 0.000000000001779 67.0
HFD1_k127_1258136_29 Divergent polysaccharide deacetylase K09798 - - 0.0000000001068 70.0
HFD1_k127_1258136_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.799e-278 876.0
HFD1_k127_1258136_31 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000002983 57.0
HFD1_k127_1258136_32 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0003772 49.0
HFD1_k127_1258136_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.346e-274 846.0
HFD1_k127_1258136_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 1.171e-231 724.0
HFD1_k127_1258136_6 tail specific protease K03797 - 3.4.21.102 3.29e-228 715.0
HFD1_k127_1258136_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 1.254e-197 627.0
HFD1_k127_1258136_8 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 614.0
HFD1_k127_1258136_9 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 577.0
HFD1_k127_1377140_0 Belongs to the peptidase M17 family K01255 - 3.4.11.1 1.358e-200 636.0
HFD1_k127_1377140_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 474.0
HFD1_k127_1377140_2 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 410.0
HFD1_k127_1377140_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000001659 229.0
HFD1_k127_1377140_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000652 188.0
HFD1_k127_1492949_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2387.0
HFD1_k127_1492949_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1428.0
HFD1_k127_1492949_10 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 509.0
HFD1_k127_1492949_11 Isocitrate/isopropylmalate dehydrogenase K00031,K00052,K07246 - 1.1.1.42,1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 476.0
HFD1_k127_1492949_12 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 464.0
HFD1_k127_1492949_13 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 452.0
HFD1_k127_1492949_14 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 427.0
HFD1_k127_1492949_15 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 385.0
HFD1_k127_1492949_16 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 377.0
HFD1_k127_1492949_17 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 350.0
HFD1_k127_1492949_18 COG2116 Formate nitrite family of transporters K21990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 347.0
HFD1_k127_1492949_19 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 338.0
HFD1_k127_1492949_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1144.0
HFD1_k127_1492949_20 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 298.0
HFD1_k127_1492949_21 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000136 287.0
HFD1_k127_1492949_22 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004443 278.0
HFD1_k127_1492949_23 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001105 279.0
HFD1_k127_1492949_24 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000007948 234.0
HFD1_k127_1492949_25 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001595 234.0
HFD1_k127_1492949_26 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000005277 233.0
HFD1_k127_1492949_27 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000115 228.0
HFD1_k127_1492949_28 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001347 226.0
HFD1_k127_1492949_29 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000008438 223.0
HFD1_k127_1492949_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0 1071.0
HFD1_k127_1492949_30 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000004979 214.0
HFD1_k127_1492949_31 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001021 210.0
HFD1_k127_1492949_32 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000002556 204.0
HFD1_k127_1492949_33 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000392 203.0
HFD1_k127_1492949_34 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000007255 170.0
HFD1_k127_1492949_35 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000619 172.0
HFD1_k127_1492949_36 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001374 164.0
HFD1_k127_1492949_37 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000004473 163.0
HFD1_k127_1492949_38 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001953 154.0
HFD1_k127_1492949_39 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001384 139.0
HFD1_k127_1492949_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.381e-254 787.0
HFD1_k127_1492949_40 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000001095 136.0
HFD1_k127_1492949_41 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000007086 98.0
HFD1_k127_1492949_42 ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000001383 95.0
HFD1_k127_1492949_43 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000005036 56.0
HFD1_k127_1492949_5 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.936e-243 753.0
HFD1_k127_1492949_6 AAA C-terminal domain K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 3.64e-237 738.0
HFD1_k127_1492949_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 1.403e-208 649.0
HFD1_k127_1492949_8 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 1.099e-207 654.0
HFD1_k127_1492949_9 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 8.787e-196 615.0
HFD1_k127_1525767_0 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 557.0
HFD1_k127_1525767_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 431.0
HFD1_k127_1525767_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 333.0
HFD1_k127_1525767_3 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002538 272.0
HFD1_k127_1525767_4 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000000000000008417 188.0
HFD1_k127_1525767_5 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000007946 168.0
HFD1_k127_1525767_6 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.0000000009614 68.0
HFD1_k127_1577665_0 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 551.0
HFD1_k127_1577665_1 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 533.0
HFD1_k127_1577665_10 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000001758 177.0
HFD1_k127_1577665_11 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000002984 149.0
HFD1_k127_1577665_12 - - - - 0.0000000000704 65.0
HFD1_k127_1577665_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 499.0
HFD1_k127_1577665_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 406.0
HFD1_k127_1577665_4 outer membrane protein and related peptidoglycan-associated (Lipo)proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 402.0
HFD1_k127_1577665_5 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 361.0
HFD1_k127_1577665_6 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 352.0
HFD1_k127_1577665_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 337.0
HFD1_k127_1577665_8 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 316.0
HFD1_k127_1577665_9 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 310.0
HFD1_k127_1682465_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K21566 - - 0.0000000000000000000001003 113.0
HFD1_k127_1682465_1 Haem-degrading - - - 0.0000000000004695 74.0
HFD1_k127_1682465_2 KR domain - - - 0.0000003407 57.0
HFD1_k127_1689145_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 297.0
HFD1_k127_1689145_1 NMT1-like family K02051,K15553 - - 0.000000000000000000000000004404 118.0
HFD1_k127_1696203_0 Nitrate reductase beta subunit K00371 - 1.7.5.1 1.986e-312 960.0
HFD1_k127_1696203_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 501.0
HFD1_k127_1696203_2 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 391.0
HFD1_k127_1696203_3 Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002198 269.0
HFD1_k127_1711358_0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K01784,K03274 - 5.1.3.2,5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 497.0
HFD1_k127_1711358_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 450.0
HFD1_k127_1711358_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 447.0
HFD1_k127_1711358_3 heptosyltransferase K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 372.0
HFD1_k127_1711358_4 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 361.0
HFD1_k127_1711358_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000002749 143.0
HFD1_k127_1746921_0 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 594.0
HFD1_k127_1746921_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K18357 - 1.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000004201 254.0
HFD1_k127_1746921_2 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171,K18358 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000001502 158.0
HFD1_k127_1746921_3 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297,K18359 - 1.18.1.1,1.2.1.58,1.7.1.15 0.000000000000000000000000000000009115 130.0
HFD1_k127_1750900_0 Diguanylate cyclase K13245 - 3.1.4.52 0.0 1525.0
HFD1_k127_1750900_1 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 502.0
HFD1_k127_1750900_10 Protein of unknown function (DUF1465) K13592 - - 0.000000000000000000000000000000000000000000000000000001834 197.0
HFD1_k127_1750900_11 Protein of unknown function (DUF1192) - - - 0.00000000000000005406 82.0
HFD1_k127_1750900_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 500.0
HFD1_k127_1750900_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 463.0
HFD1_k127_1750900_4 Uncharacterized ACR, COG1678 K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 344.0
HFD1_k127_1750900_5 Protein of unknown function (DUF1013) K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
HFD1_k127_1750900_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 317.0
HFD1_k127_1750900_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001443 256.0
HFD1_k127_1750900_8 Disulphide bond corrector protein DsbC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 251.0
HFD1_k127_1750900_9 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000001776 229.0
HFD1_k127_1829448_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K02229 - 1.14.13.83,1.7.7.1 2.072e-265 829.0
HFD1_k127_1829448_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 4.835e-224 706.0
HFD1_k127_1829448_10 Domain of unknown function (DUF1993) - - - 0.000000000000000000000000000000000000000000000000000000000000001852 222.0
HFD1_k127_1829448_11 Class II aldolase K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.00000000000000000000000000000000000000000000000000000001259 207.0
HFD1_k127_1829448_12 Formate/nitrite transporter - - - 0.0000000000000000000000000000000001543 136.0
HFD1_k127_1829448_13 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000002498 132.0
HFD1_k127_1829448_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 532.0
HFD1_k127_1829448_3 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 379.0
HFD1_k127_1829448_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051,K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 338.0
HFD1_k127_1829448_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 287.0
HFD1_k127_1829448_6 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 296.0
HFD1_k127_1829448_7 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009534 282.0
HFD1_k127_1829448_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000686 263.0
HFD1_k127_1829448_9 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001366 249.0
HFD1_k127_1855852_0 M61 glycyl aminopeptidase - - - 6.53e-235 742.0
HFD1_k127_1855852_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000009719 100.0
HFD1_k127_1855852_2 Nitrate ABC transporter substrate-binding protein K02051 - - 0.0000000001793 72.0
HFD1_k127_1858477_0 YcjX-like family, DUF463 K06918 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 346.0
HFD1_k127_1858477_1 Inner membrane component domain - - - 0.00000000000000000000000000000000000000000000000000000000000002649 219.0
HFD1_k127_1858477_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000002434 131.0
HFD1_k127_1908376_0 Hydrolase CocE NonD family K06978 - - 7.009e-267 835.0
HFD1_k127_1908376_1 Hydrolase CocE NonD family K06978 - - 3.812e-233 739.0
HFD1_k127_1908376_10 - - - - 0.000000000006638 69.0
HFD1_k127_1908376_12 Integrase core domain - - - 0.0001025 46.0
HFD1_k127_1908376_2 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 333.0
HFD1_k127_1908376_3 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 314.0
HFD1_k127_1908376_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 302.0
HFD1_k127_1908376_5 Bacterial sugar transferase K03606,K20997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006087 260.0
HFD1_k127_1908376_6 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000003575 227.0
HFD1_k127_1908376_7 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10118,K10237 - - 0.0000000000000000000000000000000000000000000000000005516 198.0
HFD1_k127_1908376_8 carbohydrate transport - - - 0.000000000000000000000000000000000000000003344 173.0
HFD1_k127_1908376_9 Transcriptional regulator - - - 0.000000000000000006946 86.0
HFD1_k127_1916836_0 GtrA-like protein K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 402.0
HFD1_k127_1916836_1 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 311.0
HFD1_k127_1916836_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 307.0
HFD1_k127_1916836_3 NMT1-like family K15576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000332 243.0
HFD1_k127_1916836_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000005166 48.0
HFD1_k127_1969705_0 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004124 270.0
HFD1_k127_1969705_1 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000004919 201.0
HFD1_k127_1969705_2 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000002409 61.0
HFD1_k127_2058942_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1300.0
HFD1_k127_2058942_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1066.0
HFD1_k127_2058942_10 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 562.0
HFD1_k127_2058942_11 PFAM Prokaryotic protein of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 529.0
HFD1_k127_2058942_12 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 469.0
HFD1_k127_2058942_13 COG0451 Nucleoside-diphosphate-sugar epimerases K22025 - 1.1.1.410 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 470.0
HFD1_k127_2058942_14 Transcriptional regulatory protein, C terminal K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 444.0
HFD1_k127_2058942_15 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 449.0
HFD1_k127_2058942_16 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 364.0
HFD1_k127_2058942_17 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 349.0
HFD1_k127_2058942_18 Penicillin-insensitive murein endopeptidase K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 333.0
HFD1_k127_2058942_19 LTXXQ motif family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 336.0
HFD1_k127_2058942_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 3.651e-270 839.0
HFD1_k127_2058942_20 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 316.0
HFD1_k127_2058942_21 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 304.0
HFD1_k127_2058942_22 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 304.0
HFD1_k127_2058942_23 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 293.0
HFD1_k127_2058942_24 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 293.0
HFD1_k127_2058942_25 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003241 278.0
HFD1_k127_2058942_26 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001174 274.0
HFD1_k127_2058942_27 PTS system fructose IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000000000000000000000008272 222.0
HFD1_k127_2058942_28 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000000002008 206.0
HFD1_k127_2058942_29 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000002464 173.0
HFD1_k127_2058942_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 5.606e-263 816.0
HFD1_k127_2058942_30 Yip1 domain - - - 0.000000000000000000000000000000000000000503 157.0
HFD1_k127_2058942_31 HPr Serine kinase C-terminal domain K06023 - - 0.000000000000000000000000000000000000007373 153.0
HFD1_k127_2058942_32 Plasmid stabilization - - - 0.0000000000000000000000000000007633 124.0
HFD1_k127_2058942_33 Transmembrane secretion effector - - - 0.000000000000000000000000000003437 127.0
HFD1_k127_2058942_34 system phosphocarrier protein HPr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - 0.00000000000000000000000000003661 120.0
HFD1_k127_2058942_35 - - - - 0.00000000000000000000000002494 115.0
HFD1_k127_2058942_4 Histidine kinase K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 1.601e-261 817.0
HFD1_k127_2058942_5 GMC oxidoreductase K00108 - 1.1.99.1 1.355e-249 780.0
HFD1_k127_2058942_6 Mo-co oxidoreductase dimerisation domain K17225 - - 2.405e-245 763.0
HFD1_k127_2058942_7 Transporter associated domain K11105 - - 1.08e-233 736.0
HFD1_k127_2058942_8 acyl-CoA dehydrogenase - - - 6.565e-213 666.0
HFD1_k127_2058942_9 Aminotransferase class I and II - - - 3.966e-212 664.0
HFD1_k127_2099874_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1143.0
HFD1_k127_2099874_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1136.0
HFD1_k127_2099874_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 518.0
HFD1_k127_2099874_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 494.0
HFD1_k127_2099874_12 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 449.0
HFD1_k127_2099874_13 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 436.0
HFD1_k127_2099874_14 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 430.0
HFD1_k127_2099874_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 428.0
HFD1_k127_2099874_16 enoyl-CoA hydratase K01692,K05605 - 3.1.2.4,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 404.0
HFD1_k127_2099874_17 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101,K15054 - 1.1.2.3,1.1.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 373.0
HFD1_k127_2099874_18 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 359.0
HFD1_k127_2099874_19 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 293.0
HFD1_k127_2099874_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 5.696e-258 816.0
HFD1_k127_2099874_20 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001524 281.0
HFD1_k127_2099874_21 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006922 270.0
HFD1_k127_2099874_22 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001038 246.0
HFD1_k127_2099874_23 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001169 237.0
HFD1_k127_2099874_24 SmpA / OmlA family - - - 0.000000000000000000000000000000000000000000000000000004137 197.0
HFD1_k127_2099874_25 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000001714 192.0
HFD1_k127_2099874_26 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000000000008499 187.0
HFD1_k127_2099874_27 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000000000000000000000000104 188.0
HFD1_k127_2099874_28 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000003766 170.0
HFD1_k127_2099874_29 - - - - 0.00000000000000000000000000000000000000007289 157.0
HFD1_k127_2099874_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.282e-235 734.0
HFD1_k127_2099874_30 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000002661 158.0
HFD1_k127_2099874_31 Ubiquinol-cytochrome C chaperone K17662 - - 0.000000000000000000000000004741 114.0
HFD1_k127_2099874_4 Sodium/hydrogen exchanger family - - - 6.635e-232 742.0
HFD1_k127_2099874_5 Reductase C-terminal K05297 - 1.18.1.1 1.506e-220 694.0
HFD1_k127_2099874_6 H( )-stimulated, divalent metal cation uptake system K03322 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 - 7.942e-210 659.0
HFD1_k127_2099874_7 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.238e-198 623.0
HFD1_k127_2099874_8 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 568.0
HFD1_k127_2099874_9 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 550.0
HFD1_k127_2116308_0 COG1042 Acyl-CoA synthetase (NDP forming) K09181 - - 1.937e-267 850.0
HFD1_k127_2116308_1 Resolvase, N terminal domain K06400 - - 0.000003052 51.0
HFD1_k127_2116308_2 Glycine zipper - - - 0.0004185 47.0
HFD1_k127_2156559_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0 1083.0
HFD1_k127_2156559_1 NADH-ubiquinone oxidoreductase subunit G, C-terminal K00336 - 1.6.5.3 0.0 1058.0
HFD1_k127_2156559_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 366.0
HFD1_k127_2156559_11 HAD-hyrolase-like K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 346.0
HFD1_k127_2156559_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 324.0
HFD1_k127_2156559_13 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 321.0
HFD1_k127_2156559_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 309.0
HFD1_k127_2156559_15 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005581 280.0
HFD1_k127_2156559_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000005705 240.0
HFD1_k127_2156559_17 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000004951 227.0
HFD1_k127_2156559_18 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000000000000000971 207.0
HFD1_k127_2156559_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000002117 204.0
HFD1_k127_2156559_2 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 9.723e-267 831.0
HFD1_k127_2156559_20 Domain of unknown function (DUF3291) - - - 0.0000000000000000000000000000000000000000000000000003586 189.0
HFD1_k127_2156559_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000006014 171.0
HFD1_k127_2156559_22 Domain of unknown function (DUF3291) - - - 0.00000000000000000000000000000000000000000183 162.0
HFD1_k127_2156559_23 Protein of unknown function (DUF1467) - - - 0.00000000000000000000001213 102.0
HFD1_k127_2156559_24 copper export protein K07245,K14166 - - 0.00000000000000000006551 97.0
HFD1_k127_2156559_3 NADH-ubiquinone oxidoreductase chain 4, amino terminus K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 1.171e-259 806.0
HFD1_k127_2156559_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 2.158e-250 776.0
HFD1_k127_2156559_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 1.2e-240 747.0
HFD1_k127_2156559_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 3.08e-201 640.0
HFD1_k127_2156559_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 568.0
HFD1_k127_2156559_8 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 409.0
HFD1_k127_2156559_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 377.0
HFD1_k127_2242482_0 PFAM Glycoside hydrolase 15-related - - - 1.561e-316 976.0
HFD1_k127_2242482_1 phosphoglycolate phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 368.0
HFD1_k127_2242482_2 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000007888 267.0
HFD1_k127_2378986_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 1.721e-317 978.0
HFD1_k127_2378986_1 Dehydratase family K22186 - 4.2.1.82 2.573e-312 964.0
HFD1_k127_2378986_10 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 495.0
HFD1_k127_2378986_11 Fumarate hydratase (Fumerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 488.0
HFD1_k127_2378986_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 450.0
HFD1_k127_2378986_13 amine oxidase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 441.0
HFD1_k127_2378986_14 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 424.0
HFD1_k127_2378986_15 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 402.0
HFD1_k127_2378986_16 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 394.0
HFD1_k127_2378986_17 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 377.0
HFD1_k127_2378986_18 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 356.0
HFD1_k127_2378986_19 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 344.0
HFD1_k127_2378986_2 4Fe-4S binding domain - - - 6.067e-299 933.0
HFD1_k127_2378986_20 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 342.0
HFD1_k127_2378986_21 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 345.0
HFD1_k127_2378986_22 Fumarase C-terminus K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 308.0
HFD1_k127_2378986_23 Nitroreductase family K19286 - 1.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 308.0
HFD1_k127_2378986_24 Biotin/lipoate A/B protein ligase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 298.0
HFD1_k127_2378986_25 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001005 277.0
HFD1_k127_2378986_26 MoeA domain protein domain I and II - - - 0.00000000000000000000000000000000000000000000000000000000000003679 228.0
HFD1_k127_2378986_27 - - - - 0.000000000000000000000000000000000000000000000000000000000007056 212.0
HFD1_k127_2378986_28 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000000000000000000000000005638 205.0
HFD1_k127_2378986_29 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000001888 187.0
HFD1_k127_2378986_3 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 5.703e-291 904.0
HFD1_k127_2378986_30 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000000000000000003722 180.0
HFD1_k127_2378986_31 succinate dehydrogenase K00246 - - 0.00000000000000000000000000000000004125 138.0
HFD1_k127_2378986_32 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00247 - - 0.0000000000000000000000000000000002438 136.0
HFD1_k127_2378986_33 Protein of unknown function (DUF3306) - - - 0.00000000000000000000000000003124 126.0
HFD1_k127_2378986_34 sulfur carrier activity K04085 - - 0.0000000000000000000001511 101.0
HFD1_k127_2378986_35 - - - - 0.000000000000007102 77.0
HFD1_k127_2378986_36 TIGRFAM formate dehydrogenase region TAT target - - - 0.000000000748 62.0
HFD1_k127_2378986_4 Sugar (and other) transporter - - - 2.197e-260 807.0
HFD1_k127_2378986_5 MoeA C-terminal region (domain IV) K03750,K07219 - 2.10.1.1 1.088e-246 778.0
HFD1_k127_2378986_6 Extracellular solute-binding protein K02027 - - 5.05e-214 671.0
HFD1_k127_2378986_7 WD domain, G-beta repeat K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 587.0
HFD1_k127_2378986_8 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 574.0
HFD1_k127_2378986_9 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 544.0
HFD1_k127_2404676_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13926 - - 0.0 1199.0
HFD1_k127_2404676_1 Amidohydrolase family K01466 - 3.5.2.5 1.453e-236 740.0
HFD1_k127_2404676_10 ATPases associated with a variety of cellular activities K01996,K11958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 306.0
HFD1_k127_2404676_11 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000515 270.0
HFD1_k127_2404676_12 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000001161 248.0
HFD1_k127_2404676_13 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000001215 224.0
HFD1_k127_2404676_14 Resolvase - - - 0.000000000000000000000000000000000000000000000001834 176.0
HFD1_k127_2404676_2 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 2.349e-219 697.0
HFD1_k127_2404676_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 532.0
HFD1_k127_2404676_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 520.0
HFD1_k127_2404676_5 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 414.0
HFD1_k127_2404676_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 391.0
HFD1_k127_2404676_7 Isocitrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 386.0
HFD1_k127_2404676_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 386.0
HFD1_k127_2404676_9 PFAM ABC transporter related K01995,K10822 - 3.6.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 310.0
HFD1_k127_2409032_0 DNA polymerase beta thumb K02347 - - 2.834e-201 642.0
HFD1_k127_2409032_1 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 436.0
HFD1_k127_2409032_2 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 355.0
HFD1_k127_2409032_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004684 233.0
HFD1_k127_2409032_4 Protein of unknown function (DUF3775) - - - 0.000000000000000000000000000000000000000000000000000000000000001871 222.0
HFD1_k127_2409032_5 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000002732 165.0
HFD1_k127_2409032_6 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000000000000006721 151.0
HFD1_k127_2437599_0 Threonine synthase N terminus K01733 GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 1.959e-212 669.0
HFD1_k127_2437599_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 554.0
HFD1_k127_2437599_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 342.0
HFD1_k127_2437599_3 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 291.0
HFD1_k127_2437599_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) K02109 - - 0.00000000000000000000000000000000000000000000000004518 184.0
HFD1_k127_2437599_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000000000000000000009225 183.0
HFD1_k127_2437599_6 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000001595 160.0
HFD1_k127_2437599_7 - - - - 0.0000000000000000000000000000000000000175 153.0
HFD1_k127_2437599_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000007596 136.0
HFD1_k127_2437599_9 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000000000000000000000000000003044 132.0
HFD1_k127_2445023_0 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 465.0
HFD1_k127_2445023_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000001039 173.0
HFD1_k127_2445023_2 Phasin protein - - - 0.000000003965 63.0
HFD1_k127_2515945_0 Transposase for IS481 element - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 418.0
HFD1_k127_2549594_0 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 1.146e-262 835.0
HFD1_k127_2549594_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.319e-250 777.0
HFD1_k127_2549594_10 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 538.0
HFD1_k127_2549594_11 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 522.0
HFD1_k127_2549594_12 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 496.0
HFD1_k127_2549594_13 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 482.0
HFD1_k127_2549594_14 mandelate racemase muconate lactonizing K22209 - 4.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 464.0
HFD1_k127_2549594_15 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 458.0
HFD1_k127_2549594_16 Binding-protein-dependent transport system inner membrane component K11075 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 434.0
HFD1_k127_2549594_17 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 416.0
HFD1_k127_2549594_18 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 420.0
HFD1_k127_2549594_19 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 413.0
HFD1_k127_2549594_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 9.761e-247 773.0
HFD1_k127_2549594_20 Branched-chain amino acid transport system permease K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 414.0
HFD1_k127_2549594_21 Part of the ABC transporter complex potABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 409.0
HFD1_k127_2549594_22 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 389.0
HFD1_k127_2549594_23 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 382.0
HFD1_k127_2549594_24 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 381.0
HFD1_k127_2549594_25 Binding-protein-dependent transport system inner membrane component K11074 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 376.0
HFD1_k127_2549594_26 Branched-chain amino acid transport K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
HFD1_k127_2549594_27 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 376.0
HFD1_k127_2549594_28 Peptidase C26 K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 361.0
HFD1_k127_2549594_29 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 308.0
HFD1_k127_2549594_3 Sugar (and other) transporter - - - 2.665e-246 771.0
HFD1_k127_2549594_30 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 286.0
HFD1_k127_2549594_31 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 284.0
HFD1_k127_2549594_32 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001402 284.0
HFD1_k127_2549594_33 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006264 270.0
HFD1_k127_2549594_34 methionine sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000005776 241.0
HFD1_k127_2549594_35 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000009155 236.0
HFD1_k127_2549594_36 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000006862 171.0
HFD1_k127_2549594_37 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000002116 173.0
HFD1_k127_2549594_38 (Lipo)protein K04754 - - 0.0000000000000000000000000000000000000000002131 169.0
HFD1_k127_2549594_39 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.0000000000000000000000000000000000000000004125 168.0
HFD1_k127_2549594_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.542e-229 719.0
HFD1_k127_2549594_40 Phosphorylase superfamily - - - 0.000000000000000000000000000000000000000005665 169.0
HFD1_k127_2549594_41 MlaC protein - - - 0.00000000000000000000000000000000000001294 152.0
HFD1_k127_2549594_42 TIGRFAM phasin - - - 0.0000000000000000000000000002056 120.0
HFD1_k127_2549594_43 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis - - - 0.000000000000000000000000000843 122.0
HFD1_k127_2549594_44 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02022 - - 0.000000000000000002937 87.0
HFD1_k127_2549594_45 Oxidoreductase FAD-binding domain K00529 - 1.18.1.3 0.0000000000004532 74.0
HFD1_k127_2549594_46 - - - - 0.00000000001109 71.0
HFD1_k127_2549594_47 nuclease - - - 0.00000000007037 64.0
HFD1_k127_2549594_48 Glycosyl transferase family 2 - - - 0.0000000001163 64.0
HFD1_k127_2549594_49 COG0463, glycosyltransferases involved in cell wall biogenesis - - - 0.000000001002 67.0
HFD1_k127_2549594_5 His Kinase A (phosphoacceptor) domain - - - 5.061e-207 676.0
HFD1_k127_2549594_6 AsmA-like C-terminal region K07289 - - 6.499e-201 644.0
HFD1_k127_2549594_7 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 603.0
HFD1_k127_2549594_8 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 587.0
HFD1_k127_2549594_9 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 547.0
HFD1_k127_2689799_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0 1317.0
HFD1_k127_2689799_1 Protein of unknown function - - - 0.0 1069.0
HFD1_k127_2689799_10 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 443.0
HFD1_k127_2689799_11 Aminotransferase class-V K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 417.0
HFD1_k127_2689799_12 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 399.0
HFD1_k127_2689799_13 ATPases associated with a variety of cellular activities K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 390.0
HFD1_k127_2689799_14 Domain of unknown function (DUF892) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006461 259.0
HFD1_k127_2689799_15 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000805 261.0
HFD1_k127_2689799_16 Diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000046 249.0
HFD1_k127_2689799_17 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000059 213.0
HFD1_k127_2689799_18 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000003597 214.0
HFD1_k127_2689799_19 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000004549 198.0
HFD1_k127_2689799_2 Uncharacterized protein family (UPF0051) K09014 - - 2.04e-297 915.0
HFD1_k127_2689799_20 Diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000006073 190.0
HFD1_k127_2689799_21 Pfam:DUF59 - - - 0.00000000000000000000000000000000000000000000001328 177.0
HFD1_k127_2689799_22 Trypsin - - - 0.000000000000000000000003548 105.0
HFD1_k127_2689799_23 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000497 96.0
HFD1_k127_2689799_24 Trypsin - - - 0.0000000000004035 77.0
HFD1_k127_2689799_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 8.183e-253 809.0
HFD1_k127_2689799_4 Cys/Met metabolism PLP-dependent enzyme K11717 - 2.8.1.7,4.4.1.16 1.867e-223 698.0
HFD1_k127_2689799_5 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 8.441e-194 613.0
HFD1_k127_2689799_6 tRNA synthetases class I (W and Y) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 600.0
HFD1_k127_2689799_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 540.0
HFD1_k127_2689799_8 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 512.0
HFD1_k127_2689799_9 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 477.0
HFD1_k127_2750953_0 COG3666 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 357.0
HFD1_k127_2750953_1 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000004609 198.0
HFD1_k127_2750953_2 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.000000000000000004408 87.0
HFD1_k127_2890270_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1245.0
HFD1_k127_2890270_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0 1023.0
HFD1_k127_2890270_10 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 401.0
HFD1_k127_2890270_11 TIGRFAM lytic murein transglycosylase K00786,K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 388.0
HFD1_k127_2890270_12 PFAM Glutathione S-transferase domain K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 373.0
HFD1_k127_2890270_13 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002701 267.0
HFD1_k127_2890270_14 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 262.0
HFD1_k127_2890270_15 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005915 248.0
HFD1_k127_2890270_16 response regulator K11443 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002843 239.0
HFD1_k127_2890270_17 - K09004 - - 0.000000000000000000000000000000000000000000000000005195 185.0
HFD1_k127_2890270_18 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000002754 156.0
HFD1_k127_2890270_19 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000322 137.0
HFD1_k127_2890270_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 6.085e-267 827.0
HFD1_k127_2890270_20 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000003288 144.0
HFD1_k127_2890270_21 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000009906 93.0
HFD1_k127_2890270_22 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001184 86.0
HFD1_k127_2890270_23 - - - - 0.00000000000006507 74.0
HFD1_k127_2890270_24 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000004682 61.0
HFD1_k127_2890270_25 Transcriptional regulator - - - 0.000000005175 60.0
HFD1_k127_2890270_28 HNH endonuclease K07451 - - 0.0008741 42.0
HFD1_k127_2890270_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.158e-258 804.0
HFD1_k127_2890270_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 1.11e-225 706.0
HFD1_k127_2890270_5 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 554.0
HFD1_k127_2890270_6 Response regulator receiver K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 512.0
HFD1_k127_2890270_7 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 433.0
HFD1_k127_2890270_8 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 442.0
HFD1_k127_2890270_9 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 428.0
HFD1_k127_290867_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 998.0
HFD1_k127_290867_1 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 7.049e-305 940.0
HFD1_k127_290867_10 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 439.0
HFD1_k127_290867_11 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 439.0
HFD1_k127_290867_12 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 401.0
HFD1_k127_290867_13 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 400.0
HFD1_k127_290867_14 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 381.0
HFD1_k127_290867_15 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 379.0
HFD1_k127_290867_16 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
HFD1_k127_290867_17 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 346.0
HFD1_k127_290867_18 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 309.0
HFD1_k127_290867_19 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 309.0
HFD1_k127_290867_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 6.925e-254 786.0
HFD1_k127_290867_20 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002125 271.0
HFD1_k127_290867_21 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000004891 229.0
HFD1_k127_290867_22 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000003144 229.0
HFD1_k127_290867_23 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000003722 171.0
HFD1_k127_290867_24 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000000000001089 136.0
HFD1_k127_290867_25 Competence protein K02238 - - 0.0000000000000000000000000000000004188 143.0
HFD1_k127_290867_26 Competence protein K02238 - - 0.0000000000000000000000000002094 121.0
HFD1_k127_290867_27 Glyoxalase-like domain - - - 0.0000000000000001657 84.0
HFD1_k127_290867_28 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000007993 60.0
HFD1_k127_290867_29 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000009356 60.0
HFD1_k127_290867_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.769e-247 772.0
HFD1_k127_290867_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.614e-228 716.0
HFD1_k127_290867_5 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 9.808e-202 650.0
HFD1_k127_290867_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 513.0
HFD1_k127_290867_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 503.0
HFD1_k127_290867_8 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 509.0
HFD1_k127_290867_9 MoeA C-terminal region (domain IV) K03750 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 495.0
HFD1_k127_2963001_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1516.0
HFD1_k127_2963001_1 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.0 1329.0
HFD1_k127_2963001_10 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 573.0
HFD1_k127_2963001_11 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 523.0
HFD1_k127_2963001_12 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 520.0
HFD1_k127_2963001_13 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 501.0
HFD1_k127_2963001_14 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 474.0
HFD1_k127_2963001_15 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 417.0
HFD1_k127_2963001_16 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 416.0
HFD1_k127_2963001_17 KR domain K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 411.0
HFD1_k127_2963001_18 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 392.0
HFD1_k127_2963001_19 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 396.0
HFD1_k127_2963001_2 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 0.0 1161.0
HFD1_k127_2963001_20 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 371.0
HFD1_k127_2963001_21 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 371.0
HFD1_k127_2963001_22 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
HFD1_k127_2963001_23 Belongs to the FPP GGPP synthase family K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 358.0
HFD1_k127_2963001_24 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 355.0
HFD1_k127_2963001_25 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 349.0
HFD1_k127_2963001_26 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 340.0
HFD1_k127_2963001_27 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 328.0
HFD1_k127_2963001_28 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 311.0
HFD1_k127_2963001_29 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 302.0
HFD1_k127_2963001_3 Cobalamin biosynthesis protein CobT VWA domain K09883 - 6.6.1.2 6.717e-302 936.0
HFD1_k127_2963001_30 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 299.0
HFD1_k127_2963001_31 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001249 287.0
HFD1_k127_2963001_32 PFAM heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005816 273.0
HFD1_k127_2963001_33 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 273.0
HFD1_k127_2963001_34 Polyhydroxyalkanoate synthesis repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004386 268.0
HFD1_k127_2963001_35 NUDIX domain K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000009162 220.0
HFD1_k127_2963001_36 Class II Aldolase and Adducin N-terminal domain K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.00000000000000000000000000000000000000000000000000000000000003489 223.0
HFD1_k127_2963001_37 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000001326 217.0
HFD1_k127_2963001_38 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000000000000000000000000000000002483 218.0
HFD1_k127_2963001_39 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000006742 208.0
HFD1_k127_2963001_4 Belongs to the thiolase family K00626 - 2.3.1.9 3.127e-217 677.0
HFD1_k127_2963001_40 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000000000000000000000000001798 201.0
HFD1_k127_2963001_41 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000000424 200.0
HFD1_k127_2963001_42 Domain of unknown function (DUF4167) - - - 0.0000000000000000000000000000000000000000000000007574 184.0
HFD1_k127_2963001_43 - - - - 0.0000000000000000000000000000000000000001795 154.0
HFD1_k127_2963001_44 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.00000000000000000000000000000000000000046 149.0
HFD1_k127_2963001_45 structural constituent of ribosome K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000002068 142.0
HFD1_k127_2963001_46 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000705 145.0
HFD1_k127_2963001_47 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000003917 126.0
HFD1_k127_2963001_48 Excinuclease ABC, C subunit K07461 - - 0.00000000000000000000000000001246 121.0
HFD1_k127_2963001_49 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000007144 116.0
HFD1_k127_2963001_5 Sodium/hydrogen exchanger family K03316 - - 1.067e-216 687.0
HFD1_k127_2963001_50 GGDEF domain - - - 0.0000000000000000000009341 99.0
HFD1_k127_2963001_51 Tetratricopeptide repeat - - - 0.0000000000000366 77.0
HFD1_k127_2963001_52 - - - - 0.000000000003701 69.0
HFD1_k127_2963001_54 Antibiotic biosynthesis monooxygenase - - - 0.0000000006789 68.0
HFD1_k127_2963001_6 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 3.083e-209 656.0
HFD1_k127_2963001_7 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 2.891e-200 626.0
HFD1_k127_2963001_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 3.41e-198 626.0
HFD1_k127_2963001_9 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 582.0
HFD1_k127_3017749_0 Biotin carboxylase C-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 8.132e-256 793.0
HFD1_k127_3017749_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 590.0
HFD1_k127_3017749_2 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 581.0
HFD1_k127_3017749_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 380.0
HFD1_k127_3017749_4 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 369.0
HFD1_k127_3017749_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000287 206.0
HFD1_k127_3017749_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.00000000000000000000000000000000000000000000000002434 183.0
HFD1_k127_3017749_7 Dehydrogenase - - - 0.0000000003534 64.0
HFD1_k127_3017749_8 cheY-homologous receiver domain - - - 0.0003676 45.0
HFD1_k127_3129370_0 His Kinase A (phosphoacceptor) domain K13587 - 2.7.13.3 0.0 1133.0
HFD1_k127_3129370_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 492.0
HFD1_k127_3129370_2 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 450.0
HFD1_k127_3129370_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000001015 229.0
HFD1_k127_3129370_4 Flagellar biosynthesis protein, FliO - - - 0.000000000000000000000000000000000000000000001971 177.0
HFD1_k127_3129370_5 Protein of unknown function (DUF968) - - - 0.000000000000000000000000000002953 125.0
HFD1_k127_3129370_6 Protein of unknown function (DUF3309) - - - 0.0000000000000000003721 87.0
HFD1_k127_3129370_7 His Kinase A (phosphoacceptor) domain - - - 0.000000001529 66.0
HFD1_k127_3129370_8 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000004353 59.0
HFD1_k127_3129370_9 Class II flagellar assembly regulator - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0005817 44.0
HFD1_k127_3219983_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 595.0
HFD1_k127_3219983_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 333.0
HFD1_k127_3223419_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002055 261.0
HFD1_k127_3223419_1 Protein conserved in bacteria K09984 - - 0.00000000000000000000000000000000000000000000000000001667 189.0
HFD1_k127_3223419_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000008112 68.0
HFD1_k127_3223419_3 Flavin reductase like domain - - - 0.0002042 49.0
HFD1_k127_3274857_0 Periplasmic binding protein domain K01999 - - 2.362e-229 715.0
HFD1_k127_3274857_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 566.0
HFD1_k127_3274857_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 394.0
HFD1_k127_3274857_3 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 395.0
HFD1_k127_3274857_4 Protein of unknown function (DUF993) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 391.0
HFD1_k127_3274857_5 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 298.0
HFD1_k127_3274857_6 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002571 248.0
HFD1_k127_3274857_7 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000004919 221.0
HFD1_k127_3274857_8 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000004885 199.0
HFD1_k127_3376399_0 Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA K09461 - 1.14.13.40 0.0 1200.0
HFD1_k127_3376399_1 benzoate-CoA ligase K08295 - 6.2.1.32 9.944e-295 913.0
HFD1_k127_3376399_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000006612 153.0
HFD1_k127_3376399_11 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000001573 74.0
HFD1_k127_3376399_12 Sodium/calcium exchanger protein K07300 - - 0.0002294 44.0
HFD1_k127_3376399_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 5.624e-270 834.0
HFD1_k127_3376399_3 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 578.0
HFD1_k127_3376399_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 557.0
HFD1_k127_3376399_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 546.0
HFD1_k127_3376399_6 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 435.0
HFD1_k127_3376399_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009692 256.0
HFD1_k127_3376399_8 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000005886 176.0
HFD1_k127_3376399_9 Transglycosylase associated protein - - - 0.0000000000000000000000000000000000000548 144.0
HFD1_k127_3408181_0 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000006968 78.0
HFD1_k127_3408181_1 - - - - 0.00000000000005549 77.0
HFD1_k127_3408181_2 - - - - 0.000000000003827 70.0
HFD1_k127_3408181_3 Cytochrome P450 - - - 0.00000006349 57.0
HFD1_k127_3434905_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1346.0
HFD1_k127_3434905_1 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 532.0
HFD1_k127_3434905_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000507 186.0
HFD1_k127_3434905_3 - - - - 0.00000000000000000000000000000000002737 143.0
HFD1_k127_343763_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 3.353e-229 713.0
HFD1_k127_343763_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 9.094e-229 715.0
HFD1_k127_343763_10 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 374.0
HFD1_k127_343763_11 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 353.0
HFD1_k127_343763_12 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 341.0
HFD1_k127_343763_13 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 317.0
HFD1_k127_343763_14 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 316.0
HFD1_k127_343763_15 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009254 273.0
HFD1_k127_343763_16 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000106 239.0
HFD1_k127_343763_17 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000001911 206.0
HFD1_k127_343763_18 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.0000000000000000000000000000000000000000000000000002063 194.0
HFD1_k127_343763_2 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 3.935e-215 677.0
HFD1_k127_343763_20 - - - - 0.0000000000000000000000000000000000000004214 154.0
HFD1_k127_343763_21 SnoaL-like domain - - - 0.0000000000000000000261 96.0
HFD1_k127_343763_22 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000007345 72.0
HFD1_k127_343763_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 481.0
HFD1_k127_343763_4 Glycosyl transferase, family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 463.0
HFD1_k127_343763_5 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 466.0
HFD1_k127_343763_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 471.0
HFD1_k127_343763_7 Putative diguanylate phosphodiesterase K13593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 431.0
HFD1_k127_343763_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 396.0
HFD1_k127_343763_9 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 370.0
HFD1_k127_3441358_0 thiamine pyrophosphate protein TPP binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 488.0
HFD1_k127_3441358_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 421.0
HFD1_k127_3441358_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 381.0
HFD1_k127_3441358_3 COG0410 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 336.0
HFD1_k127_3441358_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 316.0
HFD1_k127_3441358_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001338 271.0
HFD1_k127_3462406_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1463.0
HFD1_k127_3462406_1 Domain of unknown function (DUF4175) - - - 8.496e-303 950.0
HFD1_k127_3462406_10 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 361.0
HFD1_k127_3462406_11 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 351.0
HFD1_k127_3462406_12 methionine biosynthesis protein (MetW) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 343.0
HFD1_k127_3462406_13 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 335.0
HFD1_k127_3462406_14 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 292.0
HFD1_k127_3462406_15 Thioredoxin-like - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 289.0
HFD1_k127_3462406_16 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003652 255.0
HFD1_k127_3462406_17 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000004145 211.0
HFD1_k127_3462406_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000035 195.0
HFD1_k127_3462406_19 CHAP domain - - - 0.00000000000000000000000000000000000000000001472 171.0
HFD1_k127_3462406_2 Peptidase family M23 - - - 1.275e-268 843.0
HFD1_k127_3462406_20 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000005839 142.0
HFD1_k127_3462406_21 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000002031 91.0
HFD1_k127_3462406_22 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000005018 78.0
HFD1_k127_3462406_23 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000001387 68.0
HFD1_k127_3462406_25 small periplasmic lipoprotein - - - 0.0000002078 56.0
HFD1_k127_3462406_26 - - - - 0.0000007176 53.0
HFD1_k127_3462406_3 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 5.231e-232 724.0
HFD1_k127_3462406_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 3.369e-209 657.0
HFD1_k127_3462406_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 1.198e-204 643.0
HFD1_k127_3462406_6 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 544.0
HFD1_k127_3462406_7 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 487.0
HFD1_k127_3462406_8 ATPases associated with a variety of cellular activities K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 397.0
HFD1_k127_3462406_9 Chorismate mutase type II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 361.0
HFD1_k127_3491695_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01271 - 3.4.13.9 1.257e-219 687.0
HFD1_k127_3491695_1 PFAM amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 434.0
HFD1_k127_3491695_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 304.0
HFD1_k127_3521861_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 565.0
HFD1_k127_3521861_1 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 400.0
HFD1_k127_3521861_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 350.0
HFD1_k127_3521861_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 324.0
HFD1_k127_3646046_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1143.0
HFD1_k127_3646046_1 Involved in the TonB-independent uptake of proteins K03641 - - 1.33e-230 719.0
HFD1_k127_3646046_10 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000003625 238.0
HFD1_k127_3646046_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000002949 218.0
HFD1_k127_3646046_12 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000006389 218.0
HFD1_k127_3646046_13 Cell division and transport-associated protein TolA - - - 0.00000000000000000000000000000000000000000000000000000000000002826 233.0
HFD1_k127_3646046_14 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000000000001535 213.0
HFD1_k127_3646046_15 Protein of unknown function (DUF2852) - - - 0.0000000000000000000000000000000000000000000000007446 179.0
HFD1_k127_3646046_16 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000001047 144.0
HFD1_k127_3646046_17 NIPSNAP - - - 0.000000000000000000000001299 111.0
HFD1_k127_3646046_2 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 535.0
HFD1_k127_3646046_3 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 433.0
HFD1_k127_3646046_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 411.0
HFD1_k127_3646046_5 MotA/TolQ/ExbB proton channel family K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 398.0
HFD1_k127_3646046_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 339.0
HFD1_k127_3646046_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 311.0
HFD1_k127_3646046_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001664 284.0
HFD1_k127_3646046_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001023 258.0
HFD1_k127_3653073_0 radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 474.0
HFD1_k127_3653073_1 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 464.0
HFD1_k127_3653073_2 Protein of unknown function (DUF3750) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 338.0
HFD1_k127_3653073_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001693 276.0
HFD1_k127_3653073_4 Glycosyl transferase group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000207 267.0
HFD1_k127_3653073_5 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.00000000000000000000000000000000000000000000000001389 186.0
HFD1_k127_3653073_6 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000008665 185.0
HFD1_k127_3653842_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 7.56e-260 814.0
HFD1_k127_3653842_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 374.0
HFD1_k127_3653842_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000001917 149.0
HFD1_k127_3653842_3 transcriptional - - - 0.0000000000000000000000000000000008248 134.0
HFD1_k127_368748_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 361.0
HFD1_k127_368748_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000862 197.0
HFD1_k127_368748_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000002016 80.0
HFD1_k127_368748_3 Thiamine pyrophosphate enzyme, central domain - - - 0.00003538 47.0
HFD1_k127_3958684_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1427.0
HFD1_k127_3958684_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1037.0
HFD1_k127_3958684_10 Iron-sulfur cluster-binding domain - - - 2.503e-201 633.0
HFD1_k127_3958684_11 Glycosyltransferase family 87 - - - 2.82e-198 631.0
HFD1_k127_3958684_12 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 526.0
HFD1_k127_3958684_13 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 509.0
HFD1_k127_3958684_14 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 505.0
HFD1_k127_3958684_15 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 497.0
HFD1_k127_3958684_16 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 472.0
HFD1_k127_3958684_17 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 446.0
HFD1_k127_3958684_18 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 364.0
HFD1_k127_3958684_19 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 366.0
HFD1_k127_3958684_2 Belongs to the TPP enzyme family K01577,K01652 - 2.2.1.6,4.1.1.8 0.0 1004.0
HFD1_k127_3958684_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 345.0
HFD1_k127_3958684_21 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 313.0
HFD1_k127_3958684_22 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 288.0
HFD1_k127_3958684_23 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
HFD1_k127_3958684_24 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002708 260.0
HFD1_k127_3958684_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002892 238.0
HFD1_k127_3958684_26 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000000001963 201.0
HFD1_k127_3958684_27 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000001305 209.0
HFD1_k127_3958684_28 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000003966 199.0
HFD1_k127_3958684_29 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000005572 179.0
HFD1_k127_3958684_3 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 2.518e-285 889.0
HFD1_k127_3958684_30 YCII-related domain - - - 0.0000000000000000000006487 98.0
HFD1_k127_3958684_31 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000002383 88.0
HFD1_k127_3958684_32 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000103 69.0
HFD1_k127_3958684_33 Lipocalin-like domain - - - 0.00000000008652 64.0
HFD1_k127_3958684_34 Bacterial SH3 domain - - - 0.000000001014 66.0
HFD1_k127_3958684_35 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000001837 65.0
HFD1_k127_3958684_36 Predicted permease - - - 0.000005071 50.0
HFD1_k127_3958684_37 - - - - 0.0003277 47.0
HFD1_k127_3958684_4 Tripartite tricarboxylate transporter TctA family K07793 - - 6.918e-276 853.0
HFD1_k127_3958684_5 Class II Aldolase and Adducin N-terminal domain - - - 1.029e-267 840.0
HFD1_k127_3958684_6 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 5.499e-259 808.0
HFD1_k127_3958684_7 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit - - - 4.666e-258 808.0
HFD1_k127_3958684_8 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.642e-234 730.0
HFD1_k127_3958684_9 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 1.64e-229 718.0
HFD1_k127_4008660_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 3.229e-307 959.0
HFD1_k127_4008660_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 5.804e-282 887.0
HFD1_k127_4008660_10 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 574.0
HFD1_k127_4008660_11 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 551.0
HFD1_k127_4008660_12 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 542.0
HFD1_k127_4008660_13 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 516.0
HFD1_k127_4008660_14 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 440.0
HFD1_k127_4008660_15 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 398.0
HFD1_k127_4008660_16 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 385.0
HFD1_k127_4008660_17 Phosphoribosyl-ATP pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 381.0
HFD1_k127_4008660_18 Amino-transferase class IV K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 374.0
HFD1_k127_4008660_19 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 350.0
HFD1_k127_4008660_2 Sigma-54 interaction domain K07712 - - 6.555e-266 823.0
HFD1_k127_4008660_20 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007955 288.0
HFD1_k127_4008660_21 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000005774 239.0
HFD1_k127_4008660_22 Polyketide cyclase / dehydrase and lipid transport K18588 - - 0.0000000000000000000000000000000000000000000000000000000000000000001252 232.0
HFD1_k127_4008660_23 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000002443 188.0
HFD1_k127_4008660_24 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000003646 161.0
HFD1_k127_4008660_25 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000001046 132.0
HFD1_k127_4008660_26 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000322 131.0
HFD1_k127_4008660_27 Septum formation initiator - - - 0.0000000000000000000000000000061 121.0
HFD1_k127_4008660_28 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000003215 118.0
HFD1_k127_4008660_29 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000001445 101.0
HFD1_k127_4008660_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 2.8e-261 812.0
HFD1_k127_4008660_30 PFAM Transglycosylase-associated protein - - - 0.00000000000000008932 83.0
HFD1_k127_4008660_31 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000003303 64.0
HFD1_k127_4008660_32 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000004175 64.0
HFD1_k127_4008660_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.362e-259 806.0
HFD1_k127_4008660_5 Sigma-54 interaction domain K13599 - - 6.139e-249 774.0
HFD1_k127_4008660_6 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 8.415e-205 646.0
HFD1_k127_4008660_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 1.503e-203 642.0
HFD1_k127_4008660_8 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 595.0
HFD1_k127_4008660_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 581.0
HFD1_k127_4064901_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2308.0
HFD1_k127_4064901_1 Major Facilitator Superfamily K02575 - - 0.0 1568.0
HFD1_k127_4064901_10 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 5.442e-203 639.0
HFD1_k127_4064901_11 Acts as a magnesium transporter K06213 - - 1.438e-195 621.0
HFD1_k127_4064901_12 Beta-agarase K01219 - 3.2.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 556.0
HFD1_k127_4064901_13 Transglycosylase SLT domain K00786,K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 541.0
HFD1_k127_4064901_14 Cytochrome c K17230 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 521.0
HFD1_k127_4064901_15 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 507.0
HFD1_k127_4064901_16 tRNA synthetases class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 484.0
HFD1_k127_4064901_17 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 472.0
HFD1_k127_4064901_18 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 461.0
HFD1_k127_4064901_19 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 382.0
HFD1_k127_4064901_2 Belongs to the 5'-nucleotidase family K17224 - - 6.597e-285 884.0
HFD1_k127_4064901_20 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 375.0
HFD1_k127_4064901_21 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 360.0
HFD1_k127_4064901_22 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 358.0
HFD1_k127_4064901_23 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 344.0
HFD1_k127_4064901_24 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 321.0
HFD1_k127_4064901_25 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 322.0
HFD1_k127_4064901_26 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 310.0
HFD1_k127_4064901_27 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 304.0
HFD1_k127_4064901_28 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 303.0
HFD1_k127_4064901_29 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 295.0
HFD1_k127_4064901_3 Involved in beta-(1-- 2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 3.371e-249 783.0
HFD1_k127_4064901_30 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 286.0
HFD1_k127_4064901_31 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005257 277.0
HFD1_k127_4064901_32 Cytochrome C K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002247 265.0
HFD1_k127_4064901_33 Putative vitamin uptake transporter K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 260.0
HFD1_k127_4064901_34 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003884 263.0
HFD1_k127_4064901_35 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003313 255.0
HFD1_k127_4064901_36 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004427 237.0
HFD1_k127_4064901_37 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.00000000000000000000000000000000000000000000000000000000002104 213.0
HFD1_k127_4064901_38 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000000000000006238 179.0
HFD1_k127_4064901_39 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000002805 178.0
HFD1_k127_4064901_4 Thiamine pyrophosphate enzyme, central domain - - - 4.924e-239 753.0
HFD1_k127_4064901_40 transcriptional regulator, ArsR family - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000001976 144.0
HFD1_k127_4064901_41 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000009496 134.0
HFD1_k127_4064901_42 Regulatory protein SoxS - - - 0.000000000000000000000000000000001333 135.0
HFD1_k127_4064901_43 Diguanylate cyclase - - - 0.000000000000000000000000000000002813 131.0
HFD1_k127_4064901_44 Cupredoxin-like domain - - - 0.0000000000000000000000000000944 119.0
HFD1_k127_4064901_45 - - - - 0.000000000000000000000000001773 121.0
HFD1_k127_4064901_46 transcriptional regulator, XRE family K07726 - - 0.0000000000000000000000003405 108.0
HFD1_k127_4064901_47 Respiratory nitrate reductase beta C-terminal K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.000000000000000000000008785 101.0
HFD1_k127_4064901_48 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000003137 101.0
HFD1_k127_4064901_49 Lysozyme inhibitor LprI - - - 0.0000000000000000000005594 108.0
HFD1_k127_4064901_5 Aldehyde dehydrogenase family K00130 - 1.2.1.8 2.28e-224 705.0
HFD1_k127_4064901_50 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000005525 94.0
HFD1_k127_4064901_51 Diguanylate cyclase - - - 0.00000000000000033 82.0
HFD1_k127_4064901_52 GGDEF domain - - - 0.0000002113 60.0
HFD1_k127_4064901_53 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000003847 53.0
HFD1_k127_4064901_54 Diguanylate cyclase - - - 0.00004465 50.0
HFD1_k127_4064901_6 Acyl-CoA dehydrogenase, middle domain K00253 - 1.3.8.4 3.988e-218 681.0
HFD1_k127_4064901_7 Mo-co oxidoreductase dimerisation domain K17225 - - 8.368e-216 677.0
HFD1_k127_4064901_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05350 - 3.2.1.21 7.065e-215 676.0
HFD1_k127_4064901_9 ABC transporter transmembrane region 2 K02471 - - 3.656e-210 670.0
HFD1_k127_4071337_0 CHASE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 489.0
HFD1_k127_4071337_1 Proteasome-type protease K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 410.0
HFD1_k127_4071337_10 - - - - 0.00014 47.0
HFD1_k127_4071337_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 358.0
HFD1_k127_4071337_3 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 343.0
HFD1_k127_4071337_4 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006254 272.0
HFD1_k127_4071337_5 ChrR Cupin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000496 217.0
HFD1_k127_4071337_6 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000000000396 178.0
HFD1_k127_4071337_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000216 176.0
HFD1_k127_4071337_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000001692 99.0
HFD1_k127_4071337_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000007036 79.0
HFD1_k127_4076468_0 DNA polymerase K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1699.0
HFD1_k127_4076468_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 1.044e-238 743.0
HFD1_k127_4076468_10 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 349.0
HFD1_k127_4076468_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 322.0
HFD1_k127_4076468_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 286.0
HFD1_k127_4076468_13 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000007506 249.0
HFD1_k127_4076468_14 Copper resistance protein D K07245 - - 0.0000000000000000000000000000000000001519 151.0
HFD1_k127_4076468_15 CopC domain K07156 - - 0.000000000000000000000000007063 115.0
HFD1_k127_4076468_16 - - - - 0.00000000000000000009854 94.0
HFD1_k127_4076468_17 - - - - 0.0002274 44.0
HFD1_k127_4076468_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.664e-234 738.0
HFD1_k127_4076468_3 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 4.557e-227 710.0
HFD1_k127_4076468_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 561.0
HFD1_k127_4076468_5 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 535.0
HFD1_k127_4076468_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 529.0
HFD1_k127_4076468_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 468.0
HFD1_k127_4076468_8 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 435.0
HFD1_k127_4076468_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 369.0
HFD1_k127_4076978_0 ABC transporter K15738 - - 8.229e-316 975.0
HFD1_k127_4076978_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 8.073e-303 939.0
HFD1_k127_4076978_10 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 436.0
HFD1_k127_4076978_11 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 431.0
HFD1_k127_4076978_12 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 421.0
HFD1_k127_4076978_13 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 419.0
HFD1_k127_4076978_14 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 410.0
HFD1_k127_4076978_15 Amidohydrolase K10220 - 4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 411.0
HFD1_k127_4076978_16 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 390.0
HFD1_k127_4076978_17 metal-dependent hydrolase of the TIM-barrel fold K07045,K14333,K15063 - 4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 361.0
HFD1_k127_4076978_18 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 348.0
HFD1_k127_4076978_19 COG0410 ABC-type branched-chain amino acid transport systems ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 338.0
HFD1_k127_4076978_2 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 1.676e-277 866.0
HFD1_k127_4076978_20 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 325.0
HFD1_k127_4076978_21 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 314.0
HFD1_k127_4076978_22 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001115 281.0
HFD1_k127_4076978_23 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004331 262.0
HFD1_k127_4076978_24 UDP binding domain K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000001099 268.0
HFD1_k127_4076978_25 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002224 265.0
HFD1_k127_4076978_26 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000002237 255.0
HFD1_k127_4076978_27 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000001078 233.0
HFD1_k127_4076978_28 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000001265 208.0
HFD1_k127_4076978_29 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000003962 183.0
HFD1_k127_4076978_3 Polysaccharide biosynthesis protein K13013 - - 1.759e-276 865.0
HFD1_k127_4076978_30 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000009403 172.0
HFD1_k127_4076978_31 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000001299 117.0
HFD1_k127_4076978_32 Cupin domain - - - 0.000000000000000000000000002073 116.0
HFD1_k127_4076978_33 - - - - 0.0000000000000000000000001198 109.0
HFD1_k127_4076978_34 - - - - 0.00000000000000000000004076 102.0
HFD1_k127_4076978_36 - - - - 0.000000000003382 69.0
HFD1_k127_4076978_37 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000001576 51.0
HFD1_k127_4076978_4 Alcohol dehydrogenase GroES-like domain - - - 2.919e-203 638.0
HFD1_k127_4076978_5 Transglycosylase SLT domain - - - 3.816e-194 621.0
HFD1_k127_4076978_6 ABC transporter substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 590.0
HFD1_k127_4076978_7 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 512.0
HFD1_k127_4076978_8 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 509.0
HFD1_k127_4076978_9 Major facilitator superfamily K03449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 441.0
HFD1_k127_4133541_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.443e-194 616.0
HFD1_k127_4133541_1 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 339.0
HFD1_k127_4133541_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000002843 227.0
HFD1_k127_4133541_3 ATP-grasp domain K09181 - - 0.000000000000000000000000000000000000000000000002334 179.0
HFD1_k127_4133541_4 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000006772 74.0
HFD1_k127_4146331_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1025.0
HFD1_k127_4146331_1 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 611.0
HFD1_k127_4146331_10 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 362.0
HFD1_k127_4146331_11 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 329.0
HFD1_k127_4146331_12 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 306.0
HFD1_k127_4146331_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 299.0
HFD1_k127_4146331_14 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 314.0
HFD1_k127_4146331_15 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006584 283.0
HFD1_k127_4146331_16 SAF K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003704 273.0
HFD1_k127_4146331_17 pilus assembly protein ATPase CpaF K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005223 241.0
HFD1_k127_4146331_18 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000001703 235.0
HFD1_k127_4146331_19 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000009847 220.0
HFD1_k127_4146331_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 510.0
HFD1_k127_4146331_20 binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000002645 219.0
HFD1_k127_4146331_21 EVE domain - - - 0.0000000000000000000000000000000000000000000000000002343 188.0
HFD1_k127_4146331_22 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000007716 189.0
HFD1_k127_4146331_23 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000000000000000000000000000000001982 181.0
HFD1_k127_4146331_24 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000003195 179.0
HFD1_k127_4146331_25 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000008499 178.0
HFD1_k127_4146331_26 synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000001157 168.0
HFD1_k127_4146331_27 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000004849 160.0
HFD1_k127_4146331_28 Pilus formation protein N terminal region K02280 - - 0.00000000000000000000000000000000000000009651 158.0
HFD1_k127_4146331_29 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000008115 134.0
HFD1_k127_4146331_3 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 469.0
HFD1_k127_4146331_30 Protein of unknown function (DUF1761) - - - 0.00000000000000000000000000000004912 129.0
HFD1_k127_4146331_31 histidine kinase A domain protein - - - 0.000000000000000000000000000002608 139.0
HFD1_k127_4146331_32 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000004164 119.0
HFD1_k127_4146331_33 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000007248 120.0
HFD1_k127_4146331_34 protein tyrosine kinase activity - - - 0.0000000000001243 75.0
HFD1_k127_4146331_35 type II secretion system K12510 - - 0.0000000001047 69.0
HFD1_k127_4146331_36 Pilus formation protein N terminal region K02280 - - 0.00009971 50.0
HFD1_k127_4146331_4 Major facilitator Superfamily K05939 - 2.3.1.40,6.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 471.0
HFD1_k127_4146331_5 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 456.0
HFD1_k127_4146331_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 434.0
HFD1_k127_4146331_7 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 417.0
HFD1_k127_4146331_8 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 400.0
HFD1_k127_4146331_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 371.0
HFD1_k127_4192682_0 TIGRFAM cytochrome c oxidase, cbb3-type, subunit I K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 9.095e-318 977.0
HFD1_k127_4192682_1 4Fe-4S ferredoxin, iron-sulfur binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.239e-224 706.0
HFD1_k127_4192682_10 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000002361 258.0
HFD1_k127_4192682_11 response regulator K14987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001024 250.0
HFD1_k127_4192682_12 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856,K01860,K19802 - 5.1.1.20,5.5.1.1,5.5.1.7 0.0000000000000000000000000000000000000000000000000000000003898 217.0
HFD1_k127_4192682_13 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000000000001728 190.0
HFD1_k127_4192682_14 LTXXQ motif family protein - - - 0.00000000000000000000000000000000000000000008943 167.0
HFD1_k127_4192682_15 FixH - - - 0.0000000000000000000000000000000000000008819 153.0
HFD1_k127_4192682_16 Cbb3-type cytochrome oxidase K00407 - - 0.000000000000000648 78.0
HFD1_k127_4192682_2 Histidine kinase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 564.0
HFD1_k127_4192682_3 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 523.0
HFD1_k127_4192682_4 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 413.0
HFD1_k127_4192682_5 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 411.0
HFD1_k127_4192682_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 304.0
HFD1_k127_4192682_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 289.0
HFD1_k127_4192682_8 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
HFD1_k127_4192682_9 Crp Fnr family K01420,K15861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 267.0
HFD1_k127_4235825_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 8.291e-308 949.0
HFD1_k127_4235825_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 464.0
HFD1_k127_4235825_10 Ribbon-helix-helix domain - - - 0.000000000000000000001417 95.0
HFD1_k127_4235825_11 - - - - 0.00000000000000000003047 91.0
HFD1_k127_4235825_12 - - - - 0.00000000000008951 78.0
HFD1_k127_4235825_13 - - - - 0.000000000001086 70.0
HFD1_k127_4235825_14 PilZ domain - - - 0.00000001459 61.0
HFD1_k127_4235825_15 ABC transporter K01996 - - 0.0000001062 55.0
HFD1_k127_4235825_16 ABC transporter K01996 - - 0.0000003975 53.0
HFD1_k127_4235825_2 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 338.0
HFD1_k127_4235825_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 317.0
HFD1_k127_4235825_4 Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 315.0
HFD1_k127_4235825_5 Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000004778 195.0
HFD1_k127_4235825_6 Cupin domain - - - 0.000000000000000000000000000000000000000000006053 168.0
HFD1_k127_4235825_7 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000000009893 147.0
HFD1_k127_4235825_8 Cold shock K03704 - - 0.0000000000000000000000000002248 115.0
HFD1_k127_4235825_9 diguanylate cyclase - - - 0.000000000000000000000003123 108.0
HFD1_k127_4283019_0 PFAM isochorismatase hydrolase - - - 0.000000000000000000000001133 110.0
HFD1_k127_4283019_1 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000001205 103.0
HFD1_k127_4283019_2 Cysteine dioxygenase type I - - - 0.0000004954 61.0
HFD1_k127_4314556_0 Aerotolerance regulator N-terminal - - - 0.0 1230.0
HFD1_k127_4314556_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 3.583e-221 690.0
HFD1_k127_4314556_10 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 302.0
HFD1_k127_4314556_11 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
HFD1_k127_4314556_12 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006648 277.0
HFD1_k127_4314556_13 Protein of unknown function (DUF1285) K09986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 274.0
HFD1_k127_4314556_14 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000001981 207.0
HFD1_k127_4314556_15 Electron transfer DM13 - - - 0.0000000000000000000000000000000000000001607 154.0
HFD1_k127_4314556_16 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000004508 130.0
HFD1_k127_4314556_17 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000001055 113.0
HFD1_k127_4314556_18 - - - - 0.0000000000000000000000008588 111.0
HFD1_k127_4314556_19 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000008375 62.0
HFD1_k127_4314556_2 ATPase family associated with various cellular activities (AAA) K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 550.0
HFD1_k127_4314556_20 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000001054 54.0
HFD1_k127_4314556_21 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0001659 47.0
HFD1_k127_4314556_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 518.0
HFD1_k127_4314556_4 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 497.0
HFD1_k127_4314556_5 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 474.0
HFD1_k127_4314556_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 455.0
HFD1_k127_4314556_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 382.0
HFD1_k127_4314556_8 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 331.0
HFD1_k127_4314556_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 320.0
HFD1_k127_4353100_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 541.0
HFD1_k127_4353100_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000105 275.0
HFD1_k127_4353100_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000328 206.0
HFD1_k127_4353100_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000008081 134.0
HFD1_k127_4353100_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000001408 133.0
HFD1_k127_4429018_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 541.0
HFD1_k127_4429018_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 474.0
HFD1_k127_4429018_10 COG3547 Transposase and inactivated derivatives - - - 0.00005332 45.0
HFD1_k127_4429018_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 341.0
HFD1_k127_4429018_3 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 323.0
HFD1_k127_4429018_4 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 299.0
HFD1_k127_4429018_5 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 297.0
HFD1_k127_4429018_6 CDP-archaeol synthase K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000001096 196.0
HFD1_k127_4429018_7 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.000000000000000000000002026 106.0
HFD1_k127_4429018_8 SPW repeat - - - 0.00000000000000000000008778 98.0
HFD1_k127_4429018_9 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.00000000000232 67.0
HFD1_k127_4437987_0 Acyl transferase domain - - - 0.0 1119.0
HFD1_k127_4437987_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000003272 203.0
HFD1_k127_4454471_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1627.0
HFD1_k127_4454471_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1142.0
HFD1_k127_4454471_10 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005407 284.0
HFD1_k127_4454471_11 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005983 267.0
HFD1_k127_4454471_12 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006731 258.0
HFD1_k127_4454471_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001675 261.0
HFD1_k127_4454471_14 - - - - 0.00000000000000000000000000000000000000000000000000000001332 207.0
HFD1_k127_4454471_15 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000000000000000000000001704 189.0
HFD1_k127_4454471_16 YtkA-like - - - 0.000000000000000000000000000000000000000000000000005991 183.0
HFD1_k127_4454471_17 - - - - 0.00000000000000000000000000000000000000000000005285 174.0
HFD1_k127_4454471_18 - - - - 0.00000000000000000000000000000000000000000001887 162.0
HFD1_k127_4454471_19 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000008492 157.0
HFD1_k127_4454471_2 Multicopper oxidase K22348 - 1.16.3.3 1.45e-249 778.0
HFD1_k127_4454471_20 Zinc-finger domain - - - 0.0000000000000000000000000000000000004303 140.0
HFD1_k127_4454471_21 Copper binding periplasmic protein CusF - - - 0.0000000000000000000000000002046 118.0
HFD1_k127_4454471_22 Protein of unknown function (DUF3126) - - - 0.00000000000000000000001056 106.0
HFD1_k127_4454471_23 - - - - 0.00000000000000000001454 95.0
HFD1_k127_4454471_24 - - - - 0.00000000000000001038 91.0
HFD1_k127_4454471_25 Protein of unknown function (DUF2933) - - - 0.00000000000000001801 83.0
HFD1_k127_4454471_26 - - - - 0.0000000000000001098 81.0
HFD1_k127_4454471_27 Protein of unknown function (DUF2892) - - - 0.0000000000000002177 80.0
HFD1_k127_4454471_28 - - - - 0.000000000000002053 82.0
HFD1_k127_4454471_29 - - - - 0.0000000000322 70.0
HFD1_k127_4454471_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 547.0
HFD1_k127_4454471_30 ChrR Cupin-like domain - - - 0.00000003239 54.0
HFD1_k127_4454471_31 - - - - 0.00004346 49.0
HFD1_k127_4454471_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 519.0
HFD1_k127_4454471_5 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 503.0
HFD1_k127_4454471_6 Serine acetyltransferase, N-terminal K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 444.0
HFD1_k127_4454471_7 FAD binding domain K00480 - 1.14.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 416.0
HFD1_k127_4454471_8 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 355.0
HFD1_k127_4454471_9 LamB/YcsF family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 298.0
HFD1_k127_4800546_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.254e-202 644.0
HFD1_k127_4800546_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 484.0
HFD1_k127_4800546_2 transport protein CorA K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 482.0
HFD1_k127_4800546_3 3-beta hydroxysteroid dehydrogenase/isomerase family K18981 - 1.1.1.203 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 400.0
HFD1_k127_4800546_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000033 209.0
HFD1_k127_4800546_5 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000006899 182.0
HFD1_k127_4800546_6 PFAM Integrase catalytic K07497 - - 0.0000001065 54.0
HFD1_k127_4824425_0 Thiamine pyrophosphate enzyme, central domain K03852 - 2.3.3.15 0.0 1114.0
HFD1_k127_4824425_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4 6.254e-283 888.0
HFD1_k127_4824425_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000001236 237.0
HFD1_k127_4824425_11 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000001606 216.0
HFD1_k127_4824425_12 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000004958 197.0
HFD1_k127_4824425_13 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000000007885 188.0
HFD1_k127_4824425_14 FixH - - - 0.000000000000000005289 86.0
HFD1_k127_4824425_15 Cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000001544 79.0
HFD1_k127_4824425_16 heme oxygenase (decyclizing) activity K21481 - 1.14.99.57 0.00000000000009225 79.0
HFD1_k127_4824425_17 Cytochrome P460 - - - 0.00000001108 57.0
HFD1_k127_4824425_18 Protein of unknown function (DUF3551) - - - 0.0007529 46.0
HFD1_k127_4824425_2 Tripartite tricarboxylate transporter TctA family K07793 - - 8.099e-255 794.0
HFD1_k127_4824425_3 Aldehyde dehydrogenase family K13922,K15515 - 1.2.1.81,1.2.1.87 2.582e-205 650.0
HFD1_k127_4824425_4 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 1.005e-200 629.0
HFD1_k127_4824425_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 517.0
HFD1_k127_4824425_6 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 507.0
HFD1_k127_4824425_7 phosphate acetyltransferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 439.0
HFD1_k127_4824425_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 398.0
HFD1_k127_4824425_9 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 402.0
HFD1_k127_4832493_0 PFAM NAD-glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.0 1827.0
HFD1_k127_4832493_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1423.0
HFD1_k127_4832493_10 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.718e-212 674.0
HFD1_k127_4832493_11 Ammonium Transporter K03320 - - 5.898e-194 613.0
HFD1_k127_4832493_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 603.0
HFD1_k127_4832493_13 Aminotransferase class I and II K14261,K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 570.0
HFD1_k127_4832493_14 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 565.0
HFD1_k127_4832493_15 Pantothenic acid kinase K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 524.0
HFD1_k127_4832493_16 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 503.0
HFD1_k127_4832493_17 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 481.0
HFD1_k127_4832493_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 460.0
HFD1_k127_4832493_19 Tetratricopeptide repeat K03671,K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 453.0
HFD1_k127_4832493_2 Ftsk_gamma K03466 - - 0.0 1042.0
HFD1_k127_4832493_20 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 440.0
HFD1_k127_4832493_21 acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 435.0
HFD1_k127_4832493_22 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 415.0
HFD1_k127_4832493_23 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 411.0
HFD1_k127_4832493_24 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 406.0
HFD1_k127_4832493_25 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 402.0
HFD1_k127_4832493_26 Acetyltransferase (GNAT) domain K22310 - 2.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 404.0
HFD1_k127_4832493_27 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 393.0
HFD1_k127_4832493_28 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 370.0
HFD1_k127_4832493_29 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 363.0
HFD1_k127_4832493_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.53e-306 949.0
HFD1_k127_4832493_30 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 359.0
HFD1_k127_4832493_31 Imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 340.0
HFD1_k127_4832493_32 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 335.0
HFD1_k127_4832493_33 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 327.0
HFD1_k127_4832493_34 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 317.0
HFD1_k127_4832493_35 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 311.0
HFD1_k127_4832493_36 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 320.0
HFD1_k127_4832493_37 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 297.0
HFD1_k127_4832493_38 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 293.0
HFD1_k127_4832493_39 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 288.0
HFD1_k127_4832493_4 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 5.282e-290 904.0
HFD1_k127_4832493_40 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
HFD1_k127_4832493_41 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003348 268.0
HFD1_k127_4832493_42 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000006898 255.0
HFD1_k127_4832493_43 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003033 242.0
HFD1_k127_4832493_44 YbaK prolyl-tRNA synthetase K19055 - - 0.00000000000000000000000000000000000000000000000000000000000000000001599 236.0
HFD1_k127_4832493_45 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000003343 240.0
HFD1_k127_4832493_46 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000006059 216.0
HFD1_k127_4832493_47 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000001171 210.0
HFD1_k127_4832493_48 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000001459 211.0
HFD1_k127_4832493_49 Lipopolysaccharide-assembly K03643 - - 0.0000000000000000000000000000000000000000000000000000000009216 207.0
HFD1_k127_4832493_5 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.847e-266 827.0
HFD1_k127_4832493_50 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000003687 200.0
HFD1_k127_4832493_51 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000005311 193.0
HFD1_k127_4832493_52 Smr domain - - - 0.00000000000000000000000000000000000000000000000000004308 195.0
HFD1_k127_4832493_53 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000002625 183.0
HFD1_k127_4832493_54 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000001615 181.0
HFD1_k127_4832493_55 Protein of unknown function (DUF2927) - - - 0.00000000000000000000000000000000000000009803 160.0
HFD1_k127_4832493_56 Protein of unknown function (DUF2628) - - - 0.0000000000000000000000000000000000000008662 153.0
HFD1_k127_4832493_57 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000001954 138.0
HFD1_k127_4832493_58 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.000000000000000000000000000007299 121.0
HFD1_k127_4832493_59 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000000002267 111.0
HFD1_k127_4832493_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.618e-254 786.0
HFD1_k127_4832493_60 - - - - 0.000000000000000000000000004534 117.0
HFD1_k127_4832493_61 Magnesium chelatase, subunit ChlI K07391 - - 0.000000000000000000000000196 110.0
HFD1_k127_4832493_62 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.000000000000000003638 89.0
HFD1_k127_4832493_63 - - - - 0.000000000000003212 76.0
HFD1_k127_4832493_64 Histidine kinase-like ATPases - - - 0.00000000000001259 78.0
HFD1_k127_4832493_65 Response regulator receiver protein - - - 0.00000000001553 70.0
HFD1_k127_4832493_66 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.0000000002312 72.0
HFD1_k127_4832493_67 - - - - 0.0000001354 54.0
HFD1_k127_4832493_68 Staphylococcal nuclease homologue - - - 0.0000003717 61.0
HFD1_k127_4832493_7 Ammonium Transporter K03320 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015291,GO:0015292,GO:0015669,GO:0015670,GO:0015696,GO:0015893,GO:0016020,GO:0016021,GO:0019755,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098655 - 3.55e-239 747.0
HFD1_k127_4832493_8 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.061e-235 734.0
HFD1_k127_4832493_9 Heparinase II/III-like protein - - - 8.458e-215 683.0
HFD1_k127_4842061_0 Histidine kinase K02480 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000005993 246.0
HFD1_k127_4842061_1 Efflux ABC transporter permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000007114 226.0
HFD1_k127_4842061_2 PFAM regulatory protein LuxR - - - 0.0000000000000000002902 88.0
HFD1_k127_4879626_0 FAD binding domain K14974 - 1.14.13.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 608.0
HFD1_k127_4879626_1 salicylate hydroxylase K00480,K22270 - 1.14.13.1,1.14.13.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 485.0
HFD1_k127_4879626_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 346.0
HFD1_k127_4879626_3 Ceramidase - - - 0.00000000000000000000000000000000000000000000000000000000008953 211.0
HFD1_k127_4879626_4 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000000000000000000975 147.0
HFD1_k127_4879626_5 Amidohydrolase K10221 - 3.1.1.57 0.0000000000000000000000007016 105.0
HFD1_k127_4879626_6 Ribbon-helix-helix domain - - - 0.00000000000000000000003942 101.0
HFD1_k127_4940552_0 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 361.0
HFD1_k127_4940552_1 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 298.0
HFD1_k127_4940552_2 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000005715 191.0
HFD1_k127_4940552_3 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000001626 161.0
HFD1_k127_4977915_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000004658 126.0
HFD1_k127_4977915_1 COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000001289 67.0
HFD1_k127_5000267_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1390.0
HFD1_k127_5000267_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1241.0
HFD1_k127_5000267_10 SpoU rRNA Methylase family K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 559.0
HFD1_k127_5000267_11 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 542.0
HFD1_k127_5000267_12 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 507.0
HFD1_k127_5000267_13 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 512.0
HFD1_k127_5000267_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 511.0
HFD1_k127_5000267_15 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 517.0
HFD1_k127_5000267_16 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 491.0
HFD1_k127_5000267_17 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 492.0
HFD1_k127_5000267_18 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 479.0
HFD1_k127_5000267_19 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 462.0
HFD1_k127_5000267_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1233.0
HFD1_k127_5000267_20 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 449.0
HFD1_k127_5000267_21 Branched-chain amino acid ATP-binding cassette transporter K01995,K15783 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 3.5.4.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 437.0
HFD1_k127_5000267_22 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 415.0
HFD1_k127_5000267_23 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 404.0
HFD1_k127_5000267_24 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 396.0
HFD1_k127_5000267_25 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 382.0
HFD1_k127_5000267_26 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 357.0
HFD1_k127_5000267_27 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 347.0
HFD1_k127_5000267_28 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 340.0
HFD1_k127_5000267_29 helix_turn_helix, arabinose operon control protein K18954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 341.0
HFD1_k127_5000267_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 4.081e-235 732.0
HFD1_k127_5000267_30 Major Facilitator Superfamily K08167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 344.0
HFD1_k127_5000267_31 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 331.0
HFD1_k127_5000267_32 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 322.0
HFD1_k127_5000267_33 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 318.0
HFD1_k127_5000267_34 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 313.0
HFD1_k127_5000267_35 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 317.0
HFD1_k127_5000267_36 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 308.0
HFD1_k127_5000267_37 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 292.0
HFD1_k127_5000267_38 membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 287.0
HFD1_k127_5000267_39 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005078 273.0
HFD1_k127_5000267_4 Probable molybdopterin binding domain K07141 - 2.7.7.76 3.452e-233 732.0
HFD1_k127_5000267_40 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
HFD1_k127_5000267_41 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003964 243.0
HFD1_k127_5000267_42 Bile acid K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002708 249.0
HFD1_k127_5000267_43 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000002429 216.0
HFD1_k127_5000267_44 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000000000000006533 205.0
HFD1_k127_5000267_45 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000000000000000000000184 198.0
HFD1_k127_5000267_46 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000003973 205.0
HFD1_k127_5000267_47 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000006137 201.0
HFD1_k127_5000267_48 Cellulose biosynthesis protein BcsS - - - 0.00000000000000000000000000000000000000000000000000347 191.0
HFD1_k127_5000267_49 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000004299 173.0
HFD1_k127_5000267_5 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.244e-229 714.0
HFD1_k127_5000267_50 Domain of unknown function (DUF1476) - - - 0.00000000000000000000000000000000000002369 147.0
HFD1_k127_5000267_51 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000004911 137.0
HFD1_k127_5000267_52 - - - - 0.000000000000000000000000000000000005742 141.0
HFD1_k127_5000267_53 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000000003189 133.0
HFD1_k127_5000267_54 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000007768 112.0
HFD1_k127_5000267_55 KTSC domain - - - 0.000000000000001142 78.0
HFD1_k127_5000267_56 symbiont process K00612 - - 0.0000000000000542 81.0
HFD1_k127_5000267_57 oxidation-reduction process K09022 - 3.5.99.10 0.00000001257 60.0
HFD1_k127_5000267_58 PFAM AMP-dependent synthetase and ligase K18687 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 6.2.1.41 0.00000008338 58.0
HFD1_k127_5000267_59 - - - - 0.00002358 49.0
HFD1_k127_5000267_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.014e-213 666.0
HFD1_k127_5000267_60 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00612 - - 0.00004156 46.0
HFD1_k127_5000267_7 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 1.553e-198 623.0
HFD1_k127_5000267_8 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 614.0
HFD1_k127_5000267_9 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 557.0
HFD1_k127_5011843_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1145.0
HFD1_k127_5011843_1 Glycosyl hydrolases family 15 - - - 1.984e-274 856.0
HFD1_k127_5011843_10 PFAM transglutaminase family protein cysteine peptidase, BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005048 281.0
HFD1_k127_5011843_11 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005801 275.0
HFD1_k127_5011843_12 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009312 268.0
HFD1_k127_5011843_13 NifU-like N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004074 239.0
HFD1_k127_5011843_14 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000001535 220.0
HFD1_k127_5011843_15 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000003928 228.0
HFD1_k127_5011843_16 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000000000000001345 160.0
HFD1_k127_5011843_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000002457 154.0
HFD1_k127_5011843_18 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000005496 121.0
HFD1_k127_5011843_19 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000005813 108.0
HFD1_k127_5011843_2 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 549.0
HFD1_k127_5011843_20 Ribbon-helix-helix domain - - - 0.0000000000000000000003163 100.0
HFD1_k127_5011843_21 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000004769 94.0
HFD1_k127_5011843_22 PAS domain - - - 0.000000007452 64.0
HFD1_k127_5011843_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 516.0
HFD1_k127_5011843_4 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 408.0
HFD1_k127_5011843_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 387.0
HFD1_k127_5011843_6 C-C_Bond_Lyase of the TIM-Barrel fold K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 377.0
HFD1_k127_5011843_7 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 321.0
HFD1_k127_5011843_8 periplasmic protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 316.0
HFD1_k127_5011843_9 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 289.0
HFD1_k127_5014824_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1369.0
HFD1_k127_5014824_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1169.0
HFD1_k127_5014824_10 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 550.0
HFD1_k127_5014824_11 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 524.0
HFD1_k127_5014824_12 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 495.0
HFD1_k127_5014824_13 RNA polymerase sigma factor RpoH K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 495.0
HFD1_k127_5014824_14 nitrate ABC transporter K02050,K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 479.0
HFD1_k127_5014824_15 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 451.0
HFD1_k127_5014824_16 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 389.0
HFD1_k127_5014824_17 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 383.0
HFD1_k127_5014824_18 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 372.0
HFD1_k127_5014824_19 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 339.0
HFD1_k127_5014824_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 7.471e-274 849.0
HFD1_k127_5014824_20 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004961 277.0
HFD1_k127_5014824_21 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001292 267.0
HFD1_k127_5014824_22 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000009109 276.0
HFD1_k127_5014824_23 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002289 237.0
HFD1_k127_5014824_24 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000002616 189.0
HFD1_k127_5014824_25 - - - - 0.0000000000000000000000000000000000000000000001432 176.0
HFD1_k127_5014824_26 Lipocalin-like domain - - - 0.00000000000000000000000009866 113.0
HFD1_k127_5014824_27 KR domain - - - 0.0000000000000000000002282 100.0
HFD1_k127_5014824_28 SOS response K14160 - - 0.000000000000000000002965 104.0
HFD1_k127_5014824_29 - - - - 0.000000000000001142 78.0
HFD1_k127_5014824_3 NMT1-like family K15576 - - 2.546e-251 782.0
HFD1_k127_5014824_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.571e-228 714.0
HFD1_k127_5014824_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 1.236e-223 701.0
HFD1_k127_5014824_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 2.412e-217 681.0
HFD1_k127_5014824_7 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 1.75e-211 662.0
HFD1_k127_5014824_8 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 599.0
HFD1_k127_5014824_9 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 597.0
HFD1_k127_5154486_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 9.168e-295 911.0
HFD1_k127_5154486_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 3.043e-208 654.0
HFD1_k127_5154486_2 - - - - 0.000000000000000000000000000000000000000000000000000001193 199.0
HFD1_k127_5154486_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000003016 170.0
HFD1_k127_5154486_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000004358 132.0
HFD1_k127_5154486_5 - - - - 0.0000000000000000000001197 102.0
HFD1_k127_5154486_6 KR domain - - - 0.000000000004231 69.0
HFD1_k127_5154486_7 - - - - 0.000008774 49.0
HFD1_k127_5161014_0 PFAM carboxyl transferase K01615 - 4.1.1.70 2.401e-287 890.0
HFD1_k127_5161014_1 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 552.0
HFD1_k127_5161014_2 TIGRFAM sodium ion-translocating decarboxylase, beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 547.0
HFD1_k127_5161014_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006104 253.0
HFD1_k127_5161014_4 Biotin-requiring enzyme K02160 - - 0.0000000000000000721 82.0
HFD1_k127_5164580_0 Acetyl-coenzyme A synthetase N-terminus K01895,K01908 GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224 6.2.1.1,6.2.1.17 0.0 1057.0
HFD1_k127_5164580_1 Oligopeptidase F K08602 - - 7.109e-303 938.0
HFD1_k127_5164580_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 587.0
HFD1_k127_5164580_11 Alanine dehydrogenase/PNT, C-terminal domain K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 580.0
HFD1_k127_5164580_12 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 581.0
HFD1_k127_5164580_13 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 561.0
HFD1_k127_5164580_14 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 537.0
HFD1_k127_5164580_15 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 539.0
HFD1_k127_5164580_16 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 536.0
HFD1_k127_5164580_17 Methionine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 504.0
HFD1_k127_5164580_18 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 503.0
HFD1_k127_5164580_19 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 455.0
HFD1_k127_5164580_2 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K02182 - 6.2.1.48 4.423e-299 923.0
HFD1_k127_5164580_20 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 434.0
HFD1_k127_5164580_21 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 441.0
HFD1_k127_5164580_22 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 411.0
HFD1_k127_5164580_23 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 407.0
HFD1_k127_5164580_24 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 397.0
HFD1_k127_5164580_25 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 403.0
HFD1_k127_5164580_26 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 385.0
HFD1_k127_5164580_27 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 373.0
HFD1_k127_5164580_28 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 353.0
HFD1_k127_5164580_29 Amidohydrolase family K01443 GO:0003674,GO:0003824,GO:0005488,GO:0006040,GO:0006044,GO:0006046,GO:0006054,GO:0006082,GO:0008150,GO:0008152,GO:0008270,GO:0008448,GO:0009056,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0016999,GO:0017001,GO:0017144,GO:0019213,GO:0019262,GO:0019752,GO:0022607,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046348,GO:0046395,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 355.0
HFD1_k127_5164580_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 1.17e-250 778.0
HFD1_k127_5164580_30 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 347.0
HFD1_k127_5164580_31 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 343.0
HFD1_k127_5164580_32 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 346.0
HFD1_k127_5164580_33 Major facilitator Superfamily K07165,K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 347.0
HFD1_k127_5164580_34 PFAM aldo keto reductase - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 336.0
HFD1_k127_5164580_35 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 331.0
HFD1_k127_5164580_36 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 329.0
HFD1_k127_5164580_37 PFAM sugar isomerase (SIS) K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 325.0
HFD1_k127_5164580_38 NADP oxidoreductase coenzyme F420-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 313.0
HFD1_k127_5164580_39 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 302.0
HFD1_k127_5164580_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.939e-230 721.0
HFD1_k127_5164580_40 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 306.0
HFD1_k127_5164580_41 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 288.0
HFD1_k127_5164580_42 Male sterility protein K01784,K19997 - 5.1.3.2,5.1.3.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002188 287.0
HFD1_k127_5164580_43 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002709 283.0
HFD1_k127_5164580_44 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004646 254.0
HFD1_k127_5164580_45 Protein of unknown function (DUF1036) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001675 240.0
HFD1_k127_5164580_46 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000002822 243.0
HFD1_k127_5164580_47 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000008892 238.0
HFD1_k127_5164580_48 nucleotide-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002829 229.0
HFD1_k127_5164580_49 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000004826 233.0
HFD1_k127_5164580_5 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 1.295e-229 736.0
HFD1_k127_5164580_50 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000007315 235.0
HFD1_k127_5164580_51 Function of homologous gene experimentally demonstrated in an other organism K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000005559 215.0
HFD1_k127_5164580_52 IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000007165 200.0
HFD1_k127_5164580_53 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.0000000000000000000000000000000000000000000000000000001574 198.0
HFD1_k127_5164580_54 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000002635 199.0
HFD1_k127_5164580_55 Function of homologous gene experimentally demonstrated in an other organism K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000005314 197.0
HFD1_k127_5164580_56 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000004168 182.0
HFD1_k127_5164580_57 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 0.0000000000000000000000000000000000000000000000000658 187.0
HFD1_k127_5164580_58 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000009537 177.0
HFD1_k127_5164580_59 - - - - 0.00000000000000000000000000000000000000000001166 171.0
HFD1_k127_5164580_6 ABC1 family - - - 2.809e-219 687.0
HFD1_k127_5164580_60 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000000000000000001969 160.0
HFD1_k127_5164580_61 - - - - 0.0000000000000000000000000000000000001873 147.0
HFD1_k127_5164580_62 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000002339 141.0
HFD1_k127_5164580_63 Belongs to the UPF0335 family - - - 0.00000000000000000000000000000002641 127.0
HFD1_k127_5164580_64 Protein of unknown function (DUF465) - - - 0.000000000000000000002643 96.0
HFD1_k127_5164580_65 Putative diguanylate phosphodiesterase - - - 0.000000000000000002031 93.0
HFD1_k127_5164580_66 Function of homologous gene experimentally demonstrated in an other organism K00433 - 1.11.1.10 0.000000000000000002679 85.0
HFD1_k127_5164580_67 Phasin protein - - - 0.000000000000000004197 86.0
HFD1_k127_5164580_68 Protein of unknown function (DUF465) - - - 0.000000000000001907 80.0
HFD1_k127_5164580_69 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000000533 76.0
HFD1_k127_5164580_7 Protein of unknown function (DUF1343) - - - 1.854e-218 682.0
HFD1_k127_5164580_70 Bacterial aa3 type cytochrome c oxidase subunit IV - - - 0.00000008257 58.0
HFD1_k127_5164580_72 CobN/Magnesium Chelatase K02230 - 6.6.1.2 0.000008002 54.0
HFD1_k127_5164580_73 Putative diguanylate phosphodiesterase - - - 0.00001041 48.0
HFD1_k127_5164580_74 - - - - 0.00001369 49.0
HFD1_k127_5164580_8 Sigma-54 interaction domain K10912 GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 3.889e-209 661.0
HFD1_k127_5164580_9 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 4.856e-206 661.0
HFD1_k127_5173511_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1399.0
HFD1_k127_5173511_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1266.0
HFD1_k127_5173511_10 PHB de-polymerase C-terminus K05973 - 3.1.1.75 7.236e-207 654.0
HFD1_k127_5173511_11 acyl-CoA dehydrogenase K00249 - 1.3.8.7 2.805e-204 640.0
HFD1_k127_5173511_12 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 563.0
HFD1_k127_5173511_13 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 554.0
HFD1_k127_5173511_14 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 534.0
HFD1_k127_5173511_15 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 525.0
HFD1_k127_5173511_16 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 512.0
HFD1_k127_5173511_17 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 510.0
HFD1_k127_5173511_18 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 503.0
HFD1_k127_5173511_19 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 498.0
HFD1_k127_5173511_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - 2.376e-310 965.0
HFD1_k127_5173511_20 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 482.0
HFD1_k127_5173511_21 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 458.0
HFD1_k127_5173511_22 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 464.0
HFD1_k127_5173511_23 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 456.0
HFD1_k127_5173511_24 Amidohydrolase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 452.0
HFD1_k127_5173511_25 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 442.0
HFD1_k127_5173511_26 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 420.0
HFD1_k127_5173511_27 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 415.0
HFD1_k127_5173511_28 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 407.0
HFD1_k127_5173511_29 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 401.0
HFD1_k127_5173511_3 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 3.816e-279 874.0
HFD1_k127_5173511_30 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 392.0
HFD1_k127_5173511_31 Major Facilitator Superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 387.0
HFD1_k127_5173511_32 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 374.0
HFD1_k127_5173511_33 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 378.0
HFD1_k127_5173511_34 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 373.0
HFD1_k127_5173511_35 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 357.0
HFD1_k127_5173511_36 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 354.0
HFD1_k127_5173511_37 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 343.0
HFD1_k127_5173511_38 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 340.0
HFD1_k127_5173511_39 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 285.0
HFD1_k127_5173511_4 phosphorylase activity K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 2.595e-267 830.0
HFD1_k127_5173511_40 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 292.0
HFD1_k127_5173511_41 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 285.0
HFD1_k127_5173511_42 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005064 278.0
HFD1_k127_5173511_43 Dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001284 264.0
HFD1_k127_5173511_44 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001043 244.0
HFD1_k127_5173511_45 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001794 237.0
HFD1_k127_5173511_46 DNA repair protein MmcB-like - - - 0.00000000000000000000000000000000000000000000000000000000000001113 222.0
HFD1_k127_5173511_47 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000009311 188.0
HFD1_k127_5173511_48 acyl-CoA dehydrogenase K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.0000000000000000000000000000000000000000003418 158.0
HFD1_k127_5173511_49 - - - - 0.000000000000000000000000000000000000000009977 163.0
HFD1_k127_5173511_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.758e-239 750.0
HFD1_k127_5173511_50 Protein of unknown function (DUF3237) - - - 0.0000000000000000000000000000000000000000652 158.0
HFD1_k127_5173511_51 Thioesterase superfamily K01075 - 3.1.2.23 0.000000000000000000000000000000000004152 145.0
HFD1_k127_5173511_52 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000001019 136.0
HFD1_k127_5173511_53 Patatin-like phospholipase K07001 - - 0.0000000000000000005752 87.0
HFD1_k127_5173511_6 AMP-binding enzyme K12508 - 6.2.1.34 5.977e-229 732.0
HFD1_k127_5173511_7 Flavin-binding monooxygenase-like K07222 - - 1.554e-213 677.0
HFD1_k127_5173511_8 Belongs to the thiolase family K07823 - 2.3.1.174 2.131e-208 657.0
HFD1_k127_5173511_9 ribosomal rna small subunit methyltransferase - - - 2.637e-207 654.0
HFD1_k127_5179861_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 570.0
HFD1_k127_5179861_1 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 328.0
HFD1_k127_5179861_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 316.0
HFD1_k127_5179861_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 291.0
HFD1_k127_5179861_4 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000000000000000001081 187.0
HFD1_k127_5179861_5 Phosphorylase superfamily - - - 0.000000000000000000000000000000000000000000000003146 175.0
HFD1_k127_5180530_0 Oxidoreductase - - - 5.421e-202 634.0
HFD1_k127_5180530_1 Protein of unknown function (DUF993) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 609.0
HFD1_k127_5180530_10 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000007068 222.0
HFD1_k127_5180530_11 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000001791 211.0
HFD1_k127_5180530_12 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.00003952 54.0
HFD1_k127_5180530_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 484.0
HFD1_k127_5180530_3 Protein of unknown function (DUF561) K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 481.0
HFD1_k127_5180530_4 Dihydrodipicolinate synthetase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 476.0
HFD1_k127_5180530_5 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 446.0
HFD1_k127_5180530_6 PFAM ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 376.0
HFD1_k127_5180530_7 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 360.0
HFD1_k127_5180530_8 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 346.0
HFD1_k127_5180530_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 317.0
HFD1_k127_5197745_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 623.0
HFD1_k127_5197745_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005112 276.0
HFD1_k127_5203280_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 5.64e-197 627.0
HFD1_k127_5203280_1 glycine cleavage system K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 506.0
HFD1_k127_5203280_10 Short C-terminal domain K08982 - - 0.0002377 46.0
HFD1_k127_5203280_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 475.0
HFD1_k127_5203280_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 315.0
HFD1_k127_5203280_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000002548 156.0
HFD1_k127_5203280_5 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000001384 139.0
HFD1_k127_5293992_0 ATPase (P-type) K01537,K12952 - 3.6.3.8 2.046e-297 938.0
HFD1_k127_5293992_1 LysR substrate binding domain K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000164 292.0
HFD1_k127_5293992_2 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000001421 125.0
HFD1_k127_5293992_3 Domain of unknown function (DUF1476) - - - 0.00000008603 61.0
HFD1_k127_5308442_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1708.0
HFD1_k127_5308442_1 Glycosyl transferase family 21 K00694,K01210 - 2.4.1.12,3.2.1.58 0.0 1274.0
HFD1_k127_5308442_10 beta (1-6) glucans synthase K01210 - 3.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 589.0
HFD1_k127_5308442_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 582.0
HFD1_k127_5308442_12 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 580.0
HFD1_k127_5308442_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 505.0
HFD1_k127_5308442_14 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 509.0
HFD1_k127_5308442_15 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 487.0
HFD1_k127_5308442_16 FAD binding domain K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 471.0
HFD1_k127_5308442_17 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 436.0
HFD1_k127_5308442_18 Aspartyl Asparaginyl beta-hydroxylase K00476,K12979 - 1.14.11.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 409.0
HFD1_k127_5308442_19 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 413.0
HFD1_k127_5308442_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 2.7e-322 1004.0
HFD1_k127_5308442_20 Alcohol dehydrogenase GroES-like domain K00055 - 1.1.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 389.0
HFD1_k127_5308442_21 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 351.0
HFD1_k127_5308442_22 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 302.0
HFD1_k127_5308442_23 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 304.0
HFD1_k127_5308442_24 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 289.0
HFD1_k127_5308442_25 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005762 285.0
HFD1_k127_5308442_26 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000057 287.0
HFD1_k127_5308442_27 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001672 270.0
HFD1_k127_5308442_28 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001528 275.0
HFD1_k127_5308442_29 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004032 268.0
HFD1_k127_5308442_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.371e-296 920.0
HFD1_k127_5308442_30 Invasion associated locus B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009332 259.0
HFD1_k127_5308442_31 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001273 254.0
HFD1_k127_5308442_32 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000146 253.0
HFD1_k127_5308442_33 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.0000000000000000000000000000000000000000000000000000000000000000000000028 250.0
HFD1_k127_5308442_34 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000001102 231.0
HFD1_k127_5308442_35 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000009996 209.0
HFD1_k127_5308442_36 - - - - 0.0000000000000000000000000000000000000000000000000006925 189.0
HFD1_k127_5308442_37 Hemimethylated DNA-binding protein YccV like K11940 - - 0.000000000000000000000000000000000000000000000008932 175.0
HFD1_k127_5308442_38 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000002501 161.0
HFD1_k127_5308442_39 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000000002311 120.0
HFD1_k127_5308442_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.498e-259 814.0
HFD1_k127_5308442_40 GGDEF domain - - - 0.000000000000000000002411 100.0
HFD1_k127_5308442_41 Urate oxidase N-terminal - - - 0.000000000000004509 77.0
HFD1_k127_5308442_42 Tfp pilus assembly protein FimV - - - 0.00000000000003001 83.0
HFD1_k127_5308442_43 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000001063 71.0
HFD1_k127_5308442_44 Phage integrase family - - - 0.00003848 52.0
HFD1_k127_5308442_45 AMP-binding enzyme - - - 0.0004591 45.0
HFD1_k127_5308442_46 - - - - 0.0006436 46.0
HFD1_k127_5308442_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.569e-259 809.0
HFD1_k127_5308442_6 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.824e-240 748.0
HFD1_k127_5308442_7 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.134e-236 741.0
HFD1_k127_5308442_8 HpcH/HpaI aldolase/citrate lyase family K08691 GO:0003674,GO:0003824,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872,GO:0047777,GO:0050083 4.1.3.24,4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 601.0
HFD1_k127_5308442_9 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 587.0
HFD1_k127_5343716_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.045e-228 712.0
HFD1_k127_5343716_1 Methyltransferase fkbm family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 406.0
HFD1_k127_5343716_2 HNH nucleases K07451 - - 0.000000000000000000000002994 105.0
HFD1_k127_5343716_3 Phage terminase-like protein large subunit - - - 0.0000000000468 64.0
HFD1_k127_5402015_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.627e-252 788.0
HFD1_k127_5402015_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 7.314e-210 658.0
HFD1_k127_5402015_10 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 479.0
HFD1_k127_5402015_11 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 460.0
HFD1_k127_5402015_12 Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 438.0
HFD1_k127_5402015_13 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 426.0
HFD1_k127_5402015_14 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 404.0
HFD1_k127_5402015_15 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 363.0
HFD1_k127_5402015_16 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 369.0
HFD1_k127_5402015_17 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 334.0
HFD1_k127_5402015_18 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 324.0
HFD1_k127_5402015_19 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 318.0
HFD1_k127_5402015_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.071e-204 645.0
HFD1_k127_5402015_20 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001429 281.0
HFD1_k127_5402015_21 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000002702 203.0
HFD1_k127_5402015_22 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000007945 155.0
HFD1_k127_5402015_23 Protein of unknown function (DUF3775) - - - 0.00000000000000000000000000000000003327 138.0
HFD1_k127_5402015_24 Resolvase, N terminal domain K06400 - - 0.00000000000000000000000000000000008295 137.0
HFD1_k127_5402015_25 Integrase - - - 0.00000000000000000000000000003598 121.0
HFD1_k127_5402015_26 Cobalamin synthesis protein P47K - - - 0.000000000000000006946 84.0
HFD1_k127_5402015_27 Integrase - - - 0.0000000000009871 68.0
HFD1_k127_5402015_28 Belongs to the bacterial histone-like protein family K03530 - - 0.00000000002528 64.0
HFD1_k127_5402015_29 3'-5' exonuclease K07501 - - 0.000007034 51.0
HFD1_k127_5402015_3 Adenylate cyclase - - - 1.864e-198 635.0
HFD1_k127_5402015_4 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 590.0
HFD1_k127_5402015_5 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 563.0
HFD1_k127_5402015_6 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 539.0
HFD1_k127_5402015_7 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 490.0
HFD1_k127_5402015_8 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 494.0
HFD1_k127_5402015_9 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 505.0
HFD1_k127_5412767_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1464.0
HFD1_k127_5412767_1 Amidohydrolase family K01465 - 3.5.2.3 1.092e-233 728.0
HFD1_k127_5412767_10 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 391.0
HFD1_k127_5412767_11 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 359.0
HFD1_k127_5412767_12 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 347.0
HFD1_k127_5412767_13 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 335.0
HFD1_k127_5412767_14 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 329.0
HFD1_k127_5412767_15 glycosylase i K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 322.0
HFD1_k127_5412767_16 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 291.0
HFD1_k127_5412767_17 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 294.0
HFD1_k127_5412767_18 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008586 278.0
HFD1_k127_5412767_19 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004624 249.0
HFD1_k127_5412767_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 7.299e-205 644.0
HFD1_k127_5412767_20 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000001266 234.0
HFD1_k127_5412767_21 protein tyrosine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000002405 215.0
HFD1_k127_5412767_22 Protein of unknown function (DUF2385) - - - 0.00000000000000000000000000000000000000000000000000007582 189.0
HFD1_k127_5412767_23 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000007121 185.0
HFD1_k127_5412767_24 - - - - 0.00000000000000000000000000000000000000000000006432 173.0
HFD1_k127_5412767_25 Isochorismatase family - - - 0.00000000000000000000000000000000000000000002647 169.0
HFD1_k127_5412767_26 NUDIX domain - - - 0.00000000000000000000000000000000000000000003211 169.0
HFD1_k127_5412767_27 Cupredoxin-like domain - - - 0.0000000000000000000000000000000002824 135.0
HFD1_k127_5412767_28 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000004796 135.0
HFD1_k127_5412767_29 - - - - 0.000000000000000000000000000002678 122.0
HFD1_k127_5412767_3 FAD linked oxidases, C-terminal domain K00102 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 6.425e-197 623.0
HFD1_k127_5412767_30 - - - - 0.000000000000003968 79.0
HFD1_k127_5412767_31 - - - - 0.00000000002627 67.0
HFD1_k127_5412767_32 Protein of unknown function (DUF3096) - - - 0.0000000009743 61.0
HFD1_k127_5412767_34 - - - - 0.0002224 46.0
HFD1_k127_5412767_35 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0003034 46.0
HFD1_k127_5412767_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 542.0
HFD1_k127_5412767_5 Zinc-binding dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 500.0
HFD1_k127_5412767_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 495.0
HFD1_k127_5412767_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 455.0
HFD1_k127_5412767_8 Cell Wall Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 418.0
HFD1_k127_5412767_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 406.0
HFD1_k127_5417841_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 3.674e-216 692.0
HFD1_k127_5417841_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 567.0
HFD1_k127_5417841_10 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000000000000000004836 197.0
HFD1_k127_5417841_11 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000001417 200.0
HFD1_k127_5417841_12 - - - - 0.000000000000000000000000005485 115.0
HFD1_k127_5417841_13 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000003935 111.0
HFD1_k127_5417841_14 FAD binding domain - - - 0.0000000000002228 70.0
HFD1_k127_5417841_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 459.0
HFD1_k127_5417841_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 396.0
HFD1_k127_5417841_4 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 331.0
HFD1_k127_5417841_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004013 281.0
HFD1_k127_5417841_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001795 250.0
HFD1_k127_5417841_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000431 258.0
HFD1_k127_5417841_8 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000009922 227.0
HFD1_k127_5417841_9 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000001739 226.0
HFD1_k127_548934_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 1.521e-283 880.0
HFD1_k127_548934_1 acyl-CoA dehydrogenase K00252 - 1.3.8.6 8.428e-196 616.0
HFD1_k127_548934_10 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000001873 119.0
HFD1_k127_548934_11 oxygen carrier activity K07216 - - 0.0000000000000000008594 88.0
HFD1_k127_548934_12 - - - - 0.000000000000001662 78.0
HFD1_k127_548934_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 599.0
HFD1_k127_548934_3 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 336.0
HFD1_k127_548934_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000219 288.0
HFD1_k127_548934_5 cytochrome c oxidase (Subunit II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003896 276.0
HFD1_k127_548934_6 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000035 244.0
HFD1_k127_548934_7 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K13642 - - 0.00000000000000000000000000000000000000000000000000003025 196.0
HFD1_k127_548934_8 - - - - 0.000000000000000000000000000000000004735 141.0
HFD1_k127_548934_9 - - - - 0.0000000000000000000000000000000001156 145.0
HFD1_k127_5535352_0 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 326.0
HFD1_k127_5535352_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001938 229.0
HFD1_k127_5535352_2 - - - - 0.000000000000000000000000000000000000000000000000000000008006 205.0
HFD1_k127_5535352_3 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000006167 110.0
HFD1_k127_5535352_4 Rhodanese Homology Domain - - - 0.00000000000000000005438 91.0
HFD1_k127_555469_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0 1293.0
HFD1_k127_555469_1 Helicase associated domain (HA2) Add an annotation K03579 - 3.6.4.13 0.0 1109.0
HFD1_k127_555469_10 Acetyl-coenzyme A transporter 1 K08218 - - 2.349e-200 634.0
HFD1_k127_555469_11 Acyl-CoA dehydrogenase, C-terminal domain K19966 - 3.13.1.4 1.227e-197 622.0
HFD1_k127_555469_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 612.0
HFD1_k127_555469_13 N-terminal TM domain of oligopeptide transport permease C K13895 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 583.0
HFD1_k127_555469_14 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 575.0
HFD1_k127_555469_15 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 567.0
HFD1_k127_555469_16 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 534.0
HFD1_k127_555469_17 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 497.0
HFD1_k127_555469_18 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 485.0
HFD1_k127_555469_19 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 464.0
HFD1_k127_555469_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 4.703e-295 916.0
HFD1_k127_555469_20 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 456.0
HFD1_k127_555469_21 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 447.0
HFD1_k127_555469_22 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 437.0
HFD1_k127_555469_23 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 403.0
HFD1_k127_555469_24 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 389.0
HFD1_k127_555469_25 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 367.0
HFD1_k127_555469_26 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 353.0
HFD1_k127_555469_27 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 347.0
HFD1_k127_555469_28 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 346.0
HFD1_k127_555469_29 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 327.0
HFD1_k127_555469_3 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 6.506e-284 885.0
HFD1_k127_555469_30 Cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 305.0
HFD1_k127_555469_31 PFAM glycosyl transferase family 9 K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003933 285.0
HFD1_k127_555469_32 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003807 269.0
HFD1_k127_555469_33 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002265 261.0
HFD1_k127_555469_34 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000001985 253.0
HFD1_k127_555469_35 Belongs to the carbohydrate kinase PfkB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005235 256.0
HFD1_k127_555469_36 Cytochrome c K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001169 261.0
HFD1_k127_555469_37 helix_turn_helix ASNC type K05800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003579 245.0
HFD1_k127_555469_38 SNARE associated golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000004087 211.0
HFD1_k127_555469_39 PFAM DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000004219 206.0
HFD1_k127_555469_4 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 9.01e-284 878.0
HFD1_k127_555469_40 methyl-accepting chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000008499 203.0
HFD1_k127_555469_41 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000001124 184.0
HFD1_k127_555469_42 HIT domain - - - 0.0000000000000000000000000000000000000000000000001408 181.0
HFD1_k127_555469_43 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000007625 174.0
HFD1_k127_555469_44 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000004188 165.0
HFD1_k127_555469_45 HupE / UreJ protein K03192 - - 0.0000000000000000000000000000000000000000004131 165.0
HFD1_k127_555469_46 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000008566 149.0
HFD1_k127_555469_47 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000000011 150.0
HFD1_k127_555469_48 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.0000000000000000000000000000000000003623 151.0
HFD1_k127_555469_49 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000003894 130.0
HFD1_k127_555469_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.776e-279 870.0
HFD1_k127_555469_50 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000006561 126.0
HFD1_k127_555469_51 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000003177 76.0
HFD1_k127_555469_52 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000001339 56.0
HFD1_k127_555469_53 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000005885 53.0
HFD1_k127_555469_54 synthase K16167 - - 0.000009181 51.0
HFD1_k127_555469_55 - - - - 0.0005555 44.0
HFD1_k127_555469_6 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 8.203e-279 863.0
HFD1_k127_555469_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 4.395e-237 749.0
HFD1_k127_555469_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 3.445e-221 691.0
HFD1_k127_555469_9 Binding-protein-dependent transport system inner membrane component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 1.81e-200 629.0
HFD1_k127_5642893_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1668.0
HFD1_k127_5642893_1 MMPL family K03296 - - 0.0 1484.0
HFD1_k127_5642893_10 beta-1,4-mannooligosaccharide phosphorylase - - - 4.475e-225 703.0
HFD1_k127_5642893_11 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein - - - 7.298e-208 661.0
HFD1_k127_5642893_12 Tripartite tricarboxylate transporter TctA family K07793 - - 4.394e-201 641.0
HFD1_k127_5642893_13 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.794e-197 624.0
HFD1_k127_5642893_14 Rieske [2Fe-2S] domain - - - 3.407e-194 614.0
HFD1_k127_5642893_15 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 537.0
HFD1_k127_5642893_16 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 533.0
HFD1_k127_5642893_17 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 530.0
HFD1_k127_5642893_18 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 522.0
HFD1_k127_5642893_19 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 497.0
HFD1_k127_5642893_2 AcrB/AcrD/AcrF family K21134 - - 0.0 1479.0
HFD1_k127_5642893_20 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 458.0
HFD1_k127_5642893_21 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 452.0
HFD1_k127_5642893_22 Cellulose biosynthesis protein BcsQ K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 436.0
HFD1_k127_5642893_23 Oxidoreductase family, C-terminal alpha/beta domain K18067 - 1.3.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 435.0
HFD1_k127_5642893_24 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 420.0
HFD1_k127_5642893_25 Amidohydrolase K10221 - 3.1.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 417.0
HFD1_k127_5642893_26 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 418.0
HFD1_k127_5642893_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 408.0
HFD1_k127_5642893_28 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 393.0
HFD1_k127_5642893_29 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 378.0
HFD1_k127_5642893_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1413.0
HFD1_k127_5642893_30 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 374.0
HFD1_k127_5642893_31 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 365.0
HFD1_k127_5642893_32 2-keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 361.0
HFD1_k127_5642893_33 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 357.0
HFD1_k127_5642893_34 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 345.0
HFD1_k127_5642893_35 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 342.0
HFD1_k127_5642893_36 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 333.0
HFD1_k127_5642893_37 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 333.0
HFD1_k127_5642893_38 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 340.0
HFD1_k127_5642893_39 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 317.0
HFD1_k127_5642893_4 Glycosyl transferases group 1 - - - 0.0 1045.0
HFD1_k127_5642893_40 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 313.0
HFD1_k127_5642893_41 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K09565 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 288.0
HFD1_k127_5642893_42 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 285.0
HFD1_k127_5642893_43 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 286.0
HFD1_k127_5642893_44 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001349 274.0
HFD1_k127_5642893_45 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 260.0
HFD1_k127_5642893_46 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001808 254.0
HFD1_k127_5642893_47 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001203 254.0
HFD1_k127_5642893_48 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000134 247.0
HFD1_k127_5642893_49 PFAM MaoC domain protein dehydratase K17865 GO:0003674,GO:0003824,GO:0003859,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0046487,GO:0071704 4.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000004187 246.0
HFD1_k127_5642893_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0 1013.0
HFD1_k127_5642893_50 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000156 253.0
HFD1_k127_5642893_51 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006477 245.0
HFD1_k127_5642893_52 Phytoene squalene synthetase K02291,K18163 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000001417 236.0
HFD1_k127_5642893_53 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000006905 236.0
HFD1_k127_5642893_54 response to abiotic stimulus K06867 GO:0008150,GO:0009314,GO:0009628,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000009239 230.0
HFD1_k127_5642893_55 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000000000000000001293 223.0
HFD1_k127_5642893_56 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000005778 216.0
HFD1_k127_5642893_57 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000009289 198.0
HFD1_k127_5642893_58 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000000000000000001728 190.0
HFD1_k127_5642893_59 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000001759 194.0
HFD1_k127_5642893_6 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.0 998.0
HFD1_k127_5642893_60 Belongs to the HesB IscA family K13628,K15724 - - 0.000000000000000000000000000000000000000000000000101 179.0
HFD1_k127_5642893_61 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000001134 184.0
HFD1_k127_5642893_62 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002735 182.0
HFD1_k127_5642893_63 - - - - 0.000000000000000000000000000000000000000000000007 179.0
HFD1_k127_5642893_64 - - - - 0.00000000000000000000000000000000000000000002429 173.0
HFD1_k127_5642893_65 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000008119 152.0
HFD1_k127_5642893_66 LysE type translocator - - - 0.0000000000000000000000000000000000000000884 158.0
HFD1_k127_5642893_67 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000001007 153.0
HFD1_k127_5642893_68 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000001449 156.0
HFD1_k127_5642893_7 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.748e-276 864.0
HFD1_k127_5642893_70 SPW repeat - - - 0.00000000000000000000000000000000000006242 147.0
HFD1_k127_5642893_71 Methyltransferase domain - - - 0.000000000000000000000000000000000002299 143.0
HFD1_k127_5642893_72 Response regulator receiver - - - 0.000000000000000000000000000000000002553 141.0
HFD1_k127_5642893_73 - - - - 0.0000000000000000000000000000000001131 139.0
HFD1_k127_5642893_74 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000001557 133.0
HFD1_k127_5642893_75 antibiotic catabolic process - - - 0.0000000000000000000000000000004201 130.0
HFD1_k127_5642893_76 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000008555 126.0
HFD1_k127_5642893_77 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.000000000000000000000000000001125 126.0
HFD1_k127_5642893_78 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000004442 122.0
HFD1_k127_5642893_79 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000000001794 118.0
HFD1_k127_5642893_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 2.028e-274 851.0
HFD1_k127_5642893_80 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000000000000004087 111.0
HFD1_k127_5642893_81 Pfam Transposase IS66 - - - 0.0000000000000000000000002221 121.0
HFD1_k127_5642893_82 - - - - 0.00000000000000000000001151 104.0
HFD1_k127_5642893_83 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000004279 103.0
HFD1_k127_5642893_84 Dodecin K09165 - - 0.00000000000000000000004855 100.0
HFD1_k127_5642893_85 Protein of unknown function (DUF1488) - - - 0.0000000000000000000001754 101.0
HFD1_k127_5642893_86 - - - - 0.0000000000000000000007009 98.0
HFD1_k127_5642893_87 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.000000000000000000001064 96.0
HFD1_k127_5642893_88 - - - - 0.00000000000000000004277 104.0
HFD1_k127_5642893_89 - - - - 0.000000000000000002264 91.0
HFD1_k127_5642893_9 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 4.283e-227 712.0
HFD1_k127_5642893_90 Histidine kinase - - - 0.000000000000004375 82.0
HFD1_k127_5642893_91 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000006292 80.0
HFD1_k127_5642893_93 Domain of unknown function (DUF1127) - - - 0.00000000009301 63.0
HFD1_k127_5642893_94 - - - - 0.000000005777 59.0
HFD1_k127_5642893_95 - - - - 0.0000000588 56.0
HFD1_k127_5674838_0 Hydrolase CocE NonD family K06978 - - 5.221e-289 896.0
HFD1_k127_5674838_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 387.0
HFD1_k127_5674838_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001489 251.0
HFD1_k127_5674838_11 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005583 250.0
HFD1_k127_5674838_12 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000178 248.0
HFD1_k127_5674838_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 339.0
HFD1_k127_5674838_3 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 316.0
HFD1_k127_5674838_4 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 313.0
HFD1_k127_5674838_5 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 316.0
HFD1_k127_5674838_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 312.0
HFD1_k127_5674838_7 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004256 278.0
HFD1_k127_5674838_8 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002636 273.0
HFD1_k127_5674838_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006059 254.0
HFD1_k127_5683079_0 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 505.0
HFD1_k127_5683079_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 501.0
HFD1_k127_5683079_2 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 409.0
HFD1_k127_5683079_3 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 331.0
HFD1_k127_5683079_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001044 273.0
HFD1_k127_5683079_5 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000000006516 186.0
HFD1_k127_5683079_6 Hypoxia induced protein conserved region - - - 0.0000000000000000000002562 97.0
HFD1_k127_5683079_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000001126 71.0
HFD1_k127_5751993_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 427.0
HFD1_k127_5751993_1 thiamine-containing compound biosynthetic process K02051 - - 0.000006772 52.0
HFD1_k127_576801_0 Prokaryotic glutathione synthetase, N-terminal domain K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 504.0
HFD1_k127_576801_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 468.0
HFD1_k127_576801_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000001722 126.0
HFD1_k127_576801_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000002707 79.0
HFD1_k127_576801_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000000003819 68.0
HFD1_k127_5770417_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 4.736e-224 703.0
HFD1_k127_5770417_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 585.0
HFD1_k127_5770417_2 PFAM Carbohydrate-selective porin OprB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 442.0
HFD1_k127_5770417_3 Cupredoxin-like domain - - - 0.0000000000000000000000000008109 119.0
HFD1_k127_5770417_4 Membrane fusogenic activity K09806 - - 0.00000000000000000000007406 101.0
HFD1_k127_5877351_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 479.0
HFD1_k127_5877351_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 400.0
HFD1_k127_5877351_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 376.0
HFD1_k127_5877351_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 337.0
HFD1_k127_5877351_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000001363 226.0
HFD1_k127_5877351_5 Sterol carrier protein - - - 0.000000000000000009947 88.0
HFD1_k127_5885981_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1899.0
HFD1_k127_5885981_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1103.0
HFD1_k127_5885981_10 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 461.0
HFD1_k127_5885981_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 445.0
HFD1_k127_5885981_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 440.0
HFD1_k127_5885981_13 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 422.0
HFD1_k127_5885981_14 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 425.0
HFD1_k127_5885981_15 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 424.0
HFD1_k127_5885981_16 Catechol dioxygenase N terminus K03381 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006725,GO:0008150,GO:0008152,GO:0008199,GO:0009056,GO:0009712,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0018576,GO:0018958,GO:0019114,GO:0019336,GO:0019439,GO:0019614,GO:0019615,GO:0042952,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 1.13.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 418.0
HFD1_k127_5885981_17 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 422.0
HFD1_k127_5885981_18 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 384.0
HFD1_k127_5885981_19 Extensin-like protein C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 369.0
HFD1_k127_5885981_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.258e-308 957.0
HFD1_k127_5885981_20 transcriptional regulator, winged helix family K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 354.0
HFD1_k127_5885981_21 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 340.0
HFD1_k127_5885981_22 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 341.0
HFD1_k127_5885981_23 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 330.0
HFD1_k127_5885981_24 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 316.0
HFD1_k127_5885981_25 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 305.0
HFD1_k127_5885981_26 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 292.0
HFD1_k127_5885981_27 Belongs to the RNase T2 family K01166,K01169 - 3.1.27.1,3.1.27.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 288.0
HFD1_k127_5885981_28 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 283.0
HFD1_k127_5885981_29 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 288.0
HFD1_k127_5885981_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07638 - 2.7.13.3 1.426e-234 734.0
HFD1_k127_5885981_30 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001199 281.0
HFD1_k127_5885981_31 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006373 283.0
HFD1_k127_5885981_32 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 277.0
HFD1_k127_5885981_33 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002328 273.0
HFD1_k127_5885981_34 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001924 254.0
HFD1_k127_5885981_35 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000066 250.0
HFD1_k127_5885981_36 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004594 248.0
HFD1_k127_5885981_37 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006034 246.0
HFD1_k127_5885981_38 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002015 248.0
HFD1_k127_5885981_39 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
HFD1_k127_5885981_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 1.491e-194 611.0
HFD1_k127_5885981_40 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000001703 218.0
HFD1_k127_5885981_41 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000004587 217.0
HFD1_k127_5885981_42 Tryptophan-rich sensory protein K05770 - - 0.000000000000000000000000000000000000000000000000000000000003087 220.0
HFD1_k127_5885981_43 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001503 205.0
HFD1_k127_5885981_44 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000008359 196.0
HFD1_k127_5885981_45 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000000000000004171 186.0
HFD1_k127_5885981_46 - - - - 0.0000000000000000000000000000000000000000000000009344 178.0
HFD1_k127_5885981_47 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000000004154 141.0
HFD1_k127_5885981_48 - - - - 0.00000000000000000000000000000000005523 145.0
HFD1_k127_5885981_49 - - - - 0.0000000000000000000000000000000005513 134.0
HFD1_k127_5885981_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 572.0
HFD1_k127_5885981_50 Domain of unknown function (DUF4403) - - - 0.000000000000000000000000000000003637 137.0
HFD1_k127_5885981_51 Membrane fusogenic activity K09806 - - 0.0000000000000000000000000000000306 129.0
HFD1_k127_5885981_52 Domain of Unknown Function (DUF930) - - - 0.0000000000000000000000000000001401 128.0
HFD1_k127_5885981_53 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.0000000000000000000000000000002184 127.0
HFD1_k127_5885981_54 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000000000006781 126.0
HFD1_k127_5885981_55 - - - - 0.0000000000000000000000000001387 120.0
HFD1_k127_5885981_56 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000006067 99.0
HFD1_k127_5885981_57 Domain of unknown function DUF123 - - - 0.000000000000000000002741 96.0
HFD1_k127_5885981_58 - - - - 0.00000000000000000002017 96.0
HFD1_k127_5885981_59 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000001558 87.0
HFD1_k127_5885981_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 538.0
HFD1_k127_5885981_60 Protein of unknown function (DUF1460) - - - 0.0000000000000006251 88.0
HFD1_k127_5885981_61 Domain of unknown function (DUF4403) - - - 0.00000000000007554 79.0
HFD1_k127_5885981_63 membrane protein (DUF2078) K08982 - - 0.000009178 50.0
HFD1_k127_5885981_64 Excinuclease ABC, C subunit K07461 - - 0.0001618 50.0
HFD1_k127_5885981_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 519.0
HFD1_k127_5885981_8 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 493.0
HFD1_k127_5885981_9 arsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 479.0
HFD1_k127_5891957_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0 1266.0
HFD1_k127_5891957_1 Thiamine pyrophosphate enzyme, central domain - - - 3.873e-291 903.0
HFD1_k127_5891957_2 Periplasmic binding protein K01999 - - 3.305e-227 708.0
HFD1_k127_5891957_3 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 559.0
HFD1_k127_5891957_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 549.0
HFD1_k127_5891957_5 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 462.0
HFD1_k127_5891957_6 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 398.0
HFD1_k127_5891957_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 355.0
HFD1_k127_5891957_8 Antibiotic biosynthesis monooxygenase - - - 0.000000000000004878 79.0
HFD1_k127_5909991_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 3.187e-264 835.0
HFD1_k127_5909991_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 6.349e-259 807.0
HFD1_k127_5909991_10 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 443.0
HFD1_k127_5909991_11 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 374.0
HFD1_k127_5909991_12 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 359.0
HFD1_k127_5909991_13 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 321.0
HFD1_k127_5909991_14 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 291.0
HFD1_k127_5909991_15 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001601 287.0
HFD1_k127_5909991_16 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005358 266.0
HFD1_k127_5909991_17 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001058 257.0
HFD1_k127_5909991_18 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006393 252.0
HFD1_k127_5909991_19 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000000000111 210.0
HFD1_k127_5909991_2 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 3.704e-246 769.0
HFD1_k127_5909991_20 methyl-accepting chemotaxis - - - 0.00000000000000000000000000000000000000000000000005118 197.0
HFD1_k127_5909991_21 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000006954 177.0
HFD1_k127_5909991_22 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000003524 165.0
HFD1_k127_5909991_23 Heavy-metal resistance - - - 0.000000000000005063 81.0
HFD1_k127_5909991_24 Polysaccharide biosynthesis protein - - - 0.00000001252 59.0
HFD1_k127_5909991_25 Polysaccharide biosynthesis protein - - - 0.000006541 53.0
HFD1_k127_5909991_26 - - - - 0.00002357 51.0
HFD1_k127_5909991_3 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 1.977e-221 700.0
HFD1_k127_5909991_4 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 572.0
HFD1_k127_5909991_5 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 554.0
HFD1_k127_5909991_6 PFAM monooxygenase FAD-binding K20940 - 1.14.13.218 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 552.0
HFD1_k127_5909991_7 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 529.0
HFD1_k127_5909991_8 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 499.0
HFD1_k127_5909991_9 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 471.0
HFD1_k127_5927444_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1196.0
HFD1_k127_5927444_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1088.0
HFD1_k127_5927444_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941,K18824 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 382.0
HFD1_k127_5927444_11 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 360.0
HFD1_k127_5927444_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 325.0
HFD1_k127_5927444_13 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 291.0
HFD1_k127_5927444_14 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001414 267.0
HFD1_k127_5927444_15 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000002022 268.0
HFD1_k127_5927444_16 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
HFD1_k127_5927444_17 Putative zinc- or iron-chelating domain K09160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008755 252.0
HFD1_k127_5927444_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000001258 237.0
HFD1_k127_5927444_19 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
HFD1_k127_5927444_2 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 2.275e-223 708.0
HFD1_k127_5927444_20 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids - - - 0.0000000000000000000000000000000000000000000000000000000000002035 220.0
HFD1_k127_5927444_21 Fe-S metabolism associated domain K02426 - - 0.00000000000000000000000000000000000000000000000000000000001324 209.0
HFD1_k127_5927444_22 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000000000000001714 192.0
HFD1_k127_5927444_23 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000002968 178.0
HFD1_k127_5927444_24 Protein of unknown function (DUF1491) - - - 0.000000000000000000000000000000000000000000002082 167.0
HFD1_k127_5927444_25 Domain of unknown function (DUF4332) - - - 0.0000000000000000000000000000000000000000004249 162.0
HFD1_k127_5927444_26 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000001206 154.0
HFD1_k127_5927444_27 His Kinase A (phosphoacceptor) domain K07716,K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000001648 155.0
HFD1_k127_5927444_28 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000004074 149.0
HFD1_k127_5927444_29 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000009296 151.0
HFD1_k127_5927444_3 Peptidase dimerisation domain K01436 - - 6.722e-204 643.0
HFD1_k127_5927444_30 Haem-degrading - - - 0.000000000000000000000000000000000001499 144.0
HFD1_k127_5927444_31 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000000002031 142.0
HFD1_k127_5927444_32 - - - - 0.00000000000000000000000000000000001646 138.0
HFD1_k127_5927444_33 - - - - 0.00000000000000000000000000000004624 132.0
HFD1_k127_5927444_34 Family of unknown function (DUF5330) - - - 0.000000000000000000000001125 108.0
HFD1_k127_5927444_35 - - - - 0.00000000000000000000001898 111.0
HFD1_k127_5927444_36 Bacterial dnaA protein helix-turn-helix - - - 0.00000000000000000001913 95.0
HFD1_k127_5927444_37 Transposase - - - 0.000000001481 60.0
HFD1_k127_5927444_38 - - - - 0.000000004404 60.0
HFD1_k127_5927444_39 - - - - 0.000003318 52.0
HFD1_k127_5927444_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 4.037e-194 620.0
HFD1_k127_5927444_5 Histidine kinase K07716,K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 505.0
HFD1_k127_5927444_6 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 500.0
HFD1_k127_5927444_7 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 485.0
HFD1_k127_5927444_8 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 460.0
HFD1_k127_5927444_9 transport, permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 415.0
HFD1_k127_6025538_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.026e-242 757.0
HFD1_k127_6025538_1 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 568.0
HFD1_k127_6025538_10 Major facilitator superfamily - - - 0.000000578 54.0
HFD1_k127_6025538_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 416.0
HFD1_k127_6025538_3 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 407.0
HFD1_k127_6025538_4 NAD dependent epimerase/dehydratase family K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 373.0
HFD1_k127_6025538_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 316.0
HFD1_k127_6025538_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 318.0
HFD1_k127_6025538_7 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001185 282.0
HFD1_k127_6025538_8 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007591 261.0
HFD1_k127_6025538_9 Protease inhibitor Inh - - - 0.0000000000000000000000000000000000000000000000000007746 192.0
HFD1_k127_6076604_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 388.0
HFD1_k127_6076604_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 371.0
HFD1_k127_6083952_0 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 553.0
HFD1_k127_6083952_1 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 551.0
HFD1_k127_6083952_10 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 379.0
HFD1_k127_6083952_11 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 376.0
HFD1_k127_6083952_12 Coenzyme A transferase K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 370.0
HFD1_k127_6083952_13 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 351.0
HFD1_k127_6083952_14 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 336.0
HFD1_k127_6083952_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 313.0
HFD1_k127_6083952_16 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.0000000000000000000000000000000000000000000000000000000000000002242 228.0
HFD1_k127_6083952_17 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000001465 210.0
HFD1_k127_6083952_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.000000000000000000000000005329 112.0
HFD1_k127_6083952_19 Cytochrome c - - - 0.0000000000000000000000002609 111.0
HFD1_k127_6083952_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 500.0
HFD1_k127_6083952_21 EamA-like transporter family - - - 0.00000000006239 63.0
HFD1_k127_6083952_22 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000033 57.0
HFD1_k127_6083952_23 - - - - 0.000003332 56.0
HFD1_k127_6083952_3 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 495.0
HFD1_k127_6083952_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 473.0
HFD1_k127_6083952_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 434.0
HFD1_k127_6083952_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 417.0
HFD1_k127_6083952_7 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 392.0
HFD1_k127_6083952_8 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 384.0
HFD1_k127_6083952_9 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 382.0
HFD1_k127_6095396_0 Protein of unknown function (DUF2914) - - - 0.0000000000000000083 91.0
HFD1_k127_6095396_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.00000000000008932 81.0
HFD1_k127_6098582_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 5.826e-267 827.0
HFD1_k127_6098582_1 ABC transporter K02471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 606.0
HFD1_k127_6098582_2 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 605.0
HFD1_k127_6098582_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 597.0
HFD1_k127_6098582_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 512.0
HFD1_k127_6098582_5 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 466.0
HFD1_k127_6098582_6 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 311.0
HFD1_k127_6098582_7 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000005459 179.0
HFD1_k127_621795_0 CoA-transferase family III - - - 2.049e-201 637.0
HFD1_k127_621795_1 Belongs to the PdxA family K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 386.0
HFD1_k127_621795_2 FCD K11475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 338.0
HFD1_k127_621795_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 319.0
HFD1_k127_621795_4 Transposase - - - 0.0000000000000004259 78.0
HFD1_k127_6224688_0 Cys/Met metabolism PLP-dependent enzyme K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 5.76e-243 755.0
HFD1_k127_6224688_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 442.0
HFD1_k127_6224688_10 Protein of unknown function (DUF1236) - - - 0.0000000000000000000000003405 108.0
HFD1_k127_6224688_11 Protein of unknown function (DUF2842) - - - 0.00000000000000000001793 92.0
HFD1_k127_6224688_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 416.0
HFD1_k127_6224688_3 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 358.0
HFD1_k127_6224688_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 311.0
HFD1_k127_6224688_5 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000001707 249.0
HFD1_k127_6224688_6 Pfam:Pyridox_oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000001033 231.0
HFD1_k127_6224688_7 - - - - 0.0000000000000000000000000000000000000000000001066 172.0
HFD1_k127_6224688_8 Thioesterase superfamily - - - 0.000000000000000000000000000000000002784 141.0
HFD1_k127_6224688_9 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000002855 108.0
HFD1_k127_6263125_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.287e-208 652.0
HFD1_k127_6263125_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 531.0
HFD1_k127_6263125_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002383 286.0
HFD1_k127_6263125_3 PAS fold - - - 0.00000000000000000000001523 103.0
HFD1_k127_6263867_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1339.0
HFD1_k127_6263867_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.488e-284 876.0
HFD1_k127_6263867_10 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000009891 166.0
HFD1_k127_6263867_11 GGDEF domain - - - 0.000000000000000000000000000000000000000004775 163.0
HFD1_k127_6263867_12 Multicopper oxidase - - - 0.00000000000000000000000000008282 121.0
HFD1_k127_6263867_13 copper-resistance protein, CopA family - - - 0.00000000000000000000001106 107.0
HFD1_k127_6263867_14 Thioesterase superfamily - - - 0.0000000000000000001673 88.0
HFD1_k127_6263867_15 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000385 76.0
HFD1_k127_6263867_16 - - - - 0.000000009691 56.0
HFD1_k127_6263867_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 8.953e-254 785.0
HFD1_k127_6263867_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 587.0
HFD1_k127_6263867_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 567.0
HFD1_k127_6263867_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 377.0
HFD1_k127_6263867_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001566 272.0
HFD1_k127_6263867_7 Ribosomal protein S9/S16 K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000183 265.0
HFD1_k127_6263867_8 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000000000000000004171 218.0
HFD1_k127_6263867_9 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000001446 181.0
HFD1_k127_626935_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity - - - 5.111e-206 648.0
HFD1_k127_626935_1 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 433.0
HFD1_k127_626935_2 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001714 268.0
HFD1_k127_626935_3 - - - - 0.000000000000000000000000000000000000000000000000000001219 197.0
HFD1_k127_626935_4 - - - - 0.0000000000000000000000000000000000000518 147.0
HFD1_k127_626935_5 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000005004 92.0
HFD1_k127_6287581_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 2057.0
HFD1_k127_6287581_1 Elongator protein 3 MiaB NifB - - - 1.117e-302 938.0
HFD1_k127_6287581_10 - - - - 0.0000000000000000006789 88.0
HFD1_k127_6287581_11 - - - - 0.00000000000000002335 83.0
HFD1_k127_6287581_12 signal peptide - - - 0.00000000000005642 75.0
HFD1_k127_6287581_13 - - - - 0.00000000005234 69.0
HFD1_k127_6287581_14 - - - - 0.000000001683 61.0
HFD1_k127_6287581_15 - - - - 0.0000003215 55.0
HFD1_k127_6287581_16 - - - - 0.00001168 51.0
HFD1_k127_6287581_2 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 572.0
HFD1_k127_6287581_3 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 362.0
HFD1_k127_6287581_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 306.0
HFD1_k127_6287581_5 Haemolysin-III related K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000001532 251.0
HFD1_k127_6287581_6 - - - - 0.000000000000000000000000000000000044 136.0
HFD1_k127_6287581_7 Ribonuclease B OB domain K03704 - - 0.0000000000000000000000000000003234 126.0
HFD1_k127_6287581_8 Cold shock protein domain K03704 - - 0.000000000000000000000000007012 113.0
HFD1_k127_6287581_9 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000003069 110.0
HFD1_k127_6289356_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1301.0
HFD1_k127_6289356_1 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.0 1015.0
HFD1_k127_6289356_10 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 481.0
HFD1_k127_6289356_11 HlyD family secretion protein K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 456.0
HFD1_k127_6289356_12 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 443.0
HFD1_k127_6289356_13 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 437.0
HFD1_k127_6289356_14 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 425.0
HFD1_k127_6289356_15 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 407.0
HFD1_k127_6289356_16 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 357.0
HFD1_k127_6289356_17 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 362.0
HFD1_k127_6289356_18 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 333.0
HFD1_k127_6289356_19 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 325.0
HFD1_k127_6289356_2 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.114e-305 942.0
HFD1_k127_6289356_20 DedA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 309.0
HFD1_k127_6289356_21 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000148 280.0
HFD1_k127_6289356_22 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000001173 246.0
HFD1_k127_6289356_23 Disulfide bond formation protein DsbB K03611 - - 0.0000000000000000000000000000000000000000000000000001047 191.0
HFD1_k127_6289356_24 carbonate dehydratase activity K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000003197 185.0
HFD1_k127_6289356_25 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000001996 181.0
HFD1_k127_6289356_26 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000003089 177.0
HFD1_k127_6289356_27 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000000000000003379 182.0
HFD1_k127_6289356_28 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000002266 156.0
HFD1_k127_6289356_29 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000006841 153.0
HFD1_k127_6289356_3 ATPases associated with a variety of cellular activities K02003,K05685 - - 5.452e-286 895.0
HFD1_k127_6289356_30 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000008502 97.0
HFD1_k127_6289356_31 oligosaccharyl transferase activity - - - 0.0000000000000000003194 89.0
HFD1_k127_6289356_32 - - - - 0.0000000000000000003679 96.0
HFD1_k127_6289356_33 oligosaccharyl transferase activity - - - 0.00000000000000004905 82.0
HFD1_k127_6289356_34 Bacterial protein of unknown function (DUF924) - - - 0.0000000006841 62.0
HFD1_k127_6289356_4 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 6.334e-268 834.0
HFD1_k127_6289356_5 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.858e-261 816.0
HFD1_k127_6289356_6 Alcohol dehydrogenase GroES-like domain K00001,K14446 - 1.1.1.1,1.3.1.85 2.29e-250 777.0
HFD1_k127_6289356_7 homoserine dehydrogenase K00003 - 1.1.1.3 3.321e-223 700.0
HFD1_k127_6289356_8 Belongs to the thiolase family K00626 - 2.3.1.9 5.329e-205 643.0
HFD1_k127_6289356_9 FAD binding domain K20940 - 1.14.13.218 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 593.0
HFD1_k127_6456582_0 Biotin carboxylase C-terminal domain K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 0.0 1012.0
HFD1_k127_6456582_1 Carboxyl transferase domain K01966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 3.835e-298 920.0
HFD1_k127_6456582_10 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000426 194.0
HFD1_k127_6456582_11 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000004296 163.0
HFD1_k127_6456582_12 Domain of unknown function (DUF4260) - - - 0.000000000000000000000000000000000000527 143.0
HFD1_k127_6456582_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000003388 152.0
HFD1_k127_6456582_14 PFAM AIG2 family protein - - - 0.0000000000000000000000000000001482 129.0
HFD1_k127_6456582_15 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000001943 124.0
HFD1_k127_6456582_16 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000009283 93.0
HFD1_k127_6456582_17 cheY-homologous receiver domain - - - 0.00000000000000000008078 97.0
HFD1_k127_6456582_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 6.369e-250 775.0
HFD1_k127_6456582_3 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 407.0
HFD1_k127_6456582_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 354.0
HFD1_k127_6456582_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 351.0
HFD1_k127_6456582_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 340.0
HFD1_k127_6456582_7 ATP12 chaperone protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 287.0
HFD1_k127_6456582_8 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001545 243.0
HFD1_k127_6456582_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000006716 212.0
HFD1_k127_6472196_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1118.0
HFD1_k127_6472196_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 372.0
HFD1_k127_6472196_10 membrane - - - 0.000000003413 61.0
HFD1_k127_6472196_11 - - - - 0.00000000421 60.0
HFD1_k127_6472196_2 Transcriptional regulatory protein, C terminal - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 366.0
HFD1_k127_6472196_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 331.0
HFD1_k127_6472196_4 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 319.0
HFD1_k127_6472196_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000068 217.0
HFD1_k127_6472196_6 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000001108 198.0
HFD1_k127_6472196_7 ABC transporter K06147,K11004 - - 0.0000000000000000000000000000000000000000005382 160.0
HFD1_k127_6472196_8 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000000000000000974 146.0
HFD1_k127_6472196_9 Protein of unknown function (DUF3606) - - - 0.000000000004367 69.0
HFD1_k127_6478767_0 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 460.0
HFD1_k127_6478767_1 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
HFD1_k127_6478767_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002213 281.0
HFD1_k127_6478767_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005755 263.0
HFD1_k127_6478767_4 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000005293 178.0
HFD1_k127_6496347_0 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 342.0
HFD1_k127_6496347_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 314.0
HFD1_k127_6508391_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 575.0
HFD1_k127_6508391_1 transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 398.0
HFD1_k127_6508391_2 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 280.0
HFD1_k127_6508391_3 Peptidase propeptide and YPEB domain - - - 0.00000000000000000000000000000001965 128.0
HFD1_k127_6508391_4 Peptidase propeptide and YPEB domain - - - 0.0000000000000000000006325 100.0
HFD1_k127_6508391_5 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000008467 94.0
HFD1_k127_6560385_0 Cytochrome c554 and c-prime - - - 1.297e-280 876.0
HFD1_k127_6560385_1 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 302.0
HFD1_k127_6574461_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.831e-265 821.0
HFD1_k127_6574461_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 5.77e-242 758.0
HFD1_k127_6574461_10 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000007591 262.0
HFD1_k127_6574461_11 Bacterial transcription activator, effector binding domain - - - 0.000000000000000000000000000000000000000000000000000000000005024 218.0
HFD1_k127_6574461_12 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000001395 211.0
HFD1_k127_6574461_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002497 203.0
HFD1_k127_6574461_14 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000005222 207.0
HFD1_k127_6574461_15 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000001553 207.0
HFD1_k127_6574461_16 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001938 179.0
HFD1_k127_6574461_17 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000004335 172.0
HFD1_k127_6574461_18 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000007274 168.0
HFD1_k127_6574461_19 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.00000000000000000000000000000000001 139.0
HFD1_k127_6574461_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 5.291e-195 612.0
HFD1_k127_6574461_20 - - - - 0.00000000000000000000001525 102.0
HFD1_k127_6574461_21 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000001799 103.0
HFD1_k127_6574461_22 Isochorismatase family - - - 0.000000000000000000005206 99.0
HFD1_k127_6574461_23 - - - - 0.00000000000000000001299 99.0
HFD1_k127_6574461_24 - - - - 0.00000002828 60.0
HFD1_k127_6574461_3 MiaB-like tRNA modifying enzyme K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 547.0
HFD1_k127_6574461_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 457.0
HFD1_k127_6574461_5 HpcH/HpaI aldolase/citrate lyase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 418.0
HFD1_k127_6574461_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 375.0
HFD1_k127_6574461_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 330.0
HFD1_k127_6574461_8 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 324.0
HFD1_k127_6574461_9 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001029 267.0
HFD1_k127_6645466_0 GTP-binding protein TypA K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0 1037.0
HFD1_k127_6645466_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1037.0
HFD1_k127_6645466_10 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 448.0
HFD1_k127_6645466_11 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 432.0
HFD1_k127_6645466_12 PFAM regulatory protein LysR K11921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 421.0
HFD1_k127_6645466_13 Oxidoreductase molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 406.0
HFD1_k127_6645466_14 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 307.0
HFD1_k127_6645466_15 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 299.0
HFD1_k127_6645466_16 PAP2 superfamily K12978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002436 270.0
HFD1_k127_6645466_17 invasion associated locus B - - - 0.000000000000000000000000000000000000000000000000000000000008857 211.0
HFD1_k127_6645466_18 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000000000000000000000001412 211.0
HFD1_k127_6645466_19 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000001842 188.0
HFD1_k127_6645466_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.893e-236 734.0
HFD1_k127_6645466_20 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000003315 176.0
HFD1_k127_6645466_21 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000001944 157.0
HFD1_k127_6645466_22 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000003881 145.0
HFD1_k127_6645466_23 succinate dehydrogenase K00242 - - 0.0000000000000000000000000000000000003902 145.0
HFD1_k127_6645466_24 YGGT family K02221 - - 0.00000000000000000000000000000000009088 135.0
HFD1_k127_6645466_25 Peptidase M48 - - - 0.0000000000000000000000000000002084 132.0
HFD1_k127_6645466_26 DUF167 K09131 - - 0.00000000000000000000000000006681 118.0
HFD1_k127_6645466_27 - - - - 0.0000000000000000000005841 100.0
HFD1_k127_6645466_28 - - - - 0.000000000000000000001219 100.0
HFD1_k127_6645466_29 - - - - 0.000000000000000000001623 99.0
HFD1_k127_6645466_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 8.062e-206 646.0
HFD1_k127_6645466_30 Cytochrome c - - - 0.0000000000000000001294 91.0
HFD1_k127_6645466_31 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000001078 85.0
HFD1_k127_6645466_32 TIGRFAM pentapeptide MXKDX repeat protein - - - 0.0000000000001616 72.0
HFD1_k127_6645466_34 Glutathione-dependent formaldehyde-activating - - - 0.0005016 42.0
HFD1_k127_6645466_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 605.0
HFD1_k127_6645466_5 dehydratase K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 542.0
HFD1_k127_6645466_6 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 494.0
HFD1_k127_6645466_7 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 482.0
HFD1_k127_6645466_8 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 472.0
HFD1_k127_6645466_9 Carbon-nitrogen hydrolase K01501,K01502 - 3.5.5.1,3.5.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 455.0
HFD1_k127_6659698_0 DHH family K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 2.742e-276 860.0
HFD1_k127_6659698_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446,K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 533.0
HFD1_k127_6659698_2 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
HFD1_k127_6659698_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000002903 133.0
HFD1_k127_6765141_0 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 526.0
HFD1_k127_6765141_1 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 447.0
HFD1_k127_6765141_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 397.0
HFD1_k127_6765141_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 409.0
HFD1_k127_6765141_4 5'-3' exonuclease K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 302.0
HFD1_k127_6765141_5 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000005479 70.0
HFD1_k127_6765141_6 ABC transporter substrate binding protein K01989 - - 0.00000342 54.0
HFD1_k127_6765141_7 Protein of unknown function (DUF3489) - - - 0.0005558 48.0
HFD1_k127_6825121_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 300.0
HFD1_k127_6825121_1 - - - - 0.0000000000000000000000000000002377 127.0
HFD1_k127_6825121_2 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000003336 123.0
HFD1_k127_6899498_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 539.0
HFD1_k127_6899498_1 Domain of unknown function (DUF4118) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 367.0
HFD1_k127_6899498_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009797 279.0
HFD1_k127_6899498_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000007357 205.0
HFD1_k127_6899498_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000000000001538 168.0
HFD1_k127_6899498_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000005554 108.0
HFD1_k127_6929586_0 Transglycosylase SLT domain K00786,K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 531.0
HFD1_k127_6929586_1 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 522.0
HFD1_k127_6929586_2 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 397.0
HFD1_k127_6929586_3 Cupin - - - 0.000000000000002283 78.0
HFD1_k127_6929586_4 ATP dependent DNA ligase C terminal region - - - 0.0000000001189 66.0
HFD1_k127_6934963_0 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 342.0
HFD1_k127_6934963_1 NADH ubiquinone oxidoreductase subunit NDUFA12 K00356 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000009499 251.0
HFD1_k127_6934963_2 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002389 258.0
HFD1_k127_6934963_3 'PFAM Response regulator receiver - - - 0.00000000279 61.0
HFD1_k127_6975189_0 L,D-transpeptidase catalytic domain - - - 3.24e-231 726.0
HFD1_k127_6975189_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001679 278.0
HFD1_k127_7011058_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1392.0
HFD1_k127_7011058_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 0.0 1272.0
HFD1_k127_7011058_10 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 492.0
HFD1_k127_7011058_11 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 491.0
HFD1_k127_7011058_12 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 432.0
HFD1_k127_7011058_13 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 419.0
HFD1_k127_7011058_14 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 417.0
HFD1_k127_7011058_15 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 390.0
HFD1_k127_7011058_16 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 340.0
HFD1_k127_7011058_17 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 334.0
HFD1_k127_7011058_18 Pyrogallol hydroxytransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 328.0
HFD1_k127_7011058_19 PFAM peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 327.0
HFD1_k127_7011058_2 benzoate-CoA ligase K04105 - 6.2.1.25,6.2.1.27 4.07e-258 803.0
HFD1_k127_7011058_20 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 330.0
HFD1_k127_7011058_21 KR domain K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 311.0
HFD1_k127_7011058_22 KR domain K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001358 288.0
HFD1_k127_7011058_23 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K04107 - 1.2.5.3,1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005251 268.0
HFD1_k127_7011058_24 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002046 271.0
HFD1_k127_7011058_25 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004531 261.0
HFD1_k127_7011058_27 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000007542 192.0
HFD1_k127_7011058_28 DMSO reductase anchor subunit (DmsC) K18363 - - 0.00000000000000000000000000000000000000000000000001388 199.0
HFD1_k127_7011058_29 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000003118 184.0
HFD1_k127_7011058_3 benzoyl-CoA reductase K04113 - 1.3.7.8 2.445e-245 769.0
HFD1_k127_7011058_30 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000001303 173.0
HFD1_k127_7011058_31 COG0826 Collagenase and related proteases K08303 - - 0.000000000000000000000000000000000000000000266 167.0
HFD1_k127_7011058_32 ferredoxin - - - 0.0000000000000000000000000000000000001213 142.0
HFD1_k127_7011058_33 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000001549 146.0
HFD1_k127_7011058_34 transcriptional regulator - - - 0.000000000000000000000000000000000008 141.0
HFD1_k127_7011058_35 Rubrerythrin - - - 0.00000000000000000000000000000007938 132.0
HFD1_k127_7011058_36 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000002895 128.0
HFD1_k127_7011058_38 lipid carrier protein - - - 0.000000000000000000000000001536 120.0
HFD1_k127_7011058_39 DoxX K15977 - - 0.0000000000000000006593 92.0
HFD1_k127_7011058_4 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 4.13e-226 707.0
HFD1_k127_7011058_40 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.000000000008746 65.0
HFD1_k127_7011058_41 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.000000002875 59.0
HFD1_k127_7011058_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 8.149e-224 704.0
HFD1_k127_7011058_6 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 1.584e-208 663.0
HFD1_k127_7011058_7 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 595.0
HFD1_k127_7011058_8 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 592.0
HFD1_k127_7011058_9 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 548.0
HFD1_k127_7195920_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.357e-294 913.0
HFD1_k127_7195920_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 6.059e-205 642.0
HFD1_k127_7195920_2 Bacterial extracellular solute-binding protein, family 7 - - - 4.73e-198 621.0
HFD1_k127_7195920_3 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 443.0
HFD1_k127_7195920_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 381.0
HFD1_k127_7195920_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000001045 202.0
HFD1_k127_7195920_6 ABC transporter K02471 - - 0.00000000000000000000000000000000000000003851 154.0
HFD1_k127_7195920_7 META domain - - - 0.000000000000000001085 91.0
HFD1_k127_7195920_8 META domain - - - 0.00004913 47.0
HFD1_k127_7243499_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000344 286.0
HFD1_k127_7243499_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000001472 181.0
HFD1_k127_7365728_0 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 495.0
HFD1_k127_7365728_1 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 493.0
HFD1_k127_7365728_10 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K10003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 331.0
HFD1_k127_7365728_11 Binding-protein-dependent transport system inner membrane component K02029,K10002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 335.0
HFD1_k127_7365728_12 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 331.0
HFD1_k127_7365728_13 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
HFD1_k127_7365728_14 Molybdopterin guanine dinucleotide synthesis protein B K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000002445 231.0
HFD1_k127_7365728_15 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.0000007176 53.0
HFD1_k127_7365728_2 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 461.0
HFD1_k127_7365728_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 464.0
HFD1_k127_7365728_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 424.0
HFD1_k127_7365728_5 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 412.0
HFD1_k127_7365728_6 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 406.0
HFD1_k127_7365728_7 ABC transporter K10004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 389.0
HFD1_k127_7365728_8 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 392.0
HFD1_k127_7365728_9 ABC-type tungstate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 344.0
HFD1_k127_7485550_0 Thi4 family K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 5.341e-295 911.0
HFD1_k127_7485550_1 Tetratricopeptide repeat - - - 1.177e-244 767.0
HFD1_k127_7485550_10 FES K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 479.0
HFD1_k127_7485550_11 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 404.0
HFD1_k127_7485550_12 Peptidase family S49 K04773,K04774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 371.0
HFD1_k127_7485550_13 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 353.0
HFD1_k127_7485550_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 344.0
HFD1_k127_7485550_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 317.0
HFD1_k127_7485550_16 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 304.0
HFD1_k127_7485550_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 294.0
HFD1_k127_7485550_18 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007298 244.0
HFD1_k127_7485550_19 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000000001201 240.0
HFD1_k127_7485550_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.056e-209 661.0
HFD1_k127_7485550_20 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
HFD1_k127_7485550_21 COG1651 protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000006802 231.0
HFD1_k127_7485550_22 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000000000000000004331 216.0
HFD1_k127_7485550_23 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000000000000000000007285 196.0
HFD1_k127_7485550_24 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000001771 180.0
HFD1_k127_7485550_25 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000007108 150.0
HFD1_k127_7485550_26 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.0000000000000000000000000000000000001249 147.0
HFD1_k127_7485550_27 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000005267 138.0
HFD1_k127_7485550_28 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000000004619 111.0
HFD1_k127_7485550_29 - - - - 0.00000000000000000001153 100.0
HFD1_k127_7485550_3 PFAM Xanthine uracil vitamin C permease K06901 - - 4.813e-205 646.0
HFD1_k127_7485550_30 Predicted membrane protein (DUF2207) - - - 0.00000000000000000003256 97.0
HFD1_k127_7485550_31 Tautomerase enzyme - - - 0.00000000000009588 72.0
HFD1_k127_7485550_32 Predicted membrane protein (DUF2207) - - - 0.000000000003517 69.0
HFD1_k127_7485550_33 - - - - 0.000000000009057 67.0
HFD1_k127_7485550_4 Elongator protein 3, MiaB family, Radical SAM - - - 1.582e-195 615.0
HFD1_k127_7485550_5 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 604.0
HFD1_k127_7485550_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 583.0
HFD1_k127_7485550_7 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 537.0
HFD1_k127_7485550_8 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 491.0
HFD1_k127_7485550_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 496.0
HFD1_k127_7578195_0 5-aminolevulinic acid synthase K00643 - 2.3.1.37 1.807e-229 716.0
HFD1_k127_7578195_1 NUDIX domain - - - 0.0000000000000000000000000000000002736 136.0
HFD1_k127_7578195_2 Ammonia monooxygenase K07120 - - 0.0000003116 53.0
HFD1_k127_7651047_0 Transposase K07487 - - 7.105e-216 679.0
HFD1_k127_7713383_0 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002139 252.0
HFD1_k127_7713383_1 Membrane-associated sensor, integral membrane domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002178 258.0
HFD1_k127_7713383_2 - - - - 0.00000000000000000000000000000000000000000000001999 173.0
HFD1_k127_7713383_3 DoxX K15977 - - 0.0000000000000000000000000000000000000000002937 162.0
HFD1_k127_7713383_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000007183 158.0
HFD1_k127_7713383_5 PilZ domain - - - 0.00000000000000000000003181 104.0
HFD1_k127_7713383_6 - - - - 0.0000000000000000000001334 100.0
HFD1_k127_7713383_7 - - - - 0.00000000000000002551 87.0
HFD1_k127_7713383_8 - - - - 0.00008558 47.0
HFD1_k127_7718895_0 ABC transporter K06147,K11085 - - 4.966e-262 819.0
HFD1_k127_7718895_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 384.0
HFD1_k127_7718895_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 368.0
HFD1_k127_7718895_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 353.0
HFD1_k127_7718895_4 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 347.0
HFD1_k127_7718895_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 348.0
HFD1_k127_7718895_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 340.0
HFD1_k127_7727106_0 Enoyl-CoA hydratase/isomerase K00020,K01692 - 1.1.1.31,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 338.0
HFD1_k127_7784814_0 - - - - 0.00000000000000000000000003108 118.0
HFD1_k127_7784814_1 - - - - 0.000000000000000000000003386 107.0
HFD1_k127_7784814_2 - - - - 0.00000000000000000001391 94.0
HFD1_k127_7784814_3 - - - - 0.0000001206 56.0
HFD1_k127_7813214_0 Alpha/beta hydrolase family K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 545.0
HFD1_k127_7813214_1 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 331.0
HFD1_k127_7813214_2 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004786 282.0
HFD1_k127_7813214_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000001836 219.0
HFD1_k127_7813214_4 transferase activity, transferring glycosyl groups - - - 0.0000001962 52.0
HFD1_k127_7813214_5 alpha/beta hydrolase fold - - - 0.0004084 48.0
HFD1_k127_7871890_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1749.0
HFD1_k127_7871890_1 Glucose / Sorbosone dehydrogenase - - - 1.612e-205 648.0
HFD1_k127_7871890_10 Cytochrome c K17230 - - 0.00000000000000000000000000000000000000000000000000000000000000000001679 239.0
HFD1_k127_7871890_11 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001482 217.0
HFD1_k127_7871890_12 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000000000000000000009565 130.0
HFD1_k127_7871890_13 Protein of unknown function (DUF1236) - - - 0.000000000000000000000008768 104.0
HFD1_k127_7871890_14 coenzyme PQQ synthesis K06138 - - 0.00000000000000000000004446 102.0
HFD1_k127_7871890_15 - - - - 0.000006308 52.0
HFD1_k127_7871890_16 Protein conserved in bacteria - - - 0.000007015 52.0
HFD1_k127_7871890_18 domain, Protein - - - 0.0004328 50.0
HFD1_k127_7871890_2 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 579.0
HFD1_k127_7871890_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 522.0
HFD1_k127_7871890_4 Iron-sulfur cluster-binding domain K06139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 506.0
HFD1_k127_7871890_5 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 500.0
HFD1_k127_7871890_6 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137,K06138 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 387.0
HFD1_k127_7871890_7 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 345.0
HFD1_k127_7871890_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001402 271.0
HFD1_k127_7871890_9 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001147 256.0
HFD1_k127_7896720_0 COG3666 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 576.0
HFD1_k127_7896720_1 Protein of unknown function (DUF938) - - - 0.00000000000000003206 83.0
HFD1_k127_7898814_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.818e-295 910.0
HFD1_k127_7898814_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 536.0
HFD1_k127_7898814_2 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 291.0
HFD1_k127_7944460_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 461.0
HFD1_k127_7944460_1 NMT1/THI5 like K02051 - - 0.0000001827 59.0
HFD1_k127_7944460_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00006179 45.0
HFD1_k127_7963628_0 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 586.0
HFD1_k127_7963628_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 421.0
HFD1_k127_7963628_2 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 338.0
HFD1_k127_7963628_3 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 286.0
HFD1_k127_7963628_4 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002104 284.0
HFD1_k127_7963628_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006736 259.0
HFD1_k127_7963628_6 Single cache domain 3 K03406 - - 0.000000000000000000000000000000000000000000000000166 182.0
HFD1_k127_7963628_7 Ureidoglycolate lyase - - - 0.000000000000000000000000000000000000000005851 159.0
HFD1_k127_7963628_8 Putative diguanylate phosphodiesterase - - - 0.000000000000000005241 95.0
HFD1_k127_7963628_9 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000001888 71.0
HFD1_k127_815404_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 314.0
HFD1_k127_815404_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 310.0
HFD1_k127_815404_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002586 262.0
HFD1_k127_815404_3 Glutathione S-transferase, N-terminal domain K01800 - 5.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001797 250.0
HFD1_k127_815404_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000005993 240.0
HFD1_k127_815404_5 Haem-degrading - - - 0.000000000000000000000000000000000000000000000005156 183.0
HFD1_k127_815404_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000001408 139.0
HFD1_k127_815404_7 Metallopeptidase family M24 - - - 0.000000000000000000000006651 108.0
HFD1_k127_826100_0 Adenylate cyclase - - - 3.208e-249 778.0
HFD1_k127_826100_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 2.472e-220 687.0
HFD1_k127_826100_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0009165 42.0
HFD1_k127_826100_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 419.0
HFD1_k127_826100_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 370.0
HFD1_k127_826100_4 ABC-type transport auxiliary lipoprotein component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 325.0
HFD1_k127_826100_5 - - - - 0.00000000000000000000000000000002787 130.0
HFD1_k127_826100_6 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000006376 115.0
HFD1_k127_826100_7 Eukaryotic cytochrome b561 - - - 0.00000000000000000000000000449 120.0
HFD1_k127_826100_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000009834 86.0
HFD1_k127_826100_9 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.000000000000004493 79.0
HFD1_k127_853824_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1170.0
HFD1_k127_853824_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1120.0
HFD1_k127_853824_10 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.781e-233 730.0
HFD1_k127_853824_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 3.799e-228 717.0
HFD1_k127_853824_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 2.152e-224 700.0
HFD1_k127_853824_13 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.104e-216 687.0
HFD1_k127_853824_14 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 4.777e-210 664.0
HFD1_k127_853824_15 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.697e-204 644.0
HFD1_k127_853824_16 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 1.838e-197 622.0
HFD1_k127_853824_17 Major Facilitator Superfamily - - - 2.574e-196 622.0
HFD1_k127_853824_18 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 598.0
HFD1_k127_853824_19 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 550.0
HFD1_k127_853824_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1065.0
HFD1_k127_853824_20 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 536.0
HFD1_k127_853824_21 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 510.0
HFD1_k127_853824_22 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 472.0
HFD1_k127_853824_23 Permease K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 464.0
HFD1_k127_853824_24 Acyl transferase domain K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 449.0
HFD1_k127_853824_25 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 443.0
HFD1_k127_853824_26 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 439.0
HFD1_k127_853824_27 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 425.0
HFD1_k127_853824_28 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 427.0
HFD1_k127_853824_29 Permease K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 422.0
HFD1_k127_853824_3 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1037.0
HFD1_k127_853824_30 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 410.0
HFD1_k127_853824_31 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 407.0
HFD1_k127_853824_32 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 398.0
HFD1_k127_853824_33 Domain of unknown function (DUF1732) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 390.0
HFD1_k127_853824_34 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 369.0
HFD1_k127_853824_35 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 370.0
HFD1_k127_853824_36 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 315.0
HFD1_k127_853824_37 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 308.0
HFD1_k127_853824_38 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 299.0
HFD1_k127_853824_39 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 295.0
HFD1_k127_853824_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.191e-316 990.0
HFD1_k127_853824_40 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 293.0
HFD1_k127_853824_41 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001582 284.0
HFD1_k127_853824_42 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002159 275.0
HFD1_k127_853824_43 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004159 269.0
HFD1_k127_853824_44 Bacterial dnaA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002409 271.0
HFD1_k127_853824_45 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
HFD1_k127_853824_46 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001285 261.0
HFD1_k127_853824_47 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000004432 264.0
HFD1_k127_853824_48 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000002834 243.0
HFD1_k127_853824_49 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000288 247.0
HFD1_k127_853824_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 7.015e-286 885.0
HFD1_k127_853824_50 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000008315 237.0
HFD1_k127_853824_51 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000001057 231.0
HFD1_k127_853824_52 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000004587 222.0
HFD1_k127_853824_53 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
HFD1_k127_853824_54 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000002962 211.0
HFD1_k127_853824_55 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.0000000000000000000000000000000000000000000000000001958 188.0
HFD1_k127_853824_56 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000009522 185.0
HFD1_k127_853824_57 Outer membrane protein beta-barrel domain K16079 - - 0.00000000000000000000000000000000000000000006348 170.0
HFD1_k127_853824_58 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000001236 151.0
HFD1_k127_853824_59 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001308 147.0
HFD1_k127_853824_6 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.629e-269 842.0
HFD1_k127_853824_60 MAPEG family - - - 0.0000000000000000000000000000000003592 136.0
HFD1_k127_853824_61 methylamine metabolic process K03885,K15977 - 1.6.99.3 0.0000000000000000000000000002584 119.0
HFD1_k127_853824_62 - - - - 0.000000000000000000009176 102.0
HFD1_k127_853824_63 - - - - 0.000000000000000000462 94.0
HFD1_k127_853824_64 - - - - 0.000000000000000006385 90.0
HFD1_k127_853824_65 DoxX K15977 - - 0.00000000000004871 78.0
HFD1_k127_853824_66 Leucyl/phenylalanyl-tRNA protein transferase K00684 - 2.3.2.6 0.000000000004872 75.0
HFD1_k127_853824_67 amidohydrolase - - - 0.00000119 60.0
HFD1_k127_853824_68 Amidohydrolase - - - 0.00009277 45.0
HFD1_k127_853824_7 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 2.622e-268 832.0
HFD1_k127_853824_8 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 1.621e-248 781.0
HFD1_k127_853824_9 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 4.779e-242 755.0
HFD1_k127_884274_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1420.0
HFD1_k127_884274_1 FtsX-like permease family K02004 - - 0.0 1059.0
HFD1_k127_884274_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006311 270.0
HFD1_k127_884274_11 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002434 272.0
HFD1_k127_884274_12 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000435 264.0
HFD1_k127_884274_13 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000005516 248.0
HFD1_k127_884274_14 Intracellular septation protein A K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007469 241.0
HFD1_k127_884274_15 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000000000001211 231.0
HFD1_k127_884274_16 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000005553 209.0
HFD1_k127_884274_17 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000007405 194.0
HFD1_k127_884274_18 - - - - 0.000000000000000000000000000000000000000000000002629 177.0
HFD1_k127_884274_19 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000000000000000000000002307 173.0
HFD1_k127_884274_2 AFG1-like ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 513.0
HFD1_k127_884274_20 - - - - 0.00000000000001176 79.0
HFD1_k127_884274_21 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000000000409 65.0
HFD1_k127_884274_22 - - - - 0.0000478 49.0
HFD1_k127_884274_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 456.0
HFD1_k127_884274_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 381.0
HFD1_k127_884274_5 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 364.0
HFD1_k127_884274_6 Inhibitor of apoptosis-promoting Bax1 K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 351.0
HFD1_k127_884274_7 ABC transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 343.0
HFD1_k127_884274_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 319.0
HFD1_k127_884274_9 Redoxin K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005484 275.0
HFD1_k127_897850_0 Glutamate synthase K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.0 2546.0
HFD1_k127_897850_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1705.0
HFD1_k127_897850_10 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 2.483e-206 646.0
HFD1_k127_897850_11 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 595.0
HFD1_k127_897850_12 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 597.0
HFD1_k127_897850_13 Transglycosylase SLT domain K00786,K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 577.0
HFD1_k127_897850_14 cobalamin synthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 567.0
HFD1_k127_897850_15 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 562.0
HFD1_k127_897850_16 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 539.0
HFD1_k127_897850_17 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 512.0
HFD1_k127_897850_18 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 480.0
HFD1_k127_897850_19 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 463.0
HFD1_k127_897850_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0 1052.0
HFD1_k127_897850_20 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 462.0
HFD1_k127_897850_21 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 454.0
HFD1_k127_897850_22 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 465.0
HFD1_k127_897850_23 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 451.0
HFD1_k127_897850_24 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 448.0
HFD1_k127_897850_25 PFAM ABC transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 446.0
HFD1_k127_897850_26 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 441.0
HFD1_k127_897850_27 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 422.0
HFD1_k127_897850_28 Anaphase-promoting complex subunit 4 WD40 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 413.0
HFD1_k127_897850_29 Inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 377.0
HFD1_k127_897850_3 COG0339 Zn-dependent oligopeptidases K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 1.329e-303 951.0
HFD1_k127_897850_30 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 372.0
HFD1_k127_897850_31 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 376.0
HFD1_k127_897850_32 Protein of unknown function (DUF459) K09795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 384.0
HFD1_k127_897850_33 AAA domain, putative AbiEii toxin, Type IV TA system K02074,K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 361.0
HFD1_k127_897850_34 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 349.0
HFD1_k127_897850_35 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 349.0
HFD1_k127_897850_36 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 325.0
HFD1_k127_897850_37 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 292.0
HFD1_k127_897850_38 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 296.0
HFD1_k127_897850_39 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 289.0
HFD1_k127_897850_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.768e-298 931.0
HFD1_k127_897850_40 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009591 261.0
HFD1_k127_897850_41 Protein of unknown function (DUF1007) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007304 240.0
HFD1_k127_897850_42 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004084 240.0
HFD1_k127_897850_43 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000000000000000000000000001268 224.0
HFD1_k127_897850_44 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000001128 218.0
HFD1_k127_897850_45 Response regulator receiver K13589 - - 0.00000000000000000000000000000000000000000000000000000000000008257 214.0
HFD1_k127_897850_46 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000002637 191.0
HFD1_k127_897850_47 Predicted permease - - - 0.00000000000000000000000000000000000000000000000006193 182.0
HFD1_k127_897850_48 Predicted permease - - - 0.0000000000000000000000000000000000000000000005301 171.0
HFD1_k127_897850_49 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000002179 159.0
HFD1_k127_897850_5 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 2.166e-268 830.0
HFD1_k127_897850_50 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000002344 142.0
HFD1_k127_897850_51 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000006068 129.0
HFD1_k127_897850_52 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000001188 122.0
HFD1_k127_897850_53 - - - - 0.000000000000000000000004433 103.0
HFD1_k127_897850_54 L,D-transpeptidase catalytic domain - - - 0.0000000000000000004082 88.0
HFD1_k127_897850_55 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000149 79.0
HFD1_k127_897850_57 Protein conserved in bacteria - - - 0.00000000000001927 82.0
HFD1_k127_897850_58 cell septum assembly - - - 0.0000000000002038 76.0
HFD1_k127_897850_59 Domain of unknown function (DUF5067) - - - 0.000004044 55.0
HFD1_k127_897850_6 NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.511e-253 787.0
HFD1_k127_897850_60 Protein conserved in bacteria - - - 0.000004552 54.0
HFD1_k127_897850_62 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0003476 48.0
HFD1_k127_897850_63 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0005064 46.0
HFD1_k127_897850_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.764e-245 771.0
HFD1_k127_897850_8 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.063e-244 763.0
HFD1_k127_897850_9 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.814e-209 660.0
HFD1_k127_899096_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0 1091.0
HFD1_k127_899096_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 0.0 1052.0
HFD1_k127_899096_10 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 393.0
HFD1_k127_899096_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 375.0
HFD1_k127_899096_12 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 312.0
HFD1_k127_899096_13 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001025 273.0
HFD1_k127_899096_14 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003274 257.0
HFD1_k127_899096_15 surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000004448 226.0
HFD1_k127_899096_16 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000000003283 216.0
HFD1_k127_899096_17 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000006495 208.0
HFD1_k127_899096_18 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000000002798 196.0
HFD1_k127_899096_19 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000009022 190.0
HFD1_k127_899096_2 Cytochrome c-type biogenesis protein K02198 - - 5.799e-315 975.0
HFD1_k127_899096_20 Cytochrome C biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000009825 181.0
HFD1_k127_899096_21 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000002201 189.0
HFD1_k127_899096_22 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000001607 169.0
HFD1_k127_899096_23 Protein of unknown function (DUF3168) - - - 0.000000000000000000000000000000000000000006413 158.0
HFD1_k127_899096_24 Ribbon-helix-helix domain - - - 0.0000000000000000000006194 97.0
HFD1_k127_899096_25 Predicted membrane protein (DUF2231) - - - 0.000000000000000002198 85.0
HFD1_k127_899096_26 COG5281, Phage-related minor tail protein - - - 0.000000000000000003103 85.0
HFD1_k127_899096_27 Predicted membrane protein (DUF2231) - - - 0.0000000000002423 76.0
HFD1_k127_899096_29 PFAM Patatin K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000008694 59.0
HFD1_k127_899096_3 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 8.463e-299 934.0
HFD1_k127_899096_30 Flp Fap pilin component K02651 - - 0.0000001106 56.0
HFD1_k127_899096_31 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000007089 57.0
HFD1_k127_899096_33 - - - - 0.0001057 49.0
HFD1_k127_899096_4 COG2873 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 4.86e-229 715.0
HFD1_k127_899096_5 Histidine kinase - - - 8.865e-200 631.0
HFD1_k127_899096_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 4.761e-198 627.0
HFD1_k127_899096_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 612.0
HFD1_k127_899096_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 456.0
HFD1_k127_899096_9 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 422.0
HFD1_k127_931553_0 Transglycosylase SLT domain K08309 - - 2.983e-242 767.0
HFD1_k127_931553_1 MotA TolQ ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 426.0
HFD1_k127_931553_2 OmpA family K02557 - - 0.000000000000003989 75.0
HFD1_k127_944673_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.397e-309 956.0
HFD1_k127_944673_1 Belongs to the IlvD Edd family - - - 9.977e-269 837.0
HFD1_k127_944673_10 Cupredoxin-like domain - - - 0.000000000000000000000000004393 115.0
HFD1_k127_944673_11 Peptidase family M23 - - - 0.0000000003883 64.0
HFD1_k127_944673_12 AAA ATPase domain - - - 0.00001405 48.0
HFD1_k127_944673_2 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 501.0
HFD1_k127_944673_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 463.0
HFD1_k127_944673_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 422.0
HFD1_k127_944673_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 338.0
HFD1_k127_944673_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004232 277.0
HFD1_k127_944673_7 Bacterial protein of unknown function (DUF898) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000135 273.0
HFD1_k127_944673_8 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003808 244.0
HFD1_k127_944673_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000001215 181.0
HFD1_k127_982321_0 peptidase, M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 564.0
HFD1_k127_982321_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 415.0
HFD1_k127_982321_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000023 264.0
HFD1_k127_982321_3 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000002834 207.0
HFD1_k127_982321_4 Protein of unknown function (DUF3225) - - - 0.00000000000000000000000000000000000000000000000000003937 194.0
HFD1_k127_98559_0 Belongs to the peptidase S16 family - - - 3.6e-317 990.0
HFD1_k127_98559_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.524e-280 868.0
HFD1_k127_98559_10 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 356.0
HFD1_k127_98559_11 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 350.0
HFD1_k127_98559_12 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 340.0
HFD1_k127_98559_13 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001641 284.0
HFD1_k127_98559_14 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002067 282.0
HFD1_k127_98559_15 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002341 278.0
HFD1_k127_98559_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000182 249.0
HFD1_k127_98559_17 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000004439 247.0
HFD1_k127_98559_18 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001018 238.0
HFD1_k127_98559_19 - - - - 0.0000000000000000000000001499 117.0
HFD1_k127_98559_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.117e-238 749.0
HFD1_k127_98559_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP - - - 1.204e-199 631.0
HFD1_k127_98559_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 546.0
HFD1_k127_98559_5 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 503.0
HFD1_k127_98559_6 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 442.0
HFD1_k127_98559_7 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 432.0
HFD1_k127_98559_8 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 433.0
HFD1_k127_98559_9 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 384.0